Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group

(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".

TSPO, Translocator protein TspO, TspO regulatory protein, Translocator protein 18 kDa

MNMDWALFLTFLAACGAPATTGALLKPDEWYDNLNKPWWNPPRWVFPLAWTSLYFLMSLAAMRVAQLEGSGQALAFYAAQ
LAFNTLWTPVFFGMKRMATALAVVMVMWLFVAATMWAFFQLDTWAGVLFVPYLIWATATTGLNFEAMRLNWNRPEAR

31% v/v pentaerythritol ethoxylate 15/04, 100 mM Tris, pH 7.0, 200 mM ammonium acetate

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Translocator protein TspO with the same ligands, 1.80 Angstrom resolution

Protoporphyrin IX was used as a representative of a porphyrin compound and was the best interpretation of the extra density based on spectral data that showed what appeared to be an oxidized porphyrin.

mitochondria, transport, 5 transmembrane helices, MEMBRANE PROTEIN

MNMDWALFLTFLAACGAPATTGALLKPDEWYDNLNKPWWNPPRWVFPLAWTSLYFLMSLAAMRVAQLEGSGQALAFYAAQ
LAFNTLWTPVFFGMKRMATALAVVMVMWLFVAATMWAFFQLDTWAGVLFVPYLIWATAATGLNFEAMRLNWNRPEAR