Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants.

Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5
EF1-EF2 domains (UNP residues 7024-7108)

620 kDa actin-binding protein, ABP620, Actin cross-linking family protein 7, Macrophin-1, Trabeculin-alpha, ACF7

GPGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYI
DYYEFVAALHP

National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS)

Chain C is not an independent entity, but has been modeled as a separate chain because there is insufficient electron density to determine whether it is contiguous with chain A or chain B.

chain 'A' and (resid 7019 through 7051 )

chain 'A' and (resid 7052 through 7076 )

chain 'A' and (resid 7077 through 7106 )

chain 'C' and (resid 7116 through 7145 )

chain 'C' and (resid 7146 through 7160 )

chain 'C' and (resid 7161 through 7189 )

chain 'B' and (resid 7016 through 7025 )

chain 'B' and (resid 7026 through 7040 )

chain 'B' and (resid 7041 through 7051 )

chain 'B' and (resid 7052 through 7071 )

chain 'B' and (resid 7072 through 7087 )

chain 'B' and (resid 7088 through 7106 )

Spectraplakin, EF-Hand, microtubule binding, GAS2, PROTEIN BINDING

ANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFV
AALHP