Molecular insights into the specificity of exfoliative toxins from Staphylococcus aureus

Crystal structure of Staphylococcus aureus exfoliative toxin D-like protein: Structural basis for the high specificity of exfoliative toxins.

HHHHHHMIEYTDEEIQKKRDFFKTRPSDSELFSKIQDTTRSPYSSVGTVFVKGKTIATGILIGKNTVITNKHIARLAEND
PNKVIFTPGSTRDEGSLVVKKPFGEFIAEEINEAPYGGGTDLSIIKLKPNQYGKSAGDLVTPAAIPDNVDVQKGDKISLL
GYPYNTSTHSLYKSQIEVFNNQTFQYFAYTEPGNSGSGIFNLHGELVGIHSGKGGQYGLPFGILFNRQIGSSYSTDKTVT
TLAIDLKNKAKTQEQ

Monomer confirmed by analytical ultracentrifugation

esfoliative toxin, Staphylococcus aureus, ETD, TOXIN

IEYTDEEIQKKRDFFKTRPSDSELFSKIQDTTRSPYSSVGTVFVKGKTIATGILIGKNTVITNKHIARLAENDPNKVIFT
PGSTRDEGSLVVKKPFGEFIAEEINEAPYGGGTDLSIIKLKPNQYGKSAGDLVTPAAIPDNVDVQKGDKISLLGYPYNTS
THSLYKSQIEVFNNQTFQYFAYTEPGNSGSGIFNLHGELVGIHSGKGGQYGLPFGILFNRQIGSSYSTDKTVTTLAIDLK
NKAKTQEQ