Structure of wild-type HIV protease in complex with photosensitive inhibitor PDI-6

Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor.

PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGIGGFIKVRQYDQIIIEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF

Ministry of Education of the CzechRepublic

Ministry of Education, Youth and Sports of the Czech Republic

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

The biological assembly is a dimer. There is one biological unit in the asymetric unit

HIV-1, viral protease, aspartic protease, inhibition, hydrolase

PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF