Structure of mrna stem-loop, human stem-loop binding protein and 3'hexo ternary complex

Structure of Histone Mrna Stem-Loop, Human Stem-Loop Binding Protein, and 3'Hexo Ternary Complex.

SAP DOMAIN AND NUCLEASE DOMAIN, UNP residues 55-349

RNA-BINDING DOMAIN, UNP residues 125-223

3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, HEXO

TSSASDFSDPVYKEIAITNGCINR(MSE)SKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKL(MSE)LKESNFADSY
YDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQV
LKKVIDW(MSE)KLKELGTKYKYSLLTDGSWD(MSE)SKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLT
I(MSE)LEKLG(MSE)DYDGRPHCGLDDSKNIARIAVR(MSE)LQDGCELRINEK(MSE)HAGQL(MSE)SVSSSLPIEG
TPPPQ(MSE)PHFRKLEHHHHHH

TSSASDFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIID
FEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWM
KLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHC
GLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRKLEHHHHHH

MGSSHHHHHHSSGLVPRGSHMPADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSW
DQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSE

8% (W/V) TACSIMATE (PH 6.0), 18% (W/V) PEG3350, MACROSEEDING, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 293K, VAPOR DIFFUSION, HANGING DROP

RNA-RNA BINDING PROTEIN-HYDROLASE COMPLEX, HISTONE MRNA 3'-END PROCESSING, HISTONE MRNA TRANSLATION, MICRORNA HOMEOSTASIS, 5.8S RRNA 3 -END MATURATION, ZFP100, LSM11, NUCLEUS

TSSASDFSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKESNFADSYYDYICIID
FEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCISLTGITQDQVDRADTFPQVLKKVIDWM
KLKELGTKYKYSLLTDGSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHC
GLDDSKNIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK

PADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEG
CDLQEIHPVDLESAESSSE