Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-(3,4-dichlorophenyl)sulfonylurea

Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA

MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSND
LVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNL
VAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILG
SPDDVLEFLKVYEKHSAQ

0.1M HEPES pH 7.0, 0.1M AMMONIUM ACETATE, 12%-25% PEG 3350

Fructose-1,6-bisphosphatase 1 with inhibitors
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with allosteric inhibitors

D3R docking, HYDROLASE-HYDROLASE inhibitor complex

(chain A and (resid 9 through 61 or resid 72 through 139 or resid 141 through 335))

(chain B and (resid 9 through 139 or resid 141 through 335))

(chain C and (resid 9 through 139 or resid 141 through 335))

(chain D and (resid 9 through 139 or resid 141 through 335))

(chain E and (resid 9 through 61 or resid 72 through 139 or resid 141 through 335))

(chain F and (resid 9 through 139 or resid 141 through 335))

(chain G and (resid 9 through 139 or resid 141 through 335))

(chain H and (resid 9 through 139 or resid 141 through 335))