Structure of T. gondii PLP1 beta-rich domain

Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress.

SNAVGLTPQDLSALTGVTRNLPKQLTQATQVAWSGPPPGFAKCPGGQVVILGFAMHLNFKEPGTDNFRIISCPPGREKCD
GVGTASSETDEGRIYILCGEEPINEIQQVVAESPAHAGASVLEASCPDETVVVGGFGISVRGGSDGLDSFSIESCTTGQT
ICTKAPTRGSEKNFLWMMCVDKQYPGLRELVNVAELGSHGNANKRAVNSDGNVDVKCPANSSIVLGYVMEAHTNMQFVRD
KFLQCPENASECKMTGKGVDHGMLWLFDRHALFGWIICKTVNEPAMHVATDVGKAKGNGKKKKGRKGKNKTNAPNEVEEG
QQLGADSPSQVSVPADADSGPTSKTMSSLKLAPVKLLDL

100 mM sodium cacodylate, 0.8M sodium formate, 15% PEG 4000

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

Pore forming protein, toxin, perforin-like protein, beta-prism, LIPID BINDING PROTEIN

AVGLTPQDLSALTGVTRNLPKQLTQATQVAWSGPPPGFAKCPGGQVVILGFAMHLNFKEPGTDNFRIISCPPGREKCDGV
GTASSETDEGRIYILCGEEPINEIQQVVAESPAHAGASVLEASCPDETVVVGGFGISVRGGSDGLDSFSIESCTTGQTIC
TKAPTRGSEKNFLWMMCVDKQYPGLRELVNVAELGSHGNANKRAVNSDGNVDVKCPANSSIVLGYVMEAHTNMQFVRDKF
LQCPENASECKMTGKGVDHGMLWLFDRHALFGWIICKTVNEPAMHVATDVGKAKGNGKKKKGRKGKNKTNAPNEVEEGQQ
LGADSPSQVSVPADADSGPTSKTMSSLKLAPVKLLDL