Structure of Rabphilin C2A domain bound to IP3
Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
DQATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHG ITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVI
25-28% PEG 4K, 10-20mM Ammonium sulfate, 100mM HEPES pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K
CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A
STRUCTURAL DETERMINANTS FOR CA2+ AND PIP2 BINDING BY THE C2A DOMAIN OF RABPHILIN-3A
CRYSTAL STRUCTURE OF THE C2B DOMAIN OF RABPHILIN
CRYSTAL STRUCTURE OF THE C2B DOMAIN OF RABPHILIN 3A
RABPHILIN-3A, C2 DOMAIN, C2A, CALCIUM BINDING, SYNAPTIC EXOCYTOSIS METAL-BINDING, PROTEIN TRANSPORT, C-2 domain fold, EXOPHILIN-1