X-ray structure of the dimeric CCL2 lectin in native form

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

MGHHHHHHHHSGDSPAVTLSAGNYIIYNRVLSPRGEKLALTYPGRQRTPVTVSPLDGSSEQAWILRSYDSNSNTWTISPV
GSPNSQIGWGAGNVPVVLPPNNYVWTLTLTSGGYNIQDGKRTVSWSLNNATAGEEVSIGADATFSGRWVIEKV

MIDAS 1-14 15% PENTAERYTHRITOL PROPOXYLATE 5/4 PO/OH 0.1M HEPES 7.50 0.2M SODIUM THIOCYANATE

X-RAY STRUCTURE OF THE CCL2 LECTIN IN COMPLEX WITH SIALYL LEWIS X

CRYSTAL STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA7 IN COMPLEX WITH LEWIS A TETRASACCHARIDE

SHEET
DETERMINATION METHOD: DSSP
THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS
BELOW IS ACTUALLY AN 6-STRANDED BARREL THIS IS REPRESENTED BY
A 7-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS
ARE IDENTICAL.

THE SHEETS PRESENTED AS "BA" IN EACH CHAIN ON SHEET RECORDS
BELOW IS ACTUALLY AN 6-STRANDED BARREL THIS IS REPRESENTED BY
A 7-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS
ARE IDENTICAL.

THE FIRST 12 AMINO ACIDS ARE FROM THE NTERMINAL HISTAG

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES WITH TLS ADDED DISORDERED REGIONS WERE MODELED STEREOCHEMICALLY