N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p variant Q93E F145W (NN27)

SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.

Structural basis of the 9-fold symmetry of centrioles.

GSMPLLLDDGDPKAQTGFDLSTATTLFWRPVPVHVKQQDREDVLEELTFRILTGVAKQNHNLRILRIHISSDSDLFFLHT
LEVSEEDFQSLKNDEGILVDFASFPGKIISLLEKCILAQPGDSPRFQAVLTIRGGESVFKIVEINDWKQLPHITLAFRPG
N

homodimer, stabilization, mutation, centriole, SAS-6, cartwheel, structural protein, beta-sandwich, alpha-beta protein, centriolar

MPLLLDDGDPKAQTGFDLSTATTLFWRPVPVHVKQQDREDVLEELTFRILTGVAKQNHNLRILRIHISSDSDLFFLHTLE
VSEEDFQSLKNDQGILVDFASFPGKIISLLEKCILAQPGDSPRFQAVLTIRGGESVFKIVEINDFKQLPHITLAFRPGN