De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH1
De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
2.0% PEG1000, 1.0 M AmSO4 and 0.1 M HEPES pH 7.5
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
A-B chains paired with its closest symmetry-related equivalent A*-B* to form a 4-helix bundle; so do C-D in the same way.
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Protein Design, Helical Bundle, Metal Binding, DE NOVO PROTEIN
binding site for Di-peptide ACE B 0 and ILE B 1
binding site for Di-peptide LEU B 26 and NH2 B 27
binding site for Di-peptide ACE C 0 and ILE C 1
binding site for Di-peptide LEU C 26 and NH2 C 27
binding site for Di-peptide ACE D 0 and ILE D 1
binding site for Di-peptide LEU D 26 and NH2 D 27