Crystal Structure of an Inositol hexakisphosphate kinase apo-EhIP6KA

IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family.

GSFTAGGHGGPQQLHPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRP
FVLDLKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFND
GKKYRKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNN
LKSILEDIENEFKSL

8% (w/v) PEG 3350, 100 mM Na3Citrate, pH 5.2 at 25C, Micro Seeding, temperature 298K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

PDKG kinase, Inositol Phosphate, TRANSFERASE

AGGHGGPQQLHPDGQYLLKPCLSHRERDFYLHIKDDKEWTGTGIIPKFYGVELHEFGFGELEFIRMENLMYKYKRPFVLD
LKIGTQTWDPETASSKMKKRLVVDSTSTTTSLGVRFSGMERNIGEEKPILYSRYLCTHEVNTRDSLKEYIKLFFNDGKKY
RKELVPYFISQLDKMIEVMKKREYKMFSSSVLFVYDSTTTLEDKKYNCKMIDFAHNWILSEEECTVEDGFLFGLNNLKSI
LEDIENEFKSL