EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
type: datablock
alternative label: 5HG8
link to mmcif: 5HG8.cif.gz
link to pdbml: 5HG8.xml.gz
link to pdbml noatom: 5HG8-noatom.xml.gz
link to pdbml extatom: 5HG8-extatom.xml.gz
link to doi: doi:10.2210/pdb5HG8/pdb
datablock name: 5HG8-noatom
has atom sites category: atom sitesCategory
has atom type category: atom typeCategory
has audit author category: audit authorCategory
has audit conform category: audit conformCategory
has cell category: cellCategory
has chem comp category: chem compCategory
has chem comp atom category: chem comp atomCategory
has chem comp bond category: chem comp bondCategory
has citation category: citationCategory
has citation author category: citation authorCategory
has database 2 category: database 2Category
has database PDB matrix category: database PDB matrixCategory
has diffrn category: diffrnCategory
has diffrn detector category: diffrn detectorCategory
has diffrn radiation category: diffrn radiationCategory
has diffrn radiation wavelength category: diffrn radiation wavelengthCategory
has diffrn source category: diffrn sourceCategory
has entity category: entityCategory
has entity name com category: entity name comCategory
has entity poly category: entity polyCategory
has entity poly seq category: entity poly seqCategory
has entity src gen category: entity src genCategory
has entry category: entryCategory
has exptl category: exptlCategory
has exptl crystal category: exptl crystalCategory
has exptl crystal grow category: exptl crystal growCategory
has pdbx audit revision category category: pdbx audit revision categoryCategory
has pdbx audit revision details category: pdbx audit revision detailsCategory
has pdbx audit revision group category: pdbx audit revision groupCategory
has pdbx audit revision history category: pdbx audit revision historyCategory
has pdbx audit revision item category: pdbx audit revision itemCategory
has pdbx database related category: pdbx database relatedCategory
has pdbx database status category: pdbx database statusCategory
has pdbx entity nonpoly category: pdbx entity nonpolyCategory
has pdbx entry details category: pdbx entry detailsCategory
has pdbx nonpoly scheme category: pdbx nonpoly schemeCategory
has pdbx poly seq scheme category: pdbx poly seq schemeCategory
has pdbx refine category: pdbx refineCategory
has pdbx struct assembly category: pdbx struct assemblyCategory
has pdbx struct assembly gen category: pdbx struct assembly genCategory
has pdbx struct oper list category: pdbx struct oper listCategory
has pdbx struct sheet hbond category: pdbx struct sheet hbondCategory
has pdbx unobs or zero occ residues category: pdbx unobs or zero occ residuesCategory
has pdbx validate torsion category: pdbx validate torsionCategory
has pdbx xplor file category: pdbx xplor fileCategory
has refine category: refineCategory
has refine analyze category: refine analyzeCategory
has refine hist category: refine histCategory
has refine ls restr category: refine ls restrCategory
has refine ls shell category: refine ls shellCategory
has reflns category: reflnsCategory
has reflns shell category: reflns shellCategory
has software category: softwareCategory
has struct category: structCategory
has struct asym category: struct asymCategory
has struct conf category: struct confCategory
has struct conf type category: struct conf typeCategory
has struct conn category: struct connCategory
has struct conn type category: struct conn typeCategory
has struct keywords category: struct keywordsCategory
has struct ref category: struct refCategory
has struct ref seq category: struct ref seqCategory
has struct ref seq dif category: struct ref seq difCategory
has struct sheet category: struct sheetCategory
has struct sheet order category: struct sheet orderCategory
has struct sheet range category: struct sheet rangeCategory
has struct site category: struct siteCategory
has struct site gen category: struct site genCategory
has symmetry category: symmetryCategory

5HG8
type: atom sites
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
atom sites.entry id: 5HG8
atom sites.fract transf matrix11: 0.025043
atom sites.fract transf matrix12: 0
atom sites.fract transf matrix13: 0
atom sites.fract transf matrix21: 0
atom sites.fract transf matrix22: 0.014341
atom sites.fract transf matrix23: 0
atom sites.fract transf matrix31: 0
atom sites.fract transf matrix32: 0
atom sites.fract transf matrix33: 0.009041
atom sites.fract transf vector1: 0
atom sites.fract transf vector2: 0
atom sites.fract transf vector3: 0

5HG8
referenced by atom sites: 5HG8
referenced by cell: 5HG8
referenced by database PDB matrix: 5HG8
type: entry
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entry.id: 5HG8
referenced by exptl: 5HG8,X-RAY DIFFRACTION
referenced by refine: 5HG8,X-RAY DIFFRACTION
referenced by refine analyze: 5HG8,X-RAY DIFFRACTION
referenced by reflns: http://rdf.wwpdb.org/pdb/5HG8/reflns/1
referenced by struct: 5HG8
referenced by struct keywords: 5HG8
referenced by symmetry: 5HG8
referenced by pdbx database status: 5HG8
referenced by pdbx refine: 5HG8,X-RAY DIFFRACTION
referenced by pdbx entry details: 5HG8

http://rdf.wwpdb.org/pdb/5HG8/atom_type/C
type: atom type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
atom type.symbol: C

http://rdf.wwpdb.org/pdb/5HG8/atom_type/N
type: atom type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
atom type.symbol: N

http://rdf.wwpdb.org/pdb/5HG8/atom_type/O
type: atom type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
atom type.symbol: O

http://rdf.wwpdb.org/pdb/5HG8/atom_type/S
type: atom type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
atom type.symbol: S

http://rdf.wwpdb.org/pdb/5HG8/audit_author/1
type: audit author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
audit author.pdbx ordinal: 1
audit author.name: Gajiwala, K.S.

mmcif pdbx.dic,5.387
type: audit conform
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
audit conform.dict name: mmcif_pdbx.dic
audit conform.dict version: 5.387
audit conform.dict location: http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic

5HG8
type: cell
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
cell.entry id: 5HG8
cell.z PDB: 4
cell.angle alpha: 90
cell.angle beta: 90
cell.angle gamma: 90
cell.length a: 39.932
cell.length b: 69.73
cell.length c: 110.61

http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: 634
chem comp.formula: C19 H19 N7 O2
chem comp.formula weight: 377.4
chem comp.name: N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide
chem comp.pdbx synonyms: Bound form of N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.type: non-polymer
link to chem comp: http://rdf.wwpdb.org/cc/634
referenced by chem comp atom: H19,634
referenced by chem comp bond: C27,H19,634
referenced by chem comp atom: C4,634
referenced by chem comp atom: C5,634
referenced by chem comp atom: C8,634
referenced by chem comp atom: C13,634
referenced by chem comp atom: C15,634
referenced by chem comp atom: C20,634
referenced by chem comp atom: C21,634
referenced by chem comp atom: C24,634
referenced by chem comp atom: C28,634
referenced by chem comp atom: C1,634
referenced by chem comp atom: N2,634
referenced by chem comp atom: C3,634
referenced by chem comp atom: N6,634
referenced by chem comp atom: N7,634
referenced by chem comp atom: C9,634
referenced by chem comp atom: O10,634
referenced by chem comp atom: C11,634
referenced by chem comp atom: C12,634
referenced by chem comp atom: C14,634
referenced by chem comp atom: C16,634
referenced by chem comp atom: N17,634
referenced by chem comp atom: C18,634
referenced by chem comp atom: O19,634
referenced by chem comp atom: N22,634
referenced by chem comp atom: C23,634
referenced by chem comp atom: N25,634
referenced by chem comp atom: N26,634
referenced by chem comp atom: C27,634
referenced by chem comp atom: H1,634
referenced by chem comp atom: H2,634
referenced by chem comp atom: H3,634
referenced by chem comp atom: H4,634
referenced by chem comp atom: H5,634
referenced by chem comp atom: H6,634
referenced by chem comp atom: H7,634
referenced by chem comp atom: H8,634
referenced by chem comp atom: H9,634
referenced by chem comp atom: H10,634
referenced by chem comp atom: H11,634
referenced by chem comp atom: H12,634
referenced by chem comp atom: H13,634
referenced by chem comp atom: H14,634
referenced by chem comp atom: H15,634
referenced by chem comp atom: H16,634
referenced by chem comp atom: H17,634
referenced by chem comp atom: H18,634
referenced by chem comp bond: N7,C8,634
referenced by chem comp bond: N7,C5,634
referenced by chem comp bond: C8,C9,634
referenced by chem comp bond: C12,C13,634
referenced by chem comp bond: C12,C11,634
referenced by chem comp bond: C5,N6,634
referenced by chem comp bond: C5,C4,634
referenced by chem comp bond: N6,C1,634
referenced by chem comp bond: C9,C4,634
referenced by chem comp bond: C4,C3,634
referenced by chem comp bond: C1,N22,634
referenced by chem comp bond: C1,N2,634
referenced by chem comp bond: N22,C23,634
referenced by chem comp bond: C3,N2,634
referenced by chem comp bond: C3,O10,634
referenced by chem comp bond: C13,C14,634
referenced by chem comp bond: C23,C27,634
referenced by chem comp bond: C23,C24,634
referenced by chem comp bond: O10,C11,634
referenced by chem comp bond: C27,N26,634
referenced by chem comp bond: C24,N25,634
referenced by chem comp bond: N26,N25,634
referenced by chem comp bond: N25,C28,634

ALA
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: ALA
chem comp.formula: C3 H7 N O2
chem comp.formula weight: 89.093
chem comp.mon nstd flag: y
chem comp.name: ALANINE
chem comp.type: L-peptide linking
link to chem comp: ALA
referenced by chem comp atom: HXT,ALA
referenced by chem comp bond: OXT,HXT,ALA
referenced by entity poly seq: 1,ALA,320
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/20
referenced by chem comp atom: N,ALA
referenced by chem comp atom: CA,ALA
referenced by chem comp atom: C,ALA
referenced by chem comp atom: O,ALA
referenced by chem comp atom: CB,ALA
referenced by chem comp atom: OXT,ALA
referenced by chem comp atom: H,ALA
referenced by chem comp atom: H2,ALA
referenced by chem comp atom: HA,ALA
referenced by chem comp atom: HB1,ALA
referenced by chem comp atom: HB2,ALA
referenced by chem comp atom: HB3,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: C,O,ALA
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA
referenced by chem comp bond: CB,HB3,ALA
referenced by entity poly seq: 1,ALA,5
referenced by entity poly seq: 1,ALA,9
referenced by entity poly seq: 1,ALA,29
referenced by entity poly seq: 1,ALA,50
referenced by entity poly seq: 1,ALA,57
referenced by entity poly seq: 1,ALA,62
referenced by entity poly seq: 1,ALA,70
referenced by entity poly seq: 1,ALA,74
referenced by entity poly seq: 1,ALA,129
referenced by entity poly seq: 1,ALA,146
referenced by entity poly seq: 1,ALA,147
referenced by entity poly seq: 1,ALA,166
referenced by entity poly seq: 1,ALA,171
referenced by entity poly seq: 1,ALA,178
referenced by entity poly seq: 1,ALA,189
referenced by entity poly seq: 1,ALA,227
referenced by entity poly seq: 1,ALA,262
referenced by entity poly seq: 1,ALA,279
referenced by entity poly seq: 1,ALA,307
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/5
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/7

ARG
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: ARG
chem comp.formula: C6 H15 N4 O2 1
chem comp.formula weight: 175.209
chem comp.mon nstd flag: y
chem comp.name: ARGININE
chem comp.type: L-peptide linking
link to chem comp: ARG
referenced by chem comp atom: HXT,ARG
referenced by chem comp bond: OXT,HXT,ARG
referenced by entity poly seq: 1,ARG,306
referenced by chem comp atom: N,ARG
referenced by chem comp atom: CA,ARG
referenced by chem comp atom: C,ARG
referenced by chem comp atom: O,ARG
referenced by chem comp atom: CB,ARG
referenced by chem comp atom: CG,ARG
referenced by chem comp atom: CD,ARG
referenced by chem comp atom: NE,ARG
referenced by chem comp atom: CZ,ARG
referenced by chem comp atom: NH1,ARG
referenced by chem comp atom: NH2,ARG
referenced by chem comp atom: OXT,ARG
referenced by chem comp atom: H,ARG
referenced by chem comp atom: H2,ARG
referenced by chem comp atom: HA,ARG
referenced by chem comp atom: HB2,ARG
referenced by chem comp atom: HB3,ARG
referenced by chem comp atom: HG2,ARG
referenced by chem comp atom: HG3,ARG
referenced by chem comp atom: HD2,ARG
referenced by chem comp atom: HD3,ARG
referenced by chem comp atom: HE,ARG
referenced by chem comp atom: HH11,ARG
referenced by chem comp atom: HH12,ARG
referenced by chem comp atom: HH21,ARG
referenced by chem comp atom: HH22,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: C,O,ARG
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH1,HH11,ARG
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: NH2,HH21,ARG
referenced by chem comp bond: NH2,HH22,ARG
referenced by entity poly seq: 1,ARG,12
referenced by entity poly seq: 1,ARG,55
referenced by entity poly seq: 1,ARG,83
referenced by entity poly seq: 1,ARG,110
referenced by entity poly seq: 1,ARG,138
referenced by entity poly seq: 1,ARG,139
referenced by entity poly seq: 1,ARG,143
referenced by entity poly seq: 1,ARG,148
referenced by entity poly seq: 1,ARG,165
referenced by entity poly seq: 1,ARG,196
referenced by entity poly seq: 1,ARG,239
referenced by entity poly seq: 1,ARG,255
referenced by entity poly seq: 1,ARG,265
referenced by entity poly seq: 1,ARG,269
referenced by entity poly seq: 1,ARG,280
referenced by entity poly seq: 1,ARG,284
referenced by entity poly seq: 1,ARG,293

ASN
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: ASN
chem comp.formula: C4 H8 N2 O3
chem comp.formula weight: 132.118
chem comp.mon nstd flag: y
chem comp.name: ASPARAGINE
chem comp.type: L-peptide linking
link to chem comp: ASN
referenced by chem comp atom: HXT,ASN
referenced by chem comp bond: OXT,HXT,ASN
referenced by entity poly seq: 1,ASN,303
referenced by chem comp atom: N,ASN
referenced by chem comp atom: CA,ASN
referenced by chem comp atom: C,ASN
referenced by chem comp atom: O,ASN
referenced by chem comp atom: CB,ASN
referenced by chem comp atom: CG,ASN
referenced by chem comp atom: OD1,ASN
referenced by chem comp atom: ND2,ASN
referenced by chem comp atom: OXT,ASN
referenced by chem comp atom: H,ASN
referenced by chem comp atom: H2,ASN
referenced by chem comp atom: HA,ASN
referenced by chem comp atom: HB2,ASN
referenced by chem comp atom: HB3,ASN
referenced by chem comp atom: HD21,ASN
referenced by chem comp atom: HD22,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: C,O,ASN
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CG,OD1,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN
referenced by chem comp bond: ND2,HD22,ASN
referenced by entity poly seq: 1,ASN,7
referenced by entity poly seq: 1,ASN,63
referenced by entity poly seq: 1,ASN,78
referenced by entity poly seq: 1,ASN,115
referenced by entity poly seq: 1,ASN,123
referenced by entity poly seq: 1,ASN,133
referenced by entity poly seq: 1,ASN,149

ASP
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: ASP
chem comp.formula: C4 H7 N O4
chem comp.formula weight: 133.103
chem comp.mon nstd flag: y
chem comp.name: ASPARTIC ACID
chem comp.type: L-peptide linking
link to chem comp: ASP
referenced by chem comp atom: HXT,ASP
referenced by chem comp bond: OXT,HXT,ASP
referenced by entity poly seq: 1,ASP,321
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/21
referenced by chem comp atom: N,ASP
referenced by chem comp atom: CA,ASP
referenced by chem comp atom: C,ASP
referenced by chem comp atom: O,ASP
referenced by chem comp atom: CB,ASP
referenced by chem comp atom: CG,ASP
referenced by chem comp atom: OD1,ASP
referenced by chem comp atom: OD2,ASP
referenced by chem comp atom: OXT,ASP
referenced by chem comp atom: H,ASP
referenced by chem comp atom: H2,ASP
referenced by chem comp atom: HA,ASP
referenced by chem comp atom: HB2,ASP
referenced by chem comp atom: HB3,ASP
referenced by chem comp atom: HD2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: C,O,ASP
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CG,OD1,ASP
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: OD2,HD2,ASP
referenced by entity poly seq: 1,ASP,68
referenced by entity poly seq: 1,ASP,77
referenced by entity poly seq: 1,ASP,107
referenced by entity poly seq: 1,ASP,114
referenced by entity poly seq: 1,ASP,137
referenced by entity poly seq: 1,ASP,144
referenced by entity poly seq: 1,ASP,162
referenced by entity poly seq: 1,ASP,203
referenced by entity poly seq: 1,ASP,223
referenced by entity poly seq: 1,ASP,249
referenced by entity poly seq: 1,ASP,261
referenced by entity poly seq: 1,ASP,263
referenced by entity poly seq: 1,ASP,281
referenced by entity poly seq: 1,ASP,291
referenced by entity poly seq: 1,ASP,301
referenced by entity poly seq: 1,ASP,310
referenced by entity poly seq: 1,ASP,313
referenced by entity poly seq: 1,ASP,315
referenced by entity poly seq: 1,ASP,316
referenced by entity poly seq: 1,ASP,319
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/10
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/13
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/15
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/16
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/19

CYS
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: CYS
chem comp.formula: C3 H7 N O2 S
chem comp.formula weight: 121.158
chem comp.mon nstd flag: y
chem comp.name: CYSTEINE
chem comp.type: L-peptide linking
link to chem comp: CYS
referenced by chem comp atom: HXT,CYS
referenced by chem comp bond: OXT,HXT,CYS
referenced by entity poly seq: 1,CYS,257
referenced by chem comp atom: N,CYS
referenced by chem comp atom: CA,CYS
referenced by chem comp atom: C,CYS
referenced by chem comp atom: O,CYS
referenced by chem comp atom: CB,CYS
referenced by chem comp atom: SG,CYS
referenced by chem comp atom: OXT,CYS
referenced by chem comp atom: H,CYS
referenced by chem comp atom: H2,CYS
referenced by chem comp atom: HA,CYS
referenced by chem comp atom: HB2,CYS
referenced by chem comp atom: HB3,CYS
referenced by chem comp atom: HG,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: C,O,CYS
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: SG,HG,CYS
referenced by entity poly seq: 1,CYS,82
referenced by entity poly seq: 1,CYS,88
referenced by entity poly seq: 1,CYS,104
referenced by entity poly seq: 1,CYS,125
referenced by entity poly seq: 1,CYS,246

GLN
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: GLN
chem comp.formula: C5 H10 N2 O3
chem comp.formula weight: 146.144
chem comp.mon nstd flag: y
chem comp.name: GLUTAMINE
chem comp.type: L-peptide linking
link to chem comp: GLN
referenced by chem comp atom: HXT,GLN
referenced by chem comp bond: OXT,HXT,GLN
referenced by entity poly seq: 1,GLN,328
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/28
referenced by chem comp atom: N,GLN
referenced by chem comp atom: CA,GLN
referenced by chem comp atom: C,GLN
referenced by chem comp atom: O,GLN
referenced by chem comp atom: CB,GLN
referenced by chem comp atom: CG,GLN
referenced by chem comp atom: CD,GLN
referenced by chem comp atom: OE1,GLN
referenced by chem comp atom: NE2,GLN
referenced by chem comp atom: OXT,GLN
referenced by chem comp atom: H,GLN
referenced by chem comp atom: H2,GLN
referenced by chem comp atom: HA,GLN
referenced by chem comp atom: HB2,GLN
referenced by chem comp atom: HB3,GLN
referenced by chem comp atom: HG2,GLN
referenced by chem comp atom: HG3,GLN
referenced by chem comp atom: HE21,GLN
referenced by chem comp atom: HE22,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: C,O,GLN
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CD,OE1,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN
referenced by chem comp bond: NE2,HE22,GLN
referenced by entity poly seq: 1,GLN,8
referenced by entity poly seq: 1,GLN,94
referenced by entity poly seq: 1,GLN,98
referenced by entity poly seq: 1,GLN,119
referenced by entity poly seq: 1,GLN,127
referenced by entity poly seq: 1,GLN,156
referenced by entity poly seq: 1,GLN,201
referenced by entity poly seq: 1,GLN,242
referenced by entity poly seq: 1,GLN,283
referenced by entity poly seq: 1,GLN,289
referenced by entity poly seq: 1,GLN,327
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/27

GLU
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: GLU
chem comp.formula: C5 H9 N O4
chem comp.formula weight: 147.129
chem comp.mon nstd flag: y
chem comp.name: GLUTAMIC ACID
chem comp.type: L-peptide linking
link to chem comp: GLU
referenced by chem comp atom: HXT,GLU
referenced by chem comp bond: OXT,HXT,GLU
referenced by entity poly seq: 1,GLU,322
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/22
referenced by chem comp atom: N,GLU
referenced by chem comp atom: CA,GLU
referenced by chem comp atom: C,GLU
referenced by chem comp atom: O,GLU
referenced by chem comp atom: CB,GLU
referenced by chem comp atom: CG,GLU
referenced by chem comp atom: CD,GLU
referenced by chem comp atom: OE1,GLU
referenced by chem comp atom: OE2,GLU
referenced by chem comp atom: OXT,GLU
referenced by chem comp atom: H,GLU
referenced by chem comp atom: H2,GLU
referenced by chem comp atom: HA,GLU
referenced by chem comp atom: HB2,GLU
referenced by chem comp atom: HB3,GLU
referenced by chem comp atom: HG2,GLU
referenced by chem comp atom: HG3,GLU
referenced by chem comp atom: HE2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: C,O,GLU
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CD,OE1,GLU
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: OE2,HE2,GLU
referenced by entity poly seq: 1,GLU,4
referenced by entity poly seq: 1,GLU,16
referenced by entity poly seq: 1,GLU,18
referenced by entity poly seq: 1,GLU,41
referenced by entity poly seq: 1,GLU,43
referenced by entity poly seq: 1,GLU,53
referenced by entity poly seq: 1,GLU,56
referenced by entity poly seq: 1,GLU,65
referenced by entity poly seq: 1,GLU,69
referenced by entity poly seq: 1,GLU,111
referenced by entity poly seq: 1,GLU,136
referenced by entity poly seq: 1,GLU,172
referenced by entity poly seq: 1,GLU,173
referenced by entity poly seq: 1,GLU,175
referenced by entity poly seq: 1,GLU,179
referenced by entity poly seq: 1,GLU,191
referenced by entity poly seq: 1,GLU,213
referenced by entity poly seq: 1,GLU,229
referenced by entity poly seq: 1,GLU,235
referenced by entity poly seq: 1,GLU,238
referenced by entity poly seq: 1,GLU,270
referenced by entity poly seq: 1,GLU,274
referenced by entity poly seq: 1,GLU,292
referenced by entity poly seq: 1,GLU,311
referenced by entity poly seq: 1,GLU,312
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/4
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/11
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/12

GLY
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: GLY
chem comp.formula: C2 H5 N O2
chem comp.formula weight: 75.067
chem comp.mon nstd flag: y
chem comp.name: GLYCINE
chem comp.type: peptide linking
link to chem comp: GLY
referenced by chem comp atom: HXT,GLY
referenced by chem comp bond: OXT,HXT,GLY
referenced by entity poly seq: 1,GLY,329
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/29
referenced by chem comp atom: N,GLY
referenced by chem comp atom: CA,GLY
referenced by chem comp atom: C,GLY
referenced by chem comp atom: O,GLY
referenced by chem comp atom: OXT,GLY
referenced by chem comp atom: H,GLY
referenced by chem comp atom: H2,GLY
referenced by chem comp atom: HA2,GLY
referenced by chem comp atom: HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: C,O,GLY
referenced by chem comp bond: C,OXT,GLY
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,GLY,3
referenced by entity poly seq: 1,GLY,26
referenced by entity poly seq: 1,GLY,28
referenced by entity poly seq: 1,GLY,31
referenced by entity poly seq: 1,GLY,36
referenced by entity poly seq: 1,GLY,42
referenced by entity poly seq: 1,GLY,86
referenced by entity poly seq: 1,GLY,103
referenced by entity poly seq: 1,GLY,117
referenced by entity poly seq: 1,GLY,131
referenced by entity poly seq: 1,GLY,164
referenced by entity poly seq: 1,GLY,170
referenced by entity poly seq: 1,GLY,180
referenced by entity poly seq: 1,GLY,181
referenced by entity poly seq: 1,GLY,208
referenced by entity poly seq: 1,GLY,218
referenced by entity poly seq: 1,GLY,224
referenced by entity poly seq: 1,GLY,237
referenced by entity poly seq: 1,GLY,290
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/1
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/3

GOL
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: GOL
chem comp.formula: C3 H8 O3
chem comp.formula weight: 92.094
chem comp.name: GLYCEROL
chem comp.pdbx synonyms: GLYCERIN; PROPANE-1,2,3-TRIOL
chem comp.type: non-polymer
link to chem comp: GOL
referenced by chem comp atom: HO3,GOL
referenced by chem comp bond: O3,HO3,GOL
referenced by chem comp atom: C1,GOL
referenced by chem comp atom: O1,GOL
referenced by chem comp atom: C2,GOL
referenced by chem comp atom: O2,GOL
referenced by chem comp atom: C3,GOL
referenced by chem comp atom: O3,GOL
referenced by chem comp atom: H11,GOL
referenced by chem comp atom: H12,GOL
referenced by chem comp atom: HO1,GOL
referenced by chem comp atom: H2,GOL
referenced by chem comp atom: HO2,GOL
referenced by chem comp atom: H31,GOL
referenced by chem comp atom: H32,GOL
referenced by chem comp bond: C1,O1,GOL
referenced by chem comp bond: C1,C2,GOL
referenced by chem comp bond: C1,H11,GOL
referenced by chem comp bond: C1,H12,GOL
referenced by chem comp bond: O1,HO1,GOL
referenced by chem comp bond: C2,O2,GOL
referenced by chem comp bond: C2,C3,GOL
referenced by chem comp bond: C2,H2,GOL
referenced by chem comp bond: O2,HO2,GOL
referenced by chem comp bond: C3,O3,GOL
referenced by chem comp bond: C3,H31,GOL
referenced by chem comp bond: C3,H32,GOL

HIS
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: HIS
chem comp.formula: C6 H10 N3 O2 1
chem comp.formula weight: 156.162
chem comp.mon nstd flag: y
chem comp.name: HISTIDINE
chem comp.type: L-peptide linking
link to chem comp: HIS
referenced by chem comp atom: HXT,HIS
referenced by chem comp bond: OXT,HXT,HIS
referenced by entity poly seq: 1,HIS,295
referenced by chem comp atom: N,HIS
referenced by chem comp atom: CA,HIS
referenced by chem comp atom: C,HIS
referenced by chem comp atom: O,HIS
referenced by chem comp atom: CB,HIS
referenced by chem comp atom: CG,HIS
referenced by chem comp atom: ND1,HIS
referenced by chem comp atom: CD2,HIS
referenced by chem comp atom: CE1,HIS
referenced by chem comp atom: NE2,HIS
referenced by chem comp atom: OXT,HIS
referenced by chem comp atom: H,HIS
referenced by chem comp atom: H2,HIS
referenced by chem comp atom: HA,HIS
referenced by chem comp atom: HB2,HIS
referenced by chem comp atom: HB3,HIS
referenced by chem comp atom: HD1,HIS
referenced by chem comp atom: HD2,HIS
referenced by chem comp atom: HE1,HIS
referenced by chem comp atom: HE2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: C,O,HIS
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CD2,NE2,HIS
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: NE2,HE2,HIS
referenced by entity poly seq: 1,HIS,80
referenced by entity poly seq: 1,HIS,112
referenced by entity poly seq: 1,HIS,142
referenced by entity poly seq: 1,HIS,157
referenced by entity poly seq: 1,HIS,177
referenced by entity poly seq: 1,HIS,195
referenced by entity poly seq: 1,HIS,200

HOH
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: HOH
chem comp.formula: H2 O
chem comp.formula weight: 18.015
chem comp.name: WATER
chem comp.type: non-polymer
link to chem comp: HOH
referenced by chem comp atom: H2,HOH
referenced by chem comp bond: O,H2,HOH
referenced by chem comp atom: O,HOH
referenced by chem comp atom: H1,HOH
referenced by chem comp bond: O,H1,HOH

ILE
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: ILE
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: ISOLEUCINE
chem comp.type: L-peptide linking
link to chem comp: ILE
referenced by chem comp atom: HXT,ILE
referenced by chem comp bond: OXT,HXT,ILE
referenced by entity poly seq: 1,ILE,325
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/25
referenced by chem comp atom: N,ILE
referenced by chem comp atom: CA,ILE
referenced by chem comp atom: C,ILE
referenced by chem comp atom: O,ILE
referenced by chem comp atom: CB,ILE
referenced by chem comp atom: CG1,ILE
referenced by chem comp atom: CG2,ILE
referenced by chem comp atom: CD1,ILE
referenced by chem comp atom: OXT,ILE
referenced by chem comp atom: H,ILE
referenced by chem comp atom: H2,ILE
referenced by chem comp atom: HA,ILE
referenced by chem comp atom: HB,ILE
referenced by chem comp atom: HG12,ILE
referenced by chem comp atom: HG13,ILE
referenced by chem comp atom: HG21,ILE
referenced by chem comp atom: HG22,ILE
referenced by chem comp atom: HG23,ILE
referenced by chem comp atom: HD11,ILE
referenced by chem comp atom: HD12,ILE
referenced by chem comp atom: HD13,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: C,O,ILE
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE
referenced by chem comp bond: CD1,HD13,ILE
referenced by entity poly seq: 1,ILE,13
referenced by entity poly seq: 1,ILE,22
referenced by entity poly seq: 1,ILE,39
referenced by entity poly seq: 1,ILE,47
referenced by entity poly seq: 1,ILE,51
referenced by entity poly seq: 1,ILE,66
referenced by entity poly seq: 1,ILE,87
referenced by entity poly seq: 1,ILE,96
referenced by entity poly seq: 1,ILE,116
referenced by entity poly seq: 1,ILE,128
referenced by entity poly seq: 1,ILE,160
referenced by entity poly seq: 1,ILE,185
referenced by entity poly seq: 1,ILE,193
referenced by entity poly seq: 1,ILE,197
referenced by entity poly seq: 1,ILE,225
referenced by entity poly seq: 1,ILE,230
referenced by entity poly seq: 1,ILE,233
referenced by entity poly seq: 1,ILE,245
referenced by entity poly seq: 1,ILE,248
referenced by entity poly seq: 1,ILE,253
referenced by entity poly seq: 1,ILE,260
referenced by entity poly seq: 1,ILE,272
referenced by entity poly seq: 1,ILE,273
referenced by entity poly seq: 1,ILE,288

LEU
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: LEU
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: LEUCINE
chem comp.type: L-peptide linking
link to chem comp: LEU
referenced by chem comp atom: HXT,LEU
referenced by chem comp bond: OXT,HXT,LEU
referenced by entity poly seq: 1,LEU,324
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/24
referenced by chem comp atom: N,LEU
referenced by chem comp atom: CA,LEU
referenced by chem comp atom: C,LEU
referenced by chem comp atom: O,LEU
referenced by chem comp atom: CB,LEU
referenced by chem comp atom: CG,LEU
referenced by chem comp atom: CD1,LEU
referenced by chem comp atom: CD2,LEU
referenced by chem comp atom: OXT,LEU
referenced by chem comp atom: H,LEU
referenced by chem comp atom: H2,LEU
referenced by chem comp atom: HA,LEU
referenced by chem comp atom: HB2,LEU
referenced by chem comp atom: HB3,LEU
referenced by chem comp atom: HG,LEU
referenced by chem comp atom: HD11,LEU
referenced by chem comp atom: HD12,LEU
referenced by chem comp atom: HD13,LEU
referenced by chem comp atom: HD21,LEU
referenced by chem comp atom: HD22,LEU
referenced by chem comp atom: HD23,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: C,O,LEU
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU
referenced by chem comp bond: CD2,HD23,LEU
referenced by entity poly seq: 1,LEU,10
referenced by entity poly seq: 1,LEU,11
referenced by entity poly seq: 1,LEU,14
referenced by entity poly seq: 1,LEU,25
referenced by entity poly seq: 1,LEU,37
referenced by entity poly seq: 1,LEU,54
referenced by entity poly seq: 1,LEU,67
referenced by entity poly seq: 1,LEU,84
referenced by entity poly seq: 1,LEU,85
referenced by entity poly seq: 1,LEU,89
referenced by entity poly seq: 1,LEU,95
referenced by entity poly seq: 1,LEU,99
referenced by entity poly seq: 1,LEU,105
referenced by entity poly seq: 1,LEU,106
referenced by entity poly seq: 1,LEU,121
referenced by entity poly seq: 1,LEU,122
referenced by entity poly seq: 1,LEU,135
referenced by entity poly seq: 1,LEU,140
referenced by entity poly seq: 1,LEU,145
referenced by entity poly seq: 1,LEU,151
referenced by entity poly seq: 1,LEU,168
referenced by entity poly seq: 1,LEU,169
referenced by entity poly seq: 1,LEU,190
referenced by entity poly seq: 1,LEU,194
referenced by entity poly seq: 1,LEU,214
referenced by entity poly seq: 1,LEU,234

LYS
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: LYS
chem comp.formula: C6 H15 N2 O2 1
chem comp.formula weight: 147.195
chem comp.mon nstd flag: y
chem comp.name: LYSINE
chem comp.type: L-peptide linking
link to chem comp: LYS
referenced by chem comp atom: HXT,LYS
referenced by chem comp bond: OXT,HXT,LYS
referenced by entity poly seq: 1,LYS,277
referenced by chem comp atom: N,LYS
referenced by chem comp atom: CA,LYS
referenced by chem comp atom: C,LYS
referenced by chem comp atom: O,LYS
referenced by chem comp atom: CB,LYS
referenced by chem comp atom: CG,LYS
referenced by chem comp atom: CD,LYS
referenced by chem comp atom: CE,LYS
referenced by chem comp atom: NZ,LYS
referenced by chem comp atom: OXT,LYS
referenced by chem comp atom: H,LYS
referenced by chem comp atom: H2,LYS
referenced by chem comp atom: HA,LYS
referenced by chem comp atom: HB2,LYS
referenced by chem comp atom: HB3,LYS
referenced by chem comp atom: HG2,LYS
referenced by chem comp atom: HG3,LYS
referenced by chem comp atom: HD2,LYS
referenced by chem comp atom: HD3,LYS
referenced by chem comp atom: HE2,LYS
referenced by chem comp atom: HE3,LYS
referenced by chem comp atom: HZ1,LYS
referenced by chem comp atom: HZ2,LYS
referenced by chem comp atom: HZ3,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: C,O,LYS
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS
referenced by chem comp bond: NZ,HZ3,LYS
referenced by entity poly seq: 1,LYS,15
referenced by entity poly seq: 1,LYS,20
referenced by entity poly seq: 1,LYS,21
referenced by entity poly seq: 1,LYS,23
referenced by entity poly seq: 1,LYS,35
referenced by entity poly seq: 1,LYS,44
referenced by entity poly seq: 1,LYS,46
referenced by entity poly seq: 1,LYS,52
referenced by entity poly seq: 1,LYS,61
referenced by entity poly seq: 1,LYS,64
referenced by entity poly seq: 1,LYS,113
referenced by entity poly seq: 1,LYS,130
referenced by entity poly seq: 1,LYS,153
referenced by entity poly seq: 1,LYS,159
referenced by entity poly seq: 1,LYS,167
referenced by entity poly seq: 1,LYS,174
referenced by entity poly seq: 1,LYS,182
referenced by entity poly seq: 1,LYS,186
referenced by entity poly seq: 1,LYS,220
referenced by entity poly seq: 1,LYS,236
referenced by entity poly seq: 1,LYS,256

MET
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: MET
chem comp.formula: C5 H11 N O2 S
chem comp.formula weight: 149.211
chem comp.mon nstd flag: y
chem comp.name: METHIONINE
chem comp.type: L-peptide linking
link to chem comp: MET
referenced by chem comp atom: HXT,MET
referenced by chem comp bond: OXT,HXT,MET
referenced by entity poly seq: 1,MET,314
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/14
referenced by chem comp atom: N,MET
referenced by chem comp atom: CA,MET
referenced by chem comp atom: C,MET
referenced by chem comp atom: O,MET
referenced by chem comp atom: CB,MET
referenced by chem comp atom: CG,MET
referenced by chem comp atom: SD,MET
referenced by chem comp atom: CE,MET
referenced by chem comp atom: OXT,MET
referenced by chem comp atom: H,MET
referenced by chem comp atom: H2,MET
referenced by chem comp atom: HA,MET
referenced by chem comp atom: HB2,MET
referenced by chem comp atom: HB3,MET
referenced by chem comp atom: HG2,MET
referenced by chem comp atom: HG3,MET
referenced by chem comp atom: HE1,MET
referenced by chem comp atom: HE2,MET
referenced by chem comp atom: HE3,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: C,O,MET
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET
referenced by chem comp bond: CE,HE3,MET
referenced by entity poly seq: 1,MET,73
referenced by entity poly seq: 1,MET,97
referenced by entity poly seq: 1,MET,100
referenced by entity poly seq: 1,MET,132
referenced by entity poly seq: 1,MET,188
referenced by entity poly seq: 1,MET,215
referenced by entity poly seq: 1,MET,252
referenced by entity poly seq: 1,MET,254
referenced by entity poly seq: 1,MET,259
referenced by entity poly seq: 1,MET,278
referenced by entity poly seq: 1,MET,294
referenced by entity poly seq: 1,MET,309
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/9

PHE
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: PHE
chem comp.formula: C9 H11 N O2
chem comp.formula weight: 165.189
chem comp.mon nstd flag: y
chem comp.name: PHENYLALANINE
chem comp.type: L-peptide linking
link to chem comp: PHE
referenced by chem comp atom: HXT,PHE
referenced by chem comp bond: OXT,HXT,PHE
referenced by entity poly seq: 1,PHE,304
referenced by chem comp atom: N,PHE
referenced by chem comp atom: CA,PHE
referenced by chem comp atom: C,PHE
referenced by chem comp atom: O,PHE
referenced by chem comp atom: CB,PHE
referenced by chem comp atom: CG,PHE
referenced by chem comp atom: CD1,PHE
referenced by chem comp atom: CD2,PHE
referenced by chem comp atom: CE1,PHE
referenced by chem comp atom: CE2,PHE
referenced by chem comp atom: CZ,PHE
referenced by chem comp atom: OXT,PHE
referenced by chem comp atom: H,PHE
referenced by chem comp atom: H2,PHE
referenced by chem comp atom: HA,PHE
referenced by chem comp atom: HB2,PHE
referenced by chem comp atom: HB3,PHE
referenced by chem comp atom: HD1,PHE
referenced by chem comp atom: HD2,PHE
referenced by chem comp atom: HE1,PHE
referenced by chem comp atom: HE2,PHE
referenced by chem comp atom: HZ,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: C,O,PHE
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CE1,CZ,PHE
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CZ,HZ,PHE
referenced by entity poly seq: 1,PHE,19
referenced by entity poly seq: 1,PHE,30
referenced by entity poly seq: 1,PHE,102
referenced by entity poly seq: 1,PHE,163
referenced by entity poly seq: 1,PHE,217
referenced by entity poly seq: 1,PHE,268
referenced by entity poly seq: 1,PHE,275

PRO
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: PRO
chem comp.formula: C5 H9 N O2
chem comp.formula weight: 115.13
chem comp.mon nstd flag: y
chem comp.name: PROLINE
chem comp.type: L-peptide linking
link to chem comp: PRO
referenced by chem comp atom: HXT,PRO
referenced by chem comp bond: OXT,HXT,PRO
referenced by entity poly seq: 1,PRO,326
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/26
referenced by chem comp atom: N,PRO
referenced by chem comp atom: CA,PRO
referenced by chem comp atom: C,PRO
referenced by chem comp atom: O,PRO
referenced by chem comp atom: CB,PRO
referenced by chem comp atom: CG,PRO
referenced by chem comp atom: CD,PRO
referenced by chem comp atom: OXT,PRO
referenced by chem comp atom: H,PRO
referenced by chem comp atom: HA,PRO
referenced by chem comp atom: HB2,PRO
referenced by chem comp atom: HB3,PRO
referenced by chem comp atom: HG2,PRO
referenced by chem comp atom: HG3,PRO
referenced by chem comp atom: HD2,PRO
referenced by chem comp atom: HD3,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: C,O,PRO
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CD,HD2,PRO
referenced by chem comp bond: CD,HD3,PRO
referenced by entity poly seq: 1,PRO,6
referenced by entity poly seq: 1,PRO,40
referenced by entity poly seq: 1,PRO,48
referenced by entity poly seq: 1,PRO,60
referenced by entity poly seq: 1,PRO,79
referenced by entity poly seq: 1,PRO,101
referenced by entity poly seq: 1,PRO,155
referenced by entity poly seq: 1,PRO,184
referenced by entity poly seq: 1,PRO,221
referenced by entity poly seq: 1,PRO,226
referenced by entity poly seq: 1,PRO,241
referenced by entity poly seq: 1,PRO,243
referenced by entity poly seq: 1,PRO,244
referenced by entity poly seq: 1,PRO,266
referenced by entity poly seq: 1,PRO,282
referenced by entity poly seq: 1,PRO,297
referenced by entity poly seq: 1,PRO,299
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/6

SER
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: SER
chem comp.formula: C3 H7 N O3
chem comp.formula weight: 105.093
chem comp.mon nstd flag: y
chem comp.name: SERINE
chem comp.type: L-peptide linking
link to chem comp: SER
referenced by chem comp atom: HXT,SER
referenced by chem comp bond: OXT,HXT,SER
referenced by entity poly seq: 1,SER,302
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/2
referenced by chem comp atom: N,SER
referenced by chem comp atom: CA,SER
referenced by chem comp atom: C,SER
referenced by chem comp atom: O,SER
referenced by chem comp atom: CB,SER
referenced by chem comp atom: OG,SER
referenced by chem comp atom: OXT,SER
referenced by chem comp atom: H,SER
referenced by chem comp atom: H2,SER
referenced by chem comp atom: HA,SER
referenced by chem comp atom: HB2,SER
referenced by chem comp atom: HB3,SER
referenced by chem comp atom: HG,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: C,O,SER
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: OG,HG,SER
referenced by entity poly seq: 1,SER,2
referenced by entity poly seq: 1,SER,27
referenced by entity poly seq: 1,SER,59
referenced by entity poly seq: 1,SER,75
referenced by entity poly seq: 1,SER,91
referenced by entity poly seq: 1,SER,118
referenced by entity poly seq: 1,SER,192
referenced by entity poly seq: 1,SER,202
referenced by entity poly seq: 1,SER,206
referenced by entity poly seq: 1,SER,219
referenced by entity poly seq: 1,SER,228
referenced by entity poly seq: 1,SER,231
referenced by entity poly seq: 1,SER,232
referenced by entity poly seq: 1,SER,264
referenced by entity poly seq: 1,SER,276
referenced by entity poly seq: 1,SER,298

SO4
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: SO4
chem comp.formula: O4 S -2
chem comp.formula weight: 96.063
chem comp.name: SULFATE ION
chem comp.type: non-polymer
link to chem comp: SO4
referenced by chem comp atom: O4,SO4
referenced by chem comp bond: S,O4,SO4
referenced by chem comp atom: S,SO4
referenced by chem comp atom: O1,SO4
referenced by chem comp atom: O2,SO4
referenced by chem comp atom: O3,SO4
referenced by chem comp bond: S,O1,SO4
referenced by chem comp bond: S,O2,SO4
referenced by chem comp bond: S,O3,SO4

THR
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: THR
chem comp.formula: C4 H9 N O3
chem comp.formula weight: 119.119
chem comp.mon nstd flag: y
chem comp.name: THREONINE
chem comp.type: L-peptide linking
link to chem comp: THR
referenced by chem comp atom: HXT,THR
referenced by chem comp bond: OXT,HXT,THR
referenced by entity poly seq: 1,THR,300
referenced by chem comp atom: N,THR
referenced by chem comp atom: CA,THR
referenced by chem comp atom: C,THR
referenced by chem comp atom: O,THR
referenced by chem comp atom: CB,THR
referenced by chem comp atom: OG1,THR
referenced by chem comp atom: CG2,THR
referenced by chem comp atom: OXT,THR
referenced by chem comp atom: H,THR
referenced by chem comp atom: H2,THR
referenced by chem comp atom: HA,THR
referenced by chem comp atom: HB,THR
referenced by chem comp atom: HG1,THR
referenced by chem comp atom: HG21,THR
referenced by chem comp atom: HG22,THR
referenced by chem comp atom: HG23,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: C,O,THR
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR
referenced by chem comp bond: CG2,HG23,THR
referenced by entity poly seq: 1,THR,17
referenced by entity poly seq: 1,THR,32
referenced by entity poly seq: 1,THR,58
referenced by entity poly seq: 1,THR,90
referenced by entity poly seq: 1,THR,92
referenced by entity poly seq: 1,THR,154
referenced by entity poly seq: 1,THR,161
referenced by entity poly seq: 1,THR,199
referenced by entity poly seq: 1,THR,210
referenced by entity poly seq: 1,THR,216
referenced by entity poly seq: 1,THR,247

TRP
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: TRP
chem comp.formula: C11 H12 N2 O2
chem comp.formula weight: 204.225
chem comp.mon nstd flag: y
chem comp.name: TRYPTOPHAN
chem comp.type: L-peptide linking
link to chem comp: TRP
referenced by chem comp atom: HXT,TRP
referenced by chem comp bond: OXT,HXT,TRP
referenced by entity poly seq: 1,TRP,258
referenced by chem comp atom: N,TRP
referenced by chem comp atom: CA,TRP
referenced by chem comp atom: C,TRP
referenced by chem comp atom: O,TRP
referenced by chem comp atom: CB,TRP
referenced by chem comp atom: CG,TRP
referenced by chem comp atom: CD1,TRP
referenced by chem comp atom: CD2,TRP
referenced by chem comp atom: NE1,TRP
referenced by chem comp atom: CE2,TRP
referenced by chem comp atom: CE3,TRP
referenced by chem comp atom: CZ2,TRP
referenced by chem comp atom: CZ3,TRP
referenced by chem comp atom: CH2,TRP
referenced by chem comp atom: OXT,TRP
referenced by chem comp atom: H,TRP
referenced by chem comp atom: H2,TRP
referenced by chem comp atom: HA,TRP
referenced by chem comp atom: HB2,TRP
referenced by chem comp atom: HB3,TRP
referenced by chem comp atom: HD1,TRP
referenced by chem comp atom: HE1,TRP
referenced by chem comp atom: HE3,TRP
referenced by chem comp atom: HZ2,TRP
referenced by chem comp atom: HZ3,TRP
referenced by chem comp atom: HH2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: C,O,TRP
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CD2,CE2,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CZ2,CH2,TRP
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CH2,HH2,TRP
referenced by entity poly seq: 1,TRP,38
referenced by entity poly seq: 1,TRP,124
referenced by entity poly seq: 1,TRP,187
referenced by entity poly seq: 1,TRP,205
referenced by entity poly seq: 1,TRP,212

TYR
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: TYR
chem comp.formula: C9 H11 N O3
chem comp.formula weight: 181.189
chem comp.mon nstd flag: y
chem comp.name: TYROSINE
chem comp.type: L-peptide linking
link to chem comp: TYR
referenced by chem comp atom: HXT,TYR
referenced by chem comp bond: OXT,HXT,TYR
referenced by entity poly seq: 1,TYR,323
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/23
referenced by chem comp atom: N,TYR
referenced by chem comp atom: CA,TYR
referenced by chem comp atom: C,TYR
referenced by chem comp atom: O,TYR
referenced by chem comp atom: CB,TYR
referenced by chem comp atom: CG,TYR
referenced by chem comp atom: CD1,TYR
referenced by chem comp atom: CD2,TYR
referenced by chem comp atom: CE1,TYR
referenced by chem comp atom: CE2,TYR
referenced by chem comp atom: CZ,TYR
referenced by chem comp atom: OH,TYR
referenced by chem comp atom: OXT,TYR
referenced by chem comp atom: H,TYR
referenced by chem comp atom: H2,TYR
referenced by chem comp atom: HA,TYR
referenced by chem comp atom: HB2,TYR
referenced by chem comp atom: HB3,TYR
referenced by chem comp atom: HD1,TYR
referenced by chem comp atom: HD2,TYR
referenced by chem comp atom: HE1,TYR
referenced by chem comp atom: HE2,TYR
referenced by chem comp atom: HH,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: C,O,TYR
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CE1,CZ,TYR
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: OH,HH,TYR
referenced by entity poly seq: 1,TYR,34
referenced by entity poly seq: 1,TYR,71
referenced by entity poly seq: 1,TYR,108
referenced by entity poly seq: 1,TYR,120
referenced by entity poly seq: 1,TYR,134
referenced by entity poly seq: 1,TYR,176
referenced by entity poly seq: 1,TYR,198
referenced by entity poly seq: 1,TYR,207
referenced by entity poly seq: 1,TYR,222
referenced by entity poly seq: 1,TYR,251
referenced by entity poly seq: 1,TYR,285
referenced by entity poly seq: 1,TYR,305

VAL
type: chem comp
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
chem comp.id: VAL
chem comp.formula: C5 H11 N O2
chem comp.formula weight: 117.146
chem comp.mon nstd flag: y
chem comp.name: VALINE
chem comp.type: L-peptide linking
link to chem comp: VAL
referenced by chem comp atom: HXT,VAL
referenced by chem comp bond: OXT,HXT,VAL
referenced by entity poly seq: 1,VAL,318
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/18
referenced by chem comp atom: N,VAL
referenced by chem comp atom: CA,VAL
referenced by chem comp atom: C,VAL
referenced by chem comp atom: O,VAL
referenced by chem comp atom: CB,VAL
referenced by chem comp atom: CG1,VAL
referenced by chem comp atom: CG2,VAL
referenced by chem comp atom: OXT,VAL
referenced by chem comp atom: H,VAL
referenced by chem comp atom: H2,VAL
referenced by chem comp atom: HA,VAL
referenced by chem comp atom: HB,VAL
referenced by chem comp atom: HG11,VAL
referenced by chem comp atom: HG12,VAL
referenced by chem comp atom: HG13,VAL
referenced by chem comp atom: HG21,VAL
referenced by chem comp atom: HG22,VAL
referenced by chem comp atom: HG23,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: C,O,VAL
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL
referenced by chem comp bond: CG2,HG23,VAL
referenced by entity poly seq: 1,VAL,24
referenced by entity poly seq: 1,VAL,33
referenced by entity poly seq: 1,VAL,45
referenced by entity poly seq: 1,VAL,49
referenced by entity poly seq: 1,VAL,72
referenced by entity poly seq: 1,VAL,76
referenced by entity poly seq: 1,VAL,81
referenced by entity poly seq: 1,VAL,93
referenced by entity poly seq: 1,VAL,109
referenced by entity poly seq: 1,VAL,126
referenced by entity poly seq: 1,VAL,141
referenced by entity poly seq: 1,VAL,150
referenced by entity poly seq: 1,VAL,152
referenced by entity poly seq: 1,VAL,158
referenced by entity poly seq: 1,VAL,183
referenced by entity poly seq: 1,VAL,204
referenced by entity poly seq: 1,VAL,209
referenced by entity poly seq: 1,VAL,211
referenced by entity poly seq: 1,VAL,250
referenced by entity poly seq: 1,VAL,287
referenced by entity poly seq: 1,VAL,317
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/17

C4,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C4
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 1
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C4,C3,634
referenced by chem comp bond: C9,C4,634
referenced by chem comp bond: C5,C4,634

C5,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C5
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 2
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C5,C4,634
referenced by chem comp bond: N7,C5,634
referenced by chem comp bond: C5,N6,634

C8,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C8
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 3
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C8,H1,634
referenced by chem comp bond: N7,C8,634
referenced by chem comp bond: C8,C9,634

C13,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C13
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 4
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C13,H2,634
referenced by chem comp bond: C12,C13,634
referenced by chem comp bond: C13,C14,634

C15,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C15
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 5
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C15,N17,634
referenced by chem comp bond: C16,C15,634
referenced by chem comp bond: C14,C15,634

C20,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C20
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 6
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C20,H4,634
referenced by chem comp bond: C18,C20,634
referenced by chem comp bond: C20,C21,634
referenced by chem comp bond: C20,H3,634

C21,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C21
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 7
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C21,H7,634
referenced by chem comp bond: C20,C21,634
referenced by chem comp bond: C21,H5,634
referenced by chem comp bond: C21,H6,634

C24,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C24
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 8
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C24,H8,634
referenced by chem comp bond: C23,C24,634
referenced by chem comp bond: C24,N25,634

C28,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C28
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 9
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C28,H11,634
referenced by chem comp bond: N25,C28,634
referenced by chem comp bond: C28,H9,634
referenced by chem comp bond: C28,H10,634

C1,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C1
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 10
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C1,N2,634
referenced by chem comp bond: N6,C1,634
referenced by chem comp bond: C1,N22,634

N2,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N2
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 11
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: C3,N2,634
referenced by chem comp bond: C1,N2,634

C3,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C3
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 12
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C3,O10,634
referenced by chem comp bond: C4,C3,634
referenced by chem comp bond: C3,N2,634

N6,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N6
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 13
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N6,C1,634
referenced by chem comp bond: C5,N6,634

N7,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N7
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 14
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N7,H12,634
referenced by chem comp bond: N7,C8,634
referenced by chem comp bond: N7,C5,634

C9,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C9
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 15
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C9,H13,634
referenced by chem comp bond: C8,C9,634
referenced by chem comp bond: C9,C4,634

O10,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: O10
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 16
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O10,C11,634
referenced by chem comp bond: C3,O10,634

C11,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C11
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 17
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C11,C16,634
referenced by chem comp bond: O10,C11,634
referenced by chem comp bond: C12,C11,634

C12,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C12
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 18
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C12,H14,634
referenced by chem comp bond: C12,C13,634
referenced by chem comp bond: C12,C11,634

C14,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C14
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 19
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C14,H15,634
referenced by chem comp bond: C13,C14,634
referenced by chem comp bond: C14,C15,634

C16,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C16
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 20
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C16,H16,634
referenced by chem comp bond: C11,C16,634
referenced by chem comp bond: C16,C15,634

N17,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N17
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 21
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N17,H17,634
referenced by chem comp bond: C15,N17,634
referenced by chem comp bond: N17,C18,634

C18,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C18
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 22
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C18,C20,634
referenced by chem comp bond: O19,C18,634
referenced by chem comp bond: N17,C18,634

O19,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: O19
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 23
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O19,C18,634

N22,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N22
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 24
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N22,H18,634
referenced by chem comp bond: C1,N22,634
referenced by chem comp bond: N22,C23,634

C23,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C23
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 25
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C23,C24,634
referenced by chem comp bond: N22,C23,634
referenced by chem comp bond: C23,C27,634

N25,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N25
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 26
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N25,C28,634
referenced by chem comp bond: N26,N25,634
referenced by chem comp bond: C24,N25,634

N26,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: N26
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 27
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N26,N25,634
referenced by chem comp bond: C27,N26,634

C27,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: C27
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 28
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C27,H19,634
referenced by chem comp bond: C23,C27,634
referenced by chem comp bond: C27,N26,634

H1,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H1
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 29
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C8,H1,634

H2,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H2
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 30
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C13,H2,634

H3,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H3
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 31
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C20,H3,634

H4,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H4
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 32
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C20,H4,634

H5,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H5
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 33
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C21,H5,634

H6,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H6
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 34
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C21,H6,634

H7,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H7
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 35
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C21,H7,634

H8,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H8
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 36
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C24,H8,634

H9,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H9
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 37
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C28,H9,634

H10,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H10
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 38
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C28,H10,634

H11,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H11
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 39
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C28,H11,634

H12,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H12
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 40
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N7,H12,634

H13,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H13
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 41
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C9,H13,634

H14,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H14
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 42
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C12,H14,634

H15,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H15
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 43
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C14,H15,634

H16,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H16
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 44
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C16,H16,634

H17,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H17
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 45
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N17,H17,634

H18,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H18
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 46
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N22,H18,634

H19,634
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp atom.atom id: H19
chem comp atom.comp id: 634
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 47
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C27,H19,634

N,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: N
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 48
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA

CA,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: CA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 49
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA

C,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: C
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 50
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: C,O,ALA

O,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: O
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 51
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ALA

CB,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: CB
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 52
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA

OXT,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: OXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 53
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ALA
referenced by chem comp bond: C,OXT,ALA

H,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: H
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 54
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ALA

H2,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: H2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 55
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ALA

HA,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: HA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 56
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ALA

HB1,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: HB1
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 57
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB1,ALA

HB2,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: HB2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 58
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ALA

HB3,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: HB3
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 59
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ALA

HXT,ALA
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
chem comp atom.atom id: HXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 60
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ALA

N,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: N
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 61
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG

CA,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: CA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 62
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG

C,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: C
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 63
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: C,O,ARG

O,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: O
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 64
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ARG

CB,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: CB
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 65
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG

CG,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: CG
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 66
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG

CD,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: CD
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 67
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG

NE,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: NE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 68
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: NE,CZ,ARG

CZ,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: CZ
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 69
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: CZ,NH1,ARG

NH1,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: NH1
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 70
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: NH1,HH11,ARG

NH2,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: NH2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 71
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH2,HH22,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH2,HH21,ARG

OXT,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: OXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 72
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ARG
referenced by chem comp bond: C,OXT,ARG

H,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: H
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 73
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ARG

H2,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: H2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 74
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ARG

HA,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 75
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ARG

HB2,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HB2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 76
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ARG

HB3,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HB3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 77
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ARG

HG2,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HG2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 78
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,ARG

HG3,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HG3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 79
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,ARG

HD2,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HD2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 80
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,ARG

HD3,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HD3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 81
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,ARG

HE,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 82
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE,HE,ARG

HH11,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HH11
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 83
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH11,ARG

HH12,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HH12
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 84
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH12,ARG

HH21,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HH21
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 85
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH21,ARG

HH22,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HH22
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 86
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH22,ARG

HXT,ARG
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
chem comp atom.atom id: HXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 87
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ARG

N,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: N
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 88
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN

CA,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: CA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 89
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN

C,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: C
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 90
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: C,O,ASN

O,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: O
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 91
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASN

CB,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: CB
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 92
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN

CG,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: CG
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 93
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CG,OD1,ASN

OD1,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: OD1
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 94
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASN

ND2,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: ND2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 95
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND2,HD22,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN

OXT,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: OXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 96
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASN
referenced by chem comp bond: C,OXT,ASN

H,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: H
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 97
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASN

H2,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: H2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 98
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASN

HA,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 99
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASN

HB2,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HB2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 100
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASN

HB3,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HB3
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 101
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASN

HD21,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HD21
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 102
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD21,ASN

HD22,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HD22
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 103
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD22,ASN

HXT,ASN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
chem comp atom.atom id: HXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 104
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASN

N,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: N
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 105
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP

CA,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: CA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 106
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP

C,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: C
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 107
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: C,O,ASP

O,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: O
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 108
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASP

CB,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: CB
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 109
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP

CG,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: CG
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 110
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CG,OD1,ASP

OD1,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: OD1
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 111
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASP

OD2,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: OD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 112
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OD2,HD2,ASP
referenced by chem comp bond: CG,OD2,ASP

OXT,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: OXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 113
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASP
referenced by chem comp bond: C,OXT,ASP

H,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: H
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 114
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASP

H2,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: H2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 115
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASP

HA,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: HA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 116
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASP

HB2,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: HB2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 117
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASP

HB3,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: HB3
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 118
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASP

HD2,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: HD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 119
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OD2,HD2,ASP

HXT,ASP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
chem comp atom.atom id: HXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 120
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASP

N,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: N
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 121
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS

CA,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: CA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 122
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS

C,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: C
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 123
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: C,O,CYS

O,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: O
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 124
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,CYS

CB,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: CB
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 125
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS

SG,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: SG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 126
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SG,HG,CYS
referenced by chem comp bond: CB,SG,CYS

OXT,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: OXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 127
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,CYS
referenced by chem comp bond: C,OXT,CYS

H,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: H
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 128
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,CYS

H2,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: H2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 129
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,CYS

HA,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: HA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 130
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,CYS

HB2,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: HB2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 131
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,CYS

HB3,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: HB3
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 132
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,CYS

HG,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: HG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 133
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: SG,HG,CYS

HXT,CYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
chem comp atom.atom id: HXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 134
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,CYS

N,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: N
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 135
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN

CA,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: CA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 136
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN

C,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: C
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 137
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: C,O,GLN

O,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: O
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 138
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLN

CB,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: CB
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 139
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN

CG,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: CG
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 140
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN

CD,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: CD
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 141
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CD,OE1,GLN

OE1,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: OE1
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 142
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLN

NE2,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: NE2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 143
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE22,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN

OXT,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: OXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 144
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLN
referenced by chem comp bond: C,OXT,GLN

H,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: H
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 145
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLN

H2,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: H2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 146
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLN

HA,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 147
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLN

HB2,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HB2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 148
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLN

HB3,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HB3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 149
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLN

HG2,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HG2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 150
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLN

HG3,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HG3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 151
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLN

HE21,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HE21
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 152
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE21,GLN

HE22,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HE22
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 153
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE22,GLN

HXT,GLN
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
chem comp atom.atom id: HXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 154
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLN

N,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: N
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 155
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU

CA,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: CA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 156
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU

C,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: C
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 157
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: C,O,GLU

O,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: O
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 158
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLU

CB,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: CB
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 159
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU

CG,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: CG
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 160
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU

CD,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: CD
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 161
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CD,OE1,GLU

OE1,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: OE1
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 162
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLU

OE2,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: OE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 163
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OE2,HE2,GLU
referenced by chem comp bond: CD,OE2,GLU

OXT,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: OXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 164
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLU
referenced by chem comp bond: C,OXT,GLU

H,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: H
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 165
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLU

H2,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: H2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 166
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLU

HA,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 167
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLU

HB2,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HB2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 168
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLU

HB3,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HB3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 169
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLU

HG2,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HG2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 170
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLU

HG3,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HG3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 171
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLU

HE2,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 172
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OE2,HE2,GLU

HXT,GLU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
chem comp atom.atom id: HXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 173
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLU

N,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: N
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 174
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY

CA,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: CA
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 175
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY

C,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: C
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 176
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: C,O,GLY

O,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: O
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 177
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLY

OXT,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: OXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 178
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLY
referenced by chem comp bond: C,OXT,GLY

H,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: H
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 179
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLY

H2,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: H2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 180
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLY

HA2,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: HA2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 181
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA2,GLY

HA3,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: HA3
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 182
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA3,GLY

HXT,GLY
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
chem comp atom.atom id: HXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 183
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLY

C1,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: C1
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 184
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C1,H12,GOL
referenced by chem comp bond: C1,O1,GOL
referenced by chem comp bond: C1,C2,GOL
referenced by chem comp bond: C1,H11,GOL

O1,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: O1
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 185
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O1,HO1,GOL
referenced by chem comp bond: C1,O1,GOL

C2,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: C2
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 186
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C2,H2,GOL
referenced by chem comp bond: C1,C2,GOL
referenced by chem comp bond: C2,O2,GOL
referenced by chem comp bond: C2,C3,GOL

O2,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: O2
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 187
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O2,HO2,GOL
referenced by chem comp bond: C2,O2,GOL

C3,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: C3
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 188
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C3,H32,GOL
referenced by chem comp bond: C2,C3,GOL
referenced by chem comp bond: C3,O3,GOL
referenced by chem comp bond: C3,H31,GOL

O3,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: O3
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 189
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O3,HO3,GOL
referenced by chem comp bond: C3,O3,GOL

H11,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: H11
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 190
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H11,GOL

H12,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: H12
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 191
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H12,GOL

HO1,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: HO1
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 192
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O1,HO1,GOL

H2,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: H2
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 193
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C2,H2,GOL

HO2,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: HO2
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 194
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O2,HO2,GOL

H31,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: H31
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 195
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C3,H31,GOL

H32,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: H32
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 196
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C3,H32,GOL

HO3,GOL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GOL
chem comp atom.atom id: HO3
chem comp atom.comp id: GOL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 197
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O3,HO3,GOL

N,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: N
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 198
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS

CA,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: CA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 199
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS

C,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: C
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 200
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: C,O,HIS

O,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: O
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 201
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,HIS

CB,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: CB
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 202
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS

CG,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: CG
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 203
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CG,ND1,HIS

ND1,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: ND1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 204
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: ND1,CE1,HIS

CD2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: CD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 205
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CD2,NE2,HIS

CE1,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: CE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 206
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: CE1,NE2,HIS

NE2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: NE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 207
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CD2,NE2,HIS

OXT,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: OXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 208
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,HIS
referenced by chem comp bond: C,OXT,HIS

H,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: H
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 209
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,HIS

H2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: H2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 210
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,HIS

HA,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 211
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,HIS

HB2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HB2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 212
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,HIS

HB3,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HB3
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 213
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,HIS

HD1,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HD1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 214
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND1,HD1,HIS

HD2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 215
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,HIS

HE1,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 216
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,HIS

HE2,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 217
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE2,HIS

HXT,HIS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
chem comp atom.atom id: HXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 218
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,HIS

O,HOH
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HOH
chem comp atom.atom id: O
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 219
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O,H2,HOH
referenced by chem comp bond: O,H1,HOH

H1,HOH
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HOH
chem comp atom.atom id: H1
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 220
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H1,HOH

H2,HOH
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HOH
chem comp atom.atom id: H2
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 221
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H2,HOH

N,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: N
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 222
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE

CA,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: CA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 223
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE

C,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: C
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 224
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: C,O,ILE

O,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: O
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 225
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ILE

CB,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: CB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 226
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE

CG1,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: CG1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 227
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE

CG2,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: CG2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 228
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE

CD1,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: CD1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 229
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE

OXT,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: OXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 230
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ILE
referenced by chem comp bond: C,OXT,ILE

H,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: H
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 231
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ILE

H2,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: H2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 232
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ILE

HA,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 233
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ILE

HB,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 234
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,ILE

HG12,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HG12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 235
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,ILE

HG13,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HG13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 236
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,ILE

HG21,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HG21
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 237
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,ILE

HG22,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HG22
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 238
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,ILE

HG23,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HG23
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 239
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,ILE

HD11,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HD11
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 240
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,ILE

HD12,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HD12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 241
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,ILE

HD13,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HD13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 242
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,ILE

HXT,ILE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
chem comp atom.atom id: HXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 243
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ILE

N,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: N
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 244
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU

CA,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: CA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 245
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU

C,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: C
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 246
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: C,O,LEU

O,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: O
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 247
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LEU

CB,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: CB
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 248
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU

CG,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: CG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 249
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU

CD1,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: CD1
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 250
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU

CD2,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: CD2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 251
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD23,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU

OXT,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: OXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 252
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LEU
referenced by chem comp bond: C,OXT,LEU

H,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: H
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 253
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LEU

H2,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: H2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 254
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LEU

HA,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 255
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LEU

HB2,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HB2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 256
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LEU

HB3,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HB3
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 257
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LEU

HG,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 258
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG,LEU

HD11,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD11
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 259
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,LEU

HD12,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD12
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 260
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,LEU

HD13,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD13
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 261
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,LEU

HD21,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD21
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 262
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD21,LEU

HD22,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD22
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 263
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD22,LEU

HD23,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HD23
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 264
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD23,LEU

HXT,LEU
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
chem comp atom.atom id: HXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 265
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LEU

N,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: N
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 266
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS

CA,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: CA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 267
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS

C,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: C
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 268
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: C,O,LYS

O,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: O
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 269
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LYS

CB,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: CB
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 270
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS

CG,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: CG
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 271
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS

CD,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: CD
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 272
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS

CE,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: CE
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 273
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS

NZ,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: NZ
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 274
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NZ,HZ3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS

OXT,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: OXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 275
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LYS
referenced by chem comp bond: C,OXT,LYS

H,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: H
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 276
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LYS

H2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: H2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 277
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LYS

HA,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 278
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LYS

HB2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HB2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 279
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LYS

HB3,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HB3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 280
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LYS

HG2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HG2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 281
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,LYS

HG3,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HG3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 282
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,LYS

HD2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HD2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 283
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,LYS

HD3,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HD3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 284
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,LYS

HE2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HE2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 285
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,LYS

HE3,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HE3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 286
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,LYS

HZ1,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HZ1
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 287
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ1,LYS

HZ2,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HZ2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 288
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ2,LYS

HZ3,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HZ3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 289
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ3,LYS

HXT,LYS
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
chem comp atom.atom id: HXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 290
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LYS

N,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: N
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 291
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET

CA,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: CA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 292
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET

C,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: C
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 293
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: C,O,MET

O,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: O
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 294
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,MET

CB,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: CB
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 295
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET

CG,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: CG
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 296
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET

SD,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: SD
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 297
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CG,SD,MET

CE,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: CE
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 298
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET

OXT,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: OXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 299
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,MET
referenced by chem comp bond: C,OXT,MET

H,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: H
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 300
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,MET

H2,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: H2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 301
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,MET

HA,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 302
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,MET

HB2,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HB2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 303
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,MET

HB3,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HB3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 304
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,MET

HG2,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HG2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 305
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,MET

HG3,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HG3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 306
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,MET

HE1,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HE1
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 307
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE1,MET

HE2,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HE2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 308
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,MET

HE3,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HE3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 309
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,MET

HXT,MET
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
chem comp atom.atom id: HXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 310
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,MET

N,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: N
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 311
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE

CA,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 312
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE

C,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: C
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 313
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: C,O,PHE

O,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: O
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 314
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PHE

CB,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CB
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 315
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE

CG,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CG
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 316
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CG,CD1,PHE

CD1,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 317
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CD1,CE1,PHE

CD2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 318
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD2,CE2,PHE

CE1,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 319
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CE1,CZ,PHE

CE2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 320
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CE2,CZ,PHE

CZ,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: CZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 321
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,HZ,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE1,CZ,PHE

OXT,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: OXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 322
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PHE
referenced by chem comp bond: C,OXT,PHE

H,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: H
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 323
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PHE

H2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: H2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 324
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,PHE

HA,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 325
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PHE

HB2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HB2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 326
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PHE

HB3,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HB3
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 327
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PHE

HD1,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 328
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,PHE

HD2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 329
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,PHE

HE1,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 330
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,PHE

HE2,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 331
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,PHE

HZ,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 332
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ,HZ,PHE

HXT,PHE
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
chem comp atom.atom id: HXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 333
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PHE

N,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: N
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 334
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO

CA,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: CA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 335
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO

C,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: C
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 336
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: C,O,PRO

O,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: O
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 337
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PRO

CB,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: CB
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 338
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO

CG,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: CG
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 339
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO

CD,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: CD
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 340
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: CD,HD2,PRO

OXT,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: OXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 341
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PRO
referenced by chem comp bond: C,OXT,PRO

H,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: H
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 342
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PRO

HA,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 343
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PRO

HB2,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HB2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 344
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PRO

HB3,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HB3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 345
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PRO

HG2,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HG2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 346
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,PRO

HG3,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HG3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 347
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,PRO

HD2,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HD2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 348
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,PRO

HD3,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HD3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 349
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,PRO

HXT,PRO
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
chem comp atom.atom id: HXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 350
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PRO

N,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: N
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 351
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER

CA,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: CA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 352
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER

C,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: C
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 353
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: C,O,SER

O,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: O
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 354
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,SER

CB,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: CB
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 355
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER

OG,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: OG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 356
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG,HG,SER
referenced by chem comp bond: CB,OG,SER

OXT,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: OXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 357
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,SER
referenced by chem comp bond: C,OXT,SER

H,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: H
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 358
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,SER

H2,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: H2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 359
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,SER

HA,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: HA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 360
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,SER

HB2,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: HB2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 361
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,SER

HB3,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: HB3
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 362
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,SER

HG,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: HG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 363
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG,HG,SER

HXT,SER
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
chem comp atom.atom id: HXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 364
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,SER

S,SO4
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SO4
chem comp atom.atom id: S
chem comp atom.comp id: SO4
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 365
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: S,O4,SO4
referenced by chem comp bond: S,O1,SO4
referenced by chem comp bond: S,O2,SO4
referenced by chem comp bond: S,O3,SO4

O1,SO4
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SO4
chem comp atom.atom id: O1
chem comp atom.comp id: SO4
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 366
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: S,O1,SO4

O2,SO4
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SO4
chem comp atom.atom id: O2
chem comp atom.comp id: SO4
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 367
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: S,O2,SO4

O3,SO4
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SO4
chem comp atom.atom id: O3
chem comp atom.comp id: SO4
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 368
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: S,O3,SO4

O4,SO4
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SO4
chem comp atom.atom id: O4
chem comp atom.comp id: SO4
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 369
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: S,O4,SO4

N,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: N
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 370
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR

CA,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: CA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 371
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR

C,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: C
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 372
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: C,O,THR

O,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: O
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 373
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,THR

CB,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: CB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 374
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR

OG1,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: OG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 375
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CB,OG1,THR

CG2,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: CG2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 376
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR

OXT,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: OXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 377
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,THR
referenced by chem comp bond: C,OXT,THR

H,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: H
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 378
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,THR

H2,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: H2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 379
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,THR

HA,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 380
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,THR

HB,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 381
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,THR

HG1,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 382
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG1,HG1,THR

HG21,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HG21
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 383
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,THR

HG22,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HG22
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 384
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,THR

HG23,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HG23
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 385
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,THR

HXT,THR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
chem comp atom.atom id: HXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 386
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,THR

N,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: N
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 387
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP

CA,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 388
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP

C,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: C
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 389
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: C,O,TRP

O,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: O
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 390
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TRP

CB,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CB
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 391
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP

CG,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CG
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 392
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CG,CD1,TRP

CD1,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 393
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CD1,NE1,TRP

CD2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CD2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 394
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD2,CE2,TRP

NE1,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: NE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 395
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: NE1,CE2,TRP

CE2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CE2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 396
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: CD2,CE2,TRP

CE3,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 397
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CE3,CZ3,TRP

CZ2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 398
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

CZ3,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 399
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CZ3,CH2,TRP

CH2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: CH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 400
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CH2,HH2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

OXT,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: OXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 401
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TRP
referenced by chem comp bond: C,OXT,TRP

H,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: H
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 402
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TRP

H2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: H2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 403
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TRP

HA,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 404
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TRP

HB2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HB2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 405
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TRP

HB3,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HB3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 406
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TRP

HD1,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 407
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TRP

HE1,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 408
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE1,HE1,TRP

HE3,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 409
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE3,HE3,TRP

HZ2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 410
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ2,HZ2,TRP

HZ3,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 411
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ3,HZ3,TRP

HH2,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 412
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CH2,HH2,TRP

HXT,TRP
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
chem comp atom.atom id: HXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 413
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TRP

N,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: N
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 414
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR

CA,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 415
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR

C,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: C
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 416
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: C,O,TYR

O,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: O
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 417
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TYR

CB,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CB
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 418
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR

CG,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CG
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 419
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CG,CD1,TYR

CD1,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 420
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CD1,CE1,TYR

CD2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 421
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD2,CE2,TYR

CE1,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 422
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CE1,CZ,TYR

CE2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 423
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CE2,CZ,TYR

CZ,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: CZ
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 424
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE1,CZ,TYR

OH,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: OH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 425
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OH,HH,TYR
referenced by chem comp bond: CZ,OH,TYR

OXT,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: OXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 426
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TYR
referenced by chem comp bond: C,OXT,TYR

H,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: H
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 427
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TYR

H2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: H2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 428
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TYR

HA,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 429
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TYR

HB2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HB2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 430
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TYR

HB3,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HB3
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 431
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TYR

HD1,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 432
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TYR

HD2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 433
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,TYR

HE1,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 434
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,TYR

HE2,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 435
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,TYR

HH,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 436
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OH,HH,TYR

HXT,TYR
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
chem comp atom.atom id: HXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 437
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TYR

N,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: N
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 438
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL

CA,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: CA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 439
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL

C,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: C
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 440
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: C,O,VAL

O,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: O
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 441
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,VAL

CB,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: CB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 442
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL

CG1,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: CG1
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 443
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL

CG2,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: CG2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 444
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL

OXT,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: OXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 445
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,VAL
referenced by chem comp bond: C,OXT,VAL

H,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: H
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 446
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,VAL

H2,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: H2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 447
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,VAL

HA,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 448
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,VAL

HB,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 449
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,VAL

HG11,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG11
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 450
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG11,VAL

HG12,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG12
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 451
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,VAL

HG13,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG13
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 452
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,VAL

HG21,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG21
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 453
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,VAL

HG22,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG22
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 454
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,VAL

HG23,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HG23
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 455
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,VAL

HXT,VAL
type: chem comp atom
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
chem comp atom.atom id: HXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 456
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,VAL

N7,C8,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N7,634
reference to chem comp atom: C8,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N7
chem comp bond.atom id 2: C8
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 1
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N7,C5,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N7,634
reference to chem comp atom: C5,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N7
chem comp bond.atom id 2: C5
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 2
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C8,C9,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C8,634
reference to chem comp atom: C9,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C8
chem comp bond.atom id 2: C9
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 3
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C12,C13,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C12,634
reference to chem comp atom: C13,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: C13
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 4
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C12,C11,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C12,634
reference to chem comp atom: C11,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: C11
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 5
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C5,N6,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C5,634
reference to chem comp atom: N6,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: N6
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 6
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C5,C4,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C5,634
reference to chem comp atom: C4,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: C4
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 7
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N6,C1,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N6,634
reference to chem comp atom: C1,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N6
chem comp bond.atom id 2: C1
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 8
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C9,C4,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C9,634
reference to chem comp atom: C4,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C9
chem comp bond.atom id 2: C4
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 9
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C4,C3,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C4,634
reference to chem comp atom: C3,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: C3
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 10
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C1,N22,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,634
reference to chem comp atom: N22,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: N22
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 11
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,N2,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,634
reference to chem comp atom: N2,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: N2
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 12
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N22,C23,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N22,634
reference to chem comp atom: C23,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N22
chem comp bond.atom id 2: C23
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 13
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,N2,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C3,634
reference to chem comp atom: N2,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: N2
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 14
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,O10,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C3,634
reference to chem comp atom: O10,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: O10
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 15
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C13,C14,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C13,634
reference to chem comp atom: C14,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C13
chem comp bond.atom id 2: C14
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 16
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C23,C27,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C23,634
reference to chem comp atom: C27,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C23
chem comp bond.atom id 2: C27
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 17
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C23,C24,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C23,634
reference to chem comp atom: C24,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C23
chem comp bond.atom id 2: C24
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 18
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

O10,C11,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O10,634
reference to chem comp atom: C11,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: O10
chem comp bond.atom id 2: C11
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 19
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C27,N26,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C27,634
reference to chem comp atom: N26,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C27
chem comp bond.atom id 2: N26
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 20
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C24,N25,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C24,634
reference to chem comp atom: N25,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C24
chem comp bond.atom id 2: N25
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 21
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N26,N25,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N26,634
reference to chem comp atom: N25,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N26
chem comp bond.atom id 2: N25
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 22
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N25,C28,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N25,634
reference to chem comp atom: C28,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N25
chem comp bond.atom id 2: C28
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 23
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C11,C16,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C11,634
reference to chem comp atom: C16,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C11
chem comp bond.atom id 2: C16
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 24
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C14,C15,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C14,634
reference to chem comp atom: C15,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C14
chem comp bond.atom id 2: C15
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 25
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C16,C15,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C16,634
reference to chem comp atom: C15,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C16
chem comp bond.atom id 2: C15
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 26
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C15,N17,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C15,634
reference to chem comp atom: N17,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C15
chem comp bond.atom id 2: N17
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 27
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N17,C18,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N17,634
reference to chem comp atom: C18,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N17
chem comp bond.atom id 2: C18
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 28
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O19,C18,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O19,634
reference to chem comp atom: C18,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: O19
chem comp bond.atom id 2: C18
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 29
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C18,C20,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C18,634
reference to chem comp atom: C20,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C18
chem comp bond.atom id 2: C20
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 30
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C20,C21,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C20,634
reference to chem comp atom: C21,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C20
chem comp bond.atom id 2: C21
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 31
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C8,H1,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C8,634
reference to chem comp atom: H1,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C8
chem comp bond.atom id 2: H1
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 32
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C13,H2,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C13,634
reference to chem comp atom: H2,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C13
chem comp bond.atom id 2: H2
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 33
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C20,H3,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C20,634
reference to chem comp atom: H3,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C20
chem comp bond.atom id 2: H3
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 34
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C20,H4,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C20,634
reference to chem comp atom: H4,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C20
chem comp bond.atom id 2: H4
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 35
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C21,H5,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C21,634
reference to chem comp atom: H5,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C21
chem comp bond.atom id 2: H5
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 36
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C21,H6,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C21,634
reference to chem comp atom: H6,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C21
chem comp bond.atom id 2: H6
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 37
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C21,H7,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C21,634
reference to chem comp atom: H7,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C21
chem comp bond.atom id 2: H7
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 38
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C24,H8,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C24,634
reference to chem comp atom: H8,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C24
chem comp bond.atom id 2: H8
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 39
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C28,H9,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C28,634
reference to chem comp atom: H9,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C28
chem comp bond.atom id 2: H9
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 40
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C28,H10,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C28,634
reference to chem comp atom: H10,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C28
chem comp bond.atom id 2: H10
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 41
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C28,H11,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C28,634
reference to chem comp atom: H11,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C28
chem comp bond.atom id 2: H11
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 42
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N7,H12,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N7,634
reference to chem comp atom: H12,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N7
chem comp bond.atom id 2: H12
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 43
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C9,H13,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C9,634
reference to chem comp atom: H13,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C9
chem comp bond.atom id 2: H13
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 44
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C12,H14,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C12,634
reference to chem comp atom: H14,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C12
chem comp bond.atom id 2: H14
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 45
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C14,H15,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C14,634
reference to chem comp atom: H15,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C14
chem comp bond.atom id 2: H15
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 46
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C16,H16,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C16,634
reference to chem comp atom: H16,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C16
chem comp bond.atom id 2: H16
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 47
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N17,H17,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N17,634
reference to chem comp atom: H17,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N17
chem comp bond.atom id 2: H17
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 48
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N22,H18,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N22,634
reference to chem comp atom: H18,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: N22
chem comp bond.atom id 2: H18
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 49
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C27,H19,634
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C27,634
reference to chem comp atom: H19,634
reference to chem comp: http://rdf.wwpdb.org/pdb/5HG8/chem_comp/634
chem comp bond.atom id 1: C27
chem comp bond.atom id 2: H19
chem comp bond.comp id: 634
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 50
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ALA
reference to chem comp atom: CA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 51
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ALA
reference to chem comp atom: H,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 52
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ALA
reference to chem comp atom: H2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 53
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ALA
reference to chem comp atom: C,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 54
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ALA
reference to chem comp atom: CB,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 55
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ALA
reference to chem comp atom: HA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 56
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ALA
reference to chem comp atom: O,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 57
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ALA
reference to chem comp atom: OXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 58
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB1,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB1,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB1
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 59
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 60
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB3,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 61
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ALA
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,ALA
reference to chem comp atom: HXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 62
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ARG
reference to chem comp atom: CA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 63
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ARG
reference to chem comp atom: H,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 64
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ARG
reference to chem comp atom: H2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 65
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ARG
reference to chem comp atom: C,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 66
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ARG
reference to chem comp atom: CB,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 67
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ARG
reference to chem comp atom: HA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 68
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ARG
reference to chem comp atom: O,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 69
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ARG
reference to chem comp atom: OXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 70
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ARG
reference to chem comp atom: CG,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 71
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 72
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 73
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ARG
reference to chem comp atom: CD,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 74
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 75
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 76
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,NE,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,ARG
reference to chem comp atom: NE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 77
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 78
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 79
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,CZ,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE,ARG
reference to chem comp atom: CZ,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: CZ
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 80
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,HE,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE,ARG
reference to chem comp atom: HE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: HE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 81
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH1,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH1,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH1
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 82
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH2,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 83
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

NH1,HH11,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH11,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH11
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 84
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH1,HH12,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH12,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH12
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 85
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH21,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH21,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH21
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 86
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH22,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH22,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH22
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 87
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ARG
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,ARG
reference to chem comp atom: HXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 88
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASN
reference to chem comp atom: CA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 89
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASN
reference to chem comp atom: H,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 90
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASN
reference to chem comp atom: H2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 91
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASN
reference to chem comp atom: C,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 92
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASN
reference to chem comp atom: CB,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 93
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASN
reference to chem comp atom: HA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 94
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ASN
reference to chem comp atom: O,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 95
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ASN
reference to chem comp atom: OXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 96
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASN
reference to chem comp atom: CG,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 97
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 98
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB3,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 99
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ASN
reference to chem comp atom: OD1,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 100
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,ND2,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ASN
reference to chem comp atom: ND2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 101
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD21,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD21,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 102
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD22,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD22,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 103
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,ASN
reference to chem comp atom: HXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 104
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASP
reference to chem comp atom: CA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 105
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASP
reference to chem comp atom: H,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 106
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ASP
reference to chem comp atom: H2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 107
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASP
reference to chem comp atom: C,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 108
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASP
reference to chem comp atom: CB,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 109
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ASP
reference to chem comp atom: HA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 110
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ASP
reference to chem comp atom: O,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 111
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ASP
reference to chem comp atom: OXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 112
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASP
reference to chem comp atom: CG,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 113
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 114
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB3,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 115
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD1,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 116
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,OD2,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 117
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OD2,HD2,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OD2,ASP
reference to chem comp atom: HD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 118
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,ASP
reference to chem comp atom: HXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 119
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,CYS
reference to chem comp atom: CA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 120
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,CYS
reference to chem comp atom: H,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 121
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,CYS
reference to chem comp atom: H2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 122
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,CYS
reference to chem comp atom: C,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 123
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,CYS
reference to chem comp atom: CB,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 124
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,CYS
reference to chem comp atom: HA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 125
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,CYS
reference to chem comp atom: O,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 126
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,CYS
reference to chem comp atom: OXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 127
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,SG,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,CYS
reference to chem comp atom: SG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: SG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 128
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 129
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB3,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 130
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SG,HG,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: SG,CYS
reference to chem comp atom: HG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: SG
chem comp bond.atom id 2: HG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 131
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,CYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,CYS
reference to chem comp atom: HXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 132
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLN
reference to chem comp atom: CA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 133
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLN
reference to chem comp atom: H,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 134
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLN
reference to chem comp atom: H2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 135
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLN
reference to chem comp atom: C,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 136
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLN
reference to chem comp atom: CB,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 137
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLN
reference to chem comp atom: HA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 138
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLN
reference to chem comp atom: O,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 139
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLN
reference to chem comp atom: OXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 140
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLN
reference to chem comp atom: CG,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 141
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 142
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 143
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLN
reference to chem comp atom: CD,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 144
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 145
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 146
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,GLN
reference to chem comp atom: OE1,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 147
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,NE2,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,GLN
reference to chem comp atom: NE2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 148
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE21,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE21,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE21
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 149
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE22,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE22,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE22
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 150
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLN
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,GLN
reference to chem comp atom: HXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 151
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLU
reference to chem comp atom: CA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 152
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLU
reference to chem comp atom: H,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 153
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLU
reference to chem comp atom: H2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 154
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLU
reference to chem comp atom: C,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 155
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLU
reference to chem comp atom: CB,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 156
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLU
reference to chem comp atom: HA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 157
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLU
reference to chem comp atom: O,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 158
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLU
reference to chem comp atom: OXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 159
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLU
reference to chem comp atom: CG,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 160
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 161
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 162
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLU
reference to chem comp atom: CD,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 163
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 164
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 165
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE1,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 166
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,OE2,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 167
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OE2,HE2,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OE2,GLU
reference to chem comp atom: HE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 168
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,GLU
reference to chem comp atom: HXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 169
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLY
reference to chem comp atom: CA,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 170
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLY
reference to chem comp atom: H,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 171
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,GLY
reference to chem comp atom: H2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 172
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLY
reference to chem comp atom: C,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 173
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA2,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 174
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA3,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA3,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA3
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 175
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLY
reference to chem comp atom: O,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 176
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,GLY
reference to chem comp atom: OXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 177
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLY
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,GLY
reference to chem comp atom: HXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 178
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,O1,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,GOL
reference to chem comp atom: O1,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: O1
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 179
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,C2,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,GOL
reference to chem comp atom: C2,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: C2
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 180
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H11,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,GOL
reference to chem comp atom: H11,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H11
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 181
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H12,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C1,GOL
reference to chem comp atom: H12,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H12
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 182
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O1,HO1,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O1,GOL
reference to chem comp atom: HO1,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: O1
chem comp bond.atom id 2: HO1
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 183
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,O2,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C2,GOL
reference to chem comp atom: O2,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: O2
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 184
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,C3,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C2,GOL
reference to chem comp atom: C3,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: C3
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 185
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,H2,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C2,GOL
reference to chem comp atom: H2,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: H2
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 186
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O2,HO2,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O2,GOL
reference to chem comp atom: HO2,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: O2
chem comp bond.atom id 2: HO2
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 187
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,O3,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C3,GOL
reference to chem comp atom: O3,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: O3
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 188
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,H31,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C3,GOL
reference to chem comp atom: H31,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: H31
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 189
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,H32,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C3,GOL
reference to chem comp atom: H32,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: H32
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 190
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O3,HO3,GOL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O3,GOL
reference to chem comp atom: HO3,GOL
reference to chem comp: GOL
chem comp bond.atom id 1: O3
chem comp bond.atom id 2: HO3
chem comp bond.comp id: GOL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 191
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,HIS
reference to chem comp atom: CA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 192
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,HIS
reference to chem comp atom: H,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 193
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,HIS
reference to chem comp atom: H2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 194
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,HIS
reference to chem comp atom: C,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 195
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,HIS
reference to chem comp atom: CB,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 196
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,HIS
reference to chem comp atom: HA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 197
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,HIS
reference to chem comp atom: O,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 198
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,HIS
reference to chem comp atom: OXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 199
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,HIS
reference to chem comp atom: CG,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 200
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 201
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB3,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 202
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,ND1,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,HIS
reference to chem comp atom: ND1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 203
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,HIS
reference to chem comp atom: CD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 204
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,CE1,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: ND1,HIS
reference to chem comp atom: CE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 205
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,HD1,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: ND1,HIS
reference to chem comp atom: HD1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 206
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,NE2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 207
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,HIS
reference to chem comp atom: HD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 208
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,NE2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 209
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,HE1,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,HIS
reference to chem comp atom: HE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 210
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE2,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE2,HIS
reference to chem comp atom: HE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 211
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,HIS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,HIS
reference to chem comp atom: HXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 212
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H1,HOH
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O,HOH
reference to chem comp atom: H1,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H1
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 213
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H2,HOH
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: O,HOH
reference to chem comp atom: H2,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H2
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 214
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ILE
reference to chem comp atom: CA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 215
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ILE
reference to chem comp atom: H,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 216
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,ILE
reference to chem comp atom: H2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 217
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ILE
reference to chem comp atom: C,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 218
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ILE
reference to chem comp atom: CB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 219
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,ILE
reference to chem comp atom: HA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 220
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ILE
reference to chem comp atom: O,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 221
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,ILE
reference to chem comp atom: OXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 222
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 223
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 224
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,ILE
reference to chem comp atom: HB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 225
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,CD1,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,ILE
reference to chem comp atom: CD1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: CD1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 226
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 227
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 228
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG21,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 229
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG22,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 230
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG23,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 231
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD11,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 232
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 233
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 234
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ILE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,ILE
reference to chem comp atom: HXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 235
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LEU
reference to chem comp atom: CA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 236
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LEU
reference to chem comp atom: H,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 237
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LEU
reference to chem comp atom: H2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 238
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LEU
reference to chem comp atom: C,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 239
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LEU
reference to chem comp atom: CB,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 240
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LEU
reference to chem comp atom: HA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 241
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,LEU
reference to chem comp atom: O,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 242
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,LEU
reference to chem comp atom: OXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 243
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LEU
reference to chem comp atom: CG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 244
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 245
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB3,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 246
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD1,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 247
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 248
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LEU
reference to chem comp atom: HG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 249
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD11,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 250
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD12,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 251
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD13,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 252
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD21,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD21,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 253
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD22,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD22,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 254
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD23,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD23,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD23
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 255
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LEU
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,LEU
reference to chem comp atom: HXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 256
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LYS
reference to chem comp atom: CA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 257
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LYS
reference to chem comp atom: H,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 258
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,LYS
reference to chem comp atom: H2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 259
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LYS
reference to chem comp atom: C,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 260
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LYS
reference to chem comp atom: CB,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 261
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,LYS
reference to chem comp atom: HA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 262
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,LYS
reference to chem comp atom: O,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 263
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,LYS
reference to chem comp atom: OXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 264
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LYS
reference to chem comp atom: CG,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 265
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 266
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 267
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LYS
reference to chem comp atom: CD,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 268
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 269
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 270
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,CE,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,LYS
reference to chem comp atom: CE,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: CE
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 271
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 272
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 273
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,NZ,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,LYS
reference to chem comp atom: NZ,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: NZ
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 274
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 275
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 276
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ1,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ1,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ1
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 277
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ2,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 278
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ3,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 279
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LYS
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,LYS
reference to chem comp atom: HXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 280
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,MET
reference to chem comp atom: CA,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 281
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,MET
reference to chem comp atom: H,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 282
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,MET
reference to chem comp atom: H2,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 283
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,MET
reference to chem comp atom: C,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 284
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,MET
reference to chem comp atom: CB,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 285
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,MET
reference to chem comp atom: HA,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 286
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,MET
reference to chem comp atom: O,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 287
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,MET
reference to chem comp atom: OXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 288
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,MET
reference to chem comp atom: CG,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 289
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,MET
reference to chem comp atom: HB2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 290
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,MET
reference to chem comp atom: HB3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 291
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,SD,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,MET
reference to chem comp atom: SD,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: SD
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 292
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,MET
reference to chem comp atom: HG2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 293
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,MET
reference to chem comp atom: HG3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 294
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SD,CE,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: SD,MET
reference to chem comp atom: CE,MET
reference to chem comp: MET
chem comp bond.atom id 1: SD
chem comp bond.atom id 2: CE
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 295
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE1,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,MET
reference to chem comp atom: HE1,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE1
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 296
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,MET
reference to chem comp atom: HE2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 297
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE,MET
reference to chem comp atom: HE3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 298
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,MET
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,MET
reference to chem comp atom: HXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 299
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PHE
reference to chem comp atom: CA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 300
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PHE
reference to chem comp atom: H,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 301
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PHE
reference to chem comp atom: H2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 302
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PHE
reference to chem comp atom: C,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 303
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PHE
reference to chem comp atom: CB,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 304
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PHE
reference to chem comp atom: HA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 305
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,PHE
reference to chem comp atom: O,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 306
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,PHE
reference to chem comp atom: OXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 307
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PHE
reference to chem comp atom: CG,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 308
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 309
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB3,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 310
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 311
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 312
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,PHE
reference to chem comp atom: CE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 313
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,PHE
reference to chem comp atom: HD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 314
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,PHE
reference to chem comp atom: CE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 315
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,PHE
reference to chem comp atom: HD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 316
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 317
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,PHE
reference to chem comp atom: HE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 318
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE2,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 319
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE2,PHE
reference to chem comp atom: HE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 320
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,HZ,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ,PHE
reference to chem comp atom: HZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: HZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 321
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PHE
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,PHE
reference to chem comp atom: HXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 322
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PRO
reference to chem comp atom: CA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 323
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CD,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 324
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,PRO
reference to chem comp atom: H,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 325
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PRO
reference to chem comp atom: C,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 326
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PRO
reference to chem comp atom: CB,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 327
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,PRO
reference to chem comp atom: HA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 328
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,PRO
reference to chem comp atom: O,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 329
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,PRO
reference to chem comp atom: OXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 330
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PRO
reference to chem comp atom: CG,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 331
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 332
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 333
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 334
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 335
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 336
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 337
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 338
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PRO
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,PRO
reference to chem comp atom: HXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 339
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,SER
reference to chem comp atom: CA,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 340
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,SER
reference to chem comp atom: H,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 341
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,SER
reference to chem comp atom: H2,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 342
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,SER
reference to chem comp atom: C,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 343
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,SER
reference to chem comp atom: CB,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 344
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,SER
reference to chem comp atom: HA,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 345
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,SER
reference to chem comp atom: O,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 346
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,SER
reference to chem comp atom: OXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 347
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,SER
reference to chem comp atom: OG,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 348
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,SER
reference to chem comp atom: HB2,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 349
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,SER
reference to chem comp atom: HB3,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 350
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG,HG,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OG,SER
reference to chem comp atom: HG,SER
reference to chem comp: SER
chem comp bond.atom id 1: OG
chem comp bond.atom id 2: HG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 351
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,SER
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,SER
reference to chem comp atom: HXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 352
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

S,O1,SO4
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: S,SO4
reference to chem comp atom: O1,SO4
reference to chem comp: SO4
chem comp bond.atom id 1: S
chem comp bond.atom id 2: O1
chem comp bond.comp id: SO4
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 353
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

S,O2,SO4
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: S,SO4
reference to chem comp atom: O2,SO4
reference to chem comp: SO4
chem comp bond.atom id 1: S
chem comp bond.atom id 2: O2
chem comp bond.comp id: SO4
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 354
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

S,O3,SO4
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: S,SO4
reference to chem comp atom: O3,SO4
reference to chem comp: SO4
chem comp bond.atom id 1: S
chem comp bond.atom id 2: O3
chem comp bond.comp id: SO4
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 355
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

S,O4,SO4
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: S,SO4
reference to chem comp atom: O4,SO4
reference to chem comp: SO4
chem comp bond.atom id 1: S
chem comp bond.atom id 2: O4
chem comp bond.comp id: SO4
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 356
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,THR
reference to chem comp atom: CA,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 357
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,THR
reference to chem comp atom: H,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 358
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,THR
reference to chem comp atom: H2,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 359
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,THR
reference to chem comp atom: C,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 360
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,THR
reference to chem comp atom: CB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 361
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,THR
reference to chem comp atom: HA,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 362
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,THR
reference to chem comp atom: O,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 363
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,THR
reference to chem comp atom: OXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 364
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG1,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,THR
reference to chem comp atom: OG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 365
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,THR
reference to chem comp atom: CG2,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 366
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,THR
reference to chem comp atom: HB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 367
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG1,HG1,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OG1,THR
reference to chem comp atom: HG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: OG1
chem comp bond.atom id 2: HG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 368
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG21,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 369
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG22,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 370
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG23,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 371
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,THR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,THR
reference to chem comp atom: HXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 372
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TRP
reference to chem comp atom: CA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 373
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TRP
reference to chem comp atom: H,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 374
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TRP
reference to chem comp atom: H2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 375
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TRP
reference to chem comp atom: C,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 376
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TRP
reference to chem comp atom: CB,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 377
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TRP
reference to chem comp atom: HA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 378
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,TRP
reference to chem comp atom: O,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 379
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,TRP
reference to chem comp atom: OXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 380
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TRP
reference to chem comp atom: CG,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 381
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 382
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 383
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 384
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 385
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,NE1,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,TRP
reference to chem comp atom: NE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: NE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 386
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,TRP
reference to chem comp atom: HD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 387
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 388
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,CE3,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 389
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,CE2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE1,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 390
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,HE1,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: NE1,TRP
reference to chem comp atom: HE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 391
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE2,TRP
reference to chem comp atom: CZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 392
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE3,CZ3,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE3,TRP
reference to chem comp atom: CZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: CZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 393
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE3,HE3,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE3,TRP
reference to chem comp atom: HE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: HE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 394
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ2,CH2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 395
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CZ2,HZ2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: HZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 396
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,CH2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 397
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,HZ3,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: HZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 398
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CH2,HH2,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CH2,TRP
reference to chem comp atom: HH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CH2
chem comp bond.atom id 2: HH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 399
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TRP
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,TRP
reference to chem comp atom: HXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 400
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TYR
reference to chem comp atom: CA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 401
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TYR
reference to chem comp atom: H,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 402
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,TYR
reference to chem comp atom: H2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 403
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TYR
reference to chem comp atom: C,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 404
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TYR
reference to chem comp atom: CB,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 405
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,TYR
reference to chem comp atom: HA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 406
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,TYR
reference to chem comp atom: O,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 407
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,TYR
reference to chem comp atom: OXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 408
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TYR
reference to chem comp atom: CG,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 409
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 410
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB3,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 411
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 412
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 413
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,TYR
reference to chem comp atom: CE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 414
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD1,TYR
reference to chem comp atom: HD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 415
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,TYR
reference to chem comp atom: CE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 416
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CD2,TYR
reference to chem comp atom: HD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 417
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 418
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE1,TYR
reference to chem comp atom: HE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 419
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE2,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 420
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CE2,TYR
reference to chem comp atom: HE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 421
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,OH,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CZ,TYR
reference to chem comp atom: OH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: OH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 422
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OH,HH,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OH,TYR
reference to chem comp atom: HH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OH
chem comp bond.atom id 2: HH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 423
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TYR
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,TYR
reference to chem comp atom: HXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 424
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,VAL
reference to chem comp atom: CA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 425
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,VAL
reference to chem comp atom: H,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 426
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: N,VAL
reference to chem comp atom: H2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 427
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,VAL
reference to chem comp atom: C,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 428
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,VAL
reference to chem comp atom: CB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 429
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CA,VAL
reference to chem comp atom: HA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 430
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,VAL
reference to chem comp atom: O,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 431
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: C,VAL
reference to chem comp atom: OXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 432
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG1,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 433
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 434
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CB,VAL
reference to chem comp atom: HB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 435
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG11,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG11,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG11
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 436
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG12,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 437
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG13,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 438
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG21,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 439
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG22,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 440
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG23,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 441
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,VAL
type: chem comp bond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp atom: OXT,VAL
reference to chem comp atom: HXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 442
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

primary
type: citation
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
citation.id: primary
citation.country: US
citation.journal abbrev: J.Med.Chem.
citation.journal id ASTM: JMCMAR
citation.journal id CSD: 0151
citation.journal id ISSN: 0022-2623
citation.journal volume: 59
citation.page first: 2005
citation.page last: 2024
citation.pdbx database id DOI: 10.1021/acs.jmedchem.5b01633
citation.pdbx database id pub med: 26756222
citation.title: Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
citation.year: 2016
link to doi: doi:10.1021/acs.jmedchem.5b01633
link to pubmed: pubmed:26756222
references: pubmed:26756222
referenced by citation author: primary,Kath, J.C.,51
referenced by citation author: primary,Cheng, H.,1
referenced by citation author: primary,Nair, S.K.,2
referenced by citation author: primary,Murray, B.W.,3
referenced by citation author: primary,Almaden, C.,4
referenced by citation author: primary,Bailey, S.,5
referenced by citation author: primary,Baxi, S.,6
referenced by citation author: primary,Behenna, D.,7
referenced by citation author: primary,Cho-Schultz, S.,8
referenced by citation author: primary,Dalvie, D.,9
referenced by citation author: primary,Dinh, D.M.,10
referenced by citation author: primary,Edwards, M.P.,11
referenced by citation author: primary,Feng, J.L.,12
referenced by citation author: primary,Ferre, R.A.,13
referenced by citation author: primary,Gajiwala, K.S.,14
referenced by citation author: primary,Hemkens, M.D.,15
referenced by citation author: primary,Jackson-Fisher, A.,16
referenced by citation author: primary,Jalaie, M.,17
referenced by citation author: primary,Johnson, T.O.,18
referenced by citation author: primary,Kania, R.S.,19
referenced by citation author: primary,Kephart, S.,20
referenced by citation author: primary,Lafontaine, J.,21
referenced by citation author: primary,Lunney, B.,22
referenced by citation author: primary,Liu, K.K.,23
referenced by citation author: primary,Liu, Z.,24
referenced by citation author: primary,Matthews, J.,25
referenced by citation author: primary,Nagata, A.,26
referenced by citation author: primary,Niessen, S.,27
referenced by citation author: primary,Ornelas, M.A.,28
referenced by citation author: primary,Orr, S.T.,29
referenced by citation author: primary,Pairish, M.,30
referenced by citation author: primary,Planken, S.,31
referenced by citation author: primary,Ren, S.,32
referenced by citation author: primary,Richter, D.,33
referenced by citation author: primary,Ryan, K.,34
referenced by citation author: primary,Sach, N.,35
referenced by citation author: primary,Shen, H.,36
referenced by citation author: primary,Smeal, T.,37
referenced by citation author: primary,Solowiej, J.,38
referenced by citation author: primary,Sutton, S.,39
referenced by citation author: primary,Tran, K.,40
referenced by citation author: primary,Tseng, E.,41
referenced by citation author: primary,Vernier, W.,42
referenced by citation author: primary,Walls, M.,43
referenced by citation author: primary,Wang, S.,44
referenced by citation author: primary,Weinrich, S.L.,45
referenced by citation author: primary,Xin, S.,46
referenced by citation author: primary,Xu, H.,47
referenced by citation author: primary,Yin, M.J.,48
referenced by citation author: primary,Zientek, M.,49
referenced by citation author: primary,Zhou, R.,50

primary,Cheng, H.,1
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Cheng, H.
citation author.ordinal: 1

primary,Nair, S.K.,2
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Nair, S.K.
citation author.ordinal: 2

primary,Murray, B.W.,3
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Murray, B.W.
citation author.ordinal: 3

primary,Almaden, C.,4
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Almaden, C.
citation author.ordinal: 4

primary,Bailey, S.,5
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Bailey, S.
citation author.ordinal: 5

primary,Baxi, S.,6
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Baxi, S.
citation author.ordinal: 6

primary,Behenna, D.,7
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Behenna, D.
citation author.ordinal: 7

primary,Cho-Schultz, S.,8
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Cho-Schultz, S.
citation author.ordinal: 8

primary,Dalvie, D.,9
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Dalvie, D.
citation author.ordinal: 9

primary,Dinh, D.M.,10
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Dinh, D.M.
citation author.ordinal: 10

primary,Edwards, M.P.,11
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Edwards, M.P.
citation author.ordinal: 11

primary,Feng, J.L.,12
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Feng, J.L.
citation author.ordinal: 12

primary,Ferre, R.A.,13
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Ferre, R.A.
citation author.ordinal: 13

primary,Gajiwala, K.S.,14
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Gajiwala, K.S.
citation author.ordinal: 14

primary,Hemkens, M.D.,15
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Hemkens, M.D.
citation author.ordinal: 15

primary,Jackson-Fisher, A.,16
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Jackson-Fisher, A.
citation author.ordinal: 16

primary,Jalaie, M.,17
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Jalaie, M.
citation author.ordinal: 17

primary,Johnson, T.O.,18
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Johnson, T.O.
citation author.ordinal: 18

primary,Kania, R.S.,19
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Kania, R.S.
citation author.ordinal: 19

primary,Kephart, S.,20
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Kephart, S.
citation author.ordinal: 20

primary,Lafontaine, J.,21
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Lafontaine, J.
citation author.ordinal: 21

primary,Lunney, B.,22
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Lunney, B.
citation author.ordinal: 22

primary,Liu, K.K.,23
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Liu, K.K.
citation author.ordinal: 23

primary,Liu, Z.,24
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Liu, Z.
citation author.ordinal: 24

primary,Matthews, J.,25
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Matthews, J.
citation author.ordinal: 25

primary,Nagata, A.,26
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Nagata, A.
citation author.ordinal: 26

primary,Niessen, S.,27
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Niessen, S.
citation author.ordinal: 27

primary,Ornelas, M.A.,28
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Ornelas, M.A.
citation author.ordinal: 28

primary,Orr, S.T.,29
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Orr, S.T.
citation author.ordinal: 29

primary,Pairish, M.,30
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Pairish, M.
citation author.ordinal: 30

primary,Planken, S.,31
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Planken, S.
citation author.ordinal: 31

primary,Ren, S.,32
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Ren, S.
citation author.ordinal: 32

primary,Richter, D.,33
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Richter, D.
citation author.ordinal: 33

primary,Ryan, K.,34
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Ryan, K.
citation author.ordinal: 34

primary,Sach, N.,35
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Sach, N.
citation author.ordinal: 35

primary,Shen, H.,36
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Shen, H.
citation author.ordinal: 36

primary,Smeal, T.,37
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Smeal, T.
citation author.ordinal: 37

primary,Solowiej, J.,38
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Solowiej, J.
citation author.ordinal: 38

primary,Sutton, S.,39
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Sutton, S.
citation author.ordinal: 39

primary,Tran, K.,40
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Tran, K.
citation author.ordinal: 40

primary,Tseng, E.,41
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Tseng, E.
citation author.ordinal: 41

primary,Vernier, W.,42
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Vernier, W.
citation author.ordinal: 42

primary,Walls, M.,43
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Walls, M.
citation author.ordinal: 43

primary,Wang, S.,44
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Wang, S.
citation author.ordinal: 44

primary,Weinrich, S.L.,45
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Weinrich, S.L.
citation author.ordinal: 45

primary,Xin, S.,46
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Xin, S.
citation author.ordinal: 46

primary,Xu, H.,47
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Xu, H.
citation author.ordinal: 47

primary,Yin, M.J.,48
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Yin, M.J.
citation author.ordinal: 48

primary,Zientek, M.,49
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Zientek, M.
citation author.ordinal: 49

primary,Zhou, R.,50
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Zhou, R.
citation author.ordinal: 50

primary,Kath, J.C.,51
type: citation author
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Kath, J.C.
citation author.ordinal: 51

5HG8,PDB
type: database 2
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
database 2.database code: 5HG8
database 2.database id: PDB
database 2.pdbx DOI: 10.2210/pdb5hg8/pdb
database 2.pdbx database accession: pdb_00005hg8

D 1000216988,WWPDB
type: database 2
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
database 2.database code: D_1000216988
database 2.database id: WWPDB

5HG8
type: database PDB matrix
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
database PDB matrix.entry id: 5HG8
database PDB matrix.origx11: 1
database PDB matrix.origx12: 0
database PDB matrix.origx13: 0
database PDB matrix.origx21: 0
database PDB matrix.origx22: 1
database PDB matrix.origx23: 0
database PDB matrix.origx31: 0
database PDB matrix.origx32: 0
database PDB matrix.origx33: 1
database PDB matrix.origx vector1: 0
database PDB matrix.origx vector2: 0
database PDB matrix.origx vector3: 0

http://rdf.wwpdb.org/pdb/5HG8/diffrn/1
type: diffrn
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to exptl crystal: http://rdf.wwpdb.org/pdb/5HG8/exptl_crystal/1
diffrn.id: 1
diffrn.ambient temp: 98
diffrn.crystal id: 1
referenced by diffrn detector: http://rdf.wwpdb.org/pdb/5HG8/diffrn_detector/1
referenced by diffrn radiation: http://rdf.wwpdb.org/pdb/5HG8/diffrn_radiation/1
referenced by diffrn source: http://rdf.wwpdb.org/pdb/5HG8/diffrn_source/1

http://rdf.wwpdb.org/pdb/5HG8/exptl_crystal/1
referenced by diffrn: http://rdf.wwpdb.org/pdb/5HG8/diffrn/1
type: exptl crystal
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
exptl crystal.id: 1
exptl crystal.density matthews: 2.05
exptl crystal.density percent sol: 39.97
referenced by exptl crystal grow: http://rdf.wwpdb.org/pdb/5HG8/exptl_crystal_grow/1

http://rdf.wwpdb.org/pdb/5HG8/diffrn_detector/1
type: diffrn detector
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to diffrn: http://rdf.wwpdb.org/pdb/5HG8/diffrn/1
diffrn detector.diffrn id: 1
diffrn detector.detector: PIXEL
diffrn detector.pdbx collection date: 2012-04-19
diffrn detector.type: DECTRIS PILATUS 6M

http://rdf.wwpdb.org/pdb/5HG8/diffrn_radiation/1
type: diffrn radiation
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to diffrn: http://rdf.wwpdb.org/pdb/5HG8/diffrn/1
diffrn radiation.diffrn id: 1
diffrn radiation.pdbx diffrn protocol: SINGLE WAVELENGTH
diffrn radiation.pdbx monochromatic or laue m l: M
diffrn radiation.pdbx scattering type: x-ray
diffrn radiation.wavelength id: 1

http://rdf.wwpdb.org/pdb/5HG8/diffrn_radiation_wavelength/1
type: diffrn radiation wavelength
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
diffrn radiation wavelength.id: 1
diffrn radiation wavelength.wavelength: 1
diffrn radiation wavelength.wt: 1

http://rdf.wwpdb.org/pdb/5HG8/diffrn_source/1
type: diffrn source
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to diffrn: http://rdf.wwpdb.org/pdb/5HG8/diffrn/1
diffrn source.diffrn id: 1
diffrn source.pdbx synchrotron beamline: 17-ID
diffrn source.pdbx synchrotron site: APS
diffrn source.pdbx wavelength list: 1.0
diffrn source.source: SYNCHROTRON
diffrn source.type: APS BEAMLINE 17-ID

http://rdf.wwpdb.org/pdb/5HG8/entity/1
type: entity
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entity.id: 1
entity.formula weight: 37580.453
entity.pdbx description: Epidermal growth factor receptor
entity.pdbx ec: 2.7.10.1
entity.pdbx fragment: UNP residues 695-1022
entity.pdbx mutation: L858R, T790M, V948R
entity.pdbx number of molecules: 1
entity.src method: man
entity.type: polymer
link to enzyme: enzyme:2.7.10.1
referenced by entity name com: http://rdf.wwpdb.org/pdb/5HG8/entity_name_com/1
referenced by entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
referenced by struct ref: http://rdf.wwpdb.org/pdb/5HG8/struct_ref/1
referenced by entity src gen: 1,1

ec-code:2.7.10.1

http://rdf.wwpdb.org/pdb/5HG8/entity/2
type: entity
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entity.id: 2
entity.formula weight: 377.4
entity.pdbx description: N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide
entity.pdbx number of molecules: 1
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/B
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/2

http://rdf.wwpdb.org/pdb/5HG8/entity/3
type: entity
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entity.id: 3
entity.formula weight: 96.063
entity.pdbx description: SULFATE ION
entity.pdbx number of molecules: 2
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/D
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/3
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/C

http://rdf.wwpdb.org/pdb/5HG8/entity/4
type: entity
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entity.id: 4
entity.formula weight: 92.094
entity.pdbx description: GLYCEROL
entity.pdbx number of molecules: 1
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/E
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/4

http://rdf.wwpdb.org/pdb/5HG8/entity/5
type: entity
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
entity.id: 5
entity.formula weight: 18.015
entity.pdbx description: water
entity.pdbx number of molecules: 209
entity.src method: nat
entity.type: water
referenced by struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/F
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/5

http://rdf.wwpdb.org/pdb/5HG8/entity_name_com/1
type: entity name com
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/1
entity name com.entity id: 1
entity name com.name: Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1

http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
type: entity poly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/1
entity poly.entity id: 1
entity poly.nstd linkage: no
entity poly.nstd monomer: no
entity poly.pdbx seq one letter code: GSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPH VCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI TDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERL PQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDA DEYLIPQQG
entity poly.pdbx seq one letter code can: GSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPH VCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI TDFGRAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERL PQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDA DEYLIPQQG
entity poly.pdbx strand id: A
entity poly.type: polypeptide(L)
referenced by entity poly seq: 1,GLY,329
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,SER,2
referenced by entity poly seq: 1,GLY,3
referenced by entity poly seq: 1,GLU,4
referenced by entity poly seq: 1,ALA,5
referenced by entity poly seq: 1,PRO,6
referenced by entity poly seq: 1,ASN,7
referenced by entity poly seq: 1,GLN,8
referenced by entity poly seq: 1,ALA,9
referenced by entity poly seq: 1,LEU,10
referenced by entity poly seq: 1,LEU,11
referenced by entity poly seq: 1,ARG,12
referenced by entity poly seq: 1,ILE,13
referenced by entity poly seq: 1,LEU,14
referenced by entity poly seq: 1,LYS,15
referenced by entity poly seq: 1,GLU,16
referenced by entity poly seq: 1,THR,17
referenced by entity poly seq: 1,GLU,18
referenced by entity poly seq: 1,PHE,19
referenced by entity poly seq: 1,LYS,20
referenced by entity poly seq: 1,LYS,21
referenced by entity poly seq: 1,ILE,22
referenced by entity poly seq: 1,LYS,23
referenced by entity poly seq: 1,VAL,24
referenced by entity poly seq: 1,LEU,25
referenced by entity poly seq: 1,GLY,26
referenced by entity poly seq: 1,SER,27
referenced by entity poly seq: 1,GLY,28
referenced by entity poly seq: 1,ALA,29
referenced by entity poly seq: 1,PHE,30
referenced by entity poly seq: 1,GLY,31
referenced by entity poly seq: 1,THR,32
referenced by entity poly seq: 1,VAL,33
referenced by entity poly seq: 1,TYR,34
referenced by entity poly seq: 1,LYS,35
referenced by entity poly seq: 1,GLY,36
referenced by entity poly seq: 1,LEU,37
referenced by entity poly seq: 1,TRP,38
referenced by entity poly seq: 1,ILE,39
referenced by entity poly seq: 1,PRO,40
referenced by entity poly seq: 1,GLU,41
referenced by entity poly seq: 1,GLY,42
referenced by entity poly seq: 1,GLU,43
referenced by entity poly seq: 1,LYS,44
referenced by entity poly seq: 1,VAL,45
referenced by entity poly seq: 1,LYS,46
referenced by entity poly seq: 1,ILE,47
referenced by entity poly seq: 1,PRO,48
referenced by entity poly seq: 1,VAL,49
referenced by entity poly seq: 1,ALA,50
referenced by entity poly seq: 1,ILE,51
referenced by entity poly seq: 1,LYS,52
referenced by entity poly seq: 1,GLU,53
referenced by entity poly seq: 1,LEU,54
referenced by entity poly seq: 1,ARG,55
referenced by entity poly seq: 1,GLU,56
referenced by entity poly seq: 1,ALA,57
referenced by entity poly seq: 1,THR,58
referenced by entity poly seq: 1,SER,59
referenced by entity poly seq: 1,PRO,60
referenced by entity poly seq: 1,LYS,61
referenced by entity poly seq: 1,ALA,62
referenced by entity poly seq: 1,ASN,63
referenced by entity poly seq: 1,LYS,64
referenced by entity poly seq: 1,GLU,65
referenced by entity poly seq: 1,ILE,66
referenced by entity poly seq: 1,LEU,67
referenced by entity poly seq: 1,ASP,68
referenced by entity poly seq: 1,GLU,69

1,GLY,1
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 1
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,1

1,SER,2
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 2
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,2

1,GLY,3
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 3
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,3

1,GLU,4
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 4
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,4

1,ALA,5
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 5
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,5

1,PRO,6
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 6
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,6

1,ASN,7
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 7
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,7

1,GLN,8
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 8
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,8

1,ALA,9
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 9
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,9

1,LEU,10
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 10
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,10

1,LEU,11
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 11
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,11

1,ARG,12
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 12
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,12

1,ILE,13
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 13
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,13

1,LEU,14
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 14
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,14

1,LYS,15
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 15
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,15

1,GLU,16
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 16
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,16

1,THR,17
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 17
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,17

1,GLU,18
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 18
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,18

1,PHE,19
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 19
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,19

1,LYS,20
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 20
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,20

1,LYS,21
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 21
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,21

1,ILE,22
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 22
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,22

1,LYS,23
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 23
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,23

1,VAL,24
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 24
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,24

1,LEU,25
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 25
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,25

1,GLY,26
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 26
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,26

1,SER,27
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 27
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,27

1,GLY,28
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 28
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,28

1,ALA,29
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 29
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,29

1,PHE,30
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 30
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,30

1,GLY,31
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 31
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,31

1,THR,32
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 32
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,32

1,VAL,33
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 33
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,33

1,TYR,34
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 34
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,34

1,LYS,35
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 35
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,35

1,GLY,36
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 36
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,36

1,LEU,37
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 37
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,37

1,TRP,38
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 38
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,38

1,ILE,39
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 39
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,39

1,PRO,40
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 40
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,40

1,GLU,41
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 41
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,41

1,GLY,42
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 42
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,42

1,GLU,43
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 43
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,43

1,LYS,44
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 44
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,44

1,VAL,45
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 45
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,45

1,LYS,46
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 46
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,46

1,ILE,47
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 47
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,47

1,PRO,48
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 48
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,48

1,VAL,49
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 49
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,49

1,ALA,50
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 50
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,50

1,ILE,51
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 51
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,51

1,LYS,52
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 52
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,52

1,GLU,53
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 53
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,53

1,LEU,54
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 54
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,54

1,ARG,55
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 55
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,55

1,GLU,56
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 56
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,56

1,ALA,57
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 57
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,57

1,THR,58
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 58
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,58

1,SER,59
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 59
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,59

1,PRO,60
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 60
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,60

1,LYS,61
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 61
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,61

1,ALA,62
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 62
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,62

1,ASN,63
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 63
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,63

1,LYS,64
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 64
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,64

1,GLU,65
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 65
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,65

1,ILE,66
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 66
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,66

1,LEU,67
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 67
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,67

1,ASP,68
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 68
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,68

1,GLU,69
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 69
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,69

1,ALA,70
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 70
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,70

1,TYR,71
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 71
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,71

1,VAL,72
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 72
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,72

1,MET,73
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 73
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,73

1,ALA,74
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 74
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,74

1,SER,75
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 75
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,75

1,VAL,76
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 76
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,76

1,ASP,77
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 77
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,77

1,ASN,78
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 78
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,78

1,PRO,79
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 79
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,79

1,HIS,80
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 80
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,80

1,VAL,81
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 81
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,81

1,CYS,82
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 82
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,82

1,ARG,83
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 83
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,83

1,LEU,84
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 84
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,84

1,LEU,85
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 85
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,85

1,GLY,86
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 86
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,86

1,ILE,87
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 87
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,87

1,CYS,88
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 88
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,88

1,LEU,89
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 89
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,89

1,THR,90
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 90
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,90

1,SER,91
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 91
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,91

1,THR,92
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 92
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,92

1,VAL,93
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 93
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,93

1,GLN,94
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 94
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,94

1,LEU,95
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 95
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,95

1,ILE,96
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 96
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,96

1,MET,97
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 97
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,97

1,GLN,98
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 98
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,98

1,LEU,99
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 99
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,99

1,MET,100
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 100
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,100

1,PRO,101
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 101
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,101

1,PHE,102
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 102
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,102

1,GLY,103
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 103
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,103

1,CYS,104
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 104
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,104

1,LEU,105
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 105
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,105

1,LEU,106
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 106
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,106

1,ASP,107
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 107
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,107

1,TYR,108
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 108
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,108

1,VAL,109
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 109
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,109

1,ARG,110
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 110
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,110

1,GLU,111
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 111
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,111

1,HIS,112
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 112
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,112

1,LYS,113
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 113
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,113

1,ASP,114
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 114
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,114

1,ASN,115
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 115
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,115

1,ILE,116
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 116
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,116

1,GLY,117
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 117
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,117

1,SER,118
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 118
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,118

1,GLN,119
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 119
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,119

1,TYR,120
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 120
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,120

1,LEU,121
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 121
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,121

1,LEU,122
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 122
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,122

1,ASN,123
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 123
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,123

1,TRP,124
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 124
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,124

1,CYS,125
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 125
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,125

1,VAL,126
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 126
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,126

1,GLN,127
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 127
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,127

1,ILE,128
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 128
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,128

1,ALA,129
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 129
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,129

1,LYS,130
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 130
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,130

1,GLY,131
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 131
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,131

1,MET,132
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 132
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,132

1,ASN,133
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 133
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,133

1,TYR,134
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 134
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,134

1,LEU,135
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 135
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,135

1,GLU,136
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 136
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,136

1,ASP,137
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 137
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,137

1,ARG,138
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 138
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,138

1,ARG,139
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 139
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,139

1,LEU,140
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 140
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,140

1,VAL,141
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 141
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,141

1,HIS,142
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 142
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,142

1,ARG,143
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 143
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,143

1,ASP,144
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 144
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,144

1,LEU,145
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 145
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,145

1,ALA,146
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 146
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,146

1,ALA,147
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 147
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,147

1,ARG,148
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 148
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,148

1,ASN,149
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 149
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,149

1,VAL,150
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 150
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,150

1,LEU,151
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 151
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,151

1,VAL,152
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 152
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,152

1,LYS,153
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 153
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,153

1,THR,154
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 154
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,154

1,PRO,155
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 155
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,155

1,GLN,156
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 156
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,156

1,HIS,157
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 157
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,157

1,VAL,158
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 158
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,158

1,LYS,159
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 159
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,159

1,ILE,160
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 160
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,160

1,THR,161
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 161
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,161

1,ASP,162
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 162
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,162

1,PHE,163
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 163
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,163

1,GLY,164
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 164
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,164

1,ARG,165
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 165
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,165

1,ALA,166
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 166
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,166

1,LYS,167
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 167
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,167

1,LEU,168
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 168
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,168

1,LEU,169
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 169
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,169

1,GLY,170
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 170
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,170

1,ALA,171
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 171
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,171

1,GLU,172
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 172
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,172

1,GLU,173
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 173
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,173

1,LYS,174
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 174
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,174

1,GLU,175
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 175
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,175

1,TYR,176
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 176
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,176

1,HIS,177
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 177
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,177

1,ALA,178
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 178
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,178

1,GLU,179
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 179
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,179

1,GLY,180
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 180
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,180

1,GLY,181
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 181
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,181

1,LYS,182
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 182
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,182

1,VAL,183
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 183
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,183

1,PRO,184
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 184
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,184

1,ILE,185
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 185
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,185

1,LYS,186
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 186
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,186

1,TRP,187
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 187
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,187

1,MET,188
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 188
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,188

1,ALA,189
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 189
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,189

1,LEU,190
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 190
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,190

1,GLU,191
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 191
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,191

1,SER,192
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 192
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,192

1,ILE,193
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 193
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,193

1,LEU,194
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 194
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,194

1,HIS,195
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 195
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,195

1,ARG,196
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 196
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,196

1,ILE,197
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 197
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,197

1,TYR,198
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 198
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,198

1,THR,199
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 199
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,199

1,HIS,200
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 200
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,200

1,GLN,201
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 201
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,201

1,SER,202
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 202
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,202

1,ASP,203
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 203
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,203

1,VAL,204
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 204
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,204

1,TRP,205
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 205
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,205

1,SER,206
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 206
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,206

1,TYR,207
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 207
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,207

1,GLY,208
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 208
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,208

1,VAL,209
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 209
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,209

1,THR,210
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 210
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,210

1,VAL,211
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 211
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,211

1,TRP,212
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 212
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,212

1,GLU,213
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 213
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,213

1,LEU,214
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 214
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,214

1,MET,215
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 215
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,215

1,THR,216
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 216
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,216

1,PHE,217
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 217
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,217

1,GLY,218
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 218
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,218

1,SER,219
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 219
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,219

1,LYS,220
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 220
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,220

1,PRO,221
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 221
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,221

1,TYR,222
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 222
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,222

1,ASP,223
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 223
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,223

1,GLY,224
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 224
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,224

1,ILE,225
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 225
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,225

1,PRO,226
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 226
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,226

1,ALA,227
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 227
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,227

1,SER,228
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 228
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,228

1,GLU,229
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 229
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,229

1,ILE,230
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 230
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,230

1,SER,231
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 231
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,231

1,SER,232
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 232
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,232

1,ILE,233
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 233
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,233

1,LEU,234
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 234
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,234

1,GLU,235
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 235
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,235

1,LYS,236
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 236
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,236

1,GLY,237
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 237
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,237

1,GLU,238
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 238
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,238

1,ARG,239
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 239
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,239

1,LEU,240
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 240
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,240

1,PRO,241
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 241
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,241

1,GLN,242
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 242
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,242

1,PRO,243
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 243
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,243

1,PRO,244
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 244
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,244

1,ILE,245
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 245
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,245

1,CYS,246
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 246
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,246

1,THR,247
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 247
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,247

1,ILE,248
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 248
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,248

1,ASP,249
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 249
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,249

1,VAL,250
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 250
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,250

1,TYR,251
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 251
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,251

1,MET,252
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 252
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,252

1,ILE,253
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 253
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,253

1,MET,254
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 254
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,254

1,ARG,255
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 255
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,255

1,LYS,256
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 256
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,256

1,CYS,257
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 257
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,257

1,TRP,258
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 258
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,258

1,MET,259
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 259
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,259

1,ILE,260
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 260
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,260

1,ASP,261
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 261
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,261

1,ALA,262
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 262
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,262

1,ASP,263
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 263
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,263

1,SER,264
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 264
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,264

1,ARG,265
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 265
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,265

1,PRO,266
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 266
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,266

1,LYS,267
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 267
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,267

1,PHE,268
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 268
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,268

1,ARG,269
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 269
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,269

1,GLU,270
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 270
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,270

1,LEU,271
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 271
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,271

1,ILE,272
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 272
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,272

1,ILE,273
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 273
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,273

1,GLU,274
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 274
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,274

1,PHE,275
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 275
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,275

1,SER,276
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 276
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,276

1,LYS,277
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 277
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,277

1,MET,278
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 278
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,278

1,ALA,279
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 279
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,279

1,ARG,280
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 280
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,280

1,ASP,281
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 281
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,281

1,PRO,282
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 282
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,282

1,GLN,283
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 283
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,283

1,ARG,284
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 284
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,284

1,TYR,285
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 285
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,285

1,LEU,286
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 286
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,286

1,VAL,287
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 287
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,287

1,ILE,288
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 288
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,288

1,GLN,289
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 289
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,289

1,GLY,290
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 290
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,290

1,ASP,291
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 291
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,291

1,GLU,292
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 292
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,292

1,ARG,293
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 293
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,293

1,MET,294
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 294
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,294

1,HIS,295
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 295
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,295

1,LEU,296
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 296
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,296

1,PRO,297
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 297
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,297

1,SER,298
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 298
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,298

1,PRO,299
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 299
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,299

1,THR,300
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 300
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,300

1,ASP,301
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 301
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,301

1,SER,302
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 302
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,302

1,ASN,303
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 303
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,303

1,PHE,304
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 304
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,304

1,TYR,305
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 305
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,305

1,ARG,306
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 306
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,306

1,ALA,307
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 307
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,307

1,LEU,308
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 308
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,308

1,MET,309
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 309
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,309

1,ASP,310
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 310
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,310

1,GLU,311
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 311
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,311

1,GLU,312
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 312
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,312

1,ASP,313
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 313
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,313

1,MET,314
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 314
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,314

1,ASP,315
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 315
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,315

1,ASP,316
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 316
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,316

1,VAL,317
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 317
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,317

1,VAL,318
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 318
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,318

1,ASP,319
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 319
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,319

1,ALA,320
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 320
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,320

1,ASP,321
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 321
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,321

1,GLU,322
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 322
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,322

1,TYR,323
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 323
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,323

1,LEU,324
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 324
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,324

1,ILE,325
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 325
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,325

1,PRO,326
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 326
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,326

1,GLN,327
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 327
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,327

1,GLN,328
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 328
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,328

1,GLY,329
type: entity poly seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/5HG8/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 329
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,329

1,1
type: entity src gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/1
entity src gen.entity id: 1
entity src gen.pdbx src id: 1
entity src gen.gene src common name: Human
entity src gen.pdbx alt source flag: sample
entity src gen.pdbx beg seq num: 1
entity src gen.pdbx end seq num: 329
entity src gen.pdbx gene src gene: EGFR, ERBB, ERBB1, HER1
entity src gen.pdbx gene src ncbi taxonomy id: 9606
entity src gen.pdbx gene src scientific name: Homo sapiens
entity src gen.pdbx host org ncbi taxonomy id: 7108
entity src gen.pdbx host org scientific name: Spodoptera frugiperda
entity src gen.pdbx seq type: Biological sequence
link to taxonomy source: taxonomy:9606
link to taxonomy host: taxonomy:7108

taxonomy:9606

taxonomy:7108

5HG8,X-RAY DIFFRACTION
type: exptl
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
exptl.entry id: 5HG8
exptl.method: X-RAY DIFFRACTION
exptl.crystals number: 1

http://rdf.wwpdb.org/pdb/5HG8/exptl_crystal_grow/1
type: exptl crystal grow
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to exptl crystal: http://rdf.wwpdb.org/pdb/5HG8/exptl_crystal/1
exptl crystal grow.crystal id: 1
exptl crystal grow.method: VAPOR DIFFUSION, SITTING DROP
exptl crystal grow.pdbx details: 0.1 M (5.0 uL of stock 1.0 M) HEPES (pH 7.50), 0.2 M (2.8571428571 uL of stock 3.5 M) Ammonium sulfate, 20.0 %w/v (20.0 uL of stock 50.0 %w/v) PEG 8000, 10.0 %v/v (5.0 uL of stock 100.0 %v/v) iso-propanol
exptl crystal grow.temp: 286

Structure model,1,4
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 1
pdbx audit revision category.revision ordinal: 4
pdbx audit revision category.category: citation

Structure model,4
referenced by pdbx audit revision category: Structure model,1,4
referenced by pdbx audit revision category: Structure model,2,4
referenced by pdbx audit revision category: Structure model,3,4
referenced by pdbx audit revision group: Structure model,3,4
referenced by pdbx audit revision group: Structure model,4,4
referenced by pdbx audit revision group: Structure model,5,4
type: pdbx audit revision history
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 4
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 3
pdbx audit revision history.revision date: 2017-11-22
referenced by pdbx audit revision item: Structure model,3,4
referenced by pdbx audit revision item: Structure model,1,4
referenced by pdbx audit revision item: Structure model,2,4

Structure model,2,4
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 2
pdbx audit revision category.revision ordinal: 4
pdbx audit revision category.category: pdbx_struct_oper_list

Structure model,3,4
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 3
pdbx audit revision category.revision ordinal: 4
pdbx audit revision category.category: software

Structure model,4,5
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 4
pdbx audit revision category.revision ordinal: 5
pdbx audit revision category.category: chem_comp_atom

Structure model,5
referenced by pdbx audit revision category: Structure model,4,5
referenced by pdbx audit revision category: Structure model,5,5
referenced by pdbx audit revision category: Structure model,6,5
referenced by pdbx audit revision category: Structure model,7,5
referenced by pdbx audit revision group: Structure model,6,5
referenced by pdbx audit revision group: Structure model,7,5
referenced by pdbx audit revision group: Structure model,8,5
type: pdbx audit revision history
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 5
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 4
pdbx audit revision history.revision date: 2024-03-06
referenced by pdbx audit revision item: Structure model,6,5
referenced by pdbx audit revision item: Structure model,4,5
referenced by pdbx audit revision item: Structure model,5,5

Structure model,5,5
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 5
pdbx audit revision category.revision ordinal: 5
pdbx audit revision category.category: chem_comp_bond

Structure model,6,5
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 6
pdbx audit revision category.revision ordinal: 5
pdbx audit revision category.category: database_2

Structure model,7,5
type: pdbx audit revision category
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 7
pdbx audit revision category.revision ordinal: 5
pdbx audit revision category.category: software

Structure model,1,1
type: pdbx audit revision details
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,1
pdbx audit revision details.data content type: Structure model
pdbx audit revision details.ordinal: 1
pdbx audit revision details.revision ordinal: 1
pdbx audit revision details.provider: repository
pdbx audit revision details.type: Initial release

Structure model,1
referenced by pdbx audit revision details: Structure model,1,1
type: pdbx audit revision history
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 1
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 0
pdbx audit revision history.revision date: 2016-02-03

Structure model,1,2
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,2
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 1
pdbx audit revision group.revision ordinal: 2
pdbx audit revision group.group: Database references

Structure model,2
referenced by pdbx audit revision group: Structure model,1,2
type: pdbx audit revision history
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 2
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 1
pdbx audit revision history.revision date: 2016-02-10

Structure model,2,3
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 2
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Database references

Structure model,3
referenced by pdbx audit revision group: Structure model,2,3
type: pdbx audit revision history
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 3
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 2
pdbx audit revision history.revision date: 2016-03-23

Structure model,3,4
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 3
pdbx audit revision group.revision ordinal: 4
pdbx audit revision group.group: Database references

Structure model,4,4
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 4
pdbx audit revision group.revision ordinal: 4
pdbx audit revision group.group: Derived calculations

Structure model,5,4
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 5
pdbx audit revision group.revision ordinal: 4
pdbx audit revision group.group: Refinement description

Structure model,6,5
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 6
pdbx audit revision group.revision ordinal: 5
pdbx audit revision group.group: Data collection

Structure model,7,5
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 7
pdbx audit revision group.revision ordinal: 5
pdbx audit revision group.group: Database references

Structure model,8,5
type: pdbx audit revision group
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 8
pdbx audit revision group.revision ordinal: 5
pdbx audit revision group.group: Refinement description

Structure model,1,4
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 1
pdbx audit revision item.revision ordinal: 4
pdbx audit revision item.item: _citation.journal_id_CSD

Structure model,2,4
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 2
pdbx audit revision item.revision ordinal: 4
pdbx audit revision item.item: _pdbx_struct_oper_list.symmetry_operation

Structure model,3,4
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,4
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 3
pdbx audit revision item.revision ordinal: 4
pdbx audit revision item.item: _software.classification

Structure model,4,5
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 4
pdbx audit revision item.revision ordinal: 5
pdbx audit revision item.item: _database_2.pdbx_DOI

Structure model,5,5
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 5
pdbx audit revision item.revision ordinal: 5
pdbx audit revision item.item: _database_2.pdbx_database_accession

Structure model,6,5
type: pdbx audit revision item
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx audit revision history: Structure model,5
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 6
pdbx audit revision item.revision ordinal: 5
pdbx audit revision item.item: _software.name

unspecified,5HG7,PDB
type: pdbx database related
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx database related.content type: unspecified
pdbx database related.db id: 5HG7
pdbx database related.db name: PDB

unspecified,5HG5,PDB
type: pdbx database related
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx database related.content type: unspecified
pdbx database related.db id: 5HG5
pdbx database related.db name: PDB

unspecified,5HG9,PDB
type: pdbx database related
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx database related.content type: unspecified
pdbx database related.db id: 5HG9
pdbx database related.db name: PDB

5HG8
type: pdbx database status
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
pdbx database status.entry id: 5HG8
pdbx database status.sg entry: N
pdbx database status.deposit site: RCSB
pdbx database status.pdb format compatible: Y
pdbx database status.process site: RCSB
pdbx database status.recvd initial deposition date: 2016-01-08
pdbx database status.status code: REL
pdbx database status.status code sf: REL

http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/2
type: pdbx entity nonpoly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/2
pdbx entity nonpoly.entity id: 2
pdbx entity nonpoly.comp id: 634
pdbx entity nonpoly.name: N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide

http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/3
type: pdbx entity nonpoly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/3
pdbx entity nonpoly.entity id: 3
pdbx entity nonpoly.comp id: SO4
pdbx entity nonpoly.name: SULFATE ION

http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/4
type: pdbx entity nonpoly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/4
pdbx entity nonpoly.entity id: 4
pdbx entity nonpoly.comp id: GOL
pdbx entity nonpoly.name: GLYCEROL

http://rdf.wwpdb.org/pdb/5HG8/pdbx_entity_nonpoly/5
type: pdbx entity nonpoly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/5
pdbx entity nonpoly.entity id: 5
pdbx entity nonpoly.comp id: HOH
pdbx entity nonpoly.name: water

5HG8
type: pdbx entry details
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
pdbx entry details.entry id: 5HG8
pdbx entry details.nonpolymer details: The 634 ligand represent bound form of N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide which has a double bond between C20 and C21 atom group.

B,1
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: B
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: LIG
pdbx nonpoly scheme.auth seq num: 9001
pdbx nonpoly scheme.entity id: 2
pdbx nonpoly scheme.mon id: 634
pdbx nonpoly scheme.pdb mon id: 634
pdbx nonpoly scheme.pdb seq num: 9001
pdbx nonpoly scheme.pdb strand id: A

C,1
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: SO4
pdbx nonpoly scheme.auth seq num: 9002
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: SO4
pdbx nonpoly scheme.pdb mon id: SO4
pdbx nonpoly scheme.pdb seq num: 9002
pdbx nonpoly scheme.pdb strand id: A

D,1
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: D
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: SO4
pdbx nonpoly scheme.auth seq num: 9003
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: SO4
pdbx nonpoly scheme.pdb mon id: SO4
pdbx nonpoly scheme.pdb seq num: 9003
pdbx nonpoly scheme.pdb strand id: A

E,1
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: E
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: GOL
pdbx nonpoly scheme.auth seq num: 9004
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: GOL
pdbx nonpoly scheme.pdb mon id: GOL
pdbx nonpoly scheme.pdb seq num: 9004
pdbx nonpoly scheme.pdb strand id: A

F,1
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 164
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9101
pdbx nonpoly scheme.pdb strand id: A

F,2
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 126
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9102
pdbx nonpoly scheme.pdb strand id: A

F,3
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 156
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9103
pdbx nonpoly scheme.pdb strand id: A

F,4
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 70
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9104
pdbx nonpoly scheme.pdb strand id: A

F,5
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 92
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9105
pdbx nonpoly scheme.pdb strand id: A

F,6
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 149
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9106
pdbx nonpoly scheme.pdb strand id: A

F,7
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 37
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9107
pdbx nonpoly scheme.pdb strand id: A

F,8
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 85
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9108
pdbx nonpoly scheme.pdb strand id: A

F,9
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 28
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9109
pdbx nonpoly scheme.pdb strand id: A

F,10
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 44
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9110
pdbx nonpoly scheme.pdb strand id: A

F,11
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 30
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9111
pdbx nonpoly scheme.pdb strand id: A

F,12
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 188
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9112
pdbx nonpoly scheme.pdb strand id: A

F,13
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 32
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9113
pdbx nonpoly scheme.pdb strand id: A

F,14
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 48
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9114
pdbx nonpoly scheme.pdb strand id: A

F,15
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 23
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9115
pdbx nonpoly scheme.pdb strand id: A

F,16
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 118
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9116
pdbx nonpoly scheme.pdb strand id: A

F,17
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 2
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9117
pdbx nonpoly scheme.pdb strand id: A

F,18
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 83
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9118
pdbx nonpoly scheme.pdb strand id: A

F,19
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 69
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9119
pdbx nonpoly scheme.pdb strand id: A

F,20
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 134
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9120
pdbx nonpoly scheme.pdb strand id: A

F,21
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 111
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9121
pdbx nonpoly scheme.pdb strand id: A

F,22
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 5
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9122
pdbx nonpoly scheme.pdb strand id: A

F,23
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 72
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9123
pdbx nonpoly scheme.pdb strand id: A

F,24
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 42
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9124
pdbx nonpoly scheme.pdb strand id: A

F,25
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 170
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9125
pdbx nonpoly scheme.pdb strand id: A

F,26
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 54
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9126
pdbx nonpoly scheme.pdb strand id: A

F,27
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 201
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9127
pdbx nonpoly scheme.pdb strand id: A

F,28
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 182
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9128
pdbx nonpoly scheme.pdb strand id: A

F,29
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 47
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9129
pdbx nonpoly scheme.pdb strand id: A

F,30
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 1
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9130
pdbx nonpoly scheme.pdb strand id: A

F,31
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 120
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9131
pdbx nonpoly scheme.pdb strand id: A

F,32
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 58
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9132
pdbx nonpoly scheme.pdb strand id: A

F,33
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 194
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9133
pdbx nonpoly scheme.pdb strand id: A

F,34
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 84
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9134
pdbx nonpoly scheme.pdb strand id: A

F,35
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 20
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9135
pdbx nonpoly scheme.pdb strand id: A

F,36
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 197
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9136
pdbx nonpoly scheme.pdb strand id: A

F,37
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 59
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9137
pdbx nonpoly scheme.pdb strand id: A

F,38
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 110
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9138
pdbx nonpoly scheme.pdb strand id: A

F,39
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 204
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9139
pdbx nonpoly scheme.pdb strand id: A

F,40
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 96
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9140
pdbx nonpoly scheme.pdb strand id: A

F,41
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 4
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9141
pdbx nonpoly scheme.pdb strand id: A

F,42
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 38
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9142
pdbx nonpoly scheme.pdb strand id: A

F,43
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 205
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9143
pdbx nonpoly scheme.pdb strand id: A

F,44
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 161
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9144
pdbx nonpoly scheme.pdb strand id: A

F,45
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 107
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9145
pdbx nonpoly scheme.pdb strand id: A

F,46
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 14
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9146
pdbx nonpoly scheme.pdb strand id: A

F,47
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 68
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9147
pdbx nonpoly scheme.pdb strand id: A

F,48
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 195
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9148
pdbx nonpoly scheme.pdb strand id: A

F,49
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 132
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9149
pdbx nonpoly scheme.pdb strand id: A

F,50
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 61
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9150
pdbx nonpoly scheme.pdb strand id: A

F,51
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 128
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9151
pdbx nonpoly scheme.pdb strand id: A

F,52
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 8
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9152
pdbx nonpoly scheme.pdb strand id: A

F,53
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 185
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9153
pdbx nonpoly scheme.pdb strand id: A

F,54
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 77
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9154
pdbx nonpoly scheme.pdb strand id: A

F,55
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 26
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9155
pdbx nonpoly scheme.pdb strand id: A

F,56
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 137
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9156
pdbx nonpoly scheme.pdb strand id: A

F,57
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 172
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9157
pdbx nonpoly scheme.pdb strand id: A

F,58
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 147
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9158
pdbx nonpoly scheme.pdb strand id: A

F,59
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 45
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9159
pdbx nonpoly scheme.pdb strand id: A

F,60
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 82
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9160
pdbx nonpoly scheme.pdb strand id: A

F,61
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 180
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9161
pdbx nonpoly scheme.pdb strand id: A

F,62
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 141
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9162
pdbx nonpoly scheme.pdb strand id: A

F,63
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 60
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9163
pdbx nonpoly scheme.pdb strand id: A

F,64
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 6
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9164
pdbx nonpoly scheme.pdb strand id: A

F,65
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 25
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9165
pdbx nonpoly scheme.pdb strand id: A

F,66
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 95
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9166
pdbx nonpoly scheme.pdb strand id: A

F,67
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 145
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9167
pdbx nonpoly scheme.pdb strand id: A

F,68
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 87
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9168
pdbx nonpoly scheme.pdb strand id: A

F,69
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 16
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9169
pdbx nonpoly scheme.pdb strand id: A

F,70
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 79
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9170
pdbx nonpoly scheme.pdb strand id: A

F,71
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 169
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9171
pdbx nonpoly scheme.pdb strand id: A

F,72
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 24
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9172
pdbx nonpoly scheme.pdb strand id: A

F,73
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 46
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9173
pdbx nonpoly scheme.pdb strand id: A

F,74
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 89
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9174
pdbx nonpoly scheme.pdb strand id: A

F,75
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 176
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9175
pdbx nonpoly scheme.pdb strand id: A

F,76
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 198
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9176
pdbx nonpoly scheme.pdb strand id: A

F,77
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 153
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9177
pdbx nonpoly scheme.pdb strand id: A

F,78
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 62
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9178
pdbx nonpoly scheme.pdb strand id: A

F,79
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 10
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9179
pdbx nonpoly scheme.pdb strand id: A

F,80
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 193
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9180
pdbx nonpoly scheme.pdb strand id: A

F,81
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 19
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9181
pdbx nonpoly scheme.pdb strand id: A

F,82
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 17
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9182
pdbx nonpoly scheme.pdb strand id: A

F,83
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 113
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9183
pdbx nonpoly scheme.pdb strand id: A

F,84
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 90
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9184
pdbx nonpoly scheme.pdb strand id: A

F,85
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 63
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9185
pdbx nonpoly scheme.pdb strand id: A

F,86
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 13
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9186
pdbx nonpoly scheme.pdb strand id: A

F,87
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 99
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9187
pdbx nonpoly scheme.pdb strand id: A

F,88
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 11
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9188
pdbx nonpoly scheme.pdb strand id: A

F,89
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 31
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9189
pdbx nonpoly scheme.pdb strand id: A

F,90
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 52
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9190
pdbx nonpoly scheme.pdb strand id: A

F,91
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 7
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9191
pdbx nonpoly scheme.pdb strand id: A

F,92
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 106
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9192
pdbx nonpoly scheme.pdb strand id: A

F,93
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 192
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9193
pdbx nonpoly scheme.pdb strand id: A

F,94
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 81
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9194
pdbx nonpoly scheme.pdb strand id: A

F,95
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 103
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9195
pdbx nonpoly scheme.pdb strand id: A

F,96
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 115
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9196
pdbx nonpoly scheme.pdb strand id: A

F,97
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 35
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9197
pdbx nonpoly scheme.pdb strand id: A

F,98
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 208
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9198
pdbx nonpoly scheme.pdb strand id: A

F,99
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 155
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9199
pdbx nonpoly scheme.pdb strand id: A

F,100
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 200
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9200
pdbx nonpoly scheme.pdb strand id: A

F,101
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 34
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9201
pdbx nonpoly scheme.pdb strand id: A

F,102
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 135
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9202
pdbx nonpoly scheme.pdb strand id: A

F,103
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 184
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9203
pdbx nonpoly scheme.pdb strand id: A

F,104
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 73
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9204
pdbx nonpoly scheme.pdb strand id: A

F,105
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 163
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9205
pdbx nonpoly scheme.pdb strand id: A

F,106
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 116
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9206
pdbx nonpoly scheme.pdb strand id: A

F,107
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 43
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9207
pdbx nonpoly scheme.pdb strand id: A

F,108
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 178
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9208
pdbx nonpoly scheme.pdb strand id: A

F,109
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 114
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9209
pdbx nonpoly scheme.pdb strand id: A

F,110
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 127
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9210
pdbx nonpoly scheme.pdb strand id: A

F,111
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 97
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9211
pdbx nonpoly scheme.pdb strand id: A

F,112
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 175
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9212
pdbx nonpoly scheme.pdb strand id: A

F,113
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 152
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9213
pdbx nonpoly scheme.pdb strand id: A

F,114
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 190
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9214
pdbx nonpoly scheme.pdb strand id: A

F,115
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 41
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9215
pdbx nonpoly scheme.pdb strand id: A

F,116
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 166
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9216
pdbx nonpoly scheme.pdb strand id: A

F,117
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 202
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9217
pdbx nonpoly scheme.pdb strand id: A

F,118
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 136
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9218
pdbx nonpoly scheme.pdb strand id: A

F,119
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 102
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9219
pdbx nonpoly scheme.pdb strand id: A

F,120
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 183
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9220
pdbx nonpoly scheme.pdb strand id: A

F,121
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 78
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9221
pdbx nonpoly scheme.pdb strand id: A

F,122
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 91
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9222
pdbx nonpoly scheme.pdb strand id: A

F,123
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 189
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9223
pdbx nonpoly scheme.pdb strand id: A

F,124
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 124
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 104
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9224
pdbx nonpoly scheme.pdb strand id: A

F,125
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 125
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 130
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9225
pdbx nonpoly scheme.pdb strand id: A

F,126
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 126
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 57
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9226
pdbx nonpoly scheme.pdb strand id: A

F,127
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 127
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 55
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9227
pdbx nonpoly scheme.pdb strand id: A

F,128
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 128
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 50
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9228
pdbx nonpoly scheme.pdb strand id: A

F,129
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 129
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 98
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9229
pdbx nonpoly scheme.pdb strand id: A

F,130
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 130
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 160
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9230
pdbx nonpoly scheme.pdb strand id: A

F,131
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 131
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 207
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9231
pdbx nonpoly scheme.pdb strand id: A

F,132
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 132
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 18
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9232
pdbx nonpoly scheme.pdb strand id: A

F,133
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 133
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 196
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9233
pdbx nonpoly scheme.pdb strand id: A

F,134
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 134
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 142
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9234
pdbx nonpoly scheme.pdb strand id: A

F,135
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 135
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 177
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9235
pdbx nonpoly scheme.pdb strand id: A

F,136
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 136
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 39
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9236
pdbx nonpoly scheme.pdb strand id: A

F,137
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 137
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 131
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9237
pdbx nonpoly scheme.pdb strand id: A

F,138
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 138
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 144
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9238
pdbx nonpoly scheme.pdb strand id: A

F,139
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 139
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 86
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9239
pdbx nonpoly scheme.pdb strand id: A

F,140
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 140
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 9
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9240
pdbx nonpoly scheme.pdb strand id: A

F,141
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 141
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 122
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9241
pdbx nonpoly scheme.pdb strand id: A

F,142
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 142
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 80
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9242
pdbx nonpoly scheme.pdb strand id: A

F,143
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 143
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 93
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9243
pdbx nonpoly scheme.pdb strand id: A

F,144
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 144
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 203
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9244
pdbx nonpoly scheme.pdb strand id: A

F,145
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 145
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 109
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9245
pdbx nonpoly scheme.pdb strand id: A

F,146
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 146
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 100
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9246
pdbx nonpoly scheme.pdb strand id: A

F,147
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 147
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 51
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9247
pdbx nonpoly scheme.pdb strand id: A

F,148
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 148
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 12
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9248
pdbx nonpoly scheme.pdb strand id: A

F,149
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 149
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 151
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9249
pdbx nonpoly scheme.pdb strand id: A

F,150
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 150
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 140
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9250
pdbx nonpoly scheme.pdb strand id: A

F,151
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 151
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 105
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9251
pdbx nonpoly scheme.pdb strand id: A

F,152
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 152
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 3
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9252
pdbx nonpoly scheme.pdb strand id: A

F,153
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 153
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 56
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9253
pdbx nonpoly scheme.pdb strand id: A

F,154
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 154
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 88
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9254
pdbx nonpoly scheme.pdb strand id: A

F,155
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 155
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 76
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9255
pdbx nonpoly scheme.pdb strand id: A

F,156
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 156
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 124
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9256
pdbx nonpoly scheme.pdb strand id: A

F,157
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 157
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 121
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9257
pdbx nonpoly scheme.pdb strand id: A

F,158
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 158
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 27
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9258
pdbx nonpoly scheme.pdb strand id: A

F,159
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 159
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 101
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9259
pdbx nonpoly scheme.pdb strand id: A

F,160
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 160
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 112
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9260
pdbx nonpoly scheme.pdb strand id: A

F,161
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 161
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 117
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9261
pdbx nonpoly scheme.pdb strand id: A

F,162
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 162
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 71
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9262
pdbx nonpoly scheme.pdb strand id: A

F,163
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 163
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 173
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9263
pdbx nonpoly scheme.pdb strand id: A

F,164
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 164
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 15
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9264
pdbx nonpoly scheme.pdb strand id: A

F,165
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 165
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 36
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9265
pdbx nonpoly scheme.pdb strand id: A

F,166
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 166
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 108
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9266
pdbx nonpoly scheme.pdb strand id: A

F,167
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 167
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 168
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9267
pdbx nonpoly scheme.pdb strand id: A

F,168
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 168
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 148
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9268
pdbx nonpoly scheme.pdb strand id: A

F,169
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 169
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 206
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9269
pdbx nonpoly scheme.pdb strand id: A

F,170
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 170
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 29
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9270
pdbx nonpoly scheme.pdb strand id: A

F,171
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 171
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 179
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9271
pdbx nonpoly scheme.pdb strand id: A

F,172
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 172
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 146
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9272
pdbx nonpoly scheme.pdb strand id: A

F,173
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 173
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 49
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9273
pdbx nonpoly scheme.pdb strand id: A

F,174
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 174
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 67
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9274
pdbx nonpoly scheme.pdb strand id: A

F,175
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 175
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 33
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9275
pdbx nonpoly scheme.pdb strand id: A

F,176
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 176
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 125
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9276
pdbx nonpoly scheme.pdb strand id: A

F,177
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 177
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 66
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9277
pdbx nonpoly scheme.pdb strand id: A

F,178
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 178
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 129
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9278
pdbx nonpoly scheme.pdb strand id: A

F,179
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 179
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 133
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9279
pdbx nonpoly scheme.pdb strand id: A

F,180
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 180
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 64
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9280
pdbx nonpoly scheme.pdb strand id: A

F,181
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 181
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 123
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9281
pdbx nonpoly scheme.pdb strand id: A

F,182
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 182
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 138
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9282
pdbx nonpoly scheme.pdb strand id: A

F,183
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 183
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 75
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9283
pdbx nonpoly scheme.pdb strand id: A

F,184
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 184
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 53
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9284
pdbx nonpoly scheme.pdb strand id: A

F,185
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 185
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 139
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9285
pdbx nonpoly scheme.pdb strand id: A

F,186
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 186
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 158
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9286
pdbx nonpoly scheme.pdb strand id: A

F,187
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 187
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 187
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9287
pdbx nonpoly scheme.pdb strand id: A

F,188
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 188
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 74
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9288
pdbx nonpoly scheme.pdb strand id: A

F,189
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 189
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 22
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9289
pdbx nonpoly scheme.pdb strand id: A

F,190
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 190
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 171
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9290
pdbx nonpoly scheme.pdb strand id: A

F,191
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 191
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 40
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9291
pdbx nonpoly scheme.pdb strand id: A

F,192
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 192
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 150
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9292
pdbx nonpoly scheme.pdb strand id: A

F,193
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 193
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 21
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9293
pdbx nonpoly scheme.pdb strand id: A

F,194
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 194
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 165
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9294
pdbx nonpoly scheme.pdb strand id: A

F,195
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 195
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 159
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9295
pdbx nonpoly scheme.pdb strand id: A

F,196
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 196
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 162
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9296
pdbx nonpoly scheme.pdb strand id: A

F,197
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 197
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 209
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9297
pdbx nonpoly scheme.pdb strand id: A

F,198
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 198
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 154
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9298
pdbx nonpoly scheme.pdb strand id: A

F,199
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 199
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 65
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9299
pdbx nonpoly scheme.pdb strand id: A

F,200
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 200
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 199
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9300
pdbx nonpoly scheme.pdb strand id: A

F,201
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 201
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 167
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9301
pdbx nonpoly scheme.pdb strand id: A

F,202
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 202
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 191
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9302
pdbx nonpoly scheme.pdb strand id: A

F,203
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 203
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 181
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9303
pdbx nonpoly scheme.pdb strand id: A

F,204
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 204
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 119
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9304
pdbx nonpoly scheme.pdb strand id: A

F,205
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 205
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 174
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9305
pdbx nonpoly scheme.pdb strand id: A

F,206
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 206
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 157
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9306
pdbx nonpoly scheme.pdb strand id: A

F,207
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 207
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 143
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9307
pdbx nonpoly scheme.pdb strand id: A

F,208
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 208
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 94
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9308
pdbx nonpoly scheme.pdb strand id: A

F,209
type: pdbx nonpoly scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 209
pdbx nonpoly scheme.auth mon id: WAT
pdbx nonpoly scheme.auth seq num: 186
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 9309
pdbx nonpoly scheme.pdb strand id: A

A,1,GLY,1
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,1
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: 694
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
referenced by pdbx poly seq scheme: A,1,GLY,1
referenced by pdbx poly seq scheme: A,1,SER,2
referenced by pdbx poly seq scheme: A,1,GLY,3
referenced by pdbx poly seq scheme: A,1,GLU,4
referenced by pdbx poly seq scheme: A,1,ALA,5
referenced by pdbx poly seq scheme: A,1,PRO,6
referenced by pdbx poly seq scheme: A,1,ASN,7
referenced by pdbx poly seq scheme: A,1,GLN,8
referenced by pdbx poly seq scheme: A,1,ALA,9
referenced by pdbx poly seq scheme: A,1,LEU,10
referenced by pdbx poly seq scheme: A,1,LEU,11
referenced by pdbx poly seq scheme: A,1,ARG,12
referenced by pdbx poly seq scheme: A,1,ILE,13
referenced by pdbx poly seq scheme: A,1,LEU,14
referenced by pdbx poly seq scheme: A,1,LYS,15
referenced by pdbx poly seq scheme: A,1,GLU,16
referenced by pdbx poly seq scheme: A,1,THR,17
referenced by pdbx poly seq scheme: A,1,GLU,18
referenced by pdbx poly seq scheme: A,1,PHE,19
referenced by pdbx poly seq scheme: A,1,LYS,20
referenced by pdbx poly seq scheme: A,1,LYS,21
referenced by pdbx poly seq scheme: A,1,ILE,22
referenced by pdbx poly seq scheme: A,1,LYS,23
referenced by pdbx poly seq scheme: A,1,VAL,24
referenced by pdbx poly seq scheme: A,1,LEU,25
referenced by pdbx poly seq scheme: A,1,GLY,26
referenced by pdbx poly seq scheme: A,1,SER,27
referenced by pdbx poly seq scheme: A,1,GLY,28
referenced by pdbx poly seq scheme: A,1,ALA,29
referenced by pdbx poly seq scheme: A,1,PHE,30
referenced by pdbx poly seq scheme: A,1,GLY,31
referenced by pdbx poly seq scheme: A,1,THR,32
referenced by pdbx poly seq scheme: A,1,VAL,33
referenced by pdbx poly seq scheme: A,1,TYR,34
referenced by pdbx poly seq scheme: A,1,LYS,35
referenced by pdbx poly seq scheme: A,1,GLY,36
referenced by pdbx poly seq scheme: A,1,LEU,37
referenced by pdbx poly seq scheme: A,1,TRP,38
referenced by pdbx poly seq scheme: A,1,ILE,39
referenced by pdbx poly seq scheme: A,1,PRO,40
referenced by pdbx poly seq scheme: A,1,GLU,41
referenced by pdbx poly seq scheme: A,1,GLY,42
referenced by pdbx poly seq scheme: A,1,GLU,43
referenced by pdbx poly seq scheme: A,1,LYS,44
referenced by pdbx poly seq scheme: A,1,VAL,45
referenced by pdbx poly seq scheme: A,1,LYS,46
referenced by pdbx poly seq scheme: A,1,ILE,47
referenced by pdbx poly seq scheme: A,1,PRO,48
referenced by pdbx poly seq scheme: A,1,VAL,49
referenced by pdbx poly seq scheme: A,1,ALA,50
referenced by pdbx poly seq scheme: A,1,ILE,51
referenced by pdbx poly seq scheme: A,1,LYS,52
referenced by pdbx poly seq scheme: A,1,GLU,53
referenced by pdbx poly seq scheme: A,1,LEU,54
referenced by pdbx poly seq scheme: A,1,ARG,55
referenced by pdbx poly seq scheme: A,1,GLU,56
referenced by pdbx poly seq scheme: A,1,ALA,57
referenced by pdbx poly seq scheme: A,1,THR,58
referenced by pdbx poly seq scheme: A,1,SER,59
referenced by pdbx poly seq scheme: A,1,PRO,60
referenced by pdbx poly seq scheme: A,1,LYS,61
referenced by pdbx poly seq scheme: A,1,ALA,62
referenced by pdbx poly seq scheme: A,1,ASN,63
referenced by pdbx poly seq scheme: A,1,LYS,64
referenced by pdbx poly seq scheme: A,1,GLU,65
referenced by pdbx poly seq scheme: A,1,ILE,66
referenced by pdbx poly seq scheme: A,1,LEU,67
referenced by pdbx poly seq scheme: A,1,ASP,68
referenced by pdbx poly seq scheme: A,1,GLU,69
referenced by pdbx poly seq scheme: A,1,ALA,70
referenced by pdbx poly seq scheme: A,1,TYR,71
referenced by pdbx poly seq scheme: A,1,VAL,72
referenced by pdbx poly seq scheme: A,1,MET,73
referenced by pdbx poly seq scheme: A,1,ALA,74
referenced by pdbx poly seq scheme: A,1,SER,75
referenced by pdbx poly seq scheme: A,1,VAL,76
referenced by pdbx poly seq scheme: A,1,ASP,77
referenced by pdbx poly seq scheme: A,1,ASN,78
referenced by pdbx poly seq scheme: A,1,PRO,79
referenced by pdbx poly seq scheme: A,1,HIS,80

A,1,SER,2
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,2
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb seq num: 695
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,3
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,3
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb seq num: 696
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,4
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,4
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb seq num: 697
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,5
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,5
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb seq num: 698
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,6
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,6
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb seq num: 699
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,7
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,7
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 700
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 700
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,8
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,8
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 701
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 701
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,9
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,9
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 702
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 702
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,10
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,10
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 703
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 703
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,11
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,11
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 704
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 704
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,12
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,12
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 705
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 705
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,13
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,13
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 706
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 706
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,14
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,14
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 707
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 707
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,15
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,15
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 708
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 708
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,16
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,16
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 709
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 709
pdbx poly seq scheme.pdb strand id: A

A,1,THR,17
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,17
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 710
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 710
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,18
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,18
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 711
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 711
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,19
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,19
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 712
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 712
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,20
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,20
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 713
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 713
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,21
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,21
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 714
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 714
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,22
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,22
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 715
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 715
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,23
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,23
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 716
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 716
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,24
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,24
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 717
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 717
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,25
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,25
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 718
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 718
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,26
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,26
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 719
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 719
pdbx poly seq scheme.pdb strand id: A

A,1,SER,27
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,27
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 720
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 720
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,28
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,28
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 721
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 721
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,29
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,29
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 722
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 722
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,30
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,30
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 723
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 723
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,31
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,31
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 724
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 724
pdbx poly seq scheme.pdb strand id: A

A,1,THR,32
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,32
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 725
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 725
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,33
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,33
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 726
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 726
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,34
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,34
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 727
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 727
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,35
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,35
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 728
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 728
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,36
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,36
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 729
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 729
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,37
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,37
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 730
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 730
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,38
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,38
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 731
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 731
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,39
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,39
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 732
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 732
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,40
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,40
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 733
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 733
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,41
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,41
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 734
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 734
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,42
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,42
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 735
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 735
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,43
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,43
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 736
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 736
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,44
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,44
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 737
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 737
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,45
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,45
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 738
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 738
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,46
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,46
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 739
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 739
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,47
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,47
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 740
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 740
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,48
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,48
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 741
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 741
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,49
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,49
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 742
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 742
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,50
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,50
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 743
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 743
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,51
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,51
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 744
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 744
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,52
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,52
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 745
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 745
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,53
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,53
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 746
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 746
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,54
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,54
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 747
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 747
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,55
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,55
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 748
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 748
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,56
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,56
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 749
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 749
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,57
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,57
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 750
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 750
pdbx poly seq scheme.pdb strand id: A

A,1,THR,58
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,58
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 751
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 751
pdbx poly seq scheme.pdb strand id: A

A,1,SER,59
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,59
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 752
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 752
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,60
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,60
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 753
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 753
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,61
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,61
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 754
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 754
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,62
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,62
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 755
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 755
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,63
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,63
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 756
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 756
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,64
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,64
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 757
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 757
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,65
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,65
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 758
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 758
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,66
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,66
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 759
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 759
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,67
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,67
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 760
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 760
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,68
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,68
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 761
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 761
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,69
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,69
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 762
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 762
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,70
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,70
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 763
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 763
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,71
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,71
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 764
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 764
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,72
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,72
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 765
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 765
pdbx poly seq scheme.pdb strand id: A

A,1,MET,73
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,73
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 766
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 766
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,74
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,74
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 767
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 767
pdbx poly seq scheme.pdb strand id: A

A,1,SER,75
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,75
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 768
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 768
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,76
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,76
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 769
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 769
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,77
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,77
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 770
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 770
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,78
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,78
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 771
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 771
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,79
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,79
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 772
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 772
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,80
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,80
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 773
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 773
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,81
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,81
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 774
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 774
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,82
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,82
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 775
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 775
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,83
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,83
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 776
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 776
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,84
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,84
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 777
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 777
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,85
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,85
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 778
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 778
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,86
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,86
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 779
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 779
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,87
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,87
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 780
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 780
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,88
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,88
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 781
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 781
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,89
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,89
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 782
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 782
pdbx poly seq scheme.pdb strand id: A

A,1,THR,90
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,90
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 783
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 783
pdbx poly seq scheme.pdb strand id: A

A,1,SER,91
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,91
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 784
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 784
pdbx poly seq scheme.pdb strand id: A

A,1,THR,92
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,92
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 785
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 785
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,93
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,93
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 786
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 786
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,94
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,94
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 787
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 787
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,95
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,95
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 788
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 788
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,96
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,96
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 789
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 789
pdbx poly seq scheme.pdb strand id: A

A,1,MET,97
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,97
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 790
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 790
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,98
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,98
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 791
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 791
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,99
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,99
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 792
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 792
pdbx poly seq scheme.pdb strand id: A

A,1,MET,100
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,100
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 793
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 793
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,101
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,101
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 794
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 794
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,102
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,102
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 795
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 795
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,103
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,103
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 796
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 796
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,104
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,104
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 797
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 797
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,105
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,105
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 798
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 798
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,106
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,106
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 799
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 799
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,107
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,107
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 800
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 800
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,108
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,108
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 801
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 801
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,109
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,109
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 802
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 802
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,110
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,110
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 803
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 803
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,111
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,111
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 804
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 804
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,112
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,112
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 805
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 805
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,113
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,113
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 806
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 806
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,114
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,114
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 807
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 807
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,115
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,115
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 808
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 808
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,116
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,116
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 809
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 809
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,117
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,117
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 810
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 810
pdbx poly seq scheme.pdb strand id: A

A,1,SER,118
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,118
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 811
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 811
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,119
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,119
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 812
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 812
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,120
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,120
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 813
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 813
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,121
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,121
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 814
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 814
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,122
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,122
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 815
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 815
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,123
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,123
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 816
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 816
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,124
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,124
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 817
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 817
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,125
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,125
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 818
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 818
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,126
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,126
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 819
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 819
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,127
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,127
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 820
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 820
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,128
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,128
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 821
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 821
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,129
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,129
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 822
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 822
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,130
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,130
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 823
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 823
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,131
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,131
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 824
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 824
pdbx poly seq scheme.pdb strand id: A

A,1,MET,132
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,132
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 825
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 825
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,133
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,133
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 826
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 826
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,134
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,134
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 827
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 827
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,135
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,135
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 828
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 828
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,136
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,136
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 829
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 829
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,137
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,137
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 830
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 830
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,138
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,138
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 831
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 831
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,139
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,139
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 832
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 832
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,140
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,140
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 833
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 833
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,141
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,141
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 834
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 834
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,142
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,142
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 835
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 835
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,143
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,143
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 836
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 836
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,144
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,144
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 837
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 837
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,145
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,145
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 838
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 838
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,146
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,146
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 839
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 839
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,147
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,147
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 840
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 840
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,148
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,148
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 841
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 841
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,149
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,149
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 842
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 842
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,150
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,150
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 843
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 843
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,151
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,151
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 844
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 844
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,152
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,152
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 845
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 845
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,153
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,153
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 846
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 846
pdbx poly seq scheme.pdb strand id: A

A,1,THR,154
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,154
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 847
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 847
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,155
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,155
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 848
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 848
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,156
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,156
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 849
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 849
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,157
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,157
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 850
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 850
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,158
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,158
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 851
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 851
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,159
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,159
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 852
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 852
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,160
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,160
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 853
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 853
pdbx poly seq scheme.pdb strand id: A

A,1,THR,161
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,161
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 854
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 854
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,162
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,162
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 855
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 855
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,163
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,163
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 856
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 856
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,164
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,164
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 857
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 857
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,165
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,165
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 858
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 858
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,166
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,166
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 859
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 859
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,167
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,167
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 860
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 860
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,168
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,168
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 861
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 861
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,169
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,169
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 862
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 862
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,170
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,170
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 863
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 863
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,171
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,171
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 864
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 864
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,172
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,172
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 865
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 865
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,173
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,173
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 866
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 866
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,174
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,174
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 867
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 867
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,175
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,175
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 868
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 868
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,176
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,176
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 869
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 869
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,177
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,177
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 870
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 870
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,178
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,178
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 871
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 871
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,179
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,179
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 872
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 872
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,180
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,180
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 873
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 873
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,181
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,181
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 874
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 874
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,182
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,182
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 875
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 875
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,183
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,183
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 876
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 876
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,184
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,184
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 877
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 877
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,185
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,185
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 878
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 878
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,186
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,186
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 879
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 879
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,187
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,187
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 880
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 880
pdbx poly seq scheme.pdb strand id: A

A,1,MET,188
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,188
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 881
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 881
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,189
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,189
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 882
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 882
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,190
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,190
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 883
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 883
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,191
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,191
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 884
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 884
pdbx poly seq scheme.pdb strand id: A

A,1,SER,192
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,192
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 885
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 885
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,193
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,193
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 886
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 886
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,194
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,194
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 887
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 887
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,195
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,195
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 888
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 888
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,196
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,196
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 889
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 889
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,197
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,197
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 890
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 890
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,198
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,198
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 891
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 891
pdbx poly seq scheme.pdb strand id: A

A,1,THR,199
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,199
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 892
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 892
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,200
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,200
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 893
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 893
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,201
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,201
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 894
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 894
pdbx poly seq scheme.pdb strand id: A

A,1,SER,202
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,202
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 895
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 895
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,203
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,203
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 896
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 896
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,204
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,204
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 897
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 897
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,205
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,205
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 898
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 898
pdbx poly seq scheme.pdb strand id: A

A,1,SER,206
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,206
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 899
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 899
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,207
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,207
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 900
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 900
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,208
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,208
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 901
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 901
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,209
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,209
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 902
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 902
pdbx poly seq scheme.pdb strand id: A

A,1,THR,210
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,210
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 903
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 903
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,211
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,211
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 904
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 904
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,212
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,212
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 905
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 905
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,213
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,213
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 906
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 906
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,214
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,214
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 907
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 907
pdbx poly seq scheme.pdb strand id: A

A,1,MET,215
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,215
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 908
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 908
pdbx poly seq scheme.pdb strand id: A

A,1,THR,216
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,216
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 909
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 909
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,217
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,217
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 910
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 910
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,218
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,218
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 911
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 911
pdbx poly seq scheme.pdb strand id: A

A,1,SER,219
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,219
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 912
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 912
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,220
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,220
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 913
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 913
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,221
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,221
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 914
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 914
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,222
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,222
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 915
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 915
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,223
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,223
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 916
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 916
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,224
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,224
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 917
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 917
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,225
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,225
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 918
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 918
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,226
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,226
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 919
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 919
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,227
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,227
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 920
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 920
pdbx poly seq scheme.pdb strand id: A

A,1,SER,228
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,228
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 921
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 921
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,229
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,229
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 922
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 922
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,230
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,230
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 923
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 923
pdbx poly seq scheme.pdb strand id: A

A,1,SER,231
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,231
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 924
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 924
pdbx poly seq scheme.pdb strand id: A

A,1,SER,232
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,232
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 925
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 925
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,233
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,233
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 926
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 926
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,234
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,234
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 927
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 927
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,235
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,235
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 928
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 928
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,236
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,236
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 929
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 929
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,237
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,237
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 930
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 930
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,238
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,238
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 931
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 931
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,239
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,239
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 932
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 932
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,240
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,240
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 933
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 933
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,241
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,241
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 934
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 934
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,242
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,242
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 935
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 935
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,243
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,243
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 936
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 936
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,244
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,244
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 937
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 937
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,245
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,245
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 938
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 938
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,246
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,246
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 939
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 939
pdbx poly seq scheme.pdb strand id: A

A,1,THR,247
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,247
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 940
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 940
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,248
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,248
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 941
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 941
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,249
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,249
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 942
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 942
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,250
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,250
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 943
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 943
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,251
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,251
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 944
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 944
pdbx poly seq scheme.pdb strand id: A

A,1,MET,252
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,252
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 945
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 945
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,253
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,253
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 946
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 946
pdbx poly seq scheme.pdb strand id: A

A,1,MET,254
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,254
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 947
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 947
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,255
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,255
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 948
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 948
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,256
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,256
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 949
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 949
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,257
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,CYS,257
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 950
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 950
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,258
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TRP,258
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 951
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 951
pdbx poly seq scheme.pdb strand id: A

A,1,MET,259
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,259
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 952
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 952
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,260
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,260
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 953
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 953
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,261
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,261
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 954
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 954
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,262
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,262
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 955
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 955
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,263
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,263
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 956
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 956
pdbx poly seq scheme.pdb strand id: A

A,1,SER,264
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,264
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 957
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 957
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,265
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,265
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 958
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 958
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,266
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,266
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 959
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 959
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,267
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,267
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 960
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 960
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,268
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,268
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 961
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 961
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,269
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,269
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 962
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 962
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,270
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,270
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 963
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 963
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,271
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,271
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 964
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 964
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,272
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,272
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 965
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 965
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,273
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,273
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 966
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 966
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,274
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,274
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 967
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 967
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,275
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,275
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 968
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 968
pdbx poly seq scheme.pdb strand id: A

A,1,SER,276
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,276
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 969
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 969
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,277
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LYS,277
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 970
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 970
pdbx poly seq scheme.pdb strand id: A

A,1,MET,278
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,278
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 971
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 971
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,279
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,279
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 972
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 972
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,280
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,280
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 973
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 973
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,281
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,281
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 974
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 974
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,282
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,282
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 975
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 975
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,283
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,283
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 976
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 976
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,284
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,284
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 977
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 977
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,285
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,285
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 978
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 978
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,286
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,286
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 979
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 979
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,287
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,287
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 980
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 980
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,288
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,288
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 981
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 981
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,289
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,289
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 982
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 982
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,290
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,290
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 983
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 983
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,291
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,291
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 984
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 984
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,292
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,292
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 985
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 985
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,293
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,293
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 986
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 986
pdbx poly seq scheme.pdb strand id: A

A,1,MET,294
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,294
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 987
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 987
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,295
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,HIS,295
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 988
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 988
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,296
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,296
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 989
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 989
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,297
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,297
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 990
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 990
pdbx poly seq scheme.pdb strand id: A

A,1,SER,298
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,298
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 991
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 991
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,299
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,299
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 992
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 992
pdbx poly seq scheme.pdb strand id: A

A,1,THR,300
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,THR,300
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 993
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 993
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,301
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,301
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 994
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 994
pdbx poly seq scheme.pdb strand id: A

A,1,SER,302
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,SER,302
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 995
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 995
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,303
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASN,303
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 303
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 996
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 303
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 996
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,304
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PHE,304
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 304
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 997
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 304
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 997
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,305
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,305
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 305
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 998
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 305
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 998
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,306
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ARG,306
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 306
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 999
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 306
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 999
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,307
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,307
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 307
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 307
pdbx poly seq scheme.pdb seq num: 1000
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,308
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,308
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 308
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 308
pdbx poly seq scheme.pdb seq num: 1001
pdbx poly seq scheme.pdb strand id: A

A,1,MET,309
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,309
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 309
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 309
pdbx poly seq scheme.pdb seq num: 1002
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,310
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,310
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 310
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 310
pdbx poly seq scheme.pdb seq num: 1003
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,311
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,311
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 311
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 311
pdbx poly seq scheme.pdb seq num: 1004
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,312
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,312
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 312
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 312
pdbx poly seq scheme.pdb seq num: 1005
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,313
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,313
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 313
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 313
pdbx poly seq scheme.pdb seq num: 1006
pdbx poly seq scheme.pdb strand id: A

A,1,MET,314
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,MET,314
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 314
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 314
pdbx poly seq scheme.pdb seq num: 1007
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,315
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,315
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 315
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 315
pdbx poly seq scheme.pdb seq num: 1008
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,316
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,316
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 316
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 316
pdbx poly seq scheme.pdb seq num: 1009
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,317
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,317
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 317
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 317
pdbx poly seq scheme.pdb seq num: 1010
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,318
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,VAL,318
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 318
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 318
pdbx poly seq scheme.pdb seq num: 1011
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,319
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,319
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 319
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 319
pdbx poly seq scheme.pdb seq num: 1012
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,320
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ALA,320
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 320
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 320
pdbx poly seq scheme.pdb seq num: 1013
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,321
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ASP,321
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 321
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 321
pdbx poly seq scheme.pdb seq num: 1014
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,322
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLU,322
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 322
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 322
pdbx poly seq scheme.pdb seq num: 1015
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,323
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,TYR,323
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 323
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 323
pdbx poly seq scheme.pdb seq num: 1016
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,324
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,LEU,324
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 324
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 324
pdbx poly seq scheme.pdb seq num: 1017
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,325
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,ILE,325
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 325
pdbx poly seq scheme.pdb seq num: 1018
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,326
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,PRO,326
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 326
pdbx poly seq scheme.pdb seq num: 1019
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,327
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,327
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 327
pdbx poly seq scheme.pdb seq num: 1020
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,328
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLN,328
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 328
pdbx poly seq scheme.pdb seq num: 1021
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,329
type: pdbx poly seq scheme
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity poly seq: 1,GLY,329
reference to struct asym: http://rdf.wwpdb.org/pdb/5HG8/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 329
pdbx poly seq scheme.pdb seq num: 1022
pdbx poly seq scheme.pdb strand id: A

5HG8,X-RAY DIFFRACTION
type: pdbx refine
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
pdbx refine.entry id: 5HG8
pdbx refine.pdbx refine id: X-RAY DIFFRACTION
pdbx refine.r factor all no cutoff: 0.21
pdbx refine.r factor obs no cutoff: 0.21
pdbx refine.free r error no cutoff: 0.004
pdbx refine.free r factor no cutoff: 0.213
pdbx refine.free r val test set ct no cutoff: 2773
pdbx refine.free r val test set size perc no cutoff: 4.7

http://rdf.wwpdb.org/pdb/5HG8/pdbx_struct_assembly/1
type: pdbx struct assembly
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx struct assembly.id: 1
pdbx struct assembly.details: author_defined_assembly
pdbx struct assembly.oligomeric count: 1
pdbx struct assembly.oligomeric details: monomeric
referenced by pdbx struct assembly gen: 1,A,B,C,D,E,F,1

1,A,B,C,D,E,F,1
type: pdbx struct assembly gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/5HG8/pdbx_struct_assembly/1
pdbx struct assembly gen.assembly id: 1
pdbx struct assembly gen.asym id list: A,B,C,D,E,F
pdbx struct assembly gen.oper expression: 1

http://rdf.wwpdb.org/pdb/5HG8/pdbx_struct_oper_list/1
type: pdbx struct oper list
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx struct oper list.id: 1
pdbx struct oper list.matrix11: 1
pdbx struct oper list.matrix12: 0
pdbx struct oper list.matrix13: 0
pdbx struct oper list.matrix21: 0
pdbx struct oper list.matrix22: 1
pdbx struct oper list.matrix23: 0
pdbx struct oper list.matrix31: 0
pdbx struct oper list.matrix32: 0
pdbx struct oper list.matrix33: 1
pdbx struct oper list.name: 1_555
pdbx struct oper list.symmetry operation: x,y,z
pdbx struct oper list.type: identity operation
pdbx struct oper list.vector1: 0
pdbx struct oper list.vector2: 0
pdbx struct oper list.vector3: 0

1,2,AA1
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ARG
pdbx struct sheet hbond.range 1 auth seq id: 705
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ARG
pdbx struct sheet hbond.range 1 label seq id: 12
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ILE
pdbx struct sheet hbond.range 2 auth seq id: 780
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ILE
pdbx struct sheet hbond.range 2 label seq id: 87

AA1
referenced by pdbx struct sheet hbond: 1,2,AA1
referenced by pdbx struct sheet hbond: 2,3,AA1
referenced by pdbx struct sheet hbond: 3,4,AA1
referenced by pdbx struct sheet hbond: 4,5,AA1
referenced by pdbx struct sheet hbond: 5,6,AA1
type: struct sheet
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct sheet.id: AA1
struct sheet.number strands: 6
referenced by struct sheet order: 5,6,AA1
referenced by struct sheet range: 6,AA1
referenced by struct sheet order: 1,2,AA1
referenced by struct sheet order: 2,3,AA1
referenced by struct sheet order: 3,4,AA1
referenced by struct sheet order: 4,5,AA1
referenced by struct sheet range: 1,AA1
referenced by struct sheet range: 2,AA1
referenced by struct sheet range: 3,AA1
referenced by struct sheet range: 4,AA1
referenced by struct sheet range: 5,AA1

2,3,AA1
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: GLY
pdbx struct sheet hbond.range 1 auth seq id: 779
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: GLY
pdbx struct sheet hbond.range 1 label seq id: 86
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ILE
pdbx struct sheet hbond.range 2 auth seq id: 789
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ILE
pdbx struct sheet hbond.range 2 label seq id: 96

3,4,AA1
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 3
pdbx struct sheet hbond.range id 2: 4
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: MET
pdbx struct sheet hbond.range 1 auth seq id: 790
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: MET
pdbx struct sheet hbond.range 1 label seq id: 97
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: ALA
pdbx struct sheet hbond.range 2 auth seq id: 743
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: ALA
pdbx struct sheet hbond.range 2 label seq id: 50

4,5,AA1
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 4
pdbx struct sheet hbond.range id 2: 5
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: ILE
pdbx struct sheet hbond.range 1 auth seq id: 744
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: ILE
pdbx struct sheet hbond.range 1 label seq id: 51
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: TYR
pdbx struct sheet hbond.range 2 auth seq id: 727
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: TYR
pdbx struct sheet hbond.range 2 label seq id: 34

5,6,AA1
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
pdbx struct sheet hbond.range id 1: 5
pdbx struct sheet hbond.range id 2: 6
pdbx struct sheet hbond.sheet id: AA1
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: VAL
pdbx struct sheet hbond.range 1 auth seq id: 726
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: VAL
pdbx struct sheet hbond.range 1 label seq id: 33
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 718
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 25

1,2,AA2
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA2
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA2
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: VAL
pdbx struct sheet hbond.range 1 auth seq id: 834
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: VAL
pdbx struct sheet hbond.range 1 label seq id: 141
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LYS
pdbx struct sheet hbond.range 2 auth seq id: 860
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LYS
pdbx struct sheet hbond.range 2 label seq id: 167

AA2
referenced by pdbx struct sheet hbond: 1,2,AA2
type: struct sheet
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct sheet.id: AA2
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AA2
referenced by struct sheet range: 2,AA2
referenced by struct sheet range: 1,AA2

1,2,AA3
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA3
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA3
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LEU
pdbx struct sheet hbond.range 1 auth seq id: 844
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LEU
pdbx struct sheet hbond.range 1 label seq id: 151
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LYS
pdbx struct sheet hbond.range 2 auth seq id: 852
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LYS
pdbx struct sheet hbond.range 2 label seq id: 159

AA3
referenced by pdbx struct sheet hbond: 1,2,AA3
type: struct sheet
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct sheet.id: AA3
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AA3
referenced by struct sheet range: 2,AA3
referenced by struct sheet range: 1,AA3

1,2,AA4
type: pdbx struct sheet hbond
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA4
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA4
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: TYR
pdbx struct sheet hbond.range 1 auth seq id: 869
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: TYR
pdbx struct sheet hbond.range 1 label seq id: 176
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: TYR
pdbx struct sheet hbond.range 2 auth seq id: 891
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: TYR
pdbx struct sheet hbond.range 2 label seq id: 198

AA4
referenced by pdbx struct sheet hbond: 1,2,AA4
type: struct sheet
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct sheet.id: AA4
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AA4
referenced by struct sheet range: 2,AA4
referenced by struct sheet range: 1,AA4

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/1
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 1
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 694
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/2
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 2
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 695
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 2
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/3
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 3
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 696
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 3
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/4
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 4
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 697
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 4
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/5
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 5
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 698
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 5
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/6
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
pdbx unobs or zero occ residues.id: 6
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: PRO
pdbx unobs or zero occ residues.auth seq id: 699
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: PRO
pdbx unobs or zero occ residues.label seq id: 6
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/7
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 7
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 1000
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 307
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/8
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 8
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 1001
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 308
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/9
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 9
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 1002
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 309
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/10
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 10
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1003
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 310
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/11
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 11
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 1004
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 311
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/12
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 12
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 1005
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 312
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/13
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 13
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1006
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 313
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/14
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 14
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 1007
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 314
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/15
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 15
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1008
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 315
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/16
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 16
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1009
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 316
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/17
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 17
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 1010
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 317
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/18
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 18
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 1011
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 318
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/19
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 19
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1012
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 319
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/20
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 20
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 1013
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 320
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/21
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 21
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 1014
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 321
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/22
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 22
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 1015
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 322
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/23
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: TYR
pdbx unobs or zero occ residues.id: 23
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: TYR
pdbx unobs or zero occ residues.auth seq id: 1016
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: TYR
pdbx unobs or zero occ residues.label seq id: 323
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/24
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 24
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 1017
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 324
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/25
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: ILE
pdbx unobs or zero occ residues.id: 25
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ILE
pdbx unobs or zero occ residues.auth seq id: 1018
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ILE
pdbx unobs or zero occ residues.label seq id: 325
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/26
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: PRO
pdbx unobs or zero occ residues.id: 26
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: PRO
pdbx unobs or zero occ residues.auth seq id: 1019
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: PRO
pdbx unobs or zero occ residues.label seq id: 326
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/27
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
pdbx unobs or zero occ residues.id: 27
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 1020
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 327
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/28
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLN
pdbx unobs or zero occ residues.id: 28
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 1021
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 328
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_unobs_or_zero_occ_residues/29
type: pdbx unobs or zero occ residues
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 29
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 1022
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 329
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/5HG8/pdbx_validate_torsion/1
type: pdbx validate torsion
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx validate torsion.id: 1
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: THR
pdbx validate torsion.auth seq id: 783
pdbx validate torsion.phi: -130.92
pdbx validate torsion.psi: -124.38

http://rdf.wwpdb.org/pdb/5HG8/pdbx_validate_torsion/2
type: pdbx validate torsion
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx validate torsion.id: 2
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 837
pdbx validate torsion.phi: -149.23
pdbx validate torsion.psi: 38.32

http://rdf.wwpdb.org/pdb/5HG8/pdbx_validate_torsion/3
type: pdbx validate torsion
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx validate torsion.id: 3
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: GLU
pdbx validate torsion.auth seq id: 872
pdbx validate torsion.phi: -105.4
pdbx validate torsion.psi: -165.45

X-RAY DIFFRACTION,1
type: pdbx xplor file
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx xplor file.pdbx refine id: X-RAY DIFFRACTION
pdbx xplor file.serial no: 1
pdbx xplor file.param file: protein_rep-edited.param
pdbx xplor file.topol file: protein-edited.top

X-RAY DIFFRACTION,2
type: pdbx xplor file
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx xplor file.pdbx refine id: X-RAY DIFFRACTION
pdbx xplor file.serial no: 2
pdbx xplor file.param file: ACCELRYS_CNX:libraries/toppar/dna-rna_rep.para
pdbx xplor file.topol file: ACCELRYS_CNX:libraries/toppar/dna-rna.top

X-RAY DIFFRACTION,3
type: pdbx xplor file
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx xplor file.pdbx refine id: X-RAY DIFFRACTION
pdbx xplor file.serial no: 3
pdbx xplor file.param file: ACCELRYS_CNX:libraries/toppar/water_rep.param
pdbx xplor file.topol file: ACCELRYS_CNX:libraries/toppar/water.top

X-RAY DIFFRACTION,4
type: pdbx xplor file
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
pdbx xplor file.pdbx refine id: X-RAY DIFFRACTION
pdbx xplor file.serial no: 4
pdbx xplor file.param file: ACCELRYS_CNX:libraries/toppar/ion.param
pdbx xplor file.topol file: ACCELRYS_CNX:libraries/toppar/ion.top

5HG8,X-RAY DIFFRACTION
type: refine
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
refine.entry id: 5HG8
refine.pdbx refine id: X-RAY DIFFRACTION
refine.b iso mean: 21.2
refine.aniso B11: 8.43
refine.aniso B12: 0
refine.aniso B13: 0
refine.aniso B22: -3.34
refine.aniso B23: 0
refine.aniso B33: -5.1
refine.ls r factor r free: 0.213
refine.ls r factor r free error: 0.004
refine.ls r factor r work: 0.208
refine.ls r factor obs: 0.208
refine.ls d res high: 1.42
refine.ls d res low: 58.99
refine.ls number reflns r free: 2761
refine.ls number reflns all: 58858
refine.ls number reflns obs: 58555
refine.ls percent reflns r free: 4.7
refine.ls percent reflns obs: 98.9
refine.pdbx r free selection details: RANDOM
refine.pdbx data cutoff high abs f: 1173784.01
refine.pdbx data cutoff low abs f: 0
refine.pdbx diffrn id: 1
refine.pdbx isotropic thermal model: RESTRAINED
refine.pdbx ls cross valid method: THROUGHOUT
refine.pdbx ls sigma f: 0
refine.solvent model details: FLAT MODEL
refine.solvent model param bsol: 39.3485
refine.solvent model param ksol: 0.380685

5HG8,X-RAY DIFFRACTION
type: refine analyze
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
refine analyze.entry id: 5HG8
refine analyze.pdbx refine id: X-RAY DIFFRACTION
refine analyze.luzzati coordinate error free: 0.18
refine analyze.luzzati coordinate error obs: 0.17
refine analyze.luzzati d res low obs: 5
refine analyze.luzzati sigma a free: 0.15
refine analyze.luzzati sigma a obs: 0.17

1,X-RAY DIFFRACTION
type: refine hist
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine hist.cycle id: 1
refine hist.pdbx refine id: X-RAY DIFFRACTION
refine hist.d res high: 1.42
refine hist.d res low: 58.99
refine hist.number atoms solvent: 209
refine hist.number atoms total: 2716
refine hist.pdbx number atoms ligand: 16
refine hist.pdbx number atoms nucleic acid: 0
refine hist.pdbx number atoms protein: 2491

X-RAY DIFFRACTION,c bond d
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_bond_d
refine ls restr.dev ideal: 0.004

X-RAY DIFFRACTION,c bond d na
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_bond_d_na

X-RAY DIFFRACTION,c bond d prot
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_bond_d_prot

X-RAY DIFFRACTION,c angle d
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_d

X-RAY DIFFRACTION,c angle d na
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_d_na

X-RAY DIFFRACTION,c angle d prot
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_d_prot

X-RAY DIFFRACTION,c angle deg
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_deg
refine ls restr.dev ideal: 0.8

X-RAY DIFFRACTION,c angle deg na
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_deg_na

X-RAY DIFFRACTION,c angle deg prot
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_angle_deg_prot

X-RAY DIFFRACTION,c dihedral angle d
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_dihedral_angle_d
refine ls restr.dev ideal: 18.8

X-RAY DIFFRACTION,c dihedral angle d na
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_dihedral_angle_d_na

X-RAY DIFFRACTION,c dihedral angle d prot
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_dihedral_angle_d_prot

X-RAY DIFFRACTION,c improper angle d
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_improper_angle_d
refine ls restr.dev ideal: 0.64

X-RAY DIFFRACTION,c improper angle d na
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_improper_angle_d_na

X-RAY DIFFRACTION,c improper angle d prot
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_improper_angle_d_prot

X-RAY DIFFRACTION,c mcbond it
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_mcbond_it
refine ls restr.dev ideal: 1.15
refine ls restr.dev ideal target: 1.5

X-RAY DIFFRACTION,c mcangle it
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_mcangle_it
refine ls restr.dev ideal: 1.78
refine ls restr.dev ideal target: 2

X-RAY DIFFRACTION,c scbond it
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_scbond_it
refine ls restr.dev ideal: 2.07
refine ls restr.dev ideal target: 2

X-RAY DIFFRACTION,c scangle it
type: refine ls restr
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: c_scangle_it
refine ls restr.dev ideal: 3.03
refine ls restr.dev ideal target: 2.5

1.42,X-RAY DIFFRACTION
type: refine ls shell
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
refine ls shell.d res high: 1.42
refine ls shell.pdbx refine id: X-RAY DIFFRACTION
refine ls shell.r factor r free: 0.293
refine ls shell.r factor r free error: 0.015
refine ls shell.r factor r work: 0.294
refine ls shell.d res low: 1.51
refine ls shell.number reflns r free: 385
refine ls shell.number reflns r work: 8710
refine ls shell.pdbx total number of bins used: 6
refine ls shell.percent reflns r free: 4.2
refine ls shell.percent reflns obs: 93.8

http://rdf.wwpdb.org/pdb/5HG8/reflns/1
type: reflns
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
reflns.pdbx ordinal: 1
reflns.b iso wilson estimate: 18
reflns.d resolution high: 1.42
reflns.d resolution low: 58.99
reflns.entry id: 5HG8
reflns.number obs: 58632
reflns.pdbx rsym value: 0.064
reflns.pdbx diffrn id: 1
reflns.pdbx net i over sigma i: 15
reflns.pdbx redundancy: 6.3
reflns.percent possible obs: 100

http://rdf.wwpdb.org/pdb/5HG8/reflns_shell/1
type: reflns shell
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reflns shell.pdbx ordinal: 1
reflns shell.rmerge i obs: 0.49
reflns shell.d res high: 1.42
reflns shell.d res low: 1.5
reflns shell.mean i over sig i obs: 2.9
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 6.4
reflns shell.percent possible all: 100

http://rdf.wwpdb.org/pdb/5HG8/software/1
type: software
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
software.pdbx ordinal: 1
software.classification: refinement
software.name: CNX
software.version: 2005

http://rdf.wwpdb.org/pdb/5HG8/software/2
type: software
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
software.pdbx ordinal: 2
software.classification: data scaling
software.name: SCALA

http://rdf.wwpdb.org/pdb/5HG8/software/3
type: software
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
software.pdbx ordinal: 3
software.classification: data scaling
software.name: autoPROC

5HG8
type: struct
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
struct.entry id: 5HG8
struct.title: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/B
type: struct asym
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/2
struct asym.id: B
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/C
type: struct asym
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/3
struct asym.id: C
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/D
type: struct asym
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/3
struct asym.id: D
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/E
type: struct asym
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/4
struct asym.id: E
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/5HG8/struct_asym/F
type: struct asym
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/5
struct asym.id: F
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

HELX P1
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P1
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 708
struct conf.beg label asym id: A
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 15
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: THR
struct conf.end auth seq id: 710
struct conf.end label asym id: A
struct conf.end label comp id: THR
struct conf.end label seq id: 17
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA1
struct conf.pdbx PDB helix length: 3

HELX P
referenced by struct conf: HELX P1
referenced by struct conf: HELX P2
referenced by struct conf: HELX P3
referenced by struct conf: HELX P4
referenced by struct conf: HELX P5
referenced by struct conf: HELX P6
referenced by struct conf: HELX P7
referenced by struct conf: HELX P8
referenced by struct conf: HELX P9
referenced by struct conf: HELX P10
referenced by struct conf: HELX P11
referenced by struct conf: HELX P12
referenced by struct conf: HELX P13
referenced by struct conf: HELX P14
referenced by struct conf: HELX P15
referenced by struct conf: HELX P16
type: struct conf type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct conf type.id: HELX_P

HELX P2
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P2
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 755
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 62
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: SER
struct conf.end auth seq id: 768
struct conf.end label asym id: A
struct conf.end label comp id: SER
struct conf.end label seq id: 75
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA2
struct conf.pdbx PDB helix length: 14

HELX P3
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P3
struct conf.beg auth asym id: A
struct conf.beg auth comp id: CYS
struct conf.beg auth seq id: 797
struct conf.beg label asym id: A
struct conf.beg label comp id: CYS
struct conf.beg label seq id: 104
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 806
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 113
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA3
struct conf.pdbx PDB helix length: 10

HELX P4
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P4
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 807
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 114
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ILE
struct conf.end auth seq id: 809
struct conf.end label asym id: A
struct conf.end label comp id: ILE
struct conf.end label seq id: 116
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA4
struct conf.pdbx PDB helix length: 3

HELX P5
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P5
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 810
struct conf.beg label asym id: A
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 117
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 831
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 138
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA5
struct conf.pdbx PDB helix length: 22

HELX P6
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P6
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 839
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 146
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 841
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 148
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA6
struct conf.pdbx PDB helix length: 3

HELX P7
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P7
struct conf.beg auth asym id: A
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 877
struct conf.beg label asym id: A
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 184
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: MET
struct conf.end auth seq id: 881
struct conf.end label asym id: A
struct conf.end label comp id: MET
struct conf.end label seq id: 188
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA7
struct conf.pdbx PDB helix length: 5

HELX P8
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P8
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 882
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 189
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 889
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 196
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA8
struct conf.pdbx PDB helix length: 8

HELX P9
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P9
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 892
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 199
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: THR
struct conf.end auth seq id: 909
struct conf.end label asym id: A
struct conf.end label comp id: THR
struct conf.end label seq id: 216
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA9
struct conf.pdbx PDB helix length: 18

HELX P10
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P10
struct conf.beg auth asym id: A
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 919
struct conf.beg label asym id: A
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 226
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: SER
struct conf.end auth seq id: 921
struct conf.end label asym id: A
struct conf.end label comp id: SER
struct conf.end label seq id: 228
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB1
struct conf.pdbx PDB helix length: 3

HELX P11
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P11
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 922
struct conf.beg label asym id: A
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 229
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 930
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 237
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB2
struct conf.pdbx PDB helix length: 9

HELX P12
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P12
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 940
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 247
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: CYS
struct conf.end auth seq id: 950
struct conf.end label asym id: A
struct conf.end label comp id: CYS
struct conf.end label seq id: 257
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB3
struct conf.pdbx PDB helix length: 11

HELX P13
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P13
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 954
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 261
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 958
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 265
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB4
struct conf.pdbx PDB helix length: 5

HELX P14
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P14
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 960
struct conf.beg label asym id: A
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 267
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 973
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 280
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB5
struct conf.pdbx PDB helix length: 14

HELX P15
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P15
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 974
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 281
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 979
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 286
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB6
struct conf.pdbx PDB helix length: 6

HELX P16
type: struct conf
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conf type: HELX P
struct conf.id: HELX_P16
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 983
struct conf.beg label asym id: A
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 290
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: MET
struct conf.end auth seq id: 987
struct conf.end label asym id: A
struct conf.end label comp id: MET
struct conf.end label seq id: 294
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB7
struct conf.pdbx PDB helix length: 5

covale1
type: struct conn
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct conn type: covale
struct conn.id: covale1
struct conn.conn type id: covale
struct conn.pdbx dist value: 1.799
struct conn.pdbx leaving atom flag: none
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: CYS
struct conn.ptnr1 auth seq id: 797
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: SG
struct conn.ptnr1 label comp id: CYS
struct conn.ptnr1 label seq id: 104
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: 634
struct conn.ptnr2 auth seq id: 9001
struct conn.ptnr2 label asym id: B
struct conn.ptnr2 label atom id: C21
struct conn.ptnr2 label comp id: 634
struct conn.ptnr2 symmetry: 1_555

covale
referenced by struct conn: covale1
type: struct conn type
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct conn type.id: covale

5HG8
type: struct keywords
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
struct keywords.entry id: 5HG8
struct keywords.pdbx keywords: TRANSFERASE/TRANSFERASE INHIBITOR
struct keywords.text: EGFR, Kinase, Inhibitor, Lung Cancer, TRANSFERASE-TRANSFERASE INHIBITOR complex

http://rdf.wwpdb.org/pdb/5HG8/struct_ref/1
type: struct ref
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entity: http://rdf.wwpdb.org/pdb/5HG8/entity/1
struct ref.id: 1
struct ref.db code: EGFR_HUMAN
struct ref.db name: UNP
struct ref.entity id: 1
struct ref.pdbx align begin: 695
struct ref.pdbx db accession: P00533
struct ref.pdbx seq one letter code: SGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHV CRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKIT DFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLP QPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDAD EYLIPQQG
link to uniprot: uniprot:P00533
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1

uniprot:P00533

http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1
type: struct ref seq
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct ref: http://rdf.wwpdb.org/pdb/5HG8/struct_ref/1
struct ref seq.align id: 1
struct ref seq.db align beg: 695
struct ref seq.db align end: 1022
struct ref seq.pdbx PDB id code: 5HG8
struct ref seq.pdbx auth seq align beg: 695
struct ref seq.pdbx auth seq align end: 1022
struct ref seq.pdbx db accession: P00533
struct ref seq.pdbx strand id: A
struct ref seq.ref id: 1
struct ref seq.seq align beg: 2
struct ref seq.seq align end: 329
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/4
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/1
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/2
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/3

http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/1
type: struct ref seq dif
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 1
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: 694
struct ref seq dif.pdbx pdb id code: 5HG8
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P00533
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/2
type: struct ref seq dif
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 2
struct ref seq dif.align id: 1
struct ref seq dif.db mon id: THR
struct ref seq dif.details: engineered mutation
struct ref seq dif.mon id: MET
struct ref seq dif.pdbx auth seq num: 790
struct ref seq dif.pdbx pdb id code: 5HG8
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P00533
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.pdbx seq db seq num: 790
struct ref seq dif.seq num: 97

http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/3
type: struct ref seq dif
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 3
struct ref seq dif.align id: 1
struct ref seq dif.db mon id: LEU
struct ref seq dif.details: engineered mutation
struct ref seq dif.mon id: ARG
struct ref seq dif.pdbx auth seq num: 858
struct ref seq dif.pdbx pdb id code: 5HG8
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P00533
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.pdbx seq db seq num: 858
struct ref seq dif.seq num: 165

http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq_dif/4
type: struct ref seq dif
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/5HG8/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 4
struct ref seq dif.align id: 1
struct ref seq dif.db mon id: VAL
struct ref seq dif.details: engineered mutation
struct ref seq dif.mon id: ARG
struct ref seq dif.pdbx auth seq num: 948
struct ref seq dif.pdbx pdb id code: 5HG8
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P00533
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.pdbx seq db seq num: 948
struct ref seq dif.seq num: 255

1,2,AA1
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA1
struct sheet order.sense: parallel

2,3,AA1
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: AA1
struct sheet order.sense: anti-parallel

3,4,AA1
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet order.range id 1: 3
struct sheet order.range id 2: 4
struct sheet order.sheet id: AA1
struct sheet order.sense: anti-parallel

4,5,AA1
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet order.range id 1: 4
struct sheet order.range id 2: 5
struct sheet order.sheet id: AA1
struct sheet order.sense: anti-parallel

5,6,AA1
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet order.range id 1: 5
struct sheet order.range id 2: 6
struct sheet order.sheet id: AA1
struct sheet order.sense: anti-parallel

1,2,AA2
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA2
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA2
struct sheet order.sense: anti-parallel

1,2,AA3
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA3
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA3
struct sheet order.sense: anti-parallel

1,2,AA4
type: struct sheet order
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA4
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA4
struct sheet order.sense: anti-parallel

1,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 1
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ARG
struct sheet range.beg auth seq id: 705
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ARG
struct sheet range.beg label seq id: 12
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ILE
struct sheet range.end auth seq id: 706
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ILE
struct sheet range.end label seq id: 13

2,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 2
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 777
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 84
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 782
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 89

3,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 3
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 786
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 93
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: GLN
struct sheet range.end auth seq id: 791
struct sheet range.end label asym id: A
struct sheet range.end label comp id: GLN
struct sheet range.end label seq id: 98

4,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 4
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ILE
struct sheet range.beg auth seq id: 740
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ILE
struct sheet range.beg label seq id: 47
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 747
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 54

5,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 5
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: GLY
struct sheet range.beg auth seq id: 724
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: GLY
struct sheet range.beg label seq id: 31
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: TRP
struct sheet range.end auth seq id: 731
struct sheet range.end label asym id: A
struct sheet range.end label comp id: TRP
struct sheet range.end label seq id: 38

6,AA1
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA1
struct sheet range.id: 6
struct sheet range.sheet id: AA1
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: PHE
struct sheet range.beg auth seq id: 712
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: PHE
struct sheet range.beg label seq id: 19
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: GLY
struct sheet range.end auth seq id: 721
struct sheet range.end label asym id: A
struct sheet range.end label comp id: GLY
struct sheet range.end label seq id: 28

1,AA2
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA2
struct sheet range.id: 1
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 833
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 140
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: VAL
struct sheet range.end auth seq id: 834
struct sheet range.end label asym id: A
struct sheet range.end label comp id: VAL
struct sheet range.end label seq id: 141

2,AA2
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA2
struct sheet range.id: 2
struct sheet range.sheet id: AA2
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LYS
struct sheet range.beg auth seq id: 860
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LYS
struct sheet range.beg label seq id: 167
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 861
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 168

1,AA3
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA3
struct sheet range.id: 1
struct sheet range.sheet id: AA3
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 843
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 150
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: THR
struct sheet range.end auth seq id: 847
struct sheet range.end label asym id: A
struct sheet range.end label comp id: THR
struct sheet range.end label seq id: 154

2,AA3
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA3
struct sheet range.id: 2
struct sheet range.sheet id: AA3
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: HIS
struct sheet range.beg auth seq id: 850
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: HIS
struct sheet range.beg label seq id: 157
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ILE
struct sheet range.end auth seq id: 853
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ILE
struct sheet range.end label seq id: 160

1,AA4
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA4
struct sheet range.id: 1
struct sheet range.sheet id: AA4
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: TYR
struct sheet range.beg auth seq id: 869
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: TYR
struct sheet range.beg label seq id: 176
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: HIS
struct sheet range.end auth seq id: 870
struct sheet range.end label asym id: A
struct sheet range.end label comp id: HIS
struct sheet range.end label seq id: 177

2,AA4
type: struct sheet range
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct sheet: AA4
struct sheet range.id: 2
struct sheet range.sheet id: AA4
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ILE
struct sheet range.beg auth seq id: 890
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ILE
struct sheet range.beg label seq id: 197
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: TYR
struct sheet range.end auth seq id: 891
struct sheet range.end label asym id: A
struct sheet range.end label comp id: TYR
struct sheet range.end label seq id: 198

AC1
type: struct site
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct site.id: AC1
struct site.details: binding site for residue 634 A 9001
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: 634
struct site.pdbx auth seq id: 9001
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 12
referenced by struct site gen: 12,AC1
referenced by struct site gen: 1,AC1
referenced by struct site gen: 2,AC1
referenced by struct site gen: 3,AC1
referenced by struct site gen: 4,AC1
referenced by struct site gen: 5,AC1
referenced by struct site gen: 6,AC1
referenced by struct site gen: 7,AC1
referenced by struct site gen: 8,AC1
referenced by struct site gen: 9,AC1
referenced by struct site gen: 10,AC1
referenced by struct site gen: 11,AC1

AC2
type: struct site
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct site.id: AC2
struct site.details: binding site for residue SO4 A 9002
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: SO4
struct site.pdbx auth seq id: 9002
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 5
referenced by struct site gen: 17,AC2
referenced by struct site gen: 13,AC2
referenced by struct site gen: 14,AC2
referenced by struct site gen: 15,AC2
referenced by struct site gen: 16,AC2

AC3
type: struct site
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct site.id: AC3
struct site.details: binding site for residue SO4 A 9003
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: SO4
struct site.pdbx auth seq id: 9003
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 3
referenced by struct site gen: 20,AC3
referenced by struct site gen: 18,AC3
referenced by struct site gen: 19,AC3

AC4
type: struct site
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
struct site.id: AC4
struct site.details: binding site for residue GOL A 9004
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: GOL
struct site.pdbx auth seq id: 9004
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 9
referenced by struct site gen: 29,AC4
referenced by struct site gen: 21,AC4
referenced by struct site gen: 22,AC4
referenced by struct site gen: 23,AC4
referenced by struct site gen: 24,AC4
referenced by struct site gen: 25,AC4
referenced by struct site gen: 26,AC4
referenced by struct site gen: 27,AC4
referenced by struct site gen: 28,AC4

1,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 1
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 718
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 25
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

2,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 2
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 743
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 50
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

3,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 3
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 791
struct site gen.label asym id: A
struct site gen.label comp id: GLN
struct site gen.label seq id: 98
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

4,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 4
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: MET
struct site gen.auth seq id: 793
struct site gen.label asym id: A
struct site gen.label comp id: MET
struct site gen.label seq id: 100
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

5,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 5
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: PRO
struct site gen.auth seq id: 794
struct site gen.label asym id: A
struct site gen.label comp id: PRO
struct site gen.label seq id: 101
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

6,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 6
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: GLY
struct site gen.auth seq id: 796
struct site gen.label asym id: A
struct site gen.label comp id: GLY
struct site gen.label seq id: 103
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

7,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 7
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: CYS
struct site gen.auth seq id: 797
struct site gen.label asym id: A
struct site gen.label comp id: CYS
struct site gen.label seq id: 104
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

8,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 8
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ARG
struct site gen.auth seq id: 841
struct site gen.label asym id: A
struct site gen.label comp id: ARG
struct site gen.label seq id: 148
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

9,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 9
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 844
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 151
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

10,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 10
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: TYR
struct site gen.auth seq id: 998
struct site gen.label asym id: A
struct site gen.label comp id: TYR
struct site gen.label seq id: 305
struct site gen.pdbx num res: 12
struct site gen.symmetry: 3_644

11,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 11
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9155
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

12,AC1
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC1
struct site gen.id: 12
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9265
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 12
struct site gen.symmetry: 1_555

13,AC2
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC2
struct site gen.id: 13
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: ARG
struct site gen.auth seq id: 836
struct site gen.label asym id: A
struct site gen.label comp id: ARG
struct site gen.label seq id: 143
struct site gen.pdbx num res: 5
struct site gen.symmetry: 1_555

14,AC2
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC2
struct site gen.id: 14
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: TYR
struct site gen.auth seq id: 869
struct site gen.label asym id: A
struct site gen.label comp id: TYR
struct site gen.label seq id: 176
struct site gen.pdbx num res: 5
struct site gen.symmetry: 1_555

15,AC2
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC2
struct site gen.id: 15
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 871
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 178
struct site gen.pdbx num res: 5
struct site gen.symmetry: 1_555

16,AC2
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC2
struct site gen.id: 16
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: GLU
struct site gen.auth seq id: 872
struct site gen.label asym id: A
struct site gen.label comp id: GLU
struct site gen.label seq id: 179
struct site gen.pdbx num res: 5
struct site gen.symmetry: 1_555

17,AC2
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC2
struct site gen.id: 17
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9149
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 5
struct site gen.symmetry: 1_555

18,AC3
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC3
struct site gen.id: 18
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: ARG
struct site gen.auth seq id: 803
struct site gen.label asym id: A
struct site gen.label comp id: ARG
struct site gen.label seq id: 110
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_555

19,AC3
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC3
struct site gen.id: 19
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 864
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 171
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_655

20,AC3
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC3
struct site gen.id: 20
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 913
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 220
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_555

21,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 21
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: GLU
struct site gen.auth seq id: 709
struct site gen.label asym id: A
struct site gen.label comp id: GLU
struct site gen.label seq id: 16
struct site gen.pdbx num res: 9
struct site gen.symmetry: 2_555

22,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 22
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: THR
struct site gen.auth seq id: 940
struct site gen.label asym id: A
struct site gen.label comp id: THR
struct site gen.label seq id: 247
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

23,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 23
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ILE
struct site gen.auth seq id: 941
struct site gen.label asym id: A
struct site gen.label comp id: ILE
struct site gen.label seq id: 248
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

24,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 24
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ASP
struct site gen.auth seq id: 942
struct site gen.label asym id: A
struct site gen.label comp id: ASP
struct site gen.label seq id: 249
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

25,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 25
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ARG
struct site gen.auth seq id: 977
struct site gen.label asym id: A
struct site gen.label comp id: ARG
struct site gen.label seq id: 284
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

26,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 26
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: TYR
struct site gen.auth seq id: 978
struct site gen.label asym id: A
struct site gen.label comp id: TYR
struct site gen.label seq id: 285
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

27,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 27
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9117
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 9
struct site gen.symmetry: 2_555

28,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 28
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9142
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

29,AC4
type: struct site gen
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to struct site: AC4
struct site gen.id: 29
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 9172
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 9
struct site gen.symmetry: 1_555

5HG8
type: symmetry
of datablock: EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide
reference to entry: 5HG8
symmetry.entry id: 5HG8
symmetry.int tables number: 19
symmetry.space group name H-M: P 21 21 21