Solution Structure of the Mediator Gall11 KIX Domain of C. Glabrata
Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction.
MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15
MEDIATOR COMPLEX SUBUNIT 15, TRANSCRIPTION REGULATORY PROTE IN GAL11, C. GLABRATA GAL11A KIX DOMAIN
MSSKETIPMHQRSQNVAELLTVLMDINKINGGDSTTAEKMKVHAKSFEAALFEKSSSKEEYQKTMKSKIDAMRSTRDKRK RESVGS
BACKBONE AND SIDE-CHAIN RESONANCES WERE ASSIGNED USING TRIPLE-RESONANCE MNR SPECTROSCOPY. THE STRUCTURE WAS CALCULATED FROM NOES FROM 15N - AND 13C - FILTERED NOESY EXPERIMENTS.
STRUCTURE REFINEMENT WAS PERFORMED THROUGH THE WENMR WEB-INTERACE WITH AMBER. BERTINI, I., CASE, D. A., FERELLA, L., GIACHETTI, A. & ROSATO, A., 2011, A GRID-ENABLED WEB PORTAL FOR NMR STRUCTURE REFINEMENT WITH AMBER. BIOINFORMATICS 27, 2384- -2390
I. BERTINI, D.A. CASE, L. FERELLA, A. GIACHETTI, A. ROSATO