C. remanei PGL-1 Dimerization Domain - Hg

PGL germ granule assembly protein is a base-specific, single-stranded RNase.

GKLLLEGVKEQDPVDKFTYLLLQPLTEATLSDAVNFIVEKYSAELPDEGDASLVVRSQLGCQFFFLVTRTLAHDQRELAK
LVQTLIPRPVRLEVFPGLQRSVFKSSVFLGHHIIQIFMGAKKPFQDWSFVGLAQDFECPWRRLAIAELLKKFSVSVVEKV
FDNPVALIPQHESDNEALIELVTNALRFALWIVEFYETETNEKSIKELAFLDHSSKTLLIESFTKFLQGKDVKDQDHLKR
IIDALEKS

codon optimized for E.coli, ordered synthetic

100 mM PIPES pH 6.0, 24-27% PEG 4K, 200 mM LiSO4

National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)

5COW a higher resolution structure built from this initial, phased model

guanosine endonuclease, P-granule, dimer, HYDROLASE

KLLLEGVKEQDPVDKFTYLLLQPLTEATLSDAVNFIVEKYSAELPDEGDASLVVRSQLGCQFFFLVTRTLAHDQRELAKL
VQTLIPRPVRLEVFPGLQRSVFKSSVFLGHHIIQIFMGCEFCSIQSIKNTMFSAKKPFQDWSFVGLAQDFECPWRRLAIA
ELLKKFSVSVVEKVFDNPVALIPQHESDNEALIELVTNALRFALWIVEFYETETNEKSIKELAFLDHSSKTLLIESFTKF
LQGKDVKDQDHLKRIIDALEKS