Crystal structure of the tetramerisation domain of human CtIP

Ctip Tetramer Assembly is Required for DNA-End Resection and Repair.

CTBP-INTERACTING PROTEIN, CTIP, RETINOBLASTOMA-BINDING PROTEIN 8, RBBP-8, RETINOBLASTOMA-INTERACTING PROTEIN AND MYOSIN-LIKE, RIM, SPORULATION IN THE ABSENCE OF SPO11 PROTEIN 2 HOMOLOG, SAE2

200 MM LITHIUM SULPHATE, 100 MM SODIUM ACETATE PH 3.6, 32% (V/V) PEG 400

IDEAL-DIST CONTACT TERM CONTACT SETUP. ALL ATOMS HAVE CCP4 ATOM TYPE FROM LIBRARY.

GENE REGULATION, CTIP/RBBP8, DOUBLE-STRAND DNA BREAK REPAIR, DNA-END RESECTION, GENE CONVERSION, HOMOLOGOUS RECOMBINATION