Structural analysis of KSHV thymidylate synthase

Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed.

PHEELQYLRQLREILCRGSDRLDRTGIGTLSLFGMQARYSLRDHFPLLTTKRVFWRGVVQELLWFLKGSTDSRELSRTGV
KIWDKNGSREFLAGRGLAHRREGDLGPVYGFQWRHFGAAYVDADADYTGQGFDQLSYIVDLIKNNPHDRRIIMCAWNPAD
LSLMALPPCHLLCQFYVADGELSCQLYQRSGDMGLGVPFNIASYSLLTYMLAHVTGLRPGEFIHTLGDAHIYKTHIEPLR
LQLTRTPRPFPRLEILRSVSSMEEFTPDDFRLVDYCPHPTIRME

potassium phosphate (monobasic), PEG 8K, glycerol

Ministry for Food, Agriculture, Forestry and Fisheries, Korea

thymidylate synthase, inhibitor, raltitrexed, dUMP, TRANSFERASE