De novo structure of the binary mosquito larvicide BinAB at pH 10

De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.

RECEPTOR BINDING COMPONENT OF BINARY TOXIN BINAB

MRNLDFIDSFIPTEGKYIRVMDFYNSEYPFCIHAPSAPNGDIMTEICSRENNQYFIFFPTDDGRVIIANRHNGSVFTGEA
TSVVSDIYTGSPLQFFREVKRTMATYYLAIQNPESATDVRALEPHSHELPSRLYYTNNIENNSNILISNKEQIYLTLPSL
PENEQYPKTPVLSGIDDIGPNQSEKSIIGSTLIPCIMVSDFISLGERMKTTPYYYVKHTQYWQSMWSALFPPGSKETKTE
KSGITDTSQISMTDGINVSIGADFGLRFGNKTFGIKGGFTYDTKTQITNTSQLLIETTYTREYTNTENFPVRYTGYVLAS
EFTLHRSDGTQVNTIPWVALNDNYTTIARYPHFASEPLLGNTKIITDDQN

MCDSKDNSGVSEKCGKKFTNYPLNTTPTSLNYNLPEISKKFYNLKNKYSRNGYGLSKTEFPSSIENCPSNEYSIMYDNKD
PRFLIRFLLDDGRYIIADRDDGEVFDEAPTYLDNNNHPIISRHYTGEERQKFEQVGSGDYITGEQFFQFYTQNKTRVLSN
CRALDSRTILLSTAKIFPIYPPASETQLTAFVNSSFYAAAIPQLPQTSLLENIPEPTSLDDSGVLPKDAVRAVKGSALLP
CIIVHDPNLNNSDKMKFNTYYLLEYKEYWHQLWSQIIPAHQTVKIQERTGISEVVQNSMIEDLNMYIGADFGMLFYFRSS
GFKEQITRGLNRPLSQTTTQLGERVEEMEYYNSNDLDVRYVKYALAREFTLKRVNGEIVKNWVAVDYRLAGIQSYPNAPI
TNPLTLTKHTIIRCENSYDGHIFKTPLIFKNGEVIVKTNEELIPKINQ

BACILLUS THURINGIENSIS SEROVAR ISRAELENSIS

NATURALLY OCCURRING NANOCRYSTALS FORMED IN VIVO, pH 10

DE NOVO STRUCTURE OF THE BINARY MOSQUITO LARVICIDE BINAB AT PH 7

ONLY RESIDUES 5-370 ARE DEFINED IN THE ELECTRON DENSITY ONLY RESIDUES 28-448 ARE DEFINED IN THE ELECTRON DENSITY

TOXIN, BINAB INSECTICIDAL TOXIN, PORE FORMING TOXIN, XFEL, SERIAL FEMTOSECOND CRYSTALLOGRAPHY, DE NOVO MIRAS PHASING, IN VIVO CRYSTALS