Structure of Leishmania major peroxidase D211N mutant

"Bind and Crawl" Association Mechanism of Leishmania Major Peroxidase and Cytochrome C Revealed by Brownian and Molecular Dynamics Simulations.

C-TERMINAL CATALYTIC DOMAIN, RESIDUES 35-303

SEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKK
KYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHT
CGECHIEFSGYHGPWTHNKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDN
DRFNKDFANAFKKLTELGTRNLHKAPASES

10% PEG MME 5000, 0.1M MES:NAOH PH 6.5, 7.5 MM PRASEODYMIUM(III) ACETATE HYDRATE

STRUCTURE OF LEISHMANIA MAJOR PEROXIDASE D211R MUTANT ( HIGH RES)

STRUCTURE OF LEISHMANIA MAJOR PEROXIDASE D211R MUTANT ( LOW RES)

THE PROTEIN EXPRESSED IS DELTA34LMP, WHICH HAD THE FIRST 34 RESIDUES REMOVED.

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES WITH TLS ADDED RESIDUES 301-303 ARE DISORDERED IN BOTH CHAINS.