HumRadA1 soaked with 0.2 mM indazole in 10% DMSO

Optimisation of crystal forms for structure-guided drug discovery

MATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVMWIDTENTFRPERIREIA
QNRGLDPDEVLKHIAYARAFNSNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLA
DLHRLANLYDIAVFVTNQVQANGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED

Evaluation of the effect of ligand soaking time and concentration for fragment-based drug discovery

RAD51, RadA, inhibition, FBDD, PPI, DNA BINDING PROTEIN