Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Imidazolidine-2,4-dione (Hydantoin)

AMPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSW
FKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD

0.1 M sodium acetate pH 4.6, 15 %(W/V) PEG 20000

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Teratogenicity, Protein degradation, Substrate recognition, Ubiquitin ligase, UNKNOWN FUNCTION

MPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWF
KGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD