HUMANISED MONOMERIC RADA IN COMPLEX WITH FHTG TETRAPEPTIDE

Structure Activity Relationship of the Peptide Binding Motif Mediating the Rad51:Brca2 Protein-Protein Interaction.

DNA repair and recombination protein RadA

ACETYLATED AT THE N-TERMINUS AND AMIDATED IN THE C-TERMINUS

MATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVMWIDTENTFRPERIREIA
QNRGLDPDEVLKHIAYARAFNSNHQMLLVQQAEDMIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLA
DLHRLANLYDIAVFVTNQVQANGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGIED

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

8% PEG-1000, 100 MM NAK PHOSPHATE, PH 6.2

HUMANISED MONOMERIC RADA IN COMPLEX WITH OLIGOMERISATION PEPTIDE

HUMANISED MONOMERIC RADA IN COMPLEX WITH FHTU TETRAPEPTIDE

HUMANISED MONOMERIC RADA IN COMPLEX WITH FHPA TETRAPEPTIDE

HUMANISED MONOMERIC RADA IN COMPLEX WITH WHTA TETRAPEPTIDE

HUMANISED MONOMERIC RADA IN COMPLEX WITH FHAA TETRAPEPTIDE

MUTATIONS I169M, Y201A, V202Y, K221M AND REPLACEMENT OF LOOP 287-300 BY AN N.

HYDROLASE, RADA, FXXA MOTIF, RECOMBINASE

ATIGRISTGSKSLDKLLGGGIETQAITEVFGEFGSGKTQLAHTLAVMVQLPPEEGGLNGSVIWIDTENTFRPERIREIAQ
NRGLDPDEVLKHIYVARAFNSNHQMLLVQQAEDKIKELLNTDRPVKLLIVDSLTSHFRSEYIGRGALAERQQKLAKHLAD
LHRLANLYDIAVFVTNQVQARPDAFFGDPTRPIGGHILAHSATLRVYLRKGKGGKRIARLIDAPHLPEGEAVFSITEKGI
ED

binding site for Di-peptide ACE E 0 and PHE E 1

binding site for Di-peptide GLY E 4 and NH2 E 5

binding site for Di-peptide ACE F 101 and PHE F 103

binding site for Di-peptide GLY F 106 and NH2 F 108