Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
type: datablock
alternative label: 5WJJ
link to mmcif: 5WJJ.cif.gz
link to pdbml: 5WJJ.xml.gz
link to pdbml noatom: 5WJJ-noatom.xml.gz
link to pdbml extatom: 5WJJ-extatom.xml.gz
link to doi: doi:10.2210/pdb5WJJ/pdb
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5WJJ
type: atom sites
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
atom sites.entry id: 5WJJ
atom sites.fract transf matrix11: 0.014324
atom sites.fract transf matrix12: 0
atom sites.fract transf matrix13: 0
atom sites.fract transf matrix21: 0
atom sites.fract transf matrix22: 0.014291
atom sites.fract transf matrix23: 0
atom sites.fract transf matrix31: 0
atom sites.fract transf matrix32: 0
atom sites.fract transf matrix33: 0.013536
atom sites.fract transf vector1: 0
atom sites.fract transf vector2: 0
atom sites.fract transf vector3: 0

5WJJ
referenced by atom sites: 5WJJ
referenced by cell: 5WJJ
type: entry
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
entry.id: 5WJJ
referenced by exptl: 5WJJ,X-RAY DIFFRACTION
referenced by refine: 5WJJ,X-RAY DIFFRACTION
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referenced by struct keywords: 5WJJ
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referenced by pdbx database status: 5WJJ

http://rdf.wwpdb.org/pdb/5WJJ/atom_type/C
type: atom type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
atom type.symbol: C

http://rdf.wwpdb.org/pdb/5WJJ/atom_type/F
type: atom type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
atom type.symbol: F

http://rdf.wwpdb.org/pdb/5WJJ/atom_type/N
type: atom type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
atom type.symbol: N

http://rdf.wwpdb.org/pdb/5WJJ/atom_type/O
type: atom type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
atom type.symbol: O

http://rdf.wwpdb.org/pdb/5WJJ/atom_type/S
type: atom type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
atom type.symbol: S

http://rdf.wwpdb.org/pdb/5WJJ/audit_author/1
type: audit author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
audit author.pdbx ordinal: 1
audit author.name: Snell, G.P.

http://rdf.wwpdb.org/pdb/5WJJ/audit_author/2
type: audit author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
audit author.pdbx ordinal: 2
audit author.name: Okada, K.

http://rdf.wwpdb.org/pdb/5WJJ/audit_author/3
type: audit author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
audit author.pdbx ordinal: 3
audit author.name: Bragstad, K.

http://rdf.wwpdb.org/pdb/5WJJ/audit_author/4
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of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
audit author.pdbx ordinal: 4
audit author.name: Sang, B.-C.

mmcif pdbx.dic,5.387
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of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
audit conform.dict name: mmcif_pdbx.dic
audit conform.dict version: 5.387
audit conform.dict location: http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic

5WJJ
type: cell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
cell.entry id: 5WJJ
cell.z PDB: 4
cell.angle alpha: 90
cell.angle beta: 90
cell.angle gamma: 90
cell.length a: 69.813
cell.length b: 69.974
cell.length c: 73.878

ALA
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: ALA
chem comp.formula: C3 H7 N O2
chem comp.formula weight: 89.093
chem comp.mon nstd flag: y
chem comp.name: ALANINE
chem comp.type: L-peptide linking
link to chem comp: ALA
referenced by chem comp atom: HXT,ALA
referenced by chem comp bond: OXT,HXT,ALA
referenced by entity poly seq: 1,ALA,325
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/2
referenced by chem comp atom: N,ALA
referenced by chem comp atom: CA,ALA
referenced by chem comp atom: C,ALA
referenced by chem comp atom: O,ALA
referenced by chem comp atom: CB,ALA
referenced by chem comp atom: OXT,ALA
referenced by chem comp atom: H,ALA
referenced by chem comp atom: H2,ALA
referenced by chem comp atom: HA,ALA
referenced by chem comp atom: HB1,ALA
referenced by chem comp atom: HB2,ALA
referenced by chem comp atom: HB3,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: C,O,ALA
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA
referenced by chem comp bond: CB,HB3,ALA
referenced by entity poly seq: 1,ALA,2
referenced by entity poly seq: 1,ALA,39
referenced by entity poly seq: 1,ALA,45
referenced by entity poly seq: 1,ALA,46
referenced by entity poly seq: 1,ALA,56
referenced by entity poly seq: 1,ALA,70
referenced by entity poly seq: 1,ALA,98
referenced by entity poly seq: 1,ALA,116
referenced by entity poly seq: 1,ALA,149
referenced by entity poly seq: 1,ALA,162
referenced by entity poly seq: 1,ALA,177
referenced by entity poly seq: 1,ALA,189
referenced by entity poly seq: 1,ALA,195
referenced by entity poly seq: 1,ALA,219
referenced by entity poly seq: 1,ALA,249
referenced by entity poly seq: 1,ALA,260
referenced by entity poly seq: 1,ALA,276
referenced by entity poly seq: 1,ALA,282
referenced by entity poly seq: 1,ALA,286
referenced by entity poly seq: 1,ALA,304
referenced by entity poly seq: 1,ALA,305
referenced by entity poly seq: 1,ALA,307
referenced by entity poly seq: 1,ALA,309
referenced by entity poly seq: 1,ALA,311
referenced by entity poly seq: 1,ALA,314

AQY
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: AQY
chem comp.formula: C25 H19 F N6 O2
chem comp.formula weight: 454.456
chem comp.name: N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide
chem comp.type: non-polymer
link to chem comp: AQY
referenced by chem comp atom: H20,AQY
referenced by chem comp bond: C34,H20,AQY
referenced by chem comp atom: C4,AQY
referenced by chem comp atom: C5,AQY
referenced by chem comp atom: C6,AQY
referenced by chem comp atom: C7,AQY
referenced by chem comp atom: C13,AQY
referenced by chem comp atom: C17,AQY
referenced by chem comp atom: C20,AQY
referenced by chem comp atom: C22,AQY
referenced by chem comp atom: C24,AQY
referenced by chem comp atom: C26,AQY
referenced by chem comp atom: C28,AQY
referenced by chem comp atom: C1,AQY
referenced by chem comp atom: C2,AQY
referenced by chem comp atom: C3,AQY
referenced by chem comp atom: F8,AQY
referenced by chem comp atom: C9,AQY
referenced by chem comp atom: N10,AQY
referenced by chem comp atom: C11,AQY
referenced by chem comp atom: C12,AQY
referenced by chem comp atom: C14,AQY
referenced by chem comp atom: N15,AQY
referenced by chem comp atom: N16,AQY
referenced by chem comp atom: C18,AQY
referenced by chem comp atom: C19,AQY
referenced by chem comp atom: N21,AQY
referenced by chem comp atom: N23,AQY
referenced by chem comp atom: O25,AQY
referenced by chem comp atom: C27,AQY
referenced by chem comp atom: N29,AQY
referenced by chem comp atom: O30,AQY
referenced by chem comp atom: C31,AQY
referenced by chem comp atom: C32,AQY
referenced by chem comp atom: C33,AQY
referenced by chem comp atom: C34,AQY
referenced by chem comp atom: H1,AQY
referenced by chem comp atom: H2,AQY
referenced by chem comp atom: H3,AQY
referenced by chem comp atom: H4,AQY
referenced by chem comp atom: H5,AQY
referenced by chem comp atom: H6,AQY
referenced by chem comp atom: H7,AQY
referenced by chem comp atom: H8,AQY
referenced by chem comp atom: H9,AQY
referenced by chem comp atom: H10,AQY
referenced by chem comp atom: H11,AQY
referenced by chem comp atom: H12,AQY
referenced by chem comp atom: H13,AQY
referenced by chem comp atom: H14,AQY
referenced by chem comp atom: H16,AQY
referenced by chem comp atom: H17,AQY
referenced by chem comp atom: H18,AQY
referenced by chem comp atom: H19,AQY
referenced by chem comp bond: C12,C13,AQY
referenced by chem comp bond: C12,C11,AQY
referenced by chem comp bond: C13,C14,AQY
referenced by chem comp bond: C11,N10,AQY
referenced by chem comp bond: C11,N16,AQY
referenced by chem comp bond: C14,N15,AQY
referenced by chem comp bond: N10,C9,AQY
referenced by chem comp bond: N16,N15,AQY
referenced by chem comp bond: N16,C17,AQY
referenced by chem comp bond: C9,C4,AQY
referenced by chem comp bond: C9,C17,AQY
referenced by chem comp bond: C3,C4,AQY
referenced by chem comp bond: C3,C2,AQY
referenced by chem comp bond: C1,C2,AQY
referenced by chem comp bond: C4,C5,AQY
referenced by chem comp bond: C17,C18,AQY
referenced by chem comp bond: C2,C7,AQY
referenced by chem comp bond: C5,C6,AQY

ARG
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: ARG
chem comp.formula: C6 H15 N4 O2 1
chem comp.formula weight: 175.209
chem comp.mon nstd flag: y
chem comp.name: ARGININE
chem comp.type: L-peptide linking
link to chem comp: ARG
referenced by chem comp atom: HXT,ARG
referenced by chem comp bond: OXT,HXT,ARG
referenced by entity poly seq: 1,ARG,335
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/6
referenced by chem comp atom: N,ARG
referenced by chem comp atom: CA,ARG
referenced by chem comp atom: C,ARG
referenced by chem comp atom: O,ARG
referenced by chem comp atom: CB,ARG
referenced by chem comp atom: CG,ARG
referenced by chem comp atom: CD,ARG
referenced by chem comp atom: NE,ARG
referenced by chem comp atom: CZ,ARG
referenced by chem comp atom: NH1,ARG
referenced by chem comp atom: NH2,ARG
referenced by chem comp atom: OXT,ARG
referenced by chem comp atom: H,ARG
referenced by chem comp atom: H2,ARG
referenced by chem comp atom: HA,ARG
referenced by chem comp atom: HB2,ARG
referenced by chem comp atom: HB3,ARG
referenced by chem comp atom: HG2,ARG
referenced by chem comp atom: HG3,ARG
referenced by chem comp atom: HD2,ARG
referenced by chem comp atom: HD3,ARG
referenced by chem comp atom: HE,ARG
referenced by chem comp atom: HH11,ARG
referenced by chem comp atom: HH12,ARG
referenced by chem comp atom: HH21,ARG
referenced by chem comp atom: HH22,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: C,O,ARG
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH1,HH11,ARG
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: NH2,HH21,ARG
referenced by chem comp bond: NH2,HH22,ARG
referenced by entity poly seq: 1,ARG,10
referenced by entity poly seq: 1,ARG,15
referenced by entity poly seq: 1,ARG,28
referenced by entity poly seq: 1,ARG,54
referenced by entity poly seq: 1,ARG,62
referenced by entity poly seq: 1,ARG,72
referenced by entity poly seq: 1,ARG,75
referenced by entity poly seq: 1,ARG,78
referenced by entity poly seq: 1,ARG,99
referenced by entity poly seq: 1,ARG,141
referenced by entity poly seq: 1,ARG,154
referenced by entity poly seq: 1,ARG,178
referenced by entity poly seq: 1,ARG,191
referenced by entity poly seq: 1,ARG,194
referenced by entity poly seq: 1,ARG,225
referenced by entity poly seq: 1,ARG,242

ASN
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: ASN
chem comp.formula: C4 H8 N2 O3
chem comp.formula weight: 132.118
chem comp.mon nstd flag: y
chem comp.name: ASPARAGINE
chem comp.type: L-peptide linking
link to chem comp: ASN
referenced by chem comp atom: HXT,ASN
referenced by chem comp bond: OXT,HXT,ASN
referenced by entity poly seq: 1,ASN,283
referenced by chem comp atom: N,ASN
referenced by chem comp atom: CA,ASN
referenced by chem comp atom: C,ASN
referenced by chem comp atom: O,ASN
referenced by chem comp atom: CB,ASN
referenced by chem comp atom: CG,ASN
referenced by chem comp atom: OD1,ASN
referenced by chem comp atom: ND2,ASN
referenced by chem comp atom: OXT,ASN
referenced by chem comp atom: H,ASN
referenced by chem comp atom: H2,ASN
referenced by chem comp atom: HA,ASN
referenced by chem comp atom: HB2,ASN
referenced by chem comp atom: HB3,ASN
referenced by chem comp atom: HD21,ASN
referenced by chem comp atom: HD22,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: C,O,ASN
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CG,OD1,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN
referenced by chem comp bond: ND2,HD22,ASN
referenced by entity poly seq: 1,ASN,19
referenced by entity poly seq: 1,ASN,31
referenced by entity poly seq: 1,ASN,87
referenced by entity poly seq: 1,ASN,105
referenced by entity poly seq: 1,ASN,119
referenced by entity poly seq: 1,ASN,120
referenced by entity poly seq: 1,ASN,160
referenced by entity poly seq: 1,ASN,164
referenced by entity poly seq: 1,ASN,201
referenced by entity poly seq: 1,ASN,206
referenced by entity poly seq: 1,ASN,262
referenced by entity poly seq: 1,ASN,274
referenced by entity poly seq: 1,ASN,277

ASP
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: ASP
chem comp.formula: C4 H7 N O4
chem comp.formula weight: 133.103
chem comp.mon nstd flag: y
chem comp.name: ASPARTIC ACID
chem comp.type: L-peptide linking
link to chem comp: ASP
referenced by chem comp atom: HXT,ASP
referenced by chem comp bond: OXT,HXT,ASP
referenced by entity poly seq: 1,ASP,359
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/21
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/9
referenced by chem comp atom: N,ASP
referenced by chem comp atom: CA,ASP
referenced by chem comp atom: C,ASP
referenced by chem comp atom: O,ASP
referenced by chem comp atom: CB,ASP
referenced by chem comp atom: CG,ASP
referenced by chem comp atom: OD1,ASP
referenced by chem comp atom: OD2,ASP
referenced by chem comp atom: OXT,ASP
referenced by chem comp atom: H,ASP
referenced by chem comp atom: H2,ASP
referenced by chem comp atom: HA,ASP
referenced by chem comp atom: HB2,ASP
referenced by chem comp atom: HB3,ASP
referenced by chem comp atom: HD2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: C,O,ASP
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CG,OD1,ASP
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: OD2,HD2,ASP
referenced by entity poly seq: 1,ASP,48
referenced by entity poly seq: 1,ASP,93
referenced by entity poly seq: 1,ASP,106
referenced by entity poly seq: 1,ASP,117
referenced by entity poly seq: 1,ASP,129
referenced by entity poly seq: 1,ASP,130
referenced by entity poly seq: 1,ASP,150
referenced by entity poly seq: 1,ASP,155
referenced by entity poly seq: 1,ASP,166
referenced by entity poly seq: 1,ASP,173
referenced by entity poly seq: 1,ASP,181
referenced by entity poly seq: 1,ASP,182
referenced by entity poly seq: 1,ASP,210
referenced by entity poly seq: 1,ASP,232
referenced by entity poly seq: 1,ASP,235
referenced by entity poly seq: 1,ASP,288
referenced by entity poly seq: 1,ASP,297
referenced by entity poly seq: 1,ASP,299
referenced by entity poly seq: 1,ASP,318
referenced by entity poly seq: 1,ASP,320
referenced by entity poly seq: 1,ASP,321
referenced by entity poly seq: 1,ASP,326
referenced by entity poly seq: 1,ASP,329
referenced by entity poly seq: 1,ASP,336
referenced by entity poly seq: 1,ASP,340
referenced by entity poly seq: 1,ASP,348
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/7
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/8

CYS
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: CYS
chem comp.formula: C3 H7 N O2 S
chem comp.formula weight: 121.158
chem comp.mon nstd flag: y
chem comp.name: CYSTEINE
chem comp.type: L-peptide linking
link to chem comp: CYS
referenced by chem comp atom: HXT,CYS
referenced by chem comp bond: OXT,HXT,CYS
referenced by entity poly seq: 1,CYS,216
referenced by chem comp atom: N,CYS
referenced by chem comp atom: CA,CYS
referenced by chem comp atom: C,CYS
referenced by chem comp atom: O,CYS
referenced by chem comp atom: CB,CYS
referenced by chem comp atom: SG,CYS
referenced by chem comp atom: OXT,CYS
referenced by chem comp atom: H,CYS
referenced by chem comp atom: H2,CYS
referenced by chem comp atom: HA,CYS
referenced by chem comp atom: HB2,CYS
referenced by chem comp atom: HB3,CYS
referenced by chem comp atom: HG,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: C,O,CYS
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: SG,HG,CYS
referenced by entity poly seq: 1,CYS,44

GLN
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: GLN
chem comp.formula: C5 H10 N2 O3
chem comp.formula weight: 146.144
chem comp.mon nstd flag: y
chem comp.name: GLUTAMINE
chem comp.type: L-peptide linking
link to chem comp: GLN
referenced by chem comp atom: HXT,GLN
referenced by chem comp bond: OXT,HXT,GLN
referenced by entity poly seq: 1,GLN,360
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/22
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/17
referenced by chem comp atom: N,GLN
referenced by chem comp atom: CA,GLN
referenced by chem comp atom: C,GLN
referenced by chem comp atom: O,GLN
referenced by chem comp atom: CB,GLN
referenced by chem comp atom: CG,GLN
referenced by chem comp atom: CD,GLN
referenced by chem comp atom: OE1,GLN
referenced by chem comp atom: NE2,GLN
referenced by chem comp atom: OXT,GLN
referenced by chem comp atom: H,GLN
referenced by chem comp atom: H2,GLN
referenced by chem comp atom: HA,GLN
referenced by chem comp atom: HB2,GLN
referenced by chem comp atom: HB3,GLN
referenced by chem comp atom: HG2,GLN
referenced by chem comp atom: HG3,GLN
referenced by chem comp atom: HE21,GLN
referenced by chem comp atom: HE22,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: C,O,GLN
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CD,OE1,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN
referenced by chem comp bond: NE2,HE22,GLN
referenced by entity poly seq: 1,GLN,8
referenced by entity poly seq: 1,GLN,16
referenced by entity poly seq: 1,GLN,30
referenced by entity poly seq: 1,GLN,65
referenced by entity poly seq: 1,GLN,125
referenced by entity poly seq: 1,GLN,133
referenced by entity poly seq: 1,GLN,138
referenced by entity poly seq: 1,GLN,207
referenced by entity poly seq: 1,GLN,236
referenced by entity poly seq: 1,GLN,265
referenced by entity poly seq: 1,GLN,269
referenced by entity poly seq: 1,GLN,306
referenced by entity poly seq: 1,GLN,315
referenced by entity poly seq: 1,GLN,330
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/14
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/15
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/16
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/8

GLU
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: GLU
chem comp.formula: C5 H9 N O4
chem comp.formula weight: 147.129
chem comp.mon nstd flag: y
chem comp.name: GLUTAMIC ACID
chem comp.type: L-peptide linking
link to chem comp: GLU
referenced by chem comp atom: HXT,GLU
referenced by chem comp bond: OXT,HXT,GLU
referenced by entity poly seq: 1,GLU,364
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/26
referenced by chem comp atom: N,GLU
referenced by chem comp atom: CA,GLU
referenced by chem comp atom: C,GLU
referenced by chem comp atom: O,GLU
referenced by chem comp atom: CB,GLU
referenced by chem comp atom: CG,GLU
referenced by chem comp atom: CD,GLU
referenced by chem comp atom: OE1,GLU
referenced by chem comp atom: OE2,GLU
referenced by chem comp atom: OXT,GLU
referenced by chem comp atom: H,GLU
referenced by chem comp atom: H2,GLU
referenced by chem comp atom: HA,GLU
referenced by chem comp atom: HB2,GLU
referenced by chem comp atom: HB3,GLU
referenced by chem comp atom: HG2,GLU
referenced by chem comp atom: HG3,GLU
referenced by chem comp atom: HE2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: C,O,GLU
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CD,OE1,GLU
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: OE2,HE2,GLU
referenced by entity poly seq: 1,GLU,9
referenced by entity poly seq: 1,GLU,17
referenced by entity poly seq: 1,GLU,24
referenced by entity poly seq: 1,GLU,27
referenced by entity poly seq: 1,GLU,76
referenced by entity poly seq: 1,GLU,86
referenced by entity poly seq: 1,GLU,102
referenced by entity poly seq: 1,GLU,103
referenced by entity poly seq: 1,GLU,165
referenced by entity poly seq: 1,GLU,168
referenced by entity poly seq: 1,GLU,183
referenced by entity poly seq: 1,GLU,197
referenced by entity poly seq: 1,GLU,220
referenced by entity poly seq: 1,GLU,250
referenced by entity poly seq: 1,GLU,258
referenced by entity poly seq: 1,GLU,291
referenced by entity poly seq: 1,GLU,322
referenced by entity poly seq: 1,GLU,333
referenced by entity poly seq: 1,GLU,341
referenced by entity poly seq: 1,GLU,349
referenced by entity poly seq: 1,GLU,361
referenced by entity poly seq: 1,GLU,362
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/9
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/10
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/23
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/24

GLY
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: GLY
chem comp.formula: C2 H5 N O2
chem comp.formula weight: 75.067
chem comp.mon nstd flag: y
chem comp.name: GLYCINE
chem comp.type: peptide linking
link to chem comp: GLY
referenced by chem comp atom: HXT,GLY
referenced by chem comp bond: OXT,HXT,GLY
referenced by entity poly seq: 1,GLY,281
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/13
referenced by chem comp atom: N,GLY
referenced by chem comp atom: CA,GLY
referenced by chem comp atom: C,GLY
referenced by chem comp atom: O,GLY
referenced by chem comp atom: OXT,GLY
referenced by chem comp atom: H,GLY
referenced by chem comp atom: H2,GLY
referenced by chem comp atom: HA2,GLY
referenced by chem comp atom: HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: C,O,GLY
referenced by chem comp bond: C,OXT,GLY
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,GLY,4
referenced by entity poly seq: 1,GLY,36
referenced by entity poly seq: 1,GLY,38
referenced by entity poly seq: 1,GLY,41
referenced by entity poly seq: 1,GLY,52
referenced by entity poly seq: 1,GLY,90
referenced by entity poly seq: 1,GLY,115
referenced by entity poly seq: 1,GLY,142
referenced by entity poly seq: 1,GLY,175
referenced by entity poly seq: 1,GLY,186
referenced by entity poly seq: 1,GLY,215
referenced by entity poly seq: 1,GLY,224
referenced by entity poly seq: 1,GLY,230
referenced by entity poly seq: 1,GLY,245
referenced by entity poly seq: 1,GLY,248
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/1
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/4

HIS
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: HIS
chem comp.formula: C6 H10 N3 O2 1
chem comp.formula weight: 156.162
chem comp.mon nstd flag: y
chem comp.name: HISTIDINE
chem comp.type: L-peptide linking
link to chem comp: HIS
referenced by chem comp atom: HXT,HIS
referenced by chem comp bond: OXT,HXT,HIS
referenced by entity poly seq: 1,HIS,317
referenced by chem comp atom: N,HIS
referenced by chem comp atom: CA,HIS
referenced by chem comp atom: C,HIS
referenced by chem comp atom: O,HIS
referenced by chem comp atom: CB,HIS
referenced by chem comp atom: CG,HIS
referenced by chem comp atom: ND1,HIS
referenced by chem comp atom: CD2,HIS
referenced by chem comp atom: CE1,HIS
referenced by chem comp atom: NE2,HIS
referenced by chem comp atom: OXT,HIS
referenced by chem comp atom: H,HIS
referenced by chem comp atom: H2,HIS
referenced by chem comp atom: HA,HIS
referenced by chem comp atom: HB2,HIS
referenced by chem comp atom: HB3,HIS
referenced by chem comp atom: HD1,HIS
referenced by chem comp atom: HD2,HIS
referenced by chem comp atom: HE1,HIS
referenced by chem comp atom: HE2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: C,O,HIS
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CD2,NE2,HIS
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: NE2,HE2,HIS
referenced by entity poly seq: 1,HIS,69
referenced by entity poly seq: 1,HIS,82
referenced by entity poly seq: 1,HIS,85
referenced by entity poly seq: 1,HIS,112
referenced by entity poly seq: 1,HIS,131
referenced by entity poly seq: 1,HIS,147
referenced by entity poly seq: 1,HIS,153
referenced by entity poly seq: 1,HIS,179
referenced by entity poly seq: 1,HIS,204
referenced by entity poly seq: 1,HIS,233
referenced by entity poly seq: 1,HIS,310

HOH
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: HOH
chem comp.formula: H2 O
chem comp.formula weight: 18.015
chem comp.name: WATER
chem comp.type: non-polymer
link to chem comp: HOH
referenced by chem comp atom: H2,HOH
referenced by chem comp bond: O,H2,HOH
referenced by pdbx distant solvent atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_distant_solvent_atoms/1
referenced by chem comp atom: O,HOH
referenced by chem comp atom: H1,HOH
referenced by chem comp bond: O,H1,HOH

ILE
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: ILE
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: ISOLEUCINE
chem comp.type: L-peptide linking
link to chem comp: ILE
referenced by chem comp atom: HXT,ILE
referenced by chem comp bond: OXT,HXT,ILE
referenced by entity poly seq: 1,ILE,351
referenced by chem comp atom: N,ILE
referenced by chem comp atom: CA,ILE
referenced by chem comp atom: C,ILE
referenced by chem comp atom: O,ILE
referenced by chem comp atom: CB,ILE
referenced by chem comp atom: CG1,ILE
referenced by chem comp atom: CG2,ILE
referenced by chem comp atom: CD1,ILE
referenced by chem comp atom: OXT,ILE
referenced by chem comp atom: H,ILE
referenced by chem comp atom: H2,ILE
referenced by chem comp atom: HA,ILE
referenced by chem comp atom: HB,ILE
referenced by chem comp atom: HG12,ILE
referenced by chem comp atom: HG13,ILE
referenced by chem comp atom: HG21,ILE
referenced by chem comp atom: HG22,ILE
referenced by chem comp atom: HG23,ILE
referenced by chem comp atom: HD11,ILE
referenced by chem comp atom: HD12,ILE
referenced by chem comp atom: HD13,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: C,O,ILE
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE
referenced by chem comp bond: CD1,HD13,ILE
referenced by entity poly seq: 1,ILE,22
referenced by entity poly seq: 1,ILE,67
referenced by entity poly seq: 1,ILE,68
referenced by entity poly seq: 1,ILE,89
referenced by entity poly seq: 1,ILE,121
referenced by entity poly seq: 1,ILE,136
referenced by entity poly seq: 1,ILE,139
referenced by entity poly seq: 1,ILE,146
referenced by entity poly seq: 1,ILE,151
referenced by entity poly seq: 1,ILE,152
referenced by entity poly seq: 1,ILE,171
referenced by entity poly seq: 1,ILE,198
referenced by entity poly seq: 1,ILE,211
referenced by entity poly seq: 1,ILE,217
referenced by entity poly seq: 1,ILE,234
referenced by entity poly seq: 1,ILE,240
referenced by entity poly seq: 1,ILE,255
referenced by entity poly seq: 1,ILE,264
referenced by entity poly seq: 1,ILE,280
referenced by entity poly seq: 1,ILE,302
referenced by entity poly seq: 1,ILE,339

LEU
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: LEU
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: LEUCINE
chem comp.type: L-peptide linking
link to chem comp: LEU
referenced by chem comp atom: HXT,LEU
referenced by chem comp bond: OXT,HXT,LEU
referenced by entity poly seq: 1,LEU,358
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/20
referenced by chem comp atom: N,LEU
referenced by chem comp atom: CA,LEU
referenced by chem comp atom: C,LEU
referenced by chem comp atom: O,LEU
referenced by chem comp atom: CB,LEU
referenced by chem comp atom: CG,LEU
referenced by chem comp atom: CD1,LEU
referenced by chem comp atom: CD2,LEU
referenced by chem comp atom: OXT,LEU
referenced by chem comp atom: H,LEU
referenced by chem comp atom: H2,LEU
referenced by chem comp atom: HA,LEU
referenced by chem comp atom: HB2,LEU
referenced by chem comp atom: HB3,LEU
referenced by chem comp atom: HG,LEU
referenced by chem comp atom: HD11,LEU
referenced by chem comp atom: HD12,LEU
referenced by chem comp atom: HD13,LEU
referenced by chem comp atom: HD21,LEU
referenced by chem comp atom: HD22,LEU
referenced by chem comp atom: HD23,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: C,O,LEU
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU
referenced by chem comp bond: CD2,HD23,LEU
referenced by entity poly seq: 1,LEU,18
referenced by entity poly seq: 1,LEU,32
referenced by entity poly seq: 1,LEU,53
referenced by entity poly seq: 1,LEU,60
referenced by entity poly seq: 1,LEU,77
referenced by entity poly seq: 1,LEU,79
referenced by entity poly seq: 1,LEU,80
referenced by entity poly seq: 1,LEU,91
referenced by entity poly seq: 1,LEU,92
referenced by entity poly seq: 1,LEU,101
referenced by entity poly seq: 1,LEU,109
referenced by entity poly seq: 1,LEU,113
referenced by entity poly seq: 1,LEU,118
referenced by entity poly seq: 1,LEU,127
referenced by entity poly seq: 1,LEU,135
referenced by entity poly seq: 1,LEU,140
referenced by entity poly seq: 1,LEU,143
referenced by entity poly seq: 1,LEU,156
referenced by entity poly seq: 1,LEU,161
referenced by entity poly seq: 1,LEU,169
referenced by entity poly seq: 1,LEU,172
referenced by entity poly seq: 1,LEU,176
referenced by entity poly seq: 1,LEU,200
referenced by entity poly seq: 1,LEU,221
referenced by entity poly seq: 1,LEU,222
referenced by entity poly seq: 1,LEU,227

LYS
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: LYS
chem comp.formula: C6 H15 N2 O2 1
chem comp.formula weight: 147.195
chem comp.mon nstd flag: y
chem comp.name: LYSINE
chem comp.type: L-peptide linking
link to chem comp: LYS
referenced by chem comp atom: HXT,LYS
referenced by chem comp bond: OXT,HXT,LYS
referenced by entity poly seq: 1,LYS,343
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/13
referenced by chem comp atom: N,LYS
referenced by chem comp atom: CA,LYS
referenced by chem comp atom: C,LYS
referenced by chem comp atom: O,LYS
referenced by chem comp atom: CB,LYS
referenced by chem comp atom: CG,LYS
referenced by chem comp atom: CD,LYS
referenced by chem comp atom: CE,LYS
referenced by chem comp atom: NZ,LYS
referenced by chem comp atom: OXT,LYS
referenced by chem comp atom: H,LYS
referenced by chem comp atom: H2,LYS
referenced by chem comp atom: HA,LYS
referenced by chem comp atom: HB2,LYS
referenced by chem comp atom: HB3,LYS
referenced by chem comp atom: HG2,LYS
referenced by chem comp atom: HG3,LYS
referenced by chem comp atom: HD2,LYS
referenced by chem comp atom: HD3,LYS
referenced by chem comp atom: HE2,LYS
referenced by chem comp atom: HE3,LYS
referenced by chem comp atom: HZ1,LYS
referenced by chem comp atom: HZ2,LYS
referenced by chem comp atom: HZ3,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: C,O,LYS
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS
referenced by chem comp bond: NZ,HZ3,LYS
referenced by entity poly seq: 1,LYS,20
referenced by entity poly seq: 1,LYS,50
referenced by entity poly seq: 1,LYS,58
referenced by entity poly seq: 1,LYS,59
referenced by entity poly seq: 1,LYS,71
referenced by entity poly seq: 1,LYS,81
referenced by entity poly seq: 1,LYS,84
referenced by entity poly seq: 1,LYS,123
referenced by entity poly seq: 1,LYS,126
referenced by entity poly seq: 1,LYS,144
referenced by entity poly seq: 1,LYS,157
referenced by entity poly seq: 1,LYS,170
referenced by entity poly seq: 1,LYS,238
referenced by entity poly seq: 1,LYS,253
referenced by entity poly seq: 1,LYS,254
referenced by entity poly seq: 1,LYS,272
referenced by entity poly seq: 1,LYS,292
referenced by entity poly seq: 1,LYS,300
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/10
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/11

MET
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: MET
chem comp.formula: C5 H11 N O2 S
chem comp.formula weight: 149.211
chem comp.mon nstd flag: y
chem comp.name: METHIONINE
chem comp.type: L-peptide linking
link to chem comp: MET
referenced by chem comp atom: HXT,MET
referenced by chem comp bond: OXT,HXT,MET
referenced by entity poly seq: 1,MET,363
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/25
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/20
referenced by chem comp atom: N,MET
referenced by chem comp atom: CA,MET
referenced by chem comp atom: C,MET
referenced by chem comp atom: O,MET
referenced by chem comp atom: CB,MET
referenced by chem comp atom: CG,MET
referenced by chem comp atom: SD,MET
referenced by chem comp atom: CE,MET
referenced by chem comp atom: OXT,MET
referenced by chem comp atom: H,MET
referenced by chem comp atom: H2,MET
referenced by chem comp atom: HA,MET
referenced by chem comp atom: HB2,MET
referenced by chem comp atom: HB3,MET
referenced by chem comp atom: HG2,MET
referenced by chem comp atom: HG3,MET
referenced by chem comp atom: HE1,MET
referenced by chem comp atom: HE2,MET
referenced by chem comp atom: HE3,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: C,O,MET
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET
referenced by chem comp bond: CE,HE3,MET
referenced by entity poly seq: 1,MET,3
referenced by entity poly seq: 1,MET,6
referenced by entity poly seq: 1,MET,83
referenced by entity poly seq: 1,MET,114
referenced by entity poly seq: 1,MET,184
referenced by entity poly seq: 1,MET,199
referenced by entity poly seq: 1,MET,203
referenced by entity poly seq: 1,MET,218
referenced by entity poly seq: 1,MET,270
referenced by entity poly seq: 1,MET,273
referenced by entity poly seq: 1,MET,293
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/18
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/19
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/3
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/6
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/11
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/16

PHE
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: PHE
chem comp.formula: C9 H11 N O2
chem comp.formula weight: 165.189
chem comp.mon nstd flag: y
chem comp.name: PHENYLALANINE
chem comp.type: L-peptide linking
link to chem comp: PHE
referenced by chem comp atom: HXT,PHE
referenced by chem comp bond: OXT,HXT,PHE
referenced by entity poly seq: 1,PHE,353
referenced by chem comp atom: N,PHE
referenced by chem comp atom: CA,PHE
referenced by chem comp atom: C,PHE
referenced by chem comp atom: O,PHE
referenced by chem comp atom: CB,PHE
referenced by chem comp atom: CG,PHE
referenced by chem comp atom: CD1,PHE
referenced by chem comp atom: CD2,PHE
referenced by chem comp atom: CE1,PHE
referenced by chem comp atom: CE2,PHE
referenced by chem comp atom: CZ,PHE
referenced by chem comp atom: OXT,PHE
referenced by chem comp atom: H,PHE
referenced by chem comp atom: H2,PHE
referenced by chem comp atom: HA,PHE
referenced by chem comp atom: HB2,PHE
referenced by chem comp atom: HB3,PHE
referenced by chem comp atom: HD1,PHE
referenced by chem comp atom: HD2,PHE
referenced by chem comp atom: HE1,PHE
referenced by chem comp atom: HE2,PHE
referenced by chem comp atom: HZ,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: C,O,PHE
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CE1,CZ,PHE
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CZ,HZ,PHE
referenced by entity poly seq: 1,PHE,13
referenced by entity poly seq: 1,PHE,47
referenced by entity poly seq: 1,PHE,64
referenced by entity poly seq: 1,PHE,95
referenced by entity poly seq: 1,PHE,104
referenced by entity poly seq: 1,PHE,134
referenced by entity poly seq: 1,PHE,174
referenced by entity poly seq: 1,PHE,228
referenced by entity poly seq: 1,PHE,275
referenced by entity poly seq: 1,PHE,279
referenced by entity poly seq: 1,PHE,313
referenced by entity poly seq: 1,PHE,332

PRO
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: PRO
chem comp.formula: C5 H9 N O2
chem comp.formula weight: 115.13
chem comp.mon nstd flag: y
chem comp.name: PROLINE
chem comp.type: L-peptide linking
link to chem comp: PRO
referenced by chem comp atom: HXT,PRO
referenced by chem comp bond: OXT,HXT,PRO
referenced by entity poly seq: 1,PRO,357
referenced by chem comp atom: N,PRO
referenced by chem comp atom: CA,PRO
referenced by chem comp atom: C,PRO
referenced by chem comp atom: O,PRO
referenced by chem comp atom: CB,PRO
referenced by chem comp atom: CG,PRO
referenced by chem comp atom: CD,PRO
referenced by chem comp atom: OXT,PRO
referenced by chem comp atom: H,PRO
referenced by chem comp atom: HA,PRO
referenced by chem comp atom: HB2,PRO
referenced by chem comp atom: HB3,PRO
referenced by chem comp atom: HG2,PRO
referenced by chem comp atom: HG3,PRO
referenced by chem comp atom: HD2,PRO
referenced by chem comp atom: HD3,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: C,O,PRO
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CD,HD2,PRO
referenced by chem comp bond: CD,HD3,PRO
referenced by entity poly seq: 1,PRO,11
referenced by entity poly seq: 1,PRO,26
referenced by entity poly seq: 1,PRO,34
referenced by entity poly seq: 1,PRO,63
referenced by entity poly seq: 1,PRO,97
referenced by entity poly seq: 1,PRO,158
referenced by entity poly seq: 1,PRO,196
referenced by entity poly seq: 1,PRO,229
referenced by entity poly seq: 1,PRO,247
referenced by entity poly seq: 1,PRO,271
referenced by entity poly seq: 1,PRO,284
referenced by entity poly seq: 1,PRO,319
referenced by entity poly seq: 1,PRO,323
referenced by entity poly seq: 1,PRO,327
referenced by entity poly seq: 1,PRO,355
referenced by entity poly seq: 1,PRO,356

SER
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: SER
chem comp.formula: C3 H7 N O3
chem comp.formula weight: 105.093
chem comp.mon nstd flag: y
chem comp.name: SERINE
chem comp.type: L-peptide linking
link to chem comp: SER
referenced by chem comp atom: HXT,SER
referenced by chem comp bond: OXT,HXT,SER
referenced by entity poly seq: 1,SER,365
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/27
referenced by chem comp atom: N,SER
referenced by chem comp atom: CA,SER
referenced by chem comp atom: C,SER
referenced by chem comp atom: O,SER
referenced by chem comp atom: CB,SER
referenced by chem comp atom: OG,SER
referenced by chem comp atom: OXT,SER
referenced by chem comp atom: H,SER
referenced by chem comp atom: H2,SER
referenced by chem comp atom: HA,SER
referenced by chem comp atom: HB2,SER
referenced by chem comp atom: HB3,SER
referenced by chem comp atom: HG,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: C,O,SER
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: OG,HG,SER
referenced by entity poly seq: 1,SER,5
referenced by entity poly seq: 1,SER,7
referenced by entity poly seq: 1,SER,33
referenced by entity poly seq: 1,SER,37
referenced by entity poly seq: 1,SER,42
referenced by entity poly seq: 1,SER,61
referenced by entity poly seq: 1,SER,66
referenced by entity poly seq: 1,SER,100
referenced by entity poly seq: 1,SER,124
referenced by entity poly seq: 1,SER,148
referenced by entity poly seq: 1,SER,159
referenced by entity poly seq: 1,SER,167
referenced by entity poly seq: 1,SER,213
referenced by entity poly seq: 1,SER,256
referenced by entity poly seq: 1,SER,257
referenced by entity poly seq: 1,SER,259
referenced by entity poly seq: 1,SER,266
referenced by entity poly seq: 1,SER,298
referenced by entity poly seq: 1,SER,331
referenced by entity poly seq: 1,SER,334
referenced by entity poly seq: 1,SER,344
referenced by entity poly seq: 1,SER,352
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/5
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/7
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/17

THR
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: THR
chem comp.formula: C4 H9 N O3
chem comp.formula weight: 119.119
chem comp.mon nstd flag: y
chem comp.name: THREONINE
chem comp.type: L-peptide linking
link to chem comp: THR
referenced by chem comp atom: HXT,THR
referenced by chem comp bond: OXT,HXT,THR
referenced by entity poly seq: 1,THR,346
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/19
referenced by chem comp atom: N,THR
referenced by chem comp atom: CA,THR
referenced by chem comp atom: C,THR
referenced by chem comp atom: O,THR
referenced by chem comp atom: CB,THR
referenced by chem comp atom: OG1,THR
referenced by chem comp atom: CG2,THR
referenced by chem comp atom: OXT,THR
referenced by chem comp atom: H,THR
referenced by chem comp atom: H2,THR
referenced by chem comp atom: HA,THR
referenced by chem comp atom: HB,THR
referenced by chem comp atom: HG1,THR
referenced by chem comp atom: HG21,THR
referenced by chem comp atom: HG22,THR
referenced by chem comp atom: HG23,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: C,O,THR
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR
referenced by chem comp bond: CG2,HG23,THR
referenced by entity poly seq: 1,THR,12
referenced by entity poly seq: 1,THR,21
referenced by entity poly seq: 1,THR,49
referenced by entity poly seq: 1,THR,51
referenced by entity poly seq: 1,THR,73
referenced by entity poly seq: 1,THR,96
referenced by entity poly seq: 1,THR,111
referenced by entity poly seq: 1,THR,128
referenced by entity poly seq: 1,THR,180
referenced by entity poly seq: 1,THR,185
referenced by entity poly seq: 1,THR,190
referenced by entity poly seq: 1,THR,208
referenced by entity poly seq: 1,THR,223
referenced by entity poly seq: 1,THR,226
referenced by entity poly seq: 1,THR,231
referenced by entity poly seq: 1,THR,246
referenced by entity poly seq: 1,THR,268
referenced by entity poly seq: 1,THR,303
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/12

TRP
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: TRP
chem comp.formula: C11 H12 N2 O2
chem comp.formula weight: 204.225
chem comp.mon nstd flag: y
chem comp.name: TRYPTOPHAN
chem comp.type: L-peptide linking
link to chem comp: TRP
referenced by chem comp atom: HXT,TRP
referenced by chem comp bond: OXT,HXT,TRP
referenced by entity poly seq: 1,TRP,342
referenced by chem comp atom: N,TRP
referenced by chem comp atom: CA,TRP
referenced by chem comp atom: C,TRP
referenced by chem comp atom: O,TRP
referenced by chem comp atom: CB,TRP
referenced by chem comp atom: CG,TRP
referenced by chem comp atom: CD1,TRP
referenced by chem comp atom: CD2,TRP
referenced by chem comp atom: NE1,TRP
referenced by chem comp atom: CE2,TRP
referenced by chem comp atom: CE3,TRP
referenced by chem comp atom: CZ2,TRP
referenced by chem comp atom: CZ3,TRP
referenced by chem comp atom: CH2,TRP
referenced by chem comp atom: OXT,TRP
referenced by chem comp atom: H,TRP
referenced by chem comp atom: H2,TRP
referenced by chem comp atom: HA,TRP
referenced by chem comp atom: HB2,TRP
referenced by chem comp atom: HB3,TRP
referenced by chem comp atom: HD1,TRP
referenced by chem comp atom: HE1,TRP
referenced by chem comp atom: HE3,TRP
referenced by chem comp atom: HZ2,TRP
referenced by chem comp atom: HZ3,TRP
referenced by chem comp atom: HH2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: C,O,TRP
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CD2,CE2,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CZ2,CH2,TRP
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CH2,HH2,TRP
referenced by entity poly seq: 1,TRP,23
referenced by entity poly seq: 1,TRP,192
referenced by entity poly seq: 1,TRP,202
referenced by entity poly seq: 1,TRP,212

TYR
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: TYR
chem comp.formula: C9 H11 N O3
chem comp.formula weight: 181.189
chem comp.mon nstd flag: y
chem comp.name: TYROSINE
chem comp.type: L-peptide linking
link to chem comp: TYR
referenced by chem comp atom: HXT,TYR
referenced by chem comp bond: OXT,HXT,TYR
referenced by entity poly seq: 1,TYR,347
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/14
referenced by chem comp atom: N,TYR
referenced by chem comp atom: CA,TYR
referenced by chem comp atom: C,TYR
referenced by chem comp atom: O,TYR
referenced by chem comp atom: CB,TYR
referenced by chem comp atom: CG,TYR
referenced by chem comp atom: CD1,TYR
referenced by chem comp atom: CD2,TYR
referenced by chem comp atom: CE1,TYR
referenced by chem comp atom: CE2,TYR
referenced by chem comp atom: CZ,TYR
referenced by chem comp atom: OH,TYR
referenced by chem comp atom: OXT,TYR
referenced by chem comp atom: H,TYR
referenced by chem comp atom: H2,TYR
referenced by chem comp atom: HA,TYR
referenced by chem comp atom: HB2,TYR
referenced by chem comp atom: HB3,TYR
referenced by chem comp atom: HD1,TYR
referenced by chem comp atom: HD2,TYR
referenced by chem comp atom: HE1,TYR
referenced by chem comp atom: HE2,TYR
referenced by chem comp atom: HH,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: C,O,TYR
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CE1,CZ,TYR
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: OH,HH,TYR
referenced by entity poly seq: 1,TYR,14
referenced by entity poly seq: 1,TYR,29
referenced by entity poly seq: 1,TYR,40
referenced by entity poly seq: 1,TYR,74
referenced by entity poly seq: 1,TYR,108
referenced by entity poly seq: 1,TYR,137
referenced by entity poly seq: 1,TYR,145
referenced by entity poly seq: 1,TYR,187
referenced by entity poly seq: 1,TYR,193
referenced by entity poly seq: 1,TYR,205
referenced by entity poly seq: 1,TYR,263
referenced by entity poly seq: 1,TYR,312
referenced by entity poly seq: 1,TYR,316
referenced by entity poly seq: 1,TYR,328

VAL
type: chem comp
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
chem comp.id: VAL
chem comp.formula: C5 H11 N O2
chem comp.formula weight: 117.146
chem comp.mon nstd flag: y
chem comp.name: VALINE
chem comp.type: L-peptide linking
link to chem comp: VAL
referenced by chem comp atom: HXT,VAL
referenced by chem comp bond: OXT,HXT,VAL
referenced by entity poly seq: 1,VAL,354
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/15
referenced by chem comp atom: N,VAL
referenced by chem comp atom: CA,VAL
referenced by chem comp atom: C,VAL
referenced by chem comp atom: O,VAL
referenced by chem comp atom: CB,VAL
referenced by chem comp atom: CG1,VAL
referenced by chem comp atom: CG2,VAL
referenced by chem comp atom: OXT,VAL
referenced by chem comp atom: H,VAL
referenced by chem comp atom: H2,VAL
referenced by chem comp atom: HA,VAL
referenced by chem comp atom: HB,VAL
referenced by chem comp atom: HG11,VAL
referenced by chem comp atom: HG12,VAL
referenced by chem comp atom: HG13,VAL
referenced by chem comp atom: HG21,VAL
referenced by chem comp atom: HG22,VAL
referenced by chem comp atom: HG23,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: C,O,VAL
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL
referenced by chem comp bond: CG2,HG23,VAL
referenced by entity poly seq: 1,VAL,25
referenced by entity poly seq: 1,VAL,35
referenced by entity poly seq: 1,VAL,43
referenced by entity poly seq: 1,VAL,55
referenced by entity poly seq: 1,VAL,57
referenced by entity poly seq: 1,VAL,88
referenced by entity poly seq: 1,VAL,94
referenced by entity poly seq: 1,VAL,107
referenced by entity poly seq: 1,VAL,110
referenced by entity poly seq: 1,VAL,122
referenced by entity poly seq: 1,VAL,132
referenced by entity poly seq: 1,VAL,163
referenced by entity poly seq: 1,VAL,188
referenced by entity poly seq: 1,VAL,209
referenced by entity poly seq: 1,VAL,214
referenced by entity poly seq: 1,VAL,244
referenced by entity poly seq: 1,VAL,278
referenced by entity poly seq: 1,VAL,287
referenced by entity poly seq: 1,VAL,295
referenced by entity poly seq: 1,VAL,324
referenced by entity poly seq: 1,VAL,350

N,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: N
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 1
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA

CA,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: CA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 2
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA

C,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: C
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 3
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: C,O,ALA

O,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: O
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 4
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ALA

CB,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: CB
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 5
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA

OXT,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: OXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 6
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ALA
referenced by chem comp bond: C,OXT,ALA

H,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: H
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 7
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ALA

H2,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: H2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 8
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ALA

HA,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: HA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 9
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ALA

HB1,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: HB1
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 10
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB1,ALA

HB2,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: HB2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 11
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ALA

HB3,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: HB3
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 12
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ALA

HXT,ALA
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
chem comp atom.atom id: HXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 13
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ALA

C4,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C4
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 14
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C4,C5,AQY
referenced by chem comp bond: C3,C4,AQY
referenced by chem comp bond: C9,C4,AQY

C5,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C5
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 15
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C5,H1,AQY
referenced by chem comp bond: C4,C5,AQY
referenced by chem comp bond: C5,C6,AQY

C6,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C6
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 16
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C6,H2,AQY
referenced by chem comp bond: C7,C6,AQY
referenced by chem comp bond: C5,C6,AQY

C7,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C7
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 17
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C7,F8,AQY
referenced by chem comp bond: C2,C7,AQY
referenced by chem comp bond: C7,C6,AQY

C13,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C13
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 18
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C13,H3,AQY
referenced by chem comp bond: C12,C13,AQY
referenced by chem comp bond: C13,C14,AQY

C17,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C17
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 19
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C17,C18,AQY
referenced by chem comp bond: C9,C17,AQY
referenced by chem comp bond: N16,C17,AQY

C20,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C20
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 20
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C20,H4,AQY
referenced by chem comp bond: C19,C20,AQY
referenced by chem comp bond: C20,N21,AQY

C22,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C22
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 21
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C22,N21,AQY
referenced by chem comp bond: C34,C22,AQY
referenced by chem comp bond: C22,N23,AQY

C24,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C24
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 22
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C24,C26,AQY
referenced by chem comp bond: O25,C24,AQY
referenced by chem comp bond: C24,N23,AQY

C26,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C26
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 23
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C26,C33,AQY
referenced by chem comp bond: C27,C26,AQY
referenced by chem comp bond: C24,C26,AQY

C28,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C28
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 24
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C28,H5,AQY
referenced by chem comp bond: C27,C28,AQY
referenced by chem comp bond: C28,N29,AQY

C1,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C1
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 25
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C1,H8,AQY
referenced by chem comp bond: C1,C2,AQY
referenced by chem comp bond: C1,H6,AQY
referenced by chem comp bond: C1,H7,AQY

C2,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C2
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 26
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C2,C7,AQY
referenced by chem comp bond: C1,C2,AQY
referenced by chem comp bond: C3,C2,AQY

C3,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C3
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 27
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C3,H9,AQY
referenced by chem comp bond: C3,C4,AQY
referenced by chem comp bond: C3,C2,AQY

F8,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: F8
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 28
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: F
referenced by chem comp bond: C7,F8,AQY

C9,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C9
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 29
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C9,C17,AQY
referenced by chem comp bond: N10,C9,AQY
referenced by chem comp bond: C9,C4,AQY

N10,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N10
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 30
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N10,C9,AQY
referenced by chem comp bond: C11,N10,AQY

C11,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C11
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 31
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C11,N16,AQY
referenced by chem comp bond: C12,C11,AQY
referenced by chem comp bond: C11,N10,AQY

C12,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C12
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 32
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C12,H10,AQY
referenced by chem comp bond: C12,C13,AQY
referenced by chem comp bond: C12,C11,AQY

C14,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C14
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 33
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C14,H11,AQY
referenced by chem comp bond: C13,C14,AQY
referenced by chem comp bond: C14,N15,AQY

N15,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N15
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 34
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N16,N15,AQY
referenced by chem comp bond: C14,N15,AQY

N16,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N16
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 35
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N16,C17,AQY
referenced by chem comp bond: C11,N16,AQY
referenced by chem comp bond: N16,N15,AQY

C18,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C18
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 36
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C18,C19,AQY
referenced by chem comp bond: C17,C18,AQY
referenced by chem comp bond: C18,C34,AQY

C19,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C19
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 37
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C19,H12,AQY
referenced by chem comp bond: C18,C19,AQY
referenced by chem comp bond: C19,C20,AQY

N21,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N21
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 38
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: C20,N21,AQY
referenced by chem comp bond: C22,N21,AQY

N23,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N23
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 39
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N23,H13,AQY
referenced by chem comp bond: C22,N23,AQY
referenced by chem comp bond: C24,N23,AQY

O25,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: O25
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 40
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O25,C24,AQY

C27,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C27
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 41
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C27,H14,AQY
referenced by chem comp bond: C27,C26,AQY
referenced by chem comp bond: C27,C28,AQY

N29,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: N29
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 42
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N29,O30,AQY
referenced by chem comp bond: C28,N29,AQY
referenced by chem comp bond: N29,C31,AQY

O30,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: O30
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 43
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: N29,O30,AQY

C31,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C31
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 44
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C31,C32,AQY
referenced by chem comp bond: N29,C31,AQY
referenced by chem comp bond: C33,C31,AQY

C32,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C32
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 45
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C32,H18,AQY
referenced by chem comp bond: C31,C32,AQY
referenced by chem comp bond: C32,H16,AQY
referenced by chem comp bond: C32,H17,AQY

C33,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C33
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 46
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C33,H19,AQY
referenced by chem comp bond: C26,C33,AQY
referenced by chem comp bond: C33,C31,AQY

C34,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: C34
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 47
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C34,H20,AQY
referenced by chem comp bond: C18,C34,AQY
referenced by chem comp bond: C34,C22,AQY

H1,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H1
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 48
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C5,H1,AQY

H2,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H2
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 49
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C6,H2,AQY

H3,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H3
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 50
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C13,H3,AQY

H4,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H4
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 51
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C20,H4,AQY

H5,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H5
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 52
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C28,H5,AQY

H6,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H6
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 53
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H6,AQY

H7,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H7
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 54
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H7,AQY

H8,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H8
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 55
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H8,AQY

H9,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H9
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 56
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C3,H9,AQY

H10,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H10
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 57
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C12,H10,AQY

H11,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H11
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 58
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C14,H11,AQY

H12,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H12
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 59
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C19,H12,AQY

H13,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H13
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 60
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N23,H13,AQY

H14,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H14
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 61
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C27,H14,AQY

H16,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H16
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 62
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C32,H16,AQY

H17,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H17
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 63
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C32,H17,AQY

H18,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H18
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 64
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C32,H18,AQY

H19,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H19
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 65
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C33,H19,AQY

H20,AQY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: AQY
chem comp atom.atom id: H20
chem comp atom.comp id: AQY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 66
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C34,H20,AQY

N,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: N
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 67
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG

CA,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: CA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 68
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG

C,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: C
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 69
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: C,O,ARG

O,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: O
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 70
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ARG

CB,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: CB
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 71
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG

CG,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: CG
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 72
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG

CD,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: CD
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 73
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG

NE,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: NE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 74
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: NE,CZ,ARG

CZ,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: CZ
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 75
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: CZ,NH1,ARG

NH1,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: NH1
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 76
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: NH1,HH11,ARG

NH2,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: NH2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 77
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH2,HH22,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH2,HH21,ARG

OXT,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: OXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 78
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ARG
referenced by chem comp bond: C,OXT,ARG

H,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: H
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 79
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ARG

H2,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: H2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 80
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ARG

HA,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 81
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ARG

HB2,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HB2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 82
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ARG

HB3,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HB3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 83
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ARG

HG2,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HG2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 84
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,ARG

HG3,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HG3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 85
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,ARG

HD2,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HD2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 86
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,ARG

HD3,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HD3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 87
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,ARG

HE,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 88
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE,HE,ARG

HH11,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HH11
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 89
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH11,ARG

HH12,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HH12
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 90
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH12,ARG

HH21,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HH21
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 91
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH21,ARG

HH22,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HH22
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 92
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH22,ARG

HXT,ARG
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
chem comp atom.atom id: HXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 93
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ARG

N,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: N
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 94
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN

CA,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: CA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 95
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN

C,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: C
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 96
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: C,O,ASN

O,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: O
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 97
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASN

CB,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: CB
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 98
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN

CG,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: CG
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 99
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CG,OD1,ASN

OD1,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: OD1
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 100
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASN

ND2,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: ND2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 101
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND2,HD22,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN

OXT,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: OXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 102
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASN
referenced by chem comp bond: C,OXT,ASN

H,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: H
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 103
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASN

H2,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: H2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 104
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASN

HA,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 105
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASN

HB2,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HB2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 106
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASN

HB3,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HB3
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 107
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASN

HD21,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HD21
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 108
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD21,ASN

HD22,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HD22
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 109
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD22,ASN

HXT,ASN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
chem comp atom.atom id: HXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 110
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASN

N,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: N
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 111
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP

CA,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: CA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 112
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP

C,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: C
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 113
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: C,O,ASP

O,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: O
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 114
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASP

CB,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: CB
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 115
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP

CG,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: CG
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 116
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CG,OD1,ASP

OD1,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: OD1
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 117
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASP

OD2,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: OD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 118
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OD2,HD2,ASP
referenced by chem comp bond: CG,OD2,ASP

OXT,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: OXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 119
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASP
referenced by chem comp bond: C,OXT,ASP

H,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: H
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 120
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASP

H2,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: H2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 121
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASP

HA,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: HA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 122
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASP

HB2,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: HB2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 123
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASP

HB3,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: HB3
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 124
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASP

HD2,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: HD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 125
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OD2,HD2,ASP

HXT,ASP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
chem comp atom.atom id: HXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 126
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASP

N,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: N
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 127
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS

CA,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: CA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 128
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS

C,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: C
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 129
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: C,O,CYS

O,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: O
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 130
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,CYS

CB,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: CB
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 131
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS

SG,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: SG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 132
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SG,HG,CYS
referenced by chem comp bond: CB,SG,CYS

OXT,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: OXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 133
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,CYS
referenced by chem comp bond: C,OXT,CYS

H,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: H
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 134
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,CYS

H2,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: H2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 135
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,CYS

HA,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: HA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 136
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,CYS

HB2,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: HB2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 137
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,CYS

HB3,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: HB3
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 138
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,CYS

HG,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: HG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 139
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: SG,HG,CYS

HXT,CYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
chem comp atom.atom id: HXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 140
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,CYS

N,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: N
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 141
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN

CA,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: CA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 142
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN

C,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: C
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 143
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: C,O,GLN

O,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: O
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 144
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLN

CB,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: CB
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 145
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN

CG,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: CG
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 146
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN

CD,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: CD
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 147
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CD,OE1,GLN

OE1,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: OE1
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 148
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLN

NE2,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: NE2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 149
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE22,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN

OXT,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: OXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 150
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLN
referenced by chem comp bond: C,OXT,GLN

H,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: H
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 151
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLN

H2,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: H2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 152
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLN

HA,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 153
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLN

HB2,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HB2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 154
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLN

HB3,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HB3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 155
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLN

HG2,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HG2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 156
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLN

HG3,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HG3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 157
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLN

HE21,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HE21
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 158
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE21,GLN

HE22,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HE22
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 159
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE22,GLN

HXT,GLN
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
chem comp atom.atom id: HXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 160
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLN

N,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: N
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 161
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU

CA,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: CA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 162
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU

C,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: C
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 163
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: C,O,GLU

O,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: O
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 164
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLU

CB,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: CB
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 165
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU

CG,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: CG
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 166
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU

CD,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: CD
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 167
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CD,OE1,GLU

OE1,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: OE1
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 168
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLU

OE2,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: OE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 169
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OE2,HE2,GLU
referenced by chem comp bond: CD,OE2,GLU

OXT,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: OXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 170
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLU
referenced by chem comp bond: C,OXT,GLU

H,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: H
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 171
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLU

H2,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: H2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 172
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLU

HA,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 173
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLU

HB2,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HB2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 174
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLU

HB3,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HB3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 175
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLU

HG2,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HG2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 176
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLU

HG3,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HG3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 177
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLU

HE2,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 178
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OE2,HE2,GLU

HXT,GLU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
chem comp atom.atom id: HXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 179
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLU

N,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: N
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 180
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY

CA,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: CA
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 181
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY

C,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: C
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 182
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: C,O,GLY

O,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: O
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 183
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLY

OXT,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: OXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 184
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLY
referenced by chem comp bond: C,OXT,GLY

H,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: H
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 185
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLY

H2,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: H2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 186
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLY

HA2,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: HA2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 187
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA2,GLY

HA3,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: HA3
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 188
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA3,GLY

HXT,GLY
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
chem comp atom.atom id: HXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 189
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLY

N,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: N
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 190
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS

CA,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: CA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 191
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS

C,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: C
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 192
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: C,O,HIS

O,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: O
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 193
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,HIS

CB,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: CB
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 194
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS

CG,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: CG
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 195
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CG,ND1,HIS

ND1,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: ND1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 196
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: ND1,CE1,HIS

CD2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: CD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 197
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CD2,NE2,HIS

CE1,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: CE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 198
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: CE1,NE2,HIS

NE2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: NE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 199
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CD2,NE2,HIS

OXT,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: OXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 200
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,HIS
referenced by chem comp bond: C,OXT,HIS

H,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: H
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 201
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,HIS

H2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: H2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 202
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,HIS

HA,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 203
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,HIS

HB2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HB2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 204
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,HIS

HB3,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HB3
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 205
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,HIS

HD1,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HD1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 206
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND1,HD1,HIS

HD2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 207
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,HIS

HE1,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 208
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,HIS

HE2,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 209
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE2,HIS

HXT,HIS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
chem comp atom.atom id: HXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 210
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,HIS

O,HOH
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HOH
chem comp atom.atom id: O
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 211
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O,H2,HOH
referenced by chem comp bond: O,H1,HOH

H1,HOH
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HOH
chem comp atom.atom id: H1
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 212
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H1,HOH

H2,HOH
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HOH
chem comp atom.atom id: H2
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 213
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H2,HOH

N,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: N
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 214
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE

CA,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: CA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 215
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE

C,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: C
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 216
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: C,O,ILE

O,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: O
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 217
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ILE

CB,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: CB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 218
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE

CG1,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: CG1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 219
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE

CG2,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: CG2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 220
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE

CD1,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: CD1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 221
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE

OXT,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: OXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 222
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ILE
referenced by chem comp bond: C,OXT,ILE

H,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: H
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 223
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ILE

H2,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: H2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 224
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ILE

HA,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 225
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ILE

HB,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 226
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,ILE

HG12,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HG12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 227
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,ILE

HG13,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HG13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 228
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,ILE

HG21,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HG21
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 229
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,ILE

HG22,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HG22
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 230
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,ILE

HG23,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HG23
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 231
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,ILE

HD11,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HD11
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 232
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,ILE

HD12,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HD12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 233
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,ILE

HD13,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HD13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 234
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,ILE

HXT,ILE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
chem comp atom.atom id: HXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 235
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ILE

N,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: N
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 236
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU

CA,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: CA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 237
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU

C,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: C
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 238
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: C,O,LEU

O,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: O
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 239
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LEU

CB,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: CB
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 240
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU

CG,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: CG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 241
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU

CD1,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: CD1
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 242
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU

CD2,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: CD2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 243
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD23,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU

OXT,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: OXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 244
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LEU
referenced by chem comp bond: C,OXT,LEU

H,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: H
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 245
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LEU

H2,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: H2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 246
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LEU

HA,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 247
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LEU

HB2,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HB2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 248
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LEU

HB3,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HB3
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 249
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LEU

HG,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 250
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG,LEU

HD11,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD11
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 251
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,LEU

HD12,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD12
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 252
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,LEU

HD13,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD13
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 253
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,LEU

HD21,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD21
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 254
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD21,LEU

HD22,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD22
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 255
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD22,LEU

HD23,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HD23
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 256
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD23,LEU

HXT,LEU
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
chem comp atom.atom id: HXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 257
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LEU

N,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: N
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 258
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS

CA,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: CA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 259
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS

C,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: C
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 260
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: C,O,LYS

O,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: O
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 261
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LYS

CB,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: CB
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 262
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS

CG,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: CG
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 263
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS

CD,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: CD
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 264
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS

CE,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: CE
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 265
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS

NZ,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: NZ
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 266
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NZ,HZ3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS

OXT,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: OXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 267
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LYS
referenced by chem comp bond: C,OXT,LYS

H,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: H
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 268
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LYS

H2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: H2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 269
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LYS

HA,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 270
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LYS

HB2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HB2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 271
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LYS

HB3,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HB3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 272
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LYS

HG2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HG2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 273
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,LYS

HG3,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HG3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 274
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,LYS

HD2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HD2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 275
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,LYS

HD3,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HD3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 276
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,LYS

HE2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HE2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 277
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,LYS

HE3,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HE3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 278
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,LYS

HZ1,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HZ1
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 279
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ1,LYS

HZ2,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HZ2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 280
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ2,LYS

HZ3,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HZ3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 281
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ3,LYS

HXT,LYS
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
chem comp atom.atom id: HXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 282
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LYS

N,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: N
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 283
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET

CA,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: CA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 284
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET

C,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: C
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 285
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: C,O,MET

O,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: O
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 286
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,MET

CB,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: CB
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 287
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET

CG,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: CG
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 288
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET

SD,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: SD
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 289
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CG,SD,MET

CE,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: CE
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 290
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET

OXT,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: OXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 291
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,MET
referenced by chem comp bond: C,OXT,MET

H,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: H
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 292
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,MET

H2,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: H2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 293
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,MET

HA,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 294
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,MET

HB2,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HB2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 295
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,MET

HB3,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HB3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 296
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,MET

HG2,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HG2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 297
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,MET

HG3,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HG3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 298
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,MET

HE1,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HE1
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 299
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE1,MET

HE2,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HE2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 300
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,MET

HE3,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HE3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 301
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,MET

HXT,MET
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
chem comp atom.atom id: HXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 302
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,MET

N,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: N
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 303
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE

CA,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 304
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE

C,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: C
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 305
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: C,O,PHE

O,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: O
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 306
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PHE

CB,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CB
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 307
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE

CG,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CG
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 308
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CG,CD1,PHE

CD1,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 309
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CD1,CE1,PHE

CD2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 310
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD2,CE2,PHE

CE1,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 311
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CE1,CZ,PHE

CE2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 312
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CE2,CZ,PHE

CZ,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: CZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 313
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,HZ,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE1,CZ,PHE

OXT,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: OXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 314
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PHE
referenced by chem comp bond: C,OXT,PHE

H,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: H
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 315
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PHE

H2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: H2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 316
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,PHE

HA,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 317
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PHE

HB2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HB2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 318
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PHE

HB3,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HB3
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 319
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PHE

HD1,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 320
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,PHE

HD2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 321
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,PHE

HE1,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 322
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,PHE

HE2,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 323
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,PHE

HZ,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 324
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ,HZ,PHE

HXT,PHE
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
chem comp atom.atom id: HXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 325
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PHE

N,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: N
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 326
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO

CA,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: CA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 327
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO

C,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: C
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 328
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: C,O,PRO

O,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: O
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 329
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PRO

CB,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: CB
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 330
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO

CG,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: CG
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 331
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO

CD,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: CD
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 332
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: CD,HD2,PRO

OXT,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: OXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 333
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PRO
referenced by chem comp bond: C,OXT,PRO

H,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: H
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 334
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PRO

HA,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 335
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PRO

HB2,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HB2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 336
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PRO

HB3,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HB3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 337
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PRO

HG2,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HG2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 338
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,PRO

HG3,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HG3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 339
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,PRO

HD2,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HD2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 340
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,PRO

HD3,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HD3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 341
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,PRO

HXT,PRO
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
chem comp atom.atom id: HXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 342
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PRO

N,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: N
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 343
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER

CA,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: CA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 344
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER

C,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: C
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 345
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: C,O,SER

O,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: O
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 346
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,SER

CB,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: CB
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 347
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER

OG,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: OG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 348
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG,HG,SER
referenced by chem comp bond: CB,OG,SER

OXT,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: OXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 349
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,SER
referenced by chem comp bond: C,OXT,SER

H,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: H
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 350
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,SER

H2,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: H2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 351
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,SER

HA,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: HA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 352
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,SER

HB2,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: HB2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 353
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,SER

HB3,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: HB3
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 354
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,SER

HG,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: HG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 355
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG,HG,SER

HXT,SER
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
chem comp atom.atom id: HXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 356
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,SER

N,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: N
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 357
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR

CA,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: CA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 358
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR

C,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: C
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 359
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: C,O,THR

O,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: O
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 360
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,THR

CB,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: CB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 361
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR

OG1,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: OG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 362
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CB,OG1,THR

CG2,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: CG2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 363
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR

OXT,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: OXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 364
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,THR
referenced by chem comp bond: C,OXT,THR

H,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: H
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 365
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,THR

H2,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: H2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 366
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,THR

HA,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 367
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,THR

HB,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 368
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,THR

HG1,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 369
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG1,HG1,THR

HG21,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HG21
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 370
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,THR

HG22,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HG22
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 371
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,THR

HG23,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HG23
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 372
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,THR

HXT,THR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
chem comp atom.atom id: HXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 373
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,THR

N,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: N
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 374
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP

CA,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 375
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP

C,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: C
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 376
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: C,O,TRP

O,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: O
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 377
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TRP

CB,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CB
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 378
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP

CG,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CG
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 379
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CG,CD1,TRP

CD1,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 380
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CD1,NE1,TRP

CD2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CD2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 381
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD2,CE2,TRP

NE1,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: NE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 382
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: NE1,CE2,TRP

CE2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CE2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 383
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: CD2,CE2,TRP

CE3,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 384
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CE3,CZ3,TRP

CZ2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 385
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

CZ3,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 386
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CZ3,CH2,TRP

CH2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: CH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 387
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CH2,HH2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

OXT,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: OXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 388
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TRP
referenced by chem comp bond: C,OXT,TRP

H,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: H
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 389
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TRP

H2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: H2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 390
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TRP

HA,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 391
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TRP

HB2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HB2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 392
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TRP

HB3,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HB3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 393
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TRP

HD1,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 394
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TRP

HE1,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 395
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE1,HE1,TRP

HE3,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 396
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE3,HE3,TRP

HZ2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 397
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ2,HZ2,TRP

HZ3,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 398
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ3,HZ3,TRP

HH2,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 399
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CH2,HH2,TRP

HXT,TRP
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
chem comp atom.atom id: HXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 400
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TRP

N,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: N
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 401
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR

CA,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 402
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR

C,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: C
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 403
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: C,O,TYR

O,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: O
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 404
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TYR

CB,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CB
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 405
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR

CG,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CG
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 406
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CG,CD1,TYR

CD1,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 407
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CD1,CE1,TYR

CD2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 408
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD2,CE2,TYR

CE1,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 409
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CE1,CZ,TYR

CE2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 410
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CE2,CZ,TYR

CZ,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: CZ
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 411
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE1,CZ,TYR

OH,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: OH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 412
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OH,HH,TYR
referenced by chem comp bond: CZ,OH,TYR

OXT,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: OXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 413
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TYR
referenced by chem comp bond: C,OXT,TYR

H,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: H
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 414
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TYR

H2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: H2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 415
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TYR

HA,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 416
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TYR

HB2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HB2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 417
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TYR

HB3,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HB3
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 418
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TYR

HD1,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 419
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TYR

HD2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 420
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,TYR

HE1,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 421
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,TYR

HE2,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 422
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,TYR

HH,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 423
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OH,HH,TYR

HXT,TYR
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
chem comp atom.atom id: HXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 424
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TYR

N,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: N
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 425
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL

CA,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: CA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 426
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL

C,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: C
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 427
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: C,O,VAL

O,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: O
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 428
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,VAL

CB,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: CB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 429
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL

CG1,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: CG1
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 430
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL

CG2,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: CG2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 431
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL

OXT,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: OXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 432
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,VAL
referenced by chem comp bond: C,OXT,VAL

H,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: H
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 433
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,VAL

H2,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: H2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 434
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,VAL

HA,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 435
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,VAL

HB,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 436
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,VAL

HG11,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG11
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 437
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG11,VAL

HG12,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG12
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 438
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,VAL

HG13,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG13
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 439
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,VAL

HG21,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG21
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 440
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,VAL

HG22,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG22
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 441
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,VAL

HG23,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HG23
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 442
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,VAL

HXT,VAL
type: chem comp atom
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
chem comp atom.atom id: HXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 443
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,VAL

N,CA,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ALA
reference to chem comp atom: CA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 1
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ALA
reference to chem comp atom: H,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 2
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ALA
reference to chem comp atom: H2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 3
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ALA
reference to chem comp atom: C,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 4
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ALA
reference to chem comp atom: CB,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 5
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ALA
reference to chem comp atom: HA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 6
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ALA
reference to chem comp atom: O,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 7
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ALA
reference to chem comp atom: OXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 8
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB1,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB1,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB1
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 9
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 10
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB3,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 11
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ALA
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,ALA
reference to chem comp atom: HXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 12
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C12,C13,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C12,AQY
reference to chem comp atom: C13,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: C13
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 13
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C12,C11,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C12,AQY
reference to chem comp atom: C11,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: C11
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 14
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C13,C14,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C13,AQY
reference to chem comp atom: C14,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C13
chem comp bond.atom id 2: C14
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 15
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C11,N10,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C11,AQY
reference to chem comp atom: N10,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C11
chem comp bond.atom id 2: N10
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 16
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C11,N16,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C11,AQY
reference to chem comp atom: N16,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C11
chem comp bond.atom id 2: N16
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 17
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C14,N15,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C14,AQY
reference to chem comp atom: N15,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C14
chem comp bond.atom id 2: N15
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 18
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N10,C9,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N10,AQY
reference to chem comp atom: C9,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N10
chem comp bond.atom id 2: C9
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 19
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N16,N15,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N16,AQY
reference to chem comp atom: N15,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N16
chem comp bond.atom id 2: N15
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 20
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N16,C17,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N16,AQY
reference to chem comp atom: C17,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N16
chem comp bond.atom id 2: C17
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 21
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C9,C4,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C9,AQY
reference to chem comp atom: C4,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C9
chem comp bond.atom id 2: C4
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 22
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C9,C17,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C9,AQY
reference to chem comp atom: C17,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C9
chem comp bond.atom id 2: C17
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 23
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C3,C4,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C3,AQY
reference to chem comp atom: C4,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: C4
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 24
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C3,C2,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C3,AQY
reference to chem comp atom: C2,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: C2
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 25
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,C2,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C1,AQY
reference to chem comp atom: C2,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: C2
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 26
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C4,C5,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C4,AQY
reference to chem comp atom: C5,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: C5
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 27
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C17,C18,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C17,AQY
reference to chem comp atom: C18,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C17
chem comp bond.atom id 2: C18
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 28
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,C7,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C2,AQY
reference to chem comp atom: C7,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: C7
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 29
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C5,C6,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C5,AQY
reference to chem comp atom: C6,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: C6
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 30
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C7,C6,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C7,AQY
reference to chem comp atom: C6,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C7
chem comp bond.atom id 2: C6
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 31
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C7,F8,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C7,AQY
reference to chem comp atom: F8,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C7
chem comp bond.atom id 2: F8
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 32
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C18,C34,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C18,AQY
reference to chem comp atom: C34,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C18
chem comp bond.atom id 2: C34
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 33
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C18,C19,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C18,AQY
reference to chem comp atom: C19,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C18
chem comp bond.atom id 2: C19
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 34
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C34,C22,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C34,AQY
reference to chem comp atom: C22,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C34
chem comp bond.atom id 2: C22
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 35
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O25,C24,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: O25,AQY
reference to chem comp atom: C24,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: O25
chem comp bond.atom id 2: C24
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 36
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C19,C20,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C19,AQY
reference to chem comp atom: C20,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C19
chem comp bond.atom id 2: C20
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 37
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C24,N23,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C24,AQY
reference to chem comp atom: N23,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C24
chem comp bond.atom id 2: N23
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 38
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C24,C26,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C24,AQY
reference to chem comp atom: C26,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C24
chem comp bond.atom id 2: C26
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 39
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C22,N23,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C22,AQY
reference to chem comp atom: N23,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C22
chem comp bond.atom id 2: N23
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 40
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C22,N21,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C22,AQY
reference to chem comp atom: N21,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C22
chem comp bond.atom id 2: N21
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 41
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C27,C26,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C27,AQY
reference to chem comp atom: C26,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C27
chem comp bond.atom id 2: C26
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 42
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C27,C28,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C27,AQY
reference to chem comp atom: C28,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C27
chem comp bond.atom id 2: C28
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 43
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C20,N21,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C20,AQY
reference to chem comp atom: N21,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C20
chem comp bond.atom id 2: N21
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 44
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C26,C33,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C26,AQY
reference to chem comp atom: C33,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C26
chem comp bond.atom id 2: C33
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 45
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C28,N29,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C28,AQY
reference to chem comp atom: N29,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C28
chem comp bond.atom id 2: N29
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 46
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C33,C31,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C33,AQY
reference to chem comp atom: C31,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C33
chem comp bond.atom id 2: C31
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 47
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N29,C31,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N29,AQY
reference to chem comp atom: C31,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N29
chem comp bond.atom id 2: C31
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 48
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N29,O30,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N29,AQY
reference to chem comp atom: O30,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N29
chem comp bond.atom id 2: O30
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 49
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C31,C32,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C31,AQY
reference to chem comp atom: C32,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C31
chem comp bond.atom id 2: C32
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 50
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C5,H1,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C5,AQY
reference to chem comp atom: H1,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: H1
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 51
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C6,H2,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C6,AQY
reference to chem comp atom: H2,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C6
chem comp bond.atom id 2: H2
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 52
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C13,H3,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C13,AQY
reference to chem comp atom: H3,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C13
chem comp bond.atom id 2: H3
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 53
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C20,H4,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C20,AQY
reference to chem comp atom: H4,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C20
chem comp bond.atom id 2: H4
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 54
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C28,H5,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C28,AQY
reference to chem comp atom: H5,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C28
chem comp bond.atom id 2: H5
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 55
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H6,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C1,AQY
reference to chem comp atom: H6,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H6
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 56
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H7,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C1,AQY
reference to chem comp atom: H7,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H7
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 57
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H8,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C1,AQY
reference to chem comp atom: H8,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H8
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 58
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,H9,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C3,AQY
reference to chem comp atom: H9,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: H9
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 59
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C12,H10,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C12,AQY
reference to chem comp atom: H10,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: H10
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 60
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C14,H11,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C14,AQY
reference to chem comp atom: H11,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C14
chem comp bond.atom id 2: H11
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 61
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C19,H12,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C19,AQY
reference to chem comp atom: H12,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C19
chem comp bond.atom id 2: H12
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 62
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N23,H13,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N23,AQY
reference to chem comp atom: H13,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: N23
chem comp bond.atom id 2: H13
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 63
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C27,H14,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C27,AQY
reference to chem comp atom: H14,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C27
chem comp bond.atom id 2: H14
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 64
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C32,H16,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C32,AQY
reference to chem comp atom: H16,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C32
chem comp bond.atom id 2: H16
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 65
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C32,H17,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C32,AQY
reference to chem comp atom: H17,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C32
chem comp bond.atom id 2: H17
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 66
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C32,H18,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C32,AQY
reference to chem comp atom: H18,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C32
chem comp bond.atom id 2: H18
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 67
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C33,H19,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C33,AQY
reference to chem comp atom: H19,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C33
chem comp bond.atom id 2: H19
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 68
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C34,H20,AQY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C34,AQY
reference to chem comp atom: H20,AQY
reference to chem comp: AQY
chem comp bond.atom id 1: C34
chem comp bond.atom id 2: H20
chem comp bond.comp id: AQY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 69
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ARG
reference to chem comp atom: CA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 70
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ARG
reference to chem comp atom: H,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 71
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ARG
reference to chem comp atom: H2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 72
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ARG
reference to chem comp atom: C,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 73
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ARG
reference to chem comp atom: CB,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 74
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ARG
reference to chem comp atom: HA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 75
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ARG
reference to chem comp atom: O,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 76
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ARG
reference to chem comp atom: OXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 77
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ARG
reference to chem comp atom: CG,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 78
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 79
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 80
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ARG
reference to chem comp atom: CD,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 81
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 82
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 83
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,NE,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,ARG
reference to chem comp atom: NE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 84
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 85
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 86
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,CZ,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE,ARG
reference to chem comp atom: CZ,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: CZ
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 87
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,HE,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE,ARG
reference to chem comp atom: HE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: HE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 88
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH1,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH1,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH1
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 89
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH2,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 90
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

NH1,HH11,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH11,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH11
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 91
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH1,HH12,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH12,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH12
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 92
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH21,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH21,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH21
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 93
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH22,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH22,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH22
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 94
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ARG
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,ARG
reference to chem comp atom: HXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 95
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASN
reference to chem comp atom: CA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 96
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASN
reference to chem comp atom: H,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 97
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASN
reference to chem comp atom: H2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 98
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASN
reference to chem comp atom: C,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 99
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASN
reference to chem comp atom: CB,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 100
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASN
reference to chem comp atom: HA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 101
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ASN
reference to chem comp atom: O,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 102
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ASN
reference to chem comp atom: OXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 103
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASN
reference to chem comp atom: CG,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 104
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 105
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB3,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 106
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ASN
reference to chem comp atom: OD1,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 107
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,ND2,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ASN
reference to chem comp atom: ND2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 108
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD21,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD21,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 109
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD22,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD22,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 110
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,ASN
reference to chem comp atom: HXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 111
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASP
reference to chem comp atom: CA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 112
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASP
reference to chem comp atom: H,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 113
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ASP
reference to chem comp atom: H2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 114
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASP
reference to chem comp atom: C,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 115
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASP
reference to chem comp atom: CB,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 116
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ASP
reference to chem comp atom: HA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 117
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ASP
reference to chem comp atom: O,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 118
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ASP
reference to chem comp atom: OXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 119
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASP
reference to chem comp atom: CG,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 120
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 121
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB3,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 122
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD1,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 123
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,OD2,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 124
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OD2,HD2,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OD2,ASP
reference to chem comp atom: HD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 125
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,ASP
reference to chem comp atom: HXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 126
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,CYS
reference to chem comp atom: CA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 127
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,CYS
reference to chem comp atom: H,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 128
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,CYS
reference to chem comp atom: H2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 129
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,CYS
reference to chem comp atom: C,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 130
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,CYS
reference to chem comp atom: CB,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 131
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,CYS
reference to chem comp atom: HA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 132
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,CYS
reference to chem comp atom: O,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 133
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,CYS
reference to chem comp atom: OXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 134
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,SG,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,CYS
reference to chem comp atom: SG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: SG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 135
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 136
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB3,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 137
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SG,HG,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: SG,CYS
reference to chem comp atom: HG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: SG
chem comp bond.atom id 2: HG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 138
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,CYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,CYS
reference to chem comp atom: HXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 139
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLN
reference to chem comp atom: CA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 140
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLN
reference to chem comp atom: H,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 141
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLN
reference to chem comp atom: H2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 142
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLN
reference to chem comp atom: C,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 143
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLN
reference to chem comp atom: CB,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 144
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLN
reference to chem comp atom: HA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 145
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLN
reference to chem comp atom: O,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 146
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLN
reference to chem comp atom: OXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 147
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLN
reference to chem comp atom: CG,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 148
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 149
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 150
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLN
reference to chem comp atom: CD,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 151
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 152
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 153
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,GLN
reference to chem comp atom: OE1,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 154
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,NE2,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,GLN
reference to chem comp atom: NE2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 155
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE21,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE21,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE21
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 156
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE22,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE22,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE22
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 157
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLN
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,GLN
reference to chem comp atom: HXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 158
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLU
reference to chem comp atom: CA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 159
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLU
reference to chem comp atom: H,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 160
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLU
reference to chem comp atom: H2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 161
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLU
reference to chem comp atom: C,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 162
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLU
reference to chem comp atom: CB,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 163
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLU
reference to chem comp atom: HA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 164
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLU
reference to chem comp atom: O,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 165
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLU
reference to chem comp atom: OXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 166
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLU
reference to chem comp atom: CG,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 167
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 168
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 169
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLU
reference to chem comp atom: CD,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 170
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 171
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 172
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE1,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 173
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,OE2,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 174
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OE2,HE2,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OE2,GLU
reference to chem comp atom: HE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 175
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,GLU
reference to chem comp atom: HXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 176
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLY
reference to chem comp atom: CA,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 177
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLY
reference to chem comp atom: H,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 178
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,GLY
reference to chem comp atom: H2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 179
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLY
reference to chem comp atom: C,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 180
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA2,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 181
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA3,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA3,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA3
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 182
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLY
reference to chem comp atom: O,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 183
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,GLY
reference to chem comp atom: OXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 184
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLY
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,GLY
reference to chem comp atom: HXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 185
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,HIS
reference to chem comp atom: CA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 186
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,HIS
reference to chem comp atom: H,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 187
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,HIS
reference to chem comp atom: H2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 188
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,HIS
reference to chem comp atom: C,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 189
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,HIS
reference to chem comp atom: CB,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 190
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,HIS
reference to chem comp atom: HA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 191
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,HIS
reference to chem comp atom: O,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 192
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,HIS
reference to chem comp atom: OXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 193
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,HIS
reference to chem comp atom: CG,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 194
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 195
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB3,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 196
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,ND1,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,HIS
reference to chem comp atom: ND1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 197
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,HIS
reference to chem comp atom: CD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 198
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,CE1,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: ND1,HIS
reference to chem comp atom: CE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 199
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,HD1,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: ND1,HIS
reference to chem comp atom: HD1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 200
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,NE2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 201
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,HIS
reference to chem comp atom: HD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 202
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,NE2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 203
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,HE1,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,HIS
reference to chem comp atom: HE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 204
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE2,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE2,HIS
reference to chem comp atom: HE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 205
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,HIS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,HIS
reference to chem comp atom: HXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 206
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H1,HOH
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: O,HOH
reference to chem comp atom: H1,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H1
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 207
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H2,HOH
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: O,HOH
reference to chem comp atom: H2,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H2
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 208
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ILE
reference to chem comp atom: CA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 209
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ILE
reference to chem comp atom: H,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 210
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,ILE
reference to chem comp atom: H2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 211
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ILE
reference to chem comp atom: C,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 212
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ILE
reference to chem comp atom: CB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 213
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,ILE
reference to chem comp atom: HA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 214
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ILE
reference to chem comp atom: O,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 215
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,ILE
reference to chem comp atom: OXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 216
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 217
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 218
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,ILE
reference to chem comp atom: HB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 219
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,CD1,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,ILE
reference to chem comp atom: CD1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: CD1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 220
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 221
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 222
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG21,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 223
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG22,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 224
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG23,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 225
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD11,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 226
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 227
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 228
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ILE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,ILE
reference to chem comp atom: HXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 229
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LEU
reference to chem comp atom: CA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 230
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LEU
reference to chem comp atom: H,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 231
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LEU
reference to chem comp atom: H2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 232
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LEU
reference to chem comp atom: C,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 233
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LEU
reference to chem comp atom: CB,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 234
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LEU
reference to chem comp atom: HA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 235
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,LEU
reference to chem comp atom: O,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 236
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,LEU
reference to chem comp atom: OXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 237
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LEU
reference to chem comp atom: CG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 238
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 239
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB3,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 240
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD1,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 241
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 242
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LEU
reference to chem comp atom: HG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 243
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD11,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 244
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD12,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 245
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD13,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 246
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD21,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD21,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 247
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD22,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD22,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 248
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD23,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD23,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD23
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 249
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LEU
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,LEU
reference to chem comp atom: HXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 250
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LYS
reference to chem comp atom: CA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 251
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LYS
reference to chem comp atom: H,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 252
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,LYS
reference to chem comp atom: H2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 253
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LYS
reference to chem comp atom: C,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 254
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LYS
reference to chem comp atom: CB,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 255
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,LYS
reference to chem comp atom: HA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 256
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,LYS
reference to chem comp atom: O,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 257
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,LYS
reference to chem comp atom: OXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 258
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LYS
reference to chem comp atom: CG,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 259
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 260
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 261
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LYS
reference to chem comp atom: CD,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 262
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 263
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 264
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,CE,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,LYS
reference to chem comp atom: CE,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: CE
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 265
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 266
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 267
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,NZ,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,LYS
reference to chem comp atom: NZ,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: NZ
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 268
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 269
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 270
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ1,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ1,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ1
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 271
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ2,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 272
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ3,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 273
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LYS
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,LYS
reference to chem comp atom: HXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 274
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,MET
reference to chem comp atom: CA,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 275
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,MET
reference to chem comp atom: H,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 276
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,MET
reference to chem comp atom: H2,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 277
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,MET
reference to chem comp atom: C,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 278
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,MET
reference to chem comp atom: CB,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 279
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,MET
reference to chem comp atom: HA,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 280
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,MET
reference to chem comp atom: O,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 281
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,MET
reference to chem comp atom: OXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 282
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,MET
reference to chem comp atom: CG,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 283
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,MET
reference to chem comp atom: HB2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 284
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,MET
reference to chem comp atom: HB3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 285
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,SD,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,MET
reference to chem comp atom: SD,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: SD
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 286
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,MET
reference to chem comp atom: HG2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 287
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,MET
reference to chem comp atom: HG3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 288
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SD,CE,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: SD,MET
reference to chem comp atom: CE,MET
reference to chem comp: MET
chem comp bond.atom id 1: SD
chem comp bond.atom id 2: CE
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 289
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE1,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,MET
reference to chem comp atom: HE1,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE1
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 290
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,MET
reference to chem comp atom: HE2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 291
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE,MET
reference to chem comp atom: HE3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 292
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,MET
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,MET
reference to chem comp atom: HXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 293
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PHE
reference to chem comp atom: CA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 294
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PHE
reference to chem comp atom: H,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 295
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PHE
reference to chem comp atom: H2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 296
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PHE
reference to chem comp atom: C,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 297
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PHE
reference to chem comp atom: CB,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 298
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PHE
reference to chem comp atom: HA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 299
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,PHE
reference to chem comp atom: O,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 300
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,PHE
reference to chem comp atom: OXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 301
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PHE
reference to chem comp atom: CG,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 302
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 303
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB3,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 304
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 305
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 306
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,PHE
reference to chem comp atom: CE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 307
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,PHE
reference to chem comp atom: HD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 308
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,PHE
reference to chem comp atom: CE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 309
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,PHE
reference to chem comp atom: HD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 310
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 311
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,PHE
reference to chem comp atom: HE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 312
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE2,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 313
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE2,PHE
reference to chem comp atom: HE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 314
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,HZ,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ,PHE
reference to chem comp atom: HZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: HZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 315
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PHE
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,PHE
reference to chem comp atom: HXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 316
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PRO
reference to chem comp atom: CA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 317
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CD,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 318
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,PRO
reference to chem comp atom: H,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 319
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PRO
reference to chem comp atom: C,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 320
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PRO
reference to chem comp atom: CB,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 321
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,PRO
reference to chem comp atom: HA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 322
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,PRO
reference to chem comp atom: O,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 323
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,PRO
reference to chem comp atom: OXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 324
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PRO
reference to chem comp atom: CG,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 325
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 326
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 327
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 328
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 329
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 330
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 331
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 332
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PRO
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,PRO
reference to chem comp atom: HXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 333
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,SER
reference to chem comp atom: CA,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 334
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,SER
reference to chem comp atom: H,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 335
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,SER
reference to chem comp atom: H2,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 336
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,SER
reference to chem comp atom: C,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 337
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,SER
reference to chem comp atom: CB,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 338
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,SER
reference to chem comp atom: HA,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 339
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,SER
reference to chem comp atom: O,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 340
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,SER
reference to chem comp atom: OXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 341
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,SER
reference to chem comp atom: OG,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 342
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,SER
reference to chem comp atom: HB2,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 343
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,SER
reference to chem comp atom: HB3,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 344
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG,HG,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OG,SER
reference to chem comp atom: HG,SER
reference to chem comp: SER
chem comp bond.atom id 1: OG
chem comp bond.atom id 2: HG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 345
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,SER
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,SER
reference to chem comp atom: HXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 346
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,THR
reference to chem comp atom: CA,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 347
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,THR
reference to chem comp atom: H,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 348
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,THR
reference to chem comp atom: H2,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 349
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,THR
reference to chem comp atom: C,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 350
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,THR
reference to chem comp atom: CB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 351
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,THR
reference to chem comp atom: HA,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 352
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,THR
reference to chem comp atom: O,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 353
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,THR
reference to chem comp atom: OXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 354
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG1,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,THR
reference to chem comp atom: OG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 355
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,THR
reference to chem comp atom: CG2,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 356
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,THR
reference to chem comp atom: HB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 357
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG1,HG1,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OG1,THR
reference to chem comp atom: HG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: OG1
chem comp bond.atom id 2: HG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 358
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG21,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 359
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG22,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 360
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG23,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 361
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,THR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,THR
reference to chem comp atom: HXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 362
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TRP
reference to chem comp atom: CA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 363
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TRP
reference to chem comp atom: H,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 364
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TRP
reference to chem comp atom: H2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 365
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TRP
reference to chem comp atom: C,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 366
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TRP
reference to chem comp atom: CB,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 367
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TRP
reference to chem comp atom: HA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 368
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,TRP
reference to chem comp atom: O,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 369
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,TRP
reference to chem comp atom: OXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 370
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TRP
reference to chem comp atom: CG,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 371
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 372
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 373
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 374
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 375
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,NE1,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,TRP
reference to chem comp atom: NE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: NE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 376
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,TRP
reference to chem comp atom: HD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 377
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 378
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,CE3,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 379
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,CE2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE1,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 380
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,HE1,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: NE1,TRP
reference to chem comp atom: HE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 381
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE2,TRP
reference to chem comp atom: CZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 382
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE3,CZ3,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE3,TRP
reference to chem comp atom: CZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: CZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 383
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE3,HE3,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE3,TRP
reference to chem comp atom: HE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: HE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 384
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ2,CH2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 385
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CZ2,HZ2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: HZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 386
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,CH2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 387
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,HZ3,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: HZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 388
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CH2,HH2,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CH2,TRP
reference to chem comp atom: HH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CH2
chem comp bond.atom id 2: HH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 389
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TRP
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,TRP
reference to chem comp atom: HXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 390
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TYR
reference to chem comp atom: CA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 391
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TYR
reference to chem comp atom: H,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 392
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,TYR
reference to chem comp atom: H2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 393
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TYR
reference to chem comp atom: C,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 394
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TYR
reference to chem comp atom: CB,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 395
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,TYR
reference to chem comp atom: HA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 396
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,TYR
reference to chem comp atom: O,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 397
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,TYR
reference to chem comp atom: OXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 398
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TYR
reference to chem comp atom: CG,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 399
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 400
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB3,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 401
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 402
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 403
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,TYR
reference to chem comp atom: CE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 404
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD1,TYR
reference to chem comp atom: HD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 405
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,TYR
reference to chem comp atom: CE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 406
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CD2,TYR
reference to chem comp atom: HD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 407
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 408
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE1,TYR
reference to chem comp atom: HE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 409
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE2,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 410
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CE2,TYR
reference to chem comp atom: HE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 411
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,OH,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CZ,TYR
reference to chem comp atom: OH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: OH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 412
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OH,HH,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OH,TYR
reference to chem comp atom: HH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OH
chem comp bond.atom id 2: HH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 413
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TYR
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,TYR
reference to chem comp atom: HXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 414
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,VAL
reference to chem comp atom: CA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 415
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,VAL
reference to chem comp atom: H,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 416
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: N,VAL
reference to chem comp atom: H2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 417
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,VAL
reference to chem comp atom: C,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 418
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,VAL
reference to chem comp atom: CB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 419
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CA,VAL
reference to chem comp atom: HA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 420
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,VAL
reference to chem comp atom: O,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 421
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: C,VAL
reference to chem comp atom: OXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 422
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG1,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 423
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 424
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CB,VAL
reference to chem comp atom: HB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 425
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG11,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG11,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG11
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 426
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG12,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 427
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG13,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 428
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG21,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 429
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG22,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 430
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG23,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 431
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,VAL
type: chem comp bond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp atom: OXT,VAL
reference to chem comp atom: HXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 432
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

primary
type: citation
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
citation.id: primary
citation.country: UK
citation.journal abbrev: Bioorg. Med. Chem.
citation.journal id ASTM: BMECEP
citation.journal id CSD: 1200
citation.journal id ISSN: 1464-3391
citation.journal volume: 26
citation.page first: 647
citation.page last: 660
citation.pdbx database id DOI: 10.1016/j.bmc.2017.12.031
citation.pdbx database id pub med: 29291937
citation.title: Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
citation.year: 2018
link to doi: doi:10.1016/j.bmc.2017.12.031
link to pubmed: pubmed:29291937
references: pubmed:29291937
referenced by citation author: primary,Miwatashi, S.,19
referenced by citation author: primary,Kaieda, A.,1
referenced by citation author: primary,Takahashi, M.,2
referenced by citation author: primary,Takai, T.,3
referenced by citation author: primary,Goto, M.,4
referenced by citation author: primary,Miyazaki, T.,5
referenced by citation author: primary,Hori, Y.,6
referenced by citation author: primary,Unno, S.,7
referenced by citation author: primary,Kawamoto, T.,8
referenced by citation author: primary,Tanaka, T.,9
referenced by citation author: primary,Itono, S.,10
referenced by citation author: primary,Takagi, T.,11
referenced by citation author: primary,Hamada, T.,12
referenced by citation author: primary,Shirasaki, M.,13
referenced by citation author: primary,Okada, K.,14
referenced by citation author: primary,Snell, G.,15
referenced by citation author: primary,Bragstad, K.,16
referenced by citation author: primary,Sang, B.C.,17
referenced by citation author: primary,Uchikawa, O.,18

primary,Kaieda, A.,1
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Kaieda, A.
citation author.ordinal: 1

primary,Takahashi, M.,2
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Takahashi, M.
citation author.ordinal: 2

primary,Takai, T.,3
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Takai, T.
citation author.ordinal: 3

primary,Goto, M.,4
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Goto, M.
citation author.ordinal: 4

primary,Miyazaki, T.,5
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Miyazaki, T.
citation author.ordinal: 5

primary,Hori, Y.,6
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Hori, Y.
citation author.ordinal: 6

primary,Unno, S.,7
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Unno, S.
citation author.ordinal: 7

primary,Kawamoto, T.,8
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Kawamoto, T.
citation author.ordinal: 8

primary,Tanaka, T.,9
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Tanaka, T.
citation author.ordinal: 9

primary,Itono, S.,10
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Itono, S.
citation author.ordinal: 10

primary,Takagi, T.,11
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Takagi, T.
citation author.ordinal: 11

primary,Hamada, T.,12
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Hamada, T.
citation author.ordinal: 12

primary,Shirasaki, M.,13
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Shirasaki, M.
citation author.ordinal: 13

primary,Okada, K.,14
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Okada, K.
citation author.ordinal: 14

primary,Snell, G.,15
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Snell, G.
citation author.ordinal: 15

primary,Bragstad, K.,16
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Bragstad, K.
citation author.ordinal: 16

primary,Sang, B.C.,17
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Sang, B.C.
citation author.ordinal: 17

primary,Uchikawa, O.,18
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Uchikawa, O.
citation author.ordinal: 18

primary,Miwatashi, S.,19
type: citation author
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to citation: primary
citation author.citation id: primary
citation author.name: Miwatashi, S.
citation author.ordinal: 19

5WJJ,PDB
type: database 2
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
database 2.database code: 5WJJ
database 2.database id: PDB
database 2.pdbx DOI: 10.2210/pdb5wjj/pdb
database 2.pdbx database accession: pdb_00005wjj

D 1000229122,WWPDB
type: database 2
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
database 2.database code: D_1000229122
database 2.database id: WWPDB

http://rdf.wwpdb.org/pdb/5WJJ/diffrn/1
type: diffrn
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to exptl crystal: http://rdf.wwpdb.org/pdb/5WJJ/exptl_crystal/1
diffrn.id: 1
diffrn.ambient temp: 100
diffrn.crystal id: 1
referenced by diffrn detector: http://rdf.wwpdb.org/pdb/5WJJ/diffrn_detector/1
referenced by diffrn radiation: http://rdf.wwpdb.org/pdb/5WJJ/diffrn_radiation/1
referenced by diffrn source: http://rdf.wwpdb.org/pdb/5WJJ/diffrn_source/1

http://rdf.wwpdb.org/pdb/5WJJ/exptl_crystal/1
referenced by diffrn: http://rdf.wwpdb.org/pdb/5WJJ/diffrn/1
type: exptl crystal
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
exptl crystal.id: 1
exptl crystal.density matthews: 2.16
exptl crystal.density percent sol: 43.13
exptl crystal.pdbx mosaicity: 0.291
referenced by exptl crystal grow: http://rdf.wwpdb.org/pdb/5WJJ/exptl_crystal_grow/1

http://rdf.wwpdb.org/pdb/5WJJ/diffrn_detector/1
type: diffrn detector
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to diffrn: http://rdf.wwpdb.org/pdb/5WJJ/diffrn/1
diffrn detector.diffrn id: 1
diffrn detector.detector: CCD
diffrn detector.pdbx collection date: 2007-05-11
diffrn detector.type: ADSC QUANTUM 315r

http://rdf.wwpdb.org/pdb/5WJJ/diffrn_radiation/1
type: diffrn radiation
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to diffrn: http://rdf.wwpdb.org/pdb/5WJJ/diffrn/1
diffrn radiation.diffrn id: 1
diffrn radiation.monochromator: Si(220)
diffrn radiation.pdbx diffrn protocol: SINGLE WAVELENGTH
diffrn radiation.pdbx monochromatic or laue m l: M
diffrn radiation.pdbx scattering type: x-ray
diffrn radiation.wavelength id: 1

http://rdf.wwpdb.org/pdb/5WJJ/diffrn_radiation_wavelength/1
type: diffrn radiation wavelength
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
diffrn radiation wavelength.id: 1
diffrn radiation wavelength.wavelength: 0.97
diffrn radiation wavelength.wt: 1

http://rdf.wwpdb.org/pdb/5WJJ/diffrn_source/1
type: diffrn source
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to diffrn: http://rdf.wwpdb.org/pdb/5WJJ/diffrn/1
diffrn source.diffrn id: 1
diffrn source.pdbx synchrotron beamline: 5.0.3
diffrn source.pdbx synchrotron site: ALS
diffrn source.pdbx wavelength list: 0.9700
diffrn source.source: SYNCHROTRON
diffrn source.type: ALS BEAMLINE 5.0.3

http://rdf.wwpdb.org/pdb/5WJJ/entity/1
type: entity
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
entity.id: 1
entity.formula weight: 41714.52
entity.pdbx description: Mitogen-activated protein kinase 14
entity.pdbx ec: 2.7.11.24
entity.pdbx number of molecules: 1
entity.src method: man
entity.type: polymer
link to enzyme: enzyme:2.7.11.24
referenced by entity name com: http://rdf.wwpdb.org/pdb/5WJJ/entity_name_com/1
referenced by entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
referenced by struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
referenced by struct ref: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref/1
referenced by entity src gen: 1,1

ec-code:2.7.11.24

http://rdf.wwpdb.org/pdb/5WJJ/entity/2
type: entity
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
entity.id: 2
entity.formula weight: 454.456
entity.pdbx description: N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide
entity.pdbx number of molecules: 1
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/B
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_entity_nonpoly/2

http://rdf.wwpdb.org/pdb/5WJJ/entity/3
type: entity
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
entity.id: 3
entity.formula weight: 18.015
entity.pdbx description: water
entity.pdbx number of molecules: 380
entity.src method: nat
entity.type: water
referenced by struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/C
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_entity_nonpoly/3

http://rdf.wwpdb.org/pdb/5WJJ/entity_name_com/1
type: entity name com
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/1
entity name com.entity id: 1
entity name com.name: MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a

http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
type: entity poly
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/1
entity poly.entity id: 1
entity poly.nstd linkage: no
entity poly.nstd monomer: no
entity poly.pdbx seq one letter code: GAMGSMSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKSQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSN LAVNEDSELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLI LRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD DEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
entity poly.pdbx seq one letter code can: GAMGSMSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLL KHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKSQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSN LAVNEDSELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLI LRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD DEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
entity poly.pdbx strand id: A
entity poly.type: polypeptide(L)
referenced by entity poly seq: 1,SER,365
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,ALA,2
referenced by entity poly seq: 1,MET,3
referenced by entity poly seq: 1,GLY,4
referenced by entity poly seq: 1,SER,5
referenced by entity poly seq: 1,MET,6
referenced by entity poly seq: 1,SER,7
referenced by entity poly seq: 1,GLN,8
referenced by entity poly seq: 1,GLU,9
referenced by entity poly seq: 1,ARG,10
referenced by entity poly seq: 1,PRO,11
referenced by entity poly seq: 1,THR,12
referenced by entity poly seq: 1,PHE,13
referenced by entity poly seq: 1,TYR,14
referenced by entity poly seq: 1,ARG,15
referenced by entity poly seq: 1,GLN,16
referenced by entity poly seq: 1,GLU,17
referenced by entity poly seq: 1,LEU,18
referenced by entity poly seq: 1,ASN,19
referenced by entity poly seq: 1,LYS,20
referenced by entity poly seq: 1,THR,21
referenced by entity poly seq: 1,ILE,22
referenced by entity poly seq: 1,TRP,23
referenced by entity poly seq: 1,GLU,24
referenced by entity poly seq: 1,VAL,25
referenced by entity poly seq: 1,PRO,26
referenced by entity poly seq: 1,GLU,27
referenced by entity poly seq: 1,ARG,28
referenced by entity poly seq: 1,TYR,29
referenced by entity poly seq: 1,GLN,30
referenced by entity poly seq: 1,ASN,31
referenced by entity poly seq: 1,LEU,32
referenced by entity poly seq: 1,SER,33
referenced by entity poly seq: 1,PRO,34
referenced by entity poly seq: 1,VAL,35
referenced by entity poly seq: 1,GLY,36
referenced by entity poly seq: 1,SER,37
referenced by entity poly seq: 1,GLY,38
referenced by entity poly seq: 1,ALA,39
referenced by entity poly seq: 1,TYR,40
referenced by entity poly seq: 1,GLY,41
referenced by entity poly seq: 1,SER,42
referenced by entity poly seq: 1,VAL,43
referenced by entity poly seq: 1,CYS,44
referenced by entity poly seq: 1,ALA,45
referenced by entity poly seq: 1,ALA,46
referenced by entity poly seq: 1,PHE,47
referenced by entity poly seq: 1,ASP,48
referenced by entity poly seq: 1,THR,49
referenced by entity poly seq: 1,LYS,50
referenced by entity poly seq: 1,THR,51
referenced by entity poly seq: 1,GLY,52
referenced by entity poly seq: 1,LEU,53
referenced by entity poly seq: 1,ARG,54
referenced by entity poly seq: 1,VAL,55
referenced by entity poly seq: 1,ALA,56
referenced by entity poly seq: 1,VAL,57
referenced by entity poly seq: 1,LYS,58
referenced by entity poly seq: 1,LYS,59
referenced by entity poly seq: 1,LEU,60
referenced by entity poly seq: 1,SER,61
referenced by entity poly seq: 1,ARG,62
referenced by entity poly seq: 1,PRO,63
referenced by entity poly seq: 1,PHE,64
referenced by entity poly seq: 1,GLN,65
referenced by entity poly seq: 1,SER,66
referenced by entity poly seq: 1,ILE,67
referenced by entity poly seq: 1,ILE,68
referenced by entity poly seq: 1,HIS,69

1,GLY,1
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 1
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,1

1,ALA,2
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 2
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,2

1,MET,3
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 3
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,3

1,GLY,4
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 4
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,4

1,SER,5
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 5
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,5

1,MET,6
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 6
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,6

1,SER,7
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 7
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,7

1,GLN,8
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 8
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,8

1,GLU,9
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 9
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,9

1,ARG,10
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 10
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,10

1,PRO,11
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 11
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,11

1,THR,12
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 12
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,12

1,PHE,13
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 13
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,13

1,TYR,14
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 14
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,14

1,ARG,15
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 15
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,15

1,GLN,16
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 16
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,16

1,GLU,17
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 17
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,17

1,LEU,18
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 18
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,18

1,ASN,19
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 19
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,19

1,LYS,20
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 20
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,20

1,THR,21
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 21
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,21

1,ILE,22
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 22
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,22

1,TRP,23
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 23
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,23

1,GLU,24
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 24
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,24

1,VAL,25
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 25
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,25

1,PRO,26
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 26
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,26

1,GLU,27
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 27
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,27

1,ARG,28
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 28
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,28

1,TYR,29
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 29
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,29

1,GLN,30
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 30
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,30

1,ASN,31
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 31
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,31

1,LEU,32
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 32
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,32

1,SER,33
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 33
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,33

1,PRO,34
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 34
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,34

1,VAL,35
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 35
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,35

1,GLY,36
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 36
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,36

1,SER,37
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 37
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,37

1,GLY,38
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 38
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,38

1,ALA,39
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 39
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,39

1,TYR,40
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 40
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,40

1,GLY,41
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 41
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,41

1,SER,42
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 42
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,42

1,VAL,43
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 43
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,43

1,CYS,44
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 44
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,44

1,ALA,45
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 45
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,45

1,ALA,46
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 46
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,46

1,PHE,47
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 47
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,47

1,ASP,48
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 48
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,48

1,THR,49
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 49
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,49

1,LYS,50
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 50
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,50

1,THR,51
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 51
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,51

1,GLY,52
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 52
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,52

1,LEU,53
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 53
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,53

1,ARG,54
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 54
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,54

1,VAL,55
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 55
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,55

1,ALA,56
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 56
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,56

1,VAL,57
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 57
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,57

1,LYS,58
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 58
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,58

1,LYS,59
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 59
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,59

1,LEU,60
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 60
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,60

1,SER,61
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 61
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,61

1,ARG,62
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 62
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,62

1,PRO,63
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 63
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,63

1,PHE,64
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 64
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,64

1,GLN,65
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 65
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,65

1,SER,66
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 66
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,66

1,ILE,67
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 67
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,67

1,ILE,68
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 68
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,68

1,HIS,69
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 69
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,69

1,ALA,70
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 70
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,70

1,LYS,71
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 71
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,71

1,ARG,72
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 72
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,72

1,THR,73
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 73
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,73

1,TYR,74
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 74
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,74

1,ARG,75
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 75
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,75

1,GLU,76
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 76
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,76

1,LEU,77
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 77
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,77

1,ARG,78
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 78
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,78

1,LEU,79
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 79
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,79

1,LEU,80
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 80
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,80

1,LYS,81
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 81
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,81

1,HIS,82
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 82
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,82

1,MET,83
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 83
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,83

1,LYS,84
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 84
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,84

1,HIS,85
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 85
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,85

1,GLU,86
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 86
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,86

1,ASN,87
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 87
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,87

1,VAL,88
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 88
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,88

1,ILE,89
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 89
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,89

1,GLY,90
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 90
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,90

1,LEU,91
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 91
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,91

1,LEU,92
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 92
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,92

1,ASP,93
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 93
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,93

1,VAL,94
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 94
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,94

1,PHE,95
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 95
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,95

1,THR,96
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 96
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,96

1,PRO,97
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 97
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,97

1,ALA,98
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 98
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,98

1,ARG,99
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 99
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,99

1,SER,100
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 100
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,100

1,LEU,101
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 101
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,101

1,GLU,102
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 102
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,102

1,GLU,103
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 103
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,103

1,PHE,104
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 104
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,104

1,ASN,105
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 105
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,105

1,ASP,106
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 106
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,106

1,VAL,107
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 107
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,107

1,TYR,108
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 108
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,108

1,LEU,109
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 109
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,109

1,VAL,110
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 110
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,110

1,THR,111
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 111
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,111

1,HIS,112
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 112
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,112

1,LEU,113
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 113
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,113

1,MET,114
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 114
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,114

1,GLY,115
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 115
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,115

1,ALA,116
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 116
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,116

1,ASP,117
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 117
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,117

1,LEU,118
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 118
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,118

1,ASN,119
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 119
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,119

1,ASN,120
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 120
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,120

1,ILE,121
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 121
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,121

1,VAL,122
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 122
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,122

1,LYS,123
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 123
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,123

1,SER,124
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 124
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,124

1,GLN,125
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 125
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,125

1,LYS,126
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 126
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,126

1,LEU,127
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 127
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,127

1,THR,128
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 128
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,128

1,ASP,129
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 129
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,129

1,ASP,130
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 130
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,130

1,HIS,131
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 131
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,131

1,VAL,132
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 132
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,132

1,GLN,133
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 133
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,133

1,PHE,134
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 134
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,134

1,LEU,135
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 135
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,135

1,ILE,136
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 136
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,136

1,TYR,137
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 137
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,137

1,GLN,138
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 138
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,138

1,ILE,139
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 139
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,139

1,LEU,140
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 140
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,140

1,ARG,141
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 141
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,141

1,GLY,142
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 142
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,142

1,LEU,143
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 143
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,143

1,LYS,144
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 144
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,144

1,TYR,145
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 145
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,145

1,ILE,146
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 146
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,146

1,HIS,147
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 147
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,147

1,SER,148
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 148
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,148

1,ALA,149
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 149
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,149

1,ASP,150
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 150
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,150

1,ILE,151
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 151
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,151

1,ILE,152
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 152
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,152

1,HIS,153
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 153
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,153

1,ARG,154
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 154
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,154

1,ASP,155
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 155
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,155

1,LEU,156
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 156
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,156

1,LYS,157
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 157
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,157

1,PRO,158
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 158
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,158

1,SER,159
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 159
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,159

1,ASN,160
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 160
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,160

1,LEU,161
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 161
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,161

1,ALA,162
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 162
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,162

1,VAL,163
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 163
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,163

1,ASN,164
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 164
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,164

1,GLU,165
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 165
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,165

1,ASP,166
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 166
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,166

1,SER,167
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 167
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,167

1,GLU,168
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 168
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,168

1,LEU,169
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 169
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,169

1,LYS,170
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 170
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,170

1,ILE,171
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 171
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,171

1,LEU,172
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 172
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,172

1,ASP,173
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 173
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,173

1,PHE,174
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 174
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,174

1,GLY,175
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 175
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,175

1,LEU,176
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 176
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,176

1,ALA,177
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 177
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,177

1,ARG,178
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 178
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,178

1,HIS,179
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 179
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,179

1,THR,180
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 180
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,180

1,ASP,181
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 181
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,181

1,ASP,182
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 182
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,182

1,GLU,183
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 183
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,183

1,MET,184
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 184
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,184

1,THR,185
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 185
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,185

1,GLY,186
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 186
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,186

1,TYR,187
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 187
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,187

1,VAL,188
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 188
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,188

1,ALA,189
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 189
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,189

1,THR,190
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 190
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,190

1,ARG,191
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 191
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,191

1,TRP,192
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 192
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,192

1,TYR,193
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 193
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,193

1,ARG,194
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 194
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,194

1,ALA,195
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 195
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,195

1,PRO,196
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 196
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,196

1,GLU,197
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 197
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,197

1,ILE,198
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 198
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,198

1,MET,199
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 199
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,199

1,LEU,200
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 200
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,200

1,ASN,201
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 201
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,201

1,TRP,202
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 202
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,202

1,MET,203
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 203
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,203

1,HIS,204
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 204
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,204

1,TYR,205
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 205
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,205

1,ASN,206
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 206
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,206

1,GLN,207
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 207
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,207

1,THR,208
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 208
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,208

1,VAL,209
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 209
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,209

1,ASP,210
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 210
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,210

1,ILE,211
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 211
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,211

1,TRP,212
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 212
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,212

1,SER,213
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 213
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,213

1,VAL,214
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 214
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,214

1,GLY,215
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 215
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,215

1,CYS,216
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 216
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,216

1,ILE,217
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 217
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,217

1,MET,218
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 218
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,218

1,ALA,219
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 219
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,219

1,GLU,220
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 220
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,220

1,LEU,221
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 221
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,221

1,LEU,222
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 222
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,222

1,THR,223
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 223
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,223

1,GLY,224
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 224
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,224

1,ARG,225
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 225
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,225

1,THR,226
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 226
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,226

1,LEU,227
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 227
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,227

1,PHE,228
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 228
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,228

1,PRO,229
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 229
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,229

1,GLY,230
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 230
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,230

1,THR,231
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 231
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,231

1,ASP,232
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 232
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,232

1,HIS,233
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 233
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,233

1,ILE,234
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 234
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,234

1,ASP,235
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 235
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,235

1,GLN,236
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 236
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,236

1,LEU,237
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 237
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,237

1,LYS,238
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 238
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,238

1,LEU,239
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 239
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,239

1,ILE,240
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 240
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,240

1,LEU,241
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 241
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,241

1,ARG,242
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 242
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,242

1,LEU,243
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 243
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,243

1,VAL,244
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 244
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,244

1,GLY,245
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 245
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,245

1,THR,246
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 246
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,246

1,PRO,247
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 247
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,247

1,GLY,248
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 248
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,248

1,ALA,249
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 249
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,249

1,GLU,250
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 250
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,250

1,LEU,251
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 251
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,251

1,LEU,252
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 252
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,252

1,LYS,253
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 253
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,253

1,LYS,254
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 254
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,254

1,ILE,255
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 255
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,255

1,SER,256
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 256
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,256

1,SER,257
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 257
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,257

1,GLU,258
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 258
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,258

1,SER,259
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 259
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,259

1,ALA,260
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 260
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,260

1,ARG,261
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 261
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,261

1,ASN,262
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 262
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,262

1,TYR,263
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 263
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,263

1,ILE,264
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 264
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,264

1,GLN,265
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 265
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,265

1,SER,266
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 266
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,266

1,LEU,267
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 267
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,267

1,THR,268
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 268
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,268

1,GLN,269
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 269
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,269

1,MET,270
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 270
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,270

1,PRO,271
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 271
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,271

1,LYS,272
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 272
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,272

1,MET,273
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 273
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,273

1,ASN,274
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 274
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,274

1,PHE,275
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 275
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,275

1,ALA,276
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 276
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,276

1,ASN,277
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 277
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,277

1,VAL,278
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 278
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,278

1,PHE,279
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 279
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,279

1,ILE,280
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 280
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,280

1,GLY,281
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 281
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,281

1,ALA,282
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 282
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,282

1,ASN,283
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 283
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,283

1,PRO,284
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 284
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,284

1,LEU,285
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 285
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,285

1,ALA,286
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 286
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,286

1,VAL,287
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 287
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,287

1,ASP,288
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 288
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,288

1,LEU,289
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 289
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,289

1,LEU,290
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 290
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,290

1,GLU,291
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 291
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,291

1,LYS,292
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 292
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,292

1,MET,293
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 293
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,293

1,LEU,294
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 294
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,294

1,VAL,295
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 295
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,295

1,LEU,296
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 296
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,296

1,ASP,297
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 297
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,297

1,SER,298
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 298
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,298

1,ASP,299
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 299
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,299

1,LYS,300
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 300
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,300

1,ARG,301
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 301
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,301

1,ILE,302
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 302
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,302

1,THR,303
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 303
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,303

1,ALA,304
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 304
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,304

1,ALA,305
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 305
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,305

1,GLN,306
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 306
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,306

1,ALA,307
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 307
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,307

1,LEU,308
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 308
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,308

1,ALA,309
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 309
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,309

1,HIS,310
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 310
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,310

1,ALA,311
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 311
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,311

1,TYR,312
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 312
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,312

1,PHE,313
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 313
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,313

1,ALA,314
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 314
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,314

1,GLN,315
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 315
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,315

1,TYR,316
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 316
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,316

1,HIS,317
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 317
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,317

1,ASP,318
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 318
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,318

1,PRO,319
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 319
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,319

1,ASP,320
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 320
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,320

1,ASP,321
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 321
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,321

1,GLU,322
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 322
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,322

1,PRO,323
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 323
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,323

1,VAL,324
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 324
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,324

1,ALA,325
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 325
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,325

1,ASP,326
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 326
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,326

1,PRO,327
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 327
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,327

1,TYR,328
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 328
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,328

1,ASP,329
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 329
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,329

1,GLN,330
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 330
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,330

1,SER,331
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 331
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,331

1,PHE,332
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 332
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,332

1,GLU,333
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 333
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,333

1,SER,334
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 334
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,334

1,ARG,335
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 335
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,335

1,ASP,336
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 336
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,336

1,LEU,337
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 337
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,337

1,LEU,338
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 338
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,338

1,ILE,339
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 339
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,339

1,ASP,340
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 340
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,340

1,GLU,341
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 341
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,341

1,TRP,342
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 342
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,342

1,LYS,343
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 343
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,343

1,SER,344
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 344
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,344

1,LEU,345
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 345
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,345

1,THR,346
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 346
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,346

1,TYR,347
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 347
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,347

1,ASP,348
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 348
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,348

1,GLU,349
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 349
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,349

1,VAL,350
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 350
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,350

1,ILE,351
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 351
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,351

1,SER,352
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 352
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,352

1,PHE,353
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 353
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,353

1,VAL,354
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 354
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,354

1,PRO,355
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 355
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,355

1,PRO,356
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 356
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,356

1,PRO,357
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 357
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,357

1,LEU,358
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 358
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,358

1,ASP,359
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 359
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,359

1,GLN,360
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 360
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,360

1,GLU,361
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 361
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,361

1,GLU,362
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 362
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,362

1,MET,363
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 363
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,363

1,GLU,364
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 364
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,364

1,SER,365
type: entity poly seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5WJJ/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 365
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,365

1,1
type: entity src gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/1
entity src gen.entity id: 1
entity src gen.pdbx src id: 1
entity src gen.gene src common name: Human
entity src gen.pdbx alt source flag: sample
entity src gen.pdbx beg seq num: 1
entity src gen.pdbx end seq num: 365
entity src gen.pdbx gene src gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
entity src gen.pdbx gene src ncbi taxonomy id: 9606
entity src gen.pdbx gene src scientific name: Homo sapiens
entity src gen.pdbx host org ncbi taxonomy id: 274590
entity src gen.pdbx host org scientific name: Baculovirus expression vector pFastBac1-HM
entity src gen.pdbx host org strain: Sf9
entity src gen.pdbx host org vector type: plasmid
entity src gen.pdbx seq type: Biological sequence
entity src gen.plasmid name: pFastBacHT
link to taxonomy source: taxonomy:9606
link to taxonomy host: taxonomy:274590

taxonomy:9606

taxonomy:274590

5WJJ,X-RAY DIFFRACTION
type: exptl
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
exptl.entry id: 5WJJ
exptl.method: X-RAY DIFFRACTION
exptl.crystals number: 1

http://rdf.wwpdb.org/pdb/5WJJ/exptl_crystal_grow/1
type: exptl crystal grow
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to exptl crystal: http://rdf.wwpdb.org/pdb/5WJJ/exptl_crystal/1
exptl crystal grow.crystal id: 1
exptl crystal grow.method: VAPOR DIFFUSION, SITTING DROP
exptl crystal grow.p h: 7.4
exptl crystal grow.pdbx details: 18.% PEG 3350, 0.06M MES, 0.04M MES_Na
exptl crystal grow.temp: 293

Structure model,1,2
type: pdbx audit revision category
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 1
pdbx audit revision category.revision ordinal: 2
pdbx audit revision category.category: citation

Structure model,2
referenced by pdbx audit revision category: Structure model,1,2
referenced by pdbx audit revision group: Structure model,1,2
type: pdbx audit revision history
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 2
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 1
pdbx audit revision history.revision date: 2018-02-14
referenced by pdbx audit revision item: Structure model,4,2
referenced by pdbx audit revision item: Structure model,1,2
referenced by pdbx audit revision item: Structure model,2,2
referenced by pdbx audit revision item: Structure model,3,2

Structure model,2,3
type: pdbx audit revision category
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 2
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: chem_comp_atom

Structure model,3
referenced by pdbx audit revision category: Structure model,2,3
referenced by pdbx audit revision category: Structure model,3,3
referenced by pdbx audit revision category: Structure model,4,3
referenced by pdbx audit revision group: Structure model,2,3
referenced by pdbx audit revision group: Structure model,3,3
type: pdbx audit revision history
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 3
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 2
pdbx audit revision history.revision date: 2024-03-13
referenced by pdbx audit revision item: Structure model,6,3
referenced by pdbx audit revision item: Structure model,5,3

Structure model,3,3
type: pdbx audit revision category
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 3
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: chem_comp_bond

Structure model,4,3
type: pdbx audit revision category
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 4
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: database_2

Structure model,1,1
type: pdbx audit revision details
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,1
pdbx audit revision details.data content type: Structure model
pdbx audit revision details.ordinal: 1
pdbx audit revision details.revision ordinal: 1
pdbx audit revision details.provider: repository
pdbx audit revision details.type: Initial release

Structure model,1
referenced by pdbx audit revision details: Structure model,1,1
type: pdbx audit revision history
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 1
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 0
pdbx audit revision history.revision date: 2018-01-17

Structure model,1,2
type: pdbx audit revision group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 1
pdbx audit revision group.revision ordinal: 2
pdbx audit revision group.group: Database references

Structure model,2,3
type: pdbx audit revision group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 2
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Data collection

Structure model,3,3
type: pdbx audit revision group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 3
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Database references

Structure model,1,2
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 1
pdbx audit revision item.revision ordinal: 2
pdbx audit revision item.item: _citation.journal_volume

Structure model,2,2
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 2
pdbx audit revision item.revision ordinal: 2
pdbx audit revision item.item: _citation.page_first

Structure model,3,2
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 3
pdbx audit revision item.revision ordinal: 2
pdbx audit revision item.item: _citation.page_last

Structure model,4,2
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,2
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 4
pdbx audit revision item.revision ordinal: 2
pdbx audit revision item.item: _citation.year

Structure model,5,3
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 5
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _database_2.pdbx_DOI

Structure model,6,3
type: pdbx audit revision item
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 6
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _database_2.pdbx_database_accession

5WJJ
type: pdbx database status
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
pdbx database status.entry id: 5WJJ
pdbx database status.sg entry: N
pdbx database status.deposit site: RCSB
pdbx database status.pdb format compatible: Y
pdbx database status.process site: RCSB
pdbx database status.recvd initial deposition date: 2017-07-23
pdbx database status.status code: REL
pdbx database status.status code sf: REL

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_distant_solvent_atoms/1
type: pdbx distant solvent atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: HOH
pdbx distant solvent atoms.id: 1
pdbx distant solvent atoms.pdb model num: 1
pdbx distant solvent atoms.auth asym id: A
pdbx distant solvent atoms.auth atom id: O
pdbx distant solvent atoms.auth comp id: HOH
pdbx distant solvent atoms.auth seq id: 980
pdbx distant solvent atoms.neighbor macromolecule distance: 6.01

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_entity_instance_feature/1
type: pdbx entity instance feature
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx entity instance feature.ordinal: 1
pdbx entity instance feature.auth comp id: AQY
pdbx entity instance feature.comp id: AQY
pdbx entity instance feature.feature type: SUBJECT OF INVESTIGATION

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_entity_nonpoly/2
type: pdbx entity nonpoly
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/2
pdbx entity nonpoly.entity id: 2
pdbx entity nonpoly.comp id: AQY
pdbx entity nonpoly.name: N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_entity_nonpoly/3
type: pdbx entity nonpoly
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/3
pdbx entity nonpoly.entity id: 3
pdbx entity nonpoly.comp id: HOH
pdbx entity nonpoly.name: water

B,1
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: B
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: LIG
pdbx nonpoly scheme.auth seq num: 501
pdbx nonpoly scheme.entity id: 2
pdbx nonpoly scheme.mon id: AQY
pdbx nonpoly scheme.pdb mon id: AQY
pdbx nonpoly scheme.pdb seq num: 501
pdbx nonpoly scheme.pdb strand id: A

C,1
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 200
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 601
pdbx nonpoly scheme.pdb strand id: A

C,2
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 346
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 602
pdbx nonpoly scheme.pdb strand id: A

C,3
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 129
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 603
pdbx nonpoly scheme.pdb strand id: A

C,4
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 72
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 604
pdbx nonpoly scheme.pdb strand id: A

C,5
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 158
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 605
pdbx nonpoly scheme.pdb strand id: A

C,6
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 197
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 606
pdbx nonpoly scheme.pdb strand id: A

C,7
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 35
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 607
pdbx nonpoly scheme.pdb strand id: A

C,8
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 177
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 608
pdbx nonpoly scheme.pdb strand id: A

C,9
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 304
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 609
pdbx nonpoly scheme.pdb strand id: A

C,10
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 294
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 610
pdbx nonpoly scheme.pdb strand id: A

C,11
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 370
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 611
pdbx nonpoly scheme.pdb strand id: A

C,12
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 60
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 612
pdbx nonpoly scheme.pdb strand id: A

C,13
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 174
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 613
pdbx nonpoly scheme.pdb strand id: A

C,14
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 213
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 614
pdbx nonpoly scheme.pdb strand id: A

C,15
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 331
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 615
pdbx nonpoly scheme.pdb strand id: A

C,16
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 188
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 616
pdbx nonpoly scheme.pdb strand id: A

C,17
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 64
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 617
pdbx nonpoly scheme.pdb strand id: A

C,18
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 80
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 618
pdbx nonpoly scheme.pdb strand id: A

C,19
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 162
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 619
pdbx nonpoly scheme.pdb strand id: A

C,20
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 15
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 620
pdbx nonpoly scheme.pdb strand id: A

C,21
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 189
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 621
pdbx nonpoly scheme.pdb strand id: A

C,22
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 312
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 622
pdbx nonpoly scheme.pdb strand id: A

C,23
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 13
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 623
pdbx nonpoly scheme.pdb strand id: A

C,24
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 168
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 624
pdbx nonpoly scheme.pdb strand id: A

C,25
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 50
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 625
pdbx nonpoly scheme.pdb strand id: A

C,26
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 133
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 626
pdbx nonpoly scheme.pdb strand id: A

C,27
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 137
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 627
pdbx nonpoly scheme.pdb strand id: A

C,28
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 130
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 628
pdbx nonpoly scheme.pdb strand id: A

C,29
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 181
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 629
pdbx nonpoly scheme.pdb strand id: A

C,30
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 22
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 630
pdbx nonpoly scheme.pdb strand id: A

C,31
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 21
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 631
pdbx nonpoly scheme.pdb strand id: A

C,32
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 198
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 632
pdbx nonpoly scheme.pdb strand id: A

C,33
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 29
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 633
pdbx nonpoly scheme.pdb strand id: A

C,34
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 61
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 634
pdbx nonpoly scheme.pdb strand id: A

C,35
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 211
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 635
pdbx nonpoly scheme.pdb strand id: A

C,36
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 151
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 636
pdbx nonpoly scheme.pdb strand id: A

C,37
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 143
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 637
pdbx nonpoly scheme.pdb strand id: A

C,38
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 136
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 638
pdbx nonpoly scheme.pdb strand id: A

C,39
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 279
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 639
pdbx nonpoly scheme.pdb strand id: A

C,40
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 141
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 640
pdbx nonpoly scheme.pdb strand id: A

C,41
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 120
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 641
pdbx nonpoly scheme.pdb strand id: A

C,42
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 361
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 642
pdbx nonpoly scheme.pdb strand id: A

C,43
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 39
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 643
pdbx nonpoly scheme.pdb strand id: A

C,44
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 54
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 644
pdbx nonpoly scheme.pdb strand id: A

C,45
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 69
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 645
pdbx nonpoly scheme.pdb strand id: A

C,46
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 3
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 646
pdbx nonpoly scheme.pdb strand id: A

C,47
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 159
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 647
pdbx nonpoly scheme.pdb strand id: A

C,48
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 126
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 648
pdbx nonpoly scheme.pdb strand id: A

C,49
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 202
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 649
pdbx nonpoly scheme.pdb strand id: A

C,50
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 14
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 650
pdbx nonpoly scheme.pdb strand id: A

C,51
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 17
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 651
pdbx nonpoly scheme.pdb strand id: A

C,52
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 44
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 652
pdbx nonpoly scheme.pdb strand id: A

C,53
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 183
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 653
pdbx nonpoly scheme.pdb strand id: A

C,54
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 23
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 654
pdbx nonpoly scheme.pdb strand id: A

C,55
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 38
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 655
pdbx nonpoly scheme.pdb strand id: A

C,56
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 187
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 656
pdbx nonpoly scheme.pdb strand id: A

C,57
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 101
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 657
pdbx nonpoly scheme.pdb strand id: A

C,58
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 62
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 658
pdbx nonpoly scheme.pdb strand id: A

C,59
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 191
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 659
pdbx nonpoly scheme.pdb strand id: A

C,60
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 9
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 660
pdbx nonpoly scheme.pdb strand id: A

C,61
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 31
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 661
pdbx nonpoly scheme.pdb strand id: A

C,62
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 205
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 662
pdbx nonpoly scheme.pdb strand id: A

C,63
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 90
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 663
pdbx nonpoly scheme.pdb strand id: A

C,64
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 78
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 664
pdbx nonpoly scheme.pdb strand id: A

C,65
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 282
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 665
pdbx nonpoly scheme.pdb strand id: A

C,66
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 376
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 666
pdbx nonpoly scheme.pdb strand id: A

C,67
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 298
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 667
pdbx nonpoly scheme.pdb strand id: A

C,68
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 332
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 668
pdbx nonpoly scheme.pdb strand id: A

C,69
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 214
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 669
pdbx nonpoly scheme.pdb strand id: A

C,70
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 85
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 670
pdbx nonpoly scheme.pdb strand id: A

C,71
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 216
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 671
pdbx nonpoly scheme.pdb strand id: A

C,72
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 43
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 672
pdbx nonpoly scheme.pdb strand id: A

C,73
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 261
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 673
pdbx nonpoly scheme.pdb strand id: A

C,74
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 55
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 674
pdbx nonpoly scheme.pdb strand id: A

C,75
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 176
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 675
pdbx nonpoly scheme.pdb strand id: A

C,76
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 8
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 676
pdbx nonpoly scheme.pdb strand id: A

C,77
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 193
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 677
pdbx nonpoly scheme.pdb strand id: A

C,78
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 132
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 678
pdbx nonpoly scheme.pdb strand id: A

C,79
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 295
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 679
pdbx nonpoly scheme.pdb strand id: A

C,80
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 212
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 680
pdbx nonpoly scheme.pdb strand id: A

C,81
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 123
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 681
pdbx nonpoly scheme.pdb strand id: A

C,82
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 109
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 682
pdbx nonpoly scheme.pdb strand id: A

C,83
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 180
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 683
pdbx nonpoly scheme.pdb strand id: A

C,84
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 190
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 684
pdbx nonpoly scheme.pdb strand id: A

C,85
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 247
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 685
pdbx nonpoly scheme.pdb strand id: A

C,86
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 274
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 686
pdbx nonpoly scheme.pdb strand id: A

C,87
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 203
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 687
pdbx nonpoly scheme.pdb strand id: A

C,88
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 94
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 688
pdbx nonpoly scheme.pdb strand id: A

C,89
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 347
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 689
pdbx nonpoly scheme.pdb strand id: A

C,90
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 33
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 690
pdbx nonpoly scheme.pdb strand id: A

C,91
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 313
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 691
pdbx nonpoly scheme.pdb strand id: A

C,92
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 372
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 692
pdbx nonpoly scheme.pdb strand id: A

C,93
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 160
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 693
pdbx nonpoly scheme.pdb strand id: A

C,94
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 11
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 694
pdbx nonpoly scheme.pdb strand id: A

C,95
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 206
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 695
pdbx nonpoly scheme.pdb strand id: A

C,96
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 19
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 696
pdbx nonpoly scheme.pdb strand id: A

C,97
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 269
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 697
pdbx nonpoly scheme.pdb strand id: A

C,98
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 24
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 698
pdbx nonpoly scheme.pdb strand id: A

C,99
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 63
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 699
pdbx nonpoly scheme.pdb strand id: A

C,100
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 115
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 700
pdbx nonpoly scheme.pdb strand id: A

C,101
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 95
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 701
pdbx nonpoly scheme.pdb strand id: A

C,102
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 88
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 702
pdbx nonpoly scheme.pdb strand id: A

C,103
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 59
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 703
pdbx nonpoly scheme.pdb strand id: A

C,104
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 234
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 704
pdbx nonpoly scheme.pdb strand id: A

C,105
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 217
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 705
pdbx nonpoly scheme.pdb strand id: A

C,106
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 199
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 706
pdbx nonpoly scheme.pdb strand id: A

C,107
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 108
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 707
pdbx nonpoly scheme.pdb strand id: A

C,108
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 84
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 708
pdbx nonpoly scheme.pdb strand id: A

C,109
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 27
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 709
pdbx nonpoly scheme.pdb strand id: A

C,110
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 377
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 710
pdbx nonpoly scheme.pdb strand id: A

C,111
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 175
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 711
pdbx nonpoly scheme.pdb strand id: A

C,112
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 314
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 712
pdbx nonpoly scheme.pdb strand id: A

C,113
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 169
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 713
pdbx nonpoly scheme.pdb strand id: A

C,114
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 148
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 714
pdbx nonpoly scheme.pdb strand id: A

C,115
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 91
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 715
pdbx nonpoly scheme.pdb strand id: A

C,116
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 223
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 716
pdbx nonpoly scheme.pdb strand id: A

C,117
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 119
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 717
pdbx nonpoly scheme.pdb strand id: A

C,118
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 311
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 718
pdbx nonpoly scheme.pdb strand id: A

C,119
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 45
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 719
pdbx nonpoly scheme.pdb strand id: A

C,120
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 86
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 720
pdbx nonpoly scheme.pdb strand id: A

C,121
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 28
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 721
pdbx nonpoly scheme.pdb strand id: A

C,122
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 243
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 722
pdbx nonpoly scheme.pdb strand id: A

C,123
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 58
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 723
pdbx nonpoly scheme.pdb strand id: A

C,124
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 124
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 371
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 724
pdbx nonpoly scheme.pdb strand id: A

C,125
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 125
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 104
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 725
pdbx nonpoly scheme.pdb strand id: A

C,126
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 126
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 68
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 726
pdbx nonpoly scheme.pdb strand id: A

C,127
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 127
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 149
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 727
pdbx nonpoly scheme.pdb strand id: A

C,128
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 128
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 140
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 728
pdbx nonpoly scheme.pdb strand id: A

C,129
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 129
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 192
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 729
pdbx nonpoly scheme.pdb strand id: A

C,130
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 130
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 57
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 730
pdbx nonpoly scheme.pdb strand id: A

C,131
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 131
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 106
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 731
pdbx nonpoly scheme.pdb strand id: A

C,132
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 132
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 232
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 732
pdbx nonpoly scheme.pdb strand id: A

C,133
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 133
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 52
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 733
pdbx nonpoly scheme.pdb strand id: A

C,134
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 134
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 284
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 734
pdbx nonpoly scheme.pdb strand id: A

C,135
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 135
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 237
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 735
pdbx nonpoly scheme.pdb strand id: A

C,136
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 136
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 71
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 736
pdbx nonpoly scheme.pdb strand id: A

C,137
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 137
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 96
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 737
pdbx nonpoly scheme.pdb strand id: A

C,138
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 138
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 105
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 738
pdbx nonpoly scheme.pdb strand id: A

C,139
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 139
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 248
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 739
pdbx nonpoly scheme.pdb strand id: A

C,140
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 140
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 163
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 740
pdbx nonpoly scheme.pdb strand id: A

C,141
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 141
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 18
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 741
pdbx nonpoly scheme.pdb strand id: A

C,142
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 142
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 742
pdbx nonpoly scheme.pdb strand id: A

C,143
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 143
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 156
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 743
pdbx nonpoly scheme.pdb strand id: A

C,144
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 144
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 266
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 744
pdbx nonpoly scheme.pdb strand id: A

C,145
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 145
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 42
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 745
pdbx nonpoly scheme.pdb strand id: A

C,146
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 146
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 6
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 746
pdbx nonpoly scheme.pdb strand id: A

C,147
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 147
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 48
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 747
pdbx nonpoly scheme.pdb strand id: A

C,148
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 148
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 66
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 748
pdbx nonpoly scheme.pdb strand id: A

C,149
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 149
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 235
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 749
pdbx nonpoly scheme.pdb strand id: A

C,150
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 150
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 178
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 750
pdbx nonpoly scheme.pdb strand id: A

C,151
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 151
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 231
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 751
pdbx nonpoly scheme.pdb strand id: A

C,152
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 152
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 752
pdbx nonpoly scheme.pdb strand id: A

C,153
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 153
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 258
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 753
pdbx nonpoly scheme.pdb strand id: A

C,154
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 154
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 300
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 754
pdbx nonpoly scheme.pdb strand id: A

C,155
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 155
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 135
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 755
pdbx nonpoly scheme.pdb strand id: A

C,156
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 156
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 301
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 756
pdbx nonpoly scheme.pdb strand id: A

C,157
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 157
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 165
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 757
pdbx nonpoly scheme.pdb strand id: A

C,158
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 158
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 117
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 758
pdbx nonpoly scheme.pdb strand id: A

C,159
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 159
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 30
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 759
pdbx nonpoly scheme.pdb strand id: A

C,160
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 160
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 5
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 760
pdbx nonpoly scheme.pdb strand id: A

C,161
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 161
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 7
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 761
pdbx nonpoly scheme.pdb strand id: A

C,162
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 162
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 110
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 762
pdbx nonpoly scheme.pdb strand id: A

C,163
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 163
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 75
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 763
pdbx nonpoly scheme.pdb strand id: A

C,164
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 164
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 20
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 764
pdbx nonpoly scheme.pdb strand id: A

C,165
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 165
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 79
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 765
pdbx nonpoly scheme.pdb strand id: A

C,166
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 166
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 87
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 766
pdbx nonpoly scheme.pdb strand id: A

C,167
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 167
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 196
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 767
pdbx nonpoly scheme.pdb strand id: A

C,168
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 168
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 4
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 768
pdbx nonpoly scheme.pdb strand id: A

C,169
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 169
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 134
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 769
pdbx nonpoly scheme.pdb strand id: A

C,170
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 170
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 25
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 770
pdbx nonpoly scheme.pdb strand id: A

C,171
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 171
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 26
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 771
pdbx nonpoly scheme.pdb strand id: A

C,172
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 172
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 348
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 772
pdbx nonpoly scheme.pdb strand id: A

C,173
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 173
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 47
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 773
pdbx nonpoly scheme.pdb strand id: A

C,174
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 174
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 56
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 774
pdbx nonpoly scheme.pdb strand id: A

C,175
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 175
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 326
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 775
pdbx nonpoly scheme.pdb strand id: A

C,176
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 176
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 195
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 776
pdbx nonpoly scheme.pdb strand id: A

C,177
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 177
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 46
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 777
pdbx nonpoly scheme.pdb strand id: A

C,178
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 178
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 53
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 778
pdbx nonpoly scheme.pdb strand id: A

C,179
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 179
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 345
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 779
pdbx nonpoly scheme.pdb strand id: A

C,180
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 180
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 350
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 780
pdbx nonpoly scheme.pdb strand id: A

C,181
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 181
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 93
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 781
pdbx nonpoly scheme.pdb strand id: A

C,182
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 182
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 118
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 782
pdbx nonpoly scheme.pdb strand id: A

C,183
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 183
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 306
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 783
pdbx nonpoly scheme.pdb strand id: A

C,184
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 184
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 89
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 784
pdbx nonpoly scheme.pdb strand id: A

C,185
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 185
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 70
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 785
pdbx nonpoly scheme.pdb strand id: A

C,186
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 186
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 363
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 786
pdbx nonpoly scheme.pdb strand id: A

C,187
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 187
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 32
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 787
pdbx nonpoly scheme.pdb strand id: A

C,188
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 188
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 256
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 788
pdbx nonpoly scheme.pdb strand id: A

C,189
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 189
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 267
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 789
pdbx nonpoly scheme.pdb strand id: A

C,190
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 190
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 97
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 790
pdbx nonpoly scheme.pdb strand id: A

C,191
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 191
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 10
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 791
pdbx nonpoly scheme.pdb strand id: A

C,192
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 192
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 73
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 792
pdbx nonpoly scheme.pdb strand id: A

C,193
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 193
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 49
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 793
pdbx nonpoly scheme.pdb strand id: A

C,194
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 194
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 330
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 794
pdbx nonpoly scheme.pdb strand id: A

C,195
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 195
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 228
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 795
pdbx nonpoly scheme.pdb strand id: A

C,196
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 196
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 240
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 796
pdbx nonpoly scheme.pdb strand id: A

C,197
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 197
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 204
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 797
pdbx nonpoly scheme.pdb strand id: A

C,198
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 198
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 37
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 798
pdbx nonpoly scheme.pdb strand id: A

C,199
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 199
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 82
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 799
pdbx nonpoly scheme.pdb strand id: A

C,200
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 200
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 334
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 800
pdbx nonpoly scheme.pdb strand id: A

C,201
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 201
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 113
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 801
pdbx nonpoly scheme.pdb strand id: A

C,202
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 202
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 254
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 802
pdbx nonpoly scheme.pdb strand id: A

C,203
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 203
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 319
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 803
pdbx nonpoly scheme.pdb strand id: A

C,204
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 204
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 201
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 804
pdbx nonpoly scheme.pdb strand id: A

C,205
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 205
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 241
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 805
pdbx nonpoly scheme.pdb strand id: A

C,206
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 206
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 368
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 806
pdbx nonpoly scheme.pdb strand id: A

C,207
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 207
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 255
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 807
pdbx nonpoly scheme.pdb strand id: A

C,208
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 208
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 219
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 808
pdbx nonpoly scheme.pdb strand id: A

C,209
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 209
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 246
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 809
pdbx nonpoly scheme.pdb strand id: A

C,210
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 210
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 112
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 810
pdbx nonpoly scheme.pdb strand id: A

C,211
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 211
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 324
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 811
pdbx nonpoly scheme.pdb strand id: A

C,212
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 212
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 147
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 812
pdbx nonpoly scheme.pdb strand id: A

C,213
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 213
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 325
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 813
pdbx nonpoly scheme.pdb strand id: A

C,214
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 214
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 260
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 814
pdbx nonpoly scheme.pdb strand id: A

C,215
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 215
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 225
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 815
pdbx nonpoly scheme.pdb strand id: A

C,216
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 216
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 335
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 816
pdbx nonpoly scheme.pdb strand id: A

C,217
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 217
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 222
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 817
pdbx nonpoly scheme.pdb strand id: A

C,218
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 218
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 379
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 818
pdbx nonpoly scheme.pdb strand id: A

C,219
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 219
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 238
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 819
pdbx nonpoly scheme.pdb strand id: A

C,220
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 220
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 321
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 820
pdbx nonpoly scheme.pdb strand id: A

C,221
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 221
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 278
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 821
pdbx nonpoly scheme.pdb strand id: A

C,222
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 222
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 226
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 822
pdbx nonpoly scheme.pdb strand id: A

C,223
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 223
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 218
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 823
pdbx nonpoly scheme.pdb strand id: A

C,224
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 224
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 264
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 824
pdbx nonpoly scheme.pdb strand id: A

C,225
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 225
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 51
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 825
pdbx nonpoly scheme.pdb strand id: A

C,226
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 226
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 288
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 826
pdbx nonpoly scheme.pdb strand id: A

C,227
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 227
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 114
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 827
pdbx nonpoly scheme.pdb strand id: A

C,228
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 228
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 116
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 828
pdbx nonpoly scheme.pdb strand id: A

C,229
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 229
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 34
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 829
pdbx nonpoly scheme.pdb strand id: A

C,230
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 230
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 12
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 830
pdbx nonpoly scheme.pdb strand id: A

C,231
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 231
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 289
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 831
pdbx nonpoly scheme.pdb strand id: A

C,232
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 232
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 121
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 832
pdbx nonpoly scheme.pdb strand id: A

C,233
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 233
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 245
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 833
pdbx nonpoly scheme.pdb strand id: A

C,234
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 234
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 122
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 834
pdbx nonpoly scheme.pdb strand id: A

C,235
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 235
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 296
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 835
pdbx nonpoly scheme.pdb strand id: A

C,236
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 236
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 40
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 836
pdbx nonpoly scheme.pdb strand id: A

C,237
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 237
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 74
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 837
pdbx nonpoly scheme.pdb strand id: A

C,238
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 238
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 233
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 838
pdbx nonpoly scheme.pdb strand id: A

C,239
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 239
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 221
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 839
pdbx nonpoly scheme.pdb strand id: A

C,240
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 240
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 224
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 840
pdbx nonpoly scheme.pdb strand id: A

C,241
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 241
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 146
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 841
pdbx nonpoly scheme.pdb strand id: A

C,242
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 242
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 366
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 842
pdbx nonpoly scheme.pdb strand id: A

C,243
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 243
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 263
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 843
pdbx nonpoly scheme.pdb strand id: A

C,244
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 244
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 65
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 844
pdbx nonpoly scheme.pdb strand id: A

C,245
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 245
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 358
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 845
pdbx nonpoly scheme.pdb strand id: A

C,246
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 246
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 170
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 846
pdbx nonpoly scheme.pdb strand id: A

C,247
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 247
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 265
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 847
pdbx nonpoly scheme.pdb strand id: A

C,248
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 248
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 131
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 848
pdbx nonpoly scheme.pdb strand id: A

C,249
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 249
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 286
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 849
pdbx nonpoly scheme.pdb strand id: A

C,250
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 250
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 239
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 850
pdbx nonpoly scheme.pdb strand id: A

C,251
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 251
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 277
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 851
pdbx nonpoly scheme.pdb strand id: A

C,252
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 252
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 67
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 852
pdbx nonpoly scheme.pdb strand id: A

C,253
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 253
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 315
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 853
pdbx nonpoly scheme.pdb strand id: A

C,254
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 254
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 329
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 854
pdbx nonpoly scheme.pdb strand id: A

C,255
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 255
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 338
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 855
pdbx nonpoly scheme.pdb strand id: A

C,256
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 256
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 364
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 856
pdbx nonpoly scheme.pdb strand id: A

C,257
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 257
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 128
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 857
pdbx nonpoly scheme.pdb strand id: A

C,258
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 258
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 76
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 858
pdbx nonpoly scheme.pdb strand id: A

C,259
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 259
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 369
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 859
pdbx nonpoly scheme.pdb strand id: A

C,260
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 260
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 41
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 860
pdbx nonpoly scheme.pdb strand id: A

C,261
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 261
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 182
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 861
pdbx nonpoly scheme.pdb strand id: A

C,262
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 262
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 270
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 862
pdbx nonpoly scheme.pdb strand id: A

C,263
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 263
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 280
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 863
pdbx nonpoly scheme.pdb strand id: A

C,264
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 264
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 36
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 864
pdbx nonpoly scheme.pdb strand id: A

C,265
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 265
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 308
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 865
pdbx nonpoly scheme.pdb strand id: A

C,266
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 266
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 139
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 866
pdbx nonpoly scheme.pdb strand id: A

C,267
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 267
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 152
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 867
pdbx nonpoly scheme.pdb strand id: A

C,268
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 268
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 124
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 868
pdbx nonpoly scheme.pdb strand id: A

C,269
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 269
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 144
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 869
pdbx nonpoly scheme.pdb strand id: A

C,270
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 270
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 236
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 870
pdbx nonpoly scheme.pdb strand id: A

C,271
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 271
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 323
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 871
pdbx nonpoly scheme.pdb strand id: A

C,272
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 272
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 164
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 872
pdbx nonpoly scheme.pdb strand id: A

C,273
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 273
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 150
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 873
pdbx nonpoly scheme.pdb strand id: A

C,274
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 274
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 92
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 874
pdbx nonpoly scheme.pdb strand id: A

C,275
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 275
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 184
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 875
pdbx nonpoly scheme.pdb strand id: A

C,276
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 276
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 173
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 876
pdbx nonpoly scheme.pdb strand id: A

C,277
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 277
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 292
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 877
pdbx nonpoly scheme.pdb strand id: A

C,278
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 278
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 161
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 878
pdbx nonpoly scheme.pdb strand id: A

C,279
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 279
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 290
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 879
pdbx nonpoly scheme.pdb strand id: A

C,280
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 280
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 343
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 880
pdbx nonpoly scheme.pdb strand id: A

C,281
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 281
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 374
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 881
pdbx nonpoly scheme.pdb strand id: A

C,282
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 282
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 157
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 882
pdbx nonpoly scheme.pdb strand id: A

C,283
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 283
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 293
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 883
pdbx nonpoly scheme.pdb strand id: A

C,284
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 284
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 272
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 884
pdbx nonpoly scheme.pdb strand id: A

C,285
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 285
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 342
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 885
pdbx nonpoly scheme.pdb strand id: A

C,286
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 286
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 102
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 886
pdbx nonpoly scheme.pdb strand id: A

C,287
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 287
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 229
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 887
pdbx nonpoly scheme.pdb strand id: A

C,288
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 288
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 283
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 888
pdbx nonpoly scheme.pdb strand id: A

C,289
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 289
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 380
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 889
pdbx nonpoly scheme.pdb strand id: A

C,290
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 290
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 210
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 890
pdbx nonpoly scheme.pdb strand id: A

C,291
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 291
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 367
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 891
pdbx nonpoly scheme.pdb strand id: A

C,292
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 292
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 155
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 892
pdbx nonpoly scheme.pdb strand id: A

C,293
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 293
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 271
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 893
pdbx nonpoly scheme.pdb strand id: A

C,294
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 294
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 310
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 894
pdbx nonpoly scheme.pdb strand id: A

C,295
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 295
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 285
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 895
pdbx nonpoly scheme.pdb strand id: A

C,296
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 296
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 252
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 896
pdbx nonpoly scheme.pdb strand id: A

C,297
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 297
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 253
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 897
pdbx nonpoly scheme.pdb strand id: A

C,298
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 298
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 249
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 898
pdbx nonpoly scheme.pdb strand id: A

C,299
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 299
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 244
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 899
pdbx nonpoly scheme.pdb strand id: A

C,300
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 300
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 194
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 900
pdbx nonpoly scheme.pdb strand id: A

C,301
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 301
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 16
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 901
pdbx nonpoly scheme.pdb strand id: A

C,302
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 302
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 186
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 902
pdbx nonpoly scheme.pdb strand id: A

C,303
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 303
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 340
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 903
pdbx nonpoly scheme.pdb strand id: A

C,304
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 304
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 281
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 904
pdbx nonpoly scheme.pdb strand id: A

C,305
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 305
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 287
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 905
pdbx nonpoly scheme.pdb strand id: A

C,306
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 306
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 355
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 906
pdbx nonpoly scheme.pdb strand id: A

C,307
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 307
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 111
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 907
pdbx nonpoly scheme.pdb strand id: A

C,308
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 308
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 359
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 908
pdbx nonpoly scheme.pdb strand id: A

C,309
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 309
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 273
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 909
pdbx nonpoly scheme.pdb strand id: A

C,310
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 310
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 107
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 910
pdbx nonpoly scheme.pdb strand id: A

C,311
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 311
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 328
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 911
pdbx nonpoly scheme.pdb strand id: A

C,312
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 312
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 227
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 912
pdbx nonpoly scheme.pdb strand id: A

C,313
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 313
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 302
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 913
pdbx nonpoly scheme.pdb strand id: A

C,314
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 314
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 185
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 914
pdbx nonpoly scheme.pdb strand id: A

C,315
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 315
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 103
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 915
pdbx nonpoly scheme.pdb strand id: A

C,316
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 316
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 375
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 916
pdbx nonpoly scheme.pdb strand id: A

C,317
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 317
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 250
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 917
pdbx nonpoly scheme.pdb strand id: A

C,318
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 318
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 268
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 918
pdbx nonpoly scheme.pdb strand id: A

C,319
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 319
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 275
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 919
pdbx nonpoly scheme.pdb strand id: A

C,320
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 320
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 153
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 920
pdbx nonpoly scheme.pdb strand id: A

C,321
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 321
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 337
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 921
pdbx nonpoly scheme.pdb strand id: A

C,322
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 322
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 142
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 922
pdbx nonpoly scheme.pdb strand id: A

C,323
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 323
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 333
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 923
pdbx nonpoly scheme.pdb strand id: A

C,324
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 324
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 179
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 924
pdbx nonpoly scheme.pdb strand id: A

C,325
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 325
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 207
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 925
pdbx nonpoly scheme.pdb strand id: A

C,326
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 326
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 322
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 926
pdbx nonpoly scheme.pdb strand id: A

C,327
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 327
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 299
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 927
pdbx nonpoly scheme.pdb strand id: A

C,328
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 328
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 320
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 928
pdbx nonpoly scheme.pdb strand id: A

C,329
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 329
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 209
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 929
pdbx nonpoly scheme.pdb strand id: A

C,330
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 330
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 259
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 930
pdbx nonpoly scheme.pdb strand id: A

C,331
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 331
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 83
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 931
pdbx nonpoly scheme.pdb strand id: A

C,332
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 332
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 362
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 932
pdbx nonpoly scheme.pdb strand id: A

C,333
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 333
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 242
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 933
pdbx nonpoly scheme.pdb strand id: A

C,334
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 334
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 230
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 934
pdbx nonpoly scheme.pdb strand id: A

C,335
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 335
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 208
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 935
pdbx nonpoly scheme.pdb strand id: A

C,336
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 336
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 98
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 936
pdbx nonpoly scheme.pdb strand id: A

C,337
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 337
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 341
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 937
pdbx nonpoly scheme.pdb strand id: A

C,338
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 338
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 336
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 938
pdbx nonpoly scheme.pdb strand id: A

C,339
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 339
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 291
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 939
pdbx nonpoly scheme.pdb strand id: A

C,340
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 340
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 378
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 940
pdbx nonpoly scheme.pdb strand id: A

C,341
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 341
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 352
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 941
pdbx nonpoly scheme.pdb strand id: A

C,342
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 342
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 357
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 942
pdbx nonpoly scheme.pdb strand id: A

C,343
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 343
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 145
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 943
pdbx nonpoly scheme.pdb strand id: A

C,344
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 344
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 81
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 944
pdbx nonpoly scheme.pdb strand id: A

C,345
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 345
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 127
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 945
pdbx nonpoly scheme.pdb strand id: A

C,346
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 346
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 353
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 946
pdbx nonpoly scheme.pdb strand id: A

C,347
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 347
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 354
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 947
pdbx nonpoly scheme.pdb strand id: A

C,348
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 348
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 257
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 948
pdbx nonpoly scheme.pdb strand id: A

C,349
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 349
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 77
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 949
pdbx nonpoly scheme.pdb strand id: A

C,350
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 350
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 339
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 950
pdbx nonpoly scheme.pdb strand id: A

C,351
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 351
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 309
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 951
pdbx nonpoly scheme.pdb strand id: A

C,352
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 352
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 154
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 952
pdbx nonpoly scheme.pdb strand id: A

C,353
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 353
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 365
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 953
pdbx nonpoly scheme.pdb strand id: A

C,354
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 354
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 215
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 954
pdbx nonpoly scheme.pdb strand id: A

C,355
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 355
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 356
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 955
pdbx nonpoly scheme.pdb strand id: A

C,356
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 356
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 220
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 956
pdbx nonpoly scheme.pdb strand id: A

C,357
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 357
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 317
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 957
pdbx nonpoly scheme.pdb strand id: A

C,358
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 358
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 316
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 958
pdbx nonpoly scheme.pdb strand id: A

C,359
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 359
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 344
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 959
pdbx nonpoly scheme.pdb strand id: A

C,360
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 360
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 166
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 960
pdbx nonpoly scheme.pdb strand id: A

C,361
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 361
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 138
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 961
pdbx nonpoly scheme.pdb strand id: A

C,362
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 362
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 360
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 962
pdbx nonpoly scheme.pdb strand id: A

C,363
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 363
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 172
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 963
pdbx nonpoly scheme.pdb strand id: A

C,364
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 364
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 100
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 964
pdbx nonpoly scheme.pdb strand id: A

C,365
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 365
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 303
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 965
pdbx nonpoly scheme.pdb strand id: A

C,366
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 366
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 276
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 966
pdbx nonpoly scheme.pdb strand id: A

C,367
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 367
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 167
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 967
pdbx nonpoly scheme.pdb strand id: A

C,368
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 368
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 318
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 968
pdbx nonpoly scheme.pdb strand id: A

C,369
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 369
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 125
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 969
pdbx nonpoly scheme.pdb strand id: A

C,370
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 370
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 251
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 970
pdbx nonpoly scheme.pdb strand id: A

C,371
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 371
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 99
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 971
pdbx nonpoly scheme.pdb strand id: A

C,372
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 372
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 373
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 972
pdbx nonpoly scheme.pdb strand id: A

C,373
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 373
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 171
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 973
pdbx nonpoly scheme.pdb strand id: A

C,374
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 374
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 307
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 974
pdbx nonpoly scheme.pdb strand id: A

C,375
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 375
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 305
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 975
pdbx nonpoly scheme.pdb strand id: A

C,376
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 376
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 349
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 976
pdbx nonpoly scheme.pdb strand id: A

C,377
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 377
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 297
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 977
pdbx nonpoly scheme.pdb strand id: A

C,378
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 378
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 327
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 978
pdbx nonpoly scheme.pdb strand id: A

C,379
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 379
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 351
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 979
pdbx nonpoly scheme.pdb strand id: A

C,380
type: pdbx nonpoly scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 380
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 262
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 980
pdbx nonpoly scheme.pdb strand id: A

A,1,GLY,1
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,1
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: -4
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
referenced by pdbx poly seq scheme: A,1,GLY,1
referenced by pdbx poly seq scheme: A,1,ALA,2
referenced by pdbx poly seq scheme: A,1,MET,3
referenced by pdbx poly seq scheme: A,1,GLY,4
referenced by pdbx poly seq scheme: A,1,SER,5
referenced by pdbx poly seq scheme: A,1,MET,6
referenced by pdbx poly seq scheme: A,1,SER,7
referenced by pdbx poly seq scheme: A,1,GLN,8
referenced by pdbx poly seq scheme: A,1,GLU,9
referenced by pdbx poly seq scheme: A,1,ARG,10
referenced by pdbx poly seq scheme: A,1,PRO,11
referenced by pdbx poly seq scheme: A,1,THR,12
referenced by pdbx poly seq scheme: A,1,PHE,13
referenced by pdbx poly seq scheme: A,1,TYR,14
referenced by pdbx poly seq scheme: A,1,ARG,15
referenced by pdbx poly seq scheme: A,1,GLN,16
referenced by pdbx poly seq scheme: A,1,GLU,17
referenced by pdbx poly seq scheme: A,1,LEU,18
referenced by pdbx poly seq scheme: A,1,ASN,19
referenced by pdbx poly seq scheme: A,1,LYS,20
referenced by pdbx poly seq scheme: A,1,THR,21
referenced by pdbx poly seq scheme: A,1,ILE,22
referenced by pdbx poly seq scheme: A,1,TRP,23
referenced by pdbx poly seq scheme: A,1,GLU,24
referenced by pdbx poly seq scheme: A,1,VAL,25
referenced by pdbx poly seq scheme: A,1,PRO,26
referenced by pdbx poly seq scheme: A,1,GLU,27
referenced by pdbx poly seq scheme: A,1,ARG,28
referenced by pdbx poly seq scheme: A,1,TYR,29
referenced by pdbx poly seq scheme: A,1,GLN,30
referenced by pdbx poly seq scheme: A,1,ASN,31
referenced by pdbx poly seq scheme: A,1,LEU,32
referenced by pdbx poly seq scheme: A,1,SER,33
referenced by pdbx poly seq scheme: A,1,PRO,34
referenced by pdbx poly seq scheme: A,1,VAL,35
referenced by pdbx poly seq scheme: A,1,GLY,36
referenced by pdbx poly seq scheme: A,1,SER,37
referenced by pdbx poly seq scheme: A,1,GLY,38
referenced by pdbx poly seq scheme: A,1,ALA,39
referenced by pdbx poly seq scheme: A,1,TYR,40
referenced by pdbx poly seq scheme: A,1,GLY,41
referenced by pdbx poly seq scheme: A,1,SER,42
referenced by pdbx poly seq scheme: A,1,VAL,43
referenced by pdbx poly seq scheme: A,1,CYS,44
referenced by pdbx poly seq scheme: A,1,ALA,45
referenced by pdbx poly seq scheme: A,1,ALA,46
referenced by pdbx poly seq scheme: A,1,PHE,47
referenced by pdbx poly seq scheme: A,1,ASP,48
referenced by pdbx poly seq scheme: A,1,THR,49
referenced by pdbx poly seq scheme: A,1,LYS,50
referenced by pdbx poly seq scheme: A,1,THR,51
referenced by pdbx poly seq scheme: A,1,GLY,52
referenced by pdbx poly seq scheme: A,1,LEU,53
referenced by pdbx poly seq scheme: A,1,ARG,54
referenced by pdbx poly seq scheme: A,1,VAL,55
referenced by pdbx poly seq scheme: A,1,ALA,56
referenced by pdbx poly seq scheme: A,1,VAL,57
referenced by pdbx poly seq scheme: A,1,LYS,58
referenced by pdbx poly seq scheme: A,1,LYS,59
referenced by pdbx poly seq scheme: A,1,LEU,60
referenced by pdbx poly seq scheme: A,1,SER,61
referenced by pdbx poly seq scheme: A,1,ARG,62
referenced by pdbx poly seq scheme: A,1,PRO,63
referenced by pdbx poly seq scheme: A,1,PHE,64
referenced by pdbx poly seq scheme: A,1,GLN,65
referenced by pdbx poly seq scheme: A,1,SER,66
referenced by pdbx poly seq scheme: A,1,ILE,67
referenced by pdbx poly seq scheme: A,1,ILE,68
referenced by pdbx poly seq scheme: A,1,HIS,69
referenced by pdbx poly seq scheme: A,1,ALA,70
referenced by pdbx poly seq scheme: A,1,LYS,71
referenced by pdbx poly seq scheme: A,1,ARG,72
referenced by pdbx poly seq scheme: A,1,THR,73
referenced by pdbx poly seq scheme: A,1,TYR,74
referenced by pdbx poly seq scheme: A,1,ARG,75
referenced by pdbx poly seq scheme: A,1,GLU,76
referenced by pdbx poly seq scheme: A,1,LEU,77
referenced by pdbx poly seq scheme: A,1,ARG,78
referenced by pdbx poly seq scheme: A,1,LEU,79
referenced by pdbx poly seq scheme: A,1,LEU,80

A,1,ALA,2
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,2
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb seq num: -3
pdbx poly seq scheme.pdb strand id: A

A,1,MET,3
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,3
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb seq num: -2
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,4
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,4
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb seq num: -1
pdbx poly seq scheme.pdb strand id: A

A,1,SER,5
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,5
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb seq num: 0
pdbx poly seq scheme.pdb strand id: A

A,1,MET,6
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,6
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb seq num: 1
pdbx poly seq scheme.pdb strand id: A

A,1,SER,7
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,7
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb seq num: 2
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,8
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,8
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb seq num: 3
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,9
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,9
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb seq num: 4
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,10
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,10
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 5
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 5
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,11
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,11
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 6
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 6
pdbx poly seq scheme.pdb strand id: A

A,1,THR,12
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,12
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 7
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 7
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,13
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,13
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 8
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 8
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,14
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,14
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 9
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 9
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,15
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,15
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 10
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 10
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,16
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,16
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 11
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 11
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,17
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,17
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 12
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 12
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,18
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,18
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 13
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 13
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,19
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,19
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 14
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 14
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,20
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,20
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 15
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 15
pdbx poly seq scheme.pdb strand id: A

A,1,THR,21
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,21
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 16
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 16
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,22
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,22
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 17
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 17
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,23
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TRP,23
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 18
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 18
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,24
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,24
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 19
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 19
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,25
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,25
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 20
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 20
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,26
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,26
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 21
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 21
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,27
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,27
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 22
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 22
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,28
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,28
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 23
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 23
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,29
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,29
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 24
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 24
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,30
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,30
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 25
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 25
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,31
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,31
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 26
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 26
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,32
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,32
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 27
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 27
pdbx poly seq scheme.pdb strand id: A

A,1,SER,33
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,33
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 28
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 28
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,34
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,34
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 29
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 29
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,35
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,35
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 30
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 30
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,36
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,36
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 31
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 31
pdbx poly seq scheme.pdb strand id: A

A,1,SER,37
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,37
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 32
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 32
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,38
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,38
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 33
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 33
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,39
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,39
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 34
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 34
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,40
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,40
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 35
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 35
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,41
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,41
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 36
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 36
pdbx poly seq scheme.pdb strand id: A

A,1,SER,42
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,42
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 37
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 37
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,43
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,43
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 38
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 38
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,44
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,CYS,44
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 39
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 39
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,45
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,45
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 40
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 40
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,46
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,46
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 41
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 41
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,47
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,47
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 42
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 42
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,48
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,48
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 43
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 43
pdbx poly seq scheme.pdb strand id: A

A,1,THR,49
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,49
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 44
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 44
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,50
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,50
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 45
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 45
pdbx poly seq scheme.pdb strand id: A

A,1,THR,51
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,51
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 46
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 46
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,52
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,52
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 47
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 47
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,53
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,53
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 48
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 48
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,54
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,54
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 49
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 49
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,55
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,55
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 50
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 50
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,56
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,56
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 51
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 51
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,57
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,57
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 52
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 52
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,58
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,58
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 53
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 53
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,59
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,59
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 54
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 54
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,60
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,60
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 55
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 55
pdbx poly seq scheme.pdb strand id: A

A,1,SER,61
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,61
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 56
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 56
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,62
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,62
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 57
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 57
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,63
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,63
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 58
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 58
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,64
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,64
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 59
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 59
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,65
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,65
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 60
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 60
pdbx poly seq scheme.pdb strand id: A

A,1,SER,66
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,66
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 61
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 61
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,67
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,67
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 62
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 62
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,68
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,68
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 63
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 63
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,69
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,69
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 64
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 64
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,70
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,70
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 65
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 65
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,71
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,71
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 66
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 66
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,72
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,72
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 67
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 67
pdbx poly seq scheme.pdb strand id: A

A,1,THR,73
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,73
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 68
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 68
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,74
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,74
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 69
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 69
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,75
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,75
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 70
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 70
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,76
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,76
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 71
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 71
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,77
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,77
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 72
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 72
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,78
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,78
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 73
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 73
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,79
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,79
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 74
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 74
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,80
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,80
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 75
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 75
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,81
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,81
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 76
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 76
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,82
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,82
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 77
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 77
pdbx poly seq scheme.pdb strand id: A

A,1,MET,83
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,83
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 78
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 78
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,84
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,84
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 79
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 79
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,85
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,85
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 80
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 80
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,86
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,86
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 81
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 81
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,87
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,87
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 82
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 82
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,88
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,88
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 83
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 83
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,89
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,89
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 84
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 84
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,90
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,90
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 85
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 85
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,91
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,91
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 86
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 86
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,92
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,92
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 87
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 87
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,93
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,93
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 88
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 88
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,94
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,94
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 89
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 89
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,95
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,95
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 90
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 90
pdbx poly seq scheme.pdb strand id: A

A,1,THR,96
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,96
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 91
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 91
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,97
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,97
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 92
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 92
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,98
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,98
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 93
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 93
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,99
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,99
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 94
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 94
pdbx poly seq scheme.pdb strand id: A

A,1,SER,100
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,100
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 95
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 95
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,101
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,101
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 96
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 96
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,102
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,102
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 97
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 97
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,103
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,103
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 98
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 98
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,104
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,104
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 99
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 99
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,105
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,105
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 100
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 100
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,106
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,106
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 101
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 101
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,107
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,107
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 102
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 102
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,108
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,108
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 103
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 103
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,109
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,109
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 104
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 104
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,110
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,110
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 105
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 105
pdbx poly seq scheme.pdb strand id: A

A,1,THR,111
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,111
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 106
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 106
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,112
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,112
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 107
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 107
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,113
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,113
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 108
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 108
pdbx poly seq scheme.pdb strand id: A

A,1,MET,114
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,114
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 109
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,115
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,115
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 110
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,116
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,116
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 111
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 111
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,117
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,117
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 112
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 112
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,118
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,118
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 113
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 113
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,119
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,119
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 114
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 114
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,120
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,120
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 115
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 115
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,121
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,121
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 116
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 116
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,122
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,122
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 117
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 117
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,123
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,123
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 118
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 118
pdbx poly seq scheme.pdb strand id: A

A,1,SER,124
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,124
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 119
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 119
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,125
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,125
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 120
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 120
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,126
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,126
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 121
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 121
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,127
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,127
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 122
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 122
pdbx poly seq scheme.pdb strand id: A

A,1,THR,128
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,128
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 123
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 123
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,129
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,129
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 124
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 124
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,130
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,130
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 125
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 125
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,131
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,131
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 126
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 126
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,132
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,132
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 127
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 127
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,133
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,133
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 128
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 128
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,134
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,134
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 129
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 129
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,135
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,135
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 130
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 130
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,136
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,136
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 131
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 131
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,137
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,137
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 132
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 132
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,138
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,138
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 133
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 133
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,139
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,139
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 134
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 134
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,140
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,140
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 135
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 135
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,141
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,141
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 136
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 136
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,142
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,142
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 137
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 137
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,143
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,143
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 138
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 138
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,144
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,144
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 139
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 139
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,145
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,145
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 140
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 140
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,146
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,146
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 141
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 141
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,147
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,147
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 142
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 142
pdbx poly seq scheme.pdb strand id: A

A,1,SER,148
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,148
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 143
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 143
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,149
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,149
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 144
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 144
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,150
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,150
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 145
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 145
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,151
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,151
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 146
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 146
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,152
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,152
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 147
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 147
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,153
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,153
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 148
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 148
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,154
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,154
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 149
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 149
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,155
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,155
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 150
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 150
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,156
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,156
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 151
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 151
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,157
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,157
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 152
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 152
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,158
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,158
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 153
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 153
pdbx poly seq scheme.pdb strand id: A

A,1,SER,159
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,159
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 154
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 154
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,160
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,160
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 155
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 155
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,161
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,161
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 156
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 156
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,162
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,162
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 157
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 157
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,163
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,163
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 158
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 158
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,164
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,164
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 159
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 159
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,165
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,165
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 160
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 160
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,166
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,166
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 161
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 161
pdbx poly seq scheme.pdb strand id: A

A,1,SER,167
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,167
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 162
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 162
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,168
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,168
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 163
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 163
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,169
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,169
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 164
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 164
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,170
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,170
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 165
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 165
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,171
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,171
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 166
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 166
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,172
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,172
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 167
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 167
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,173
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,173
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 168
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 168
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,174
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,174
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 169
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 169
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,175
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,175
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 170
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 170
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,176
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,176
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 171
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 171
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,177
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,177
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 172
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 172
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,178
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,178
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 173
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 173
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,179
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,179
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 174
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 174
pdbx poly seq scheme.pdb strand id: A

A,1,THR,180
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,180
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 175
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 175
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,181
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,181
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 176
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 176
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,182
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,182
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 177
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 177
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,183
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,183
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb seq num: 178
pdbx poly seq scheme.pdb strand id: A

A,1,MET,184
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,184
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb seq num: 179
pdbx poly seq scheme.pdb strand id: A

A,1,THR,185
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,185
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb seq num: 180
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,186
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,186
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb seq num: 181
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,187
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,187
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb seq num: 182
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,188
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,188
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb seq num: 183
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,189
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,189
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 184
pdbx poly seq scheme.pdb strand id: A

A,1,THR,190
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,190
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 185
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,191
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,191
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 186
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,192
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TRP,192
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 187
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,193
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,193
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 188
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,194
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,194
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 189
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 189
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,195
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,195
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 190
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 190
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,196
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,196
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 191
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 191
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,197
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,197
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 192
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 192
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,198
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,198
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 193
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 193
pdbx poly seq scheme.pdb strand id: A

A,1,MET,199
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,199
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 194
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 194
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,200
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,200
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 195
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 195
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,201
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,201
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 196
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 196
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,202
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TRP,202
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 197
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 197
pdbx poly seq scheme.pdb strand id: A

A,1,MET,203
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,203
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb seq num: 198
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,204
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,204
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 199
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 199
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,205
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,205
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 200
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 200
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,206
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,206
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 201
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 201
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,207
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,207
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 202
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 202
pdbx poly seq scheme.pdb strand id: A

A,1,THR,208
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,208
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 203
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,209
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,209
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 204
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 204
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,210
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,210
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 205
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 205
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,211
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,211
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 206
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 206
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,212
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TRP,212
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 207
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 207
pdbx poly seq scheme.pdb strand id: A

A,1,SER,213
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,213
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 208
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 208
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,214
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,214
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 209
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 209
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,215
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,215
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 210
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 210
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,216
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,CYS,216
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 211
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 211
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,217
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,217
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 212
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 212
pdbx poly seq scheme.pdb strand id: A

A,1,MET,218
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,218
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 213
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 213
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,219
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,219
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 214
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 214
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,220
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,220
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 215
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 215
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,221
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,221
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 216
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 216
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,222
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,222
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 217
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 217
pdbx poly seq scheme.pdb strand id: A

A,1,THR,223
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,223
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 218
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 218
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,224
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,224
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 219
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 219
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,225
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,225
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 220
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 220
pdbx poly seq scheme.pdb strand id: A

A,1,THR,226
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,226
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 221
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 221
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,227
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,227
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 222
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 222
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,228
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,228
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 223
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 223
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,229
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,229
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 224
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 224
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,230
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,230
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 225
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 225
pdbx poly seq scheme.pdb strand id: A

A,1,THR,231
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,231
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 226
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 226
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,232
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,232
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 227
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 227
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,233
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,233
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 228
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 228
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,234
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,234
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 229
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 229
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,235
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,235
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 230
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 230
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,236
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,236
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 231
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 231
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,237
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,237
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 232
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 232
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,238
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,238
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 233
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 233
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,239
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,239
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 234
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 234
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,240
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,240
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 235
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 235
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,241
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,241
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 236
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 236
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,242
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,242
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 237
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 237
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,243
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,243
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 238
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 238
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,244
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,244
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 239
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 239
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,245
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,245
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 240
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 240
pdbx poly seq scheme.pdb strand id: A

A,1,THR,246
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,246
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 241
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 241
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,247
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,247
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 242
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 242
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,248
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,248
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 243
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 243
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,249
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,249
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 244
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 244
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,250
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,250
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 245
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 245
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,251
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,251
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 246
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 246
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,252
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,252
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 247
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 247
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,253
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,253
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 248
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 248
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,254
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,254
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 249
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 249
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,255
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,255
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 250
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 250
pdbx poly seq scheme.pdb strand id: A

A,1,SER,256
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,256
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 251
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 251
pdbx poly seq scheme.pdb strand id: A

A,1,SER,257
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,257
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 252
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 252
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,258
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,258
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 253
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 253
pdbx poly seq scheme.pdb strand id: A

A,1,SER,259
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,259
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 254
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 254
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,260
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,260
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 255
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 255
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,261
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,261
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 256
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 256
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,262
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,262
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 257
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 257
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,263
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,263
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 258
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 258
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,264
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,264
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 259
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 259
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,265
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,265
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 260
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 260
pdbx poly seq scheme.pdb strand id: A

A,1,SER,266
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,266
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb seq num: 261
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,267
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,267
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb seq num: 262
pdbx poly seq scheme.pdb strand id: A

A,1,THR,268
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,268
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb seq num: 263
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,269
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,269
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 264
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 264
pdbx poly seq scheme.pdb strand id: A

A,1,MET,270
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,270
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 265
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 265
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,271
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,271
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 266
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,272
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,272
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 267
pdbx poly seq scheme.pdb strand id: A

A,1,MET,273
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,273
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 268
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,274
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,274
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 269
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 269
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,275
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,275
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 270
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 270
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,276
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,276
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 271
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 271
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,277
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,277
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 272
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 272
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,278
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,278
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 273
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 273
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,279
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,279
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 274
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 274
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,280
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,280
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 275
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 275
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,281
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLY,281
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 276
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 276
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,282
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,282
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 277
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 277
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,283
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASN,283
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 278
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 278
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,284
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,284
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 279
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 279
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,285
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,285
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 280
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 280
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,286
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,286
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 281
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 281
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,287
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,287
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 282
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 282
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,288
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,288
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 283
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 283
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,289
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,289
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 284
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 284
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,290
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,290
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 285
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 285
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,291
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,291
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 286
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 286
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,292
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,292
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 287
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 287
pdbx poly seq scheme.pdb strand id: A

A,1,MET,293
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,293
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 288
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 288
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,294
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,294
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 289
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 289
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,295
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,295
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 290
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 290
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,296
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,296
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 291
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 291
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,297
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,297
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 292
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 292
pdbx poly seq scheme.pdb strand id: A

A,1,SER,298
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,298
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 293
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 293
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,299
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,299
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 294
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 294
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,300
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,300
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 295
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 295
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,301
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,301
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 296
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 296
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,302
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,302
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 297
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 297
pdbx poly seq scheme.pdb strand id: A

A,1,THR,303
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,303
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 303
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 298
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 303
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 298
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,304
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,304
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 304
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 299
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 304
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 299
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,305
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,305
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 305
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 300
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 305
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 300
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,306
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,306
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 306
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 301
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 306
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 301
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,307
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,307
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 307
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 302
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 307
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 302
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,308
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,308
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 308
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 303
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 308
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 303
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,309
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,309
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 309
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 304
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 309
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 304
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,310
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,310
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 310
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 305
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 310
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 305
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,311
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,311
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 311
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 306
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 311
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 306
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,312
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,312
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 312
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 307
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 312
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 307
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,313
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,313
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 313
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 308
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 313
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 308
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,314
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,314
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 314
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 309
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 314
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 309
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,315
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,315
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 315
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 310
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 315
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 310
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,316
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,316
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 316
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 311
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 316
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 311
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,317
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,HIS,317
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 317
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 312
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 317
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 312
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,318
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,318
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 318
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 313
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 318
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 313
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,319
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,319
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 319
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 314
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 319
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 314
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,320
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,320
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 320
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 315
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 320
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 315
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,321
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,321
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 321
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 316
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 321
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 316
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,322
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,322
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 322
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 317
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 322
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 317
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,323
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,323
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 323
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 318
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 323
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 318
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,324
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,324
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 324
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 319
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 324
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 319
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,325
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ALA,325
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 325
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 320
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 325
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 320
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,326
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,326
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 326
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 321
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 326
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 321
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,327
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,327
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 327
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 322
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 327
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 322
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,328
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,328
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 328
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 323
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 328
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 323
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,329
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,329
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 329
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 324
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 329
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 324
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,330
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,330
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 330
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 330
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 325
pdbx poly seq scheme.pdb strand id: A

A,1,SER,331
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,331
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 331
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 331
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 326
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,332
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,332
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 332
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 332
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 327
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,333
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,333
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 333
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 333
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 328
pdbx poly seq scheme.pdb strand id: A

A,1,SER,334
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,334
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 334
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 334
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 329
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,335
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ARG,335
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 335
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 330
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 335
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 330
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,336
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,336
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 336
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 331
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 336
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 331
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,337
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,337
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 337
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 332
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 337
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 332
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,338
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,338
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 338
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 333
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 338
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 333
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,339
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,339
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 339
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 334
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 339
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 334
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,340
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,340
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 340
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 335
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 340
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 335
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,341
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,341
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 341
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 336
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 341
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 336
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,342
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TRP,342
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 342
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 337
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 342
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 337
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,343
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LYS,343
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 343
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 338
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 343
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 338
pdbx poly seq scheme.pdb strand id: A

A,1,SER,344
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,344
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 344
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 339
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 344
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 339
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,345
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,345
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 345
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 340
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 345
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 340
pdbx poly seq scheme.pdb strand id: A

A,1,THR,346
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,THR,346
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 346
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 341
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 346
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 341
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,347
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,TYR,347
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 347
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 342
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 347
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 342
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,348
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,348
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 348
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 343
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 348
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 343
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,349
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,349
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 349
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 344
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 349
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 344
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,350
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,350
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 350
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 345
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 350
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 345
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,351
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ILE,351
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 351
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 346
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 351
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 346
pdbx poly seq scheme.pdb strand id: A

A,1,SER,352
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,352
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 352
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 347
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 352
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 347
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,353
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PHE,353
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 353
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 348
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 353
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 348
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,354
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,VAL,354
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 354
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 349
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 354
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 349
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,355
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,355
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 355
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 350
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 355
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 350
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,356
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,356
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 356
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 351
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 356
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 351
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,357
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,PRO,357
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 357
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 352
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 357
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 352
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,358
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,LEU,358
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 358
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 358
pdbx poly seq scheme.pdb seq num: 353
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,359
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,ASP,359
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 359
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 359
pdbx poly seq scheme.pdb seq num: 354
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,360
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLN,360
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 360
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 360
pdbx poly seq scheme.pdb seq num: 355
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,361
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,361
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 361
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 361
pdbx poly seq scheme.pdb seq num: 356
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,362
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,362
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 362
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 362
pdbx poly seq scheme.pdb seq num: 357
pdbx poly seq scheme.pdb strand id: A

A,1,MET,363
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,MET,363
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 363
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 363
pdbx poly seq scheme.pdb seq num: 358
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,364
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,GLU,364
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 364
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 364
pdbx poly seq scheme.pdb seq num: 359
pdbx poly seq scheme.pdb strand id: A

A,1,SER,365
type: pdbx poly seq scheme
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity poly seq: 1,SER,365
reference to struct asym: http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 365
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 365
pdbx poly seq scheme.pdb seq num: 360
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/1
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 1
pdbx refine tls.l11: 3.8794
pdbx refine tls.l12: -0.7483
pdbx refine tls.l13: 1.4728
pdbx refine tls.l22: 4.5449
pdbx refine tls.l23: -1.5067
pdbx refine tls.l33: 6.3073
pdbx refine tls.s11: 0.0624
pdbx refine tls.s12: 0.0003
pdbx refine tls.s13: -0.3235
pdbx refine tls.s21: -0.1899
pdbx refine tls.s22: 0.0569
pdbx refine tls.s23: 0.104
pdbx refine tls.s31: 0.5446
pdbx refine tls.s32: -0.2762
pdbx refine tls.s33: -0.1193
pdbx refine tls.t11: 0.1037
pdbx refine tls.t12: -0.0445
pdbx refine tls.t13: -0.0004
pdbx refine tls.t22: 0.0637
pdbx refine tls.t23: 0.0306
pdbx refine tls.t33: 0.0525
pdbx refine tls.method: refined
pdbx refine tls.origin x: 17.085
pdbx refine tls.origin y: -17.589
pdbx refine tls.origin z: 5.58
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/1

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/2
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 2
pdbx refine tls.l11: 1.7246
pdbx refine tls.l12: 0.3594
pdbx refine tls.l13: -0.9295
pdbx refine tls.l22: 0.963
pdbx refine tls.l23: 0.3592
pdbx refine tls.l33: 2.5779
pdbx refine tls.s11: -0.0263
pdbx refine tls.s12: 0.1367
pdbx refine tls.s13: -0.043
pdbx refine tls.s21: 0.0062
pdbx refine tls.s22: 0.0175
pdbx refine tls.s23: 0.0108
pdbx refine tls.s31: 0.1482
pdbx refine tls.s32: -0.0425
pdbx refine tls.s33: 0.0087
pdbx refine tls.t11: 0.0422
pdbx refine tls.t12: 0.0087
pdbx refine tls.t13: -0.0074
pdbx refine tls.t22: 0.0277
pdbx refine tls.t23: 0.005
pdbx refine tls.t33: 0.0117
pdbx refine tls.method: refined
pdbx refine tls.origin x: 25.068
pdbx refine tls.origin y: -9.176
pdbx refine tls.origin z: -1.944
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/2

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/3
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 3
pdbx refine tls.l11: 2.5967
pdbx refine tls.l12: -0.5209
pdbx refine tls.l13: -0.499
pdbx refine tls.l22: 2.8415
pdbx refine tls.l23: 0.49
pdbx refine tls.l33: 1.8916
pdbx refine tls.s11: -0.0126
pdbx refine tls.s12: 0.0594
pdbx refine tls.s13: -0.1729
pdbx refine tls.s21: -0.0047
pdbx refine tls.s22: -0.0204
pdbx refine tls.s23: 0.2006
pdbx refine tls.s31: 0.1248
pdbx refine tls.s32: -0.1831
pdbx refine tls.s33: 0.033
pdbx refine tls.t11: 0.0272
pdbx refine tls.t12: -0.0055
pdbx refine tls.t13: 0.0021
pdbx refine tls.t22: 0.0206
pdbx refine tls.t23: -0.0008
pdbx refine tls.t33: 0.0225
pdbx refine tls.method: refined
pdbx refine tls.origin x: 19.755
pdbx refine tls.origin y: 9.263
pdbx refine tls.origin z: 6.367
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/3

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/4
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 4
pdbx refine tls.l11: 10.1591
pdbx refine tls.l12: -2.6594
pdbx refine tls.l13: -0.6666
pdbx refine tls.l22: 1.0583
pdbx refine tls.l23: -1.3625
pdbx refine tls.l33: 6.8298
pdbx refine tls.s11: 0.0646
pdbx refine tls.s12: 1.4476
pdbx refine tls.s13: -0.5894
pdbx refine tls.s21: -0.1796
pdbx refine tls.s22: -0.32
pdbx refine tls.s23: 0.0818
pdbx refine tls.s31: 0.5521
pdbx refine tls.s32: -0.2254
pdbx refine tls.s33: 0.2554
pdbx refine tls.t11: 0.1557
pdbx refine tls.t12: -0.0766
pdbx refine tls.t13: 0.0713
pdbx refine tls.t22: 0.2599
pdbx refine tls.t23: -0.1296
pdbx refine tls.t33: 0.0894
pdbx refine tls.method: refined
pdbx refine tls.origin x: 19.504
pdbx refine tls.origin y: 16.438
pdbx refine tls.origin z: -9.856
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/4

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/5
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 5
pdbx refine tls.l11: 1.4566
pdbx refine tls.l12: -0.1905
pdbx refine tls.l13: 0.4565
pdbx refine tls.l22: 1.216
pdbx refine tls.l23: 0.1355
pdbx refine tls.l33: 2.4313
pdbx refine tls.s11: -0.0185
pdbx refine tls.s12: 0.1255
pdbx refine tls.s13: 0.1356
pdbx refine tls.s21: -0.1347
pdbx refine tls.s22: 0.063
pdbx refine tls.s23: 0.0024
pdbx refine tls.s31: -0.1479
pdbx refine tls.s32: -0.1455
pdbx refine tls.s33: -0.0445
pdbx refine tls.t11: 0.0446
pdbx refine tls.t12: -0.0013
pdbx refine tls.t13: 0.0076
pdbx refine tls.t22: 0.0335
pdbx refine tls.t23: 0.0206
pdbx refine tls.t33: 0.0187
pdbx refine tls.method: refined
pdbx refine tls.origin x: 16.004
pdbx refine tls.origin y: 23.31
pdbx refine tls.origin z: -7.424
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/5

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/6
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 6
pdbx refine tls.l11: 1.3932
pdbx refine tls.l12: -0.2584
pdbx refine tls.l13: -1.959
pdbx refine tls.l22: 0.5327
pdbx refine tls.l23: 1.4579
pdbx refine tls.l33: 6.5037
pdbx refine tls.s11: 0.0824
pdbx refine tls.s12: 0.3689
pdbx refine tls.s13: 0.1828
pdbx refine tls.s21: -0.2348
pdbx refine tls.s22: -0.0134
pdbx refine tls.s23: 0.084
pdbx refine tls.s31: -0.9966
pdbx refine tls.s32: -0.5094
pdbx refine tls.s33: -0.069
pdbx refine tls.t11: 0.237
pdbx refine tls.t12: 0.0281
pdbx refine tls.t13: -0.0212
pdbx refine tls.t22: 0.1406
pdbx refine tls.t23: 0.0184
pdbx refine tls.t33: 0.1568
pdbx refine tls.method: refined
pdbx refine tls.origin x: 15.891
pdbx refine tls.origin y: 30.825
pdbx refine tls.origin z: -4.673
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/6

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/7
type: pdbx refine tls
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx refine tls.id: 7
pdbx refine tls.l11: 0.471
pdbx refine tls.l12: -0.2976
pdbx refine tls.l13: -0.1206
pdbx refine tls.l22: 1.7837
pdbx refine tls.l23: 0.918
pdbx refine tls.l33: 0.64
pdbx refine tls.s11: -0.0223
pdbx refine tls.s12: -0.0039
pdbx refine tls.s13: 0.0054
pdbx refine tls.s21: -0.0096
pdbx refine tls.s22: 0.0827
pdbx refine tls.s23: -0.1129
pdbx refine tls.s31: 0.0318
pdbx refine tls.s32: 0.081
pdbx refine tls.s33: -0.0605
pdbx refine tls.t11: 0.0498
pdbx refine tls.t12: -0.0031
pdbx refine tls.t13: 0.0172
pdbx refine tls.t22: 0.0514
pdbx refine tls.t23: 0.0029
pdbx refine tls.t33: 0.0198
pdbx refine tls.method: refined
pdbx refine tls.origin x: 30.794
pdbx refine tls.origin y: 7.294
pdbx refine tls.origin z: 0.484
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/7

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/1
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/1
pdbx refine tls group.id: 1
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 5
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 49
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 1

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/2
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/2
pdbx refine tls group.id: 2
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 50
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 115
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 2

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/3
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/3
pdbx refine tls group.id: 3
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 119
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 173
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 3

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/4
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/4
pdbx refine tls group.id: 4
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 184
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 203
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 4

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/5
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/5
pdbx refine tls group.id: 5
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 204
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 254
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 5

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/6
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/6
pdbx refine tls group.id: 6
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 255
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 280
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 6

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls_group/7
type: pdbx refine tls group
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_refine_tls/7
pdbx refine tls group.id: 7
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 281
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 352
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 7

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_struct_assembly/1
type: pdbx struct assembly
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx struct assembly.id: 1
pdbx struct assembly.details: author_and_software_defined_assembly
pdbx struct assembly.method details: PISA
pdbx struct assembly.oligomeric count: 1
pdbx struct assembly.oligomeric details: monomeric
referenced by pdbx struct assembly gen: 1,A,B,C,1
referenced by pdbx struct assembly auth evidence: 1,1

1,1
type: pdbx struct assembly auth evidence
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_struct_assembly/1
pdbx struct assembly auth evidence.assembly id: 1
pdbx struct assembly auth evidence.id: 1
pdbx struct assembly auth evidence.experimental support: none

1,A,B,C,1
type: pdbx struct assembly gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/5WJJ/pdbx_struct_assembly/1
pdbx struct assembly gen.assembly id: 1
pdbx struct assembly gen.asym id list: A,B,C
pdbx struct assembly gen.oper expression: 1

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_struct_oper_list/1
type: pdbx struct oper list
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx struct oper list.id: 1
pdbx struct oper list.matrix11: 1
pdbx struct oper list.matrix12: 0
pdbx struct oper list.matrix13: 0
pdbx struct oper list.matrix21: 0
pdbx struct oper list.matrix22: 1
pdbx struct oper list.matrix23: 0
pdbx struct oper list.matrix31: 0
pdbx struct oper list.matrix32: 0
pdbx struct oper list.matrix33: 1
pdbx struct oper list.name: 1_555
pdbx struct oper list.symmetry operation: x,y,z
pdbx struct oper list.type: identity operation
pdbx struct oper list.vector1: 0
pdbx struct oper list.vector2: 0
pdbx struct oper list.vector3: 0

1,2,AA1
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: GLN
pdbx struct sheet hbond.range 1 auth seq id: 11
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: GLN
pdbx struct sheet hbond.range 1 label seq id: 16
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: TRP
pdbx struct sheet hbond.range 2 auth seq id: 18
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: TRP
pdbx struct sheet hbond.range 2 label seq id: 23

AA1
referenced by pdbx struct sheet hbond: 1,2,AA1
type: struct sheet
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
struct sheet.id: AA1
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AA1
referenced by struct sheet range: 2,AA1
referenced by struct sheet range: 1,AA1

1,2,AA2
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA2
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: GLY
pdbx struct sheet hbond.range 1 auth seq id: 31
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: GLY
pdbx struct sheet hbond.range 1 label seq id: 36
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: VAL
pdbx struct sheet hbond.range 2 auth seq id: 38
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: VAL
pdbx struct sheet hbond.range 2 label seq id: 43

AA2
referenced by pdbx struct sheet hbond: 1,2,AA2
referenced by pdbx struct sheet hbond: 2,3,AA2
referenced by pdbx struct sheet hbond: 3,4,AA2
referenced by pdbx struct sheet hbond: 4,5,AA2
type: struct sheet
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
struct sheet.id: AA2
struct sheet.number strands: 5
referenced by struct sheet order: 4,5,AA2
referenced by struct sheet range: 5,AA2
referenced by struct sheet order: 1,2,AA2
referenced by struct sheet order: 2,3,AA2
referenced by struct sheet order: 3,4,AA2
referenced by struct sheet range: 1,AA2
referenced by struct sheet range: 2,AA2
referenced by struct sheet range: 3,AA2
referenced by struct sheet range: 4,AA2

2,3,AA2
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: AA2
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ASP
pdbx struct sheet hbond.range 1 auth seq id: 43
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ASP
pdbx struct sheet hbond.range 1 label seq id: 48
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 48
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 53

3,4,AA2
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
pdbx struct sheet hbond.range id 1: 3
pdbx struct sheet hbond.range id 2: 4
pdbx struct sheet hbond.sheet id: AA2
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LYS
pdbx struct sheet hbond.range 1 auth seq id: 53
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LYS
pdbx struct sheet hbond.range 1 label seq id: 58
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 104
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 109

4,5,AA2
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
pdbx struct sheet hbond.range id 1: 4
pdbx struct sheet hbond.range id 2: 5
pdbx struct sheet hbond.sheet id: AA2
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: VAL
pdbx struct sheet hbond.range 1 auth seq id: 105
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: VAL
pdbx struct sheet hbond.range 1 label seq id: 110
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: ASP
pdbx struct sheet hbond.range 2 auth seq id: 88
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: ASP
pdbx struct sheet hbond.range 2 label seq id: 93

1,2,AA3
type: pdbx struct sheet hbond
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA3
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA3
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ALA
pdbx struct sheet hbond.range 1 auth seq id: 157
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ALA
pdbx struct sheet hbond.range 1 label seq id: 162
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LYS
pdbx struct sheet hbond.range 2 auth seq id: 165
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LYS
pdbx struct sheet hbond.range 2 label seq id: 170

AA3
referenced by pdbx struct sheet hbond: 1,2,AA3
type: struct sheet
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
struct sheet.id: AA3
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AA3
referenced by struct sheet range: 2,AA3
referenced by struct sheet range: 1,AA3

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/1
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 1
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/2
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 2
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CD
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/3
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 3
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NE
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NE
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/4
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 4
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CZ
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CZ
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/5
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 5
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NH1
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NH1
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/6
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 6
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NH2
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 173
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NH2
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 178
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/7
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
pdbx unobs or zero occ atoms.id: 7
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: ASP
pdbx unobs or zero occ atoms.auth seq id: 177
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: ASP
pdbx unobs or zero occ atoms.label seq id: 182
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/8
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
pdbx unobs or zero occ atoms.id: 8
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: OD1
pdbx unobs or zero occ atoms.auth comp id: ASP
pdbx unobs or zero occ atoms.auth seq id: 177
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: OD1
pdbx unobs or zero occ atoms.label comp id: ASP
pdbx unobs or zero occ atoms.label seq id: 182
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/9
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
pdbx unobs or zero occ atoms.id: 9
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: OD2
pdbx unobs or zero occ atoms.auth comp id: ASP
pdbx unobs or zero occ atoms.auth seq id: 177
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: OD2
pdbx unobs or zero occ atoms.label comp id: ASP
pdbx unobs or zero occ atoms.label seq id: 182
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/10
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 10
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 248
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 253
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/11
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 11
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CD
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 248
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 253
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/12
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 12
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CE
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 248
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CE
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 253
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/13
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 13
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NZ
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 248
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NZ
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 253
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/14
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 14
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 264
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: GLN
pdbx unobs or zero occ atoms.label seq id: 269
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/15
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 15
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CD
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 264
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: GLN
pdbx unobs or zero occ atoms.label seq id: 269
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/16
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 16
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: OE1
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 264
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: OE1
pdbx unobs or zero occ atoms.label comp id: GLN
pdbx unobs or zero occ atoms.label seq id: 269
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/17
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 17
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NE2
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 264
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NE2
pdbx unobs or zero occ atoms.label comp id: GLN
pdbx unobs or zero occ atoms.label seq id: 269
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/18
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ atoms.id: 18
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: MET
pdbx unobs or zero occ atoms.auth seq id: 265
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: MET
pdbx unobs or zero occ atoms.label seq id: 270
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_atoms/19
type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ atoms.id: 19
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: SD
pdbx unobs or zero occ atoms.auth comp id: MET
pdbx unobs or zero occ atoms.auth seq id: 265
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: SD
pdbx unobs or zero occ atoms.label comp id: MET
pdbx unobs or zero occ atoms.label seq id: 270
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

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type: pdbx unobs or zero occ atoms
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ atoms.id: 20
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pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CE
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pdbx unobs or zero occ atoms.auth seq id: 265
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CE
pdbx unobs or zero occ atoms.label comp id: MET
pdbx unobs or zero occ atoms.label seq id: 270
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/1
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
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pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

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type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ALA
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pdbx unobs or zero occ residues.auth asym id: A
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pdbx unobs or zero occ residues.label asym id: A
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pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/3
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
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pdbx unobs or zero occ residues.label asym id: A
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pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/4
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
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pdbx unobs or zero occ residues.auth seq id: -1
pdbx unobs or zero occ residues.label asym id: A
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pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/5
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
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pdbx unobs or zero occ residues.pdb model num: 1
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pdbx unobs or zero occ residues.auth seq id: 0
pdbx unobs or zero occ residues.label asym id: A
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pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/6
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 6
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
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pdbx unobs or zero occ residues.auth seq id: 1
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 6
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/7
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 7
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
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pdbx unobs or zero occ residues.auth seq id: 2
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 7
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/8
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
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pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 3
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 8
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/9
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 9
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 4
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
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pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/10
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 10
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 178
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 183
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/11
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 11
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 179
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 184
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/12
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 12
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 180
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 185
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/13
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 13
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pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 181
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 186
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/14
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: TYR
pdbx unobs or zero occ residues.id: 14
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: TYR
pdbx unobs or zero occ residues.auth seq id: 182
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: TYR
pdbx unobs or zero occ residues.label seq id: 187
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/15
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 15
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 183
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 188
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/16
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 16
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 198
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 203
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/17
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 17
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
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pdbx unobs or zero occ residues.auth seq id: 261
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 266
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/18
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 18
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 262
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 267
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/19
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 19
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 263
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 268
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/20
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 20
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 353
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 358
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/21
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 21
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 354
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 359
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/22
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLN
pdbx unobs or zero occ residues.id: 22
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 355
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 360
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/23
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 23
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 356
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 361
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/24
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 24
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 357
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 362
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/25
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 25
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 358
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 363
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/26
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 26
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 359
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 364
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_unobs_or_zero_occ_residues/27
type: pdbx unobs or zero occ residues
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 27
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 360
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 365
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_validate_close_contact/1
type: pdbx validate close contact
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx validate close contact.id: 1
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: NZ
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: LYS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 53
pdbx validate close contact.auth seq id 2: 601
pdbx validate close contact.dist: 1.91

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_validate_torsion/1
type: pdbx validate torsion
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx validate torsion.id: 1
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ARG
pdbx validate torsion.auth seq id: 149
pdbx validate torsion.phi: 74.38
pdbx validate torsion.psi: -15.21

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_validate_torsion/2
type: pdbx validate torsion
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx validate torsion.id: 2
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ARG
pdbx validate torsion.auth seq id: 149
pdbx validate torsion.phi: 75.63
pdbx validate torsion.psi: -16.66

http://rdf.wwpdb.org/pdb/5WJJ/pdbx_validate_torsion/3
type: pdbx validate torsion
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
pdbx validate torsion.id: 3
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: LEU
pdbx validate torsion.auth seq id: 289
pdbx validate torsion.phi: -102.83
pdbx validate torsion.psi: 43.9

MR
type: phasing
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
phasing.method: MR

5WJJ,X-RAY DIFFRACTION
type: refine
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
refine.entry id: 5WJJ
refine.pdbx refine id: X-RAY DIFFRACTION
refine.b iso mean: 22.054
refine.aniso B11: -0.62
refine.aniso B12: 0
refine.aniso B13: 0
refine.aniso B22: 1.46
refine.aniso B23: 0
refine.aniso B33: -0.84
refine.correlation coeff fo to fc: 0.954
refine.correlation coeff fo to fc free: 0.932
refine.details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
refine.ls r factor r free: 0.23712
refine.ls r factor r work: 0.20033
refine.ls r factor obs: 0.20221
refine.ls d res high: 1.6
refine.ls d res low: 50
refine.ls number reflns r free: 2346
refine.ls number reflns obs: 44054
refine.ls percent reflns r free: 5.1
refine.ls percent reflns obs: 95.37
refine.overall SU b: 4.27
refine.overall SU ML: 0.076
refine.pdbx r free selection details: RANDOM
refine.pdbx diffrn id: 1
refine.pdbx ls cross valid method: THROUGHOUT
refine.pdbx method to determine struct: MOLECULAR REPLACEMENT
refine.pdbx overall ESU r: 0.105
refine.pdbx overall ESU r free: 0.105
refine.pdbx solvent ion probe radii: 0.8
refine.pdbx solvent shrinkage radii: 0.8
refine.pdbx solvent vdw probe radii: 1.2

1,X-RAY DIFFRACTION
type: refine hist
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine hist.cycle id: 1
refine hist.pdbx refine id: X-RAY DIFFRACTION
refine hist.d res high: 1.6
refine hist.d res low: 50
refine hist.number atoms solvent: 380
refine hist.number atoms total: 3126
refine hist.pdbx number atoms ligand: 34
refine hist.pdbx number atoms nucleic acid: 0
refine hist.pdbx number atoms protein: 2712

X-RAY DIFFRACTION,r bond refined d
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_refined_d
refine ls restr.dev ideal: 0.009
refine ls restr.dev ideal target: 0.019
refine ls restr.number: 2853

X-RAY DIFFRACTION,r bond other d
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_other_d
refine ls restr.dev ideal: 0.002
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 2689

X-RAY DIFFRACTION,r angle refined deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_refined_deg
refine ls restr.dev ideal: 1.322
refine ls restr.dev ideal target: 1.974
refine ls restr.number: 3887

X-RAY DIFFRACTION,r angle other deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_other_deg
refine ls restr.dev ideal: 0.885
refine ls restr.dev ideal target: 3
refine ls restr.number: 6182

X-RAY DIFFRACTION,r dihedral angle 1 deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_1_deg
refine ls restr.dev ideal: 5.073
refine ls restr.dev ideal target: 5
refine ls restr.number: 346

X-RAY DIFFRACTION,r dihedral angle 2 deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_2_deg
refine ls restr.dev ideal: 34.357
refine ls restr.dev ideal target: 23.897
refine ls restr.number: 136

X-RAY DIFFRACTION,r dihedral angle 3 deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_3_deg
refine ls restr.dev ideal: 12.533
refine ls restr.dev ideal target: 15
refine ls restr.number: 481

X-RAY DIFFRACTION,r dihedral angle 4 deg
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_4_deg
refine ls restr.dev ideal: 17.971
refine ls restr.dev ideal target: 15
refine ls restr.number: 19

X-RAY DIFFRACTION,r chiral restr
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_chiral_restr
refine ls restr.dev ideal: 0.074
refine ls restr.dev ideal target: 0.2
refine ls restr.number: 431

X-RAY DIFFRACTION,r gen planes refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_refined
refine ls restr.dev ideal: 0.006
refine ls restr.dev ideal target: 0.021
refine ls restr.number: 3211

X-RAY DIFFRACTION,r gen planes other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_other
refine ls restr.dev ideal: 0.002
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 654

X-RAY DIFFRACTION,r nbd refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_refined

X-RAY DIFFRACTION,r nbd other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_other

X-RAY DIFFRACTION,r nbtor refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_refined

X-RAY DIFFRACTION,r nbtor other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_other

X-RAY DIFFRACTION,r xyhbond nbd refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_refined

X-RAY DIFFRACTION,r xyhbond nbd other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_other

X-RAY DIFFRACTION,r metal ion refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_refined

X-RAY DIFFRACTION,r metal ion other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_other

X-RAY DIFFRACTION,r symmetry vdw refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_refined

X-RAY DIFFRACTION,r symmetry vdw other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_other

X-RAY DIFFRACTION,r symmetry hbond refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_refined

X-RAY DIFFRACTION,r symmetry hbond other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_other

X-RAY DIFFRACTION,r symmetry metal ion refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_refined

X-RAY DIFFRACTION,r symmetry metal ion other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_other

X-RAY DIFFRACTION,r mcbond it
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_it
refine ls restr.dev ideal: 0.542
refine ls restr.dev ideal target: 1.183
refine ls restr.number: 1360

X-RAY DIFFRACTION,r mcbond other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_other
refine ls restr.dev ideal: 0.542
refine ls restr.dev ideal target: 1.182
refine ls restr.number: 1359

X-RAY DIFFRACTION,r mcangle it
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_it
refine ls restr.dev ideal: 0.975
refine ls restr.dev ideal target: 1.768
refine ls restr.number: 1696

X-RAY DIFFRACTION,r mcangle other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_other
refine ls restr.dev ideal: 0.975
refine ls restr.dev ideal target: 1.769
refine ls restr.number: 1697

X-RAY DIFFRACTION,r scbond it
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_it
refine ls restr.dev ideal: 0.567
refine ls restr.dev ideal target: 1.264
refine ls restr.number: 1493

X-RAY DIFFRACTION,r scbond other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_other
refine ls restr.dev ideal: 0.534
refine ls restr.dev ideal target: 1.257
refine ls restr.number: 1456

X-RAY DIFFRACTION,r scangle it
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_it

X-RAY DIFFRACTION,r scangle other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_other
refine ls restr.dev ideal: 0.924
refine ls restr.dev ideal target: 1.857
refine ls restr.number: 2131

X-RAY DIFFRACTION,r long range B refined
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_refined
refine ls restr.dev ideal: 5.656
refine ls restr.dev ideal target: 11.351
refine ls restr.number: 3694

X-RAY DIFFRACTION,r long range B other
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_other
refine ls restr.dev ideal: 5.369
refine ls restr.dev ideal target: 10.069
refine ls restr.number: 3416

X-RAY DIFFRACTION,r rigid bond restr
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_rigid_bond_restr

X-RAY DIFFRACTION,r sphericity free
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_free

X-RAY DIFFRACTION,r sphericity bonded
type: refine ls restr
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_bonded

1.598,X-RAY DIFFRACTION
type: refine ls shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
refine ls shell.d res high: 1.598
refine ls shell.pdbx refine id: X-RAY DIFFRACTION
refine ls shell.r factor r free: 0.308
refine ls shell.r factor r work: 0.284
refine ls shell.d res low: 1.639
refine ls shell.number reflns r free: 100
refine ls shell.number reflns r work: 2013
refine ls shell.pdbx total number of bins used: 20
refine ls shell.percent reflns obs: 59.72

http://rdf.wwpdb.org/pdb/5WJJ/reflns/1
type: reflns
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
reflns.pdbx ordinal: 1
reflns.d resolution high: 1.6
reflns.d resolution low: 50.7
reflns.entry id: 5WJJ
reflns.number obs: 46461
reflns.pdbx rmerge i obs: 0.068
reflns.pdbx chi squared: 1.014
reflns.pdbx diffrn id: 1
reflns.pdbx net i over sigma i: 11.6
reflns.pdbx redundancy: 4.3
reflns.percent possible obs: 95.5

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/1
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 1
reflns shell.rmerge i obs: 0.428
reflns shell.d res high: 1.6
reflns shell.d res low: 1.64
reflns shell.pdbx chi squared: 0.979
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 2.6
reflns shell.percent possible all: 60

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/2
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 2
reflns shell.rmerge i obs: 0.441
reflns shell.d res high: 1.64
reflns shell.d res low: 1.68
reflns shell.pdbx chi squared: 1.01
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 3.2
reflns shell.percent possible all: 80.2

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/3
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 3
reflns shell.rmerge i obs: 0.394
reflns shell.d res high: 1.68
reflns shell.d res low: 1.72
reflns shell.pdbx chi squared: 1.042
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 3.7
reflns shell.percent possible all: 93.3

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/4
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 4
reflns shell.rmerge i obs: 0.329
reflns shell.d res high: 1.72
reflns shell.d res low: 1.77
reflns shell.pdbx chi squared: 0.985
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.2
reflns shell.percent possible all: 99.2

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/5
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 5
reflns shell.rmerge i obs: 0.278
reflns shell.d res high: 1.77
reflns shell.d res low: 1.83
reflns shell.pdbx chi squared: 1.025
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.5
reflns shell.percent possible all: 99.9

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/6
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 6
reflns shell.rmerge i obs: 0.214
reflns shell.d res high: 1.83
reflns shell.d res low: 1.9
reflns shell.pdbx chi squared: 1.016
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 99.9

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/7
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 7
reflns shell.rmerge i obs: 0.163
reflns shell.d res high: 1.9
reflns shell.d res low: 1.97
reflns shell.pdbx chi squared: 1.046
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/8
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 8
reflns shell.rmerge i obs: 0.122
reflns shell.d res high: 1.97
reflns shell.d res low: 2.06
reflns shell.pdbx chi squared: 1.015
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/9
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 9
reflns shell.rmerge i obs: 0.092
reflns shell.d res high: 2.06
reflns shell.d res low: 2.17
reflns shell.pdbx chi squared: 1.018
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/10
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 10
reflns shell.rmerge i obs: 0.079
reflns shell.d res high: 2.17
reflns shell.d res low: 2.31
reflns shell.pdbx chi squared: 1.002
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/11
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 11
reflns shell.rmerge i obs: 0.07
reflns shell.d res high: 2.31
reflns shell.d res low: 2.49
reflns shell.pdbx chi squared: 1.008
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/12
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 12
reflns shell.rmerge i obs: 0.067
reflns shell.d res high: 2.49
reflns shell.d res low: 2.74
reflns shell.pdbx chi squared: 1.002
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.6
reflns shell.percent possible all: 99.9

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/13
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 13
reflns shell.rmerge i obs: 0.068
reflns shell.d res high: 2.74
reflns shell.d res low: 3.13
reflns shell.pdbx chi squared: 1.016
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.4
reflns shell.percent possible all: 99.9

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/14
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 14
reflns shell.rmerge i obs: 0.055
reflns shell.d res high: 3.13
reflns shell.d res low: 3.95
reflns shell.pdbx chi squared: 1.055
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.3
reflns shell.percent possible all: 99.9

http://rdf.wwpdb.org/pdb/5WJJ/reflns_shell/15
type: reflns shell
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reflns shell.pdbx ordinal: 15
reflns shell.rmerge i obs: 0.034
reflns shell.d res high: 3.95
reflns shell.d res low: 50
reflns shell.pdbx chi squared: 0.971
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.3
reflns shell.percent possible all: 99.4

http://rdf.wwpdb.org/pdb/5WJJ/software/1
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 1
software.classification: refinement
software.name: REFMAC
software.version: 5.8.0135

http://rdf.wwpdb.org/pdb/5WJJ/software/2
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 2
software.classification: data collection
software.name: HKL-2000

http://rdf.wwpdb.org/pdb/5WJJ/software/3
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 3
software.classification: data scaling
software.name: HKL-2000

http://rdf.wwpdb.org/pdb/5WJJ/software/4
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 4
software.classification: phasing
software.name: MOLREP

http://rdf.wwpdb.org/pdb/5WJJ/software/5
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 5
software.classification: data extraction
software.name: PDB_EXTRACT
software.version: 3.22

http://rdf.wwpdb.org/pdb/5WJJ/software/6
type: software
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
software.pdbx ordinal: 6
software.classification: data reduction
software.name: HKL-2000

5WJJ
type: struct
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
struct.entry id: 5WJJ
struct.pdbx CASP flag: N
struct.title: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors

http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/B
type: struct asym
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/2
struct asym.id: B
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/5WJJ/struct_asym/C
type: struct asym
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/3
struct asym.id: C
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

HELX P1
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P1
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 61
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 66
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: MET
struct conf.end auth seq id: 78
struct conf.end label asym id: A
struct conf.end label comp id: MET
struct conf.end label seq id: 83
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA1
struct conf.pdbx PDB helix length: 18

HELX P
referenced by struct conf: HELX P1
referenced by struct conf: HELX P2
referenced by struct conf: HELX P3
referenced by struct conf: HELX P4
referenced by struct conf: HELX P5
referenced by struct conf: HELX P6
referenced by struct conf: HELX P7
referenced by struct conf: HELX P8
referenced by struct conf: HELX P9
referenced by struct conf: HELX P10
referenced by struct conf: HELX P11
referenced by struct conf: HELX P12
referenced by struct conf: HELX P13
referenced by struct conf: HELX P14
referenced by struct conf: HELX P15
referenced by struct conf: HELX P16
referenced by struct conf: HELX P17
referenced by struct conf: HELX P18
type: struct conf type
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
struct conf type.id: HELX_P

HELX P2
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P2
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 95
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 100
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: PHE
struct conf.end auth seq id: 99
struct conf.end label asym id: A
struct conf.end label comp id: PHE
struct conf.end label seq id: 104
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA2
struct conf.pdbx PDB helix length: 5

HELX P3
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P3
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 112
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 117
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 118
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 123
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA3
struct conf.pdbx PDB helix length: 7

HELX P4
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P4
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 123
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 128
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 144
struct conf.end label asym id: A
struct conf.end label comp id: ALA
struct conf.end label seq id: 149
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA4
struct conf.pdbx PDB helix length: 22

HELX P5
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P5
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 152
struct conf.beg label asym id: A
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 157
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: SER
struct conf.end auth seq id: 154
struct conf.end label asym id: A
struct conf.end label comp id: SER
struct conf.end label seq id: 159
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA5
struct conf.pdbx PDB helix length: 3

HELX P6
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P6
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 184
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 189
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 189
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 194
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA6
struct conf.pdbx PDB helix length: 6

HELX P7
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P7
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 190
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 195
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 195
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 200
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA7
struct conf.pdbx PDB helix length: 6

HELX P8
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P8
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 203
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 208
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 219
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 224
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA8
struct conf.pdbx PDB helix length: 17

HELX P9
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P9
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 227
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 232
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 240
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 245
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA9
struct conf.pdbx PDB helix length: 14

HELX P10
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P10
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 243
struct conf.beg label asym id: A
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 248
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 248
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 253
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB1
struct conf.pdbx PDB helix length: 6

HELX P11
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P11
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 252
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 257
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 260
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 265
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB2
struct conf.pdbx PDB helix length: 9

HELX P12
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P12
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 269
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 274
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 273
struct conf.end label asym id: A
struct conf.end label comp id: VAL
struct conf.end label seq id: 278
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB3
struct conf.pdbx PDB helix length: 5

HELX P13
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P13
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 278
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 283
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 289
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 294
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB4
struct conf.pdbx PDB helix length: 12

HELX P14
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P14
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 292
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 297
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 296
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 301
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB5
struct conf.pdbx PDB helix length: 5

HELX P15
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P15
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 298
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 303
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 304
struct conf.end label asym id: A
struct conf.end label comp id: ALA
struct conf.end label seq id: 309
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB6
struct conf.pdbx PDB helix length: 7

HELX P16
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P16
struct conf.beg auth asym id: A
struct conf.beg auth comp id: HIS
struct conf.beg auth seq id: 305
struct conf.beg label asym id: A
struct conf.beg label comp id: HIS
struct conf.beg label seq id: 310
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 309
struct conf.end label asym id: A
struct conf.end label comp id: ALA
struct conf.end label seq id: 314
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB7
struct conf.pdbx PDB helix length: 5

HELX P17
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P17
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLN
struct conf.beg auth seq id: 325
struct conf.beg label asym id: A
struct conf.beg label comp id: GLN
struct conf.beg label seq id: 330
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 330
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 335
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB8
struct conf.pdbx PDB helix length: 6

HELX P18
type: struct conf
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct conf type: HELX P
struct conf.id: HELX_P18
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 333
struct conf.beg label asym id: A
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 338
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: PHE
struct conf.end auth seq id: 348
struct conf.end label asym id: A
struct conf.end label comp id: PHE
struct conf.end label seq id: 353
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB9
struct conf.pdbx PDB helix length: 16

5WJJ
type: struct keywords
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
struct keywords.entry id: 5WJJ
struct keywords.pdbx keywords: Transferase/Transferase Inhibitor
struct keywords.text: Transferase-Transferase Inhibitor complex

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref/1
type: struct ref
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entity: http://rdf.wwpdb.org/pdb/5WJJ/entity/1
struct ref.id: 1
struct ref.db code: MK14_HUMAN
struct ref.db name: UNP
struct ref.entity id: 1
struct ref.pdbx align begin: 1
struct ref.pdbx db accession: Q16539
struct ref.pdbx seq one letter code: MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKH ENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNE DCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVA DPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
link to uniprot: uniprot:Q16539
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1

uniprot:Q16539

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
type: struct ref seq
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref/1
struct ref seq.align id: 1
struct ref seq.db align beg: 1
struct ref seq.db align end: 360
struct ref seq.pdbx PDB id code: 5WJJ
struct ref seq.pdbx auth seq align beg: 1
struct ref seq.pdbx auth seq align end: 360
struct ref seq.pdbx db accession: Q16539
struct ref seq.pdbx strand id: A
struct ref seq.ref id: 1
struct ref seq.seq align beg: 6
struct ref seq.seq align end: 365
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/7
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/1
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/2
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/3
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/4
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/5
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/6

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/1
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 1
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -4
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/2
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 2
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: ALA
struct ref seq dif.pdbx auth seq num: -3
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/3
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 3
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: MET
struct ref seq dif.pdbx auth seq num: -2
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 3

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/4
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 4
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -1
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 4

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/5
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 5
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 0
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 5

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/6
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 6
struct ref seq dif.align id: 1
struct ref seq dif.db mon id: CYS
struct ref seq dif.details: conflict
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 119
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.pdbx seq db seq num: 119
struct ref seq dif.seq num: 124

http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq_dif/7
type: struct ref seq dif
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5WJJ/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 7
struct ref seq dif.align id: 1
struct ref seq dif.db mon id: CYS
struct ref seq dif.details: conflict
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 162
struct ref seq dif.pdbx pdb id code: 5WJJ
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q16539
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.pdbx seq db seq num: 162
struct ref seq dif.seq num: 167

1,2,AA1
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA1
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA1
struct sheet order.sense: anti-parallel

1,2,AA2
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA2
struct sheet order.sense: anti-parallel

2,3,AA2
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: AA2
struct sheet order.sense: anti-parallel

3,4,AA2
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet order.range id 1: 3
struct sheet order.range id 2: 4
struct sheet order.sheet id: AA2
struct sheet order.sense: anti-parallel

4,5,AA2
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet order.range id 1: 4
struct sheet order.range id 2: 5
struct sheet order.sheet id: AA2
struct sheet order.sense: anti-parallel

1,2,AA3
type: struct sheet order
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA3
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA3
struct sheet order.sense: anti-parallel

1,AA1
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA1
struct sheet range.id: 1
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: PHE
struct sheet range.beg auth seq id: 8
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: PHE
struct sheet range.beg label seq id: 13
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 13
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 18

2,AA1
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA1
struct sheet range.id: 2
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: THR
struct sheet range.beg auth seq id: 16
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: THR
struct sheet range.beg label seq id: 21
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: PRO
struct sheet range.end auth seq id: 21
struct sheet range.end label asym id: A
struct sheet range.end label comp id: PRO
struct sheet range.end label seq id: 26

1,AA2
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet range.id: 1
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: TYR
struct sheet range.beg auth seq id: 24
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: TYR
struct sheet range.beg label seq id: 29
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: GLY
struct sheet range.end auth seq id: 33
struct sheet range.end label asym id: A
struct sheet range.end label comp id: GLY
struct sheet range.end label seq id: 38

2,AA2
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet range.id: 2
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: GLY
struct sheet range.beg auth seq id: 36
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: GLY
struct sheet range.beg label seq id: 41
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ASP
struct sheet range.end auth seq id: 43
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ASP
struct sheet range.end label seq id: 48

3,AA2
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet range.id: 3
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 48
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 53
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LYS
struct sheet range.end auth seq id: 54
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LYS
struct sheet range.end label seq id: 59

4,AA2
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet range.id: 4
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: TYR
struct sheet range.beg auth seq id: 103
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: TYR
struct sheet range.beg label seq id: 108
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: HIS
struct sheet range.end auth seq id: 107
struct sheet range.end label asym id: A
struct sheet range.end label comp id: HIS
struct sheet range.end label seq id: 112

5,AA2
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA2
struct sheet range.id: 5
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ASP
struct sheet range.beg auth seq id: 88
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ASP
struct sheet range.beg label seq id: 93
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: PHE
struct sheet range.end auth seq id: 90
struct sheet range.end label asym id: A
struct sheet range.end label comp id: PHE
struct sheet range.end label seq id: 95

1,AA3
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA3
struct sheet range.id: 1
struct sheet range.sheet id: AA3
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 156
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 161
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: VAL
struct sheet range.end auth seq id: 158
struct sheet range.end label asym id: A
struct sheet range.end label comp id: VAL
struct sheet range.end label seq id: 163

2,AA3
type: struct sheet range
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct sheet: AA3
struct sheet range.id: 2
struct sheet range.sheet id: AA3
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 164
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 169
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ILE
struct sheet range.end auth seq id: 166
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ILE
struct sheet range.end label seq id: 171

AC1
type: struct site
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
struct site.id: AC1
struct site.details: binding site for residue AQY A 501
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: AQY
struct site.pdbx auth seq id: 501
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 18
referenced by struct site gen: 18,AC1
referenced by struct site gen: 1,AC1
referenced by struct site gen: 2,AC1
referenced by struct site gen: 3,AC1
referenced by struct site gen: 4,AC1
referenced by struct site gen: 5,AC1
referenced by struct site gen: 6,AC1
referenced by struct site gen: 7,AC1
referenced by struct site gen: 8,AC1
referenced by struct site gen: 9,AC1
referenced by struct site gen: 10,AC1
referenced by struct site gen: 11,AC1
referenced by struct site gen: 12,AC1
referenced by struct site gen: 13,AC1
referenced by struct site gen: 14,AC1
referenced by struct site gen: 15,AC1
referenced by struct site gen: 16,AC1
referenced by struct site gen: 17,AC1

1,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 1
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: VAL
struct site gen.auth seq id: 30
struct site gen.label asym id: A
struct site gen.label comp id: VAL
struct site gen.label seq id: 35
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

2,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 2
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: TYR
struct site gen.auth seq id: 35
struct site gen.label asym id: A
struct site gen.label comp id: TYR
struct site gen.label seq id: 40
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

3,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 3
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: VAL
struct site gen.auth seq id: 38
struct site gen.label asym id: A
struct site gen.label comp id: VAL
struct site gen.label seq id: 43
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

4,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 4
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 51
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 56
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

5,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 5
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 53
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 58
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

6,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 6
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 75
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 80
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

7,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 7
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 104
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 109
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

8,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 8
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: VAL
struct site gen.auth seq id: 105
struct site gen.label asym id: A
struct site gen.label comp id: VAL
struct site gen.label seq id: 110
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

9,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 9
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: THR
struct site gen.auth seq id: 106
struct site gen.label asym id: A
struct site gen.label comp id: THR
struct site gen.label seq id: 111
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

10,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 10
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HIS
struct site gen.auth seq id: 107
struct site gen.label asym id: A
struct site gen.label comp id: HIS
struct site gen.label seq id: 112
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

11,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 11
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: MET
struct site gen.auth seq id: 109
struct site gen.label asym id: A
struct site gen.label comp id: MET
struct site gen.label seq id: 114
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

12,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 12
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: PHE
struct site gen.auth seq id: 169
struct site gen.label asym id: A
struct site gen.label comp id: PHE
struct site gen.label seq id: 174
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

13,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 13
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: GLY
struct site gen.auth seq id: 170
struct site gen.label asym id: A
struct site gen.label comp id: GLY
struct site gen.label seq id: 175
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

14,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 14
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 171
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 176
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

15,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 15
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 172
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 177
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

16,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 16
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HIS
struct site gen.auth seq id: 174
struct site gen.label asym id: A
struct site gen.label comp id: HIS
struct site gen.label seq id: 179
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

17,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 17
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 601
struct site gen.label asym id: C
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

18,AC1
type: struct site gen
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to struct site: AC1
struct site gen.id: 18
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 611
struct site gen.label asym id: C
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 18
struct site gen.symmetry: 1_555

5WJJ
type: symmetry
of datablock: Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]pyridazine-based p38 MAP Kinase Inhibitors
reference to entry: 5WJJ
symmetry.entry id: 5WJJ
symmetry.int tables number: 19
symmetry.space group name H-M: P 21 21 21