RNA primer-template complex with guanosine dinucleotide p(5')G(3')p(5')G ligand
[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
0.05 M Magnesium chloride, 0.1 M HEPES sodium pH 7.5, 2% v/v Polyethylene glycol 400, 2.0 M Ammonium sulfate
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS