Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash II structure

Structural Dynamics of the Cereblon Ligand Binding Domain.

AMPLDAGGQNSTQMVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSW
FKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPAD

100 MM TRI-SODIUM CITRATE PH 5.6, 1.0 M AMMONIUM PHOSPHATE

CEREBLON ISOFORM 4 FROM MAGNETOSPIRILLUM GRYPHISWALDENSE IN COMPLEX WITH THALIDOMIDE, TRIGONAL CRYSTAL FORM

CEREBLON ISOFORM 4 FROM MAGNETOSPIRILLUM GRYPHISWALDENSE IN COMPLEX WITH THALIDOMIDE, WASH I STRUCTURE

CEREBLON ISOFORM 4 FROM MAGNETOSPIRILLUM GRYPHISWALDENSE IN MULTIPLE CONFORMATIONS, HEXAGONAL CRYSTAL FORM

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES WITH TLS ADDED

SIGNALING PROTEIN, TERATOGENICITY, AROMATIC CAGE