JC Polyomavirus VP1 five-fold pore mutant N221Q

Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins.

GSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCG
NILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQ
SQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGEQVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVD
VCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

beta-sandwich, jelly-roll, viral major capsid protein, five-fold pore, viral protein

GGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILM
WEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVM
NTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGM
FTNRSGSQQWRGLSRYFKVQLRKRRVKN