Crystal Structure of The Receptor-binding Domain of Botulinum Neurotoxin Type HA

Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H.

GPLGSMELKYNCILNIKYEMDRDKLVDSSGYRSRINIGTGVKFSEIDKNQVQLSNLESSKIEVILNNGVIYNSMYENFST
SFWIRIPKYFRNINNEYKIISCMQNNSGWEVSLNFSNMNSKIIWTLQDTEGIKKTVVFQYTQNINISDYINRWIFVTITN
NRLSNSKIYINGRLINEESISDLGNIHASNNIMFKLDGCRDPHRYIWIKYFNLFDKELNKKEIKDLYDNQSNSGILKDFW
GDYLQYDKPYYMLNLYDPNKYLDVNNVGIRGYMYLKGPRGRIVTTNIYLNSTLYMGTKFIIKKYASGNKDNIVRNNDRVY
INVVVKNKEYRLATNASQAGVEKILSAVEIPDVGNLSQVVVMKSENDQGIRNKCKMNLQDNNGNDIGFIGFHQFNNIAKL
VASNWYNRQIGKASRTFGCSWEFIPVDDGWGESSL

100 mM sodium acetate, pH 4.2; 20% Polyethylene glyco (PEG) 3,350

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

CHAIN 'A' AND (RESID 1058 THROUGH 1158 )

CHAIN 'A' AND (RESID 1159 THROUGH 1205 )

CHAIN 'A' AND (RESID 1206 THROUGH 1288 )

CHAIN 'B' AND (RESID 1058 THROUGH 1158 )

CHAIN 'B' AND (RESID 1159 THROUGH 1205 )

CHAIN 'B' AND (RESID 1206 THROUGH 1288 )

botulinum neurotoxin (BoNT); BoNT/HA; BoNT/H; BoNT/FA; receptor-binding domain; host receptor; neutralizing antibody, TOXIN