D-GLYCERO-D-MANNOPYRANOSE-7-PHOSPHATE; 7-O-phosphono-D-glycero-alpha-D-manno-heptose; 7-O-phosphono-D-glycero-D-manno-heptose; 7-O-phosphono-D-glycero-manno-heptose

A half-site multimeric enzyme achieves its cooperativity without conformational changes.

MENRELTYITNSIAEAQRVMAAMLADERLLATVRKVADACIASIAQGGKVLLAGNGGSAADAQHIAGQFVSRFAFDRPGL
PAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNEGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELC
DLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ

untagged GmhA 10 mg per mL
0.1 M Na Acetate, pH 4.6, 8% PEG 4000

Biotechnology and Biological Sciences Research Council

Cooperativity, enzyme kinetics, hydrogen bonds, molecular modelling, quantum mechanics, isomerase

MENRELTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGL
PAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNEGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELC
DLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ