Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 7
Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP.
Baculoviral IAP repeat-containing protein 4,IAP-like protein,hILP,Inhibitor of apoptosis protein 3,hIAP3,X-linked inhibitor of apoptosis protein,X-linked IAP
GSHMNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWY PGCKYLLEQKGQEYINNIHLTHSLEECLVR
HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT
E3 ubiquitin-protein ligase XIAP (E.C.6.3.2.-)
NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCK YLLEQKGQEYINNIHLTHSLEECLVR