monomeric PCNA bound to a small protein inhibitor

A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.

DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen

Proliferating cell nuclear antigen homolog 1,PCNA 1

MPFEVVFDGAKEFADLIATASNLIDEAAFKFTEEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDQFKKIL
KRGKAKDTLILRKGDENFLEITFEGTAKRTFRLPLIDVEELELELPELPFTAKVVLLGEVLKEGIKDASLVSDAIKFIAK
ENEFTMKAEGETNEVEIRLTLEDEGLLDLEVEEETKSAYGIRYLSDMVKGIGKADEVILRFGNEMPLQMEYMIRDEGRLT
FLLAPRVEEHHHHHH

Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

Well solution: 1.2 M ammonium sulfate, 50 mM sodium citrate buffer, and 10% glycerol

3LX1 is the same protein without the bound inhibitor protein

complex, inhibitor, DNA binding protein-inhibitor complex

MPFEVVFDGAKEFADLIATASNLIDEAAFKFTEEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEPETIGINMDQFKKIL
KRGKAKDTLILRKGDENFLEITFEGTAKRTFRLPLIDVEELELELPELPFTAKVVLLGEVLKEGIKDASLVSDAIKFIAK
ENEFTMKAEGETNEVEIRLTLEDEGLLDLEVEEETKSAYGIRYLSDMVKGIGKADEVILRFGNEMPLQMEYMIRDEGRLT
FLLAPRVEE