CryoEM structure of human enterovirus D68 in complex with 6'-sialyl-N-acetyllactosamine

beta-D-galactose; D-galactose; galactose

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

N-acetylneuraminic acid; sialic acid; alpha-sialic acid; O-SIALIC ACID

Bypassing pan-enterovirus host factor PLA2G16.

On-the-fly CTF correction during 2D alignment and 3D reconstruction

N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose

IESIIKTATDTVKSEINAELGVVPSLNAVETGATSNTEPEEAIQTRTVINQHGVSETLVENFLSRAALVSKRSFEYKDHT
SSAAQTDKNFFKWTINTRSFVQLRRKLELFTYLRFDAEITILTTVAVNGSSNNTYMGLPNLTLQAMFVPTGALTPEKQDS
FHWQSGSNASVFFKISDPPARMTIPFMCINSAYSVFYDGFAGFEKSGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVY
MKPKHIKAWAPRPPRTLPYMSIANANYKGKKRAPNALNAIIGNRDSVKTMPHNIVTT

GVPTYLLPGSGQFLTTDDHSSAPVLPCFNPTPEMHIPGQVRNMLEVVQVESMMEINNTESAVGMERLKVDISALTDVDQL
LFNIPLDIQLDGPLRNTLVGNISRYYTHWSGSLEMTFMFCGSFMATGKLILCYTPPGGSCPTTRETAMLGTHIVWDFGLQ
SSVTLIIPWISGSHYRMFNNDAKSTNANVGYVTCFMQTNLIVPSESSDTCSLIGFIAAKDDFSLRLMRDSPDIGQIDHLH
AAEAAYQ

SPSAEACGYSDRVLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETATDRFYTLKSVKWEAGSTGWWW
KLPDALNNIGMFGQNVQHHYLYRSGFLIHVQCNATRFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPYV
LDDGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTLAIIPVVPLGTRTMSSMVPITVSIAPMCCEFN
GLRHAITQ

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

icosahedral asymmetric unit, std point frame

SPSAEACGYSDRVLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETATDRFYTLKSVKWEAGSTGWWW
KLPDALNNIGMFGQNVQHHYLYRSGFLIHVQCNATKFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPYV
LDDGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTLAIIPVVPLGTRTMSSMVPITVSIAPMCCEFN
GLRHAITQ