Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form

Structural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.

GHMKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAI
LHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNP
LAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGV
LLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAV
EGIEIVDDIYQYLISDALYNTSYETKNPFAQ

0.1M MES, 4.0M NACL, pH 6.0, EVAPORATION

ALLD, NAD(P)H-DEPENDENT OXIDOREDUCTASE, UREIDE PATHWAY, UREIDOGLYCOLATE, OXALURATE, ANTIPARALLEL BETA-SHEET FOLD, UREIDOGLYCOLATE DEHYDROGENASE, OXIDOREDUCTASE

MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILH
ADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLA
FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLL
GLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEG
IEIVDDIYQYLISDALYNTSYETKNPFAQ