Crystal structure of a peptide deformylase from Burkholderia multivorans in complex with actinonin

Seattle Structural Genomics Center for Infectious Disease (SSGCID)

2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEPTANOIC ACID [1-(2-HYDROXYMETHYL-PYRROLIDINE-1-CARBONYL)-2-METHYL-PROPYL]-AMIDE

MAHHHHHHMIREILKMGDPRLLEVARPVDRFDTPELHEIVADMFETMHHANGAGLAAPQIGIGLQIIIFGFGSNDRYPDA
PPVPETVLINPKLEYMPPDMEEGWEGCLSVPGMRGVVSRYAKVRYSGFDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYP
MRITDFTRFGFTEVLFPGLDPAADD

Burkholderia multivorans (strain ATCC 17616 / 249)

MCSG1 F4 (272591f4): 40% (v/v) PEG 400, 200 mM Magnesium chloride, 100 mM Sodium citrate:citric acid pH 5.5, 3 mM actinonin; direct cryo; puck kur4-4

Seattle Structural Genomics Center for Infectious Disease
NIAID, National Institute of Allergy and Infectious Diseases

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

SSGCID, peptide deformylase, actinonin, Burkholderia multivorans, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, HYDROLASE, hydrolase-antibiotic complex

MIREILKMGDPRLLEVARPVDRFDTPELHEIVADMFETMHHANGAGLAAPQIGIGLQIIIFGFGSNDRYPDAPPVPETVL
INPKLEYMPPDMEEGWEGCLSVPGMRGVVSRYAKVRYSGFDQFGAKIDRVAEGFHARVVQHEYDHLIGKLYPMRITDFTR
FGFTEVLFPGLDPAADD