Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7)

Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

NPP-7,Alkaline sphingomyelin phosphodiesterase,Intestinal alkaline sphingomyelinase,Alk-SMase

DRHHHHHHKLAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENH
GVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETE
WRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTT
VDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLL
MYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLP
MLHTESALPPDGRPTLLPKGRS

Canadian Institutes of Health Research (CIHR)

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E.C.3.1.4.12)

sphingomyelinase, sphingomyelin, HYDROLASE

APVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNT
TSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMA
WFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVE
FHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIH
GRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPP
DGRPTLLPKGRS