Structure of the MSL2 CXC domain bound with a specific MRE sequence

Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.

DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3')

DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3')

0.1M HEPES-Na (pH 7.5), 10% PEG 3350 (w/v), 0.2M proline, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Zinc cluster, DNA binding domain, Dosage compensation, DNA binding protein-DNA complex