Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase V349A mutant (ISOA-ECI2)

Human Delta (3) , Delta (2) -enoyl-CoA isomerase, type 2: a structural enzymology study on the catalytic role of its ACBP domain and helix-10.

DRS-1,Delta(3),delta(2)-enoyl-CoA isomerase,D3,D2-enoyl-CoA isomerase,Diazepam-binding inhibitor-related protein 1,DBI-related protein 1,Dodecenoyl-CoA isomerase,Hepatocellular carcinoma-associated antigen 88,Peroxisomal 3,2-trans-enoyl-CoA isomerase,pECI,Renal carcinoma antigen NY-REN-1

MHHHHHHSSGVDLGTENLYFQSMGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGD
YYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSH
LGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRK
REREKLHAVNAEECNVLQGRWLSDECTNAAVNFLSR

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

PECI, enoy-CoA isomerase, crotonase, beta-oxidation, isomerase

GFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKA
KNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKAT
EMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRKREREKLHAVNAEECNVLQGRWLS
DECTNAVVNFLSR