JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H4(1-15)R3me2s PEPTIDE

Arginine Demethylation is Catalysed by a Subset of Jmjc Histone Lysine Demethylases.

HISTONE H4(1-15)R3ME2S PEPTIDE, UNP RESIDUES 2-16

JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A, JUMONJI DOMAIN CONTAINING PROTEIN 2A

MHHHHHHSSGVDLGTENLYFQSMASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRAS
YDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNG
TLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKR
LERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIE
YGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESEL

SITTING DROPS, 277 K, 0.15 M POTASSIUM BROMIDE, 30 % W/V PEG 2000 MME, pH 7.5

JMJD2A, OXIDOREDUCTASE, NON-HEME, IRON, 2-OXOGLUTARATE, DIOXYGENASE, OXYGENASE, DOUBLE-STRANDED BETA HELIX, DSBH, FACIAL TRIAD, DEMETHYLASE, HISTONE, JMJC DOMAIN, METAL BINDING PROTEIN, EPIGENETIC AND TRANSCRIPTION REGULATION, CHROMATIN REGULATOR, HYDROXYLATION