Crystal structure of a putative carveol dehydrogenase from Mycobacterium avium bound to NAD

Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.

GPGSMLRAANLDRSPEEYGMGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARL
VEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDIMLIGVWNTFQVAIPHM
KERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIE
ENPHLVNAMSTALPDFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVKR

MyavA.01326.g.A1 PS01550 at 20 mg/mL with 2.5 mM NAD against MCSG1 condition C12, 0.1 M BisTrisHCL pH 6.5, 25% PEG 3350 supplemented with 15% EG as cryo-protectant, crystal tracking ID 257485c12, VAPOR DIFFUSION, SITTING DROP, temperature 289K

Seattle Structural Genomics Center for Infectious Disease
NIAID, National Institute of Allergy and Infectious Diseases

U VALUES : WITH TLS ADDED HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Seattle Structural Genomics Center for Infectious Disease, SSGCID, putative non-exchangeable NAD, oxidoreductase

MRAANLDRSPEEYGMGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVEKTG
QEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGLDIMLIGVWNTFQVAIPHMKERGQ
GGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHL
VNAMSTALPDFPMIEPRDVSNAILFLISDAGRSFTGSVLKVDAGMDVKR