N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
type: datablock
alternative label: 4UIY
link to mmcif: 4UIY.cif.gz
link to pdbml: 4UIY.xml.gz
link to pdbml noatom: 4UIY-noatom.xml.gz
link to pdbml extatom: 4UIY-extatom.xml.gz
link to doi: doi:10.2210/pdb4UIY/pdb
datablock name: 4UIY-noatom
has atom sites category: atom sitesCategory
has atom type category: atom typeCategory
has audit author category: audit authorCategory
has audit conform category: audit conformCategory
has cell category: cellCategory
has chem comp category: chem compCategory
has citation category: citationCategory
has citation author category: citation authorCategory
has database 2 category: database 2Category
has database PDB matrix category: database PDB matrixCategory
has diffrn category: diffrnCategory
has diffrn detector category: diffrn detectorCategory
has diffrn radiation category: diffrn radiationCategory
has diffrn radiation wavelength category: diffrn radiation wavelengthCategory
has diffrn source category: diffrn sourceCategory
has entity category: entityCategory
has entity name com category: entity name comCategory
has entity poly category: entity polyCategory
has entity poly seq category: entity poly seqCategory
has entity src gen category: entity src genCategory
has entry category: entryCategory
has exptl category: exptlCategory
has exptl crystal category: exptl crystalCategory
has exptl crystal grow category: exptl crystal growCategory
has pdbx audit revision category category: pdbx audit revision categoryCategory
has pdbx audit revision details category: pdbx audit revision detailsCategory
has pdbx audit revision group category: pdbx audit revision groupCategory
has pdbx audit revision history category: pdbx audit revision historyCategory
has pdbx audit revision item category: pdbx audit revision itemCategory
has pdbx database related category: pdbx database relatedCategory
has pdbx database status category: pdbx database statusCategory
has pdbx distant solvent atoms category: pdbx distant solvent atomsCategory
has pdbx entity nonpoly category: pdbx entity nonpolyCategory
has pdbx nonpoly scheme category: pdbx nonpoly schemeCategory
has pdbx poly seq scheme category: pdbx poly seq schemeCategory
has pdbx refine tls category: pdbx refine tlsCategory
has pdbx refine tls group category: pdbx refine tls groupCategory
has pdbx struct assembly category: pdbx struct assemblyCategory
has pdbx struct assembly gen category: pdbx struct assembly genCategory
has pdbx struct oper list category: pdbx struct oper listCategory
has pdbx validate close contact category: pdbx validate close contactCategory
has pdbx validate rmsd angle category: pdbx validate rmsd angleCategory
has pdbx validate torsion category: pdbx validate torsionCategory
has refine category: refineCategory
has refine hist category: refine histCategory
has refine ls restr category: refine ls restrCategory
has refine ls shell category: refine ls shellCategory
has reflns category: reflnsCategory
has reflns shell category: reflns shellCategory
has software category: softwareCategory
has struct category: structCategory
has struct asym category: struct asymCategory
has struct conf category: struct confCategory
has struct conf type category: struct conf typeCategory
has struct keywords category: struct keywordsCategory
has struct ref category: struct refCategory
has struct ref seq category: struct ref seqCategory
has struct ref seq dif category: struct ref seq difCategory
has struct site category: struct siteCategory
has struct site gen category: struct site genCategory
has symmetry category: symmetryCategory

4UIY
type: atom sites
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
atom sites.entry id: 4UIY
atom sites.fract transf matrix11: 0.026774
atom sites.fract transf matrix12: 0
atom sites.fract transf matrix13: 0
atom sites.fract transf matrix21: 0
atom sites.fract transf matrix22: 0.022604
atom sites.fract transf matrix23: 0
atom sites.fract transf matrix31: 0
atom sites.fract transf matrix32: 0
atom sites.fract transf matrix33: 0.012716
atom sites.fract transf vector1: 0
atom sites.fract transf vector2: 0
atom sites.fract transf vector3: 0

4UIY
referenced by atom sites: 4UIY
referenced by cell: 4UIY
referenced by database PDB matrix: 4UIY
type: entry
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
entry.id: 4UIY
referenced by exptl: 4UIY,X-RAY DIFFRACTION
referenced by refine: 4UIY,X-RAY DIFFRACTION
referenced by reflns: http://rdf.wwpdb.org/pdb/4UIY/reflns/1
referenced by struct: 4UIY
referenced by struct keywords: 4UIY
referenced by symmetry: 4UIY
referenced by pdbx database status: 4UIY

http://rdf.wwpdb.org/pdb/4UIY/atom_type/C
type: atom type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
atom type.symbol: C

http://rdf.wwpdb.org/pdb/4UIY/atom_type/F
type: atom type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
atom type.symbol: F

http://rdf.wwpdb.org/pdb/4UIY/atom_type/N
type: atom type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
atom type.symbol: N

http://rdf.wwpdb.org/pdb/4UIY/atom_type/O
type: atom type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
atom type.symbol: O

http://rdf.wwpdb.org/pdb/4UIY/atom_type/S
type: atom type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
atom type.symbol: S

http://rdf.wwpdb.org/pdb/4UIY/audit_author/1
type: audit author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
audit author.pdbx ordinal: 1
audit author.name: Chung, C.

http://rdf.wwpdb.org/pdb/4UIY/audit_author/2
type: audit author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
audit author.pdbx ordinal: 2
audit author.name: Theodoulou, N.T.

http://rdf.wwpdb.org/pdb/4UIY/audit_author/3
type: audit author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
audit author.pdbx ordinal: 3
audit author.name: Bamborough, P.

http://rdf.wwpdb.org/pdb/4UIY/audit_author/4
type: audit author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
audit author.pdbx ordinal: 4
audit author.name: Humphreys, P.G.

mmcif pdbx.dic,5.284
type: audit conform
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
audit conform.dict name: mmcif_pdbx.dic
audit conform.dict version: 5.284
audit conform.dict location: http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic

4UIY
type: cell
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
cell.entry id: 4UIY
cell.z PDB: 4
cell.angle alpha: 90
cell.angle beta: 90
cell.angle gamma: 90
cell.length a: 37.35
cell.length b: 44.24
cell.length c: 78.64

5V2
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: 5V2
chem comp.formula: C21 H20 F3 N3 O3 S2
chem comp.formula weight: 483.527
chem comp.name: N-[1,1-bis(oxidanylidene)thian-4-yl]-5-methyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
chem comp.type: non-polymer
link to chem comp: 5V2

ALA
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: ALA
chem comp.formula: C3 H7 N O2
chem comp.formula weight: 89.093
chem comp.mon nstd flag: y
chem comp.name: ALANINE
chem comp.type: L-peptide linking
link to chem comp: ALA
referenced by entity poly seq: 1,ALA,111
referenced by entity poly seq: 1,ALA,39
referenced by entity poly seq: 1,ALA,48
referenced by entity poly seq: 1,ALA,81
referenced by entity poly seq: 1,ALA,109

ARG
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: ARG
chem comp.formula: C6 H15 N4 O2 1
chem comp.formula weight: 175.209
chem comp.mon nstd flag: y
chem comp.name: ARGININE
chem comp.type: L-peptide linking
link to chem comp: ARG
referenced by entity poly seq: 1,ARG,72
referenced by entity poly seq: 1,ARG,17
referenced by entity poly seq: 1,ARG,27

ASN
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: ASN
chem comp.formula: C4 H8 N2 O3
chem comp.formula weight: 132.118
chem comp.mon nstd flag: y
chem comp.name: ASPARAGINE
chem comp.type: L-peptide linking
link to chem comp: ASN
referenced by entity poly seq: 1,ASN,121
referenced by entity poly seq: 1,ASN,3
referenced by entity poly seq: 1,ASN,11
referenced by entity poly seq: 1,ASN,13
referenced by entity poly seq: 1,ASN,20
referenced by entity poly seq: 1,ASN,52
referenced by entity poly seq: 1,ASN,75
referenced by entity poly seq: 1,ASN,76
referenced by entity poly seq: 1,ASN,80
referenced by entity poly seq: 1,ASN,89
referenced by entity poly seq: 1,ASN,94
referenced by entity poly seq: 1,ASN,99

ASP
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: ASP
chem comp.formula: C4 H7 N O4
chem comp.formula weight: 133.103
chem comp.mon nstd flag: y
chem comp.name: ASPARTIC ACID
chem comp.type: L-peptide linking
link to chem comp: ASP
referenced by entity poly seq: 1,ASP,104
referenced by entity poly seq: 1,ASP,47
referenced by entity poly seq: 1,ASP,55
referenced by entity poly seq: 1,ASP,65
referenced by entity poly seq: 1,ASP,87
referenced by entity poly seq: 1,ASP,103

CYS
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: CYS
chem comp.formula: C3 H7 N O2 S
chem comp.formula weight: 121.158
chem comp.mon nstd flag: y
chem comp.name: CYSTEINE
chem comp.type: L-peptide linking
link to chem comp: CYS
referenced by entity poly seq: 1,CYS,95
referenced by entity poly seq: 1,CYS,84

EDO
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: EDO
chem comp.formula: C2 H6 O2
chem comp.formula weight: 62.068
chem comp.name: 1,2-ETHANEDIOL
chem comp.pdbx synonyms: ETHYLENE GLYCOL
chem comp.type: non-polymer
link to chem comp: EDO

GLN
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: GLN
chem comp.formula: C5 H10 N2 O3
chem comp.formula weight: 146.144
chem comp.mon nstd flag: y
chem comp.name: GLUTAMINE
chem comp.type: L-peptide linking
link to chem comp: GLN
referenced by entity poly seq: 1,GLN,118
referenced by entity poly seq: 1,GLN,18
referenced by entity poly seq: 1,GLN,21
referenced by entity poly seq: 1,GLN,23
referenced by entity poly seq: 1,GLN,37
referenced by entity poly seq: 1,GLN,43
referenced by entity poly seq: 1,GLN,44
referenced by entity poly seq: 1,GLN,82
referenced by entity poly seq: 1,GLN,86

GLU
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: GLU
chem comp.formula: C5 H9 N O4
chem comp.formula weight: 147.129
chem comp.mon nstd flag: y
chem comp.name: GLUTAMIC ACID
chem comp.type: L-peptide linking
link to chem comp: GLU
referenced by entity poly seq: 1,GLU,127
referenced by entity poly seq: 1,GLU,8
referenced by entity poly seq: 1,GLU,74
referenced by entity poly seq: 1,GLU,83
referenced by entity poly seq: 1,GLU,110
referenced by entity poly seq: 1,GLU,113
referenced by entity poly seq: 1,GLU,122
referenced by entity poly seq: 1,GLU,126

GLY
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: GLY
chem comp.formula: C2 H5 N O2
chem comp.formula weight: 75.067
chem comp.mon nstd flag: y
chem comp.name: GLYCINE
chem comp.type: peptide linking
link to chem comp: GLY
referenced by entity poly seq: 1,GLY,102
referenced by entity poly seq: 1,GLY,67

HIS
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: HIS
chem comp.formula: C6 H10 N3 O2 1
chem comp.formula weight: 156.162
chem comp.mon nstd flag: y
chem comp.name: HISTIDINE
chem comp.type: L-peptide linking
link to chem comp: HIS
referenced by entity poly seq: 1,HIS,36

HOH
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: HOH
chem comp.formula: H2 O
chem comp.formula weight: 18.015
chem comp.name: WATER
chem comp.type: non-polymer
link to chem comp: HOH
referenced by pdbx distant solvent atoms: http://rdf.wwpdb.org/pdb/4UIY/pdbx_distant_solvent_atoms/2
referenced by pdbx distant solvent atoms: http://rdf.wwpdb.org/pdb/4UIY/pdbx_distant_solvent_atoms/1

ILE
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: ILE
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: ISOLEUCINE
chem comp.type: L-peptide linking
link to chem comp: ILE
referenced by entity poly seq: 1,ILE,120
referenced by entity poly seq: 1,ILE,59
referenced by entity poly seq: 1,ILE,60
referenced by entity poly seq: 1,ILE,69
referenced by entity poly seq: 1,ILE,85
referenced by entity poly seq: 1,ILE,97
referenced by entity poly seq: 1,ILE,105

LEU
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: LEU
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: LEUCINE
chem comp.type: L-peptide linking
link to chem comp: LEU
referenced by entity poly seq: 1,LEU,123
referenced by entity poly seq: 1,LEU,22
referenced by entity poly seq: 1,LEU,25
referenced by entity poly seq: 1,LEU,26
referenced by entity poly seq: 1,LEU,30
referenced by entity poly seq: 1,LEU,33
referenced by entity poly seq: 1,LEU,51
referenced by entity poly seq: 1,LEU,53
referenced by entity poly seq: 1,LEU,73
referenced by entity poly seq: 1,LEU,107
referenced by entity poly seq: 1,LEU,112
referenced by entity poly seq: 1,LEU,115
referenced by entity poly seq: 1,LEU,117

LYS
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: LYS
chem comp.formula: C6 H15 N2 O2 1
chem comp.formula weight: 147.195
chem comp.mon nstd flag: y
chem comp.name: LYSINE
chem comp.type: L-peptide linking
link to chem comp: LYS
referenced by entity poly seq: 1,LYS,119
referenced by entity poly seq: 1,LYS,14
referenced by entity poly seq: 1,LYS,16
referenced by entity poly seq: 1,LYS,31
referenced by entity poly seq: 1,LYS,35
referenced by entity poly seq: 1,LYS,50
referenced by entity poly seq: 1,LYS,58
referenced by entity poly seq: 1,LYS,61
referenced by entity poly seq: 1,LYS,70
referenced by entity poly seq: 1,LYS,71
referenced by entity poly seq: 1,LYS,100
referenced by entity poly seq: 1,LYS,114

MET
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: MET
chem comp.formula: C5 H11 N O2 S
chem comp.formula weight: 149.211
chem comp.mon nstd flag: y
chem comp.name: METHIONINE
chem comp.type: L-peptide linking
link to chem comp: MET
referenced by entity poly seq: 1,MET,108
referenced by entity poly seq: 1,MET,2
referenced by entity poly seq: 1,MET,64
referenced by entity poly seq: 1,MET,66
referenced by entity poly seq: 1,MET,91

PHE
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: PHE
chem comp.formula: C9 H11 N O2
chem comp.formula weight: 165.189
chem comp.mon nstd flag: y
chem comp.name: PHENYLALANINE
chem comp.type: L-peptide linking
link to chem comp: PHE
referenced by entity poly seq: 1,PHE,116
referenced by entity poly seq: 1,PHE,38
referenced by entity poly seq: 1,PHE,42
referenced by entity poly seq: 1,PHE,88
referenced by entity poly seq: 1,PHE,92

PRO
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: PRO
chem comp.formula: C5 H9 N O2
chem comp.formula weight: 115.13
chem comp.mon nstd flag: y
chem comp.name: PROLINE
chem comp.type: L-peptide linking
link to chem comp: PRO
referenced by entity poly seq: 1,PRO,124
referenced by entity poly seq: 1,PRO,4
referenced by entity poly seq: 1,PRO,5
referenced by entity poly seq: 1,PRO,6
referenced by entity poly seq: 1,PRO,7
referenced by entity poly seq: 1,PRO,12
referenced by entity poly seq: 1,PRO,15
referenced by entity poly seq: 1,PRO,41
referenced by entity poly seq: 1,PRO,45
referenced by entity poly seq: 1,PRO,54
referenced by entity poly seq: 1,PRO,63
referenced by entity poly seq: 1,PRO,101

SER
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: SER
chem comp.formula: C3 H7 N O3
chem comp.formula weight: 105.093
chem comp.mon nstd flag: y
chem comp.name: SERINE
chem comp.type: L-peptide linking
link to chem comp: SER
referenced by entity poly seq: 1,SER,10
referenced by entity poly seq: 1,SER,1

THR
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: THR
chem comp.formula: C4 H9 N O3
chem comp.formula weight: 119.119
chem comp.mon nstd flag: y
chem comp.name: THREONINE
chem comp.type: L-peptide linking
link to chem comp: THR
referenced by entity poly seq: 1,THR,125
referenced by entity poly seq: 1,THR,9
referenced by entity poly seq: 1,THR,19
referenced by entity poly seq: 1,THR,32
referenced by entity poly seq: 1,THR,62
referenced by entity poly seq: 1,THR,68
referenced by entity poly seq: 1,THR,90
referenced by entity poly seq: 1,THR,93

TRP
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: TRP
chem comp.formula: C11 H12 N2 O2
chem comp.formula weight: 204.225
chem comp.mon nstd flag: y
chem comp.name: TRYPTOPHAN
chem comp.type: L-peptide linking
link to chem comp: TRP
referenced by entity poly seq: 1,TRP,79
referenced by entity poly seq: 1,TRP,34
referenced by entity poly seq: 1,TRP,40

TYR
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: TYR
chem comp.formula: C9 H11 N O3
chem comp.formula weight: 181.189
chem comp.mon nstd flag: y
chem comp.name: TYROSINE
chem comp.type: L-peptide linking
link to chem comp: TYR
referenced by entity poly seq: 1,TYR,98
referenced by entity poly seq: 1,TYR,24
referenced by entity poly seq: 1,TYR,56
referenced by entity poly seq: 1,TYR,57
referenced by entity poly seq: 1,TYR,77
referenced by entity poly seq: 1,TYR,78
referenced by entity poly seq: 1,TYR,96

VAL
type: chem comp
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
chem comp.id: VAL
chem comp.formula: C5 H11 N O2
chem comp.formula weight: 117.146
chem comp.mon nstd flag: y
chem comp.name: VALINE
chem comp.type: L-peptide linking
link to chem comp: VAL
referenced by entity poly seq: 1,VAL,106
referenced by entity poly seq: 1,VAL,28
referenced by entity poly seq: 1,VAL,29
referenced by entity poly seq: 1,VAL,46
referenced by entity poly seq: 1,VAL,49

primary
type: citation
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
citation.id: primary
citation.country: US
citation.journal abbrev: J.Med.Chem.
citation.journal id ASTM: JMCMAR
citation.journal id CSD: 0151
citation.journal id ISSN: 0022-2623
citation.journal volume: 59
citation.page first: 1425
citation.pdbx database id DOI: 10.1021/ACS.JMEDCHEM.5B00256
citation.pdbx database id pub med: 25856009
citation.title: The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
citation.year: 2016
link to doi: doi:10.1021/ACS.JMEDCHEM.5B00256
link to pubmed: pubmed:25856009
references: pubmed:25856009
referenced by citation author: primary,Humphreys, P.G.,21
referenced by citation author: primary,Theodoulou, N.H.,1
referenced by citation author: primary,Bamborough, P.,2
referenced by citation author: primary,Bannister, A.J.,3
referenced by citation author: primary,Becher, I.,4
referenced by citation author: primary,Bit, R.A.,5
referenced by citation author: primary,Che, K.H.,6
referenced by citation author: primary,Chung, C.,7
referenced by citation author: primary,Dittmann, A.,8
referenced by citation author: primary,Drewes, G.,9
referenced by citation author: primary,Drewry, D.H.,10
referenced by citation author: primary,Gordon, L.,11
referenced by citation author: primary,Grandi, P.,12
referenced by citation author: primary,Leveridge, M.,13
referenced by citation author: primary,Lindon, M.,14
referenced by citation author: primary,Michon, A.,15
referenced by citation author: primary,Molnar, J.,16
referenced by citation author: primary,Robson, S.C.,17
referenced by citation author: primary,Tomkinson, N.C.O.,18
referenced by citation author: primary,Kouzarides, T.,19
referenced by citation author: primary,Prinjha, R.K.,20

primary,Theodoulou, N.H.,1
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Theodoulou, N.H.
citation author.ordinal: 1

primary,Bamborough, P.,2
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Bamborough, P.
citation author.ordinal: 2

primary,Bannister, A.J.,3
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Bannister, A.J.
citation author.ordinal: 3

primary,Becher, I.,4
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Becher, I.
citation author.ordinal: 4

primary,Bit, R.A.,5
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Bit, R.A.
citation author.ordinal: 5

primary,Che, K.H.,6
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Che, K.H.
citation author.ordinal: 6

primary,Chung, C.,7
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Chung, C.
citation author.ordinal: 7

primary,Dittmann, A.,8
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Dittmann, A.
citation author.ordinal: 8

primary,Drewes, G.,9
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Drewes, G.
citation author.ordinal: 9

primary,Drewry, D.H.,10
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Drewry, D.H.
citation author.ordinal: 10

primary,Gordon, L.,11
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Gordon, L.
citation author.ordinal: 11

primary,Grandi, P.,12
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Grandi, P.
citation author.ordinal: 12

primary,Leveridge, M.,13
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Leveridge, M.
citation author.ordinal: 13

primary,Lindon, M.,14
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Lindon, M.
citation author.ordinal: 14

primary,Michon, A.,15
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Michon, A.
citation author.ordinal: 15

primary,Molnar, J.,16
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Molnar, J.
citation author.ordinal: 16

primary,Robson, S.C.,17
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Robson, S.C.
citation author.ordinal: 17

primary,Tomkinson, N.C.O.,18
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Tomkinson, N.C.O.
citation author.ordinal: 18

primary,Kouzarides, T.,19
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Kouzarides, T.
citation author.ordinal: 19

primary,Prinjha, R.K.,20
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Prinjha, R.K.
citation author.ordinal: 20

primary,Humphreys, P.G.,21
type: citation author
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to citation: primary
citation author.citation id: primary
citation author.name: Humphreys, P.G.
citation author.ordinal: 21

4UIY,PDB
type: database 2
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
database 2.database code: 4UIY
database 2.database id: PDB

EBI-63544,PDBE
type: database 2
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
database 2.database code: EBI-63544
database 2.database id: PDBE

D 1290063544,WWPDB
type: database 2
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
database 2.database code: D_1290063544
database 2.database id: WWPDB

4UIY
type: database PDB matrix
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
database PDB matrix.entry id: 4UIY
database PDB matrix.origx11: 1
database PDB matrix.origx12: 0
database PDB matrix.origx13: 0
database PDB matrix.origx21: 0
database PDB matrix.origx22: 1
database PDB matrix.origx23: 0
database PDB matrix.origx31: 0
database PDB matrix.origx32: 0
database PDB matrix.origx33: 1
database PDB matrix.origx vector1: 0
database PDB matrix.origx vector2: 0
database PDB matrix.origx vector3: 0

http://rdf.wwpdb.org/pdb/4UIY/diffrn/1
type: diffrn
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to exptl crystal: http://rdf.wwpdb.org/pdb/4UIY/exptl_crystal/1
diffrn.id: 1
diffrn.ambient temp: 100
diffrn.crystal id: 1
referenced by diffrn detector: http://rdf.wwpdb.org/pdb/4UIY/diffrn_detector/1
referenced by diffrn radiation: http://rdf.wwpdb.org/pdb/4UIY/diffrn_radiation/1
referenced by diffrn source: http://rdf.wwpdb.org/pdb/4UIY/diffrn_source/1

http://rdf.wwpdb.org/pdb/4UIY/exptl_crystal/1
referenced by diffrn: http://rdf.wwpdb.org/pdb/4UIY/diffrn/1
type: exptl crystal
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
exptl crystal.id: 1
exptl crystal.density matthews: 2.15
exptl crystal.density percent sol: 42.83
exptl crystal.description: NONE
referenced by exptl crystal grow: http://rdf.wwpdb.org/pdb/4UIY/exptl_crystal_grow/1

http://rdf.wwpdb.org/pdb/4UIY/diffrn_detector/1
type: diffrn detector
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to diffrn: http://rdf.wwpdb.org/pdb/4UIY/diffrn/1
diffrn detector.diffrn id: 1
diffrn detector.detector: PIXEL
diffrn detector.pdbx collection date: 2014-01-27
diffrn detector.type: DECTRIS PILATUS 6M

http://rdf.wwpdb.org/pdb/4UIY/diffrn_radiation/1
type: diffrn radiation
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to diffrn: http://rdf.wwpdb.org/pdb/4UIY/diffrn/1
diffrn radiation.diffrn id: 1
diffrn radiation.pdbx diffrn protocol: SINGLE WAVELENGTH
diffrn radiation.pdbx monochromatic or laue m l: M
diffrn radiation.pdbx scattering type: x-ray
diffrn radiation.wavelength id: 1

http://rdf.wwpdb.org/pdb/4UIY/diffrn_radiation_wavelength/1
type: diffrn radiation wavelength
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
diffrn radiation wavelength.id: 1
diffrn radiation wavelength.wavelength: 0.97625
diffrn radiation wavelength.wt: 1

http://rdf.wwpdb.org/pdb/4UIY/diffrn_source/1
type: diffrn source
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to diffrn: http://rdf.wwpdb.org/pdb/4UIY/diffrn/1
diffrn source.diffrn id: 1
diffrn source.pdbx synchrotron beamline: ID29
diffrn source.pdbx synchrotron site: ESRF
diffrn source.pdbx wavelength: 0.97625
diffrn source.source: SYNCHROTRON
diffrn source.type: ESRF BEAMLINE ID29

http://rdf.wwpdb.org/pdb/4UIY/entity/1
type: entity
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
entity.id: 1
entity.formula weight: 15099.38
entity.pdbx description: BROMODOMAIN-CONTAINING PROTEIN 4
entity.pdbx fragment: N-TERMINAL BROMODOMAIN, RESIDUES 44-168
entity.pdbx number of molecules: 1
entity.src method: man
entity.type: polymer
referenced by entity name com: http://rdf.wwpdb.org/pdb/4UIY/entity_name_com/1
referenced by entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
referenced by struct ref: http://rdf.wwpdb.org/pdb/4UIY/struct_ref/1
referenced by entity src gen: 1,1

http://rdf.wwpdb.org/pdb/4UIY/entity/2
type: entity
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
entity.id: 2
entity.formula weight: 62.068
entity.pdbx description: 1,2-ETHANEDIOL
entity.pdbx number of molecules: 3
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/D
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/2
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/B
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/C

http://rdf.wwpdb.org/pdb/4UIY/entity/3
type: entity
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
entity.id: 3
entity.formula weight: 483.527
entity.pdbx description: N-[1,1-bis(oxidanylidene)thian-4-yl]-5-methyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
entity.pdbx number of molecules: 1
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/E
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/3

http://rdf.wwpdb.org/pdb/4UIY/entity/4
type: entity
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
entity.id: 4
entity.formula weight: 18.015
entity.pdbx description: water
entity.pdbx number of molecules: 264
entity.src method: nat
entity.type: water
referenced by struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/F
referenced by pdbx entity nonpoly: http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/4

http://rdf.wwpdb.org/pdb/4UIY/entity_name_com/1
type: entity name com
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/1
entity name com.entity id: 1
entity name com.name: PROTEIN HUNK1, HUMAN BRD4

http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
type: entity poly
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/1
entity poly.entity id: 1
entity poly.nstd linkage: no
entity poly.nstd monomer: no
entity poly.pdbx seq one letter code: SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE
entity poly.pdbx seq one letter code can: SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWN AQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE
entity poly.pdbx strand id: A
entity poly.type: polypeptide(L)
referenced by entity poly seq: 1,GLU,127
referenced by entity poly seq: 1,SER,1
referenced by entity poly seq: 1,MET,2
referenced by entity poly seq: 1,ASN,3
referenced by entity poly seq: 1,PRO,4
referenced by entity poly seq: 1,PRO,5
referenced by entity poly seq: 1,PRO,6
referenced by entity poly seq: 1,PRO,7
referenced by entity poly seq: 1,GLU,8
referenced by entity poly seq: 1,THR,9
referenced by entity poly seq: 1,SER,10
referenced by entity poly seq: 1,ASN,11
referenced by entity poly seq: 1,PRO,12
referenced by entity poly seq: 1,ASN,13
referenced by entity poly seq: 1,LYS,14
referenced by entity poly seq: 1,PRO,15
referenced by entity poly seq: 1,LYS,16
referenced by entity poly seq: 1,ARG,17
referenced by entity poly seq: 1,GLN,18
referenced by entity poly seq: 1,THR,19
referenced by entity poly seq: 1,ASN,20
referenced by entity poly seq: 1,GLN,21
referenced by entity poly seq: 1,LEU,22
referenced by entity poly seq: 1,GLN,23
referenced by entity poly seq: 1,TYR,24
referenced by entity poly seq: 1,LEU,25
referenced by entity poly seq: 1,LEU,26
referenced by entity poly seq: 1,ARG,27
referenced by entity poly seq: 1,VAL,28
referenced by entity poly seq: 1,VAL,29
referenced by entity poly seq: 1,LEU,30
referenced by entity poly seq: 1,LYS,31
referenced by entity poly seq: 1,THR,32
referenced by entity poly seq: 1,LEU,33
referenced by entity poly seq: 1,TRP,34
referenced by entity poly seq: 1,LYS,35
referenced by entity poly seq: 1,HIS,36
referenced by entity poly seq: 1,GLN,37
referenced by entity poly seq: 1,PHE,38
referenced by entity poly seq: 1,ALA,39
referenced by entity poly seq: 1,TRP,40
referenced by entity poly seq: 1,PRO,41
referenced by entity poly seq: 1,PHE,42
referenced by entity poly seq: 1,GLN,43
referenced by entity poly seq: 1,GLN,44
referenced by entity poly seq: 1,PRO,45
referenced by entity poly seq: 1,VAL,46
referenced by entity poly seq: 1,ASP,47
referenced by entity poly seq: 1,ALA,48
referenced by entity poly seq: 1,VAL,49
referenced by entity poly seq: 1,LYS,50
referenced by entity poly seq: 1,LEU,51
referenced by entity poly seq: 1,ASN,52
referenced by entity poly seq: 1,LEU,53
referenced by entity poly seq: 1,PRO,54
referenced by entity poly seq: 1,ASP,55
referenced by entity poly seq: 1,TYR,56
referenced by entity poly seq: 1,TYR,57
referenced by entity poly seq: 1,LYS,58
referenced by entity poly seq: 1,ILE,59
referenced by entity poly seq: 1,ILE,60
referenced by entity poly seq: 1,LYS,61
referenced by entity poly seq: 1,THR,62
referenced by entity poly seq: 1,PRO,63
referenced by entity poly seq: 1,MET,64
referenced by entity poly seq: 1,ASP,65
referenced by entity poly seq: 1,MET,66
referenced by entity poly seq: 1,GLY,67
referenced by entity poly seq: 1,THR,68
referenced by entity poly seq: 1,ILE,69

1,SER,1
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 1
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,1

1,MET,2
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 2
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,2

1,ASN,3
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 3
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,3

1,PRO,4
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 4
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,4

1,PRO,5
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 5
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,5

1,PRO,6
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 6
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,6

1,PRO,7
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 7
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,7

1,GLU,8
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 8
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,8

1,THR,9
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 9
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,9

1,SER,10
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 10
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,SER,10

1,ASN,11
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 11
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,11

1,PRO,12
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 12
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,12

1,ASN,13
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 13
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,13

1,LYS,14
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 14
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,14

1,PRO,15
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 15
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,15

1,LYS,16
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 16
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,16

1,ARG,17
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 17
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,17

1,GLN,18
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 18
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,18

1,THR,19
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 19
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,19

1,ASN,20
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 20
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,20

1,GLN,21
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 21
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,21

1,LEU,22
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 22
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,22

1,GLN,23
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 23
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,23

1,TYR,24
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 24
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,24

1,LEU,25
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 25
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,25

1,LEU,26
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 26
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,26

1,ARG,27
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 27
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,27

1,VAL,28
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 28
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,28

1,VAL,29
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 29
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,29

1,LEU,30
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 30
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,30

1,LYS,31
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 31
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,31

1,THR,32
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 32
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,32

1,LEU,33
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 33
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,33

1,TRP,34
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 34
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,34

1,LYS,35
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 35
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,35

1,HIS,36
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 36
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,HIS,36

1,GLN,37
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 37
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,37

1,PHE,38
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 38
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,38

1,ALA,39
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 39
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,39

1,TRP,40
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 40
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,40

1,PRO,41
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 41
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,41

1,PHE,42
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 42
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,42

1,GLN,43
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 43
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,43

1,GLN,44
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 44
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,44

1,PRO,45
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 45
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,45

1,VAL,46
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 46
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,46

1,ASP,47
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 47
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,47

1,ALA,48
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 48
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,48

1,VAL,49
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 49
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,49

1,LYS,50
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 50
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,50

1,LEU,51
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 51
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,51

1,ASN,52
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 52
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,52

1,LEU,53
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 53
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,53

1,PRO,54
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 54
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,54

1,ASP,55
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 55
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,55

1,TYR,56
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 56
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,56

1,TYR,57
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 57
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,57

1,LYS,58
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 58
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,58

1,ILE,59
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 59
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,59

1,ILE,60
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 60
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,60

1,LYS,61
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 61
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,61

1,THR,62
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 62
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,62

1,PRO,63
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 63
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,63

1,MET,64
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 64
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,64

1,ASP,65
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 65
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,65

1,MET,66
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 66
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,66

1,GLY,67
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 67
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,67

1,THR,68
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 68
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,68

1,ILE,69
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 69
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,69

1,LYS,70
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 70
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,70

1,LYS,71
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 71
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,71

1,ARG,72
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 72
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ARG,72

1,LEU,73
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 73
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,73

1,GLU,74
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 74
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,74

1,ASN,75
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 75
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,75

1,ASN,76
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 76
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,76

1,TYR,77
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 77
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,77

1,TYR,78
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 78
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,78

1,TRP,79
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 79
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TRP,79

1,ASN,80
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 80
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,80

1,ALA,81
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 81
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,81

1,GLN,82
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 82
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,82

1,GLU,83
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 83
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,83

1,CYS,84
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 84
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,84

1,ILE,85
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 85
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,85

1,GLN,86
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 86
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,86

1,ASP,87
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 87
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,87

1,PHE,88
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 88
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,88

1,ASN,89
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 89
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,89

1,THR,90
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 90
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,90

1,MET,91
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 91
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,91

1,PHE,92
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 92
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,92

1,THR,93
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 93
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,93

1,ASN,94
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 94
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,94

1,CYS,95
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 95
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,CYS,95

1,TYR,96
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 96
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,96

1,ILE,97
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 97
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,97

1,TYR,98
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 98
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,TYR,98

1,ASN,99
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 99
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,99

1,LYS,100
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 100
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,100

1,PRO,101
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 101
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,101

1,GLY,102
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 102
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLY,102

1,ASP,103
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 103
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,103

1,ASP,104
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 104
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASP,104

1,ILE,105
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 105
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,105

1,VAL,106
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 106
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,VAL,106

1,LEU,107
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 107
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,107

1,MET,108
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 108
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,MET,108

1,ALA,109
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 109
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,109

1,GLU,110
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 110
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,110

1,ALA,111
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 111
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ALA,111

1,LEU,112
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 112
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,112

1,GLU,113
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 113
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,113

1,LYS,114
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 114
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,114

1,LEU,115
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 115
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,115

1,PHE,116
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 116
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PHE,116

1,LEU,117
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 117
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,117

1,GLN,118
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 118
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLN,118

1,LYS,119
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 119
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LYS,119

1,ILE,120
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 120
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ILE,120

1,ASN,121
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 121
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,ASN,121

1,GLU,122
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 122
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,122

1,LEU,123
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 123
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,LEU,123

1,PRO,124
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 124
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,PRO,124

1,THR,125
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 125
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,THR,125

1,GLU,126
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 126
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,126

1,GLU,127
type: entity poly seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4UIY/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 127
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: A,1,GLU,127

1,1
type: entity src gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/1
entity src gen.entity id: 1
entity src gen.pdbx src id: 1
entity src gen.gene src common name: HUMAN
entity src gen.pdbx alt source flag: sample
entity src gen.pdbx gene src ncbi taxonomy id: 9606
entity src gen.pdbx gene src scientific name: HOMO SAPIENS
entity src gen.pdbx host org ncbi taxonomy id: 562
entity src gen.pdbx host org scientific name: ESCHERICHIA COLI
link to taxonomy source: taxonomy:9606
link to taxonomy host: taxonomy:562

taxonomy:9606

taxonomy:562

4UIY,X-RAY DIFFRACTION
type: exptl
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
exptl.entry id: 4UIY
exptl.method: X-RAY DIFFRACTION
exptl.crystals number: 1

http://rdf.wwpdb.org/pdb/4UIY/exptl_crystal_grow/1
type: exptl crystal grow
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to exptl crystal: http://rdf.wwpdb.org/pdb/4UIY/exptl_crystal/1
exptl crystal grow.crystal id: 1
exptl crystal grow.p h: 7.5
exptl crystal grow.pdbx details: 20% PEG3350, 0.2M KSCN, 0.1M BTP PH 7.5

Structure model,1,3
type: pdbx audit revision category
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 1
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: diffrn_detector

Structure model,3
referenced by pdbx audit revision category: Structure model,1,3
referenced by pdbx audit revision group: Structure model,2,3
type: pdbx audit revision history
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 3
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 2
pdbx audit revision history.revision date: 2017-09-27
referenced by pdbx audit revision item: Structure model,1,3

Structure model,1,1
type: pdbx audit revision details
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx audit revision history: Structure model,1
pdbx audit revision details.data content type: Structure model
pdbx audit revision details.ordinal: 1
pdbx audit revision details.revision ordinal: 1
pdbx audit revision details.provider: repository
pdbx audit revision details.type: Initial release

Structure model,1
referenced by pdbx audit revision details: Structure model,1,1
type: pdbx audit revision history
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 1
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 0
pdbx audit revision history.revision date: 2015-04-22

Structure model,1,2
type: pdbx audit revision group
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx audit revision history: Structure model,2
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 1
pdbx audit revision group.revision ordinal: 2
pdbx audit revision group.group: Database references

Structure model,2
referenced by pdbx audit revision group: Structure model,1,2
type: pdbx audit revision history
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 2
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 1
pdbx audit revision history.revision date: 2016-03-09

Structure model,2,3
type: pdbx audit revision group
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 2
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Data collection

Structure model,1,3
type: pdbx audit revision item
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 1
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _diffrn_detector.type

unspecified,4UIT,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIT
pdbx database related.db name: PDB
pdbx database related.details: BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-DIMETHOXYPHENYL )-2-(4-METHANESULFONYLPIPERAZINE-1-CARBONYL)-5-METHYL- 4H,5H-THIENO-3,2-C-PYRIDIN-4-ONE

unspecified,4UIU,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIU
pdbx database related.db name: PDB
pdbx database related.details: BROMODOMAIN OF HUMAN BRD9 WITH 7-(3,4-DIMETHOXYPHENYL )-N-(1,1-DIOXO-1-THIAN-4-YL)-5-METHYL-4-OXO- 4H,5H-THIENO-3,2-C-PYRIDINE-2-CARBOXAMIDE

unspecified,4UIV,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIV
pdbx database related.db name: PDB
pdbx database related.details: BROMODOMAIN OF HUMAN BRD9 WITH N-(1,1-DIOXO-1- THIAN-4-YL)-5-METHYL-4-OXO-7-3-(TRIFLUOROMETHYL) PHENYL-4H,5H-THIENO-3,2-C-PYRIDINE-2-CARBOXIMIDAMIDE

unspecified,4UIW,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIW
pdbx database related.db name: PDB
pdbx database related.details: BROMODOMAIN OF HUMAN BRD9 WITH N-(1,1-DIOXO-1- THIAN-4-YL)-5-ETHYL-4-OXO-7-3-(TRIFLUOROMETHYL) PHENYL-4H,5H-THIENO-3,2-C-PYRIDINE-2-CARBOXIMIDAMIDE

unspecified,4UIX,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIX
pdbx database related.db name: PDB
pdbx database related.details: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4- DIMETHOXYPHENYL)-N-(1,1-DIOXO-1-THIAN-4-YL)-5- METHYL-4-OXO-4H,5H-THIENO-3,2-C-PYRIDINE-2- CARBOXAMIDE

unspecified,4UIZ,PDB
type: pdbx database related
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx database related.content type: unspecified
pdbx database related.db id: 4UIZ
pdbx database related.db name: PDB
pdbx database related.details: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4- DIMETHOXYPHENYL)-2-(4-METHANESULFONYLPIPERAZINE-1-CARBONYL )-5-METHYL-4H,5H-THIENO-3,2-C-PYRIDIN-4-ONE

4UIY
type: pdbx database status
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
pdbx database status.entry id: 4UIY
pdbx database status.deposit site: PDBE
pdbx database status.pdb format compatible: Y
pdbx database status.process site: PDBE
pdbx database status.recvd initial deposition date: 2015-04-03
pdbx database status.status code: REL

http://rdf.wwpdb.org/pdb/4UIY/pdbx_distant_solvent_atoms/1
type: pdbx distant solvent atoms
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: HOH
pdbx distant solvent atoms.id: 1
pdbx distant solvent atoms.pdb model num: 1
pdbx distant solvent atoms.auth asym id: A
pdbx distant solvent atoms.auth atom id: O
pdbx distant solvent atoms.auth comp id: HOH
pdbx distant solvent atoms.auth seq id: 2031
pdbx distant solvent atoms.neighbor macromolecule distance: 7.23

http://rdf.wwpdb.org/pdb/4UIY/pdbx_distant_solvent_atoms/2
type: pdbx distant solvent atoms
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to chem comp: HOH
pdbx distant solvent atoms.id: 2
pdbx distant solvent atoms.pdb model num: 1
pdbx distant solvent atoms.auth asym id: A
pdbx distant solvent atoms.auth atom id: O
pdbx distant solvent atoms.auth comp id: HOH
pdbx distant solvent atoms.auth seq id: 2038
pdbx distant solvent atoms.neighbor macromolecule distance: 7.11

http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/2
type: pdbx entity nonpoly
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/2
pdbx entity nonpoly.entity id: 2
pdbx entity nonpoly.comp id: EDO
pdbx entity nonpoly.name: 1,2-ETHANEDIOL

http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/3
type: pdbx entity nonpoly
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/3
pdbx entity nonpoly.entity id: 3
pdbx entity nonpoly.comp id: 5V2
pdbx entity nonpoly.name: N-[1,1-bis(oxidanylidene)thian-4-yl]-5-methyl-4-oxidanylidene-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide

http://rdf.wwpdb.org/pdb/4UIY/pdbx_entity_nonpoly/4
type: pdbx entity nonpoly
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/4
pdbx entity nonpoly.entity id: 4
pdbx entity nonpoly.comp id: HOH
pdbx entity nonpoly.name: water

B,1
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: B
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: EDO
pdbx nonpoly scheme.auth seq num: 1169
pdbx nonpoly scheme.entity id: 2
pdbx nonpoly scheme.mon id: EDO
pdbx nonpoly scheme.pdb mon id: EDO
pdbx nonpoly scheme.pdb seq num: 1169
pdbx nonpoly scheme.pdb strand id: A

C,1
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: C
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: EDO
pdbx nonpoly scheme.auth seq num: 1170
pdbx nonpoly scheme.entity id: 2
pdbx nonpoly scheme.mon id: EDO
pdbx nonpoly scheme.pdb mon id: EDO
pdbx nonpoly scheme.pdb seq num: 1170
pdbx nonpoly scheme.pdb strand id: A

D,1
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: D
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: EDO
pdbx nonpoly scheme.auth seq num: 1171
pdbx nonpoly scheme.entity id: 2
pdbx nonpoly scheme.mon id: EDO
pdbx nonpoly scheme.pdb mon id: EDO
pdbx nonpoly scheme.pdb seq num: 1171
pdbx nonpoly scheme.pdb strand id: A

E,1
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: E
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: 5V2
pdbx nonpoly scheme.auth seq num: 1172
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: 5V2
pdbx nonpoly scheme.pdb mon id: 5V2
pdbx nonpoly scheme.pdb seq num: 1172
pdbx nonpoly scheme.pdb strand id: A

F,1
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2001
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2001
pdbx nonpoly scheme.pdb strand id: A

F,2
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2002
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2002
pdbx nonpoly scheme.pdb strand id: A

F,3
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2003
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2003
pdbx nonpoly scheme.pdb strand id: A

F,4
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2004
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2004
pdbx nonpoly scheme.pdb strand id: A

F,5
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2005
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2005
pdbx nonpoly scheme.pdb strand id: A

F,6
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2006
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2006
pdbx nonpoly scheme.pdb strand id: A

F,7
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2007
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2007
pdbx nonpoly scheme.pdb strand id: A

F,8
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2008
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2008
pdbx nonpoly scheme.pdb strand id: A

F,9
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2009
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2009
pdbx nonpoly scheme.pdb strand id: A

F,10
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2010
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2010
pdbx nonpoly scheme.pdb strand id: A

F,11
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2011
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2011
pdbx nonpoly scheme.pdb strand id: A

F,12
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2012
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2012
pdbx nonpoly scheme.pdb strand id: A

F,13
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2013
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2013
pdbx nonpoly scheme.pdb strand id: A

F,14
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2014
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2014
pdbx nonpoly scheme.pdb strand id: A

F,15
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2015
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2015
pdbx nonpoly scheme.pdb strand id: A

F,16
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2016
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2016
pdbx nonpoly scheme.pdb strand id: A

F,17
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2017
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2017
pdbx nonpoly scheme.pdb strand id: A

F,18
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2018
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2018
pdbx nonpoly scheme.pdb strand id: A

F,19
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2019
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2019
pdbx nonpoly scheme.pdb strand id: A

F,20
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2020
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2020
pdbx nonpoly scheme.pdb strand id: A

F,21
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2021
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2021
pdbx nonpoly scheme.pdb strand id: A

F,22
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2022
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2022
pdbx nonpoly scheme.pdb strand id: A

F,23
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2023
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2023
pdbx nonpoly scheme.pdb strand id: A

F,24
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2024
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2024
pdbx nonpoly scheme.pdb strand id: A

F,25
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2025
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2025
pdbx nonpoly scheme.pdb strand id: A

F,26
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2026
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2026
pdbx nonpoly scheme.pdb strand id: A

F,27
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2027
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2027
pdbx nonpoly scheme.pdb strand id: A

F,28
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2028
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2028
pdbx nonpoly scheme.pdb strand id: A

F,29
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2029
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2029
pdbx nonpoly scheme.pdb strand id: A

F,30
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2030
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2030
pdbx nonpoly scheme.pdb strand id: A

F,31
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2031
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2031
pdbx nonpoly scheme.pdb strand id: A

F,32
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2032
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2032
pdbx nonpoly scheme.pdb strand id: A

F,33
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2033
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2033
pdbx nonpoly scheme.pdb strand id: A

F,34
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2034
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2034
pdbx nonpoly scheme.pdb strand id: A

F,35
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2035
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2035
pdbx nonpoly scheme.pdb strand id: A

F,36
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2036
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2036
pdbx nonpoly scheme.pdb strand id: A

F,37
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2037
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2037
pdbx nonpoly scheme.pdb strand id: A

F,38
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2038
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2038
pdbx nonpoly scheme.pdb strand id: A

F,39
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2039
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2039
pdbx nonpoly scheme.pdb strand id: A

F,40
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2040
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2040
pdbx nonpoly scheme.pdb strand id: A

F,41
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2041
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2041
pdbx nonpoly scheme.pdb strand id: A

F,42
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2042
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2042
pdbx nonpoly scheme.pdb strand id: A

F,43
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2043
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2043
pdbx nonpoly scheme.pdb strand id: A

F,44
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2044
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2044
pdbx nonpoly scheme.pdb strand id: A

F,45
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2045
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2045
pdbx nonpoly scheme.pdb strand id: A

F,46
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2046
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2046
pdbx nonpoly scheme.pdb strand id: A

F,47
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2047
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2047
pdbx nonpoly scheme.pdb strand id: A

F,48
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2048
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2048
pdbx nonpoly scheme.pdb strand id: A

F,49
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2049
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2049
pdbx nonpoly scheme.pdb strand id: A

F,50
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2050
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2050
pdbx nonpoly scheme.pdb strand id: A

F,51
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2051
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2051
pdbx nonpoly scheme.pdb strand id: A

F,52
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2052
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2052
pdbx nonpoly scheme.pdb strand id: A

F,53
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2053
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2053
pdbx nonpoly scheme.pdb strand id: A

F,54
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2054
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2054
pdbx nonpoly scheme.pdb strand id: A

F,55
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2055
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2055
pdbx nonpoly scheme.pdb strand id: A

F,56
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2056
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2056
pdbx nonpoly scheme.pdb strand id: A

F,57
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2057
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2057
pdbx nonpoly scheme.pdb strand id: A

F,58
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2058
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2058
pdbx nonpoly scheme.pdb strand id: A

F,59
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2059
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2059
pdbx nonpoly scheme.pdb strand id: A

F,60
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2060
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2060
pdbx nonpoly scheme.pdb strand id: A

F,61
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2061
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2061
pdbx nonpoly scheme.pdb strand id: A

F,62
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2062
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2062
pdbx nonpoly scheme.pdb strand id: A

F,63
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2063
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2063
pdbx nonpoly scheme.pdb strand id: A

F,64
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2064
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2064
pdbx nonpoly scheme.pdb strand id: A

F,65
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2065
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2065
pdbx nonpoly scheme.pdb strand id: A

F,66
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2066
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2066
pdbx nonpoly scheme.pdb strand id: A

F,67
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2067
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2067
pdbx nonpoly scheme.pdb strand id: A

F,68
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2068
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2068
pdbx nonpoly scheme.pdb strand id: A

F,69
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2069
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2069
pdbx nonpoly scheme.pdb strand id: A

F,70
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2070
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2070
pdbx nonpoly scheme.pdb strand id: A

F,71
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2071
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2071
pdbx nonpoly scheme.pdb strand id: A

F,72
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2072
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2072
pdbx nonpoly scheme.pdb strand id: A

F,73
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2073
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2073
pdbx nonpoly scheme.pdb strand id: A

F,74
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2074
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2074
pdbx nonpoly scheme.pdb strand id: A

F,75
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2075
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2075
pdbx nonpoly scheme.pdb strand id: A

F,76
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2076
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2076
pdbx nonpoly scheme.pdb strand id: A

F,77
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2077
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2077
pdbx nonpoly scheme.pdb strand id: A

F,78
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2078
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2078
pdbx nonpoly scheme.pdb strand id: A

F,79
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2079
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2079
pdbx nonpoly scheme.pdb strand id: A

F,80
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2080
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2080
pdbx nonpoly scheme.pdb strand id: A

F,81
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2081
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2081
pdbx nonpoly scheme.pdb strand id: A

F,82
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2082
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2082
pdbx nonpoly scheme.pdb strand id: A

F,83
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2083
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2083
pdbx nonpoly scheme.pdb strand id: A

F,84
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2084
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2084
pdbx nonpoly scheme.pdb strand id: A

F,85
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2085
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2085
pdbx nonpoly scheme.pdb strand id: A

F,86
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2086
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2086
pdbx nonpoly scheme.pdb strand id: A

F,87
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2087
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2087
pdbx nonpoly scheme.pdb strand id: A

F,88
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2088
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2088
pdbx nonpoly scheme.pdb strand id: A

F,89
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2089
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2089
pdbx nonpoly scheme.pdb strand id: A

F,90
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2090
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2090
pdbx nonpoly scheme.pdb strand id: A

F,91
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2091
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2091
pdbx nonpoly scheme.pdb strand id: A

F,92
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2092
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2092
pdbx nonpoly scheme.pdb strand id: A

F,93
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2093
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2093
pdbx nonpoly scheme.pdb strand id: A

F,94
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2094
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2094
pdbx nonpoly scheme.pdb strand id: A

F,95
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2095
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2095
pdbx nonpoly scheme.pdb strand id: A

F,96
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2096
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2096
pdbx nonpoly scheme.pdb strand id: A

F,97
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2097
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2097
pdbx nonpoly scheme.pdb strand id: A

F,98
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2098
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2098
pdbx nonpoly scheme.pdb strand id: A

F,99
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2099
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2099
pdbx nonpoly scheme.pdb strand id: A

F,100
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2100
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2100
pdbx nonpoly scheme.pdb strand id: A

F,101
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2101
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2101
pdbx nonpoly scheme.pdb strand id: A

F,102
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2102
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2102
pdbx nonpoly scheme.pdb strand id: A

F,103
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2103
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2103
pdbx nonpoly scheme.pdb strand id: A

F,104
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2104
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2104
pdbx nonpoly scheme.pdb strand id: A

F,105
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2105
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2105
pdbx nonpoly scheme.pdb strand id: A

F,106
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2106
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2106
pdbx nonpoly scheme.pdb strand id: A

F,107
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2107
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2107
pdbx nonpoly scheme.pdb strand id: A

F,108
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2108
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2108
pdbx nonpoly scheme.pdb strand id: A

F,109
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2109
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2109
pdbx nonpoly scheme.pdb strand id: A

F,110
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2110
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2110
pdbx nonpoly scheme.pdb strand id: A

F,111
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2111
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2111
pdbx nonpoly scheme.pdb strand id: A

F,112
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2112
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2112
pdbx nonpoly scheme.pdb strand id: A

F,113
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2113
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2113
pdbx nonpoly scheme.pdb strand id: A

F,114
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2114
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2114
pdbx nonpoly scheme.pdb strand id: A

F,115
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2115
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2115
pdbx nonpoly scheme.pdb strand id: A

F,116
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2116
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2116
pdbx nonpoly scheme.pdb strand id: A

F,117
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2117
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2117
pdbx nonpoly scheme.pdb strand id: A

F,118
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2118
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2118
pdbx nonpoly scheme.pdb strand id: A

F,119
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2119
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2119
pdbx nonpoly scheme.pdb strand id: A

F,120
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2120
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2120
pdbx nonpoly scheme.pdb strand id: A

F,121
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2121
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2121
pdbx nonpoly scheme.pdb strand id: A

F,122
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2122
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2122
pdbx nonpoly scheme.pdb strand id: A

F,123
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2123
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2123
pdbx nonpoly scheme.pdb strand id: A

F,124
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 124
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2124
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2124
pdbx nonpoly scheme.pdb strand id: A

F,125
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 125
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2125
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2125
pdbx nonpoly scheme.pdb strand id: A

F,126
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 126
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2126
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2126
pdbx nonpoly scheme.pdb strand id: A

F,127
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 127
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2127
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2127
pdbx nonpoly scheme.pdb strand id: A

F,128
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 128
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2128
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2128
pdbx nonpoly scheme.pdb strand id: A

F,129
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 129
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2129
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2129
pdbx nonpoly scheme.pdb strand id: A

F,130
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 130
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2130
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2130
pdbx nonpoly scheme.pdb strand id: A

F,131
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 131
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2131
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2131
pdbx nonpoly scheme.pdb strand id: A

F,132
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 132
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2132
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2132
pdbx nonpoly scheme.pdb strand id: A

F,133
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 133
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2133
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2133
pdbx nonpoly scheme.pdb strand id: A

F,134
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 134
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2134
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2134
pdbx nonpoly scheme.pdb strand id: A

F,135
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 135
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2135
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2135
pdbx nonpoly scheme.pdb strand id: A

F,136
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 136
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2136
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2136
pdbx nonpoly scheme.pdb strand id: A

F,137
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 137
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2137
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2137
pdbx nonpoly scheme.pdb strand id: A

F,138
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 138
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2138
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2138
pdbx nonpoly scheme.pdb strand id: A

F,139
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 139
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2139
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2139
pdbx nonpoly scheme.pdb strand id: A

F,140
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 140
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2140
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2140
pdbx nonpoly scheme.pdb strand id: A

F,141
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 141
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2141
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2141
pdbx nonpoly scheme.pdb strand id: A

F,142
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 142
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2142
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2142
pdbx nonpoly scheme.pdb strand id: A

F,143
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 143
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2143
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2143
pdbx nonpoly scheme.pdb strand id: A

F,144
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 144
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2144
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2144
pdbx nonpoly scheme.pdb strand id: A

F,145
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 145
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2145
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2145
pdbx nonpoly scheme.pdb strand id: A

F,146
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 146
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2146
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2146
pdbx nonpoly scheme.pdb strand id: A

F,147
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 147
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2147
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2147
pdbx nonpoly scheme.pdb strand id: A

F,148
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 148
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2148
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2148
pdbx nonpoly scheme.pdb strand id: A

F,149
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 149
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2149
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2149
pdbx nonpoly scheme.pdb strand id: A

F,150
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 150
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2150
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2150
pdbx nonpoly scheme.pdb strand id: A

F,151
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 151
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2151
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2151
pdbx nonpoly scheme.pdb strand id: A

F,152
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 152
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2152
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2152
pdbx nonpoly scheme.pdb strand id: A

F,153
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 153
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2153
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2153
pdbx nonpoly scheme.pdb strand id: A

F,154
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 154
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2154
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2154
pdbx nonpoly scheme.pdb strand id: A

F,155
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 155
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2155
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2155
pdbx nonpoly scheme.pdb strand id: A

F,156
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 156
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2156
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2156
pdbx nonpoly scheme.pdb strand id: A

F,157
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 157
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2157
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2157
pdbx nonpoly scheme.pdb strand id: A

F,158
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 158
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2158
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2158
pdbx nonpoly scheme.pdb strand id: A

F,159
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 159
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2159
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2159
pdbx nonpoly scheme.pdb strand id: A

F,160
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 160
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2160
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2160
pdbx nonpoly scheme.pdb strand id: A

F,161
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 161
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2161
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2161
pdbx nonpoly scheme.pdb strand id: A

F,162
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 162
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2162
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2162
pdbx nonpoly scheme.pdb strand id: A

F,163
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 163
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2163
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2163
pdbx nonpoly scheme.pdb strand id: A

F,164
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 164
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2164
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2164
pdbx nonpoly scheme.pdb strand id: A

F,165
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 165
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2165
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2165
pdbx nonpoly scheme.pdb strand id: A

F,166
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 166
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2166
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2166
pdbx nonpoly scheme.pdb strand id: A

F,167
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 167
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2167
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2167
pdbx nonpoly scheme.pdb strand id: A

F,168
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 168
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2168
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2168
pdbx nonpoly scheme.pdb strand id: A

F,169
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 169
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2169
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2169
pdbx nonpoly scheme.pdb strand id: A

F,170
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 170
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2170
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2170
pdbx nonpoly scheme.pdb strand id: A

F,171
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 171
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2171
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2171
pdbx nonpoly scheme.pdb strand id: A

F,172
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 172
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2172
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2172
pdbx nonpoly scheme.pdb strand id: A

F,173
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 173
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2173
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2173
pdbx nonpoly scheme.pdb strand id: A

F,174
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 174
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2174
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2174
pdbx nonpoly scheme.pdb strand id: A

F,175
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 175
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2175
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2175
pdbx nonpoly scheme.pdb strand id: A

F,176
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 176
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2176
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2176
pdbx nonpoly scheme.pdb strand id: A

F,177
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 177
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2177
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2177
pdbx nonpoly scheme.pdb strand id: A

F,178
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 178
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2178
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2178
pdbx nonpoly scheme.pdb strand id: A

F,179
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 179
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2179
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2179
pdbx nonpoly scheme.pdb strand id: A

F,180
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 180
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2180
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2180
pdbx nonpoly scheme.pdb strand id: A

F,181
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 181
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2181
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2181
pdbx nonpoly scheme.pdb strand id: A

F,182
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 182
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2182
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2182
pdbx nonpoly scheme.pdb strand id: A

F,183
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 183
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2183
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2183
pdbx nonpoly scheme.pdb strand id: A

F,184
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 184
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2184
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2184
pdbx nonpoly scheme.pdb strand id: A

F,185
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 185
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2185
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2185
pdbx nonpoly scheme.pdb strand id: A

F,186
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 186
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2186
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2186
pdbx nonpoly scheme.pdb strand id: A

F,187
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 187
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2187
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2187
pdbx nonpoly scheme.pdb strand id: A

F,188
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 188
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2188
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2188
pdbx nonpoly scheme.pdb strand id: A

F,189
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 189
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2189
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2189
pdbx nonpoly scheme.pdb strand id: A

F,190
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 190
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2190
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2190
pdbx nonpoly scheme.pdb strand id: A

F,191
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 191
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2191
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2191
pdbx nonpoly scheme.pdb strand id: A

F,192
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 192
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2192
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2192
pdbx nonpoly scheme.pdb strand id: A

F,193
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 193
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2193
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2193
pdbx nonpoly scheme.pdb strand id: A

F,194
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 194
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2194
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2194
pdbx nonpoly scheme.pdb strand id: A

F,195
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 195
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2195
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2195
pdbx nonpoly scheme.pdb strand id: A

F,196
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 196
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2196
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2196
pdbx nonpoly scheme.pdb strand id: A

F,197
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 197
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2197
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2197
pdbx nonpoly scheme.pdb strand id: A

F,198
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 198
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2198
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2198
pdbx nonpoly scheme.pdb strand id: A

F,199
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 199
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2199
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2199
pdbx nonpoly scheme.pdb strand id: A

F,200
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 200
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2200
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2200
pdbx nonpoly scheme.pdb strand id: A

F,201
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 201
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2201
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2201
pdbx nonpoly scheme.pdb strand id: A

F,202
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 202
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2202
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2202
pdbx nonpoly scheme.pdb strand id: A

F,203
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 203
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2203
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2203
pdbx nonpoly scheme.pdb strand id: A

F,204
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 204
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2204
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2204
pdbx nonpoly scheme.pdb strand id: A

F,205
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 205
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2205
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2205
pdbx nonpoly scheme.pdb strand id: A

F,206
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 206
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2206
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2206
pdbx nonpoly scheme.pdb strand id: A

F,207
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 207
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2207
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2207
pdbx nonpoly scheme.pdb strand id: A

F,208
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 208
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2208
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2208
pdbx nonpoly scheme.pdb strand id: A

F,209
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 209
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2209
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2209
pdbx nonpoly scheme.pdb strand id: A

F,210
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 210
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2210
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2210
pdbx nonpoly scheme.pdb strand id: A

F,211
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 211
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2211
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2211
pdbx nonpoly scheme.pdb strand id: A

F,212
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 212
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2212
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2212
pdbx nonpoly scheme.pdb strand id: A

F,213
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 213
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2213
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2213
pdbx nonpoly scheme.pdb strand id: A

F,214
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 214
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2214
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2214
pdbx nonpoly scheme.pdb strand id: A

F,215
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 215
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2215
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2215
pdbx nonpoly scheme.pdb strand id: A

F,216
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 216
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2216
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2216
pdbx nonpoly scheme.pdb strand id: A

F,217
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 217
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2217
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2217
pdbx nonpoly scheme.pdb strand id: A

F,218
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 218
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2218
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2218
pdbx nonpoly scheme.pdb strand id: A

F,219
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 219
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2219
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2219
pdbx nonpoly scheme.pdb strand id: A

F,220
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 220
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2220
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2220
pdbx nonpoly scheme.pdb strand id: A

F,221
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 221
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2221
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2221
pdbx nonpoly scheme.pdb strand id: A

F,222
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 222
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2222
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2222
pdbx nonpoly scheme.pdb strand id: A

F,223
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 223
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2223
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2223
pdbx nonpoly scheme.pdb strand id: A

F,224
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 224
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2224
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2224
pdbx nonpoly scheme.pdb strand id: A

F,225
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 225
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2225
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2225
pdbx nonpoly scheme.pdb strand id: A

F,226
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 226
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2226
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2226
pdbx nonpoly scheme.pdb strand id: A

F,227
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 227
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2227
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2227
pdbx nonpoly scheme.pdb strand id: A

F,228
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 228
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2228
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2228
pdbx nonpoly scheme.pdb strand id: A

F,229
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 229
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2229
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2229
pdbx nonpoly scheme.pdb strand id: A

F,230
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 230
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2230
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2230
pdbx nonpoly scheme.pdb strand id: A

F,231
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 231
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2231
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2231
pdbx nonpoly scheme.pdb strand id: A

F,232
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 232
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2232
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2232
pdbx nonpoly scheme.pdb strand id: A

F,233
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 233
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2233
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2233
pdbx nonpoly scheme.pdb strand id: A

F,234
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 234
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2234
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2234
pdbx nonpoly scheme.pdb strand id: A

F,235
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 235
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2235
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2235
pdbx nonpoly scheme.pdb strand id: A

F,236
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 236
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2236
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2236
pdbx nonpoly scheme.pdb strand id: A

F,237
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 237
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2237
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2237
pdbx nonpoly scheme.pdb strand id: A

F,238
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 238
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2238
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2238
pdbx nonpoly scheme.pdb strand id: A

F,239
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 239
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2239
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2239
pdbx nonpoly scheme.pdb strand id: A

F,240
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 240
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2240
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2240
pdbx nonpoly scheme.pdb strand id: A

F,241
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 241
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2241
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2241
pdbx nonpoly scheme.pdb strand id: A

F,242
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 242
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2242
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2242
pdbx nonpoly scheme.pdb strand id: A

F,243
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 243
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2243
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2243
pdbx nonpoly scheme.pdb strand id: A

F,244
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 244
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2244
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2244
pdbx nonpoly scheme.pdb strand id: A

F,245
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 245
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2245
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2245
pdbx nonpoly scheme.pdb strand id: A

F,246
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 246
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2246
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2246
pdbx nonpoly scheme.pdb strand id: A

F,247
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 247
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2247
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2247
pdbx nonpoly scheme.pdb strand id: A

F,248
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 248
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2248
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2248
pdbx nonpoly scheme.pdb strand id: A

F,249
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 249
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2249
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2249
pdbx nonpoly scheme.pdb strand id: A

F,250
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 250
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2250
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2250
pdbx nonpoly scheme.pdb strand id: A

F,251
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 251
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2251
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2251
pdbx nonpoly scheme.pdb strand id: A

F,252
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 252
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2252
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2252
pdbx nonpoly scheme.pdb strand id: A

F,253
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 253
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2253
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2253
pdbx nonpoly scheme.pdb strand id: A

F,254
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 254
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2254
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2254
pdbx nonpoly scheme.pdb strand id: A

F,255
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 255
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2255
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2255
pdbx nonpoly scheme.pdb strand id: A

F,256
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 256
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2256
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2256
pdbx nonpoly scheme.pdb strand id: A

F,257
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 257
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2257
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2257
pdbx nonpoly scheme.pdb strand id: A

F,258
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 258
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2258
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2258
pdbx nonpoly scheme.pdb strand id: A

F,259
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 259
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2259
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2259
pdbx nonpoly scheme.pdb strand id: A

F,260
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 260
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2260
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2260
pdbx nonpoly scheme.pdb strand id: A

F,261
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 261
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2261
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2261
pdbx nonpoly scheme.pdb strand id: A

F,262
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 262
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2262
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2262
pdbx nonpoly scheme.pdb strand id: A

F,263
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 263
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2263
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2263
pdbx nonpoly scheme.pdb strand id: A

F,264
type: pdbx nonpoly scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 264
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2264
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2264
pdbx nonpoly scheme.pdb strand id: A

A,1,SER,1
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,SER,1
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 42
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 42
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
referenced by pdbx poly seq scheme: A,1,SER,1
referenced by pdbx poly seq scheme: A,1,MET,2
referenced by pdbx poly seq scheme: A,1,ASN,3
referenced by pdbx poly seq scheme: A,1,PRO,4
referenced by pdbx poly seq scheme: A,1,PRO,5
referenced by pdbx poly seq scheme: A,1,PRO,6
referenced by pdbx poly seq scheme: A,1,PRO,7
referenced by pdbx poly seq scheme: A,1,GLU,8
referenced by pdbx poly seq scheme: A,1,THR,9
referenced by pdbx poly seq scheme: A,1,SER,10
referenced by pdbx poly seq scheme: A,1,ASN,11
referenced by pdbx poly seq scheme: A,1,PRO,12
referenced by pdbx poly seq scheme: A,1,ASN,13
referenced by pdbx poly seq scheme: A,1,LYS,14
referenced by pdbx poly seq scheme: A,1,PRO,15
referenced by pdbx poly seq scheme: A,1,LYS,16
referenced by pdbx poly seq scheme: A,1,ARG,17
referenced by pdbx poly seq scheme: A,1,GLN,18
referenced by pdbx poly seq scheme: A,1,THR,19
referenced by pdbx poly seq scheme: A,1,ASN,20
referenced by pdbx poly seq scheme: A,1,GLN,21
referenced by pdbx poly seq scheme: A,1,LEU,22
referenced by pdbx poly seq scheme: A,1,GLN,23
referenced by pdbx poly seq scheme: A,1,TYR,24
referenced by pdbx poly seq scheme: A,1,LEU,25
referenced by pdbx poly seq scheme: A,1,LEU,26
referenced by pdbx poly seq scheme: A,1,ARG,27
referenced by pdbx poly seq scheme: A,1,VAL,28
referenced by pdbx poly seq scheme: A,1,VAL,29
referenced by pdbx poly seq scheme: A,1,LEU,30
referenced by pdbx poly seq scheme: A,1,LYS,31
referenced by pdbx poly seq scheme: A,1,THR,32
referenced by pdbx poly seq scheme: A,1,LEU,33
referenced by pdbx poly seq scheme: A,1,TRP,34
referenced by pdbx poly seq scheme: A,1,LYS,35
referenced by pdbx poly seq scheme: A,1,HIS,36
referenced by pdbx poly seq scheme: A,1,GLN,37
referenced by pdbx poly seq scheme: A,1,PHE,38
referenced by pdbx poly seq scheme: A,1,ALA,39
referenced by pdbx poly seq scheme: A,1,TRP,40
referenced by pdbx poly seq scheme: A,1,PRO,41
referenced by pdbx poly seq scheme: A,1,PHE,42
referenced by pdbx poly seq scheme: A,1,GLN,43
referenced by pdbx poly seq scheme: A,1,GLN,44
referenced by pdbx poly seq scheme: A,1,PRO,45
referenced by pdbx poly seq scheme: A,1,VAL,46
referenced by pdbx poly seq scheme: A,1,ASP,47
referenced by pdbx poly seq scheme: A,1,ALA,48
referenced by pdbx poly seq scheme: A,1,VAL,49
referenced by pdbx poly seq scheme: A,1,LYS,50
referenced by pdbx poly seq scheme: A,1,LEU,51
referenced by pdbx poly seq scheme: A,1,ASN,52
referenced by pdbx poly seq scheme: A,1,LEU,53
referenced by pdbx poly seq scheme: A,1,PRO,54
referenced by pdbx poly seq scheme: A,1,ASP,55
referenced by pdbx poly seq scheme: A,1,TYR,56
referenced by pdbx poly seq scheme: A,1,TYR,57
referenced by pdbx poly seq scheme: A,1,LYS,58
referenced by pdbx poly seq scheme: A,1,ILE,59
referenced by pdbx poly seq scheme: A,1,ILE,60
referenced by pdbx poly seq scheme: A,1,LYS,61
referenced by pdbx poly seq scheme: A,1,THR,62
referenced by pdbx poly seq scheme: A,1,PRO,63
referenced by pdbx poly seq scheme: A,1,MET,64
referenced by pdbx poly seq scheme: A,1,ASP,65
referenced by pdbx poly seq scheme: A,1,MET,66
referenced by pdbx poly seq scheme: A,1,GLY,67
referenced by pdbx poly seq scheme: A,1,THR,68
referenced by pdbx poly seq scheme: A,1,ILE,69
referenced by pdbx poly seq scheme: A,1,LYS,70
referenced by pdbx poly seq scheme: A,1,LYS,71
referenced by pdbx poly seq scheme: A,1,ARG,72
referenced by pdbx poly seq scheme: A,1,LEU,73
referenced by pdbx poly seq scheme: A,1,GLU,74
referenced by pdbx poly seq scheme: A,1,ASN,75
referenced by pdbx poly seq scheme: A,1,ASN,76
referenced by pdbx poly seq scheme: A,1,TYR,77
referenced by pdbx poly seq scheme: A,1,TYR,78
referenced by pdbx poly seq scheme: A,1,TRP,79
referenced by pdbx poly seq scheme: A,1,ASN,80

A,1,MET,2
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,MET,2
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 43
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 43
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,3
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,3
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 44
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 44
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,4
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,4
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 45
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 45
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,5
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,5
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 46
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 46
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,6
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,6
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 47
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 47
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,7
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,7
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 48
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 48
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,8
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,8
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 49
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 49
pdbx poly seq scheme.pdb strand id: A

A,1,THR,9
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,9
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 50
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 50
pdbx poly seq scheme.pdb strand id: A

A,1,SER,10
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,SER,10
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 51
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 51
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,11
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,11
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 52
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 52
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,12
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,12
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 53
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 53
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,13
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,13
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 54
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 54
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,14
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,14
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 55
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 55
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,15
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,15
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 56
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 56
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,16
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,16
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 57
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 57
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,17
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ARG,17
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 58
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 58
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,18
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,18
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 59
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 59
pdbx poly seq scheme.pdb strand id: A

A,1,THR,19
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,19
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 60
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 60
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,20
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,20
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 61
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 61
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,21
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,21
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 62
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 62
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,22
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,22
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 63
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 63
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,23
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,23
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 64
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 64
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,24
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,24
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 65
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 65
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,25
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,25
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 66
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 66
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,26
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,26
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 67
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 67
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,27
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ARG,27
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 68
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 68
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,28
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,VAL,28
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 69
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 69
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,29
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,VAL,29
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 70
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 70
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,30
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,30
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 71
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 71
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,31
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,31
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 72
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 72
pdbx poly seq scheme.pdb strand id: A

A,1,THR,32
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,32
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 73
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 73
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,33
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,33
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 74
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 74
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,34
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TRP,34
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 75
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 75
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,35
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,35
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 76
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 76
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,36
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,HIS,36
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 77
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 77
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,37
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,37
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 78
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 78
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,38
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PHE,38
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 79
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 79
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,39
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ALA,39
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 80
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 80
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,40
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TRP,40
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 81
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 81
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,41
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,41
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 82
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 82
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,42
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PHE,42
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 83
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 83
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,43
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,43
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 84
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 84
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,44
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,44
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 85
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 85
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,45
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,45
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 86
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 86
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,46
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,VAL,46
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 87
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 87
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,47
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,47
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 88
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 88
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,48
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ALA,48
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 89
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 89
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,49
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,VAL,49
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 90
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 90
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,50
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,50
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 91
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 91
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,51
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,51
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 92
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 92
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,52
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,52
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 93
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 93
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,53
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,53
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 94
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 94
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,54
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,54
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 95
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 95
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,55
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,55
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 96
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 96
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,56
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,56
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 97
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 97
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,57
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,57
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 98
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 98
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,58
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,58
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 99
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 99
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,59
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,59
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 100
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 100
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,60
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,60
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 101
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 101
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,61
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,61
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 102
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 102
pdbx poly seq scheme.pdb strand id: A

A,1,THR,62
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,62
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 103
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 103
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,63
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,63
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 104
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 104
pdbx poly seq scheme.pdb strand id: A

A,1,MET,64
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,MET,64
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 105
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 105
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,65
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,65
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 106
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 106
pdbx poly seq scheme.pdb strand id: A

A,1,MET,66
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,MET,66
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 107
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 107
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,67
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLY,67
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 108
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 108
pdbx poly seq scheme.pdb strand id: A

A,1,THR,68
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,68
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 109
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,69
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,69
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 110
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,70
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,70
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 111
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 111
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,71
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,71
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 112
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 112
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,72
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ARG,72
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 113
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 113
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,73
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,73
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 114
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 114
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,74
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,74
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 115
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 115
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,75
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,75
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 116
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 116
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,76
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,76
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 117
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 117
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,77
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,77
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 118
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 118
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,78
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,78
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 119
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 119
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,79
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TRP,79
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 120
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 120
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,80
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,80
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 121
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 121
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,81
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ALA,81
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 122
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 122
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,82
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,82
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 123
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 123
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,83
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,83
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 124
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 124
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,84
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,CYS,84
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 125
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 125
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,85
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,85
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 126
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 126
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,86
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,86
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 127
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 127
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,87
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,87
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 128
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 128
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,88
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PHE,88
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 129
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 129
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,89
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,89
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 130
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 130
pdbx poly seq scheme.pdb strand id: A

A,1,THR,90
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,90
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 131
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 131
pdbx poly seq scheme.pdb strand id: A

A,1,MET,91
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,MET,91
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 132
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 132
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,92
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PHE,92
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 133
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 133
pdbx poly seq scheme.pdb strand id: A

A,1,THR,93
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,93
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 134
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 134
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,94
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,94
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 135
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 135
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,95
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,CYS,95
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 136
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 136
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,96
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,96
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 137
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 137
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,97
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,97
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 138
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 138
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,98
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,TYR,98
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 139
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 139
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,99
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,99
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 140
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 140
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,100
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,100
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 141
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 141
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,101
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,101
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 142
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 142
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,102
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLY,102
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 143
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 143
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,103
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,103
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 144
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 144
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,104
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASP,104
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 145
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 145
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,105
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,105
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 146
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 146
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,106
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,VAL,106
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 147
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 147
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,107
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,107
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 148
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 148
pdbx poly seq scheme.pdb strand id: A

A,1,MET,108
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,MET,108
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 149
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 149
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,109
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ALA,109
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 150
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 150
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,110
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,110
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 151
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 151
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,111
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ALA,111
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 152
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 152
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,112
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,112
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 153
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 153
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,113
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,113
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 154
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 154
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,114
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,114
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 155
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 155
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,115
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,115
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 156
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 156
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,116
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PHE,116
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 157
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 157
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,117
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,117
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 158
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 158
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,118
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLN,118
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 159
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 159
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,119
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LYS,119
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 160
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 160
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,120
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ILE,120
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 161
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 161
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,121
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,ASN,121
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 162
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 162
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,122
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,122
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 163
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 163
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,123
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,LEU,123
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 164
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 164
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,124
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,PRO,124
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 165
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 165
pdbx poly seq scheme.pdb strand id: A

A,1,THR,125
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,THR,125
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 166
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 166
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,126
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,126
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 167
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 167
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,127
type: pdbx poly seq scheme
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity poly seq: 1,GLU,127
reference to struct asym: http://rdf.wwpdb.org/pdb/4UIY/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 168
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 168
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/4UIY/pdbx_refine_tls/1
type: pdbx refine tls
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx refine tls.id: 1
pdbx refine tls.l11: 0.0475
pdbx refine tls.l12: 0.1324
pdbx refine tls.l13: -0.0457
pdbx refine tls.l22: 0.3829
pdbx refine tls.l23: -0.1323
pdbx refine tls.l33: 0.2511
pdbx refine tls.s11: -0.0044
pdbx refine tls.s12: 0.0067
pdbx refine tls.s13: -0.0013
pdbx refine tls.s21: -0.0009
pdbx refine tls.s22: 0.027
pdbx refine tls.s23: -0.0095
pdbx refine tls.s31: 0.0347
pdbx refine tls.s32: -0.0254
pdbx refine tls.s33: -0.0226
pdbx refine tls.t11: 0.0163
pdbx refine tls.t12: 0.0044
pdbx refine tls.t13: -0.0031
pdbx refine tls.t22: 0.009
pdbx refine tls.t23: -0.0008
pdbx refine tls.t33: 0.0106
pdbx refine tls.method: refined
pdbx refine tls.origin x: 25.5943
pdbx refine tls.origin y: 40.655
pdbx refine tls.origin z: 8.9448
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/4UIY/pdbx_refine_tls_group/1

http://rdf.wwpdb.org/pdb/4UIY/pdbx_refine_tls_group/1
type: pdbx refine tls group
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/4UIY/pdbx_refine_tls/1
pdbx refine tls group.id: 1
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: 42
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 168
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 1

http://rdf.wwpdb.org/pdb/4UIY/pdbx_struct_assembly/1
type: pdbx struct assembly
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx struct assembly.id: 1
pdbx struct assembly.details: author_and_software_defined_assembly
pdbx struct assembly.method details: PISA
pdbx struct assembly.oligomeric count: 1
pdbx struct assembly.oligomeric details: monomeric
referenced by pdbx struct assembly gen: 1,A,B,C,D,E,F,1

1,A,B,C,D,E,F,1
type: pdbx struct assembly gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/4UIY/pdbx_struct_assembly/1
pdbx struct assembly gen.assembly id: 1
pdbx struct assembly gen.asym id list: A,B,C,D,E,F
pdbx struct assembly gen.oper expression: 1

http://rdf.wwpdb.org/pdb/4UIY/pdbx_struct_oper_list/1
type: pdbx struct oper list
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx struct oper list.id: 1
pdbx struct oper list.matrix11: 1
pdbx struct oper list.matrix12: 0
pdbx struct oper list.matrix13: 0
pdbx struct oper list.matrix21: 0
pdbx struct oper list.matrix22: 1
pdbx struct oper list.matrix23: 0
pdbx struct oper list.matrix31: 0
pdbx struct oper list.matrix32: 0
pdbx struct oper list.matrix33: 1
pdbx struct oper list.name: 1_555
pdbx struct oper list.symmetry operation: x,y,z
pdbx struct oper list.type: identity operation
pdbx struct oper list.vector1: 0
pdbx struct oper list.vector2: 0
pdbx struct oper list.vector3: 0

http://rdf.wwpdb.org/pdb/4UIY/pdbx_validate_close_contact/1
type: pdbx validate close contact
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx validate close contact.id: 1
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HOH
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 2008
pdbx validate close contact.auth seq id 2: 2009
pdbx validate close contact.dist: 2.12

http://rdf.wwpdb.org/pdb/4UIY/pdbx_validate_rmsd_angle/1
type: pdbx validate rmsd angle
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx validate rmsd angle.id: 1
pdbx validate rmsd angle.pdb model num: 1
pdbx validate rmsd angle.angle deviation: -3.11
pdbx validate rmsd angle.angle standard deviation: 0.5
pdbx validate rmsd angle.angle target value: 120.3
pdbx validate rmsd angle.angle value: 117.19
pdbx validate rmsd angle.auth asym id 1: A
pdbx validate rmsd angle.auth asym id 2: A
pdbx validate rmsd angle.auth asym id 3: A
pdbx validate rmsd angle.auth atom id 1: NE
pdbx validate rmsd angle.auth atom id 2: CZ
pdbx validate rmsd angle.auth atom id 3: NH2
pdbx validate rmsd angle.auth comp id 1: ARG
pdbx validate rmsd angle.auth comp id 2: ARG
pdbx validate rmsd angle.auth comp id 3: ARG
pdbx validate rmsd angle.auth seq id 1: 113
pdbx validate rmsd angle.auth seq id 2: 113
pdbx validate rmsd angle.auth seq id 3: 113
pdbx validate rmsd angle.linker flag: N

http://rdf.wwpdb.org/pdb/4UIY/pdbx_validate_torsion/1
type: pdbx validate torsion
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
pdbx validate torsion.id: 1
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASN
pdbx validate torsion.auth seq id: 52
pdbx validate torsion.phi: -163.35
pdbx validate torsion.psi: 97.66

4UIY,X-RAY DIFFRACTION
type: refine
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
refine.entry id: 4UIY
refine.pdbx refine id: X-RAY DIFFRACTION
refine.b iso mean: 15.538
refine.aniso B11: 0.52
refine.aniso B12: 0
refine.aniso B13: 0
refine.aniso B22: -0.26
refine.aniso B23: 0
refine.aniso B33: -0.26
refine.correlation coeff fo to fc: 0.974
refine.correlation coeff fo to fc free: 0.964
refine.details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
refine.ls r factor r free: 0.1847
refine.ls r factor r work: 0.15643
refine.ls r factor obs: 0.15781
refine.ls d res high: 1.3
refine.ls d res low: 39.32
refine.ls number reflns r free: 1587
refine.ls number reflns obs: 29935
refine.ls percent reflns r free: 5
refine.ls percent reflns obs: 96.06
refine.overall SU b: 1.393
refine.overall SU ML: 0.031
refine.pdbx r free selection details: RANDOM
refine.pdbx diffrn id: 1
refine.pdbx ls cross valid method: THROUGHOUT
refine.pdbx method to determine struct: MOLECULAR REPLACEMENT
refine.pdbx overall ESU r: 0.051
refine.pdbx overall ESU r free: 0.054
refine.pdbx solvent ion probe radii: 0.8
refine.pdbx solvent shrinkage radii: 0.8
refine.pdbx solvent vdw probe radii: 1.2
refine.pdbx stereochemistry target values: MAXIMUM LIKELIHOOD
refine.solvent model details: BABINET MODEL WITH MASK

LAST,X-RAY DIFFRACTION
type: refine hist
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine hist.cycle id: LAST
refine hist.pdbx refine id: X-RAY DIFFRACTION
refine hist.d res high: 1.3
refine hist.d res low: 39.32
refine hist.number atoms solvent: 264
refine hist.number atoms total: 1370
refine hist.pdbx number atoms ligand: 44
refine hist.pdbx number atoms nucleic acid: 0
refine hist.pdbx number atoms protein: 1062

X-RAY DIFFRACTION,r bond refined d
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_refined_d
refine ls restr.dev ideal: 0.014
refine ls restr.dev ideal target: 0.019
refine ls restr.number: 1185

X-RAY DIFFRACTION,r bond other d
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_other_d
refine ls restr.dev ideal: 0.001
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 809

X-RAY DIFFRACTION,r angle refined deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_refined_deg
refine ls restr.dev ideal: 1.619
refine ls restr.dev ideal target: 1.937
refine ls restr.number: 1623

X-RAY DIFFRACTION,r angle other deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_other_deg
refine ls restr.dev ideal: 0.943
refine ls restr.dev ideal target: 3
refine ls restr.number: 1984

X-RAY DIFFRACTION,r dihedral angle 1 deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_1_deg
refine ls restr.dev ideal: 5.015
refine ls restr.dev ideal target: 5
refine ls restr.number: 130

X-RAY DIFFRACTION,r dihedral angle 2 deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_2_deg
refine ls restr.dev ideal: 37.463
refine ls restr.dev ideal target: 26
refine ls restr.number: 55

X-RAY DIFFRACTION,r dihedral angle 3 deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_3_deg
refine ls restr.dev ideal: 12.469
refine ls restr.dev ideal target: 15
refine ls restr.number: 199

X-RAY DIFFRACTION,r dihedral angle 4 deg
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_4_deg
refine ls restr.dev ideal: 8.773
refine ls restr.dev ideal target: 15
refine ls restr.number: 3

X-RAY DIFFRACTION,r chiral restr
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_chiral_restr
refine ls restr.dev ideal: 0.095
refine ls restr.dev ideal target: 0.2
refine ls restr.number: 163

X-RAY DIFFRACTION,r gen planes refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_refined
refine ls restr.dev ideal: 0.07
refine ls restr.dev ideal target: 0.021
refine ls restr.number: 1267

X-RAY DIFFRACTION,r gen planes other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_other
refine ls restr.dev ideal: 0.002
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 218

X-RAY DIFFRACTION,r nbd refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_refined

X-RAY DIFFRACTION,r nbd other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_other

X-RAY DIFFRACTION,r nbtor refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_refined

X-RAY DIFFRACTION,r nbtor other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_other

X-RAY DIFFRACTION,r xyhbond nbd refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_refined

X-RAY DIFFRACTION,r xyhbond nbd other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_other

X-RAY DIFFRACTION,r metal ion refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_refined

X-RAY DIFFRACTION,r metal ion other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_other

X-RAY DIFFRACTION,r symmetry vdw refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_refined

X-RAY DIFFRACTION,r symmetry vdw other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_other

X-RAY DIFFRACTION,r symmetry hbond refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_refined

X-RAY DIFFRACTION,r symmetry hbond other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_other

X-RAY DIFFRACTION,r symmetry metal ion refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_refined

X-RAY DIFFRACTION,r symmetry metal ion other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_other

X-RAY DIFFRACTION,r mcbond it
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_it

X-RAY DIFFRACTION,r mcbond other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_other

X-RAY DIFFRACTION,r mcangle it
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_it

X-RAY DIFFRACTION,r mcangle other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_other

X-RAY DIFFRACTION,r scbond it
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_it

X-RAY DIFFRACTION,r scbond other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_other

X-RAY DIFFRACTION,r scangle it
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_it

X-RAY DIFFRACTION,r scangle other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_other

X-RAY DIFFRACTION,r long range B refined
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_refined

X-RAY DIFFRACTION,r long range B other
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_other

X-RAY DIFFRACTION,r rigid bond restr
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_rigid_bond_restr

X-RAY DIFFRACTION,r sphericity free
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_free

X-RAY DIFFRACTION,r sphericity bonded
type: refine ls restr
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_bonded

1.3,X-RAY DIFFRACTION
type: refine ls shell
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
refine ls shell.d res high: 1.3
refine ls shell.pdbx refine id: X-RAY DIFFRACTION
refine ls shell.r factor r free: 0.225
refine ls shell.r factor r work: 0.2
refine ls shell.d res low: 1.334
refine ls shell.number reflns r free: 89
refine ls shell.number reflns r work: 1696
refine ls shell.pdbx total number of bins used: 20
refine ls shell.percent reflns obs: 76.84

http://rdf.wwpdb.org/pdb/4UIY/reflns/1
type: reflns
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
reflns.pdbx ordinal: 1
reflns.d resolution high: 1.3
reflns.d resolution low: 39.32
reflns.entry id: 4UIY
reflns.number obs: 31523
reflns.observed criterion sigma i: 2
reflns.pdbx rmerge i obs: 0.05
reflns.pdbx diffrn id: 1
reflns.pdbx net i over sigma i: 16.5
reflns.pdbx redundancy: 5
reflns.percent possible obs: 96.6

http://rdf.wwpdb.org/pdb/4UIY/reflns_shell/1
type: reflns shell
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reflns shell.pdbx ordinal: 1
reflns shell.rmerge i obs: 0.24
reflns shell.d res high: 1.3
reflns shell.d res low: 1.37
reflns shell.mean i over sig i obs: 5.1
reflns shell.pdbx diffrn id: 1
reflns shell.pdbx redundancy: 4.1
reflns shell.percent possible all: 86.5

http://rdf.wwpdb.org/pdb/4UIY/software/1
type: software
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
software.pdbx ordinal: 1
software.classification: refinement
software.name: REFMAC
software.version: 5.6.0117

http://rdf.wwpdb.org/pdb/4UIY/software/2
type: software
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
software.pdbx ordinal: 2
software.classification: data reduction
software.name: XDS

http://rdf.wwpdb.org/pdb/4UIY/software/3
type: software
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
software.pdbx ordinal: 3
software.classification: data scaling
software.name: SCALA

4UIY
type: struct
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
struct.entry id: 4UIY
struct.pdbx descriptor: BROMODOMAIN-CONTAINING PROTEIN 4
struct.title: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/B
type: struct asym
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/2
struct asym.id: B
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/C
type: struct asym
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/2
struct asym.id: C
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/D
type: struct asym
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/2
struct asym.id: D
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/E
type: struct asym
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/3
struct asym.id: E
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4UIY/struct_asym/F
type: struct asym
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/4
struct asym.id: F
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

HELX P1
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P1
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 60
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 19
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 69
struct conf.end label asym id: A
struct conf.end label comp id: VAL
struct conf.end label seq id: 28
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 1
struct conf.pdbx PDB helix length: 10

HELX P
referenced by struct conf: HELX P1
referenced by struct conf: HELX P2
referenced by struct conf: HELX P3
referenced by struct conf: HELX P4
referenced by struct conf: HELX P5
referenced by struct conf: HELX P6
referenced by struct conf: HELX P7
type: struct conf type
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
struct conf type.id: HELX_P

HELX P2
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P2
struct conf.beg auth asym id: A
struct conf.beg auth comp id: VAL
struct conf.beg auth seq id: 69
struct conf.beg label asym id: A
struct conf.beg label comp id: VAL
struct conf.beg label seq id: 28
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 76
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 35
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 2
struct conf.pdbx PDB helix length: 8

HELX P3
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P3
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 80
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 39
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 84
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 43
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 3
struct conf.pdbx PDB helix length: 5

HELX P4
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P4
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 96
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 55
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ILE
struct conf.end auth seq id: 101
struct conf.end label asym id: A
struct conf.end label comp id: ILE
struct conf.end label seq id: 60
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 4
struct conf.pdbx PDB helix length: 6

HELX P5
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P5
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 106
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 65
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 116
struct conf.end label asym id: A
struct conf.end label comp id: ASN
struct conf.end label seq id: 75
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 5
struct conf.pdbx PDB helix length: 11

HELX P6
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P6
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 121
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 80
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 140
struct conf.end label asym id: A
struct conf.end label comp id: ASN
struct conf.end label seq id: 99
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 6
struct conf.pdbx PDB helix length: 20

HELX P7
type: struct conf
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct conf type: HELX P
struct conf.id: HELX_P7
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 144
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 103
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLU
struct conf.end auth seq id: 163
struct conf.end label asym id: A
struct conf.end label comp id: GLU
struct conf.end label seq id: 122
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 7
struct conf.pdbx PDB helix length: 20

4UIY
type: struct keywords
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
struct keywords.entry id: 4UIY
struct keywords.pdbx keywords: TRANSCRIPTION
struct keywords.text: TRANSCRIPTION, INHIBITOR, HISTONE, EPIGENETIC READER, BROMODOMAIN, BRD4, BROMODOMAIN CONTAINING PROTEIN 4, ANTAGONIST

http://rdf.wwpdb.org/pdb/4UIY/struct_ref/1
type: struct ref
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entity: http://rdf.wwpdb.org/pdb/4UIY/entity/1
struct ref.id: 1
struct ref.db code: BRD4_HUMAN
struct ref.db name: UNP
struct ref.entity id: 1
struct ref.pdbx db accession: O60885
link to uniprot: uniprot:O60885
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq/1

uniprot:O60885

http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq/1
type: struct ref seq
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct ref: http://rdf.wwpdb.org/pdb/4UIY/struct_ref/1
struct ref seq.align id: 1
struct ref seq.db align beg: 44
struct ref seq.db align end: 168
struct ref seq.pdbx PDB id code: 4UIY
struct ref seq.pdbx auth seq align beg: 44
struct ref seq.pdbx auth seq align end: 168
struct ref seq.pdbx db accession: O60885
struct ref seq.pdbx strand id: A
struct ref seq.ref id: 1
struct ref seq.seq align beg: 3
struct ref seq.seq align end: 127
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq_dif/2
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq_dif/1

http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq_dif/1
type: struct ref seq dif
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 1
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 42
struct ref seq dif.pdbx pdb id code: 4UIY
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: O60885
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq_dif/2
type: struct ref seq dif
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4UIY/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 2
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: MET
struct ref seq dif.pdbx auth seq num: 43
struct ref seq dif.pdbx pdb id code: 4UIY
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: O60885
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

AC1
type: struct site
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
struct site.id: AC1
struct site.details: BINDING SITE FOR RESIDUE EDO A 1169
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 6
referenced by struct site gen: 6,AC1
referenced by struct site gen: 1,AC1
referenced by struct site gen: 2,AC1
referenced by struct site gen: 3,AC1
referenced by struct site gen: 4,AC1
referenced by struct site gen: 5,AC1

AC2
type: struct site
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
struct site.id: AC2
struct site.details: BINDING SITE FOR RESIDUE EDO A 1170
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 7
referenced by struct site gen: 13,AC2
referenced by struct site gen: 7,AC2
referenced by struct site gen: 8,AC2
referenced by struct site gen: 9,AC2
referenced by struct site gen: 10,AC2
referenced by struct site gen: 11,AC2
referenced by struct site gen: 12,AC2

AC3
type: struct site
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
struct site.id: AC3
struct site.details: BINDING SITE FOR RESIDUE EDO A 1171
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 6
referenced by struct site gen: 19,AC3
referenced by struct site gen: 14,AC3
referenced by struct site gen: 15,AC3
referenced by struct site gen: 16,AC3
referenced by struct site gen: 17,AC3
referenced by struct site gen: 18,AC3

AC4
type: struct site
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
struct site.id: AC4
struct site.details: BINDING SITE FOR RESIDUE 5V2 A 1172
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 16
referenced by struct site gen: 35,AC4
referenced by struct site gen: 20,AC4
referenced by struct site gen: 21,AC4
referenced by struct site gen: 22,AC4
referenced by struct site gen: 23,AC4
referenced by struct site gen: 24,AC4
referenced by struct site gen: 25,AC4
referenced by struct site gen: 26,AC4
referenced by struct site gen: 27,AC4
referenced by struct site gen: 28,AC4
referenced by struct site gen: 29,AC4
referenced by struct site gen: 30,AC4
referenced by struct site gen: 31,AC4
referenced by struct site gen: 32,AC4
referenced by struct site gen: 33,AC4
referenced by struct site gen: 34,AC4

1,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 1
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ILE
struct site gen.auth seq id: 100
struct site gen.label asym id: A
struct site gen.label comp id: ILE
struct site gen.label seq id: 59
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

2,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 2
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ILE
struct site gen.auth seq id: 101
struct site gen.label asym id: A
struct site gen.label comp id: ILE
struct site gen.label seq id: 60
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

3,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 3
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 102
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 61
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

4,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 4
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: THR
struct site gen.auth seq id: 103
struct site gen.label asym id: A
struct site gen.label comp id: THR
struct site gen.label seq id: 62
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

5,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 5
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ASN
struct site gen.auth seq id: 135
struct site gen.label asym id: A
struct site gen.label comp id: ASN
struct site gen.label seq id: 94
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

6,AC1
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC1
struct site gen.id: 6
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2169
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

7,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 7
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: TRP
struct site gen.auth seq id: 81
struct site gen.label asym id: A
struct site gen.label comp id: TRP
struct site gen.label seq id: 40
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

8,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 8
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 85
struct site gen.label asym id: A
struct site gen.label comp id: GLN
struct site gen.label seq id: 44
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

9,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 9
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: ASP
struct site gen.auth seq id: 96
struct site gen.label asym id: A
struct site gen.label comp id: ASP
struct site gen.label seq id: 55
struct site gen.pdbx num res: 7
struct site gen.symmetry: 4_575

10,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 10
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: 5V2
struct site gen.auth seq id: 1172
struct site gen.label asym id: E
struct site gen.label comp id: 5V2
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

11,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 11
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2144
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

12,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 12
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2261
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

13,AC2
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC2
struct site gen.id: 13
struct site gen.site id: AC2
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2262
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 7
struct site gen.symmetry: 1_555

14,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 14
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: PRO
struct site gen.auth seq id: 53
struct site gen.label asym id: A
struct site gen.label comp id: PRO
struct site gen.label seq id: 12
struct site gen.pdbx num res: 6
struct site gen.symmetry: 2_674

15,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 15
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 99
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 58
struct site gen.pdbx num res: 6
struct site gen.symmetry: 4_575

16,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 16
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: MET
struct site gen.auth seq id: 149
struct site gen.label asym id: A
struct site gen.label comp id: MET
struct site gen.label seq id: 108
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

17,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 17
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: 5V2
struct site gen.auth seq id: 1172
struct site gen.label asym id: E
struct site gen.label comp id: 5V2
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

18,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 18
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2224
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

19,AC3
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC3
struct site gen.id: 19
struct site gen.site id: AC3
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2263
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 6
struct site gen.symmetry: 1_555

20,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 20
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: TRP
struct site gen.auth seq id: 81
struct site gen.label asym id: A
struct site gen.label comp id: TRP
struct site gen.label seq id: 40
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

21,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 21
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: PRO
struct site gen.auth seq id: 82
struct site gen.label asym id: A
struct site gen.label comp id: PRO
struct site gen.label seq id: 41
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

22,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 22
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: VAL
struct site gen.auth seq id: 87
struct site gen.label asym id: A
struct site gen.label comp id: VAL
struct site gen.label seq id: 46
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

23,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 23
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 92
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 51
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

24,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 24
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 94
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 53
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

25,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 25
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ASP
struct site gen.auth seq id: 96
struct site gen.label asym id: A
struct site gen.label comp id: ASP
struct site gen.label seq id: 55
struct site gen.pdbx num res: 16
struct site gen.symmetry: 4_575

26,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 26
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 99
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 58
struct site gen.pdbx num res: 16
struct site gen.symmetry: 4_575

27,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 27
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: TYR
struct site gen.auth seq id: 139
struct site gen.label asym id: A
struct site gen.label comp id: TYR
struct site gen.label seq id: 98
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

28,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 28
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ASN
struct site gen.auth seq id: 140
struct site gen.label asym id: A
struct site gen.label comp id: ASN
struct site gen.label seq id: 99
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

29,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 29
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: LYS
struct site gen.auth seq id: 141
struct site gen.label asym id: A
struct site gen.label comp id: LYS
struct site gen.label seq id: 100
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

30,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 30
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: ASP
struct site gen.auth seq id: 144
struct site gen.label asym id: A
struct site gen.label comp id: ASP
struct site gen.label seq id: 103
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

31,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 31
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: EDO
struct site gen.auth seq id: 1170
struct site gen.label asym id: C
struct site gen.label comp id: EDO
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

32,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 32
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: EDO
struct site gen.auth seq id: 1171
struct site gen.label asym id: D
struct site gen.label comp id: EDO
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

33,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 33
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2147
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

34,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 34
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2159
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

35,AC4
type: struct site gen
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to struct site: AC4
struct site gen.id: 35
struct site gen.site id: AC4
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2264
struct site gen.label asym id: F
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

4UIY
type: symmetry
of datablock: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide
reference to entry: 4UIY
symmetry.entry id: 4UIY
symmetry.int tables number: 19
symmetry.space group name H-M: P 21 21 21