Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor [5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid

{5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}phosphonic acid

Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA

MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSND
LVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNL
VAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILG
SPDDVLEFLKVYEKHSAQ

0.1M HEPES pH 7.0, 0.1M AMMONIUM ACETATE, 12% PEG 3350

Fructose-1,6-bisphosphatase 1 with inhibitors
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with allosteric inhibitors

D3R docking, HYDROLASE-HYDROLASE INHIBITOR complex

(chain A and (resid 9 through 61 or resid 72 through 139 or resid 141 through 156 or resid 158 through 335))

(chain B and (resid 9 through 139 or resid 141 through 156 or resid 158 through 335))

(chain C and (resid 9 through 61 or resid 72 through 139 or resid 141 through 156 or resid 158 through 335))

(chain D and (resid 9 through 139 or resid 141 through 156 or resid 158 through 335))