A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture

Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.

GPLGSDSKIEKMLPDGGRLVVFPNGTRKELSADGQTVKVMFFNGDVKHTMPDQRVIYYYAEAQTTHITYPDGMEVLQFPN
NQTEKHFPDGRKEITFPDQTVKTLHPDGREESVLTDGTIIQLNPDGSKVIQFNTGQREIHTADFKRREYPDGTVKTVYSD
GRQETQYPTGRVRLKDPQGKVIMD

G-box, beta-sheet, Centriole organisation, structural protein, protein binding

SDSKIEKMLPDGGRLVVFPNGTRKELSADGQTVKVMFFNGDVKHTMPDQRVIYYYAEAQTTHITYPDGMEVLQFPNNQTE
KHFPDGRKEITFPDQTVKTLHPDGREESVLTDGTIIQLNPDGSKVIQFNTGQREIHTADFKRREYPDGTVKTVYSDGRQE
TQYPTGRVRLKDPQGKVIMD

BINDING SITE FOR CHAIN B OF SCL-INTERRUPTING LOCUS PROTEIN HOMOLOG