Crystal structure of the Ig-like D1 domain from mouse Carcinoembryogenic antigen-related cell adhesion molecule 15 (CEACAM15) [PSI-NYSGRC-005691]

New York Structural Genomics Research Consortium (NYSGRC)

Atoms-to-Animals: The Immune Function Network (IFN)

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Crystal structure of the Ig-like D1 domain of CEACAM15 from Mus musculus [NYSGRC-005691]

Carcinoembryonic antigen-related cell adhesion molecule 15

QDYGGTAALLTSKEMRFSAAEGAKVLLSVPDQEENLLSFSWYKGKDVNENFTIAHYKKSSDSLQLGKKVSGREEIYKDGS
MMLRAITLEDTGFYTLQTFKAHGQQEVTHVHLQVYKIVTKAENLYF

Unknown polpypeptides, probably arising from cloning artifacts at the N and/or C-terminus.

Protein (20 mM Hepes, pH 7.5, 150 mM NaCl, 10% glycerol; Reservoir (0.2M Sodium Chloride, 0.1M Sodium Citrate:Citric Acid (pH 5.5), 40%(v/v) 1,2-Propanediol); Cryoprotection (Reservoir + final concentration of 20%(v/v) DMSO), Sitting Drop Vapor Diffusion, temperature 298K

New York Structural Genomics Research Consortium

Atoms-to-Animals: The Immune Function Network

CHAINS X & Y IN THE STRUCTURE ARE POLYPEPTIDES WHICH THE AUTHORS BELIEVE REPRESENTS EITHER THE N OR C-TERMINAL STRETCH CORRESPONDING TO THE CLONING ARTIFACTS AT EITHER TERMINI OF THE CEACAM-15 CONSTRUCT. HOWEVER THE POLYPEPTIDE CONNECTIVITY TO EITHER CHAIN A OR B IS NOT WELL DEFINED. THE SIDE CHAIN DENSITIES OF X & Y WERE ALSO NOT CLEAR AND HENCE MODELED AS POLY-ALANINE. THEREFORE, WE LIKE TO CALL CHAINS X & Y AS UNKNOWN PEPTIDES.

CEACAM15, Ig-like D1 domain, Ig superfamily, IMMUNE SYSTEM, Cell adhesion, Structural genomics, PSI-Biology, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network, IFN

TAALLTSKEMRFSAAEGAKVLLSVPDQEENLLSFSWYKGKDVNENFTIAHYKKSSDSLQLGKKVSGREEIYKDGSMMLRA
ITLEDTGFYTLQTFKAHGQQEVTHVHLQVYKIVTK