Extracellular domain of human CD83 - trigonal crystal form
Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.
The first four residues (GSPG) are non-native residues of the linker which remains after the GST-tag was cleaved off. The first three and last four residues as well as the central region were not visible in the electron density maps.
hCD83,B-cell activation protein,Cell surface protein HB15
GSPGTPEVKVASSEDVDLPCTAPWDPQVPYTVSWVKLLEGGEERMETPQEDHLRGQHYHQKGQNGSFDAPNERPYSLKIR NTTSSNSGTYRCTLQDPDGQRNLSGKVILRVTGSPA
0.4 microliter protein (39 mg/ml in 50 mM Tris-HCl (pH 8.0) buffer) were mixed with 0.2 microliter reservoir solution (1 M ammonium sulfate, 0.1 M HEPES (pH 7.0), 0.5% w/v polyethylene glycol (PEG) 8000) and equilibrated against 70 microliter of reservoir solution
Dendritic cell, receptor, immunoglobulin, immune system
TPEVKVACSEDVDLPCTAPWDPQVPYTVSWVKLLEGGEERMETPQEDHLRGQHYHQKGQNGSFDAPNERPYSLKIRNTTS CNSGTYRCTLQDPDGQRNLSGKVILRVTGCPA