DAHP synthase from Mycobacterium tuberculosis, fully inhibited by tyrosine, phenylalanine, and tryptophan

Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway.

Phospho-2-dehydro-3-deoxyheptonate aldolase AroG

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase,DAHP synthase,Phospho-2-keto-3-deoxyheptonate aldolase

MHHHHHHSSGMNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQ
LAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGD
MINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSA
CGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPN
MTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDE
VQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD

ammonium sulfate, glycerol, magnesium chloride, TCEP

3NV8 contains the same protein complexed with phosphoenolpyruvate, no amino acids bound

2B7O contains the same protein, thesit free, no amino acids bound

3KGF contains the same protein with phenylalanine and tryptophan bound

3NUD contains the same protein with phenylalanine, also in tryptophan binding sites

3NUE contains the same protein with tryptophan in the tryptophan binding sites

3RZI contains the same protein co-crystallized with phenylalanine and tryptophan bound

2YPP contains the same protein complexed with 3 tyrosine molecules

2YPO contains the same protein with phenylalanine only in one site

2YPQ contains the same protein with tyrosine and tryptophan bound

TIM-barrel, shikimate pathway, feedback inhibition, transferase

MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAF
LLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAA
AREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQT
AEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYV
ERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRA
LGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD