Carbonic anhydrase 2 in complex with 2-chloro-5'-O-sulfamoyladenosine

Synthesis, structure and bioactivity of primary sulfamate-containing natural products.

Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II

MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLK
GGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVV
DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK

Protein was at 10 mg/mL and was set up in 250 plus 250 nL drops with a reservoir of 50 mM Tris pH 8.0, 2.8 M ammonium sulfate at 8C

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

human carbonic anhydrase II; inhibitor; natural product, LYASE, LYASE-INHIBITOR complex