Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
type: datablock
alternative label: 4CFN
link to mmcif: 4CFN.cif.gz
link to pdbml: 4CFN.xml.gz
link to pdbml noatom: 4CFN-noatom.xml.gz
link to pdbml extatom: 4CFN-extatom.xml.gz
link to doi: doi:10.2210/pdb4CFN/pdb
datablock name: 4CFN-noatom
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4CFN
type: atom sites
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
atom sites.entry id: 4CFN
atom sites.fract transf matrix11: 0.013517
atom sites.fract transf matrix12: 0
atom sites.fract transf matrix13: 0
atom sites.fract transf matrix21: 0
atom sites.fract transf matrix22: 0.00744
atom sites.fract transf matrix23: 0
atom sites.fract transf matrix31: 0
atom sites.fract transf matrix32: 0
atom sites.fract transf matrix33: 0.006763
atom sites.fract transf vector1: 0
atom sites.fract transf vector2: 0
atom sites.fract transf vector3: 0

4CFN
referenced by atom sites: 4CFN
referenced by cell: 4CFN
referenced by database PDB matrix: 4CFN
type: entry
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
entry.id: 4CFN
referenced by exptl: 4CFN,X-RAY DIFFRACTION
referenced by refine: 4CFN,X-RAY DIFFRACTION
referenced by reflns: http://rdf.wwpdb.org/pdb/4CFN/reflns/1
referenced by struct: 4CFN
referenced by struct keywords: 4CFN
referenced by symmetry: 4CFN
referenced by pdbx database status: 4CFN
referenced by pdbx entry details: 4CFN

http://rdf.wwpdb.org/pdb/4CFN/atom_type/C
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: C

http://rdf.wwpdb.org/pdb/4CFN/atom_type/F
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: F

http://rdf.wwpdb.org/pdb/4CFN/atom_type/N
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: N

http://rdf.wwpdb.org/pdb/4CFN/atom_type/O
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: O

http://rdf.wwpdb.org/pdb/4CFN/atom_type/P
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: P

http://rdf.wwpdb.org/pdb/4CFN/atom_type/S
type: atom type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
atom type.symbol: S

http://rdf.wwpdb.org/pdb/4CFN/audit_author/1
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 1
audit author.name: Carbain, B.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/2
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 2
audit author.name: Paterson, D.J.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/3
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 3
audit author.name: Anscombe, E.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/4
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 4
audit author.name: Campbell, A.

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type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 5
audit author.name: Cano, C.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/6
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 6
audit author.name: Echalier, A.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/7
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 7
audit author.name: Endicott, J.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/8
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 8
audit author.name: Golding, B.T.

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type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 9
audit author.name: Haggerty, K.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/10
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 10
audit author.name: Hardcastle, I.R.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/11
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 11
audit author.name: Jewsbury, P.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/12
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 12
audit author.name: Newell, D.R.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/13
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 13
audit author.name: Noble, M.E.M.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/14
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 14
audit author.name: Roche, C.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/15
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 15
audit author.name: Wang, L.Z.

http://rdf.wwpdb.org/pdb/4CFN/audit_author/16
type: audit author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit author.pdbx ordinal: 16
audit author.name: Griffin, R.

mmcif pdbx.dic,5.383
type: audit conform
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
audit conform.dict name: mmcif_pdbx.dic
audit conform.dict version: 5.383
audit conform.dict location: http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic

4CFN
type: cell
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
cell.entry id: 4CFN
cell.z PDB: 8
cell.angle alpha: 90
cell.angle beta: 90
cell.angle gamma: 90
cell.length a: 73.981
cell.length b: 134.416
cell.length c: 147.865

ALA
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: ALA
chem comp.formula: C3 H7 N O2
chem comp.formula weight: 89.093
chem comp.mon nstd flag: y
chem comp.name: ALANINE
chem comp.type: L-peptide linking
link to chem comp: ALA
referenced by chem comp atom: HXT,ALA
referenced by chem comp bond: OXT,HXT,ALA
referenced by entity poly seq: 2,ALA,231
referenced by chem comp atom: N,ALA
referenced by chem comp atom: CA,ALA
referenced by chem comp atom: C,ALA
referenced by chem comp atom: O,ALA
referenced by chem comp atom: CB,ALA
referenced by chem comp atom: OXT,ALA
referenced by chem comp atom: H,ALA
referenced by chem comp atom: H2,ALA
referenced by chem comp atom: HA,ALA
referenced by chem comp atom: HB1,ALA
referenced by chem comp atom: HB2,ALA
referenced by chem comp atom: HB3,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: C,O,ALA
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA
referenced by chem comp bond: CB,HB3,ALA
referenced by entity poly seq: 1,ALA,25
referenced by entity poly seq: 1,ALA,35
referenced by entity poly seq: 1,ALA,52
referenced by entity poly seq: 1,ALA,97
referenced by entity poly seq: 1,ALA,99
referenced by entity poly seq: 1,ALA,120
referenced by entity poly seq: 1,ALA,144
referenced by entity poly seq: 1,ALA,148
referenced by entity poly seq: 1,ALA,153
referenced by entity poly seq: 1,ALA,155
referenced by entity poly seq: 1,ALA,174
referenced by entity poly seq: 1,ALA,187
referenced by entity poly seq: 1,ALA,198
referenced by entity poly seq: 1,ALA,205
referenced by entity poly seq: 1,ALA,248
referenced by entity poly seq: 1,ALA,281
referenced by entity poly seq: 1,ALA,283
referenced by entity poly seq: 1,ALA,284
referenced by entity poly seq: 1,ALA,286
referenced by entity poly seq: 2,ALA,38
referenced by entity poly seq: 2,ALA,61
referenced by entity poly seq: 2,ALA,85
referenced by entity poly seq: 2,ALA,86
referenced by entity poly seq: 2,ALA,90
referenced by entity poly seq: 2,ALA,102
referenced by entity poly seq: 2,ALA,133
referenced by entity poly seq: 2,ALA,134
referenced by entity poly seq: 2,ALA,151
referenced by entity poly seq: 2,ALA,159
referenced by entity poly seq: 2,ALA,170
referenced by entity poly seq: 2,ALA,182
referenced by entity poly seq: 2,ALA,184
referenced by entity poly seq: 2,ALA,185
referenced by entity poly seq: 2,ALA,189
referenced by entity poly seq: 2,ALA,227

ARG
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: ARG
chem comp.formula: C6 H15 N4 O2 1
chem comp.formula weight: 175.209
chem comp.mon nstd flag: y
chem comp.name: ARGININE
chem comp.type: L-peptide linking
link to chem comp: ARG
referenced by chem comp atom: HXT,ARG
referenced by chem comp bond: OXT,HXT,ARG
referenced by entity poly seq: 2,ARG,236
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/13
referenced by chem comp atom: N,ARG
referenced by chem comp atom: CA,ARG
referenced by chem comp atom: C,ARG
referenced by chem comp atom: O,ARG
referenced by chem comp atom: CB,ARG
referenced by chem comp atom: CG,ARG
referenced by chem comp atom: CD,ARG
referenced by chem comp atom: NE,ARG
referenced by chem comp atom: CZ,ARG
referenced by chem comp atom: NH1,ARG
referenced by chem comp atom: NH2,ARG
referenced by chem comp atom: OXT,ARG
referenced by chem comp atom: H,ARG
referenced by chem comp atom: H2,ARG
referenced by chem comp atom: HA,ARG
referenced by chem comp atom: HB2,ARG
referenced by chem comp atom: HB3,ARG
referenced by chem comp atom: HG2,ARG
referenced by chem comp atom: HG3,ARG
referenced by chem comp atom: HD2,ARG
referenced by chem comp atom: HD3,ARG
referenced by chem comp atom: HE,ARG
referenced by chem comp atom: HH11,ARG
referenced by chem comp atom: HH12,ARG
referenced by chem comp atom: HH21,ARG
referenced by chem comp atom: HH22,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: C,O,ARG
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH1,HH11,ARG
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: NH2,HH21,ARG
referenced by chem comp bond: NH2,HH22,ARG
referenced by entity poly seq: 1,ARG,26
referenced by entity poly seq: 1,ARG,40
referenced by entity poly seq: 1,ARG,54
referenced by entity poly seq: 1,ARG,126
referenced by entity poly seq: 1,ARG,130
referenced by entity poly seq: 1,ARG,154
referenced by entity poly seq: 1,ARG,161
referenced by entity poly seq: 1,ARG,173
referenced by entity poly seq: 1,ARG,203
referenced by entity poly seq: 1,ARG,204
referenced by entity poly seq: 1,ARG,218
referenced by entity poly seq: 1,ARG,221
referenced by entity poly seq: 1,ARG,249
referenced by entity poly seq: 1,ARG,264
referenced by entity poly seq: 1,ARG,278
referenced by entity poly seq: 1,ARG,301

ASN
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: ASN
chem comp.formula: C4 H8 N2 O3
chem comp.formula weight: 132.118
chem comp.mon nstd flag: y
chem comp.name: ASPARAGINE
chem comp.type: L-peptide linking
link to chem comp: ASN
referenced by chem comp atom: HXT,ASN
referenced by chem comp bond: OXT,HXT,ASN
referenced by entity poly seq: 2,ASN,257
referenced by chem comp atom: N,ASN
referenced by chem comp atom: CA,ASN
referenced by chem comp atom: C,ASN
referenced by chem comp atom: O,ASN
referenced by chem comp atom: CB,ASN
referenced by chem comp atom: CG,ASN
referenced by chem comp atom: OD1,ASN
referenced by chem comp atom: ND2,ASN
referenced by chem comp atom: OXT,ASN
referenced by chem comp atom: H,ASN
referenced by chem comp atom: H2,ASN
referenced by chem comp atom: HA,ASN
referenced by chem comp atom: HB2,ASN
referenced by chem comp atom: HB3,ASN
referenced by chem comp atom: HD21,ASN
referenced by chem comp atom: HD22,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: C,O,ASN
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CG,OD1,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN
referenced by chem comp bond: ND2,HD22,ASN
referenced by entity poly seq: 1,ASN,7
referenced by entity poly seq: 1,ASN,27
referenced by entity poly seq: 1,ASN,63
referenced by entity poly seq: 1,ASN,66
referenced by entity poly seq: 1,ASN,78
referenced by entity poly seq: 1,ASN,136
referenced by entity poly seq: 1,ASN,140
referenced by entity poly seq: 1,ASN,276
referenced by entity poly seq: 2,ASN,34
referenced by entity poly seq: 2,ASN,55
referenced by entity poly seq: 2,ASN,63
referenced by entity poly seq: 2,ASN,138
referenced by entity poly seq: 2,ASN,152
referenced by entity poly seq: 2,ASN,241
referenced by entity poly seq: 2,ASN,251

ASP
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: ASP
chem comp.formula: C4 H7 N O4
chem comp.formula weight: 133.103
chem comp.mon nstd flag: y
chem comp.name: ASPARTIC ACID
chem comp.type: L-peptide linking
link to chem comp: ASP
referenced by chem comp atom: HXT,ASP
referenced by chem comp bond: OXT,HXT,ASP
referenced by entity poly seq: 2,ASP,219
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/17
referenced by chem comp atom: N,ASP
referenced by chem comp atom: CA,ASP
referenced by chem comp atom: C,ASP
referenced by chem comp atom: O,ASP
referenced by chem comp atom: CB,ASP
referenced by chem comp atom: CG,ASP
referenced by chem comp atom: OD1,ASP
referenced by chem comp atom: OD2,ASP
referenced by chem comp atom: OXT,ASP
referenced by chem comp atom: H,ASP
referenced by chem comp atom: H2,ASP
referenced by chem comp atom: HA,ASP
referenced by chem comp atom: HB2,ASP
referenced by chem comp atom: HB3,ASP
referenced by chem comp atom: HD2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: C,O,ASP
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CG,OD1,ASP
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: OD2,HD2,ASP
referenced by entity poly seq: 1,ASP,42
referenced by entity poly seq: 1,ASP,72
referenced by entity poly seq: 1,ASP,90
referenced by entity poly seq: 1,ASP,96
referenced by entity poly seq: 1,ASP,131
referenced by entity poly seq: 1,ASP,149
referenced by entity poly seq: 1,ASP,189
referenced by entity poly seq: 1,ASP,210
referenced by entity poly seq: 1,ASP,214
referenced by entity poly seq: 1,ASP,227
referenced by entity poly seq: 1,ASP,239
referenced by entity poly seq: 1,ASP,251
referenced by entity poly seq: 1,ASP,260
referenced by entity poly seq: 1,ASP,262
referenced by entity poly seq: 1,ASP,274
referenced by entity poly seq: 1,ASP,292
referenced by entity poly seq: 2,ASP,3
referenced by entity poly seq: 2,ASP,7
referenced by entity poly seq: 2,ASP,31
referenced by entity poly seq: 2,ASP,42
referenced by entity poly seq: 2,ASP,66
referenced by entity poly seq: 2,ASP,109
referenced by entity poly seq: 2,ASP,110
referenced by entity poly seq: 2,ASP,131
referenced by entity poly seq: 2,ASP,169
referenced by entity poly seq: 2,ASP,171
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/2
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/8
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/9
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/16

CYS
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: CYS
chem comp.formula: C3 H7 N O2 S
chem comp.formula weight: 121.158
chem comp.mon nstd flag: y
chem comp.name: CYSTEINE
chem comp.type: L-peptide linking
link to chem comp: CYS
referenced by chem comp atom: HXT,CYS
referenced by chem comp bond: OXT,HXT,CYS
referenced by entity poly seq: 2,CYS,216
referenced by chem comp atom: N,CYS
referenced by chem comp atom: CA,CYS
referenced by chem comp atom: C,CYS
referenced by chem comp atom: O,CYS
referenced by chem comp atom: CB,CYS
referenced by chem comp atom: SG,CYS
referenced by chem comp atom: OXT,CYS
referenced by chem comp atom: H,CYS
referenced by chem comp atom: H2,CYS
referenced by chem comp atom: HA,CYS
referenced by chem comp atom: HB2,CYS
referenced by chem comp atom: HB3,CYS
referenced by chem comp atom: HG,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: C,O,CYS
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: SG,HG,CYS
referenced by entity poly seq: 1,CYS,122
referenced by entity poly seq: 1,CYS,181
referenced by entity poly seq: 1,CYS,195
referenced by entity poly seq: 2,CYS,19
referenced by entity poly seq: 2,CYS,153

DTT
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: DTT
chem comp.formula: C4 H10 O2 S2
chem comp.formula weight: 154.251
chem comp.name: 2,3-DIHYDROXY-1,4-DITHIOBUTANE
chem comp.pdbx synonyms: 1,4-DITHIOTHREITOL
chem comp.type: non-polymer
link to chem comp: DTT
referenced by chem comp atom: HS2,DTT
referenced by chem comp bond: S4,HS2,DTT
referenced by chem comp atom: S1,DTT
referenced by chem comp atom: C1,DTT
referenced by chem comp atom: C2,DTT
referenced by chem comp atom: O2,DTT
referenced by chem comp atom: C3,DTT
referenced by chem comp atom: O3,DTT
referenced by chem comp atom: C4,DTT
referenced by chem comp atom: S4,DTT
referenced by chem comp atom: HS1,DTT
referenced by chem comp atom: H11,DTT
referenced by chem comp atom: H12,DTT
referenced by chem comp atom: H2,DTT
referenced by chem comp atom: HO2,DTT
referenced by chem comp atom: H3,DTT
referenced by chem comp atom: HO3,DTT
referenced by chem comp atom: H41,DTT
referenced by chem comp atom: H42,DTT
referenced by chem comp bond: S1,C1,DTT
referenced by chem comp bond: S1,HS1,DTT
referenced by chem comp bond: C1,C2,DTT
referenced by chem comp bond: C1,H11,DTT
referenced by chem comp bond: C1,H12,DTT
referenced by chem comp bond: C2,O2,DTT
referenced by chem comp bond: C2,C3,DTT
referenced by chem comp bond: C2,H2,DTT
referenced by chem comp bond: O2,HO2,DTT
referenced by chem comp bond: C3,O3,DTT
referenced by chem comp bond: C3,C4,DTT
referenced by chem comp bond: C3,H3,DTT
referenced by chem comp bond: O3,HO3,DTT
referenced by chem comp bond: C4,S4,DTT
referenced by chem comp bond: C4,H41,DTT
referenced by chem comp bond: C4,H42,DTT

GLN
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: GLN
chem comp.formula: C5 H10 N2 O3
chem comp.formula weight: 146.144
chem comp.mon nstd flag: y
chem comp.name: GLUTAMINE
chem comp.type: L-peptide linking
link to chem comp: GLN
referenced by chem comp atom: HXT,GLN
referenced by chem comp bond: OXT,HXT,GLN
referenced by entity poly seq: 2,GLN,233
referenced by chem comp atom: N,GLN
referenced by chem comp atom: CA,GLN
referenced by chem comp atom: C,GLN
referenced by chem comp atom: O,GLN
referenced by chem comp atom: CB,GLN
referenced by chem comp atom: CG,GLN
referenced by chem comp atom: CD,GLN
referenced by chem comp atom: OE1,GLN
referenced by chem comp atom: NE2,GLN
referenced by chem comp atom: OXT,GLN
referenced by chem comp atom: H,GLN
referenced by chem comp atom: H2,GLN
referenced by chem comp atom: HA,GLN
referenced by chem comp atom: HB2,GLN
referenced by chem comp atom: HB3,GLN
referenced by chem comp atom: HG2,GLN
referenced by chem comp atom: HG3,GLN
referenced by chem comp atom: HE21,GLN
referenced by chem comp atom: HE22,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: C,O,GLN
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CD,OE1,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN
referenced by chem comp bond: NE2,HE22,GLN
referenced by entity poly seq: 1,GLN,9
referenced by entity poly seq: 1,GLN,89
referenced by entity poly seq: 1,GLN,114
referenced by entity poly seq: 1,GLN,117
referenced by entity poly seq: 1,GLN,135
referenced by entity poly seq: 1,GLN,215
referenced by entity poly seq: 1,GLN,250
referenced by entity poly seq: 1,GLN,269
referenced by entity poly seq: 1,GLN,291
referenced by entity poly seq: 2,GLN,29
referenced by entity poly seq: 2,GLN,54
referenced by entity poly seq: 2,GLN,80
referenced by entity poly seq: 2,GLN,116
referenced by entity poly seq: 2,GLN,139
referenced by entity poly seq: 2,GLN,143
referenced by entity poly seq: 2,GLN,148
referenced by entity poly seq: 2,GLN,149
referenced by entity poly seq: 2,GLN,196
referenced by entity poly seq: 2,GLN,222
referenced by entity poly seq: 2,GLN,229
referenced by entity poly seq: 2,GLN,232

GLU
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: GLU
chem comp.formula: C5 H9 N O4
chem comp.formula weight: 147.129
chem comp.mon nstd flag: y
chem comp.name: GLUTAMIC ACID
chem comp.type: L-peptide linking
link to chem comp: GLU
referenced by chem comp atom: HXT,GLU
referenced by chem comp bond: OXT,HXT,GLU
referenced by entity poly seq: 2,GLU,254
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/4
referenced by chem comp atom: N,GLU
referenced by chem comp atom: CA,GLU
referenced by chem comp atom: C,GLU
referenced by chem comp atom: O,GLU
referenced by chem comp atom: CB,GLU
referenced by chem comp atom: CG,GLU
referenced by chem comp atom: CD,GLU
referenced by chem comp atom: OE1,GLU
referenced by chem comp atom: OE2,GLU
referenced by chem comp atom: OXT,GLU
referenced by chem comp atom: H,GLU
referenced by chem comp atom: H2,GLU
referenced by chem comp atom: HA,GLU
referenced by chem comp atom: HB2,GLU
referenced by chem comp atom: HB3,GLU
referenced by chem comp atom: HG2,GLU
referenced by chem comp atom: HG3,GLU
referenced by chem comp atom: HE2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: C,O,GLU
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CD,OE1,GLU
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: OE2,HE2,GLU
referenced by entity poly seq: 1,GLU,6
referenced by entity poly seq: 1,GLU,12
referenced by entity poly seq: 1,GLU,16
referenced by entity poly seq: 1,GLU,32
referenced by entity poly seq: 1,GLU,44
referenced by entity poly seq: 1,GLU,46
referenced by entity poly seq: 1,GLU,55
referenced by entity poly seq: 1,GLU,61
referenced by entity poly seq: 1,GLU,77
referenced by entity poly seq: 1,GLU,85
referenced by entity poly seq: 1,GLU,142
referenced by entity poly seq: 1,GLU,166
referenced by entity poly seq: 1,GLU,176
referenced by entity poly seq: 1,GLU,199
referenced by entity poly seq: 1,GLU,212
referenced by entity poly seq: 1,GLU,228
referenced by entity poly seq: 1,GLU,261
referenced by entity poly seq: 2,GLU,6
referenced by entity poly seq: 2,GLU,14
referenced by entity poly seq: 2,GLU,16
referenced by entity poly seq: 2,GLU,46
referenced by entity poly seq: 2,GLU,49
referenced by entity poly seq: 2,GLU,50
referenced by entity poly seq: 2,GLU,56
referenced by entity poly seq: 2,GLU,94
referenced by entity poly seq: 2,GLU,95
referenced by entity poly seq: 2,GLU,100
referenced by entity poly seq: 2,GLU,103
referenced by entity poly seq: 2,GLU,121
referenced by entity poly seq: 2,GLU,156
referenced by entity poly seq: 2,GLU,164
referenced by entity poly seq: 2,GLU,200

GLY
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: GLY
chem comp.formula: C2 H5 N O2
chem comp.formula weight: 75.067
chem comp.mon nstd flag: y
chem comp.name: GLYCINE
chem comp.type: peptide linking
link to chem comp: GLY
referenced by chem comp atom: HXT,GLY
referenced by chem comp bond: OXT,HXT,GLY
referenced by entity poly seq: 2,GLY,246
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/10
referenced by chem comp atom: N,GLY
referenced by chem comp atom: CA,GLY
referenced by chem comp atom: C,GLY
referenced by chem comp atom: O,GLY
referenced by chem comp atom: OXT,GLY
referenced by chem comp atom: H,GLY
referenced by chem comp atom: H2,GLY
referenced by chem comp atom: HA2,GLY
referenced by chem comp atom: HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: C,O,GLY
referenced by chem comp bond: C,OXT,GLY
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,GLY,3
referenced by entity poly seq: 1,GLY,15
referenced by entity poly seq: 1,GLY,17
referenced by entity poly seq: 1,GLY,20
referenced by entity poly seq: 1,GLY,31
referenced by entity poly seq: 1,GLY,47
referenced by entity poly seq: 1,GLY,102
referenced by entity poly seq: 1,GLY,118
referenced by entity poly seq: 1,GLY,143
referenced by entity poly seq: 1,GLY,151
referenced by entity poly seq: 1,GLY,157
referenced by entity poly seq: 1,GLY,180
referenced by entity poly seq: 1,GLY,194
referenced by entity poly seq: 1,GLY,209
referenced by entity poly seq: 1,GLY,224
referenced by entity poly seq: 1,GLY,233
referenced by entity poly seq: 1,GLY,263
referenced by entity poly seq: 2,GLY,24
referenced by entity poly seq: 2,GLY,48
referenced by entity poly seq: 2,GLY,77
referenced by entity poly seq: 2,GLY,83
referenced by entity poly seq: 2,GLY,163
referenced by entity poly seq: 2,GLY,183
referenced by entity poly seq: 2,GLY,195
referenced by entity poly seq: 2,GLY,207
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/1

HIS
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: HIS
chem comp.formula: C6 H10 N3 O2 1
chem comp.formula weight: 156.162
chem comp.mon nstd flag: y
chem comp.name: HISTIDINE
chem comp.type: L-peptide linking
link to chem comp: HIS
referenced by chem comp atom: HXT,HIS
referenced by chem comp bond: OXT,HXT,HIS
referenced by entity poly seq: 2,HIS,245
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/11
referenced by chem comp atom: N,HIS
referenced by chem comp atom: CA,HIS
referenced by chem comp atom: C,HIS
referenced by chem comp atom: O,HIS
referenced by chem comp atom: CB,HIS
referenced by chem comp atom: CG,HIS
referenced by chem comp atom: ND1,HIS
referenced by chem comp atom: CD2,HIS
referenced by chem comp atom: CE1,HIS
referenced by chem comp atom: NE2,HIS
referenced by chem comp atom: OXT,HIS
referenced by chem comp atom: H,HIS
referenced by chem comp atom: H2,HIS
referenced by chem comp atom: HA,HIS
referenced by chem comp atom: HB2,HIS
referenced by chem comp atom: HB3,HIS
referenced by chem comp atom: HD1,HIS
referenced by chem comp atom: HD2,HIS
referenced by chem comp atom: HE1,HIS
referenced by chem comp atom: HE2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: C,O,HIS
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CD2,NE2,HIS
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: NE2,HE2,HIS
referenced by entity poly seq: 1,HIS,64
referenced by entity poly seq: 1,HIS,75
referenced by entity poly seq: 1,HIS,88
referenced by entity poly seq: 1,HIS,123
referenced by entity poly seq: 1,HIS,125
referenced by entity poly seq: 1,HIS,129
referenced by entity poly seq: 1,HIS,165
referenced by entity poly seq: 1,HIS,272
referenced by entity poly seq: 1,HIS,287
referenced by entity poly seq: 1,HIS,299
referenced by entity poly seq: 2,HIS,5
referenced by entity poly seq: 2,HIS,9
referenced by entity poly seq: 2,HIS,59
referenced by entity poly seq: 2,HIS,122
referenced by entity poly seq: 2,HIS,147
referenced by entity poly seq: 2,HIS,187
referenced by entity poly seq: 2,HIS,221
referenced by entity poly seq: 2,HIS,230

HOH
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: HOH
chem comp.formula: H2 O
chem comp.formula weight: 18.015
chem comp.name: WATER
chem comp.type: non-polymer
link to chem comp: HOH
referenced by chem comp atom: H2,HOH
referenced by chem comp bond: O,H2,HOH
referenced by chem comp atom: O,HOH
referenced by chem comp atom: H1,HOH
referenced by chem comp bond: O,H1,HOH

ILE
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: ILE
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: ISOLEUCINE
chem comp.type: L-peptide linking
link to chem comp: ILE
referenced by chem comp atom: HXT,ILE
referenced by chem comp bond: OXT,HXT,ILE
referenced by entity poly seq: 2,ILE,235
referenced by chem comp atom: N,ILE
referenced by chem comp atom: CA,ILE
referenced by chem comp atom: C,ILE
referenced by chem comp atom: O,ILE
referenced by chem comp atom: CB,ILE
referenced by chem comp atom: CG1,ILE
referenced by chem comp atom: CG2,ILE
referenced by chem comp atom: CD1,ILE
referenced by chem comp atom: OXT,ILE
referenced by chem comp atom: H,ILE
referenced by chem comp atom: H2,ILE
referenced by chem comp atom: HA,ILE
referenced by chem comp atom: HB,ILE
referenced by chem comp atom: HG12,ILE
referenced by chem comp atom: HG13,ILE
referenced by chem comp atom: HG21,ILE
referenced by chem comp atom: HG22,ILE
referenced by chem comp atom: HG23,ILE
referenced by chem comp atom: HD11,ILE
referenced by chem comp atom: HD12,ILE
referenced by chem comp atom: HD13,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: C,O,ILE
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE
referenced by chem comp bond: CD1,HD13,ILE
referenced by entity poly seq: 1,ILE,14
referenced by entity poly seq: 1,ILE,39
referenced by entity poly seq: 1,ILE,53
referenced by entity poly seq: 1,ILE,56
referenced by entity poly seq: 1,ILE,67
referenced by entity poly seq: 1,ILE,74
referenced by entity poly seq: 1,ILE,103
referenced by entity poly seq: 1,ILE,108
referenced by entity poly seq: 1,ILE,139
referenced by entity poly seq: 1,ILE,145
referenced by entity poly seq: 1,ILE,177
referenced by entity poly seq: 1,ILE,190
referenced by entity poly seq: 1,ILE,196
referenced by entity poly seq: 1,ILE,213
referenced by entity poly seq: 1,ILE,219
referenced by entity poly seq: 1,ILE,279
referenced by entity poly seq: 2,ILE,8
referenced by entity poly seq: 2,ILE,32
referenced by entity poly seq: 2,ILE,39
referenced by entity poly seq: 2,ILE,65
referenced by entity poly seq: 2,ILE,96
referenced by entity poly seq: 2,ILE,107
referenced by entity poly seq: 2,ILE,168
referenced by entity poly seq: 2,ILE,181
referenced by entity poly seq: 2,ILE,203

JYM
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: JYM
chem comp.formula: C13 H16 F3 N5 O
chem comp.formula weight: 315.294
chem comp.name: 6-(cyclohexylmethoxy)-8-(trifluoromethyl)-9H-purin-2-amine
chem comp.type: non-polymer
link to chem comp: JYM
referenced by chem comp atom: HAQ2,JYM
referenced by chem comp bond: CAQ,HAQ2,JYM
referenced by chem comp atom: FAT,JYM
referenced by chem comp atom: CAS,JYM
referenced by chem comp atom: FAU,JYM
referenced by chem comp atom: FAV,JYM
referenced by chem comp atom: C8,JYM
referenced by chem comp atom: N9,JYM
referenced by chem comp atom: N7,JYM
referenced by chem comp atom: C5,JYM
referenced by chem comp atom: C4,JYM
referenced by chem comp atom: N3,JYM
referenced by chem comp atom: C2,JYM
referenced by chem comp atom: N2,JYM
referenced by chem comp atom: N1,JYM
referenced by chem comp atom: C6,JYM
referenced by chem comp atom: O6,JYM
referenced by chem comp atom: CAL,JYM
referenced by chem comp atom: CAM,JYM
referenced by chem comp atom: CAN,JYM
referenced by chem comp atom: CAO,JYM
referenced by chem comp atom: CAP,JYM
referenced by chem comp atom: CAQ,JYM
referenced by chem comp atom: CAR,JYM
referenced by chem comp atom: H9,JYM
referenced by chem comp atom: H21N,JYM
referenced by chem comp atom: H22N,JYM
referenced by chem comp atom: HAL1,JYM
referenced by chem comp atom: HAL2,JYM
referenced by chem comp atom: HAM,JYM
referenced by chem comp atom: HAN1,JYM
referenced by chem comp atom: HAN2,JYM
referenced by chem comp atom: HAR1,JYM
referenced by chem comp atom: HAR2,JYM
referenced by chem comp atom: HAO1,JYM
referenced by chem comp atom: HAO2,JYM
referenced by chem comp atom: HAP1,JYM
referenced by chem comp atom: HAP2,JYM
referenced by chem comp atom: HAQ1,JYM
referenced by chem comp bond: FAT,CAS,JYM
referenced by chem comp bond: CAS,FAU,JYM
referenced by chem comp bond: CAS,FAV,JYM
referenced by chem comp bond: CAS,C8,JYM
referenced by chem comp bond: C8,N9,JYM
referenced by chem comp bond: C8,N7,JYM
referenced by chem comp bond: N9,C4,JYM
referenced by chem comp bond: N7,C5,JYM
referenced by chem comp bond: C5,C4,JYM
referenced by chem comp bond: C5,C6,JYM
referenced by chem comp bond: C4,N3,JYM
referenced by chem comp bond: N3,C2,JYM
referenced by chem comp bond: C2,N2,JYM
referenced by chem comp bond: C2,N1,JYM
referenced by chem comp bond: N1,C6,JYM
referenced by chem comp bond: C6,O6,JYM
referenced by chem comp bond: O6,CAL,JYM
referenced by chem comp bond: CAL,CAM,JYM
referenced by chem comp bond: CAM,CAN,JYM
referenced by chem comp bond: CAM,CAR,JYM
referenced by chem comp bond: CAN,CAO,JYM
referenced by chem comp bond: CAO,CAP,JYM
referenced by chem comp bond: CAP,CAQ,JYM
referenced by chem comp bond: CAQ,CAR,JYM
referenced by chem comp bond: N9,H9,JYM
referenced by chem comp bond: N2,H21N,JYM
referenced by chem comp bond: N2,H22N,JYM
referenced by chem comp bond: CAL,HAL1,JYM
referenced by chem comp bond: CAL,HAL2,JYM
referenced by chem comp bond: CAM,HAM,JYM
referenced by chem comp bond: CAN,HAN1,JYM
referenced by chem comp bond: CAN,HAN2,JYM
referenced by chem comp bond: CAR,HAR1,JYM

LEU
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: LEU
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: LEUCINE
chem comp.type: L-peptide linking
link to chem comp: LEU
referenced by chem comp atom: HXT,LEU
referenced by chem comp bond: OXT,HXT,LEU
referenced by entity poly seq: 2,LEU,258
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/14
referenced by chem comp atom: N,LEU
referenced by chem comp atom: CA,LEU
referenced by chem comp atom: C,LEU
referenced by chem comp atom: O,LEU
referenced by chem comp atom: CB,LEU
referenced by chem comp atom: CG,LEU
referenced by chem comp atom: CD1,LEU
referenced by chem comp atom: CD2,LEU
referenced by chem comp atom: OXT,LEU
referenced by chem comp atom: H,LEU
referenced by chem comp atom: H2,LEU
referenced by chem comp atom: HA,LEU
referenced by chem comp atom: HB2,LEU
referenced by chem comp atom: HB3,LEU
referenced by chem comp atom: HG,LEU
referenced by chem comp atom: HD11,LEU
referenced by chem comp atom: HD12,LEU
referenced by chem comp atom: HD13,LEU
referenced by chem comp atom: HD21,LEU
referenced by chem comp atom: HD22,LEU
referenced by chem comp atom: HD23,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: C,O,LEU
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU
referenced by chem comp bond: CD2,HD23,LEU
referenced by entity poly seq: 1,LEU,29
referenced by entity poly seq: 1,LEU,36
referenced by entity poly seq: 1,LEU,41
referenced by entity poly seq: 1,LEU,58
referenced by entity poly seq: 1,LEU,59
referenced by entity poly seq: 1,LEU,62
referenced by entity poly seq: 1,LEU,70
referenced by entity poly seq: 1,LEU,71
referenced by entity poly seq: 1,LEU,80
referenced by entity poly seq: 1,LEU,82
referenced by entity poly seq: 1,LEU,87
referenced by entity poly seq: 1,LEU,91
referenced by entity poly seq: 1,LEU,100
referenced by entity poly seq: 1,LEU,105
referenced by entity poly seq: 1,LEU,107
referenced by entity poly seq: 1,LEU,112
referenced by entity poly seq: 1,LEU,115
referenced by entity poly seq: 1,LEU,116
referenced by entity poly seq: 1,LEU,119
referenced by entity poly seq: 1,LEU,128
referenced by entity poly seq: 1,LEU,132
referenced by entity poly seq: 1,LEU,137
referenced by entity poly seq: 1,LEU,138
referenced by entity poly seq: 1,LEU,147
referenced by entity poly seq: 1,LEU,152
referenced by entity poly seq: 1,LEU,170

LYS
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: LYS
chem comp.formula: C6 H15 N2 O2 1
chem comp.formula weight: 147.195
chem comp.mon nstd flag: y
chem comp.name: LYSINE
chem comp.type: L-peptide linking
link to chem comp: LYS
referenced by chem comp atom: HXT,LYS
referenced by chem comp bond: OXT,HXT,LYS
referenced by entity poly seq: 2,LYS,243
referenced by chem comp atom: N,LYS
referenced by chem comp atom: CA,LYS
referenced by chem comp atom: C,LYS
referenced by chem comp atom: O,LYS
referenced by chem comp atom: CB,LYS
referenced by chem comp atom: CG,LYS
referenced by chem comp atom: CD,LYS
referenced by chem comp atom: CE,LYS
referenced by chem comp atom: NZ,LYS
referenced by chem comp atom: OXT,LYS
referenced by chem comp atom: H,LYS
referenced by chem comp atom: H2,LYS
referenced by chem comp atom: HA,LYS
referenced by chem comp atom: HB2,LYS
referenced by chem comp atom: HB3,LYS
referenced by chem comp atom: HG2,LYS
referenced by chem comp atom: HG3,LYS
referenced by chem comp atom: HD2,LYS
referenced by chem comp atom: HD3,LYS
referenced by chem comp atom: HE2,LYS
referenced by chem comp atom: HE3,LYS
referenced by chem comp atom: HZ1,LYS
referenced by chem comp atom: HZ2,LYS
referenced by chem comp atom: HZ3,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: C,O,LYS
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS
referenced by chem comp bond: NZ,HZ3,LYS
referenced by entity poly seq: 1,LYS,10
referenced by entity poly seq: 1,LYS,13
referenced by entity poly seq: 1,LYS,24
referenced by entity poly seq: 1,LYS,28
referenced by entity poly seq: 1,LYS,37
referenced by entity poly seq: 1,LYS,38
referenced by entity poly seq: 1,LYS,60
referenced by entity poly seq: 1,LYS,69
referenced by entity poly seq: 1,LYS,79
referenced by entity poly seq: 1,LYS,92
referenced by entity poly seq: 1,LYS,93
referenced by entity poly seq: 1,LYS,109
referenced by entity poly seq: 1,LYS,133
referenced by entity poly seq: 1,LYS,146
referenced by entity poly seq: 1,LYS,182
referenced by entity poly seq: 1,LYS,241
referenced by entity poly seq: 1,LYS,246
referenced by entity poly seq: 1,LYS,254
referenced by entity poly seq: 1,LYS,277
referenced by entity poly seq: 1,LYS,282
referenced by entity poly seq: 1,LYS,295

MET
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: MET
chem comp.formula: C5 H11 N O2 S
chem comp.formula weight: 149.211
chem comp.mon nstd flag: y
chem comp.name: METHIONINE
chem comp.type: L-peptide linking
link to chem comp: MET
referenced by chem comp atom: HXT,MET
referenced by chem comp bond: OXT,HXT,MET
referenced by entity poly seq: 2,MET,218
referenced by chem comp atom: N,MET
referenced by chem comp atom: CA,MET
referenced by chem comp atom: C,MET
referenced by chem comp atom: O,MET
referenced by chem comp atom: CB,MET
referenced by chem comp atom: CG,MET
referenced by chem comp atom: SD,MET
referenced by chem comp atom: CE,MET
referenced by chem comp atom: OXT,MET
referenced by chem comp atom: H,MET
referenced by chem comp atom: H2,MET
referenced by chem comp atom: HA,MET
referenced by chem comp atom: HB2,MET
referenced by chem comp atom: HB3,MET
referenced by chem comp atom: HG2,MET
referenced by chem comp atom: HG3,MET
referenced by chem comp atom: HE1,MET
referenced by chem comp atom: HE2,MET
referenced by chem comp atom: HE3,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: C,O,MET
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET
referenced by chem comp bond: CE,HE3,MET
referenced by entity poly seq: 1,MET,5
referenced by entity poly seq: 1,MET,95
referenced by entity poly seq: 1,MET,200
referenced by entity poly seq: 1,MET,237
referenced by entity poly seq: 1,MET,270
referenced by entity poly seq: 2,MET,15
referenced by entity poly seq: 2,MET,26
referenced by entity poly seq: 2,MET,36
referenced by entity poly seq: 2,MET,72
referenced by entity poly seq: 2,MET,87
referenced by entity poly seq: 2,MET,120
referenced by entity poly seq: 2,MET,160

PHE
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: PHE
chem comp.formula: C9 H11 N O2
chem comp.formula weight: 165.189
chem comp.mon nstd flag: y
chem comp.name: PHENYLALANINE
chem comp.type: L-peptide linking
link to chem comp: PHE
referenced by chem comp atom: HXT,PHE
referenced by chem comp bond: OXT,HXT,PHE
referenced by entity poly seq: 2,PHE,186
referenced by chem comp atom: N,PHE
referenced by chem comp atom: CA,PHE
referenced by chem comp atom: C,PHE
referenced by chem comp atom: O,PHE
referenced by chem comp atom: CB,PHE
referenced by chem comp atom: CG,PHE
referenced by chem comp atom: CD1,PHE
referenced by chem comp atom: CD2,PHE
referenced by chem comp atom: CE1,PHE
referenced by chem comp atom: CE2,PHE
referenced by chem comp atom: CZ,PHE
referenced by chem comp atom: OXT,PHE
referenced by chem comp atom: H,PHE
referenced by chem comp atom: H2,PHE
referenced by chem comp atom: HA,PHE
referenced by chem comp atom: HB2,PHE
referenced by chem comp atom: HB3,PHE
referenced by chem comp atom: HD1,PHE
referenced by chem comp atom: HD2,PHE
referenced by chem comp atom: HE1,PHE
referenced by chem comp atom: HE2,PHE
referenced by chem comp atom: HZ,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: C,O,PHE
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CE1,CZ,PHE
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CZ,HZ,PHE
referenced by entity poly seq: 1,PHE,8
referenced by entity poly seq: 1,PHE,84
referenced by entity poly seq: 1,PHE,86
referenced by entity poly seq: 1,PHE,94
referenced by entity poly seq: 1,PHE,113
referenced by entity poly seq: 1,PHE,121
referenced by entity poly seq: 1,PHE,150
referenced by entity poly seq: 1,PHE,156
referenced by entity poly seq: 1,PHE,197
referenced by entity poly seq: 1,PHE,207
referenced by entity poly seq: 1,PHE,217
referenced by entity poly seq: 1,PHE,220
referenced by entity poly seq: 1,PHE,244
referenced by entity poly seq: 1,PHE,252
referenced by entity poly seq: 1,PHE,289
referenced by entity poly seq: 1,PHE,290
referenced by entity poly seq: 2,PHE,68
referenced by entity poly seq: 2,PHE,93
referenced by entity poly seq: 2,PHE,104
referenced by entity poly seq: 2,PHE,130
referenced by entity poly seq: 2,PHE,140
referenced by entity poly seq: 2,PHE,145
referenced by entity poly seq: 2,PHE,161

PRO
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: PRO
chem comp.formula: C5 H9 N O2
chem comp.formula weight: 115.13
chem comp.mon nstd flag: y
chem comp.name: PROLINE
chem comp.type: L-peptide linking
link to chem comp: PRO
referenced by chem comp atom: HXT,PRO
referenced by chem comp bond: OXT,HXT,PRO
referenced by entity poly seq: 2,PRO,253
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/7
referenced by chem comp atom: N,PRO
referenced by chem comp atom: CA,PRO
referenced by chem comp atom: C,PRO
referenced by chem comp atom: O,PRO
referenced by chem comp atom: CB,PRO
referenced by chem comp atom: CG,PRO
referenced by chem comp atom: CD,PRO
referenced by chem comp atom: OXT,PRO
referenced by chem comp atom: H,PRO
referenced by chem comp atom: HA,PRO
referenced by chem comp atom: HB2,PRO
referenced by chem comp atom: HB3,PRO
referenced by chem comp atom: HG2,PRO
referenced by chem comp atom: HG3,PRO
referenced by chem comp atom: HD2,PRO
referenced by chem comp atom: HD3,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: C,O,PRO
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CD,HD2,PRO
referenced by chem comp bond: CD,HD3,PRO
referenced by entity poly seq: 1,PRO,2
referenced by entity poly seq: 1,PRO,49
referenced by entity poly seq: 1,PRO,65
referenced by entity poly seq: 1,PRO,104
referenced by entity poly seq: 1,PRO,106
referenced by entity poly seq: 1,PRO,134
referenced by entity poly seq: 1,PRO,159
referenced by entity poly seq: 1,PRO,175
referenced by entity poly seq: 1,PRO,208
referenced by entity poly seq: 1,PRO,226
referenced by entity poly seq: 1,PRO,232
referenced by entity poly seq: 1,PRO,238
referenced by entity poly seq: 1,PRO,242
referenced by entity poly seq: 1,PRO,245
referenced by entity poly seq: 1,PRO,257
referenced by entity poly seq: 1,PRO,258
referenced by entity poly seq: 1,PRO,275
referenced by entity poly seq: 1,PRO,288
referenced by entity poly seq: 1,PRO,296
referenced by entity poly seq: 1,PRO,298
referenced by entity poly seq: 2,PRO,2
referenced by entity poly seq: 2,PRO,21
referenced by entity poly seq: 2,PRO,30
referenced by entity poly seq: 2,PRO,98
referenced by entity poly seq: 2,PRO,99
referenced by entity poly seq: 2,PRO,135
referenced by entity poly seq: 2,PRO,150
referenced by entity poly seq: 2,PRO,172
referenced by entity poly seq: 2,PRO,178
referenced by entity poly seq: 2,PRO,199
referenced by entity poly seq: 2,PRO,215
referenced by entity poly seq: 2,PRO,228
referenced by entity poly seq: 2,PRO,252

SER
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: SER
chem comp.formula: C3 H7 N O3
chem comp.formula weight: 105.093
chem comp.mon nstd flag: y
chem comp.name: SERINE
chem comp.type: L-peptide linking
link to chem comp: SER
referenced by chem comp atom: HXT,SER
referenced by chem comp bond: OXT,HXT,SER
referenced by entity poly seq: 2,SER,248
referenced by chem comp atom: N,SER
referenced by chem comp atom: CA,SER
referenced by chem comp atom: C,SER
referenced by chem comp atom: O,SER
referenced by chem comp atom: CB,SER
referenced by chem comp atom: OG,SER
referenced by chem comp atom: OXT,SER
referenced by chem comp atom: H,SER
referenced by chem comp atom: H2,SER
referenced by chem comp atom: HA,SER
referenced by chem comp atom: HB2,SER
referenced by chem comp atom: HB3,SER
referenced by chem comp atom: HG,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: C,O,SER
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: OG,HG,SER
referenced by entity poly seq: 1,SER,4
referenced by entity poly seq: 1,SER,50
referenced by entity poly seq: 1,SER,57
referenced by entity poly seq: 1,SER,98
referenced by entity poly seq: 1,SER,110
referenced by entity poly seq: 1,SER,124
referenced by entity poly seq: 1,SER,185
referenced by entity poly seq: 1,SER,192
referenced by entity poly seq: 1,SER,211
referenced by entity poly seq: 1,SER,236
referenced by entity poly seq: 1,SER,243
referenced by entity poly seq: 1,SER,253
referenced by entity poly seq: 1,SER,265
referenced by entity poly seq: 1,SER,268
referenced by entity poly seq: 1,SER,280
referenced by entity poly seq: 2,SER,35
referenced by entity poly seq: 2,SER,70
referenced by entity poly seq: 2,SER,71
referenced by entity poly seq: 2,SER,73
referenced by entity poly seq: 2,SER,91
referenced by entity poly seq: 2,SER,157
referenced by entity poly seq: 2,SER,166
referenced by entity poly seq: 2,SER,179
referenced by entity poly seq: 2,SER,197
referenced by entity poly seq: 2,SER,201
referenced by entity poly seq: 2,SER,212
referenced by entity poly seq: 2,SER,234
referenced by entity poly seq: 2,SER,242

THR
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: THR
chem comp.formula: C4 H9 N O3
chem comp.formula weight: 119.119
chem comp.mon nstd flag: y
chem comp.name: THREONINE
chem comp.type: L-peptide linking
link to chem comp: THR
referenced by chem comp atom: HXT,THR
referenced by chem comp bond: OXT,HXT,THR
referenced by entity poly seq: 2,THR,255
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/3
referenced by chem comp atom: N,THR
referenced by chem comp atom: CA,THR
referenced by chem comp atom: C,THR
referenced by chem comp atom: O,THR
referenced by chem comp atom: CB,THR
referenced by chem comp atom: OG1,THR
referenced by chem comp atom: CG2,THR
referenced by chem comp atom: OXT,THR
referenced by chem comp atom: H,THR
referenced by chem comp atom: H2,THR
referenced by chem comp atom: HA,THR
referenced by chem comp atom: HB,THR
referenced by chem comp atom: HG1,THR
referenced by chem comp atom: HG21,THR
referenced by chem comp atom: HG22,THR
referenced by chem comp atom: HG23,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: C,O,THR
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR
referenced by chem comp bond: CG2,HG23,THR
referenced by entity poly seq: 1,THR,18
referenced by entity poly seq: 1,THR,30
referenced by entity poly seq: 1,THR,43
referenced by entity poly seq: 1,THR,45
referenced by entity poly seq: 1,THR,51
referenced by entity poly seq: 1,THR,76
referenced by entity poly seq: 1,THR,101
referenced by entity poly seq: 1,THR,141
referenced by entity poly seq: 1,THR,162
referenced by entity poly seq: 1,THR,169
referenced by entity poly seq: 1,THR,186
referenced by entity poly seq: 1,THR,202
referenced by entity poly seq: 1,THR,222
referenced by entity poly seq: 1,THR,225
referenced by entity poly seq: 1,THR,235
referenced by entity poly seq: 1,THR,294
referenced by entity poly seq: 2,THR,10
referenced by entity poly seq: 2,THR,33
referenced by entity poly seq: 2,THR,57
referenced by entity poly seq: 2,THR,84
referenced by entity poly seq: 2,THR,108
referenced by entity poly seq: 2,THR,111
referenced by entity poly seq: 2,THR,113
referenced by entity poly seq: 2,THR,129
referenced by entity poly seq: 2,THR,136
referenced by entity poly seq: 2,THR,142
referenced by entity poly seq: 2,THR,192
referenced by entity poly seq: 2,THR,194
referenced by entity poly seq: 2,THR,206
referenced by entity poly seq: 2,THR,209
referenced by entity poly seq: 2,THR,223

TPO
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: TPO
chem comp.formula: C4 H10 N O6 P
chem comp.formula weight: 199.099
chem comp.mon nstd flag: n
chem comp.name: PHOSPHOTHREONINE
chem comp.pdbx synonyms: PHOSPHONOTHREONINE
chem comp.type: L-peptide linking
link to chem comp: TPO
referenced by chem comp atom: HXT,TPO
referenced by chem comp bond: OXT,HXT,TPO
referenced by entity poly seq: 1,TPO,164
referenced by chem comp atom: N,TPO
referenced by chem comp atom: CA,TPO
referenced by chem comp atom: CB,TPO
referenced by chem comp atom: CG2,TPO
referenced by chem comp atom: OG1,TPO
referenced by chem comp atom: P,TPO
referenced by chem comp atom: O1P,TPO
referenced by chem comp atom: O2P,TPO
referenced by chem comp atom: O3P,TPO
referenced by chem comp atom: C,TPO
referenced by chem comp atom: O,TPO
referenced by chem comp atom: OXT,TPO
referenced by chem comp atom: H,TPO
referenced by chem comp atom: H2,TPO
referenced by chem comp atom: HA,TPO
referenced by chem comp atom: HB,TPO
referenced by chem comp atom: HG21,TPO
referenced by chem comp atom: HG22,TPO
referenced by chem comp atom: HG23,TPO
referenced by chem comp atom: HOP2,TPO
referenced by chem comp atom: HOP3,TPO
referenced by chem comp bond: N,CA,TPO
referenced by chem comp bond: N,H,TPO
referenced by chem comp bond: N,H2,TPO
referenced by chem comp bond: CA,CB,TPO
referenced by chem comp bond: CA,C,TPO
referenced by chem comp bond: CA,HA,TPO
referenced by chem comp bond: CB,CG2,TPO
referenced by chem comp bond: CB,OG1,TPO
referenced by chem comp bond: CB,HB,TPO
referenced by chem comp bond: CG2,HG21,TPO
referenced by chem comp bond: CG2,HG22,TPO
referenced by chem comp bond: CG2,HG23,TPO
referenced by chem comp bond: OG1,P,TPO
referenced by chem comp bond: P,O1P,TPO
referenced by chem comp bond: P,O2P,TPO
referenced by chem comp bond: P,O3P,TPO
referenced by chem comp bond: O2P,HOP2,TPO
referenced by chem comp bond: O3P,HOP3,TPO
referenced by chem comp bond: C,O,TPO
referenced by chem comp bond: C,OXT,TPO

TRP
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: TRP
chem comp.formula: C11 H12 N2 O2
chem comp.formula weight: 204.225
chem comp.mon nstd flag: y
chem comp.name: TRYPTOPHAN
chem comp.type: L-peptide linking
link to chem comp: TRP
referenced by chem comp atom: HXT,TRP
referenced by chem comp bond: OXT,HXT,TRP
referenced by entity poly seq: 2,TRP,198
referenced by chem comp atom: N,TRP
referenced by chem comp atom: CA,TRP
referenced by chem comp atom: C,TRP
referenced by chem comp atom: O,TRP
referenced by chem comp atom: CB,TRP
referenced by chem comp atom: CG,TRP
referenced by chem comp atom: CD1,TRP
referenced by chem comp atom: CD2,TRP
referenced by chem comp atom: NE1,TRP
referenced by chem comp atom: CE2,TRP
referenced by chem comp atom: CE3,TRP
referenced by chem comp atom: CZ2,TRP
referenced by chem comp atom: CZ3,TRP
referenced by chem comp atom: CH2,TRP
referenced by chem comp atom: OXT,TRP
referenced by chem comp atom: H,TRP
referenced by chem comp atom: H2,TRP
referenced by chem comp atom: HA,TRP
referenced by chem comp atom: HB2,TRP
referenced by chem comp atom: HB3,TRP
referenced by chem comp atom: HD1,TRP
referenced by chem comp atom: HE1,TRP
referenced by chem comp atom: HE3,TRP
referenced by chem comp atom: HZ2,TRP
referenced by chem comp atom: HZ3,TRP
referenced by chem comp atom: HH2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: C,O,TRP
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CD2,CE2,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CZ2,CH2,TRP
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CH2,HH2,TRP
referenced by entity poly seq: 1,TRP,171
referenced by entity poly seq: 1,TRP,191
referenced by entity poly seq: 1,TRP,231
referenced by entity poly seq: 1,TRP,247
referenced by entity poly seq: 2,TRP,43

TYR
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: TYR
chem comp.formula: C9 H11 N O3
chem comp.formula weight: 181.189
chem comp.mon nstd flag: y
chem comp.name: TYROSINE
chem comp.type: L-peptide linking
link to chem comp: TYR
referenced by chem comp atom: HXT,TYR
referenced by chem comp bond: OXT,HXT,TYR
referenced by entity poly seq: 2,TYR,244
referenced by chem comp atom: N,TYR
referenced by chem comp atom: CA,TYR
referenced by chem comp atom: C,TYR
referenced by chem comp atom: O,TYR
referenced by chem comp atom: CB,TYR
referenced by chem comp atom: CG,TYR
referenced by chem comp atom: CD1,TYR
referenced by chem comp atom: CD2,TYR
referenced by chem comp atom: CE1,TYR
referenced by chem comp atom: CE2,TYR
referenced by chem comp atom: CZ,TYR
referenced by chem comp atom: OH,TYR
referenced by chem comp atom: OXT,TYR
referenced by chem comp atom: H,TYR
referenced by chem comp atom: H2,TYR
referenced by chem comp atom: HA,TYR
referenced by chem comp atom: HB2,TYR
referenced by chem comp atom: HB3,TYR
referenced by chem comp atom: HD1,TYR
referenced by chem comp atom: HD2,TYR
referenced by chem comp atom: HE1,TYR
referenced by chem comp atom: HE2,TYR
referenced by chem comp atom: HH,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: C,O,TYR
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CE1,CZ,TYR
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: OH,HH,TYR
referenced by entity poly seq: 1,TYR,19
referenced by entity poly seq: 1,TYR,23
referenced by entity poly seq: 1,TYR,81
referenced by entity poly seq: 1,TYR,111
referenced by entity poly seq: 1,TYR,163
referenced by entity poly seq: 1,TYR,172
referenced by entity poly seq: 1,TYR,183
referenced by entity poly seq: 1,TYR,184
referenced by entity poly seq: 1,TYR,240
referenced by entity poly seq: 1,TYR,273
referenced by entity poly seq: 2,TYR,4
referenced by entity poly seq: 2,TYR,11
referenced by entity poly seq: 2,TYR,25
referenced by entity poly seq: 2,TYR,51
referenced by entity poly seq: 2,TYR,64
referenced by entity poly seq: 2,TYR,97
referenced by entity poly seq: 2,TYR,106
referenced by entity poly seq: 2,TYR,112
referenced by entity poly seq: 2,TYR,144
referenced by entity poly seq: 2,TYR,173
referenced by entity poly seq: 2,TYR,176
referenced by entity poly seq: 2,TYR,191

VAL
type: chem comp
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
chem comp.id: VAL
chem comp.formula: C5 H11 N O2
chem comp.formula weight: 117.146
chem comp.mon nstd flag: y
chem comp.name: VALINE
chem comp.type: L-peptide linking
link to chem comp: VAL
referenced by chem comp atom: HXT,VAL
referenced by chem comp bond: OXT,HXT,VAL
referenced by entity poly seq: 2,VAL,247
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/15
referenced by chem comp atom: N,VAL
referenced by chem comp atom: CA,VAL
referenced by chem comp atom: C,VAL
referenced by chem comp atom: O,VAL
referenced by chem comp atom: CB,VAL
referenced by chem comp atom: CG1,VAL
referenced by chem comp atom: CG2,VAL
referenced by chem comp atom: OXT,VAL
referenced by chem comp atom: H,VAL
referenced by chem comp atom: H2,VAL
referenced by chem comp atom: HA,VAL
referenced by chem comp atom: HB,VAL
referenced by chem comp atom: HG11,VAL
referenced by chem comp atom: HG12,VAL
referenced by chem comp atom: HG13,VAL
referenced by chem comp atom: HG21,VAL
referenced by chem comp atom: HG22,VAL
referenced by chem comp atom: HG23,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: C,O,VAL
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL
referenced by chem comp bond: CG2,HG23,VAL
referenced by entity poly seq: 1,VAL,11
referenced by entity poly seq: 1,VAL,21
referenced by entity poly seq: 1,VAL,22
referenced by entity poly seq: 1,VAL,33
referenced by entity poly seq: 1,VAL,34
referenced by entity poly seq: 1,VAL,48
referenced by entity poly seq: 1,VAL,68
referenced by entity poly seq: 1,VAL,73
referenced by entity poly seq: 1,VAL,83
referenced by entity poly seq: 1,VAL,127
referenced by entity poly seq: 1,VAL,158
referenced by entity poly seq: 1,VAL,160
referenced by entity poly seq: 1,VAL,167
referenced by entity poly seq: 1,VAL,168
referenced by entity poly seq: 1,VAL,188
referenced by entity poly seq: 1,VAL,201
referenced by entity poly seq: 1,VAL,229
referenced by entity poly seq: 1,VAL,230
referenced by entity poly seq: 1,VAL,234
referenced by entity poly seq: 1,VAL,255
referenced by entity poly seq: 1,VAL,256
referenced by entity poly seq: 1,VAL,293
referenced by entity poly seq: 1,VAL,297
referenced by entity poly seq: 2,VAL,1
referenced by entity poly seq: 2,VAL,17
referenced by entity poly seq: 2,VAL,23
referenced by entity poly seq: 2,VAL,41
referenced by entity poly seq: 2,VAL,45
referenced by entity poly seq: 2,VAL,47
referenced by entity poly seq: 2,VAL,62
referenced by entity poly seq: 2,VAL,74
referenced by entity poly seq: 2,VAL,82

N,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: N
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 1
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: N,H,ALA

CA,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: CA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 2
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ALA
referenced by chem comp bond: N,CA,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: CA,CB,ALA

C,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: C
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 3
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ALA
referenced by chem comp bond: CA,C,ALA
referenced by chem comp bond: C,O,ALA

O,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: O
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 4
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ALA

CB,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: CB
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 5
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ALA
referenced by chem comp bond: CA,CB,ALA
referenced by chem comp bond: CB,HB1,ALA
referenced by chem comp bond: CB,HB2,ALA

OXT,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: OXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 6
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ALA
referenced by chem comp bond: C,OXT,ALA

H,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: H
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 7
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ALA

H2,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: H2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 8
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ALA

HA,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: HA
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 9
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ALA

HB1,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: HB1
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 10
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB1,ALA

HB2,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: HB2
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 11
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ALA

HB3,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: HB3
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 12
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ALA

HXT,ALA
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
chem comp atom.atom id: HXT
chem comp atom.comp id: ALA
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 13
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ALA

N,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: N
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 14
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: N,H,ARG

CA,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: CA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 15
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ARG
referenced by chem comp bond: N,CA,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: CA,CB,ARG

C,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: C
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 16
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ARG
referenced by chem comp bond: CA,C,ARG
referenced by chem comp bond: C,O,ARG

O,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: O
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 17
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ARG

CB,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: CB
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 18
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ARG
referenced by chem comp bond: CA,CB,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CB,HB2,ARG

CG,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: CG
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 19
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,ARG
referenced by chem comp bond: CB,CG,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CG,HG2,ARG

CD,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: CD
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 20
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,ARG
referenced by chem comp bond: CG,CD,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: CD,HD2,ARG

NE,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: NE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 21
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE,HE,ARG
referenced by chem comp bond: CD,NE,ARG
referenced by chem comp bond: NE,CZ,ARG

CZ,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: CZ
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 22
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NE,CZ,ARG
referenced by chem comp bond: CZ,NH1,ARG

NH1,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: NH1
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 23
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH1,HH12,ARG
referenced by chem comp bond: CZ,NH1,ARG
referenced by chem comp bond: NH1,HH11,ARG

NH2,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: NH2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 24
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NH2,HH22,ARG
referenced by chem comp bond: CZ,NH2,ARG
referenced by chem comp bond: NH2,HH21,ARG

OXT,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: OXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 25
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ARG
referenced by chem comp bond: C,OXT,ARG

H,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: H
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 26
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ARG

H2,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: H2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 27
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ARG

HA,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HA
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 28
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ARG

HB2,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HB2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 29
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ARG

HB3,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HB3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 30
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ARG

HG2,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HG2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 31
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,ARG

HG3,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HG3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 32
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,ARG

HD2,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HD2
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 33
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,ARG

HD3,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HD3
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 34
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,ARG

HE,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HE
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 35
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE,HE,ARG

HH11,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HH11
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 36
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH11,ARG

HH12,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HH12
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 37
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH1,HH12,ARG

HH21,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HH21
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 38
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH21,ARG

HH22,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HH22
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 39
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NH2,HH22,ARG

HXT,ARG
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
chem comp atom.atom id: HXT
chem comp atom.comp id: ARG
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 40
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ARG

N,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: N
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 41
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: N,H,ASN

CA,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: CA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 42
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASN
referenced by chem comp bond: N,CA,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: CA,CB,ASN

C,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: C
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 43
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASN
referenced by chem comp bond: CA,C,ASN
referenced by chem comp bond: C,O,ASN

O,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: O
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 44
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASN

CB,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: CB
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 45
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASN
referenced by chem comp bond: CA,CB,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CB,HB2,ASN

CG,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: CG
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 46
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: CB,CG,ASN
referenced by chem comp bond: CG,OD1,ASN

OD1,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: OD1
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 47
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASN

ND2,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: ND2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 48
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND2,HD22,ASN
referenced by chem comp bond: CG,ND2,ASN
referenced by chem comp bond: ND2,HD21,ASN

OXT,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: OXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 49
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASN
referenced by chem comp bond: C,OXT,ASN

H,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: H
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 50
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASN

H2,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: H2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 51
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASN

HA,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HA
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 52
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASN

HB2,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HB2
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 53
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASN

HB3,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HB3
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 54
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASN

HD21,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HD21
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 55
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD21,ASN

HD22,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HD22
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 56
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND2,HD22,ASN

HXT,ASN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
chem comp atom.atom id: HXT
chem comp atom.comp id: ASN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 57
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASN

N,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: N
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 58
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: N,H,ASP

CA,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: CA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 59
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ASP
referenced by chem comp bond: N,CA,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: CA,CB,ASP

C,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: C
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 60
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ASP
referenced by chem comp bond: CA,C,ASP
referenced by chem comp bond: C,O,ASP

O,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: O
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 61
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ASP

CB,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: CB
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 62
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,ASP
referenced by chem comp bond: CA,CB,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CB,HB2,ASP

CG,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: CG
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 63
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,OD2,ASP
referenced by chem comp bond: CB,CG,ASP
referenced by chem comp bond: CG,OD1,ASP

OD1,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: OD1
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 64
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CG,OD1,ASP

OD2,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: OD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 65
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OD2,HD2,ASP
referenced by chem comp bond: CG,OD2,ASP

OXT,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: OXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 66
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ASP
referenced by chem comp bond: C,OXT,ASP

H,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: H
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 67
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ASP

H2,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: H2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 68
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ASP

HA,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: HA
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 69
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ASP

HB2,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: HB2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 70
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,ASP

HB3,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: HB3
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 71
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,ASP

HD2,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: HD2
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 72
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OD2,HD2,ASP

HXT,ASP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
chem comp atom.atom id: HXT
chem comp atom.comp id: ASP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 73
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ASP

N,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: N
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 74
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: N,H,CYS

CA,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: CA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 75
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,CYS
referenced by chem comp bond: N,CA,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: CA,CB,CYS

C,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: C
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 76
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,CYS
referenced by chem comp bond: CA,C,CYS
referenced by chem comp bond: C,O,CYS

O,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: O
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 77
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,CYS

CB,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: CB
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 78
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,CYS
referenced by chem comp bond: CA,CB,CYS
referenced by chem comp bond: CB,SG,CYS
referenced by chem comp bond: CB,HB2,CYS

SG,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: SG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 79
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SG,HG,CYS
referenced by chem comp bond: CB,SG,CYS

OXT,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: OXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 80
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,CYS
referenced by chem comp bond: C,OXT,CYS

H,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: H
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 81
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,CYS

H2,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: H2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 82
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,CYS

HA,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: HA
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 83
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,CYS

HB2,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: HB2
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 84
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,CYS

HB3,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: HB3
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 85
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,CYS

HG,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: HG
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 86
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: SG,HG,CYS

HXT,CYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
chem comp atom.atom id: HXT
chem comp atom.comp id: CYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 87
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,CYS

S1,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: S1
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 88
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: S1,HS1,DTT
referenced by chem comp bond: S1,C1,DTT

C1,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: C1
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 89
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C1,H12,DTT
referenced by chem comp bond: S1,C1,DTT
referenced by chem comp bond: C1,C2,DTT
referenced by chem comp bond: C1,H11,DTT

C2,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: C2
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 90
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: C2,H2,DTT
referenced by chem comp bond: C1,C2,DTT
referenced by chem comp bond: C2,O2,DTT
referenced by chem comp bond: C2,C3,DTT

O2,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: O2
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 91
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O2,HO2,DTT
referenced by chem comp bond: C2,O2,DTT

C3,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: C3
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 92
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: C3,H3,DTT
referenced by chem comp bond: C2,C3,DTT
referenced by chem comp bond: C3,O3,DTT
referenced by chem comp bond: C3,C4,DTT

O3,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: O3
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 93
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O3,HO3,DTT
referenced by chem comp bond: C3,O3,DTT

C4,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: C4
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 94
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C4,H42,DTT
referenced by chem comp bond: C3,C4,DTT
referenced by chem comp bond: C4,S4,DTT
referenced by chem comp bond: C4,H41,DTT

S4,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: S4
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 95
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: S4,HS2,DTT
referenced by chem comp bond: C4,S4,DTT

HS1,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: HS1
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 96
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: S1,HS1,DTT

H11,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H11
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 97
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H11,DTT

H12,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H12
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 98
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C1,H12,DTT

H2,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H2
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 99
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C2,H2,DTT

HO2,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: HO2
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 100
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O2,HO2,DTT

H3,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H3
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 101
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C3,H3,DTT

HO3,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: HO3
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 102
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O3,HO3,DTT

H41,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H41
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 103
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C4,H41,DTT

H42,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: H42
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 104
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: C4,H42,DTT

HS2,DTT
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: DTT
chem comp atom.atom id: HS2
chem comp atom.comp id: DTT
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 105
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: S4,HS2,DTT

N,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: N
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 106
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: N,H,GLN

CA,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: CA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 107
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLN
referenced by chem comp bond: N,CA,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: CA,CB,GLN

C,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: C
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 108
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLN
referenced by chem comp bond: CA,C,GLN
referenced by chem comp bond: C,O,GLN

O,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: O
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 109
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLN

CB,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: CB
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 110
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLN
referenced by chem comp bond: CA,CB,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CB,HB2,GLN

CG,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: CG
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 111
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLN
referenced by chem comp bond: CB,CG,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CG,HG2,GLN

CD,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: CD
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 112
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: CG,CD,GLN
referenced by chem comp bond: CD,OE1,GLN

OE1,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: OE1
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 113
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLN

NE2,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: NE2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 114
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE22,GLN
referenced by chem comp bond: CD,NE2,GLN
referenced by chem comp bond: NE2,HE21,GLN

OXT,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: OXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 115
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLN
referenced by chem comp bond: C,OXT,GLN

H,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: H
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 116
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLN

H2,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: H2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 117
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLN

HA,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HA
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 118
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLN

HB2,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HB2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 119
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLN

HB3,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HB3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 120
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLN

HG2,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HG2
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 121
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLN

HG3,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HG3
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 122
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLN

HE21,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HE21
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 123
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE21,GLN

HE22,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HE22
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 124
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE22,GLN

HXT,GLN
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
chem comp atom.atom id: HXT
chem comp atom.comp id: GLN
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 125
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLN

N,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: N
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 126
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: N,H,GLU

CA,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: CA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 127
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,GLU
referenced by chem comp bond: N,CA,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: CA,CB,GLU

C,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: C
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 128
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLU
referenced by chem comp bond: CA,C,GLU
referenced by chem comp bond: C,O,GLU

O,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: O
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 129
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLU

CB,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: CB
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 130
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,GLU
referenced by chem comp bond: CA,CB,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CB,HB2,GLU

CG,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: CG
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 131
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,GLU
referenced by chem comp bond: CB,CG,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CG,HG2,GLU

CD,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: CD
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 132
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,OE2,GLU
referenced by chem comp bond: CG,CD,GLU
referenced by chem comp bond: CD,OE1,GLU

OE1,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: OE1
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 133
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: CD,OE1,GLU

OE2,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: OE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 134
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OE2,HE2,GLU
referenced by chem comp bond: CD,OE2,GLU

OXT,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: OXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 135
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLU
referenced by chem comp bond: C,OXT,GLU

H,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: H
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 136
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLU

H2,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: H2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 137
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLU

HA,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HA
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 138
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,GLU

HB2,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HB2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 139
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,GLU

HB3,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HB3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 140
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,GLU

HG2,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HG2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 141
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,GLU

HG3,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HG3
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 142
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,GLU

HE2,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HE2
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 143
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OE2,HE2,GLU

HXT,GLU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
chem comp atom.atom id: HXT
chem comp atom.comp id: GLU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 144
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLU

N,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: N
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 145
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: N,H,GLY

CA,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: CA
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 146
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA3,GLY
referenced by chem comp bond: N,CA,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: CA,HA2,GLY

C,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: C
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 147
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,GLY
referenced by chem comp bond: CA,C,GLY
referenced by chem comp bond: C,O,GLY

O,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: O
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 148
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,GLY

OXT,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: OXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 149
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,GLY
referenced by chem comp bond: C,OXT,GLY

H,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: H
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 150
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,GLY

H2,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: H2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 151
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,GLY

HA2,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: HA2
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 152
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA2,GLY

HA3,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: HA3
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 153
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA3,GLY

HXT,GLY
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
chem comp atom.atom id: HXT
chem comp atom.comp id: GLY
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 154
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,GLY

N,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: N
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 155
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: N,H,HIS

CA,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: CA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 156
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,HIS
referenced by chem comp bond: N,CA,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: CA,CB,HIS

C,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: C
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 157
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,HIS
referenced by chem comp bond: CA,C,HIS
referenced by chem comp bond: C,O,HIS

O,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: O
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 158
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,HIS

CB,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: CB
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 159
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,HIS
referenced by chem comp bond: CA,CB,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CB,HB2,HIS

CG,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: CG
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 160
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CB,CG,HIS
referenced by chem comp bond: CG,ND1,HIS

ND1,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: ND1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 161
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: ND1,HD1,HIS
referenced by chem comp bond: CG,ND1,HIS
referenced by chem comp bond: ND1,CE1,HIS

CD2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: CD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 162
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,HIS
referenced by chem comp bond: CG,CD2,HIS
referenced by chem comp bond: CD2,NE2,HIS

CE1,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: CE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 163
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,HIS
referenced by chem comp bond: ND1,CE1,HIS
referenced by chem comp bond: CE1,NE2,HIS

NE2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: NE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 164
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE2,HE2,HIS
referenced by chem comp bond: CE1,NE2,HIS
referenced by chem comp bond: CD2,NE2,HIS

OXT,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: OXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 165
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,HIS
referenced by chem comp bond: C,OXT,HIS

H,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: H
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 166
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,HIS

H2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: H2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 167
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,HIS

HA,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HA
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 168
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,HIS

HB2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HB2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 169
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,HIS

HB3,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HB3
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 170
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,HIS

HD1,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HD1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 171
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: ND1,HD1,HIS

HD2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HD2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 172
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,HIS

HE1,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HE1
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 173
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,HIS

HE2,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HE2
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 174
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE2,HE2,HIS

HXT,HIS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
chem comp atom.atom id: HXT
chem comp atom.comp id: HIS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 175
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,HIS

O,HOH
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HOH
chem comp atom.atom id: O
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 176
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O,H2,HOH
referenced by chem comp bond: O,H1,HOH

H1,HOH
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HOH
chem comp atom.atom id: H1
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 177
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H1,HOH

H2,HOH
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HOH
chem comp atom.atom id: H2
chem comp atom.comp id: HOH
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 178
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O,H2,HOH

N,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: N
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 179
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: N,H,ILE

CA,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: CA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 180
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,ILE
referenced by chem comp bond: N,CA,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: CA,CB,ILE

C,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: C
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 181
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,ILE
referenced by chem comp bond: CA,C,ILE
referenced by chem comp bond: C,O,ILE

O,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: O
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 182
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,ILE

CB,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: CB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 183
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,ILE
referenced by chem comp bond: CA,CB,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CB,CG2,ILE

CG1,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: CG1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 184
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,ILE
referenced by chem comp bond: CB,CG1,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CG1,HG12,ILE

CG2,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: CG2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 185
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,ILE
referenced by chem comp bond: CB,CG2,ILE
referenced by chem comp bond: CG2,HG21,ILE
referenced by chem comp bond: CG2,HG22,ILE

CD1,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: CD1
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 186
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,ILE
referenced by chem comp bond: CG1,CD1,ILE
referenced by chem comp bond: CD1,HD11,ILE
referenced by chem comp bond: CD1,HD12,ILE

OXT,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: OXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 187
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,ILE
referenced by chem comp bond: C,OXT,ILE

H,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: H
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 188
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,ILE

H2,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: H2
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 189
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,ILE

HA,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HA
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 190
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,ILE

HB,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HB
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 191
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,ILE

HG12,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HG12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 192
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,ILE

HG13,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HG13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 193
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,ILE

HG21,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HG21
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 194
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,ILE

HG22,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HG22
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 195
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,ILE

HG23,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HG23
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 196
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,ILE

HD11,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HD11
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 197
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,ILE

HD12,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HD12
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 198
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,ILE

HD13,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HD13
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 199
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,ILE

HXT,ILE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
chem comp atom.atom id: HXT
chem comp atom.comp id: ILE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 200
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,ILE

FAT,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: FAT
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 201
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: F
referenced by chem comp bond: FAT,CAS,JYM

CAS,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAS
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 202
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAS,C8,JYM
referenced by chem comp bond: FAT,CAS,JYM
referenced by chem comp bond: CAS,FAU,JYM
referenced by chem comp bond: CAS,FAV,JYM

FAU,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: FAU
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 203
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: F
referenced by chem comp bond: CAS,FAU,JYM

FAV,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: FAV
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 204
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: F
referenced by chem comp bond: CAS,FAV,JYM

C8,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: C8
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 205
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C8,N7,JYM
referenced by chem comp bond: CAS,C8,JYM
referenced by chem comp bond: C8,N9,JYM

N9,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: N9
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 206
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N9,H9,JYM
referenced by chem comp bond: C8,N9,JYM
referenced by chem comp bond: N9,C4,JYM

N7,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: N7
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 207
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N7,C5,JYM
referenced by chem comp bond: C8,N7,JYM

C5,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: C5
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 208
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C5,C6,JYM
referenced by chem comp bond: N7,C5,JYM
referenced by chem comp bond: C5,C4,JYM

C4,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: C4
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 209
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C4,N3,JYM
referenced by chem comp bond: C5,C4,JYM
referenced by chem comp bond: N9,C4,JYM

N3,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: N3
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 210
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N3,C2,JYM
referenced by chem comp bond: C4,N3,JYM

C2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: C2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 211
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C2,N1,JYM
referenced by chem comp bond: N3,C2,JYM
referenced by chem comp bond: C2,N2,JYM

N2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: N2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 212
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N2,H22N,JYM
referenced by chem comp bond: C2,N2,JYM
referenced by chem comp bond: N2,H21N,JYM

N1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: N1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 213
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N1,C6,JYM
referenced by chem comp bond: C2,N1,JYM

C6,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: C6
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 214
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C6,O6,JYM
referenced by chem comp bond: N1,C6,JYM
referenced by chem comp bond: C5,C6,JYM

O6,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: O6
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 215
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O6,CAL,JYM
referenced by chem comp bond: C6,O6,JYM

CAL,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAL
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 216
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAL,HAL2,JYM
referenced by chem comp bond: O6,CAL,JYM
referenced by chem comp bond: CAL,CAM,JYM
referenced by chem comp bond: CAL,HAL1,JYM

CAM,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAM
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 217
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAM,HAM,JYM
referenced by chem comp bond: CAL,CAM,JYM
referenced by chem comp bond: CAM,CAN,JYM
referenced by chem comp bond: CAM,CAR,JYM

CAN,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAN
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 218
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAN,HAN2,JYM
referenced by chem comp bond: CAM,CAN,JYM
referenced by chem comp bond: CAN,CAO,JYM
referenced by chem comp bond: CAN,HAN1,JYM

CAO,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAO
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 219
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAO,HAO2,JYM
referenced by chem comp bond: CAN,CAO,JYM
referenced by chem comp bond: CAO,CAP,JYM
referenced by chem comp bond: CAO,HAO1,JYM

CAP,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAP
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 220
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAP,HAP2,JYM
referenced by chem comp bond: CAO,CAP,JYM
referenced by chem comp bond: CAP,CAQ,JYM
referenced by chem comp bond: CAP,HAP1,JYM

CAQ,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAQ
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 221
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAQ,HAQ2,JYM
referenced by chem comp bond: CAP,CAQ,JYM
referenced by chem comp bond: CAQ,CAR,JYM
referenced by chem comp bond: CAQ,HAQ1,JYM

CAR,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: CAR
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 222
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CAR,HAR2,JYM
referenced by chem comp bond: CAQ,CAR,JYM
referenced by chem comp bond: CAM,CAR,JYM
referenced by chem comp bond: CAR,HAR1,JYM

H9,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: H9
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 223
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N9,H9,JYM

H21N,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: H21N
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 224
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N2,H21N,JYM

H22N,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: H22N
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 225
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N2,H22N,JYM

HAL1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAL1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 226
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAL,HAL1,JYM

HAL2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAL2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 227
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAL,HAL2,JYM

HAM,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAM
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 228
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAM,HAM,JYM

HAN1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAN1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 229
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAN,HAN1,JYM

HAN2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAN2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 230
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAN,HAN2,JYM

HAR1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAR1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 231
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAR,HAR1,JYM

HAR2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAR2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 232
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAR,HAR2,JYM

HAO1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAO1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 233
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAO,HAO1,JYM

HAO2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAO2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 234
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAO,HAO2,JYM

HAP1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAP1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 235
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAP,HAP1,JYM

HAP2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAP2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 236
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAP,HAP2,JYM

HAQ1,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAQ1
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 237
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAQ,HAQ1,JYM

HAQ2,JYM
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: JYM
chem comp atom.atom id: HAQ2
chem comp atom.comp id: JYM
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 238
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CAQ,HAQ2,JYM

N,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: N
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 239
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: N,H,LEU

CA,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: CA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 240
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LEU
referenced by chem comp bond: N,CA,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: CA,CB,LEU

C,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: C
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 241
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LEU
referenced by chem comp bond: CA,C,LEU
referenced by chem comp bond: C,O,LEU

O,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: O
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 242
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LEU

CB,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: CB
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 243
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LEU
referenced by chem comp bond: CA,CB,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CB,HB2,LEU

CG,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: CG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 244
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG,LEU
referenced by chem comp bond: CB,CG,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CG,CD2,LEU

CD1,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: CD1
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 245
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD13,LEU
referenced by chem comp bond: CG,CD1,LEU
referenced by chem comp bond: CD1,HD11,LEU
referenced by chem comp bond: CD1,HD12,LEU

CD2,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: CD2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 246
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD23,LEU
referenced by chem comp bond: CG,CD2,LEU
referenced by chem comp bond: CD2,HD21,LEU
referenced by chem comp bond: CD2,HD22,LEU

OXT,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: OXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 247
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LEU
referenced by chem comp bond: C,OXT,LEU

H,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: H
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 248
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LEU

H2,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: H2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 249
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LEU

HA,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HA
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 250
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LEU

HB2,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HB2
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 251
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LEU

HB3,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HB3
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 252
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LEU

HG,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HG
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 253
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG,LEU

HD11,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD11
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 254
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD11,LEU

HD12,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD12
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 255
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD12,LEU

HD13,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD13
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 256
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD13,LEU

HD21,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD21
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 257
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD21,LEU

HD22,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD22
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 258
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD22,LEU

HD23,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HD23
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 259
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD23,LEU

HXT,LEU
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
chem comp atom.atom id: HXT
chem comp atom.comp id: LEU
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 260
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LEU

N,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: N
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 261
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: N,H,LYS

CA,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: CA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 262
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,LYS
referenced by chem comp bond: N,CA,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: CA,CB,LYS

C,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: C
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 263
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,LYS
referenced by chem comp bond: CA,C,LYS
referenced by chem comp bond: C,O,LYS

O,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: O
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 264
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,LYS

CB,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: CB
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 265
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,LYS
referenced by chem comp bond: CA,CB,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CB,HB2,LYS

CG,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: CG
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 266
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,LYS
referenced by chem comp bond: CB,CG,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CG,HG2,LYS

CD,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: CD
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 267
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,LYS
referenced by chem comp bond: CG,CD,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CD,HD2,LYS

CE,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: CE
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 268
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,LYS
referenced by chem comp bond: CD,CE,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: CE,HE2,LYS

NZ,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: NZ
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 269
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NZ,HZ3,LYS
referenced by chem comp bond: CE,NZ,LYS
referenced by chem comp bond: NZ,HZ1,LYS
referenced by chem comp bond: NZ,HZ2,LYS

OXT,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: OXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 270
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,LYS
referenced by chem comp bond: C,OXT,LYS

H,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: H
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 271
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,LYS

H2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: H2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 272
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,LYS

HA,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HA
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 273
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,LYS

HB2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HB2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 274
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,LYS

HB3,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HB3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 275
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,LYS

HG2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HG2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 276
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,LYS

HG3,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HG3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 277
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,LYS

HD2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HD2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 278
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,LYS

HD3,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HD3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 279
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,LYS

HE2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HE2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 280
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,LYS

HE3,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HE3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 281
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,LYS

HZ1,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HZ1
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 282
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ1,LYS

HZ2,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HZ2
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 283
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ2,LYS

HZ3,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HZ3
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 284
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NZ,HZ3,LYS

HXT,LYS
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
chem comp atom.atom id: HXT
chem comp atom.comp id: LYS
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 285
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,LYS

N,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: N
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 286
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: N,H,MET

CA,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: CA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 287
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,MET
referenced by chem comp bond: N,CA,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: CA,CB,MET

C,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: C
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 288
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,MET
referenced by chem comp bond: CA,C,MET
referenced by chem comp bond: C,O,MET

O,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: O
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 289
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,MET

CB,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: CB
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 290
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,MET
referenced by chem comp bond: CA,CB,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CB,HB2,MET

CG,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: CG
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 291
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,MET
referenced by chem comp bond: CB,CG,MET
referenced by chem comp bond: CG,SD,MET
referenced by chem comp bond: CG,HG2,MET

SD,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: SD
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 292
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: S
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CG,SD,MET

CE,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: CE
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 293
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE,HE3,MET
referenced by chem comp bond: SD,CE,MET
referenced by chem comp bond: CE,HE1,MET
referenced by chem comp bond: CE,HE2,MET

OXT,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: OXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 294
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,MET
referenced by chem comp bond: C,OXT,MET

H,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: H
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 295
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,MET

H2,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: H2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 296
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,MET

HA,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HA
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 297
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,MET

HB2,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HB2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 298
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,MET

HB3,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HB3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 299
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,MET

HG2,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HG2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 300
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,MET

HG3,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HG3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 301
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,MET

HE1,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HE1
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 302
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE1,MET

HE2,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HE2
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 303
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE2,MET

HE3,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HE3
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 304
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE,HE3,MET

HXT,MET
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
chem comp atom.atom id: HXT
chem comp atom.comp id: MET
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 305
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,MET

N,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: N
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 306
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: N,H,PHE

CA,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 307
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PHE
referenced by chem comp bond: N,CA,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: CA,CB,PHE

C,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: C
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 308
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PHE
referenced by chem comp bond: CA,C,PHE
referenced by chem comp bond: C,O,PHE

O,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: O
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 309
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PHE

CB,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CB
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 310
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PHE
referenced by chem comp bond: CA,CB,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CB,HB2,PHE

CG,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CG
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 311
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CB,CG,PHE
referenced by chem comp bond: CG,CD1,PHE

CD1,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 312
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,PHE
referenced by chem comp bond: CG,CD1,PHE
referenced by chem comp bond: CD1,CE1,PHE

CD2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 313
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,PHE
referenced by chem comp bond: CG,CD2,PHE
referenced by chem comp bond: CD2,CE2,PHE

CE1,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 314
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,PHE
referenced by chem comp bond: CD1,CE1,PHE
referenced by chem comp bond: CE1,CZ,PHE

CE2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 315
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,PHE
referenced by chem comp bond: CD2,CE2,PHE
referenced by chem comp bond: CE2,CZ,PHE

CZ,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: CZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 316
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,HZ,PHE
referenced by chem comp bond: CE2,CZ,PHE
referenced by chem comp bond: CE1,CZ,PHE

OXT,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: OXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 317
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PHE
referenced by chem comp bond: C,OXT,PHE

H,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: H
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 318
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PHE

H2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: H2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 319
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,PHE

HA,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HA
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 320
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PHE

HB2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HB2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 321
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PHE

HB3,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HB3
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 322
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PHE

HD1,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HD1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 323
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,PHE

HD2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HD2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 324
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,PHE

HE1,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HE1
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 325
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,PHE

HE2,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HE2
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 326
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,PHE

HZ,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HZ
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 327
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ,HZ,PHE

HXT,PHE
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
chem comp atom.atom id: HXT
chem comp atom.comp id: PHE
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 328
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PHE

N,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: N
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 329
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: N,CD,PRO

CA,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: CA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 330
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,PRO
referenced by chem comp bond: N,CA,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: CA,CB,PRO

C,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: C
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 331
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,PRO
referenced by chem comp bond: CA,C,PRO
referenced by chem comp bond: C,O,PRO

O,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: O
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 332
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,PRO

CB,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: CB
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 333
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,PRO
referenced by chem comp bond: CA,CB,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CB,HB2,PRO

CG,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: CG
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 334
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,HG3,PRO
referenced by chem comp bond: CB,CG,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: CG,HG2,PRO

CD,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: CD
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 335
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD,HD3,PRO
referenced by chem comp bond: CG,CD,PRO
referenced by chem comp bond: N,CD,PRO
referenced by chem comp bond: CD,HD2,PRO

OXT,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: OXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 336
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,PRO
referenced by chem comp bond: C,OXT,PRO

H,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: H
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 337
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,PRO

HA,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HA
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 338
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,PRO

HB2,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HB2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 339
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,PRO

HB3,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HB3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 340
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,PRO

HG2,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HG2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 341
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG2,PRO

HG3,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HG3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 342
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG,HG3,PRO

HD2,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HD2
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 343
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD2,PRO

HD3,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HD3
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 344
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD,HD3,PRO

HXT,PRO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
chem comp atom.atom id: HXT
chem comp atom.comp id: PRO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 345
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,PRO

N,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: N
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 346
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: N,H,SER

CA,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: CA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 347
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,SER
referenced by chem comp bond: N,CA,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: CA,CB,SER

C,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: C
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 348
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,SER
referenced by chem comp bond: CA,C,SER
referenced by chem comp bond: C,O,SER

O,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: O
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 349
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,SER

CB,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: CB
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 350
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,SER
referenced by chem comp bond: CA,CB,SER
referenced by chem comp bond: CB,OG,SER
referenced by chem comp bond: CB,HB2,SER

OG,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: OG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 351
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG,HG,SER
referenced by chem comp bond: CB,OG,SER

OXT,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: OXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 352
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,SER
referenced by chem comp bond: C,OXT,SER

H,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: H
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 353
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,SER

H2,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: H2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 354
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,SER

HA,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: HA
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 355
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,SER

HB2,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: HB2
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 356
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,SER

HB3,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: HB3
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 357
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,SER

HG,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: HG
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 358
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG,HG,SER

HXT,SER
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
chem comp atom.atom id: HXT
chem comp atom.comp id: SER
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 359
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,SER

N,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: N
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 360
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: N,H,THR

CA,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: CA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 361
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,THR
referenced by chem comp bond: N,CA,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: CA,CB,THR

C,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: C
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 362
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,THR
referenced by chem comp bond: CA,C,THR
referenced by chem comp bond: C,O,THR

O,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: O
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 363
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,THR

CB,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: CB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 364
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,THR
referenced by chem comp bond: CA,CB,THR
referenced by chem comp bond: CB,OG1,THR
referenced by chem comp bond: CB,CG2,THR

OG1,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: OG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 365
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG1,HG1,THR
referenced by chem comp bond: CB,OG1,THR

CG2,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: CG2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 366
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,THR
referenced by chem comp bond: CB,CG2,THR
referenced by chem comp bond: CG2,HG21,THR
referenced by chem comp bond: CG2,HG22,THR

OXT,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: OXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 367
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,THR
referenced by chem comp bond: C,OXT,THR

H,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: H
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 368
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,THR

H2,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: H2
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 369
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,THR

HA,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HA
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 370
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,THR

HB,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HB
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 371
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,THR

HG1,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HG1
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 372
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OG1,HG1,THR

HG21,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HG21
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 373
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,THR

HG22,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HG22
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 374
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,THR

HG23,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HG23
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 375
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,THR

HXT,THR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
chem comp atom.atom id: HXT
chem comp atom.comp id: THR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 376
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,THR

N,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: N
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 377
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TPO
referenced by chem comp bond: N,CA,TPO
referenced by chem comp bond: N,H,TPO

CA,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: CA
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 378
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TPO
referenced by chem comp bond: N,CA,TPO
referenced by chem comp bond: CA,CB,TPO
referenced by chem comp bond: CA,C,TPO

CB,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: CB
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 379
chem comp atom.pdbx stereo config: R
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,TPO
referenced by chem comp bond: CA,CB,TPO
referenced by chem comp bond: CB,CG2,TPO
referenced by chem comp bond: CB,OG1,TPO

CG2,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: CG2
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 380
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,TPO
referenced by chem comp bond: CB,CG2,TPO
referenced by chem comp bond: CG2,HG21,TPO
referenced by chem comp bond: CG2,HG22,TPO

OG1,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: OG1
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 381
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OG1,P,TPO
referenced by chem comp bond: CB,OG1,TPO

P,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: P
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 382
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: P
referenced by chem comp bond: P,O3P,TPO
referenced by chem comp bond: OG1,P,TPO
referenced by chem comp bond: P,O1P,TPO
referenced by chem comp bond: P,O2P,TPO

O1P,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: O1P
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 383
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: P,O1P,TPO

O2P,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: O2P
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 384
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O2P,HOP2,TPO
referenced by chem comp bond: P,O2P,TPO

O3P,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: O3P
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 385
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: O3P,HOP3,TPO
referenced by chem comp bond: P,O3P,TPO

C,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: C
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 386
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TPO
referenced by chem comp bond: CA,C,TPO
referenced by chem comp bond: C,O,TPO

O,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: O
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 387
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TPO

OXT,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: OXT
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 388
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TPO
referenced by chem comp bond: C,OXT,TPO

H,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: H
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 389
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TPO

H2,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: H2
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 390
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TPO

HA,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HA
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 391
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TPO

HB,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HB
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 392
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,TPO

HG21,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HG21
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 393
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,TPO

HG22,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HG22
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 394
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,TPO

HG23,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HG23
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 395
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,TPO

HOP2,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HOP2
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 396
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O2P,HOP2,TPO

HOP3,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HOP3
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 397
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: O3P,HOP3,TPO

HXT,TPO
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
chem comp atom.atom id: HXT
chem comp atom.comp id: TPO
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 398
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TPO

N,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: N
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 399
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: N,H,TRP

CA,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 400
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TRP
referenced by chem comp bond: N,CA,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: CA,CB,TRP

C,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: C
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 401
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TRP
referenced by chem comp bond: CA,C,TRP
referenced by chem comp bond: C,O,TRP

O,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: O
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 402
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TRP

CB,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CB
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 403
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TRP
referenced by chem comp bond: CA,CB,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CB,HB2,TRP

CG,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CG
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 404
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CB,CG,TRP
referenced by chem comp bond: CG,CD1,TRP

CD1,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 405
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TRP
referenced by chem comp bond: CG,CD1,TRP
referenced by chem comp bond: CD1,NE1,TRP

CD2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CD2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 406
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CG,CD2,TRP
referenced by chem comp bond: CD2,CE2,TRP

NE1,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: NE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 407
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: NE1,HE1,TRP
referenced by chem comp bond: CD1,NE1,TRP
referenced by chem comp bond: NE1,CE2,TRP

CE2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CE2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 408
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: NE1,CE2,TRP
referenced by chem comp bond: CD2,CE2,TRP

CE3,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 409
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE3,HE3,TRP
referenced by chem comp bond: CD2,CE3,TRP
referenced by chem comp bond: CE3,CZ3,TRP

CZ2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 410
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ2,HZ2,TRP
referenced by chem comp bond: CE2,CZ2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

CZ3,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 411
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ3,HZ3,TRP
referenced by chem comp bond: CE3,CZ3,TRP
referenced by chem comp bond: CZ3,CH2,TRP

CH2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: CH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 412
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CH2,HH2,TRP
referenced by chem comp bond: CZ3,CH2,TRP
referenced by chem comp bond: CZ2,CH2,TRP

OXT,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: OXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 413
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TRP
referenced by chem comp bond: C,OXT,TRP

H,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: H
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 414
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TRP

H2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: H2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 415
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TRP

HA,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HA
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 416
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TRP

HB2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HB2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 417
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TRP

HB3,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HB3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 418
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TRP

HD1,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HD1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 419
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TRP

HE1,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HE1
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 420
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: NE1,HE1,TRP

HE3,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HE3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 421
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE3,HE3,TRP

HZ2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HZ2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 422
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ2,HZ2,TRP

HZ3,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HZ3
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 423
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CZ3,HZ3,TRP

HH2,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HH2
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 424
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CH2,HH2,TRP

HXT,TRP
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
chem comp atom.atom id: HXT
chem comp atom.comp id: TRP
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 425
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TRP

N,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: N
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 426
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: N,H,TYR

CA,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 427
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,TYR
referenced by chem comp bond: N,CA,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: CA,CB,TYR

C,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: C
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 428
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,TYR
referenced by chem comp bond: CA,C,TYR
referenced by chem comp bond: C,O,TYR

O,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: O
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 429
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,TYR

CB,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CB
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 430
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB3,TYR
referenced by chem comp bond: CA,CB,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CB,HB2,TYR

CG,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CG
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 431
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CB,CG,TYR
referenced by chem comp bond: CG,CD1,TYR

CD1,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 432
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD1,HD1,TYR
referenced by chem comp bond: CG,CD1,TYR
referenced by chem comp bond: CD1,CE1,TYR

CD2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 433
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CD2,HD2,TYR
referenced by chem comp bond: CG,CD2,TYR
referenced by chem comp bond: CD2,CE2,TYR

CE1,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 434
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE1,HE1,TYR
referenced by chem comp bond: CD1,CE1,TYR
referenced by chem comp bond: CE1,CZ,TYR

CE2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 435
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CE2,HE2,TYR
referenced by chem comp bond: CD2,CE2,TYR
referenced by chem comp bond: CE2,CZ,TYR

CZ,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: CZ
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: Y
chem comp atom.pdbx ordinal: 436
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CZ,OH,TYR
referenced by chem comp bond: CE2,CZ,TYR
referenced by chem comp bond: CE1,CZ,TYR

OH,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: OH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 437
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OH,HH,TYR
referenced by chem comp bond: CZ,OH,TYR

OXT,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: OXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 438
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,TYR
referenced by chem comp bond: C,OXT,TYR

H,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: H
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 439
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,TYR

H2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: H2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 440
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,TYR

HA,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HA
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 441
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,TYR

HB2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HB2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 442
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB2,TYR

HB3,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HB3
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 443
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB3,TYR

HD1,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HD1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 444
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD1,HD1,TYR

HD2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HD2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 445
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CD2,HD2,TYR

HE1,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HE1
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 446
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE1,HE1,TYR

HE2,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HE2
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 447
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CE2,HE2,TYR

HH,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HH
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 448
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OH,HH,TYR

HXT,TYR
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
chem comp atom.atom id: HXT
chem comp atom.comp id: TYR
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 449
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,TYR

N,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: N
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 450
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: N
referenced by chem comp bond: N,H2,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: N,H,VAL

CA,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: CA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 451
chem comp atom.pdbx stereo config: S
chem comp atom.type symbol: C
referenced by chem comp bond: CA,HA,VAL
referenced by chem comp bond: N,CA,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: CA,CB,VAL

C,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: C
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 452
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: C,OXT,VAL
referenced by chem comp bond: CA,C,VAL
referenced by chem comp bond: C,O,VAL

O,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: O
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 453
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: C,O,VAL

CB,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: CB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 454
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CB,HB,VAL
referenced by chem comp bond: CA,CB,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CB,CG2,VAL

CG1,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: CG1
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 455
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG1,HG13,VAL
referenced by chem comp bond: CB,CG1,VAL
referenced by chem comp bond: CG1,HG11,VAL
referenced by chem comp bond: CG1,HG12,VAL

CG2,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: CG2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 456
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: C
referenced by chem comp bond: CG2,HG23,VAL
referenced by chem comp bond: CB,CG2,VAL
referenced by chem comp bond: CG2,HG21,VAL
referenced by chem comp bond: CG2,HG22,VAL

OXT,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: OXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 457
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: O
referenced by chem comp bond: OXT,HXT,VAL
referenced by chem comp bond: C,OXT,VAL

H,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: H
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 458
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H,VAL

H2,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: H2
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 459
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: N,H2,VAL

HA,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HA
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 460
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CA,HA,VAL

HB,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HB
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 461
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CB,HB,VAL

HG11,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG11
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 462
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG11,VAL

HG12,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG12
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 463
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG12,VAL

HG13,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG13
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 464
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG1,HG13,VAL

HG21,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG21
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 465
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG21,VAL

HG22,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG22
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 466
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG22,VAL

HG23,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HG23
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 467
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: CG2,HG23,VAL

HXT,VAL
type: chem comp atom
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
chem comp atom.atom id: HXT
chem comp atom.comp id: VAL
chem comp atom.pdbx aromatic flag: N
chem comp atom.pdbx ordinal: 468
chem comp atom.pdbx stereo config: N
chem comp atom.type symbol: H
referenced by chem comp bond: OXT,HXT,VAL

N,CA,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ALA
reference to chem comp atom: CA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 1
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ALA
reference to chem comp atom: H,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 2
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ALA
reference to chem comp atom: H2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 3
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ALA
reference to chem comp atom: C,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 4
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ALA
reference to chem comp atom: CB,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 5
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ALA
reference to chem comp atom: HA,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 6
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ALA
reference to chem comp atom: O,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 7
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ALA
reference to chem comp atom: OXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 8
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB1,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB1,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB1
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 9
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB2,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 10
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ALA
reference to chem comp atom: HB3,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 11
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ALA
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,ALA
reference to chem comp atom: HXT,ALA
reference to chem comp: ALA
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ALA
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 12
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ARG
reference to chem comp atom: CA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 13
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ARG
reference to chem comp atom: H,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 14
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ARG
reference to chem comp atom: H2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 15
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ARG
reference to chem comp atom: C,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 16
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ARG
reference to chem comp atom: CB,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 17
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ARG
reference to chem comp atom: HA,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 18
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ARG
reference to chem comp atom: O,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 19
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ARG
reference to chem comp atom: OXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 20
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ARG
reference to chem comp atom: CG,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 21
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 22
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ARG
reference to chem comp atom: HB3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 23
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ARG
reference to chem comp atom: CD,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 24
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 25
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ARG
reference to chem comp atom: HG3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 26
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,NE,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,ARG
reference to chem comp atom: NE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 27
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 28
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,ARG
reference to chem comp atom: HD3,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 29
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,CZ,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE,ARG
reference to chem comp atom: CZ,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: CZ
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 30
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE,HE,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE,ARG
reference to chem comp atom: HE,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NE
chem comp bond.atom id 2: HE
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 31
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH1,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH1,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH1
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 32
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,NH2,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ,ARG
reference to chem comp atom: NH2,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: NH2
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 33
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

NH1,HH11,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH11,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH11
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 34
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH1,HH12,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NH1,ARG
reference to chem comp atom: HH12,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH1
chem comp bond.atom id 2: HH12
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 35
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH21,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH21,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH21
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 36
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NH2,HH22,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NH2,ARG
reference to chem comp atom: HH22,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: NH2
chem comp bond.atom id 2: HH22
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 37
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ARG
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,ARG
reference to chem comp atom: HXT,ARG
reference to chem comp: ARG
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ARG
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 38
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASN
reference to chem comp atom: CA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 39
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASN
reference to chem comp atom: H,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 40
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASN
reference to chem comp atom: H2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 41
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASN
reference to chem comp atom: C,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 42
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASN
reference to chem comp atom: CB,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 43
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASN
reference to chem comp atom: HA,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 44
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ASN
reference to chem comp atom: O,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 45
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ASN
reference to chem comp atom: OXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 46
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASN
reference to chem comp atom: CG,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 47
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 48
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASN
reference to chem comp atom: HB3,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 49
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ASN
reference to chem comp atom: OD1,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 50
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,ND2,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ASN
reference to chem comp atom: ND2,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND2
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 51
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD21,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD21,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 52
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

ND2,HD22,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: ND2,ASN
reference to chem comp atom: HD22,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: ND2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 53
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,ASN
reference to chem comp atom: HXT,ASN
reference to chem comp: ASN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 54
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASP
reference to chem comp atom: CA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 55
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASP
reference to chem comp atom: H,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 56
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ASP
reference to chem comp atom: H2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 57
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASP
reference to chem comp atom: C,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 58
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASP
reference to chem comp atom: CB,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 59
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ASP
reference to chem comp atom: HA,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 60
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ASP
reference to chem comp atom: O,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 61
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ASP
reference to chem comp atom: OXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 62
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASP
reference to chem comp atom: CG,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 63
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 64
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ASP
reference to chem comp atom: HB3,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 65
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,OD1,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD1,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD1
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 66
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,OD2,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,ASP
reference to chem comp atom: OD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: OD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 67
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OD2,HD2,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OD2,ASP
reference to chem comp atom: HD2,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 68
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ASP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,ASP
reference to chem comp atom: HXT,ASP
reference to chem comp: ASP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ASP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 69
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,CYS
reference to chem comp atom: CA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 70
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,CYS
reference to chem comp atom: H,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 71
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,CYS
reference to chem comp atom: H2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 72
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,CYS
reference to chem comp atom: C,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 73
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,CYS
reference to chem comp atom: CB,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 74
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,CYS
reference to chem comp atom: HA,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 75
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,CYS
reference to chem comp atom: O,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 76
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,CYS
reference to chem comp atom: OXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 77
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,SG,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,CYS
reference to chem comp atom: SG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: SG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 78
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB2,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 79
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,CYS
reference to chem comp atom: HB3,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 80
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SG,HG,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: SG,CYS
reference to chem comp atom: HG,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: SG
chem comp bond.atom id 2: HG
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 81
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,CYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,CYS
reference to chem comp atom: HXT,CYS
reference to chem comp: CYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: CYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 82
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

S1,C1,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: S1,DTT
reference to chem comp atom: C1,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: S1
chem comp bond.atom id 2: C1
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 83
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

S1,HS1,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: S1,DTT
reference to chem comp atom: HS1,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: S1
chem comp bond.atom id 2: HS1
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 84
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,C2,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C1,DTT
reference to chem comp atom: C2,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: C2
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 85
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H11,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C1,DTT
reference to chem comp atom: H11,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H11
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 86
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C1,H12,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C1,DTT
reference to chem comp atom: H12,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C1
chem comp bond.atom id 2: H12
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 87
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,O2,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C2,DTT
reference to chem comp atom: O2,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: O2
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 88
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,C3,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C2,DTT
reference to chem comp atom: C3,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: C3
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 89
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,H2,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C2,DTT
reference to chem comp atom: H2,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: H2
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 90
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O2,HO2,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O2,DTT
reference to chem comp atom: HO2,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: O2
chem comp bond.atom id 2: HO2
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 91
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,O3,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C3,DTT
reference to chem comp atom: O3,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: O3
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 92
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,C4,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C3,DTT
reference to chem comp atom: C4,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: C4
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 93
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C3,H3,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C3,DTT
reference to chem comp atom: H3,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C3
chem comp bond.atom id 2: H3
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 94
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O3,HO3,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O3,DTT
reference to chem comp atom: HO3,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: O3
chem comp bond.atom id 2: HO3
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 95
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C4,S4,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C4,DTT
reference to chem comp atom: S4,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: S4
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 96
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C4,H41,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C4,DTT
reference to chem comp atom: H41,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: H41
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 97
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C4,H42,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C4,DTT
reference to chem comp atom: H42,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: H42
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 98
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

S4,HS2,DTT
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: S4,DTT
reference to chem comp atom: HS2,DTT
reference to chem comp: DTT
chem comp bond.atom id 1: S4
chem comp bond.atom id 2: HS2
chem comp bond.comp id: DTT
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 99
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLN
reference to chem comp atom: CA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 100
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLN
reference to chem comp atom: H,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 101
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLN
reference to chem comp atom: H2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 102
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLN
reference to chem comp atom: C,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 103
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLN
reference to chem comp atom: CB,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 104
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLN
reference to chem comp atom: HA,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 105
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLN
reference to chem comp atom: O,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 106
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLN
reference to chem comp atom: OXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 107
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLN
reference to chem comp atom: CG,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 108
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 109
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLN
reference to chem comp atom: HB3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 110
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLN
reference to chem comp atom: CD,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 111
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 112
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLN
reference to chem comp atom: HG3,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 113
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,GLN
reference to chem comp atom: OE1,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 114
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,NE2,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,GLN
reference to chem comp atom: NE2,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: NE2
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 115
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE21,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE21,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE21
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 116
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE22,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE2,GLN
reference to chem comp atom: HE22,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE22
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 117
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLN
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,GLN
reference to chem comp atom: HXT,GLN
reference to chem comp: GLN
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLN
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 118
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLU
reference to chem comp atom: CA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 119
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLU
reference to chem comp atom: H,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 120
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLU
reference to chem comp atom: H2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 121
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLU
reference to chem comp atom: C,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 122
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLU
reference to chem comp atom: CB,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 123
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLU
reference to chem comp atom: HA,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 124
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLU
reference to chem comp atom: O,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 125
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLU
reference to chem comp atom: OXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 126
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLU
reference to chem comp atom: CG,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 127
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 128
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,GLU
reference to chem comp atom: HB3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 129
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLU
reference to chem comp atom: CD,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 130
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 131
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,GLU
reference to chem comp atom: HG3,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 132
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,OE1,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE1,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE1
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 133
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD,OE2,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,GLU
reference to chem comp atom: OE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: OE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 134
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OE2,HE2,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OE2,GLU
reference to chem comp atom: HE2,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 135
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,GLU
reference to chem comp atom: HXT,GLU
reference to chem comp: GLU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 136
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLY
reference to chem comp atom: CA,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 137
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLY
reference to chem comp atom: H,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 138
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,GLY
reference to chem comp atom: H2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 139
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLY
reference to chem comp atom: C,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 140
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA2,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA2,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA2
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 141
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA3,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,GLY
reference to chem comp atom: HA3,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA3
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 142
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLY
reference to chem comp atom: O,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 143
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,GLY
reference to chem comp atom: OXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 144
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,GLY
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,GLY
reference to chem comp atom: HXT,GLY
reference to chem comp: GLY
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: GLY
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 145
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,HIS
reference to chem comp atom: CA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 146
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,HIS
reference to chem comp atom: H,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 147
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,HIS
reference to chem comp atom: H2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 148
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,HIS
reference to chem comp atom: C,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 149
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,HIS
reference to chem comp atom: CB,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 150
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,HIS
reference to chem comp atom: HA,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 151
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,HIS
reference to chem comp atom: O,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 152
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,HIS
reference to chem comp atom: OXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 153
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,HIS
reference to chem comp atom: CG,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 154
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 155
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,HIS
reference to chem comp atom: HB3,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 156
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,ND1,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,HIS
reference to chem comp atom: ND1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: ND1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 157
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,HIS
reference to chem comp atom: CD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 158
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,CE1,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: ND1,HIS
reference to chem comp atom: CE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 159
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

ND1,HD1,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: ND1,HIS
reference to chem comp atom: HD1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: ND1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 160
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,NE2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 161
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,HIS
reference to chem comp atom: HD2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 162
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,NE2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,HIS
reference to chem comp atom: NE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: NE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 163
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,HE1,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,HIS
reference to chem comp atom: HE1,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 164
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE2,HE2,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE2,HIS
reference to chem comp atom: HE2,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: NE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 165
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,HIS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,HIS
reference to chem comp atom: HXT,HIS
reference to chem comp: HIS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: HIS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 166
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H1,HOH
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O,HOH
reference to chem comp atom: H1,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H1
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 167
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O,H2,HOH
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O,HOH
reference to chem comp atom: H2,HOH
reference to chem comp: HOH
chem comp bond.atom id 1: O
chem comp bond.atom id 2: H2
chem comp bond.comp id: HOH
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 168
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ILE
reference to chem comp atom: CA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 169
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ILE
reference to chem comp atom: H,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 170
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,ILE
reference to chem comp atom: H2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 171
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ILE
reference to chem comp atom: C,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 172
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ILE
reference to chem comp atom: CB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 173
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,ILE
reference to chem comp atom: HA,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 174
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ILE
reference to chem comp atom: O,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 175
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,ILE
reference to chem comp atom: OXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 176
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 177
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ILE
reference to chem comp atom: CG2,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 178
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,ILE
reference to chem comp atom: HB,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 179
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,CD1,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,ILE
reference to chem comp atom: CD1,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: CD1
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 180
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 181
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,ILE
reference to chem comp atom: HG13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 182
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG21,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 183
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG22,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 184
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,ILE
reference to chem comp atom: HG23,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 185
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD11,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 186
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD12,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 187
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,ILE
reference to chem comp atom: HD13,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 188
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,ILE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,ILE
reference to chem comp atom: HXT,ILE
reference to chem comp: ILE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: ILE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 189
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

FAT,CAS,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: FAT,JYM
reference to chem comp atom: CAS,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: FAT
chem comp bond.atom id 2: CAS
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 190
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAS,FAU,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAS,JYM
reference to chem comp atom: FAU,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAS
chem comp bond.atom id 2: FAU
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 191
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAS,FAV,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAS,JYM
reference to chem comp atom: FAV,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAS
chem comp bond.atom id 2: FAV
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 192
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAS,C8,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAS,JYM
reference to chem comp atom: C8,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAS
chem comp bond.atom id 2: C8
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 193
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C8,N9,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C8,JYM
reference to chem comp atom: N9,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C8
chem comp bond.atom id 2: N9
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 194
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C8,N7,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C8,JYM
reference to chem comp atom: N7,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C8
chem comp bond.atom id 2: N7
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 195
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N9,C4,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N9,JYM
reference to chem comp atom: C4,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N9
chem comp bond.atom id 2: C4
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 196
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N7,C5,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N7,JYM
reference to chem comp atom: C5,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N7
chem comp bond.atom id 2: C5
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 197
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C5,C4,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C5,JYM
reference to chem comp atom: C4,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: C4
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 198
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C5,C6,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C5,JYM
reference to chem comp atom: C6,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C5
chem comp bond.atom id 2: C6
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 199
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C4,N3,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C4,JYM
reference to chem comp atom: N3,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C4
chem comp bond.atom id 2: N3
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 200
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N3,C2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N3,JYM
reference to chem comp atom: C2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N3
chem comp bond.atom id 2: C2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 201
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,N2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C2,JYM
reference to chem comp atom: N2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: N2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 202
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C2,N1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C2,JYM
reference to chem comp atom: N1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C2
chem comp bond.atom id 2: N1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 203
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

N1,C6,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N1,JYM
reference to chem comp atom: C6,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N1
chem comp bond.atom id 2: C6
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 204
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C6,O6,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C6,JYM
reference to chem comp atom: O6,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: C6
chem comp bond.atom id 2: O6
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 205
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O6,CAL,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O6,JYM
reference to chem comp atom: CAL,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: O6
chem comp bond.atom id 2: CAL
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 206
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAL,CAM,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAL,JYM
reference to chem comp atom: CAM,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAL
chem comp bond.atom id 2: CAM
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 207
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAM,CAN,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAM,JYM
reference to chem comp atom: CAN,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAM
chem comp bond.atom id 2: CAN
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 208
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAM,CAR,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAM,JYM
reference to chem comp atom: CAR,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAM
chem comp bond.atom id 2: CAR
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 209
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAN,CAO,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAN,JYM
reference to chem comp atom: CAO,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAN
chem comp bond.atom id 2: CAO
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 210
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAO,CAP,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAO,JYM
reference to chem comp atom: CAP,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAO
chem comp bond.atom id 2: CAP
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 211
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAP,CAQ,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAP,JYM
reference to chem comp atom: CAQ,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAP
chem comp bond.atom id 2: CAQ
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 212
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAQ,CAR,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAQ,JYM
reference to chem comp atom: CAR,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAQ
chem comp bond.atom id 2: CAR
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 213
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N9,H9,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N9,JYM
reference to chem comp atom: H9,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N9
chem comp bond.atom id 2: H9
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 214
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N2,H21N,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N2,JYM
reference to chem comp atom: H21N,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N2
chem comp bond.atom id 2: H21N
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 215
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N2,H22N,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N2,JYM
reference to chem comp atom: H22N,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: N2
chem comp bond.atom id 2: H22N
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 216
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAL,HAL1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAL,JYM
reference to chem comp atom: HAL1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAL
chem comp bond.atom id 2: HAL1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 217
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAL,HAL2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAL,JYM
reference to chem comp atom: HAL2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAL
chem comp bond.atom id 2: HAL2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 218
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAM,HAM,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAM,JYM
reference to chem comp atom: HAM,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAM
chem comp bond.atom id 2: HAM
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 219
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAN,HAN1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAN,JYM
reference to chem comp atom: HAN1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAN
chem comp bond.atom id 2: HAN1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 220
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAN,HAN2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAN,JYM
reference to chem comp atom: HAN2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAN
chem comp bond.atom id 2: HAN2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 221
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAR,HAR1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAR,JYM
reference to chem comp atom: HAR1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAR
chem comp bond.atom id 2: HAR1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 222
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAR,HAR2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAR,JYM
reference to chem comp atom: HAR2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAR
chem comp bond.atom id 2: HAR2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 223
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAO,HAO1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAO,JYM
reference to chem comp atom: HAO1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAO
chem comp bond.atom id 2: HAO1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 224
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAO,HAO2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAO,JYM
reference to chem comp atom: HAO2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAO
chem comp bond.atom id 2: HAO2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 225
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAP,HAP1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAP,JYM
reference to chem comp atom: HAP1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAP
chem comp bond.atom id 2: HAP1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 226
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAP,HAP2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAP,JYM
reference to chem comp atom: HAP2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAP
chem comp bond.atom id 2: HAP2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 227
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAQ,HAQ1,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAQ,JYM
reference to chem comp atom: HAQ1,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAQ
chem comp bond.atom id 2: HAQ1
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 228
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CAQ,HAQ2,JYM
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CAQ,JYM
reference to chem comp atom: HAQ2,JYM
reference to chem comp: JYM
chem comp bond.atom id 1: CAQ
chem comp bond.atom id 2: HAQ2
chem comp bond.comp id: JYM
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 229
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LEU
reference to chem comp atom: CA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 230
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LEU
reference to chem comp atom: H,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 231
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LEU
reference to chem comp atom: H2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 232
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LEU
reference to chem comp atom: C,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 233
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LEU
reference to chem comp atom: CB,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 234
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LEU
reference to chem comp atom: HA,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 235
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,LEU
reference to chem comp atom: O,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 236
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,LEU
reference to chem comp atom: OXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 237
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LEU
reference to chem comp atom: CG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 238
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 239
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LEU
reference to chem comp atom: HB3,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 240
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD1,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 241
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD2,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LEU
reference to chem comp atom: CD2,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 242
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LEU
reference to chem comp atom: HG,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 243
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD11,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD11,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD11
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 244
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD12,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD12,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD12
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 245
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD13,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,LEU
reference to chem comp atom: HD13,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD13
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 246
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD21,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD21,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD21
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 247
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD22,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD22,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD22
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 248
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,HD23,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,LEU
reference to chem comp atom: HD23,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD23
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 249
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LEU
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,LEU
reference to chem comp atom: HXT,LEU
reference to chem comp: LEU
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LEU
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 250
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LYS
reference to chem comp atom: CA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 251
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LYS
reference to chem comp atom: H,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 252
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,LYS
reference to chem comp atom: H2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 253
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LYS
reference to chem comp atom: C,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 254
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LYS
reference to chem comp atom: CB,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 255
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,LYS
reference to chem comp atom: HA,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 256
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,LYS
reference to chem comp atom: O,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 257
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,LYS
reference to chem comp atom: OXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 258
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LYS
reference to chem comp atom: CG,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 259
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 260
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,LYS
reference to chem comp atom: HB3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 261
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LYS
reference to chem comp atom: CD,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 262
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 263
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,LYS
reference to chem comp atom: HG3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 264
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,CE,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,LYS
reference to chem comp atom: CE,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: CE
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 265
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 266
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,LYS
reference to chem comp atom: HD3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 267
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,NZ,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,LYS
reference to chem comp atom: NZ,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: NZ
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 268
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 269
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,LYS
reference to chem comp atom: HE3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 270
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ1,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ1,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ1
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 271
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ2,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ2,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 272
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NZ,HZ3,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NZ,LYS
reference to chem comp atom: HZ3,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: NZ
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 273
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,LYS
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,LYS
reference to chem comp atom: HXT,LYS
reference to chem comp: LYS
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: LYS
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 274
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,MET
reference to chem comp atom: CA,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 275
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,MET
reference to chem comp atom: H,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 276
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,MET
reference to chem comp atom: H2,MET
reference to chem comp: MET
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 277
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,MET
reference to chem comp atom: C,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 278
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,MET
reference to chem comp atom: CB,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 279
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,MET
reference to chem comp atom: HA,MET
reference to chem comp: MET
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 280
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,MET
reference to chem comp atom: O,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 281
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,MET
reference to chem comp atom: OXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 282
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,MET
reference to chem comp atom: CG,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 283
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,MET
reference to chem comp atom: HB2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 284
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,MET
reference to chem comp atom: HB3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 285
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,SD,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,MET
reference to chem comp atom: SD,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: SD
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 286
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,MET
reference to chem comp atom: HG2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 287
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,MET
reference to chem comp atom: HG3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 288
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

SD,CE,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: SD,MET
reference to chem comp atom: CE,MET
reference to chem comp: MET
chem comp bond.atom id 1: SD
chem comp bond.atom id 2: CE
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 289
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE1,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,MET
reference to chem comp atom: HE1,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE1
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 290
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE2,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,MET
reference to chem comp atom: HE2,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE2
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 291
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE,HE3,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE,MET
reference to chem comp atom: HE3,MET
reference to chem comp: MET
chem comp bond.atom id 1: CE
chem comp bond.atom id 2: HE3
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 292
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,MET
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,MET
reference to chem comp atom: HXT,MET
reference to chem comp: MET
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: MET
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 293
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PHE
reference to chem comp atom: CA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 294
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PHE
reference to chem comp atom: H,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 295
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PHE
reference to chem comp atom: H2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 296
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PHE
reference to chem comp atom: C,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 297
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PHE
reference to chem comp atom: CB,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 298
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PHE
reference to chem comp atom: HA,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 299
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,PHE
reference to chem comp atom: O,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 300
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,PHE
reference to chem comp atom: OXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 301
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PHE
reference to chem comp atom: CG,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 302
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 303
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PHE
reference to chem comp atom: HB3,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 304
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 305
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,PHE
reference to chem comp atom: CD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 306
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,PHE
reference to chem comp atom: CE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 307
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,PHE
reference to chem comp atom: HD1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 308
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,PHE
reference to chem comp atom: CE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 309
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,PHE
reference to chem comp atom: HD2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 310
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 311
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,PHE
reference to chem comp atom: HE1,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 312
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE2,PHE
reference to chem comp atom: CZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 313
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE2,PHE
reference to chem comp atom: HE2,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 314
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,HZ,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ,PHE
reference to chem comp atom: HZ,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: HZ
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 315
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PHE
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,PHE
reference to chem comp atom: HXT,PHE
reference to chem comp: PHE
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PHE
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 316
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PRO
reference to chem comp atom: CA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 317
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CD,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 318
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,PRO
reference to chem comp atom: H,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 319
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PRO
reference to chem comp atom: C,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 320
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PRO
reference to chem comp atom: CB,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 321
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,PRO
reference to chem comp atom: HA,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 322
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,PRO
reference to chem comp atom: O,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 323
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,PRO
reference to chem comp atom: OXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 324
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PRO
reference to chem comp atom: CG,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 325
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 326
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,PRO
reference to chem comp atom: HB3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 327
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,PRO
reference to chem comp atom: CD,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 328
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG2,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 329
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,HG3,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,PRO
reference to chem comp atom: HG3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: HG3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 330
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD2,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD2,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD2
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 331
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD,HD3,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD,PRO
reference to chem comp atom: HD3,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: CD
chem comp bond.atom id 2: HD3
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 332
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,PRO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,PRO
reference to chem comp atom: HXT,PRO
reference to chem comp: PRO
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: PRO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 333
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,SER
reference to chem comp atom: CA,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 334
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,SER
reference to chem comp atom: H,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 335
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,SER
reference to chem comp atom: H2,SER
reference to chem comp: SER
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 336
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,SER
reference to chem comp atom: C,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 337
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,SER
reference to chem comp atom: CB,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 338
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,SER
reference to chem comp atom: HA,SER
reference to chem comp: SER
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 339
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,SER
reference to chem comp atom: O,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 340
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,SER
reference to chem comp atom: OXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 341
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,SER
reference to chem comp atom: OG,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 342
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,SER
reference to chem comp atom: HB2,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 343
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,SER
reference to chem comp atom: HB3,SER
reference to chem comp: SER
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 344
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG,HG,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OG,SER
reference to chem comp atom: HG,SER
reference to chem comp: SER
chem comp bond.atom id 1: OG
chem comp bond.atom id 2: HG
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 345
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,SER
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,SER
reference to chem comp atom: HXT,SER
reference to chem comp: SER
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: SER
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 346
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,THR
reference to chem comp atom: CA,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 347
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,THR
reference to chem comp atom: H,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 348
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,THR
reference to chem comp atom: H2,THR
reference to chem comp: THR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 349
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,THR
reference to chem comp atom: C,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 350
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,THR
reference to chem comp atom: CB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 351
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,THR
reference to chem comp atom: HA,THR
reference to chem comp: THR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 352
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,THR
reference to chem comp atom: O,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 353
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,THR
reference to chem comp atom: OXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 354
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG1,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,THR
reference to chem comp atom: OG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 355
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,THR
reference to chem comp atom: CG2,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 356
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,THR
reference to chem comp atom: HB,THR
reference to chem comp: THR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 357
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG1,HG1,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OG1,THR
reference to chem comp atom: HG1,THR
reference to chem comp: THR
chem comp bond.atom id 1: OG1
chem comp bond.atom id 2: HG1
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 358
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG21,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 359
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG22,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 360
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,THR
reference to chem comp atom: HG23,THR
reference to chem comp: THR
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 361
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,THR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,THR
reference to chem comp atom: HXT,THR
reference to chem comp: THR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: THR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 362
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TPO
reference to chem comp atom: CA,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 363
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TPO
reference to chem comp atom: H,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 364
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TPO
reference to chem comp atom: H2,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 365
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TPO
reference to chem comp atom: CB,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 366
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TPO
reference to chem comp atom: C,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 367
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TPO
reference to chem comp atom: HA,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 368
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TPO
reference to chem comp atom: CG2,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 369
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,OG1,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TPO
reference to chem comp atom: OG1,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: OG1
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 370
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TPO
reference to chem comp atom: HB,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 371
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,TPO
reference to chem comp atom: HG21,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 372
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,TPO
reference to chem comp atom: HG22,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 373
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,TPO
reference to chem comp atom: HG23,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 374
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OG1,P,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OG1,TPO
reference to chem comp atom: P,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: OG1
chem comp bond.atom id 2: P
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 375
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

P,O1P,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: P,TPO
reference to chem comp atom: O1P,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: P
chem comp bond.atom id 2: O1P
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 376
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

P,O2P,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: P,TPO
reference to chem comp atom: O2P,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: P
chem comp bond.atom id 2: O2P
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 377
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

P,O3P,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: P,TPO
reference to chem comp atom: O3P,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: P
chem comp bond.atom id 2: O3P
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 378
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O2P,HOP2,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O2P,TPO
reference to chem comp atom: HOP2,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: O2P
chem comp bond.atom id 2: HOP2
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 379
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

O3P,HOP3,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: O3P,TPO
reference to chem comp atom: HOP3,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: O3P
chem comp bond.atom id 2: HOP3
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 380
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TPO
reference to chem comp atom: O,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 381
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TPO
reference to chem comp atom: OXT,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 382
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TPO
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,TPO
reference to chem comp atom: HXT,TPO
reference to chem comp: TPO
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TPO
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 383
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TRP
reference to chem comp atom: CA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 384
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TRP
reference to chem comp atom: H,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 385
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TRP
reference to chem comp atom: H2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 386
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TRP
reference to chem comp atom: C,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 387
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TRP
reference to chem comp atom: CB,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 388
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TRP
reference to chem comp atom: HA,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 389
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TRP
reference to chem comp atom: O,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 390
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TRP
reference to chem comp atom: OXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 391
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TRP
reference to chem comp atom: CG,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 392
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 393
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TRP
reference to chem comp atom: HB3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 394
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 395
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,TRP
reference to chem comp atom: CD2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 396
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,NE1,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,TRP
reference to chem comp atom: NE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: NE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 397
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,TRP
reference to chem comp atom: HD1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 398
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 399
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,CE3,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,TRP
reference to chem comp atom: CE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 400
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,CE2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE1,TRP
reference to chem comp atom: CE2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 401
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

NE1,HE1,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: NE1,TRP
reference to chem comp atom: HE1,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: NE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 402
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE2,TRP
reference to chem comp atom: CZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 403
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE3,CZ3,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE3,TRP
reference to chem comp atom: CZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: CZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 404
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE3,HE3,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE3,TRP
reference to chem comp atom: HE3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CE3
chem comp bond.atom id 2: HE3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 405
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ2,CH2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 406
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CZ2,HZ2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ2,TRP
reference to chem comp atom: HZ2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ2
chem comp bond.atom id 2: HZ2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 407
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,CH2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: CH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: CH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 408
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ3,HZ3,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ3,TRP
reference to chem comp atom: HZ3,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CZ3
chem comp bond.atom id 2: HZ3
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 409
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CH2,HH2,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CH2,TRP
reference to chem comp atom: HH2,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: CH2
chem comp bond.atom id 2: HH2
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 410
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TRP
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,TRP
reference to chem comp atom: HXT,TRP
reference to chem comp: TRP
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TRP
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 411
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TYR
reference to chem comp atom: CA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 412
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TYR
reference to chem comp atom: H,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 413
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,TYR
reference to chem comp atom: H2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 414
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TYR
reference to chem comp atom: C,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 415
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TYR
reference to chem comp atom: CB,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 416
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,TYR
reference to chem comp atom: HA,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 417
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TYR
reference to chem comp atom: O,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 418
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,TYR
reference to chem comp atom: OXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 419
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TYR
reference to chem comp atom: CG,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 420
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 421
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB3,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,TYR
reference to chem comp atom: HB3,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB3
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 422
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG,CD1,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 423
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CG,CD2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG,TYR
reference to chem comp atom: CD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CG
chem comp bond.atom id 2: CD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 424
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,CE1,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,TYR
reference to chem comp atom: CE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: CE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 425
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD1,HD1,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD1,TYR
reference to chem comp atom: HD1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD1
chem comp bond.atom id 2: HD1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 426
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CD2,CE2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,TYR
reference to chem comp atom: CE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: CE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 427
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CD2,HD2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CD2,TYR
reference to chem comp atom: HD2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CD2
chem comp bond.atom id 2: HD2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 428
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE1,CZ,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 429
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

CE1,HE1,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE1,TYR
reference to chem comp atom: HE1,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE1
chem comp bond.atom id 2: HE1
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 430
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,CZ,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE2,TYR
reference to chem comp atom: CZ,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: CZ
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: Y
chem comp bond.pdbx ordinal: 431
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CE2,HE2,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CE2,TYR
reference to chem comp atom: HE2,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CE2
chem comp bond.atom id 2: HE2
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 432
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CZ,OH,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CZ,TYR
reference to chem comp atom: OH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: CZ
chem comp bond.atom id 2: OH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 433
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OH,HH,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OH,TYR
reference to chem comp atom: HH,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OH
chem comp bond.atom id 2: HH
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 434
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,TYR
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,TYR
reference to chem comp atom: HXT,TYR
reference to chem comp: TYR
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: TYR
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 435
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,CA,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,VAL
reference to chem comp atom: CA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: CA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 436
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,VAL
reference to chem comp atom: H,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 437
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

N,H2,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: N,VAL
reference to chem comp atom: H2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: N
chem comp bond.atom id 2: H2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 438
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,C,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,VAL
reference to chem comp atom: C,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: C
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 439
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,CB,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,VAL
reference to chem comp atom: CB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: CB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 440
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CA,HA,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CA,VAL
reference to chem comp atom: HA,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CA
chem comp bond.atom id 2: HA
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 441
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

C,O,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,VAL
reference to chem comp atom: O,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: O
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 442
chem comp bond.pdbx stereo config: N
chem comp bond.value order: doub

C,OXT,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: C,VAL
reference to chem comp atom: OXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: C
chem comp bond.atom id 2: OXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 443
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG1,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG1,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG1
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 444
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,CG2,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,VAL
reference to chem comp atom: CG2,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: CG2
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 445
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CB,HB,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CB,VAL
reference to chem comp atom: HB,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CB
chem comp bond.atom id 2: HB
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 446
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG11,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG11,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG11
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 447
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG12,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG12,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG12
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 448
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG1,HG13,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG1,VAL
reference to chem comp atom: HG13,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG1
chem comp bond.atom id 2: HG13
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 449
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG21,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG21,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG21
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 450
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG22,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG22,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG22
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 451
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

CG2,HG23,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: CG2,VAL
reference to chem comp atom: HG23,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: CG2
chem comp bond.atom id 2: HG23
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 452
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

OXT,HXT,VAL
type: chem comp bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp atom: OXT,VAL
reference to chem comp atom: HXT,VAL
reference to chem comp: VAL
chem comp bond.atom id 1: OXT
chem comp bond.atom id 2: HXT
chem comp bond.comp id: VAL
chem comp bond.pdbx aromatic flag: N
chem comp bond.pdbx ordinal: 453
chem comp bond.pdbx stereo config: N
chem comp bond.value order: sing

primary
type: citation
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
citation.id: primary
citation.country: US
citation.journal abbrev: J.Med.Chem.
citation.journal id ASTM: JMCMAR
citation.journal id CSD: 0151
citation.journal id ISSN: 0022-2623
citation.journal volume: 57
citation.page first: 56
citation.pdbx database id DOI: 10.1021/JM401555V
citation.pdbx database id pub med: 24304238
citation.title: 8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
citation.year: 2014
link to doi: doi:10.1021/JM401555V
link to pubmed: pubmed:24304238
references: pubmed:24304238
referenced by citation author: primary,Griffin, R.J.,16
referenced by citation author: primary,Carbain, B.,1
referenced by citation author: primary,Paterson, D.J.,2
referenced by citation author: primary,Anscombe, E.,3
referenced by citation author: primary,Campbell-Dexter, A.,4
referenced by citation author: primary,Cano, C.,5
referenced by citation author: primary,Echalier, A.,6
referenced by citation author: primary,Endicott, J.,7
referenced by citation author: primary,Golding, B.T.,8
referenced by citation author: primary,Haggerty, K.,9
referenced by citation author: primary,Hardcastle, I.R.,10
referenced by citation author: primary,Jewsbury, P.J.,11
referenced by citation author: primary,Newell, D.R.,12
referenced by citation author: primary,Noble, M.,13
referenced by citation author: primary,Roche, C.,14
referenced by citation author: primary,Wang, L.,15

primary,Carbain, B.,1
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Carbain, B.
citation author.ordinal: 1

primary,Paterson, D.J.,2
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Paterson, D.J.
citation author.ordinal: 2

primary,Anscombe, E.,3
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Anscombe, E.
citation author.ordinal: 3

primary,Campbell-Dexter, A.,4
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Campbell-Dexter, A.
citation author.ordinal: 4

primary,Cano, C.,5
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Cano, C.
citation author.ordinal: 5

primary,Echalier, A.,6
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Echalier, A.
citation author.ordinal: 6

primary,Endicott, J.,7
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Endicott, J.
citation author.ordinal: 7

primary,Golding, B.T.,8
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Golding, B.T.
citation author.ordinal: 8

primary,Haggerty, K.,9
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Haggerty, K.
citation author.ordinal: 9

primary,Hardcastle, I.R.,10
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Hardcastle, I.R.
citation author.ordinal: 10

primary,Jewsbury, P.J.,11
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Jewsbury, P.J.
citation author.ordinal: 11

primary,Newell, D.R.,12
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Newell, D.R.
citation author.ordinal: 12

primary,Noble, M.,13
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Noble, M.
citation author.ordinal: 13

primary,Roche, C.,14
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Roche, C.
citation author.ordinal: 14

primary,Wang, L.,15
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Wang, L.
citation author.ordinal: 15

primary,Griffin, R.J.,16
type: citation author
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to citation: primary
citation author.citation id: primary
citation author.name: Griffin, R.J.
citation author.ordinal: 16

4CFN,PDB
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of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
database 2.database code: 4CFN
database 2.database id: PDB
database 2.pdbx DOI: 10.2210/pdb4cfn/pdb
database 2.pdbx database accession: pdb_00004cfn

EBI-59013,PDBE
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of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
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database 2.database id: PDBE

D 1290059013,WWPDB
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database 2.database code: D_1290059013
database 2.database id: WWPDB

4CFN
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of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
database PDB matrix.entry id: 4CFN
database PDB matrix.origx11: 1
database PDB matrix.origx12: 0
database PDB matrix.origx13: 0
database PDB matrix.origx21: 0
database PDB matrix.origx22: 1
database PDB matrix.origx23: 0
database PDB matrix.origx31: 0
database PDB matrix.origx32: 0
database PDB matrix.origx33: 1
database PDB matrix.origx vector1: 0
database PDB matrix.origx vector2: 0
database PDB matrix.origx vector3: 0

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exptl crystal.id: 1
exptl crystal.density matthews: 2.87
exptl crystal.density percent sol: 57.16
exptl crystal.description: NONE
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diffrn detector.detector: CCD
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reference to diffrn: http://rdf.wwpdb.org/pdb/4CFN/diffrn/1
diffrn radiation.diffrn id: 1
diffrn radiation.pdbx diffrn protocol: SINGLE WAVELENGTH
diffrn radiation.pdbx monochromatic or laue m l: M
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diffrn radiation.wavelength id: 1

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diffrn radiation wavelength.id: 1
diffrn radiation wavelength.wavelength: 0.934
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diffrn source.diffrn id: 1
diffrn source.pdbx synchrotron beamline: ID14-2
diffrn source.pdbx synchrotron site: ESRF
diffrn source.pdbx wavelength: 0.934
diffrn source.source: SYNCHROTRON
diffrn source.type: ESRF BEAMLINE ID14-2

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of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
entity.id: 1
entity.details: PHOSPHORYLATED ON RESIDUE T160
entity.formula weight: 34354.77
entity.pdbx description: CYCLIN-DEPENDENT KINASE 2
entity.pdbx ec: 2.7.11.22, 2.7.11.23
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entity.pdbx fragment: CDK-ACTIVATING FRAGMENT, RESIDUES 175-432
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entity.id: 3
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http://rdf.wwpdb.org/pdb/4CFN/entity_name_com/2
type: entity name com
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/2
entity name com.entity id: 2
entity name com.name: CYCLIN-A

http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
type: entity poly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/1
entity poly.entity id: 1
entity poly.nstd linkage: no
entity poly.nstd monomer: yes
entity poly.pdbx seq one letter code: GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV RTY(TPO)HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
entity poly.pdbx seq one letter code can: GPGSMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKL YLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPV RTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
entity poly.pdbx strand id: A,C
entity poly.type: polypeptide(L)
referenced by entity poly seq: 1,LEU,302
referenced by entity poly seq: 1,GLY,1
referenced by entity poly seq: 1,PRO,2
referenced by entity poly seq: 1,GLY,3
referenced by entity poly seq: 1,SER,4
referenced by entity poly seq: 1,MET,5
referenced by entity poly seq: 1,GLU,6
referenced by entity poly seq: 1,ASN,7
referenced by entity poly seq: 1,PHE,8
referenced by entity poly seq: 1,GLN,9
referenced by entity poly seq: 1,LYS,10
referenced by entity poly seq: 1,VAL,11
referenced by entity poly seq: 1,GLU,12
referenced by entity poly seq: 1,LYS,13
referenced by entity poly seq: 1,ILE,14
referenced by entity poly seq: 1,GLY,15
referenced by entity poly seq: 1,GLU,16
referenced by entity poly seq: 1,GLY,17
referenced by entity poly seq: 1,THR,18
referenced by entity poly seq: 1,TYR,19
referenced by entity poly seq: 1,GLY,20
referenced by entity poly seq: 1,VAL,21
referenced by entity poly seq: 1,VAL,22
referenced by entity poly seq: 1,TYR,23
referenced by entity poly seq: 1,LYS,24
referenced by entity poly seq: 1,ALA,25
referenced by entity poly seq: 1,ARG,26
referenced by entity poly seq: 1,ASN,27
referenced by entity poly seq: 1,LYS,28
referenced by entity poly seq: 1,LEU,29
referenced by entity poly seq: 1,THR,30
referenced by entity poly seq: 1,GLY,31
referenced by entity poly seq: 1,GLU,32
referenced by entity poly seq: 1,VAL,33
referenced by entity poly seq: 1,VAL,34
referenced by entity poly seq: 1,ALA,35
referenced by entity poly seq: 1,LEU,36
referenced by entity poly seq: 1,LYS,37
referenced by entity poly seq: 1,LYS,38
referenced by entity poly seq: 1,ILE,39
referenced by entity poly seq: 1,ARG,40
referenced by entity poly seq: 1,LEU,41
referenced by entity poly seq: 1,ASP,42
referenced by entity poly seq: 1,THR,43
referenced by entity poly seq: 1,GLU,44
referenced by entity poly seq: 1,THR,45
referenced by entity poly seq: 1,GLU,46
referenced by entity poly seq: 1,GLY,47
referenced by entity poly seq: 1,VAL,48
referenced by entity poly seq: 1,PRO,49
referenced by entity poly seq: 1,SER,50
referenced by entity poly seq: 1,THR,51
referenced by entity poly seq: 1,ALA,52
referenced by entity poly seq: 1,ILE,53
referenced by entity poly seq: 1,ARG,54
referenced by entity poly seq: 1,GLU,55
referenced by entity poly seq: 1,ILE,56
referenced by entity poly seq: 1,SER,57
referenced by entity poly seq: 1,LEU,58
referenced by entity poly seq: 1,LEU,59
referenced by entity poly seq: 1,LYS,60
referenced by entity poly seq: 1,GLU,61
referenced by entity poly seq: 1,LEU,62
referenced by entity poly seq: 1,ASN,63
referenced by entity poly seq: 1,HIS,64
referenced by entity poly seq: 1,PRO,65
referenced by entity poly seq: 1,ASN,66
referenced by entity poly seq: 1,ILE,67
referenced by entity poly seq: 1,VAL,68
referenced by entity poly seq: 1,LYS,69

http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
type: entity poly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/2
entity poly.entity id: 2
entity poly.nstd linkage: no
entity poly.nstd monomer: no
entity poly.pdbx seq one letter code: VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQ LVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYK NSKYHGVSLLNPPETLNL
entity poly.pdbx seq one letter code can: VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQ LVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYK NSKYHGVSLLNPPETLNL
entity poly.pdbx strand id: B,D
entity poly.type: polypeptide(L)
referenced by entity poly seq: 2,LEU,258
referenced by entity poly seq: 2,VAL,1
referenced by entity poly seq: 2,PRO,2
referenced by entity poly seq: 2,ASP,3
referenced by entity poly seq: 2,TYR,4
referenced by entity poly seq: 2,HIS,5
referenced by entity poly seq: 2,GLU,6
referenced by entity poly seq: 2,ASP,7
referenced by entity poly seq: 2,ILE,8
referenced by entity poly seq: 2,HIS,9
referenced by entity poly seq: 2,THR,10
referenced by entity poly seq: 2,TYR,11
referenced by entity poly seq: 2,LEU,12
referenced by entity poly seq: 2,ARG,13
referenced by entity poly seq: 2,GLU,14
referenced by entity poly seq: 2,MET,15
referenced by entity poly seq: 2,GLU,16
referenced by entity poly seq: 2,VAL,17
referenced by entity poly seq: 2,LYS,18
referenced by entity poly seq: 2,CYS,19
referenced by entity poly seq: 2,LYS,20
referenced by entity poly seq: 2,PRO,21
referenced by entity poly seq: 2,LYS,22
referenced by entity poly seq: 2,VAL,23
referenced by entity poly seq: 2,GLY,24
referenced by entity poly seq: 2,TYR,25
referenced by entity poly seq: 2,MET,26
referenced by entity poly seq: 2,LYS,27
referenced by entity poly seq: 2,LYS,28
referenced by entity poly seq: 2,GLN,29
referenced by entity poly seq: 2,PRO,30
referenced by entity poly seq: 2,ASP,31
referenced by entity poly seq: 2,ILE,32
referenced by entity poly seq: 2,THR,33
referenced by entity poly seq: 2,ASN,34
referenced by entity poly seq: 2,SER,35
referenced by entity poly seq: 2,MET,36
referenced by entity poly seq: 2,ARG,37
referenced by entity poly seq: 2,ALA,38
referenced by entity poly seq: 2,ILE,39
referenced by entity poly seq: 2,LEU,40
referenced by entity poly seq: 2,VAL,41
referenced by entity poly seq: 2,ASP,42
referenced by entity poly seq: 2,TRP,43
referenced by entity poly seq: 2,LEU,44
referenced by entity poly seq: 2,VAL,45
referenced by entity poly seq: 2,GLU,46
referenced by entity poly seq: 2,VAL,47
referenced by entity poly seq: 2,GLY,48
referenced by entity poly seq: 2,GLU,49
referenced by entity poly seq: 2,GLU,50
referenced by entity poly seq: 2,TYR,51
referenced by entity poly seq: 2,LYS,52
referenced by entity poly seq: 2,LEU,53
referenced by entity poly seq: 2,GLN,54
referenced by entity poly seq: 2,ASN,55
referenced by entity poly seq: 2,GLU,56
referenced by entity poly seq: 2,THR,57
referenced by entity poly seq: 2,LEU,58
referenced by entity poly seq: 2,HIS,59
referenced by entity poly seq: 2,LEU,60
referenced by entity poly seq: 2,ALA,61
referenced by entity poly seq: 2,VAL,62
referenced by entity poly seq: 2,ASN,63
referenced by entity poly seq: 2,TYR,64
referenced by entity poly seq: 2,ILE,65
referenced by entity poly seq: 2,ASP,66
referenced by entity poly seq: 2,ARG,67
referenced by entity poly seq: 2,PHE,68
referenced by entity poly seq: 2,LEU,69

1,GLY,1
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 1
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,1
referenced by pdbx poly seq scheme: A,1,GLY,1

1,PRO,2
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 2
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,2
referenced by pdbx poly seq scheme: A,1,PRO,2

1,GLY,3
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 3
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,3
referenced by pdbx poly seq scheme: A,1,GLY,3

1,SER,4
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 4
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,4
referenced by pdbx poly seq scheme: A,1,SER,4

1,MET,5
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 5
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,MET,5
referenced by pdbx poly seq scheme: A,1,MET,5

1,GLU,6
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 6
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,6
referenced by pdbx poly seq scheme: A,1,GLU,6

1,ASN,7
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 7
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,7
referenced by pdbx poly seq scheme: A,1,ASN,7

1,PHE,8
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 8
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,8
referenced by pdbx poly seq scheme: A,1,PHE,8

1,GLN,9
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 9
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,9
referenced by pdbx poly seq scheme: A,1,GLN,9

1,LYS,10
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 10
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,10
referenced by pdbx poly seq scheme: A,1,LYS,10

1,VAL,11
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 11
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,11
referenced by pdbx poly seq scheme: A,1,VAL,11

1,GLU,12
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 12
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,12
referenced by pdbx poly seq scheme: A,1,GLU,12

1,LYS,13
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 13
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,13
referenced by pdbx poly seq scheme: A,1,LYS,13

1,ILE,14
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 14
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,14
referenced by pdbx poly seq scheme: A,1,ILE,14

1,GLY,15
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 15
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,15
referenced by pdbx poly seq scheme: A,1,GLY,15

1,GLU,16
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 16
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,16
referenced by pdbx poly seq scheme: A,1,GLU,16

1,GLY,17
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 17
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,17
referenced by pdbx poly seq scheme: A,1,GLY,17

1,THR,18
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 18
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,18
referenced by pdbx poly seq scheme: A,1,THR,18

1,TYR,19
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 19
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,19
referenced by pdbx poly seq scheme: A,1,TYR,19

1,GLY,20
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 20
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,20
referenced by pdbx poly seq scheme: A,1,GLY,20

1,VAL,21
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 21
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,21
referenced by pdbx poly seq scheme: A,1,VAL,21

1,VAL,22
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 22
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,22
referenced by pdbx poly seq scheme: A,1,VAL,22

1,TYR,23
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 23
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,23
referenced by pdbx poly seq scheme: A,1,TYR,23

1,LYS,24
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 24
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,24
referenced by pdbx poly seq scheme: A,1,LYS,24

1,ALA,25
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 25
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,25
referenced by pdbx poly seq scheme: A,1,ALA,25

1,ARG,26
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 26
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,26
referenced by pdbx poly seq scheme: A,1,ARG,26

1,ASN,27
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 27
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,27
referenced by pdbx poly seq scheme: A,1,ASN,27

1,LYS,28
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 28
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,28
referenced by pdbx poly seq scheme: A,1,LYS,28

1,LEU,29
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 29
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,29
referenced by pdbx poly seq scheme: A,1,LEU,29

1,THR,30
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 30
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,30
referenced by pdbx poly seq scheme: A,1,THR,30

1,GLY,31
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 31
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,31
referenced by pdbx poly seq scheme: A,1,GLY,31

1,GLU,32
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 32
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,32
referenced by pdbx poly seq scheme: A,1,GLU,32

1,VAL,33
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 33
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,33
referenced by pdbx poly seq scheme: A,1,VAL,33

1,VAL,34
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 34
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,34
referenced by pdbx poly seq scheme: A,1,VAL,34

1,ALA,35
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 35
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,35
referenced by pdbx poly seq scheme: A,1,ALA,35

1,LEU,36
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 36
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,36
referenced by pdbx poly seq scheme: A,1,LEU,36

1,LYS,37
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 37
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,37
referenced by pdbx poly seq scheme: A,1,LYS,37

1,LYS,38
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 38
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,38
referenced by pdbx poly seq scheme: A,1,LYS,38

1,ILE,39
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 39
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,39
referenced by pdbx poly seq scheme: A,1,ILE,39

1,ARG,40
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 40
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,40
referenced by pdbx poly seq scheme: A,1,ARG,40

1,LEU,41
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 41
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,41
referenced by pdbx poly seq scheme: A,1,LEU,41

1,ASP,42
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 42
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,42
referenced by pdbx poly seq scheme: A,1,ASP,42

1,THR,43
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 43
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,43
referenced by pdbx poly seq scheme: A,1,THR,43

1,GLU,44
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 44
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,44
referenced by pdbx poly seq scheme: A,1,GLU,44

1,THR,45
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 45
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,45
referenced by pdbx poly seq scheme: A,1,THR,45

1,GLU,46
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 46
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,46
referenced by pdbx poly seq scheme: A,1,GLU,46

1,GLY,47
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 47
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,47
referenced by pdbx poly seq scheme: A,1,GLY,47

1,VAL,48
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 48
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,48
referenced by pdbx poly seq scheme: A,1,VAL,48

1,PRO,49
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 49
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,49
referenced by pdbx poly seq scheme: A,1,PRO,49

1,SER,50
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 50
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,50
referenced by pdbx poly seq scheme: A,1,SER,50

1,THR,51
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 51
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,51
referenced by pdbx poly seq scheme: A,1,THR,51

1,ALA,52
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 52
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,52
referenced by pdbx poly seq scheme: A,1,ALA,52

1,ILE,53
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 53
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,53
referenced by pdbx poly seq scheme: A,1,ILE,53

1,ARG,54
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 54
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,54
referenced by pdbx poly seq scheme: A,1,ARG,54

1,GLU,55
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 55
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,55
referenced by pdbx poly seq scheme: A,1,GLU,55

1,ILE,56
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 56
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,56
referenced by pdbx poly seq scheme: A,1,ILE,56

1,SER,57
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 57
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,57
referenced by pdbx poly seq scheme: A,1,SER,57

1,LEU,58
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 58
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,58
referenced by pdbx poly seq scheme: A,1,LEU,58

1,LEU,59
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 59
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,59
referenced by pdbx poly seq scheme: A,1,LEU,59

1,LYS,60
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 60
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,60
referenced by pdbx poly seq scheme: A,1,LYS,60

1,GLU,61
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 61
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,61
referenced by pdbx poly seq scheme: A,1,GLU,61

1,LEU,62
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 62
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,62
referenced by pdbx poly seq scheme: A,1,LEU,62

1,ASN,63
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 63
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,63
referenced by pdbx poly seq scheme: A,1,ASN,63

1,HIS,64
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 64
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,64
referenced by pdbx poly seq scheme: A,1,HIS,64

1,PRO,65
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 65
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,65
referenced by pdbx poly seq scheme: A,1,PRO,65

1,ASN,66
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 66
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,66
referenced by pdbx poly seq scheme: A,1,ASN,66

1,ILE,67
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 67
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,67
referenced by pdbx poly seq scheme: A,1,ILE,67

1,VAL,68
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 68
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,68
referenced by pdbx poly seq scheme: A,1,VAL,68

1,LYS,69
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 69
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,69
referenced by pdbx poly seq scheme: A,1,LYS,69

1,LEU,70
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 70
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,70
referenced by pdbx poly seq scheme: A,1,LEU,70

1,LEU,71
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 71
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,71
referenced by pdbx poly seq scheme: A,1,LEU,71

1,ASP,72
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 72
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,72
referenced by pdbx poly seq scheme: A,1,ASP,72

1,VAL,73
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 73
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,73
referenced by pdbx poly seq scheme: A,1,VAL,73

1,ILE,74
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 74
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,74
referenced by pdbx poly seq scheme: A,1,ILE,74

1,HIS,75
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 75
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,75
referenced by pdbx poly seq scheme: A,1,HIS,75

1,THR,76
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 76
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,76
referenced by pdbx poly seq scheme: A,1,THR,76

1,GLU,77
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 77
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,77
referenced by pdbx poly seq scheme: A,1,GLU,77

1,ASN,78
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 78
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,78
referenced by pdbx poly seq scheme: A,1,ASN,78

1,LYS,79
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 79
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,79
referenced by pdbx poly seq scheme: A,1,LYS,79

1,LEU,80
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 80
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,80
referenced by pdbx poly seq scheme: A,1,LEU,80

1,TYR,81
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 81
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,81
referenced by pdbx poly seq scheme: A,1,TYR,81

1,LEU,82
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 82
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,82
referenced by pdbx poly seq scheme: A,1,LEU,82

1,VAL,83
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 83
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,83
referenced by pdbx poly seq scheme: A,1,VAL,83

1,PHE,84
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 84
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,84
referenced by pdbx poly seq scheme: A,1,PHE,84

1,GLU,85
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 85
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,85
referenced by pdbx poly seq scheme: A,1,GLU,85

1,PHE,86
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 86
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,86
referenced by pdbx poly seq scheme: A,1,PHE,86

1,LEU,87
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 87
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,87
referenced by pdbx poly seq scheme: A,1,LEU,87

1,HIS,88
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 88
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,88
referenced by pdbx poly seq scheme: A,1,HIS,88

1,GLN,89
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 89
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,89
referenced by pdbx poly seq scheme: A,1,GLN,89

1,ASP,90
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 90
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,90
referenced by pdbx poly seq scheme: A,1,ASP,90

1,LEU,91
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 91
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,91
referenced by pdbx poly seq scheme: A,1,LEU,91

1,LYS,92
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 92
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,92
referenced by pdbx poly seq scheme: A,1,LYS,92

1,LYS,93
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 93
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,93
referenced by pdbx poly seq scheme: A,1,LYS,93

1,PHE,94
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 94
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,94
referenced by pdbx poly seq scheme: A,1,PHE,94

1,MET,95
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 95
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,MET,95
referenced by pdbx poly seq scheme: A,1,MET,95

1,ASP,96
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 96
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,96
referenced by pdbx poly seq scheme: A,1,ASP,96

1,ALA,97
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 97
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,97
referenced by pdbx poly seq scheme: A,1,ALA,97

1,SER,98
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 98
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,98
referenced by pdbx poly seq scheme: A,1,SER,98

1,ALA,99
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 99
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,99
referenced by pdbx poly seq scheme: A,1,ALA,99

1,LEU,100
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 100
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,100
referenced by pdbx poly seq scheme: A,1,LEU,100

1,THR,101
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 101
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,101
referenced by pdbx poly seq scheme: A,1,THR,101

1,GLY,102
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 102
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,102
referenced by pdbx poly seq scheme: A,1,GLY,102

1,ILE,103
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 103
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,103
referenced by pdbx poly seq scheme: A,1,ILE,103

1,PRO,104
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 104
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,104
referenced by pdbx poly seq scheme: A,1,PRO,104

1,LEU,105
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 105
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,105
referenced by pdbx poly seq scheme: A,1,LEU,105

1,PRO,106
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 106
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,106
referenced by pdbx poly seq scheme: A,1,PRO,106

1,LEU,107
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 107
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,107
referenced by pdbx poly seq scheme: A,1,LEU,107

1,ILE,108
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 108
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,108
referenced by pdbx poly seq scheme: A,1,ILE,108

1,LYS,109
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 109
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,109
referenced by pdbx poly seq scheme: A,1,LYS,109

1,SER,110
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 110
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,110
referenced by pdbx poly seq scheme: A,1,SER,110

1,TYR,111
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 111
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,111
referenced by pdbx poly seq scheme: A,1,TYR,111

1,LEU,112
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 112
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,112
referenced by pdbx poly seq scheme: A,1,LEU,112

1,PHE,113
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 113
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,113
referenced by pdbx poly seq scheme: A,1,PHE,113

1,GLN,114
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 114
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,114
referenced by pdbx poly seq scheme: A,1,GLN,114

1,LEU,115
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 115
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,115
referenced by pdbx poly seq scheme: A,1,LEU,115

1,LEU,116
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 116
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,116
referenced by pdbx poly seq scheme: A,1,LEU,116

1,GLN,117
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 117
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,117
referenced by pdbx poly seq scheme: A,1,GLN,117

1,GLY,118
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 118
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,118
referenced by pdbx poly seq scheme: A,1,GLY,118

1,LEU,119
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 119
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,119
referenced by pdbx poly seq scheme: A,1,LEU,119

1,ALA,120
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 120
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,120
referenced by pdbx poly seq scheme: A,1,ALA,120

1,PHE,121
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 121
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,121
referenced by pdbx poly seq scheme: A,1,PHE,121

1,CYS,122
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 122
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,CYS,122
referenced by pdbx poly seq scheme: A,1,CYS,122

1,HIS,123
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 123
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,123
referenced by pdbx poly seq scheme: A,1,HIS,123

1,SER,124
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 124
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,124
referenced by pdbx poly seq scheme: A,1,SER,124

1,HIS,125
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 125
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,125
referenced by pdbx poly seq scheme: A,1,HIS,125

1,ARG,126
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 126
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,126
referenced by pdbx poly seq scheme: A,1,ARG,126

1,VAL,127
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 127
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,127
referenced by pdbx poly seq scheme: A,1,VAL,127

1,LEU,128
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 128
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,128
referenced by pdbx poly seq scheme: A,1,LEU,128

1,HIS,129
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 129
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,129
referenced by pdbx poly seq scheme: A,1,HIS,129

1,ARG,130
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 130
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,130
referenced by pdbx poly seq scheme: A,1,ARG,130

1,ASP,131
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 131
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,131
referenced by pdbx poly seq scheme: A,1,ASP,131

1,LEU,132
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 132
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,132
referenced by pdbx poly seq scheme: A,1,LEU,132

1,LYS,133
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 133
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,133
referenced by pdbx poly seq scheme: A,1,LYS,133

1,PRO,134
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 134
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,134
referenced by pdbx poly seq scheme: A,1,PRO,134

1,GLN,135
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 135
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,135
referenced by pdbx poly seq scheme: A,1,GLN,135

1,ASN,136
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 136
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,136
referenced by pdbx poly seq scheme: A,1,ASN,136

1,LEU,137
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 137
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,137
referenced by pdbx poly seq scheme: A,1,LEU,137

1,LEU,138
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 138
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,138
referenced by pdbx poly seq scheme: A,1,LEU,138

1,ILE,139
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 139
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,139
referenced by pdbx poly seq scheme: A,1,ILE,139

1,ASN,140
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 140
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,140
referenced by pdbx poly seq scheme: A,1,ASN,140

1,THR,141
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 141
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,141
referenced by pdbx poly seq scheme: A,1,THR,141

1,GLU,142
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 142
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,142
referenced by pdbx poly seq scheme: A,1,GLU,142

1,GLY,143
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 143
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,143
referenced by pdbx poly seq scheme: A,1,GLY,143

1,ALA,144
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 144
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,144
referenced by pdbx poly seq scheme: A,1,ALA,144

1,ILE,145
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 145
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,145
referenced by pdbx poly seq scheme: A,1,ILE,145

1,LYS,146
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 146
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,146
referenced by pdbx poly seq scheme: A,1,LYS,146

1,LEU,147
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 147
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,147
referenced by pdbx poly seq scheme: A,1,LEU,147

1,ALA,148
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 148
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,148
referenced by pdbx poly seq scheme: A,1,ALA,148

1,ASP,149
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 149
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,149
referenced by pdbx poly seq scheme: A,1,ASP,149

1,PHE,150
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 150
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,150
referenced by pdbx poly seq scheme: A,1,PHE,150

1,GLY,151
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 151
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,151
referenced by pdbx poly seq scheme: A,1,GLY,151

1,LEU,152
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 152
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,152
referenced by pdbx poly seq scheme: A,1,LEU,152

1,ALA,153
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 153
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,153
referenced by pdbx poly seq scheme: A,1,ALA,153

1,ARG,154
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 154
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,154
referenced by pdbx poly seq scheme: A,1,ARG,154

1,ALA,155
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 155
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,155
referenced by pdbx poly seq scheme: A,1,ALA,155

1,PHE,156
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 156
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,156
referenced by pdbx poly seq scheme: A,1,PHE,156

1,GLY,157
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 157
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,157
referenced by pdbx poly seq scheme: A,1,GLY,157

1,VAL,158
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 158
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,158
referenced by pdbx poly seq scheme: A,1,VAL,158

1,PRO,159
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 159
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,159
referenced by pdbx poly seq scheme: A,1,PRO,159

1,VAL,160
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 160
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,160
referenced by pdbx poly seq scheme: A,1,VAL,160

1,ARG,161
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 161
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,161
referenced by pdbx poly seq scheme: A,1,ARG,161

1,THR,162
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 162
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,162
referenced by pdbx poly seq scheme: A,1,THR,162

1,TYR,163
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 163
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,163
referenced by pdbx poly seq scheme: A,1,TYR,163

1,TPO,164
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TPO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TPO
entity poly seq.num: 164
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TPO,164
referenced by pdbx poly seq scheme: A,1,TPO,164

1,HIS,165
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 165
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,165
referenced by pdbx poly seq scheme: A,1,HIS,165

1,GLU,166
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 166
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,166
referenced by pdbx poly seq scheme: A,1,GLU,166

1,VAL,167
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 167
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,167
referenced by pdbx poly seq scheme: A,1,VAL,167

1,VAL,168
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 168
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,168
referenced by pdbx poly seq scheme: A,1,VAL,168

1,THR,169
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 169
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,169
referenced by pdbx poly seq scheme: A,1,THR,169

1,LEU,170
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 170
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,170
referenced by pdbx poly seq scheme: A,1,LEU,170

1,TRP,171
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 171
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TRP,171
referenced by pdbx poly seq scheme: A,1,TRP,171

1,TYR,172
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 172
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,172
referenced by pdbx poly seq scheme: A,1,TYR,172

1,ARG,173
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 173
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,173
referenced by pdbx poly seq scheme: A,1,ARG,173

1,ALA,174
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 174
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,174
referenced by pdbx poly seq scheme: A,1,ALA,174

1,PRO,175
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 175
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,175
referenced by pdbx poly seq scheme: A,1,PRO,175

1,GLU,176
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 176
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,176
referenced by pdbx poly seq scheme: A,1,GLU,176

1,ILE,177
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 177
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,177
referenced by pdbx poly seq scheme: A,1,ILE,177

1,LEU,178
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 178
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,178
referenced by pdbx poly seq scheme: A,1,LEU,178

1,LEU,179
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 179
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,179
referenced by pdbx poly seq scheme: A,1,LEU,179

1,GLY,180
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 180
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,180
referenced by pdbx poly seq scheme: A,1,GLY,180

1,CYS,181
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 181
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,CYS,181
referenced by pdbx poly seq scheme: A,1,CYS,181

1,LYS,182
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 182
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,182
referenced by pdbx poly seq scheme: A,1,LYS,182

1,TYR,183
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 183
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,183
referenced by pdbx poly seq scheme: A,1,TYR,183

1,TYR,184
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 184
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,184
referenced by pdbx poly seq scheme: A,1,TYR,184

1,SER,185
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 185
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,185
referenced by pdbx poly seq scheme: A,1,SER,185

1,THR,186
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 186
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,186
referenced by pdbx poly seq scheme: A,1,THR,186

1,ALA,187
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 187
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,187
referenced by pdbx poly seq scheme: A,1,ALA,187

1,VAL,188
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 188
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,188
referenced by pdbx poly seq scheme: A,1,VAL,188

1,ASP,189
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 189
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,189
referenced by pdbx poly seq scheme: A,1,ASP,189

1,ILE,190
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 190
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,190
referenced by pdbx poly seq scheme: A,1,ILE,190

1,TRP,191
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 191
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TRP,191
referenced by pdbx poly seq scheme: A,1,TRP,191

1,SER,192
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 192
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,192
referenced by pdbx poly seq scheme: A,1,SER,192

1,LEU,193
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 193
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,193
referenced by pdbx poly seq scheme: A,1,LEU,193

1,GLY,194
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 194
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,194
referenced by pdbx poly seq scheme: A,1,GLY,194

1,CYS,195
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 195
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,CYS,195
referenced by pdbx poly seq scheme: A,1,CYS,195

1,ILE,196
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 196
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,196
referenced by pdbx poly seq scheme: A,1,ILE,196

1,PHE,197
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 197
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,197
referenced by pdbx poly seq scheme: A,1,PHE,197

1,ALA,198
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 198
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,198
referenced by pdbx poly seq scheme: A,1,ALA,198

1,GLU,199
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 199
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,199
referenced by pdbx poly seq scheme: A,1,GLU,199

1,MET,200
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 200
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,MET,200
referenced by pdbx poly seq scheme: A,1,MET,200

1,VAL,201
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 201
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,201
referenced by pdbx poly seq scheme: A,1,VAL,201

1,THR,202
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 202
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,202
referenced by pdbx poly seq scheme: A,1,THR,202

1,ARG,203
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 203
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,203
referenced by pdbx poly seq scheme: A,1,ARG,203

1,ARG,204
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 204
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,204
referenced by pdbx poly seq scheme: A,1,ARG,204

1,ALA,205
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 205
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,205
referenced by pdbx poly seq scheme: A,1,ALA,205

1,LEU,206
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 206
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,206
referenced by pdbx poly seq scheme: A,1,LEU,206

1,PHE,207
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 207
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,207
referenced by pdbx poly seq scheme: A,1,PHE,207

1,PRO,208
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 208
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,208
referenced by pdbx poly seq scheme: A,1,PRO,208

1,GLY,209
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 209
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,209
referenced by pdbx poly seq scheme: A,1,GLY,209

1,ASP,210
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 210
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,210
referenced by pdbx poly seq scheme: A,1,ASP,210

1,SER,211
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 211
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,211
referenced by pdbx poly seq scheme: A,1,SER,211

1,GLU,212
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 212
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,212
referenced by pdbx poly seq scheme: A,1,GLU,212

1,ILE,213
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 213
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,213
referenced by pdbx poly seq scheme: A,1,ILE,213

1,ASP,214
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 214
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,214
referenced by pdbx poly seq scheme: A,1,ASP,214

1,GLN,215
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 215
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,215
referenced by pdbx poly seq scheme: A,1,GLN,215

1,LEU,216
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 216
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,216
referenced by pdbx poly seq scheme: A,1,LEU,216

1,PHE,217
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 217
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,217
referenced by pdbx poly seq scheme: A,1,PHE,217

1,ARG,218
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 218
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,218
referenced by pdbx poly seq scheme: A,1,ARG,218

1,ILE,219
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 219
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,219
referenced by pdbx poly seq scheme: A,1,ILE,219

1,PHE,220
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 220
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,220
referenced by pdbx poly seq scheme: A,1,PHE,220

1,ARG,221
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 221
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,221
referenced by pdbx poly seq scheme: A,1,ARG,221

1,THR,222
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 222
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,222
referenced by pdbx poly seq scheme: A,1,THR,222

1,LEU,223
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 223
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,223
referenced by pdbx poly seq scheme: A,1,LEU,223

1,GLY,224
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 224
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,224
referenced by pdbx poly seq scheme: A,1,GLY,224

1,THR,225
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 225
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,225
referenced by pdbx poly seq scheme: A,1,THR,225

1,PRO,226
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 226
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,226
referenced by pdbx poly seq scheme: A,1,PRO,226

1,ASP,227
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 227
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,227
referenced by pdbx poly seq scheme: A,1,ASP,227

1,GLU,228
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 228
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,228
referenced by pdbx poly seq scheme: A,1,GLU,228

1,VAL,229
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 229
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,229
referenced by pdbx poly seq scheme: A,1,VAL,229

1,VAL,230
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 230
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,230
referenced by pdbx poly seq scheme: A,1,VAL,230

1,TRP,231
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 231
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TRP,231
referenced by pdbx poly seq scheme: A,1,TRP,231

1,PRO,232
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 232
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,232
referenced by pdbx poly seq scheme: A,1,PRO,232

1,GLY,233
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 233
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,233
referenced by pdbx poly seq scheme: A,1,GLY,233

1,VAL,234
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 234
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,234
referenced by pdbx poly seq scheme: A,1,VAL,234

1,THR,235
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 235
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,235
referenced by pdbx poly seq scheme: A,1,THR,235

1,SER,236
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 236
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,236
referenced by pdbx poly seq scheme: A,1,SER,236

1,MET,237
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 237
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,MET,237
referenced by pdbx poly seq scheme: A,1,MET,237

1,PRO,238
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 238
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,238
referenced by pdbx poly seq scheme: A,1,PRO,238

1,ASP,239
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 239
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,239
referenced by pdbx poly seq scheme: A,1,ASP,239

1,TYR,240
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 240
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,240
referenced by pdbx poly seq scheme: A,1,TYR,240

1,LYS,241
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 241
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,241
referenced by pdbx poly seq scheme: A,1,LYS,241

1,PRO,242
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 242
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,242
referenced by pdbx poly seq scheme: A,1,PRO,242

1,SER,243
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 243
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,243
referenced by pdbx poly seq scheme: A,1,SER,243

1,PHE,244
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 244
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,244
referenced by pdbx poly seq scheme: A,1,PHE,244

1,PRO,245
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 245
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,245
referenced by pdbx poly seq scheme: A,1,PRO,245

1,LYS,246
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 246
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,246
referenced by pdbx poly seq scheme: A,1,LYS,246

1,TRP,247
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 247
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TRP,247
referenced by pdbx poly seq scheme: A,1,TRP,247

1,ALA,248
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 248
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,248
referenced by pdbx poly seq scheme: A,1,ALA,248

1,ARG,249
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 249
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,249
referenced by pdbx poly seq scheme: A,1,ARG,249

1,GLN,250
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 250
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,250
referenced by pdbx poly seq scheme: A,1,GLN,250

1,ASP,251
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 251
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,251
referenced by pdbx poly seq scheme: A,1,ASP,251

1,PHE,252
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 252
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,252
referenced by pdbx poly seq scheme: A,1,PHE,252

1,SER,253
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 253
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,253
referenced by pdbx poly seq scheme: A,1,SER,253

1,LYS,254
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 254
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,254
referenced by pdbx poly seq scheme: A,1,LYS,254

1,VAL,255
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 255
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,255
referenced by pdbx poly seq scheme: A,1,VAL,255

1,VAL,256
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 256
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,256
referenced by pdbx poly seq scheme: A,1,VAL,256

1,PRO,257
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 257
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,257
referenced by pdbx poly seq scheme: A,1,PRO,257

1,PRO,258
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 258
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,258
referenced by pdbx poly seq scheme: A,1,PRO,258

1,LEU,259
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 259
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,259
referenced by pdbx poly seq scheme: A,1,LEU,259

1,ASP,260
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 260
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,260
referenced by pdbx poly seq scheme: A,1,ASP,260

1,GLU,261
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 261
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLU,261
referenced by pdbx poly seq scheme: A,1,GLU,261

1,ASP,262
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 262
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,262
referenced by pdbx poly seq scheme: A,1,ASP,262

1,GLY,263
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 263
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLY,263
referenced by pdbx poly seq scheme: A,1,GLY,263

1,ARG,264
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 264
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,264
referenced by pdbx poly seq scheme: A,1,ARG,264

1,SER,265
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 265
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,265
referenced by pdbx poly seq scheme: A,1,SER,265

1,LEU,266
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 266
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,266
referenced by pdbx poly seq scheme: A,1,LEU,266

1,LEU,267
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 267
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,267
referenced by pdbx poly seq scheme: A,1,LEU,267

1,SER,268
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 268
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,268
referenced by pdbx poly seq scheme: A,1,SER,268

1,GLN,269
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 269
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,269
referenced by pdbx poly seq scheme: A,1,GLN,269

1,MET,270
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 270
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,MET,270
referenced by pdbx poly seq scheme: A,1,MET,270

1,LEU,271
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 271
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,271
referenced by pdbx poly seq scheme: A,1,LEU,271

1,HIS,272
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 272
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,272
referenced by pdbx poly seq scheme: A,1,HIS,272

1,TYR,273
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 273
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,TYR,273
referenced by pdbx poly seq scheme: A,1,TYR,273

1,ASP,274
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 274
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,274
referenced by pdbx poly seq scheme: A,1,ASP,274

1,PRO,275
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 275
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,275
referenced by pdbx poly seq scheme: A,1,PRO,275

1,ASN,276
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 276
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASN,276
referenced by pdbx poly seq scheme: A,1,ASN,276

1,LYS,277
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 277
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,277
referenced by pdbx poly seq scheme: A,1,LYS,277

1,ARG,278
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 278
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,278
referenced by pdbx poly seq scheme: A,1,ARG,278

1,ILE,279
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 279
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ILE,279
referenced by pdbx poly seq scheme: A,1,ILE,279

1,SER,280
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 280
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,SER,280
referenced by pdbx poly seq scheme: A,1,SER,280

1,ALA,281
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 281
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,281
referenced by pdbx poly seq scheme: A,1,ALA,281

1,LYS,282
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 282
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,282
referenced by pdbx poly seq scheme: A,1,LYS,282

1,ALA,283
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 283
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,283
referenced by pdbx poly seq scheme: A,1,ALA,283

1,ALA,284
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 284
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,284
referenced by pdbx poly seq scheme: A,1,ALA,284

1,LEU,285
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 285
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,285
referenced by pdbx poly seq scheme: A,1,LEU,285

1,ALA,286
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 286
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ALA,286
referenced by pdbx poly seq scheme: A,1,ALA,286

1,HIS,287
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 287
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,287
referenced by pdbx poly seq scheme: A,1,HIS,287

1,PRO,288
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 288
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,288
referenced by pdbx poly seq scheme: A,1,PRO,288

1,PHE,289
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 289
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,289
referenced by pdbx poly seq scheme: A,1,PHE,289

1,PHE,290
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 290
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PHE,290
referenced by pdbx poly seq scheme: A,1,PHE,290

1,GLN,291
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 291
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,GLN,291
referenced by pdbx poly seq scheme: A,1,GLN,291

1,ASP,292
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 292
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ASP,292
referenced by pdbx poly seq scheme: A,1,ASP,292

1,VAL,293
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 293
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,293
referenced by pdbx poly seq scheme: A,1,VAL,293

1,THR,294
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 294
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,THR,294
referenced by pdbx poly seq scheme: A,1,THR,294

1,LYS,295
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 295
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LYS,295
referenced by pdbx poly seq scheme: A,1,LYS,295

1,PRO,296
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 296
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,296
referenced by pdbx poly seq scheme: A,1,PRO,296

1,VAL,297
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 297
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,VAL,297
referenced by pdbx poly seq scheme: A,1,VAL,297

1,PRO,298
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 298
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,PRO,298
referenced by pdbx poly seq scheme: A,1,PRO,298

1,HIS,299
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 299
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,HIS,299
referenced by pdbx poly seq scheme: A,1,HIS,299

1,LEU,300
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 300
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,300
referenced by pdbx poly seq scheme: A,1,LEU,300

1,ARG,301
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 301
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,ARG,301
referenced by pdbx poly seq scheme: A,1,ARG,301

1,LEU,302
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/1
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 302
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: C,1,LEU,302
referenced by pdbx poly seq scheme: A,1,LEU,302

2,VAL,1
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 1
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,1
referenced by pdbx poly seq scheme: B,2,VAL,1

2,PRO,2
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 2
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,2
referenced by pdbx poly seq scheme: B,2,PRO,2

2,ASP,3
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 3
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,3
referenced by pdbx poly seq scheme: B,2,ASP,3

2,TYR,4
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 4
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,4
referenced by pdbx poly seq scheme: B,2,TYR,4

2,HIS,5
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 5
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,5
referenced by pdbx poly seq scheme: B,2,HIS,5

2,GLU,6
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 6
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,6
referenced by pdbx poly seq scheme: B,2,GLU,6

2,ASP,7
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 7
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,7
referenced by pdbx poly seq scheme: B,2,ASP,7

2,ILE,8
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 8
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,8
referenced by pdbx poly seq scheme: B,2,ILE,8

2,HIS,9
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 9
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,9
referenced by pdbx poly seq scheme: B,2,HIS,9

2,THR,10
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 10
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,10
referenced by pdbx poly seq scheme: B,2,THR,10

2,TYR,11
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 11
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,11
referenced by pdbx poly seq scheme: B,2,TYR,11

2,LEU,12
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 12
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,12
referenced by pdbx poly seq scheme: B,2,LEU,12

2,ARG,13
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 13
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,13
referenced by pdbx poly seq scheme: B,2,ARG,13

2,GLU,14
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 14
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,14
referenced by pdbx poly seq scheme: B,2,GLU,14

2,MET,15
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 15
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,15
referenced by pdbx poly seq scheme: B,2,MET,15

2,GLU,16
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 16
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,16
referenced by pdbx poly seq scheme: B,2,GLU,16

2,VAL,17
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 17
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,17
referenced by pdbx poly seq scheme: B,2,VAL,17

2,LYS,18
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 18
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,18
referenced by pdbx poly seq scheme: B,2,LYS,18

2,CYS,19
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: CYS
entity poly seq.num: 19
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,CYS,19
referenced by pdbx poly seq scheme: B,2,CYS,19

2,LYS,20
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 20
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,20
referenced by pdbx poly seq scheme: B,2,LYS,20

2,PRO,21
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 21
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,21
referenced by pdbx poly seq scheme: B,2,PRO,21

2,LYS,22
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 22
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,22
referenced by pdbx poly seq scheme: B,2,LYS,22

2,VAL,23
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 23
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,23
referenced by pdbx poly seq scheme: B,2,VAL,23

2,GLY,24
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 24
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,24
referenced by pdbx poly seq scheme: B,2,GLY,24

2,TYR,25
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 25
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,25
referenced by pdbx poly seq scheme: B,2,TYR,25

2,MET,26
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 26
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,26
referenced by pdbx poly seq scheme: B,2,MET,26

2,LYS,27
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 27
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,27
referenced by pdbx poly seq scheme: B,2,LYS,27

2,LYS,28
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 28
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,28
referenced by pdbx poly seq scheme: B,2,LYS,28

2,GLN,29
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 29
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,29
referenced by pdbx poly seq scheme: B,2,GLN,29

2,PRO,30
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 30
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,30
referenced by pdbx poly seq scheme: B,2,PRO,30

2,ASP,31
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 31
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,31
referenced by pdbx poly seq scheme: B,2,ASP,31

2,ILE,32
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 32
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,32
referenced by pdbx poly seq scheme: B,2,ILE,32

2,THR,33
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 33
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,33
referenced by pdbx poly seq scheme: B,2,THR,33

2,ASN,34
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 34
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,34
referenced by pdbx poly seq scheme: B,2,ASN,34

2,SER,35
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 35
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,35
referenced by pdbx poly seq scheme: B,2,SER,35

2,MET,36
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 36
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,36
referenced by pdbx poly seq scheme: B,2,MET,36

2,ARG,37
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 37
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,37
referenced by pdbx poly seq scheme: B,2,ARG,37

2,ALA,38
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 38
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,38
referenced by pdbx poly seq scheme: B,2,ALA,38

2,ILE,39
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 39
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,39
referenced by pdbx poly seq scheme: B,2,ILE,39

2,LEU,40
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 40
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,40
referenced by pdbx poly seq scheme: B,2,LEU,40

2,VAL,41
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 41
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,41
referenced by pdbx poly seq scheme: B,2,VAL,41

2,ASP,42
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 42
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,42
referenced by pdbx poly seq scheme: B,2,ASP,42

2,TRP,43
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TRP
entity poly seq.num: 43
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TRP,43
referenced by pdbx poly seq scheme: B,2,TRP,43

2,LEU,44
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 44
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,44
referenced by pdbx poly seq scheme: B,2,LEU,44

2,VAL,45
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 45
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,45
referenced by pdbx poly seq scheme: B,2,VAL,45

2,GLU,46
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 46
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,46
referenced by pdbx poly seq scheme: B,2,GLU,46

2,VAL,47
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 47
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,47
referenced by pdbx poly seq scheme: B,2,VAL,47

2,GLY,48
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 48
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,48
referenced by pdbx poly seq scheme: B,2,GLY,48

2,GLU,49
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 49
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,49
referenced by pdbx poly seq scheme: B,2,GLU,49

2,GLU,50
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 50
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,50
referenced by pdbx poly seq scheme: B,2,GLU,50

2,TYR,51
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 51
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,51
referenced by pdbx poly seq scheme: B,2,TYR,51

2,LYS,52
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 52
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,52
referenced by pdbx poly seq scheme: B,2,LYS,52

2,LEU,53
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 53
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,53
referenced by pdbx poly seq scheme: B,2,LEU,53

2,GLN,54
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 54
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,54
referenced by pdbx poly seq scheme: B,2,GLN,54

2,ASN,55
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 55
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,55
referenced by pdbx poly seq scheme: B,2,ASN,55

2,GLU,56
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 56
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,56
referenced by pdbx poly seq scheme: B,2,GLU,56

2,THR,57
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 57
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,57
referenced by pdbx poly seq scheme: B,2,THR,57

2,LEU,58
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 58
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,58
referenced by pdbx poly seq scheme: B,2,LEU,58

2,HIS,59
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 59
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,59
referenced by pdbx poly seq scheme: B,2,HIS,59

2,LEU,60
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 60
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,60
referenced by pdbx poly seq scheme: B,2,LEU,60

2,ALA,61
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 61
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,61
referenced by pdbx poly seq scheme: B,2,ALA,61

2,VAL,62
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 62
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,62
referenced by pdbx poly seq scheme: B,2,VAL,62

2,ASN,63
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 63
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,63
referenced by pdbx poly seq scheme: B,2,ASN,63

2,TYR,64
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 64
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,64
referenced by pdbx poly seq scheme: B,2,TYR,64

2,ILE,65
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 65
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,65
referenced by pdbx poly seq scheme: B,2,ILE,65

2,ASP,66
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 66
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,66
referenced by pdbx poly seq scheme: B,2,ASP,66

2,ARG,67
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 67
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,67
referenced by pdbx poly seq scheme: B,2,ARG,67

2,PHE,68
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 68
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,68
referenced by pdbx poly seq scheme: B,2,PHE,68

2,LEU,69
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 69
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,69
referenced by pdbx poly seq scheme: B,2,LEU,69

2,SER,70
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 70
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,70
referenced by pdbx poly seq scheme: B,2,SER,70

2,SER,71
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 71
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,71
referenced by pdbx poly seq scheme: B,2,SER,71

2,MET,72
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 72
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,72
referenced by pdbx poly seq scheme: B,2,MET,72

2,SER,73
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 73
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,73
referenced by pdbx poly seq scheme: B,2,SER,73

2,VAL,74
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 74
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,74
referenced by pdbx poly seq scheme: B,2,VAL,74

2,LEU,75
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 75
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,75
referenced by pdbx poly seq scheme: B,2,LEU,75

2,ARG,76
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 76
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,76
referenced by pdbx poly seq scheme: B,2,ARG,76

2,GLY,77
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 77
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,77
referenced by pdbx poly seq scheme: B,2,GLY,77

2,LYS,78
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 78
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,78
referenced by pdbx poly seq scheme: B,2,LYS,78

2,LEU,79
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 79
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,79
referenced by pdbx poly seq scheme: B,2,LEU,79

2,GLN,80
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 80
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,80
referenced by pdbx poly seq scheme: B,2,GLN,80

2,LEU,81
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 81
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,81
referenced by pdbx poly seq scheme: B,2,LEU,81

2,VAL,82
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 82
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,82
referenced by pdbx poly seq scheme: B,2,VAL,82

2,GLY,83
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 83
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,83
referenced by pdbx poly seq scheme: B,2,GLY,83

2,THR,84
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 84
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,84
referenced by pdbx poly seq scheme: B,2,THR,84

2,ALA,85
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 85
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,85
referenced by pdbx poly seq scheme: B,2,ALA,85

2,ALA,86
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 86
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,86
referenced by pdbx poly seq scheme: B,2,ALA,86

2,MET,87
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 87
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,87
referenced by pdbx poly seq scheme: B,2,MET,87

2,LEU,88
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 88
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,88
referenced by pdbx poly seq scheme: B,2,LEU,88

2,LEU,89
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 89
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,89
referenced by pdbx poly seq scheme: B,2,LEU,89

2,ALA,90
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 90
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,90
referenced by pdbx poly seq scheme: B,2,ALA,90

2,SER,91
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 91
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,91
referenced by pdbx poly seq scheme: B,2,SER,91

2,LYS,92
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 92
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,92
referenced by pdbx poly seq scheme: B,2,LYS,92

2,PHE,93
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 93
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,93
referenced by pdbx poly seq scheme: B,2,PHE,93

2,GLU,94
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 94
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,94
referenced by pdbx poly seq scheme: B,2,GLU,94

2,GLU,95
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 95
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,95
referenced by pdbx poly seq scheme: B,2,GLU,95

2,ILE,96
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 96
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,96
referenced by pdbx poly seq scheme: B,2,ILE,96

2,TYR,97
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 97
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,97
referenced by pdbx poly seq scheme: B,2,TYR,97

2,PRO,98
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 98
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,98
referenced by pdbx poly seq scheme: B,2,PRO,98

2,PRO,99
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 99
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,99
referenced by pdbx poly seq scheme: B,2,PRO,99

2,GLU,100
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 100
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,100
referenced by pdbx poly seq scheme: B,2,GLU,100

2,VAL,101
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 101
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,101
referenced by pdbx poly seq scheme: B,2,VAL,101

2,ALA,102
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 102
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,102
referenced by pdbx poly seq scheme: B,2,ALA,102

2,GLU,103
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 103
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,103
referenced by pdbx poly seq scheme: B,2,GLU,103

2,PHE,104
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 104
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,104
referenced by pdbx poly seq scheme: B,2,PHE,104

2,VAL,105
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 105
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,105
referenced by pdbx poly seq scheme: B,2,VAL,105

2,TYR,106
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 106
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,106
referenced by pdbx poly seq scheme: B,2,TYR,106

2,ILE,107
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 107
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,107
referenced by pdbx poly seq scheme: B,2,ILE,107

2,THR,108
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 108
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,108
referenced by pdbx poly seq scheme: B,2,THR,108

2,ASP,109
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 109
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,109
referenced by pdbx poly seq scheme: B,2,ASP,109

2,ASP,110
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 110
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,110
referenced by pdbx poly seq scheme: B,2,ASP,110

2,THR,111
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 111
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,111
referenced by pdbx poly seq scheme: B,2,THR,111

2,TYR,112
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 112
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,112
referenced by pdbx poly seq scheme: B,2,TYR,112

2,THR,113
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 113
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,113
referenced by pdbx poly seq scheme: B,2,THR,113

2,LYS,114
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 114
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,114
referenced by pdbx poly seq scheme: B,2,LYS,114

2,LYS,115
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 115
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,115
referenced by pdbx poly seq scheme: B,2,LYS,115

2,GLN,116
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 116
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,116
referenced by pdbx poly seq scheme: B,2,GLN,116

2,VAL,117
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 117
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,117
referenced by pdbx poly seq scheme: B,2,VAL,117

2,LEU,118
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 118
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,118
referenced by pdbx poly seq scheme: B,2,LEU,118

2,ARG,119
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 119
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,119
referenced by pdbx poly seq scheme: B,2,ARG,119

2,MET,120
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 120
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,120
referenced by pdbx poly seq scheme: B,2,MET,120

2,GLU,121
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 121
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,121
referenced by pdbx poly seq scheme: B,2,GLU,121

2,HIS,122
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 122
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,122
referenced by pdbx poly seq scheme: B,2,HIS,122

2,LEU,123
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 123
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,123
referenced by pdbx poly seq scheme: B,2,LEU,123

2,VAL,124
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 124
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,124
referenced by pdbx poly seq scheme: B,2,VAL,124

2,LEU,125
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 125
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,125
referenced by pdbx poly seq scheme: B,2,LEU,125

2,LYS,126
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 126
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,126
referenced by pdbx poly seq scheme: B,2,LYS,126

2,VAL,127
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 127
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,127
referenced by pdbx poly seq scheme: B,2,VAL,127

2,LEU,128
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 128
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,128
referenced by pdbx poly seq scheme: B,2,LEU,128

2,THR,129
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 129
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,129
referenced by pdbx poly seq scheme: B,2,THR,129

2,PHE,130
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 130
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,130
referenced by pdbx poly seq scheme: B,2,PHE,130

2,ASP,131
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 131
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,131
referenced by pdbx poly seq scheme: B,2,ASP,131

2,LEU,132
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 132
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,132
referenced by pdbx poly seq scheme: B,2,LEU,132

2,ALA,133
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 133
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,133
referenced by pdbx poly seq scheme: B,2,ALA,133

2,ALA,134
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 134
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,134
referenced by pdbx poly seq scheme: B,2,ALA,134

2,PRO,135
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 135
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,135
referenced by pdbx poly seq scheme: B,2,PRO,135

2,THR,136
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 136
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,136
referenced by pdbx poly seq scheme: B,2,THR,136

2,VAL,137
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 137
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,137
referenced by pdbx poly seq scheme: B,2,VAL,137

2,ASN,138
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 138
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,138
referenced by pdbx poly seq scheme: B,2,ASN,138

2,GLN,139
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 139
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,139
referenced by pdbx poly seq scheme: B,2,GLN,139

2,PHE,140
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 140
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,140
referenced by pdbx poly seq scheme: B,2,PHE,140

2,LEU,141
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 141
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,141
referenced by pdbx poly seq scheme: B,2,LEU,141

2,THR,142
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 142
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,142
referenced by pdbx poly seq scheme: B,2,THR,142

2,GLN,143
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 143
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,143
referenced by pdbx poly seq scheme: B,2,GLN,143

2,TYR,144
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 144
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,144
referenced by pdbx poly seq scheme: B,2,TYR,144

2,PHE,145
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 145
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,145
referenced by pdbx poly seq scheme: B,2,PHE,145

2,LEU,146
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 146
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,146
referenced by pdbx poly seq scheme: B,2,LEU,146

2,HIS,147
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 147
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,147
referenced by pdbx poly seq scheme: B,2,HIS,147

2,GLN,148
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 148
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,148
referenced by pdbx poly seq scheme: B,2,GLN,148

2,GLN,149
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 149
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,149
referenced by pdbx poly seq scheme: B,2,GLN,149

2,PRO,150
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 150
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,150
referenced by pdbx poly seq scheme: B,2,PRO,150

2,ALA,151
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 151
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,151
referenced by pdbx poly seq scheme: B,2,ALA,151

2,ASN,152
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 152
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,152
referenced by pdbx poly seq scheme: B,2,ASN,152

2,CYS,153
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: CYS
entity poly seq.num: 153
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,CYS,153
referenced by pdbx poly seq scheme: B,2,CYS,153

2,LYS,154
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 154
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,154
referenced by pdbx poly seq scheme: B,2,LYS,154

2,VAL,155
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 155
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,155
referenced by pdbx poly seq scheme: B,2,VAL,155

2,GLU,156
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 156
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,156
referenced by pdbx poly seq scheme: B,2,GLU,156

2,SER,157
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 157
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,157
referenced by pdbx poly seq scheme: B,2,SER,157

2,LEU,158
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 158
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,158
referenced by pdbx poly seq scheme: B,2,LEU,158

2,ALA,159
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 159
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,159
referenced by pdbx poly seq scheme: B,2,ALA,159

2,MET,160
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 160
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,160
referenced by pdbx poly seq scheme: B,2,MET,160

2,PHE,161
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 161
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,161
referenced by pdbx poly seq scheme: B,2,PHE,161

2,LEU,162
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 162
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,162
referenced by pdbx poly seq scheme: B,2,LEU,162

2,GLY,163
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 163
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,163
referenced by pdbx poly seq scheme: B,2,GLY,163

2,GLU,164
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 164
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,164
referenced by pdbx poly seq scheme: B,2,GLU,164

2,LEU,165
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 165
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,165
referenced by pdbx poly seq scheme: B,2,LEU,165

2,SER,166
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 166
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,166
referenced by pdbx poly seq scheme: B,2,SER,166

2,LEU,167
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 167
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,167
referenced by pdbx poly seq scheme: B,2,LEU,167

2,ILE,168
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 168
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,168
referenced by pdbx poly seq scheme: B,2,ILE,168

2,ASP,169
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 169
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,169
referenced by pdbx poly seq scheme: B,2,ASP,169

2,ALA,170
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 170
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,170
referenced by pdbx poly seq scheme: B,2,ALA,170

2,ASP,171
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 171
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,171
referenced by pdbx poly seq scheme: B,2,ASP,171

2,PRO,172
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 172
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,172
referenced by pdbx poly seq scheme: B,2,PRO,172

2,TYR,173
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 173
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,173
referenced by pdbx poly seq scheme: B,2,TYR,173

2,LEU,174
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 174
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,174
referenced by pdbx poly seq scheme: B,2,LEU,174

2,LYS,175
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 175
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,175
referenced by pdbx poly seq scheme: B,2,LYS,175

2,TYR,176
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 176
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,176
referenced by pdbx poly seq scheme: B,2,TYR,176

2,LEU,177
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 177
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,177
referenced by pdbx poly seq scheme: B,2,LEU,177

2,PRO,178
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 178
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,178
referenced by pdbx poly seq scheme: B,2,PRO,178

2,SER,179
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 179
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,179
referenced by pdbx poly seq scheme: B,2,SER,179

2,VAL,180
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 180
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,180
referenced by pdbx poly seq scheme: B,2,VAL,180

2,ILE,181
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 181
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,181
referenced by pdbx poly seq scheme: B,2,ILE,181

2,ALA,182
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 182
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,182
referenced by pdbx poly seq scheme: B,2,ALA,182

2,GLY,183
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 183
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,183
referenced by pdbx poly seq scheme: B,2,GLY,183

2,ALA,184
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 184
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,184
referenced by pdbx poly seq scheme: B,2,ALA,184

2,ALA,185
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 185
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,185
referenced by pdbx poly seq scheme: B,2,ALA,185

2,PHE,186
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PHE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PHE
entity poly seq.num: 186
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PHE,186
referenced by pdbx poly seq scheme: B,2,PHE,186

2,HIS,187
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 187
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,187
referenced by pdbx poly seq scheme: B,2,HIS,187

2,LEU,188
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 188
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,188
referenced by pdbx poly seq scheme: B,2,LEU,188

2,ALA,189
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 189
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,189
referenced by pdbx poly seq scheme: B,2,ALA,189

2,LEU,190
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 190
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,190
referenced by pdbx poly seq scheme: B,2,LEU,190

2,TYR,191
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 191
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,191
referenced by pdbx poly seq scheme: B,2,TYR,191

2,THR,192
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 192
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,192
referenced by pdbx poly seq scheme: B,2,THR,192

2,VAL,193
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 193
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,193
referenced by pdbx poly seq scheme: B,2,VAL,193

2,THR,194
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 194
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,194
referenced by pdbx poly seq scheme: B,2,THR,194

2,GLY,195
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 195
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,195
referenced by pdbx poly seq scheme: B,2,GLY,195

2,GLN,196
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 196
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,196
referenced by pdbx poly seq scheme: B,2,GLN,196

2,SER,197
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 197
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,197
referenced by pdbx poly seq scheme: B,2,SER,197

2,TRP,198
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TRP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TRP
entity poly seq.num: 198
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TRP,198
referenced by pdbx poly seq scheme: B,2,TRP,198

2,PRO,199
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 199
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,199
referenced by pdbx poly seq scheme: B,2,PRO,199

2,GLU,200
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 200
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,200
referenced by pdbx poly seq scheme: B,2,GLU,200

2,SER,201
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 201
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,201
referenced by pdbx poly seq scheme: B,2,SER,201

2,LEU,202
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 202
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,202
referenced by pdbx poly seq scheme: B,2,LEU,202

2,ILE,203
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 203
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,203
referenced by pdbx poly seq scheme: B,2,ILE,203

2,ARG,204
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 204
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,204
referenced by pdbx poly seq scheme: B,2,ARG,204

2,LYS,205
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 205
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,205
referenced by pdbx poly seq scheme: B,2,LYS,205

2,THR,206
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 206
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,206
referenced by pdbx poly seq scheme: B,2,THR,206

2,GLY,207
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 207
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,207
referenced by pdbx poly seq scheme: B,2,GLY,207

2,TYR,208
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 208
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,208
referenced by pdbx poly seq scheme: B,2,TYR,208

2,THR,209
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 209
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,209
referenced by pdbx poly seq scheme: B,2,THR,209

2,LEU,210
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 210
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,210
referenced by pdbx poly seq scheme: B,2,LEU,210

2,GLU,211
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 211
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,211
referenced by pdbx poly seq scheme: B,2,GLU,211

2,SER,212
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 212
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,212
referenced by pdbx poly seq scheme: B,2,SER,212

2,LEU,213
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 213
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,213
referenced by pdbx poly seq scheme: B,2,LEU,213

2,LYS,214
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 214
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,214
referenced by pdbx poly seq scheme: B,2,LYS,214

2,PRO,215
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 215
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,215
referenced by pdbx poly seq scheme: B,2,PRO,215

2,CYS,216
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: CYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: CYS
entity poly seq.num: 216
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,CYS,216
referenced by pdbx poly seq scheme: B,2,CYS,216

2,LEU,217
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 217
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,217
referenced by pdbx poly seq scheme: B,2,LEU,217

2,MET,218
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: MET
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: MET
entity poly seq.num: 218
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,MET,218
referenced by pdbx poly seq scheme: B,2,MET,218

2,ASP,219
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASP
entity poly seq.num: 219
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASP,219
referenced by pdbx poly seq scheme: B,2,ASP,219

2,LEU,220
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 220
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,220
referenced by pdbx poly seq scheme: B,2,LEU,220

2,HIS,221
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 221
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,221
referenced by pdbx poly seq scheme: B,2,HIS,221

2,GLN,222
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 222
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,222
referenced by pdbx poly seq scheme: B,2,GLN,222

2,THR,223
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 223
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,223
referenced by pdbx poly seq scheme: B,2,THR,223

2,TYR,224
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 224
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,224
referenced by pdbx poly seq scheme: B,2,TYR,224

2,LEU,225
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 225
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,225
referenced by pdbx poly seq scheme: B,2,LEU,225

2,LYS,226
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 226
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,226
referenced by pdbx poly seq scheme: B,2,LYS,226

2,ALA,227
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 227
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,227
referenced by pdbx poly seq scheme: B,2,ALA,227

2,PRO,228
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 228
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,228
referenced by pdbx poly seq scheme: B,2,PRO,228

2,GLN,229
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 229
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,229
referenced by pdbx poly seq scheme: B,2,GLN,229

2,HIS,230
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 230
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,230
referenced by pdbx poly seq scheme: B,2,HIS,230

2,ALA,231
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ALA
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ALA
entity poly seq.num: 231
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ALA,231
referenced by pdbx poly seq scheme: B,2,ALA,231

2,GLN,232
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 232
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,232
referenced by pdbx poly seq scheme: B,2,GLN,232

2,GLN,233
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLN
entity poly seq.num: 233
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLN,233
referenced by pdbx poly seq scheme: B,2,GLN,233

2,SER,234
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 234
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,234
referenced by pdbx poly seq scheme: B,2,SER,234

2,ILE,235
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ILE
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ILE
entity poly seq.num: 235
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ILE,235
referenced by pdbx poly seq scheme: B,2,ILE,235

2,ARG,236
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ARG
entity poly seq.num: 236
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ARG,236
referenced by pdbx poly seq scheme: B,2,ARG,236

2,GLU,237
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 237
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,237
referenced by pdbx poly seq scheme: B,2,GLU,237

2,LYS,238
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 238
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,238
referenced by pdbx poly seq scheme: B,2,LYS,238

2,TYR,239
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 239
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,239
referenced by pdbx poly seq scheme: B,2,TYR,239

2,LYS,240
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 240
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,240
referenced by pdbx poly seq scheme: B,2,LYS,240

2,ASN,241
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 241
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,241
referenced by pdbx poly seq scheme: B,2,ASN,241

2,SER,242
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 242
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,242
referenced by pdbx poly seq scheme: B,2,SER,242

2,LYS,243
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LYS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LYS
entity poly seq.num: 243
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LYS,243
referenced by pdbx poly seq scheme: B,2,LYS,243

2,TYR,244
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: TYR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: TYR
entity poly seq.num: 244
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,TYR,244
referenced by pdbx poly seq scheme: B,2,TYR,244

2,HIS,245
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: HIS
entity poly seq.num: 245
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,HIS,245
referenced by pdbx poly seq scheme: B,2,HIS,245

2,GLY,246
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLY
entity poly seq.num: 246
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLY,246
referenced by pdbx poly seq scheme: B,2,GLY,246

2,VAL,247
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: VAL
entity poly seq.num: 247
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,VAL,247
referenced by pdbx poly seq scheme: B,2,VAL,247

2,SER,248
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: SER
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: SER
entity poly seq.num: 248
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,SER,248
referenced by pdbx poly seq scheme: B,2,SER,248

2,LEU,249
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 249
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,249
referenced by pdbx poly seq scheme: B,2,LEU,249

2,LEU,250
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 250
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,250
referenced by pdbx poly seq scheme: B,2,LEU,250

2,ASN,251
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 251
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,251
referenced by pdbx poly seq scheme: B,2,ASN,251

2,PRO,252
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 252
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,252
referenced by pdbx poly seq scheme: B,2,PRO,252

2,PRO,253
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: PRO
entity poly seq.num: 253
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,PRO,253
referenced by pdbx poly seq scheme: B,2,PRO,253

2,GLU,254
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: GLU
entity poly seq.num: 254
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,GLU,254
referenced by pdbx poly seq scheme: B,2,GLU,254

2,THR,255
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: THR
entity poly seq.num: 255
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,THR,255
referenced by pdbx poly seq scheme: B,2,THR,255

2,LEU,256
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 256
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,256
referenced by pdbx poly seq scheme: B,2,LEU,256

2,ASN,257
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASN
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: ASN
entity poly seq.num: 257
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,ASN,257
referenced by pdbx poly seq scheme: B,2,ASN,257

2,LEU,258
type: entity poly seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
reference to entity poly: http://rdf.wwpdb.org/pdb/4CFN/entity_poly/2
entity poly seq.entity id: 2
entity poly seq.mon id: LEU
entity poly seq.num: 258
entity poly seq.hetero: n
referenced by pdbx poly seq scheme: D,2,LEU,258
referenced by pdbx poly seq scheme: B,2,LEU,258

1,1
type: entity src gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/1
entity src gen.entity id: 1
entity src gen.pdbx src id: 1
entity src gen.gene src common name: HUMAN
entity src gen.pdbx alt source flag: sample
entity src gen.pdbx gene src ncbi taxonomy id: 9606
entity src gen.pdbx gene src scientific name: HOMO SAPIENS
entity src gen.pdbx host org ncbi taxonomy id: 37762
entity src gen.pdbx host org scientific name: ESCHERICHIA COLI B
entity src gen.pdbx host org strain: B834
entity src gen.pdbx host org vector: PGEX-6P-1
entity src gen.pdbx host org vector type: PLASMID
link to taxonomy source: taxonomy:9606
link to taxonomy host: taxonomy:37762

taxonomy:9606

taxonomy:37762

2,1
type: entity src gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/2
entity src gen.entity id: 2
entity src gen.pdbx src id: 1
entity src gen.gene src common name: HUMAN
entity src gen.pdbx alt source flag: sample
entity src gen.pdbx gene src ncbi taxonomy id: 9606
entity src gen.pdbx gene src scientific name: HOMO SAPIENS
entity src gen.pdbx host org ncbi taxonomy id: 37762
entity src gen.pdbx host org scientific name: ESCHERICHIA COLI B
entity src gen.pdbx host org strain: B834
entity src gen.pdbx host org vector: PET21D
entity src gen.pdbx host org vector type: PLASMID
link to taxonomy source: taxonomy:9606
link to taxonomy host: taxonomy:37762

4CFN,X-RAY DIFFRACTION
type: exptl
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
exptl.entry id: 4CFN
exptl.method: X-RAY DIFFRACTION
exptl.crystals number: 1

http://rdf.wwpdb.org/pdb/4CFN/exptl_crystal_grow/1
type: exptl crystal grow
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to exptl crystal: http://rdf.wwpdb.org/pdb/4CFN/exptl_crystal/1
exptl crystal grow.crystal id: 1
exptl crystal grow.pdbx details: 50 MM AMMONIUM ACETATE, 10% PEG-3350, 15 MM NACL, 100 MM HEPES, PH = 7.4, 10% DMSO

Structure model,1,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 1
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: chem_comp_atom

Structure model,3
referenced by pdbx audit revision category: Structure model,1,3
referenced by pdbx audit revision category: Structure model,2,3
referenced by pdbx audit revision category: Structure model,3,3
referenced by pdbx audit revision category: Structure model,4,3
referenced by pdbx audit revision category: Structure model,5,3
referenced by pdbx audit revision category: Structure model,6,3
referenced by pdbx audit revision category: Structure model,7,3
referenced by pdbx audit revision group: Structure model,2,3
referenced by pdbx audit revision group: Structure model,3,3
referenced by pdbx audit revision group: Structure model,4,3
referenced by pdbx audit revision group: Structure model,5,3
referenced by pdbx audit revision group: Structure model,6,3
type: pdbx audit revision history
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 3
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 2
pdbx audit revision history.revision date: 2023-12-20
referenced by pdbx audit revision item: Structure model,7,3
referenced by pdbx audit revision item: Structure model,1,3
referenced by pdbx audit revision item: Structure model,2,3
referenced by pdbx audit revision item: Structure model,3,3
referenced by pdbx audit revision item: Structure model,4,3
referenced by pdbx audit revision item: Structure model,5,3
referenced by pdbx audit revision item: Structure model,6,3

Structure model,2,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 2
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: chem_comp_bond

Structure model,3,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 3
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: database_2

Structure model,4,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 4
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: pdbx_database_status

Structure model,5,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 5
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: pdbx_initial_refinement_model

Structure model,6,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 6
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: struct_conn

Structure model,7,3
type: pdbx audit revision category
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision category.data content type: Structure model
pdbx audit revision category.ordinal: 7
pdbx audit revision category.revision ordinal: 3
pdbx audit revision category.category: struct_site

Structure model,1,1
type: pdbx audit revision details
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,1
pdbx audit revision details.data content type: Structure model
pdbx audit revision details.ordinal: 1
pdbx audit revision details.revision ordinal: 1
pdbx audit revision details.provider: repository
pdbx audit revision details.type: Initial release

Structure model,1
referenced by pdbx audit revision details: Structure model,1,1
type: pdbx audit revision history
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 1
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 0
pdbx audit revision history.revision date: 2013-12-18

Structure model,1,2
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,2
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 1
pdbx audit revision group.revision ordinal: 2
pdbx audit revision group.group: Database references

Structure model,2
referenced by pdbx audit revision group: Structure model,1,2
type: pdbx audit revision history
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx audit revision history.data content type: Structure model
pdbx audit revision history.ordinal: 2
pdbx audit revision history.major revision: 1
pdbx audit revision history.minor revision: 1
pdbx audit revision history.revision date: 2014-02-12

Structure model,2,3
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 2
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Data collection

Structure model,3,3
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 3
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Database references

Structure model,4,3
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 4
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Derived calculations

Structure model,5,3
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 5
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Other

Structure model,6,3
type: pdbx audit revision group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision group.data content type: Structure model
pdbx audit revision group.ordinal: 6
pdbx audit revision group.revision ordinal: 3
pdbx audit revision group.group: Refinement description

Structure model,1,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 1
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _database_2.pdbx_DOI

Structure model,2,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 2
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _database_2.pdbx_database_accession

Structure model,3,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 3
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _pdbx_database_status.status_code_sf

Structure model,4,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 4
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _struct_conn.pdbx_leaving_atom_flag

Structure model,5,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 5
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _struct_site.pdbx_auth_asym_id

Structure model,6,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 6
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _struct_site.pdbx_auth_comp_id

Structure model,7,3
type: pdbx audit revision item
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx audit revision history: Structure model,3
pdbx audit revision item.data content type: Structure model
pdbx audit revision item.ordinal: 7
pdbx audit revision item.revision ordinal: 3
pdbx audit revision item.item: _struct_site.pdbx_auth_seq_id

unspecified,1W8C,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 1W8C
pdbx database related.db name: PDB
pdbx database related.details: CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL -9H-PURIN-2-YLAMINE AND MONOMERIC CDK2

unspecified,4CFM,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 4CFM
pdbx database related.db name: PDB
pdbx database related.details: STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.

unspecified,4CFU,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 4CFU
pdbx database related.db name: PDB
pdbx database related.details: STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.

unspecified,4CFV,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 4CFV
pdbx database related.db name: PDB
pdbx database related.details: STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.

unspecified,4CFW,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 4CFW
pdbx database related.db name: PDB
pdbx database related.details: STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.

unspecified,4CFX,PDB
type: pdbx database related
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx database related.content type: unspecified
pdbx database related.db id: 4CFX
pdbx database related.db name: PDB
pdbx database related.details: STRUCTURE-BASED DESIGN OF C8-SUBSTITUTED O6- CYCLOHEXYLMETHOXYGUANINE CDK1 AND 2 INHIBITORS.

4CFN
type: pdbx database status
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
pdbx database status.entry id: 4CFN
pdbx database status.deposit site: PDBE
pdbx database status.pdb format compatible: Y
pdbx database status.process site: PDBE
pdbx database status.recvd initial deposition date: 2013-11-19
pdbx database status.status code: REL
pdbx database status.status code sf: REL

http://rdf.wwpdb.org/pdb/4CFN/pdbx_entity_nonpoly/3
type: pdbx entity nonpoly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/3
pdbx entity nonpoly.entity id: 3
pdbx entity nonpoly.comp id: JYM
pdbx entity nonpoly.name: 6-(cyclohexylmethoxy)-8-(trifluoromethyl)-9H-purin-2-amine

http://rdf.wwpdb.org/pdb/4CFN/pdbx_entity_nonpoly/4
type: pdbx entity nonpoly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/4
pdbx entity nonpoly.entity id: 4
pdbx entity nonpoly.comp id: DTT
pdbx entity nonpoly.name: 2,3-DIHYDROXY-1,4-DITHIOBUTANE

http://rdf.wwpdb.org/pdb/4CFN/pdbx_entity_nonpoly/5
type: pdbx entity nonpoly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/5
pdbx entity nonpoly.entity id: 5
pdbx entity nonpoly.comp id: HOH
pdbx entity nonpoly.name: water

4CFN
type: pdbx entry details
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
pdbx entry details.entry id: 4CFN
pdbx entry details.sequence details: N-TERMINAL 3C PROTEASE SITE

http://rdf.wwpdb.org/pdb/4CFN/pdbx_initial_refinement_model/1
type: pdbx initial refinement model
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx initial refinement model.id: 1
pdbx initial refinement model.accession code: 1H1S
pdbx initial refinement model.details: PDB ENTRY 1H1S
pdbx initial refinement model.source name: PDB
pdbx initial refinement model.type: experimental model

E,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: E
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: JYM
pdbx nonpoly scheme.auth seq num: 1298
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: JYM
pdbx nonpoly scheme.pdb mon id: JYM
pdbx nonpoly scheme.pdb seq num: 1298
pdbx nonpoly scheme.pdb strand id: A

F,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: F
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: DTT
pdbx nonpoly scheme.auth seq num: 1433
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: DTT
pdbx nonpoly scheme.pdb mon id: DTT
pdbx nonpoly scheme.pdb seq num: 1433
pdbx nonpoly scheme.pdb strand id: B

G,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: G
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: JYM
pdbx nonpoly scheme.auth seq num: 1295
pdbx nonpoly scheme.entity id: 3
pdbx nonpoly scheme.mon id: JYM
pdbx nonpoly scheme.pdb mon id: JYM
pdbx nonpoly scheme.pdb seq num: 1295
pdbx nonpoly scheme.pdb strand id: C

H,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: H
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: DTT
pdbx nonpoly scheme.auth seq num: 1433
pdbx nonpoly scheme.entity id: 4
pdbx nonpoly scheme.mon id: DTT
pdbx nonpoly scheme.pdb mon id: DTT
pdbx nonpoly scheme.pdb seq num: 1433
pdbx nonpoly scheme.pdb strand id: D

I,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2001
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2001
pdbx nonpoly scheme.pdb strand id: A

I,2
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2002
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2002
pdbx nonpoly scheme.pdb strand id: A

I,3
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2003
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2003
pdbx nonpoly scheme.pdb strand id: A

I,4
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2004
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2004
pdbx nonpoly scheme.pdb strand id: A

I,5
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2005
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2005
pdbx nonpoly scheme.pdb strand id: A

I,6
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2006
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2006
pdbx nonpoly scheme.pdb strand id: A

I,7
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2007
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2007
pdbx nonpoly scheme.pdb strand id: A

I,8
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2008
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2008
pdbx nonpoly scheme.pdb strand id: A

I,9
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2009
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2009
pdbx nonpoly scheme.pdb strand id: A

I,10
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2010
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2010
pdbx nonpoly scheme.pdb strand id: A

I,11
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2011
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2011
pdbx nonpoly scheme.pdb strand id: A

I,12
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2012
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2012
pdbx nonpoly scheme.pdb strand id: A

I,13
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2013
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2013
pdbx nonpoly scheme.pdb strand id: A

I,14
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2014
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2014
pdbx nonpoly scheme.pdb strand id: A

I,15
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2015
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2015
pdbx nonpoly scheme.pdb strand id: A

I,16
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2016
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2016
pdbx nonpoly scheme.pdb strand id: A

I,17
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2017
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2017
pdbx nonpoly scheme.pdb strand id: A

I,18
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2018
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2018
pdbx nonpoly scheme.pdb strand id: A

I,19
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2019
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2019
pdbx nonpoly scheme.pdb strand id: A

I,20
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2020
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2020
pdbx nonpoly scheme.pdb strand id: A

I,21
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2021
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2021
pdbx nonpoly scheme.pdb strand id: A

I,22
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2022
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2022
pdbx nonpoly scheme.pdb strand id: A

I,23
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2023
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2023
pdbx nonpoly scheme.pdb strand id: A

I,24
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2024
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2024
pdbx nonpoly scheme.pdb strand id: A

I,25
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2025
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2025
pdbx nonpoly scheme.pdb strand id: A

I,26
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2026
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2026
pdbx nonpoly scheme.pdb strand id: A

I,27
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2027
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2027
pdbx nonpoly scheme.pdb strand id: A

I,28
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2028
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2028
pdbx nonpoly scheme.pdb strand id: A

I,29
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2029
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2029
pdbx nonpoly scheme.pdb strand id: A

I,30
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2030
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2030
pdbx nonpoly scheme.pdb strand id: A

I,31
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2031
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2031
pdbx nonpoly scheme.pdb strand id: A

I,32
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2032
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2032
pdbx nonpoly scheme.pdb strand id: A

I,33
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2033
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2033
pdbx nonpoly scheme.pdb strand id: A

I,34
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2034
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2034
pdbx nonpoly scheme.pdb strand id: A

I,35
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2035
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2035
pdbx nonpoly scheme.pdb strand id: A

I,36
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2036
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2036
pdbx nonpoly scheme.pdb strand id: A

I,37
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2037
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2037
pdbx nonpoly scheme.pdb strand id: A

I,38
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2038
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2038
pdbx nonpoly scheme.pdb strand id: A

I,39
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2039
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2039
pdbx nonpoly scheme.pdb strand id: A

I,40
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2040
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2040
pdbx nonpoly scheme.pdb strand id: A

I,41
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2041
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2041
pdbx nonpoly scheme.pdb strand id: A

I,42
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2042
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2042
pdbx nonpoly scheme.pdb strand id: A

I,43
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2043
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2043
pdbx nonpoly scheme.pdb strand id: A

I,44
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2044
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2044
pdbx nonpoly scheme.pdb strand id: A

I,45
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2045
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2045
pdbx nonpoly scheme.pdb strand id: A

I,46
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2046
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2046
pdbx nonpoly scheme.pdb strand id: A

I,47
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2047
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2047
pdbx nonpoly scheme.pdb strand id: A

I,48
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2048
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2048
pdbx nonpoly scheme.pdb strand id: A

I,49
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2049
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2049
pdbx nonpoly scheme.pdb strand id: A

I,50
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2050
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2050
pdbx nonpoly scheme.pdb strand id: A

I,51
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2051
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2051
pdbx nonpoly scheme.pdb strand id: A

I,52
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2052
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2052
pdbx nonpoly scheme.pdb strand id: A

I,53
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2053
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2053
pdbx nonpoly scheme.pdb strand id: A

I,54
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2054
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2054
pdbx nonpoly scheme.pdb strand id: A

I,55
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2055
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2055
pdbx nonpoly scheme.pdb strand id: A

I,56
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2056
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2056
pdbx nonpoly scheme.pdb strand id: A

I,57
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2057
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2057
pdbx nonpoly scheme.pdb strand id: A

I,58
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2058
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2058
pdbx nonpoly scheme.pdb strand id: A

I,59
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2059
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2059
pdbx nonpoly scheme.pdb strand id: A

I,60
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2060
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2060
pdbx nonpoly scheme.pdb strand id: A

I,61
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2061
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2061
pdbx nonpoly scheme.pdb strand id: A

I,62
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2062
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2062
pdbx nonpoly scheme.pdb strand id: A

I,63
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2063
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2063
pdbx nonpoly scheme.pdb strand id: A

I,64
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2064
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2064
pdbx nonpoly scheme.pdb strand id: A

I,65
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2065
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2065
pdbx nonpoly scheme.pdb strand id: A

I,66
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2066
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2066
pdbx nonpoly scheme.pdb strand id: A

I,67
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2067
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2067
pdbx nonpoly scheme.pdb strand id: A

I,68
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2068
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2068
pdbx nonpoly scheme.pdb strand id: A

I,69
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2069
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2069
pdbx nonpoly scheme.pdb strand id: A

I,70
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2070
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2070
pdbx nonpoly scheme.pdb strand id: A

I,71
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2071
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2071
pdbx nonpoly scheme.pdb strand id: A

I,72
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2072
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2072
pdbx nonpoly scheme.pdb strand id: A

I,73
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2073
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2073
pdbx nonpoly scheme.pdb strand id: A

I,74
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2074
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2074
pdbx nonpoly scheme.pdb strand id: A

I,75
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2075
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2075
pdbx nonpoly scheme.pdb strand id: A

I,76
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2076
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2076
pdbx nonpoly scheme.pdb strand id: A

I,77
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2077
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2077
pdbx nonpoly scheme.pdb strand id: A

I,78
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2078
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2078
pdbx nonpoly scheme.pdb strand id: A

I,79
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2079
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2079
pdbx nonpoly scheme.pdb strand id: A

I,80
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2080
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2080
pdbx nonpoly scheme.pdb strand id: A

I,81
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2081
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2081
pdbx nonpoly scheme.pdb strand id: A

I,82
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2082
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2082
pdbx nonpoly scheme.pdb strand id: A

I,83
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2083
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2083
pdbx nonpoly scheme.pdb strand id: A

I,84
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2084
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2084
pdbx nonpoly scheme.pdb strand id: A

I,85
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2085
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2085
pdbx nonpoly scheme.pdb strand id: A

I,86
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2086
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2086
pdbx nonpoly scheme.pdb strand id: A

I,87
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2087
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2087
pdbx nonpoly scheme.pdb strand id: A

I,88
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2088
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2088
pdbx nonpoly scheme.pdb strand id: A

I,89
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2089
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2089
pdbx nonpoly scheme.pdb strand id: A

I,90
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2090
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2090
pdbx nonpoly scheme.pdb strand id: A

I,91
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2092
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2092
pdbx nonpoly scheme.pdb strand id: A

I,92
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2093
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2093
pdbx nonpoly scheme.pdb strand id: A

I,93
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2094
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2094
pdbx nonpoly scheme.pdb strand id: A

I,94
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2095
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2095
pdbx nonpoly scheme.pdb strand id: A

I,95
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2096
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2096
pdbx nonpoly scheme.pdb strand id: A

I,96
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2097
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2097
pdbx nonpoly scheme.pdb strand id: A

I,97
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2098
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2098
pdbx nonpoly scheme.pdb strand id: A

I,98
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2099
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2099
pdbx nonpoly scheme.pdb strand id: A

I,99
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2100
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2100
pdbx nonpoly scheme.pdb strand id: A

I,100
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2101
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2101
pdbx nonpoly scheme.pdb strand id: A

I,101
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2102
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2102
pdbx nonpoly scheme.pdb strand id: A

I,102
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2103
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2103
pdbx nonpoly scheme.pdb strand id: A

I,103
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2104
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2104
pdbx nonpoly scheme.pdb strand id: A

I,104
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2105
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2105
pdbx nonpoly scheme.pdb strand id: A

I,105
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2106
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2106
pdbx nonpoly scheme.pdb strand id: A

I,106
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2107
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2107
pdbx nonpoly scheme.pdb strand id: A

I,107
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2108
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2108
pdbx nonpoly scheme.pdb strand id: A

I,108
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2109
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2109
pdbx nonpoly scheme.pdb strand id: A

I,109
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2110
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2110
pdbx nonpoly scheme.pdb strand id: A

I,110
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2111
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2111
pdbx nonpoly scheme.pdb strand id: A

I,111
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2112
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2112
pdbx nonpoly scheme.pdb strand id: A

I,112
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2113
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2113
pdbx nonpoly scheme.pdb strand id: A

I,113
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2114
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2114
pdbx nonpoly scheme.pdb strand id: A

I,114
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2115
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2115
pdbx nonpoly scheme.pdb strand id: A

I,115
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2116
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2116
pdbx nonpoly scheme.pdb strand id: A

I,116
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2117
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2117
pdbx nonpoly scheme.pdb strand id: A

I,117
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2118
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2118
pdbx nonpoly scheme.pdb strand id: A

I,118
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2119
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2119
pdbx nonpoly scheme.pdb strand id: A

I,119
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2120
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2120
pdbx nonpoly scheme.pdb strand id: A

I,120
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2121
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2121
pdbx nonpoly scheme.pdb strand id: A

I,121
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2122
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2122
pdbx nonpoly scheme.pdb strand id: A

I,122
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2123
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2123
pdbx nonpoly scheme.pdb strand id: A

I,123
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2124
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2124
pdbx nonpoly scheme.pdb strand id: A

I,124
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 124
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2125
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2125
pdbx nonpoly scheme.pdb strand id: A

I,125
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 125
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2126
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2126
pdbx nonpoly scheme.pdb strand id: A

I,126
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 126
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2127
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2127
pdbx nonpoly scheme.pdb strand id: A

I,127
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 127
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2128
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2128
pdbx nonpoly scheme.pdb strand id: A

I,128
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 128
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2129
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2129
pdbx nonpoly scheme.pdb strand id: A

I,129
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 129
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2130
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2130
pdbx nonpoly scheme.pdb strand id: A

I,130
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 130
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2131
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2131
pdbx nonpoly scheme.pdb strand id: A

I,131
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 131
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2132
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2132
pdbx nonpoly scheme.pdb strand id: A

I,132
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 132
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2133
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2133
pdbx nonpoly scheme.pdb strand id: A

I,133
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 133
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2134
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2134
pdbx nonpoly scheme.pdb strand id: A

I,134
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 134
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2135
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2135
pdbx nonpoly scheme.pdb strand id: A

I,135
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 135
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2136
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2136
pdbx nonpoly scheme.pdb strand id: A

I,136
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 136
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2137
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2137
pdbx nonpoly scheme.pdb strand id: A

I,137
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 137
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2138
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2138
pdbx nonpoly scheme.pdb strand id: A

I,138
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 138
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2139
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2139
pdbx nonpoly scheme.pdb strand id: A

I,139
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 139
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2140
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2140
pdbx nonpoly scheme.pdb strand id: A

I,140
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 140
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2141
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2141
pdbx nonpoly scheme.pdb strand id: A

I,141
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 141
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2142
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2142
pdbx nonpoly scheme.pdb strand id: A

I,142
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 142
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2143
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2143
pdbx nonpoly scheme.pdb strand id: A

I,143
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 143
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2144
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2144
pdbx nonpoly scheme.pdb strand id: A

I,144
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 144
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2145
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2145
pdbx nonpoly scheme.pdb strand id: A

I,145
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 145
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2146
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2146
pdbx nonpoly scheme.pdb strand id: A

I,146
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 146
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2147
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2147
pdbx nonpoly scheme.pdb strand id: A

I,147
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 147
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2148
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2148
pdbx nonpoly scheme.pdb strand id: A

I,148
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 148
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2149
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2149
pdbx nonpoly scheme.pdb strand id: A

I,149
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 149
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2150
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2150
pdbx nonpoly scheme.pdb strand id: A

I,150
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 150
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2151
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2151
pdbx nonpoly scheme.pdb strand id: A

I,151
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 151
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2152
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2152
pdbx nonpoly scheme.pdb strand id: A

I,152
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 152
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2153
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2153
pdbx nonpoly scheme.pdb strand id: A

I,153
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 153
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2154
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2154
pdbx nonpoly scheme.pdb strand id: A

I,154
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 154
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2155
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2155
pdbx nonpoly scheme.pdb strand id: A

I,155
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 155
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2156
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2156
pdbx nonpoly scheme.pdb strand id: A

I,156
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 156
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2157
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2157
pdbx nonpoly scheme.pdb strand id: A

I,157
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 157
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2158
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2158
pdbx nonpoly scheme.pdb strand id: A

I,158
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 158
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2159
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2159
pdbx nonpoly scheme.pdb strand id: A

I,159
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 159
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2160
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2160
pdbx nonpoly scheme.pdb strand id: A

I,160
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 160
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2161
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2161
pdbx nonpoly scheme.pdb strand id: A

I,161
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 161
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2162
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2162
pdbx nonpoly scheme.pdb strand id: A

I,162
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 162
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2163
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2163
pdbx nonpoly scheme.pdb strand id: A

I,163
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 163
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2164
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2164
pdbx nonpoly scheme.pdb strand id: A

I,164
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 164
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2165
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2165
pdbx nonpoly scheme.pdb strand id: A

I,165
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 165
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2166
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2166
pdbx nonpoly scheme.pdb strand id: A

I,166
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 166
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2167
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2167
pdbx nonpoly scheme.pdb strand id: A

I,167
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 167
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2168
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2168
pdbx nonpoly scheme.pdb strand id: A

I,168
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 168
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2169
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2169
pdbx nonpoly scheme.pdb strand id: A

I,169
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 169
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2170
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2170
pdbx nonpoly scheme.pdb strand id: A

I,170
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 170
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2171
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2171
pdbx nonpoly scheme.pdb strand id: A

I,171
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 171
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2172
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2172
pdbx nonpoly scheme.pdb strand id: A

I,172
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 172
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2173
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2173
pdbx nonpoly scheme.pdb strand id: A

I,173
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 173
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2174
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2174
pdbx nonpoly scheme.pdb strand id: A

I,174
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 174
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2175
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2175
pdbx nonpoly scheme.pdb strand id: A

I,175
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 175
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2176
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2176
pdbx nonpoly scheme.pdb strand id: A

I,176
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 176
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2177
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2177
pdbx nonpoly scheme.pdb strand id: A

I,177
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 177
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2178
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2178
pdbx nonpoly scheme.pdb strand id: A

I,178
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 178
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2179
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2179
pdbx nonpoly scheme.pdb strand id: A

I,179
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 179
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2180
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2180
pdbx nonpoly scheme.pdb strand id: A

I,180
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 180
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2181
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2181
pdbx nonpoly scheme.pdb strand id: A

I,181
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 181
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2182
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2182
pdbx nonpoly scheme.pdb strand id: A

I,182
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 182
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2183
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2183
pdbx nonpoly scheme.pdb strand id: A

I,183
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 183
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2184
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2184
pdbx nonpoly scheme.pdb strand id: A

I,184
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 184
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2185
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2185
pdbx nonpoly scheme.pdb strand id: A

I,185
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 185
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2186
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2186
pdbx nonpoly scheme.pdb strand id: A

I,186
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 186
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2187
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2187
pdbx nonpoly scheme.pdb strand id: A

I,187
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 187
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2188
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2188
pdbx nonpoly scheme.pdb strand id: A

I,188
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 188
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2189
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2189
pdbx nonpoly scheme.pdb strand id: A

I,189
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 189
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2190
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2190
pdbx nonpoly scheme.pdb strand id: A

I,190
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 190
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2191
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2191
pdbx nonpoly scheme.pdb strand id: A

I,191
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 191
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2192
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2192
pdbx nonpoly scheme.pdb strand id: A

I,192
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 192
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2193
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2193
pdbx nonpoly scheme.pdb strand id: A

J,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2001
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2001
pdbx nonpoly scheme.pdb strand id: B

J,2
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2002
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2002
pdbx nonpoly scheme.pdb strand id: B

J,3
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2003
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2003
pdbx nonpoly scheme.pdb strand id: B

J,4
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2004
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2004
pdbx nonpoly scheme.pdb strand id: B

J,5
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2005
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2005
pdbx nonpoly scheme.pdb strand id: B

J,6
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2006
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2006
pdbx nonpoly scheme.pdb strand id: B

J,7
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2007
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2007
pdbx nonpoly scheme.pdb strand id: B

J,8
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2008
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2008
pdbx nonpoly scheme.pdb strand id: B

J,9
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2009
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2009
pdbx nonpoly scheme.pdb strand id: B

J,10
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2010
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2010
pdbx nonpoly scheme.pdb strand id: B

J,11
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2011
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2011
pdbx nonpoly scheme.pdb strand id: B

J,12
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2012
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2012
pdbx nonpoly scheme.pdb strand id: B

J,13
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2013
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2013
pdbx nonpoly scheme.pdb strand id: B

J,14
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2014
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2014
pdbx nonpoly scheme.pdb strand id: B

J,15
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2015
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2015
pdbx nonpoly scheme.pdb strand id: B

J,16
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2016
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2016
pdbx nonpoly scheme.pdb strand id: B

J,17
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2017
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2017
pdbx nonpoly scheme.pdb strand id: B

J,18
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2018
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2018
pdbx nonpoly scheme.pdb strand id: B

J,19
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2019
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2019
pdbx nonpoly scheme.pdb strand id: B

J,20
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2020
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2020
pdbx nonpoly scheme.pdb strand id: B

J,21
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2021
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2021
pdbx nonpoly scheme.pdb strand id: B

J,22
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2022
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2022
pdbx nonpoly scheme.pdb strand id: B

J,23
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2023
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2023
pdbx nonpoly scheme.pdb strand id: B

J,24
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2024
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2024
pdbx nonpoly scheme.pdb strand id: B

J,25
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2025
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2025
pdbx nonpoly scheme.pdb strand id: B

J,26
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2026
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2026
pdbx nonpoly scheme.pdb strand id: B

J,27
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2027
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2027
pdbx nonpoly scheme.pdb strand id: B

J,28
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2028
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2028
pdbx nonpoly scheme.pdb strand id: B

J,29
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2029
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2029
pdbx nonpoly scheme.pdb strand id: B

J,30
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2030
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2030
pdbx nonpoly scheme.pdb strand id: B

J,31
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2031
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2031
pdbx nonpoly scheme.pdb strand id: B

J,32
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2032
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2032
pdbx nonpoly scheme.pdb strand id: B

J,33
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2033
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2033
pdbx nonpoly scheme.pdb strand id: B

J,34
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2034
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2034
pdbx nonpoly scheme.pdb strand id: B

J,35
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2035
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2035
pdbx nonpoly scheme.pdb strand id: B

J,36
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2036
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2036
pdbx nonpoly scheme.pdb strand id: B

J,37
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2037
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2037
pdbx nonpoly scheme.pdb strand id: B

J,38
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2038
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2038
pdbx nonpoly scheme.pdb strand id: B

J,39
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2039
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2039
pdbx nonpoly scheme.pdb strand id: B

J,40
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2040
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2040
pdbx nonpoly scheme.pdb strand id: B

J,41
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2041
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2041
pdbx nonpoly scheme.pdb strand id: B

J,42
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2042
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2042
pdbx nonpoly scheme.pdb strand id: B

J,43
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2043
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2043
pdbx nonpoly scheme.pdb strand id: B

J,44
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2044
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2044
pdbx nonpoly scheme.pdb strand id: B

J,45
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2045
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2045
pdbx nonpoly scheme.pdb strand id: B

J,46
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2046
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2046
pdbx nonpoly scheme.pdb strand id: B

J,47
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2047
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2047
pdbx nonpoly scheme.pdb strand id: B

J,48
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2048
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2048
pdbx nonpoly scheme.pdb strand id: B

J,49
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2049
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2049
pdbx nonpoly scheme.pdb strand id: B

J,50
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2050
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2050
pdbx nonpoly scheme.pdb strand id: B

J,51
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2051
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2051
pdbx nonpoly scheme.pdb strand id: B

J,52
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2052
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2052
pdbx nonpoly scheme.pdb strand id: B

J,53
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2053
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2053
pdbx nonpoly scheme.pdb strand id: B

J,54
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2054
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2054
pdbx nonpoly scheme.pdb strand id: B

J,55
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2055
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2055
pdbx nonpoly scheme.pdb strand id: B

J,56
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2056
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2056
pdbx nonpoly scheme.pdb strand id: B

J,57
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2057
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2057
pdbx nonpoly scheme.pdb strand id: B

J,58
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2058
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2058
pdbx nonpoly scheme.pdb strand id: B

J,59
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2059
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2059
pdbx nonpoly scheme.pdb strand id: B

J,60
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2060
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2060
pdbx nonpoly scheme.pdb strand id: B

J,61
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2061
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2061
pdbx nonpoly scheme.pdb strand id: B

J,62
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2062
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2062
pdbx nonpoly scheme.pdb strand id: B

J,63
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2063
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2063
pdbx nonpoly scheme.pdb strand id: B

J,64
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2064
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2064
pdbx nonpoly scheme.pdb strand id: B

J,65
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2065
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2065
pdbx nonpoly scheme.pdb strand id: B

J,66
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2066
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2066
pdbx nonpoly scheme.pdb strand id: B

J,67
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2067
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2067
pdbx nonpoly scheme.pdb strand id: B

J,68
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2068
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2068
pdbx nonpoly scheme.pdb strand id: B

J,69
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2069
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2069
pdbx nonpoly scheme.pdb strand id: B

J,70
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2070
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2070
pdbx nonpoly scheme.pdb strand id: B

J,71
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2071
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2071
pdbx nonpoly scheme.pdb strand id: B

J,72
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2072
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2072
pdbx nonpoly scheme.pdb strand id: B

J,73
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2073
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2073
pdbx nonpoly scheme.pdb strand id: B

J,74
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2074
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2074
pdbx nonpoly scheme.pdb strand id: B

J,75
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2075
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2075
pdbx nonpoly scheme.pdb strand id: B

J,76
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2076
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2076
pdbx nonpoly scheme.pdb strand id: B

J,77
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2077
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2077
pdbx nonpoly scheme.pdb strand id: B

J,78
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2078
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2078
pdbx nonpoly scheme.pdb strand id: B

J,79
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2079
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2079
pdbx nonpoly scheme.pdb strand id: B

J,80
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2080
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2080
pdbx nonpoly scheme.pdb strand id: B

J,81
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2081
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2081
pdbx nonpoly scheme.pdb strand id: B

J,82
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2082
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2082
pdbx nonpoly scheme.pdb strand id: B

J,83
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2083
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2083
pdbx nonpoly scheme.pdb strand id: B

J,84
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2084
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2084
pdbx nonpoly scheme.pdb strand id: B

J,85
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2085
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2085
pdbx nonpoly scheme.pdb strand id: B

J,86
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2086
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2086
pdbx nonpoly scheme.pdb strand id: B

J,87
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2087
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2087
pdbx nonpoly scheme.pdb strand id: B

J,88
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2088
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2088
pdbx nonpoly scheme.pdb strand id: B

J,89
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2089
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2089
pdbx nonpoly scheme.pdb strand id: B

J,90
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2090
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2090
pdbx nonpoly scheme.pdb strand id: B

J,91
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2091
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2091
pdbx nonpoly scheme.pdb strand id: B

J,92
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2092
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2092
pdbx nonpoly scheme.pdb strand id: B

J,93
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2093
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2093
pdbx nonpoly scheme.pdb strand id: B

J,94
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2094
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2094
pdbx nonpoly scheme.pdb strand id: B

J,95
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2095
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2095
pdbx nonpoly scheme.pdb strand id: B

J,96
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2096
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2096
pdbx nonpoly scheme.pdb strand id: B

J,97
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2097
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2097
pdbx nonpoly scheme.pdb strand id: B

J,98
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2098
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2098
pdbx nonpoly scheme.pdb strand id: B

J,99
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2099
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2099
pdbx nonpoly scheme.pdb strand id: B

J,100
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2100
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2100
pdbx nonpoly scheme.pdb strand id: B

J,101
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2101
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2101
pdbx nonpoly scheme.pdb strand id: B

J,102
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2102
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2102
pdbx nonpoly scheme.pdb strand id: B

J,103
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2103
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2103
pdbx nonpoly scheme.pdb strand id: B

J,104
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2104
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2104
pdbx nonpoly scheme.pdb strand id: B

J,105
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2105
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2105
pdbx nonpoly scheme.pdb strand id: B

J,106
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2106
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2106
pdbx nonpoly scheme.pdb strand id: B

J,107
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2107
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2107
pdbx nonpoly scheme.pdb strand id: B

J,108
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2108
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2108
pdbx nonpoly scheme.pdb strand id: B

J,109
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2109
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2109
pdbx nonpoly scheme.pdb strand id: B

J,110
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2110
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2110
pdbx nonpoly scheme.pdb strand id: B

J,111
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2111
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2111
pdbx nonpoly scheme.pdb strand id: B

J,112
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2112
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2112
pdbx nonpoly scheme.pdb strand id: B

J,113
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2113
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2113
pdbx nonpoly scheme.pdb strand id: B

J,114
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2114
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2114
pdbx nonpoly scheme.pdb strand id: B

J,115
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2115
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2115
pdbx nonpoly scheme.pdb strand id: B

J,116
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2116
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2116
pdbx nonpoly scheme.pdb strand id: B

J,117
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2117
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2117
pdbx nonpoly scheme.pdb strand id: B

J,118
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2118
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2118
pdbx nonpoly scheme.pdb strand id: B

J,119
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2119
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2119
pdbx nonpoly scheme.pdb strand id: B

J,120
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2120
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2120
pdbx nonpoly scheme.pdb strand id: B

J,121
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2121
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2121
pdbx nonpoly scheme.pdb strand id: B

J,122
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2122
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2122
pdbx nonpoly scheme.pdb strand id: B

J,123
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2123
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2123
pdbx nonpoly scheme.pdb strand id: B

J,124
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 124
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2124
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2124
pdbx nonpoly scheme.pdb strand id: B

J,125
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 125
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2125
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2125
pdbx nonpoly scheme.pdb strand id: B

J,126
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 126
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2126
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2126
pdbx nonpoly scheme.pdb strand id: B

J,127
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 127
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2127
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2127
pdbx nonpoly scheme.pdb strand id: B

J,128
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 128
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2128
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2128
pdbx nonpoly scheme.pdb strand id: B

J,129
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 129
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2129
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2129
pdbx nonpoly scheme.pdb strand id: B

J,130
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 130
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2130
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2130
pdbx nonpoly scheme.pdb strand id: B

J,131
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 131
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2131
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2131
pdbx nonpoly scheme.pdb strand id: B

J,132
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 132
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2132
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2132
pdbx nonpoly scheme.pdb strand id: B

J,133
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 133
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2133
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2133
pdbx nonpoly scheme.pdb strand id: B

J,134
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 134
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2134
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2134
pdbx nonpoly scheme.pdb strand id: B

J,135
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 135
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2135
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2135
pdbx nonpoly scheme.pdb strand id: B

J,136
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 136
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2136
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2136
pdbx nonpoly scheme.pdb strand id: B

J,137
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 137
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2137
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2137
pdbx nonpoly scheme.pdb strand id: B

J,138
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 138
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2138
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2138
pdbx nonpoly scheme.pdb strand id: B

J,139
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 139
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2139
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2139
pdbx nonpoly scheme.pdb strand id: B

J,140
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 140
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2140
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2140
pdbx nonpoly scheme.pdb strand id: B

J,141
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 141
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2141
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2141
pdbx nonpoly scheme.pdb strand id: B

J,142
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 142
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2142
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2142
pdbx nonpoly scheme.pdb strand id: B

J,143
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 143
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2143
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2143
pdbx nonpoly scheme.pdb strand id: B

J,144
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 144
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2144
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2144
pdbx nonpoly scheme.pdb strand id: B

J,145
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 145
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2145
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2145
pdbx nonpoly scheme.pdb strand id: B

J,146
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 146
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2146
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2146
pdbx nonpoly scheme.pdb strand id: B

J,147
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 147
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2147
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2147
pdbx nonpoly scheme.pdb strand id: B

J,148
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 148
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2148
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2148
pdbx nonpoly scheme.pdb strand id: B

J,149
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 149
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2149
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2149
pdbx nonpoly scheme.pdb strand id: B

J,150
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 150
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2150
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2150
pdbx nonpoly scheme.pdb strand id: B

J,151
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 151
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2151
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2151
pdbx nonpoly scheme.pdb strand id: B

K,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2001
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2001
pdbx nonpoly scheme.pdb strand id: C

K,2
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2002
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2002
pdbx nonpoly scheme.pdb strand id: C

K,3
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2003
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2003
pdbx nonpoly scheme.pdb strand id: C

K,4
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2004
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2004
pdbx nonpoly scheme.pdb strand id: C

K,5
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2005
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2005
pdbx nonpoly scheme.pdb strand id: C

K,6
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2006
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2006
pdbx nonpoly scheme.pdb strand id: C

K,7
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2007
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2007
pdbx nonpoly scheme.pdb strand id: C

K,8
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2008
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2008
pdbx nonpoly scheme.pdb strand id: C

K,9
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2009
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2009
pdbx nonpoly scheme.pdb strand id: C

K,10
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2010
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2010
pdbx nonpoly scheme.pdb strand id: C

K,11
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2011
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2011
pdbx nonpoly scheme.pdb strand id: C

K,12
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2012
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2012
pdbx nonpoly scheme.pdb strand id: C

K,13
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2013
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2013
pdbx nonpoly scheme.pdb strand id: C

K,14
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2014
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2014
pdbx nonpoly scheme.pdb strand id: C

K,15
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2015
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2015
pdbx nonpoly scheme.pdb strand id: C

K,16
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2016
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2016
pdbx nonpoly scheme.pdb strand id: C

K,17
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2017
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2017
pdbx nonpoly scheme.pdb strand id: C

K,18
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2018
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2018
pdbx nonpoly scheme.pdb strand id: C

K,19
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2019
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2019
pdbx nonpoly scheme.pdb strand id: C

K,20
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2020
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2020
pdbx nonpoly scheme.pdb strand id: C

K,21
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2021
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2021
pdbx nonpoly scheme.pdb strand id: C

K,22
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2022
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2022
pdbx nonpoly scheme.pdb strand id: C

K,23
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2023
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2023
pdbx nonpoly scheme.pdb strand id: C

K,24
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2024
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2024
pdbx nonpoly scheme.pdb strand id: C

K,25
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2025
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2025
pdbx nonpoly scheme.pdb strand id: C

K,26
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2026
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2026
pdbx nonpoly scheme.pdb strand id: C

K,27
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2027
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2027
pdbx nonpoly scheme.pdb strand id: C

K,28
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2028
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2028
pdbx nonpoly scheme.pdb strand id: C

K,29
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2029
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2029
pdbx nonpoly scheme.pdb strand id: C

K,30
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2030
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2030
pdbx nonpoly scheme.pdb strand id: C

K,31
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2031
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2031
pdbx nonpoly scheme.pdb strand id: C

K,32
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2032
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2032
pdbx nonpoly scheme.pdb strand id: C

K,33
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2033
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2033
pdbx nonpoly scheme.pdb strand id: C

K,34
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2034
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2034
pdbx nonpoly scheme.pdb strand id: C

K,35
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2035
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2035
pdbx nonpoly scheme.pdb strand id: C

K,36
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2036
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2036
pdbx nonpoly scheme.pdb strand id: C

K,37
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2037
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2037
pdbx nonpoly scheme.pdb strand id: C

K,38
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2038
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2038
pdbx nonpoly scheme.pdb strand id: C

K,39
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2039
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2039
pdbx nonpoly scheme.pdb strand id: C

K,40
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2040
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2040
pdbx nonpoly scheme.pdb strand id: C

K,41
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2041
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2041
pdbx nonpoly scheme.pdb strand id: C

K,42
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2042
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2042
pdbx nonpoly scheme.pdb strand id: C

K,43
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2043
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2043
pdbx nonpoly scheme.pdb strand id: C

K,44
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2044
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2044
pdbx nonpoly scheme.pdb strand id: C

K,45
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2045
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2045
pdbx nonpoly scheme.pdb strand id: C

K,46
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2046
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2046
pdbx nonpoly scheme.pdb strand id: C

K,47
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2047
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2047
pdbx nonpoly scheme.pdb strand id: C

K,48
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2048
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2048
pdbx nonpoly scheme.pdb strand id: C

K,49
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2049
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2049
pdbx nonpoly scheme.pdb strand id: C

K,50
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2050
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2050
pdbx nonpoly scheme.pdb strand id: C

K,51
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2051
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2051
pdbx nonpoly scheme.pdb strand id: C

K,52
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2052
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2052
pdbx nonpoly scheme.pdb strand id: C

K,53
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2053
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2053
pdbx nonpoly scheme.pdb strand id: C

K,54
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2054
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2054
pdbx nonpoly scheme.pdb strand id: C

K,55
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2055
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2055
pdbx nonpoly scheme.pdb strand id: C

K,56
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2056
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2056
pdbx nonpoly scheme.pdb strand id: C

K,57
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2057
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2057
pdbx nonpoly scheme.pdb strand id: C

K,58
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2058
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2058
pdbx nonpoly scheme.pdb strand id: C

K,59
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2059
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2059
pdbx nonpoly scheme.pdb strand id: C

K,60
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2060
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2060
pdbx nonpoly scheme.pdb strand id: C

K,61
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2061
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2061
pdbx nonpoly scheme.pdb strand id: C

K,62
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2062
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2062
pdbx nonpoly scheme.pdb strand id: C

K,63
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2063
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2063
pdbx nonpoly scheme.pdb strand id: C

K,64
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2064
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2064
pdbx nonpoly scheme.pdb strand id: C

K,65
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2065
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2065
pdbx nonpoly scheme.pdb strand id: C

K,66
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2066
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2066
pdbx nonpoly scheme.pdb strand id: C

K,67
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2067
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2067
pdbx nonpoly scheme.pdb strand id: C

K,68
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2068
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2068
pdbx nonpoly scheme.pdb strand id: C

K,69
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2069
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2069
pdbx nonpoly scheme.pdb strand id: C

K,70
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2070
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2070
pdbx nonpoly scheme.pdb strand id: C

K,71
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2071
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2071
pdbx nonpoly scheme.pdb strand id: C

K,72
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2072
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2072
pdbx nonpoly scheme.pdb strand id: C

K,73
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2073
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2073
pdbx nonpoly scheme.pdb strand id: C

K,74
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2074
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2074
pdbx nonpoly scheme.pdb strand id: C

K,75
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2075
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2075
pdbx nonpoly scheme.pdb strand id: C

K,76
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2076
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2076
pdbx nonpoly scheme.pdb strand id: C

K,77
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2077
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2077
pdbx nonpoly scheme.pdb strand id: C

K,78
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2078
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2078
pdbx nonpoly scheme.pdb strand id: C

K,79
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2079
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2079
pdbx nonpoly scheme.pdb strand id: C

K,80
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2080
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2080
pdbx nonpoly scheme.pdb strand id: C

K,81
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2081
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2081
pdbx nonpoly scheme.pdb strand id: C

K,82
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2082
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2082
pdbx nonpoly scheme.pdb strand id: C

K,83
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2083
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2083
pdbx nonpoly scheme.pdb strand id: C

K,84
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2084
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2084
pdbx nonpoly scheme.pdb strand id: C

K,85
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2085
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2085
pdbx nonpoly scheme.pdb strand id: C

K,86
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2086
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2086
pdbx nonpoly scheme.pdb strand id: C

K,87
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2087
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2087
pdbx nonpoly scheme.pdb strand id: C

K,88
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2088
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2088
pdbx nonpoly scheme.pdb strand id: C

K,89
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2089
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2089
pdbx nonpoly scheme.pdb strand id: C

K,90
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 90
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2090
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2090
pdbx nonpoly scheme.pdb strand id: C

K,91
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 91
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2091
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2091
pdbx nonpoly scheme.pdb strand id: C

K,92
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 92
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2092
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2092
pdbx nonpoly scheme.pdb strand id: C

K,93
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 93
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2093
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2093
pdbx nonpoly scheme.pdb strand id: C

K,94
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 94
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2094
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2094
pdbx nonpoly scheme.pdb strand id: C

K,95
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 95
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2095
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2095
pdbx nonpoly scheme.pdb strand id: C

K,96
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 96
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2096
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2096
pdbx nonpoly scheme.pdb strand id: C

K,97
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 97
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2097
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2097
pdbx nonpoly scheme.pdb strand id: C

K,98
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 98
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2098
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2098
pdbx nonpoly scheme.pdb strand id: C

K,99
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 99
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2099
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2099
pdbx nonpoly scheme.pdb strand id: C

K,100
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 100
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2100
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2100
pdbx nonpoly scheme.pdb strand id: C

K,101
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 101
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2101
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2101
pdbx nonpoly scheme.pdb strand id: C

K,102
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 102
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2102
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2102
pdbx nonpoly scheme.pdb strand id: C

K,103
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 103
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2103
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2103
pdbx nonpoly scheme.pdb strand id: C

K,104
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 104
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2104
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2104
pdbx nonpoly scheme.pdb strand id: C

K,105
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 105
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2105
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2105
pdbx nonpoly scheme.pdb strand id: C

K,106
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 106
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2106
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2106
pdbx nonpoly scheme.pdb strand id: C

K,107
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 107
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2107
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2107
pdbx nonpoly scheme.pdb strand id: C

K,108
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 108
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2108
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2108
pdbx nonpoly scheme.pdb strand id: C

K,109
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 109
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2109
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2109
pdbx nonpoly scheme.pdb strand id: C

K,110
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 110
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2110
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2110
pdbx nonpoly scheme.pdb strand id: C

K,111
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 111
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2111
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2111
pdbx nonpoly scheme.pdb strand id: C

K,112
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 112
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2112
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2112
pdbx nonpoly scheme.pdb strand id: C

K,113
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 113
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2113
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2113
pdbx nonpoly scheme.pdb strand id: C

K,114
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 114
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2114
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2114
pdbx nonpoly scheme.pdb strand id: C

K,115
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 115
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2115
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2115
pdbx nonpoly scheme.pdb strand id: C

K,116
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 116
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2116
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2116
pdbx nonpoly scheme.pdb strand id: C

K,117
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 117
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2117
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2117
pdbx nonpoly scheme.pdb strand id: C

K,118
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 118
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2118
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2118
pdbx nonpoly scheme.pdb strand id: C

K,119
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 119
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2119
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2119
pdbx nonpoly scheme.pdb strand id: C

K,120
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 120
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2120
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2120
pdbx nonpoly scheme.pdb strand id: C

K,121
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 121
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2121
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2121
pdbx nonpoly scheme.pdb strand id: C

K,122
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 122
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2122
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2122
pdbx nonpoly scheme.pdb strand id: C

K,123
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: K
pdbx nonpoly scheme.ndb seq num: 123
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2123
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2123
pdbx nonpoly scheme.pdb strand id: C

L,1
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2001
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2001
pdbx nonpoly scheme.pdb strand id: D

L,2
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2002
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2002
pdbx nonpoly scheme.pdb strand id: D

L,3
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2003
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2003
pdbx nonpoly scheme.pdb strand id: D

L,4
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2004
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2004
pdbx nonpoly scheme.pdb strand id: D

L,5
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2005
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2005
pdbx nonpoly scheme.pdb strand id: D

L,6
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2006
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2006
pdbx nonpoly scheme.pdb strand id: D

L,7
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2007
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2007
pdbx nonpoly scheme.pdb strand id: D

L,8
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2008
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2008
pdbx nonpoly scheme.pdb strand id: D

L,9
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2009
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2009
pdbx nonpoly scheme.pdb strand id: D

L,10
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2010
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2010
pdbx nonpoly scheme.pdb strand id: D

L,11
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2011
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2011
pdbx nonpoly scheme.pdb strand id: D

L,12
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2012
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2012
pdbx nonpoly scheme.pdb strand id: D

L,13
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2013
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2013
pdbx nonpoly scheme.pdb strand id: D

L,14
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2014
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2014
pdbx nonpoly scheme.pdb strand id: D

L,15
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2015
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2015
pdbx nonpoly scheme.pdb strand id: D

L,16
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2016
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2016
pdbx nonpoly scheme.pdb strand id: D

L,17
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2017
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2017
pdbx nonpoly scheme.pdb strand id: D

L,18
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2018
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2018
pdbx nonpoly scheme.pdb strand id: D

L,19
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2019
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2019
pdbx nonpoly scheme.pdb strand id: D

L,20
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2020
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2020
pdbx nonpoly scheme.pdb strand id: D

L,21
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2021
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2021
pdbx nonpoly scheme.pdb strand id: D

L,22
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2022
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2022
pdbx nonpoly scheme.pdb strand id: D

L,23
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2023
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2023
pdbx nonpoly scheme.pdb strand id: D

L,24
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2024
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2024
pdbx nonpoly scheme.pdb strand id: D

L,25
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2025
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2025
pdbx nonpoly scheme.pdb strand id: D

L,26
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2026
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2026
pdbx nonpoly scheme.pdb strand id: D

L,27
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2027
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2027
pdbx nonpoly scheme.pdb strand id: D

L,28
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2028
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2028
pdbx nonpoly scheme.pdb strand id: D

L,29
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2029
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2029
pdbx nonpoly scheme.pdb strand id: D

L,30
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2030
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2030
pdbx nonpoly scheme.pdb strand id: D

L,31
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2031
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2031
pdbx nonpoly scheme.pdb strand id: D

L,32
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2032
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2032
pdbx nonpoly scheme.pdb strand id: D

L,33
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2033
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2033
pdbx nonpoly scheme.pdb strand id: D

L,34
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2034
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2034
pdbx nonpoly scheme.pdb strand id: D

L,35
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2035
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2035
pdbx nonpoly scheme.pdb strand id: D

L,36
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2036
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2036
pdbx nonpoly scheme.pdb strand id: D

L,37
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2037
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2037
pdbx nonpoly scheme.pdb strand id: D

L,38
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2038
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2038
pdbx nonpoly scheme.pdb strand id: D

L,39
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2039
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2039
pdbx nonpoly scheme.pdb strand id: D

L,40
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2040
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2040
pdbx nonpoly scheme.pdb strand id: D

L,41
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2041
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2041
pdbx nonpoly scheme.pdb strand id: D

L,42
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2042
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2042
pdbx nonpoly scheme.pdb strand id: D

L,43
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2043
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2043
pdbx nonpoly scheme.pdb strand id: D

L,44
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2044
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2044
pdbx nonpoly scheme.pdb strand id: D

L,45
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2045
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2045
pdbx nonpoly scheme.pdb strand id: D

L,46
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2046
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2046
pdbx nonpoly scheme.pdb strand id: D

L,47
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2047
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2047
pdbx nonpoly scheme.pdb strand id: D

L,48
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2048
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2048
pdbx nonpoly scheme.pdb strand id: D

L,49
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2049
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2049
pdbx nonpoly scheme.pdb strand id: D

L,50
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2050
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2050
pdbx nonpoly scheme.pdb strand id: D

L,51
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2051
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2051
pdbx nonpoly scheme.pdb strand id: D

L,52
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2052
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2052
pdbx nonpoly scheme.pdb strand id: D

L,53
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2053
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2053
pdbx nonpoly scheme.pdb strand id: D

L,54
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2054
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2054
pdbx nonpoly scheme.pdb strand id: D

L,55
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2055
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2055
pdbx nonpoly scheme.pdb strand id: D

L,56
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2056
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2056
pdbx nonpoly scheme.pdb strand id: D

L,57
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 57
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2057
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2057
pdbx nonpoly scheme.pdb strand id: D

L,58
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 58
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2058
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2058
pdbx nonpoly scheme.pdb strand id: D

L,59
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 59
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2059
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2059
pdbx nonpoly scheme.pdb strand id: D

L,60
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 60
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2060
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2060
pdbx nonpoly scheme.pdb strand id: D

L,61
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 61
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2061
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2061
pdbx nonpoly scheme.pdb strand id: D

L,62
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 62
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2062
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2062
pdbx nonpoly scheme.pdb strand id: D

L,63
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 63
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2063
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2063
pdbx nonpoly scheme.pdb strand id: D

L,64
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 64
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2064
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2064
pdbx nonpoly scheme.pdb strand id: D

L,65
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 65
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2065
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2065
pdbx nonpoly scheme.pdb strand id: D

L,66
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 66
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2066
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2066
pdbx nonpoly scheme.pdb strand id: D

L,67
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 67
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2067
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2067
pdbx nonpoly scheme.pdb strand id: D

L,68
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 68
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2068
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2068
pdbx nonpoly scheme.pdb strand id: D

L,69
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 69
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2069
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2069
pdbx nonpoly scheme.pdb strand id: D

L,70
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 70
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2070
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2070
pdbx nonpoly scheme.pdb strand id: D

L,71
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 71
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2071
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2071
pdbx nonpoly scheme.pdb strand id: D

L,72
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 72
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2072
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2072
pdbx nonpoly scheme.pdb strand id: D

L,73
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 73
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2073
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2073
pdbx nonpoly scheme.pdb strand id: D

L,74
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 74
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2074
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2074
pdbx nonpoly scheme.pdb strand id: D

L,75
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 75
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2075
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2075
pdbx nonpoly scheme.pdb strand id: D

L,76
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 76
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2076
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2076
pdbx nonpoly scheme.pdb strand id: D

L,77
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 77
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2077
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2077
pdbx nonpoly scheme.pdb strand id: D

L,78
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 78
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2078
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2078
pdbx nonpoly scheme.pdb strand id: D

L,79
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 79
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2079
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2079
pdbx nonpoly scheme.pdb strand id: D

L,80
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 80
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2080
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2080
pdbx nonpoly scheme.pdb strand id: D

L,81
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 81
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2081
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2081
pdbx nonpoly scheme.pdb strand id: D

L,82
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 82
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2082
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2082
pdbx nonpoly scheme.pdb strand id: D

L,83
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 83
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2083
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2083
pdbx nonpoly scheme.pdb strand id: D

L,84
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 84
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2084
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2084
pdbx nonpoly scheme.pdb strand id: D

L,85
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 85
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2085
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2085
pdbx nonpoly scheme.pdb strand id: D

L,86
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 86
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2086
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2086
pdbx nonpoly scheme.pdb strand id: D

L,87
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 87
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2087
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2087
pdbx nonpoly scheme.pdb strand id: D

L,88
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 88
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2088
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2088
pdbx nonpoly scheme.pdb strand id: D

L,89
type: pdbx nonpoly scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx nonpoly scheme.asym id: L
pdbx nonpoly scheme.ndb seq num: 89
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2089
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 2089
pdbx nonpoly scheme.pdb strand id: D

A,1,GLY,1
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,1
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: -3
pdbx poly seq scheme.pdb strand id: A

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
referenced by pdbx poly seq scheme: A,1,GLY,1
referenced by pdbx poly seq scheme: A,1,PRO,2
referenced by pdbx poly seq scheme: A,1,GLY,3
referenced by pdbx poly seq scheme: A,1,SER,4
referenced by pdbx poly seq scheme: A,1,MET,5
referenced by pdbx poly seq scheme: A,1,GLU,6
referenced by pdbx poly seq scheme: A,1,ASN,7
referenced by pdbx poly seq scheme: A,1,PHE,8
referenced by pdbx poly seq scheme: A,1,GLN,9
referenced by pdbx poly seq scheme: A,1,LYS,10
referenced by pdbx poly seq scheme: A,1,VAL,11
referenced by pdbx poly seq scheme: A,1,GLU,12
referenced by pdbx poly seq scheme: A,1,LYS,13
referenced by pdbx poly seq scheme: A,1,ILE,14
referenced by pdbx poly seq scheme: A,1,GLY,15
referenced by pdbx poly seq scheme: A,1,GLU,16
referenced by pdbx poly seq scheme: A,1,GLY,17
referenced by pdbx poly seq scheme: A,1,THR,18
referenced by pdbx poly seq scheme: A,1,TYR,19
referenced by pdbx poly seq scheme: A,1,GLY,20
referenced by pdbx poly seq scheme: A,1,VAL,21
referenced by pdbx poly seq scheme: A,1,VAL,22
referenced by pdbx poly seq scheme: A,1,TYR,23
referenced by pdbx poly seq scheme: A,1,LYS,24
referenced by pdbx poly seq scheme: A,1,ALA,25
referenced by pdbx poly seq scheme: A,1,ARG,26
referenced by pdbx poly seq scheme: A,1,ASN,27
referenced by pdbx poly seq scheme: A,1,LYS,28
referenced by pdbx poly seq scheme: A,1,LEU,29
referenced by pdbx poly seq scheme: A,1,THR,30
referenced by pdbx poly seq scheme: A,1,GLY,31
referenced by pdbx poly seq scheme: A,1,GLU,32
referenced by pdbx poly seq scheme: A,1,VAL,33
referenced by pdbx poly seq scheme: A,1,VAL,34
referenced by pdbx poly seq scheme: A,1,ALA,35
referenced by pdbx poly seq scheme: A,1,LEU,36
referenced by pdbx poly seq scheme: A,1,LYS,37
referenced by pdbx poly seq scheme: A,1,LYS,38
referenced by pdbx poly seq scheme: A,1,ILE,39
referenced by pdbx poly seq scheme: A,1,ARG,40
referenced by pdbx poly seq scheme: A,1,LEU,41
referenced by pdbx poly seq scheme: A,1,ASP,42
referenced by pdbx poly seq scheme: A,1,THR,43
referenced by pdbx poly seq scheme: A,1,GLU,44
referenced by pdbx poly seq scheme: A,1,THR,45
referenced by pdbx poly seq scheme: A,1,GLU,46
referenced by pdbx poly seq scheme: A,1,GLY,47
referenced by pdbx poly seq scheme: A,1,VAL,48
referenced by pdbx poly seq scheme: A,1,PRO,49
referenced by pdbx poly seq scheme: A,1,SER,50
referenced by pdbx poly seq scheme: A,1,THR,51
referenced by pdbx poly seq scheme: A,1,ALA,52
referenced by pdbx poly seq scheme: A,1,ILE,53
referenced by pdbx poly seq scheme: A,1,ARG,54
referenced by pdbx poly seq scheme: A,1,GLU,55
referenced by pdbx poly seq scheme: A,1,ILE,56
referenced by pdbx poly seq scheme: A,1,SER,57
referenced by pdbx poly seq scheme: A,1,LEU,58
referenced by pdbx poly seq scheme: A,1,LEU,59
referenced by pdbx poly seq scheme: A,1,LYS,60
referenced by pdbx poly seq scheme: A,1,GLU,61
referenced by pdbx poly seq scheme: A,1,LEU,62
referenced by pdbx poly seq scheme: A,1,ASN,63
referenced by pdbx poly seq scheme: A,1,HIS,64
referenced by pdbx poly seq scheme: A,1,PRO,65
referenced by pdbx poly seq scheme: A,1,ASN,66
referenced by pdbx poly seq scheme: A,1,ILE,67
referenced by pdbx poly seq scheme: A,1,VAL,68
referenced by pdbx poly seq scheme: A,1,LYS,69
referenced by pdbx poly seq scheme: A,1,LEU,70
referenced by pdbx poly seq scheme: A,1,LEU,71
referenced by pdbx poly seq scheme: A,1,ASP,72
referenced by pdbx poly seq scheme: A,1,VAL,73
referenced by pdbx poly seq scheme: A,1,ILE,74
referenced by pdbx poly seq scheme: A,1,HIS,75
referenced by pdbx poly seq scheme: A,1,THR,76
referenced by pdbx poly seq scheme: A,1,GLU,77
referenced by pdbx poly seq scheme: A,1,ASN,78
referenced by pdbx poly seq scheme: A,1,LYS,79
referenced by pdbx poly seq scheme: A,1,LEU,80

A,1,PRO,2
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,2
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: -2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: -2
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,3
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,3
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: -1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: -1
pdbx poly seq scheme.pdb strand id: A

A,1,SER,4
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,4
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 0
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 0
pdbx poly seq scheme.pdb strand id: A

A,1,MET,5
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,5
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 1
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,6
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,6
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 2
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,7
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,7
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 3
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 3
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,8
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,8
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 4
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 4
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,9
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,9
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 5
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 5
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,10
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,10
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 6
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 6
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,11
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,11
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 7
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 7
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,12
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,12
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 8
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 8
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,13
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,13
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 9
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 9
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,14
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,14
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 10
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 10
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,15
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,15
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 11
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 11
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,16
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,16
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 12
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 12
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,17
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,17
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 13
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 13
pdbx poly seq scheme.pdb strand id: A

A,1,THR,18
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,18
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 14
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 14
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,19
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,19
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 15
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 15
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,20
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,20
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 16
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 16
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,21
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,21
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 17
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 17
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,22
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,22
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 18
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 18
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,23
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,23
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 19
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 19
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,24
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,24
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 20
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 20
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,25
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,25
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 21
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 21
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,26
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,26
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 22
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 22
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,27
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,27
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 23
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 23
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,28
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,28
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 24
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 24
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,29
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,29
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 25
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 25
pdbx poly seq scheme.pdb strand id: A

A,1,THR,30
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,30
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 26
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 26
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,31
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,31
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 27
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 27
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,32
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,32
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 28
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 28
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,33
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,33
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 29
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 29
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,34
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,34
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 30
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 30
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,35
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,35
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 31
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 31
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,36
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,36
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 32
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 32
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,37
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,37
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 33
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 33
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,38
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,38
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 34
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 34
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,39
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,39
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 35
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 35
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,40
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,40
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 36
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 36
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,41
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,41
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 37
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 37
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,42
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,42
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb seq num: 38
pdbx poly seq scheme.pdb strand id: A

A,1,THR,43
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,43
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb seq num: 39
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,44
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,44
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb seq num: 40
pdbx poly seq scheme.pdb strand id: A

A,1,THR,45
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,45
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 41
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 41
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,46
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,46
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 42
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 42
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,47
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,47
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 43
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 43
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,48
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,48
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 44
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 44
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,49
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,49
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 45
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 45
pdbx poly seq scheme.pdb strand id: A

A,1,SER,50
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,50
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 46
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 46
pdbx poly seq scheme.pdb strand id: A

A,1,THR,51
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,51
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 47
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 47
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,52
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,52
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 48
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 48
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,53
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,53
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 49
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 49
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,54
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,54
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 50
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 50
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,55
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,55
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 51
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 51
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,56
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,56
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 52
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 52
pdbx poly seq scheme.pdb strand id: A

A,1,SER,57
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,57
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 53
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 53
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,58
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,58
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 54
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 54
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,59
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,59
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 55
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 55
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,60
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,60
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 56
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 56
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,61
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,61
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 57
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 57
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,62
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,62
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 58
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 58
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,63
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,63
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 59
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 59
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,64
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,64
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 60
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 60
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,65
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,65
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 61
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 61
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,66
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,66
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 62
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 62
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,67
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,67
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 63
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 63
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,68
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,68
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 64
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 64
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,69
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,69
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 65
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 65
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,70
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,70
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 66
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 66
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,71
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,71
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 67
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 67
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,72
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,72
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 68
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 68
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,73
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,73
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 69
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 69
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,74
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,74
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 70
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 70
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,75
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,75
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 71
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 71
pdbx poly seq scheme.pdb strand id: A

A,1,THR,76
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,76
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 72
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 72
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,77
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,77
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 73
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 73
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,78
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,78
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 74
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 74
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,79
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,79
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 75
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 75
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,80
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,80
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 76
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 76
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,81
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,81
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 77
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 77
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,82
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,82
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 78
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 78
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,83
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,83
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 79
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 79
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,84
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,84
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 80
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 80
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,85
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,85
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 81
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 81
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,86
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,86
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 82
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 82
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,87
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,87
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 83
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 83
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,88
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,88
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 84
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 84
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,89
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,89
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 85
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 85
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,90
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,90
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 86
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 86
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,91
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,91
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 87
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 87
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,92
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,92
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 88
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 88
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,93
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,93
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 89
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 89
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,94
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,94
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 90
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 90
pdbx poly seq scheme.pdb strand id: A

A,1,MET,95
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,95
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 91
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 91
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,96
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,96
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 92
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 92
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,97
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,97
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 93
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 93
pdbx poly seq scheme.pdb strand id: A

A,1,SER,98
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,98
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 94
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 94
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,99
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,99
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 95
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 95
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,100
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,100
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 96
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 96
pdbx poly seq scheme.pdb strand id: A

A,1,THR,101
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,101
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 97
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 97
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,102
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,102
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 98
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 98
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,103
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,103
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 99
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 99
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,104
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,104
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 100
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 100
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,105
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,105
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 101
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 101
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,106
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,106
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 102
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 102
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,107
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,107
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 103
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 103
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,108
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,108
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 104
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 104
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,109
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,109
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 105
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 105
pdbx poly seq scheme.pdb strand id: A

A,1,SER,110
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,110
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 106
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 106
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,111
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,111
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 107
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 107
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,112
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,112
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 108
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 108
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,113
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,113
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 109
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,114
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,114
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 110
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,115
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,115
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 111
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 111
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,116
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,116
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 112
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 112
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,117
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,117
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 113
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 113
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,118
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,118
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 114
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 114
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,119
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,119
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 115
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 115
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,120
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,120
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 116
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 116
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,121
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,121
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 117
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 117
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,122
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,122
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 118
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 118
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,123
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,123
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 119
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 119
pdbx poly seq scheme.pdb strand id: A

A,1,SER,124
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,124
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 120
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 120
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,125
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,125
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 121
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 121
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,126
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,126
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 122
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 122
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,127
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,127
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 123
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 123
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,128
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,128
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 124
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 124
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,129
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,129
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 125
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 125
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,130
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,130
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 126
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 126
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,131
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,131
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 127
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 127
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,132
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,132
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 128
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 128
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,133
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,133
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 129
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 129
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,134
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,134
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 130
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 130
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,135
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,135
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 131
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 131
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,136
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,136
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 132
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 132
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,137
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,137
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 133
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 133
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,138
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,138
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 134
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 134
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,139
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,139
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 135
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 135
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,140
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,140
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 136
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 136
pdbx poly seq scheme.pdb strand id: A

A,1,THR,141
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,141
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 137
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 137
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,142
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,142
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 138
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 138
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,143
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,143
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 139
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 139
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,144
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,144
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 140
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 140
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,145
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,145
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 141
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 141
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,146
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,146
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 142
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 142
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,147
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,147
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 143
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 143
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,148
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,148
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 144
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 144
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,149
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,149
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 145
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 145
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,150
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,150
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 146
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 146
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,151
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,151
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 147
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 147
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,152
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,152
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 148
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 148
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,153
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,153
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 149
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 149
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,154
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,154
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 150
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 150
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,155
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,155
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 151
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 151
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,156
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,156
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 152
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 152
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,157
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,157
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 153
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 153
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,158
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,158
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 154
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 154
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,159
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,159
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 155
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 155
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,160
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,160
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 156
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 156
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,161
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,161
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 157
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 157
pdbx poly seq scheme.pdb strand id: A

A,1,THR,162
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,162
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 158
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 158
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,163
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,163
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 159
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 159
pdbx poly seq scheme.pdb strand id: A

A,1,TPO,164
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TPO,164
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TPO
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: TPO
pdbx poly seq scheme.auth seq num: 160
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: TPO
pdbx poly seq scheme.pdb seq num: 160
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,165
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,165
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 161
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 161
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,166
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,166
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 162
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 162
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,167
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,167
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 163
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 163
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,168
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,168
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 164
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 164
pdbx poly seq scheme.pdb strand id: A

A,1,THR,169
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,169
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 165
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 165
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,170
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,170
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 166
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 166
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,171
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,171
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 167
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 167
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,172
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,172
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 168
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 168
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,173
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,173
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 169
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 169
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,174
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,174
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 170
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 170
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,175
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,175
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 171
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 171
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,176
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,176
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 172
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 172
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,177
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,177
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 173
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 173
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,178
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,178
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 174
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 174
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,179
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,179
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 175
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 175
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,180
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,180
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 176
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 176
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,181
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,181
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 177
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 177
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,182
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,182
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 178
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 178
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,183
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,183
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 179
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 179
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,184
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,184
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 180
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 180
pdbx poly seq scheme.pdb strand id: A

A,1,SER,185
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,185
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 181
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 181
pdbx poly seq scheme.pdb strand id: A

A,1,THR,186
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,186
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 182
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 182
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,187
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,187
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 183
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 183
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,188
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,188
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 184
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,189
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,189
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 185
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,190
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,190
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 186
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,191
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,191
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 187
pdbx poly seq scheme.pdb strand id: A

A,1,SER,192
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,192
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 188
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,193
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,193
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 189
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 189
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,194
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,194
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 190
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 190
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,195
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,195
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 191
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 191
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,196
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,196
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 192
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 192
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,197
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,197
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 193
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 193
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,198
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,198
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 194
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 194
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,199
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,199
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 195
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 195
pdbx poly seq scheme.pdb strand id: A

A,1,MET,200
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,200
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 196
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 196
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,201
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,201
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 197
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 197
pdbx poly seq scheme.pdb strand id: A

A,1,THR,202
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,202
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 198
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 198
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,203
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,203
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 199
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 199
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,204
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,204
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 200
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 200
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,205
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,205
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 201
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 201
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,206
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,206
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 202
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 202
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,207
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,207
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 203
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,208
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,208
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 204
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 204
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,209
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,209
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 205
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 205
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,210
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,210
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 206
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 206
pdbx poly seq scheme.pdb strand id: A

A,1,SER,211
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,211
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 207
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 207
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,212
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,212
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 208
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 208
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,213
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,213
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 209
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 209
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,214
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,214
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 210
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 210
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,215
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,215
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 211
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 211
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,216
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,216
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 212
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 212
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,217
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,217
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 213
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 213
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,218
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,218
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 214
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 214
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,219
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,219
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 215
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 215
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,220
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,220
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 216
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 216
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,221
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,221
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 217
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 217
pdbx poly seq scheme.pdb strand id: A

A,1,THR,222
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,222
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 218
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 218
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,223
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,223
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 219
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 219
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,224
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,224
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 220
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 220
pdbx poly seq scheme.pdb strand id: A

A,1,THR,225
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,225
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 221
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 221
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,226
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,226
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 222
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 222
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,227
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,227
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 223
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 223
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,228
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,228
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 224
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 224
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,229
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,229
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 225
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 225
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,230
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,230
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 226
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 226
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,231
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,231
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 227
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 227
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,232
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,232
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 228
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 228
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,233
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,233
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 229
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 229
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,234
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,234
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 230
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 230
pdbx poly seq scheme.pdb strand id: A

A,1,THR,235
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,235
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 231
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 231
pdbx poly seq scheme.pdb strand id: A

A,1,SER,236
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,236
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 232
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 232
pdbx poly seq scheme.pdb strand id: A

A,1,MET,237
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,237
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 233
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 233
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,238
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,238
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 234
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 234
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,239
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,239
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 235
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 235
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,240
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,240
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 236
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 236
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,241
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,241
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 237
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 237
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,242
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,242
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 238
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 238
pdbx poly seq scheme.pdb strand id: A

A,1,SER,243
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,243
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 239
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 239
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,244
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,244
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 240
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 240
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,245
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,245
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 241
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 241
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,246
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,246
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 242
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 242
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,247
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,247
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 243
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 243
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,248
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,248
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 244
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 244
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,249
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,249
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 245
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 245
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,250
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,250
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 246
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 246
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,251
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,251
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 247
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 247
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,252
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,252
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 248
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 248
pdbx poly seq scheme.pdb strand id: A

A,1,SER,253
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,253
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 249
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 249
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,254
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,254
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 250
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 250
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,255
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,255
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 251
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 251
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,256
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,256
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 252
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 252
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,257
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,257
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 253
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 253
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,258
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,258
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 254
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 254
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,259
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,259
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 255
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 255
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,260
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,260
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 256
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 256
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,261
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,261
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 257
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 257
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,262
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,262
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 258
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 258
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,263
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,263
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 259
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 259
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,264
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,264
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 260
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 260
pdbx poly seq scheme.pdb strand id: A

A,1,SER,265
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,265
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 261
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 261
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,266
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,266
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 262
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 262
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,267
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,267
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 263
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 263
pdbx poly seq scheme.pdb strand id: A

A,1,SER,268
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,268
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 264
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 264
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,269
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,269
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 265
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 265
pdbx poly seq scheme.pdb strand id: A

A,1,MET,270
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,270
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 266
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,271
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,271
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 267
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,272
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,272
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 268
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,273
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,273
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 269
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 269
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,274
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,274
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 270
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 270
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,275
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,275
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 271
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 271
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,276
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,276
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 272
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 272
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,277
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,277
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 273
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 273
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,278
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,278
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 274
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 274
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,279
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,279
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 275
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 275
pdbx poly seq scheme.pdb strand id: A

A,1,SER,280
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,280
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 276
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 276
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,281
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,281
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 277
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 277
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,282
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,282
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 278
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 278
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,283
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,283
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 279
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 279
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,284
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,284
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 280
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 280
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,285
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,285
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 281
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 281
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,286
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,286
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 282
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 282
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,287
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,287
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 283
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 283
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,288
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,288
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 284
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 284
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,289
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,289
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 285
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 285
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,290
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,290
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 286
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 286
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,291
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,291
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 287
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 287
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,292
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,292
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 288
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 288
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,293
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,293
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 289
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 289
pdbx poly seq scheme.pdb strand id: A

A,1,THR,294
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,294
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 290
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 290
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,295
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,295
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 291
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 291
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,296
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,296
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 292
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 292
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,297
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,297
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 293
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 293
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,298
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,298
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 294
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 294
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,299
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,299
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 295
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 295
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,300
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,300
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 296
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 296
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,301
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,301
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 297
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 297
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,302
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,302
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/A
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb seq num: 298
pdbx poly seq scheme.pdb strand id: A

B,2,VAL,1
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,1
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: 175
pdbx poly seq scheme.pdb strand id: B

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
referenced by pdbx poly seq scheme: B,2,VAL,1
referenced by pdbx poly seq scheme: B,2,PRO,2
referenced by pdbx poly seq scheme: B,2,ASP,3
referenced by pdbx poly seq scheme: B,2,TYR,4
referenced by pdbx poly seq scheme: B,2,HIS,5
referenced by pdbx poly seq scheme: B,2,GLU,6
referenced by pdbx poly seq scheme: B,2,ASP,7
referenced by pdbx poly seq scheme: B,2,ILE,8
referenced by pdbx poly seq scheme: B,2,HIS,9
referenced by pdbx poly seq scheme: B,2,THR,10
referenced by pdbx poly seq scheme: B,2,TYR,11
referenced by pdbx poly seq scheme: B,2,LEU,12
referenced by pdbx poly seq scheme: B,2,ARG,13
referenced by pdbx poly seq scheme: B,2,GLU,14
referenced by pdbx poly seq scheme: B,2,MET,15
referenced by pdbx poly seq scheme: B,2,GLU,16
referenced by pdbx poly seq scheme: B,2,VAL,17
referenced by pdbx poly seq scheme: B,2,LYS,18
referenced by pdbx poly seq scheme: B,2,CYS,19
referenced by pdbx poly seq scheme: B,2,LYS,20
referenced by pdbx poly seq scheme: B,2,PRO,21
referenced by pdbx poly seq scheme: B,2,LYS,22
referenced by pdbx poly seq scheme: B,2,VAL,23
referenced by pdbx poly seq scheme: B,2,GLY,24
referenced by pdbx poly seq scheme: B,2,TYR,25
referenced by pdbx poly seq scheme: B,2,MET,26
referenced by pdbx poly seq scheme: B,2,LYS,27
referenced by pdbx poly seq scheme: B,2,LYS,28
referenced by pdbx poly seq scheme: B,2,GLN,29
referenced by pdbx poly seq scheme: B,2,PRO,30
referenced by pdbx poly seq scheme: B,2,ASP,31
referenced by pdbx poly seq scheme: B,2,ILE,32
referenced by pdbx poly seq scheme: B,2,THR,33
referenced by pdbx poly seq scheme: B,2,ASN,34
referenced by pdbx poly seq scheme: B,2,SER,35
referenced by pdbx poly seq scheme: B,2,MET,36
referenced by pdbx poly seq scheme: B,2,ARG,37
referenced by pdbx poly seq scheme: B,2,ALA,38
referenced by pdbx poly seq scheme: B,2,ILE,39
referenced by pdbx poly seq scheme: B,2,LEU,40
referenced by pdbx poly seq scheme: B,2,VAL,41
referenced by pdbx poly seq scheme: B,2,ASP,42
referenced by pdbx poly seq scheme: B,2,TRP,43
referenced by pdbx poly seq scheme: B,2,LEU,44
referenced by pdbx poly seq scheme: B,2,VAL,45
referenced by pdbx poly seq scheme: B,2,GLU,46
referenced by pdbx poly seq scheme: B,2,VAL,47
referenced by pdbx poly seq scheme: B,2,GLY,48
referenced by pdbx poly seq scheme: B,2,GLU,49
referenced by pdbx poly seq scheme: B,2,GLU,50
referenced by pdbx poly seq scheme: B,2,TYR,51
referenced by pdbx poly seq scheme: B,2,LYS,52
referenced by pdbx poly seq scheme: B,2,LEU,53
referenced by pdbx poly seq scheme: B,2,GLN,54
referenced by pdbx poly seq scheme: B,2,ASN,55
referenced by pdbx poly seq scheme: B,2,GLU,56
referenced by pdbx poly seq scheme: B,2,THR,57
referenced by pdbx poly seq scheme: B,2,LEU,58
referenced by pdbx poly seq scheme: B,2,HIS,59
referenced by pdbx poly seq scheme: B,2,LEU,60
referenced by pdbx poly seq scheme: B,2,ALA,61
referenced by pdbx poly seq scheme: B,2,VAL,62
referenced by pdbx poly seq scheme: B,2,ASN,63
referenced by pdbx poly seq scheme: B,2,TYR,64
referenced by pdbx poly seq scheme: B,2,ILE,65
referenced by pdbx poly seq scheme: B,2,ASP,66
referenced by pdbx poly seq scheme: B,2,ARG,67
referenced by pdbx poly seq scheme: B,2,PHE,68
referenced by pdbx poly seq scheme: B,2,LEU,69
referenced by pdbx poly seq scheme: B,2,SER,70
referenced by pdbx poly seq scheme: B,2,SER,71
referenced by pdbx poly seq scheme: B,2,MET,72
referenced by pdbx poly seq scheme: B,2,SER,73
referenced by pdbx poly seq scheme: B,2,VAL,74
referenced by pdbx poly seq scheme: B,2,LEU,75
referenced by pdbx poly seq scheme: B,2,ARG,76
referenced by pdbx poly seq scheme: B,2,GLY,77
referenced by pdbx poly seq scheme: B,2,LYS,78
referenced by pdbx poly seq scheme: B,2,LEU,79
referenced by pdbx poly seq scheme: B,2,GLN,80

B,2,PRO,2
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,2
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb seq num: 176
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,3
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,3
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 177
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 177
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,4
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,4
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 178
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 178
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,5
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,5
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 179
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 179
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,6
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,6
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 180
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 180
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,7
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,7
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 181
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 181
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,8
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,8
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 182
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 182
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,9
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,9
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 183
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 183
pdbx poly seq scheme.pdb strand id: B

B,2,THR,10
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,10
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 184
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,11
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,11
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 185
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,12
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,12
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 186
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,13
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,13
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 187
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,14
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,14
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 188
pdbx poly seq scheme.pdb strand id: B

B,2,MET,15
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,15
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 189
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 189
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,16
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,16
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 190
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 190
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,17
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,17
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 191
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 191
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,18
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,18
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 192
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 192
pdbx poly seq scheme.pdb strand id: B

B,2,CYS,19
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,19
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 193
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 193
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,20
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,20
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 194
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 194
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,21
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,21
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 195
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 195
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,22
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,22
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 196
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 196
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,23
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,23
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 197
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 197
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,24
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,24
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 198
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 198
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,25
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,25
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 199
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 199
pdbx poly seq scheme.pdb strand id: B

B,2,MET,26
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,26
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 200
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 200
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,27
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,27
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 201
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 201
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,28
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,28
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 202
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 202
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,29
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,29
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 203
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,30
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,30
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 204
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 204
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,31
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,31
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 205
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 205
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,32
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,32
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 206
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 206
pdbx poly seq scheme.pdb strand id: B

B,2,THR,33
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,33
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 207
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 207
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,34
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,34
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 208
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 208
pdbx poly seq scheme.pdb strand id: B

B,2,SER,35
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,35
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 209
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 209
pdbx poly seq scheme.pdb strand id: B

B,2,MET,36
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,36
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 210
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 210
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,37
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,37
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 211
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 211
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,38
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,38
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 212
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 212
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,39
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,39
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 213
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 213
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,40
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,40
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 214
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 214
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,41
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,41
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 215
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 215
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,42
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,42
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 216
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 216
pdbx poly seq scheme.pdb strand id: B

B,2,TRP,43
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TRP,43
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 217
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 217
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,44
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,44
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 218
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 218
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,45
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,45
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 219
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 219
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,46
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,46
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 220
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 220
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,47
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,47
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 221
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 221
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,48
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,48
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 222
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 222
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,49
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,49
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 223
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 223
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,50
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,50
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 224
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 224
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,51
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,51
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 225
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 225
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,52
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,52
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 226
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 226
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,53
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,53
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 227
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 227
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,54
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,54
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 228
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 228
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,55
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,55
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 229
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 229
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,56
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,56
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 230
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 230
pdbx poly seq scheme.pdb strand id: B

B,2,THR,57
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,57
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 231
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 231
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,58
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,58
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 232
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 232
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,59
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,59
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 233
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 233
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,60
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,60
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 234
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 234
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,61
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,61
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 235
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 235
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,62
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,62
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 236
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 236
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,63
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,63
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 237
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 237
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,64
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,64
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 238
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 238
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,65
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,65
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 239
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 239
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,66
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,66
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 240
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 240
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,67
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,67
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 241
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 241
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,68
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,68
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 242
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 242
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,69
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,69
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 243
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 243
pdbx poly seq scheme.pdb strand id: B

B,2,SER,70
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,70
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 244
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 244
pdbx poly seq scheme.pdb strand id: B

B,2,SER,71
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,71
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 245
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 245
pdbx poly seq scheme.pdb strand id: B

B,2,MET,72
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,72
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 246
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 246
pdbx poly seq scheme.pdb strand id: B

B,2,SER,73
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,73
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 247
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 247
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,74
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,74
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 248
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 248
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,75
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,75
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 249
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 249
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,76
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,76
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 250
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 250
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,77
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,77
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 251
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 251
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,78
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,78
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 252
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 252
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,79
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,79
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 253
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 253
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,80
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,80
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 254
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 254
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,81
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,81
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 255
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 255
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,82
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,82
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 256
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 256
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,83
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,83
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 257
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 257
pdbx poly seq scheme.pdb strand id: B

B,2,THR,84
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,84
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 258
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 258
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,85
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,85
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 259
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 259
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,86
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,86
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 260
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 260
pdbx poly seq scheme.pdb strand id: B

B,2,MET,87
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,87
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 261
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 261
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,88
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,88
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 262
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 262
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,89
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,89
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 263
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 263
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,90
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,90
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 264
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 264
pdbx poly seq scheme.pdb strand id: B

B,2,SER,91
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,91
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 265
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 265
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,92
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,92
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 266
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,93
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,93
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 267
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,94
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,94
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 268
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,95
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,95
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 269
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 269
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,96
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,96
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 270
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 270
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,97
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,97
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 271
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 271
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,98
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,98
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 272
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 272
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,99
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,99
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 273
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 273
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,100
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,100
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 274
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 274
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,101
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,101
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 275
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 275
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,102
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,102
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 276
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 276
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,103
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,103
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 277
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 277
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,104
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,104
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 278
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 278
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,105
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,105
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 279
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 279
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,106
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,106
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 280
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 280
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,107
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,107
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 281
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 281
pdbx poly seq scheme.pdb strand id: B

B,2,THR,108
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,108
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 282
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 282
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,109
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,109
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb seq num: 283
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,110
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,110
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb seq num: 284
pdbx poly seq scheme.pdb strand id: B

B,2,THR,111
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,111
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 285
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 285
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,112
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,112
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 286
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 286
pdbx poly seq scheme.pdb strand id: B

B,2,THR,113
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,113
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 287
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 287
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,114
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,114
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 288
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 288
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,115
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,115
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 289
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 289
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,116
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,116
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 290
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 290
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,117
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,117
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 291
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 291
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,118
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,118
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 292
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 292
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,119
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,119
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 293
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 293
pdbx poly seq scheme.pdb strand id: B

B,2,MET,120
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,120
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 294
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 294
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,121
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,121
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 295
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 295
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,122
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,122
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 296
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 296
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,123
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,123
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 297
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 297
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,124
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,124
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 298
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 298
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,125
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,125
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 299
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 299
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,126
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,126
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 300
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 300
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,127
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,127
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 301
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 301
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,128
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,128
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 302
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 302
pdbx poly seq scheme.pdb strand id: B

B,2,THR,129
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,129
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 303
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 303
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,130
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,130
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 304
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 304
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,131
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,131
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 305
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 305
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,132
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,132
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 306
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 306
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,133
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,133
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 307
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 307
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,134
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,134
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 308
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 308
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,135
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,135
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 309
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 309
pdbx poly seq scheme.pdb strand id: B

B,2,THR,136
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,136
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 310
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 310
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,137
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,137
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 311
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 311
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,138
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,138
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 312
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 312
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,139
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,139
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 313
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 313
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,140
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,140
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 314
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 314
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,141
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,141
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 315
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 315
pdbx poly seq scheme.pdb strand id: B

B,2,THR,142
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,142
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 316
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 316
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,143
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,143
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 317
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 317
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,144
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,144
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 318
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 318
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,145
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,145
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 319
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 319
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,146
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,146
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 320
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 320
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,147
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,147
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 321
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 321
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,148
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,148
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 322
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 322
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,149
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,149
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 323
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 323
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,150
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,150
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 324
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 324
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,151
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,151
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 325
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,152
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,152
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 326
pdbx poly seq scheme.pdb strand id: B

B,2,CYS,153
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,153
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 327
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,154
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,154
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 328
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,155
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,155
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 329
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,156
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,156
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 330
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 330
pdbx poly seq scheme.pdb strand id: B

B,2,SER,157
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,157
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 331
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 331
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,158
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,158
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 332
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 332
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,159
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,159
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 333
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 333
pdbx poly seq scheme.pdb strand id: B

B,2,MET,160
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,160
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 334
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 334
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,161
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,161
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 335
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 335
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,162
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,162
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 336
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 336
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,163
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,163
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 337
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 337
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,164
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,164
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 338
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 338
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,165
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,165
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 339
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 339
pdbx poly seq scheme.pdb strand id: B

B,2,SER,166
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,166
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 340
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 340
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,167
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,167
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 341
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 341
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,168
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,168
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 342
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 342
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,169
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,169
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 343
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 343
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,170
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,170
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 344
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 344
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,171
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,171
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 345
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 345
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,172
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,172
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 346
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 346
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,173
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,173
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 347
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 347
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,174
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,174
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 348
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 348
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,175
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,175
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 349
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 349
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,176
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,176
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 350
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 350
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,177
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,177
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 351
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 351
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,178
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,178
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 352
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 352
pdbx poly seq scheme.pdb strand id: B

B,2,SER,179
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,179
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 353
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 353
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,180
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,180
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 354
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 354
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,181
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,181
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 355
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 355
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,182
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,182
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 356
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 356
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,183
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,183
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 357
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 357
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,184
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,184
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 358
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 358
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,185
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,185
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 359
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 359
pdbx poly seq scheme.pdb strand id: B

B,2,PHE,186
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,186
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 360
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 360
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,187
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,187
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 361
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 361
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,188
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,188
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 362
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 362
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,189
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,189
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 363
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 363
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,190
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,190
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 364
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 364
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,191
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,191
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 365
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 365
pdbx poly seq scheme.pdb strand id: B

B,2,THR,192
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,192
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 366
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 366
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,193
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,193
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 367
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 367
pdbx poly seq scheme.pdb strand id: B

B,2,THR,194
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,194
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 368
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 368
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,195
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,195
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 369
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 369
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,196
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,196
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 370
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 370
pdbx poly seq scheme.pdb strand id: B

B,2,SER,197
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,197
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 371
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 371
pdbx poly seq scheme.pdb strand id: B

B,2,TRP,198
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TRP,198
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 372
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 372
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,199
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,199
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 373
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 373
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,200
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,200
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 374
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 374
pdbx poly seq scheme.pdb strand id: B

B,2,SER,201
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,201
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 375
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 375
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,202
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,202
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 376
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 376
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,203
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,203
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 377
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 377
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,204
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,204
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 378
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 378
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,205
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,205
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 379
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 379
pdbx poly seq scheme.pdb strand id: B

B,2,THR,206
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,206
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 380
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 380
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,207
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,207
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 381
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 381
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,208
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,208
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 382
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 382
pdbx poly seq scheme.pdb strand id: B

B,2,THR,209
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,209
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 383
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 383
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,210
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,210
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 384
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 384
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,211
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,211
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 385
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 385
pdbx poly seq scheme.pdb strand id: B

B,2,SER,212
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,212
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 386
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 386
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,213
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,213
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 387
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 387
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,214
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,214
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 388
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 388
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,215
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,215
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 389
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 389
pdbx poly seq scheme.pdb strand id: B

B,2,CYS,216
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,216
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 390
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 390
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,217
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,217
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 391
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 391
pdbx poly seq scheme.pdb strand id: B

B,2,MET,218
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,218
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 392
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 392
pdbx poly seq scheme.pdb strand id: B

B,2,ASP,219
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,219
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 393
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 393
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,220
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,220
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 394
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 394
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,221
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,221
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 395
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 395
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,222
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,222
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 396
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 396
pdbx poly seq scheme.pdb strand id: B

B,2,THR,223
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,223
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 397
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 397
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,224
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,224
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 398
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 398
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,225
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,225
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 399
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 399
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,226
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,226
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 400
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 400
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,227
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,227
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 401
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 401
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,228
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,228
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 402
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 402
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,229
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,229
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 403
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 403
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,230
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,230
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 404
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 404
pdbx poly seq scheme.pdb strand id: B

B,2,ALA,231
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,231
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 405
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 405
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,232
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,232
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 406
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 406
pdbx poly seq scheme.pdb strand id: B

B,2,GLN,233
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,233
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 407
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 407
pdbx poly seq scheme.pdb strand id: B

B,2,SER,234
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,234
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 408
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 408
pdbx poly seq scheme.pdb strand id: B

B,2,ILE,235
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,235
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 409
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 409
pdbx poly seq scheme.pdb strand id: B

B,2,ARG,236
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,236
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 410
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 410
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,237
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,237
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 411
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 411
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,238
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,238
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 412
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 412
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,239
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,239
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 413
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 413
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,240
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,240
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 414
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 414
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,241
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,241
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 415
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 415
pdbx poly seq scheme.pdb strand id: B

B,2,SER,242
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,242
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 416
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 416
pdbx poly seq scheme.pdb strand id: B

B,2,LYS,243
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,243
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 417
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 417
pdbx poly seq scheme.pdb strand id: B

B,2,TYR,244
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,244
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 418
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 418
pdbx poly seq scheme.pdb strand id: B

B,2,HIS,245
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,245
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 419
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 419
pdbx poly seq scheme.pdb strand id: B

B,2,GLY,246
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,246
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 420
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 420
pdbx poly seq scheme.pdb strand id: B

B,2,VAL,247
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,247
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 421
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 421
pdbx poly seq scheme.pdb strand id: B

B,2,SER,248
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,248
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 422
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 422
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,249
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,249
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 423
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 423
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,250
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,250
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 424
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 424
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,251
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,251
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 425
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 425
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,252
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,252
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 426
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 426
pdbx poly seq scheme.pdb strand id: B

B,2,PRO,253
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,253
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 427
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 427
pdbx poly seq scheme.pdb strand id: B

B,2,GLU,254
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,254
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 428
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 428
pdbx poly seq scheme.pdb strand id: B

B,2,THR,255
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,255
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 429
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 429
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,256
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,256
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 430
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 430
pdbx poly seq scheme.pdb strand id: B

B,2,ASN,257
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,257
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 431
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 431
pdbx poly seq scheme.pdb strand id: B

B,2,LEU,258
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,258
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/B
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 432
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 432
pdbx poly seq scheme.pdb strand id: B

C,1,GLY,1
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,1
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: -3
pdbx poly seq scheme.pdb strand id: C

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
referenced by pdbx poly seq scheme: C,1,GLY,1
referenced by pdbx poly seq scheme: C,1,PRO,2
referenced by pdbx poly seq scheme: C,1,GLY,3
referenced by pdbx poly seq scheme: C,1,SER,4
referenced by pdbx poly seq scheme: C,1,MET,5
referenced by pdbx poly seq scheme: C,1,GLU,6
referenced by pdbx poly seq scheme: C,1,ASN,7
referenced by pdbx poly seq scheme: C,1,PHE,8
referenced by pdbx poly seq scheme: C,1,GLN,9
referenced by pdbx poly seq scheme: C,1,LYS,10
referenced by pdbx poly seq scheme: C,1,VAL,11
referenced by pdbx poly seq scheme: C,1,GLU,12
referenced by pdbx poly seq scheme: C,1,LYS,13
referenced by pdbx poly seq scheme: C,1,ILE,14
referenced by pdbx poly seq scheme: C,1,GLY,15
referenced by pdbx poly seq scheme: C,1,GLU,16
referenced by pdbx poly seq scheme: C,1,GLY,17
referenced by pdbx poly seq scheme: C,1,THR,18
referenced by pdbx poly seq scheme: C,1,TYR,19
referenced by pdbx poly seq scheme: C,1,GLY,20
referenced by pdbx poly seq scheme: C,1,VAL,21
referenced by pdbx poly seq scheme: C,1,VAL,22
referenced by pdbx poly seq scheme: C,1,TYR,23
referenced by pdbx poly seq scheme: C,1,LYS,24
referenced by pdbx poly seq scheme: C,1,ALA,25
referenced by pdbx poly seq scheme: C,1,ARG,26
referenced by pdbx poly seq scheme: C,1,ASN,27
referenced by pdbx poly seq scheme: C,1,LYS,28
referenced by pdbx poly seq scheme: C,1,LEU,29
referenced by pdbx poly seq scheme: C,1,THR,30
referenced by pdbx poly seq scheme: C,1,GLY,31
referenced by pdbx poly seq scheme: C,1,GLU,32
referenced by pdbx poly seq scheme: C,1,VAL,33
referenced by pdbx poly seq scheme: C,1,VAL,34
referenced by pdbx poly seq scheme: C,1,ALA,35
referenced by pdbx poly seq scheme: C,1,LEU,36
referenced by pdbx poly seq scheme: C,1,LYS,37
referenced by pdbx poly seq scheme: C,1,LYS,38
referenced by pdbx poly seq scheme: C,1,ILE,39
referenced by pdbx poly seq scheme: C,1,ARG,40
referenced by pdbx poly seq scheme: C,1,LEU,41
referenced by pdbx poly seq scheme: C,1,ASP,42
referenced by pdbx poly seq scheme: C,1,THR,43
referenced by pdbx poly seq scheme: C,1,GLU,44
referenced by pdbx poly seq scheme: C,1,THR,45
referenced by pdbx poly seq scheme: C,1,GLU,46
referenced by pdbx poly seq scheme: C,1,GLY,47
referenced by pdbx poly seq scheme: C,1,VAL,48
referenced by pdbx poly seq scheme: C,1,PRO,49
referenced by pdbx poly seq scheme: C,1,SER,50
referenced by pdbx poly seq scheme: C,1,THR,51
referenced by pdbx poly seq scheme: C,1,ALA,52
referenced by pdbx poly seq scheme: C,1,ILE,53
referenced by pdbx poly seq scheme: C,1,ARG,54
referenced by pdbx poly seq scheme: C,1,GLU,55
referenced by pdbx poly seq scheme: C,1,ILE,56
referenced by pdbx poly seq scheme: C,1,SER,57
referenced by pdbx poly seq scheme: C,1,LEU,58
referenced by pdbx poly seq scheme: C,1,LEU,59
referenced by pdbx poly seq scheme: C,1,LYS,60
referenced by pdbx poly seq scheme: C,1,GLU,61
referenced by pdbx poly seq scheme: C,1,LEU,62
referenced by pdbx poly seq scheme: C,1,ASN,63
referenced by pdbx poly seq scheme: C,1,HIS,64
referenced by pdbx poly seq scheme: C,1,PRO,65
referenced by pdbx poly seq scheme: C,1,ASN,66
referenced by pdbx poly seq scheme: C,1,ILE,67
referenced by pdbx poly seq scheme: C,1,VAL,68
referenced by pdbx poly seq scheme: C,1,LYS,69
referenced by pdbx poly seq scheme: C,1,LEU,70
referenced by pdbx poly seq scheme: C,1,LEU,71
referenced by pdbx poly seq scheme: C,1,ASP,72
referenced by pdbx poly seq scheme: C,1,VAL,73
referenced by pdbx poly seq scheme: C,1,ILE,74
referenced by pdbx poly seq scheme: C,1,HIS,75
referenced by pdbx poly seq scheme: C,1,THR,76
referenced by pdbx poly seq scheme: C,1,GLU,77
referenced by pdbx poly seq scheme: C,1,ASN,78
referenced by pdbx poly seq scheme: C,1,LYS,79
referenced by pdbx poly seq scheme: C,1,LEU,80

C,1,PRO,2
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,2
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: -2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: -2
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,3
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,3
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: -1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: -1
pdbx poly seq scheme.pdb strand id: C

C,1,SER,4
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,4
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 0
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 0
pdbx poly seq scheme.pdb strand id: C

C,1,MET,5
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,5
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 1
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,6
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,6
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 2
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,7
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,7
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 3
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 3
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,8
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,8
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 4
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 4
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,9
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,9
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 5
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 5
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,10
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,10
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 6
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 6
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,11
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,11
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 7
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 7
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,12
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,12
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 8
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 8
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,13
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,13
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 9
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 9
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,14
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,14
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 10
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 10
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,15
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,15
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 11
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 11
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,16
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,16
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 12
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 12
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,17
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,17
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 13
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 13
pdbx poly seq scheme.pdb strand id: C

C,1,THR,18
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,18
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 14
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 14
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,19
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,19
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 15
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 15
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,20
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,20
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 16
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 16
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,21
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,21
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 17
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 17
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,22
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,22
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 18
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 18
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,23
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,23
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 19
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 19
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,24
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,24
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 20
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 20
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,25
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,25
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 21
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 21
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,26
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,26
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 22
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 22
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,27
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,27
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 23
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 23
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,28
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,28
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 24
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 24
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,29
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,29
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 25
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 25
pdbx poly seq scheme.pdb strand id: C

C,1,THR,30
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,30
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 26
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 26
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,31
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,31
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 27
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 27
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,32
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,32
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 28
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 28
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,33
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,33
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 29
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 29
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,34
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,34
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 30
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 30
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,35
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,35
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 31
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 31
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,36
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,36
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 32
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 32
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,37
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,37
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 33
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 33
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,38
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,38
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 34
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 34
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,39
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,39
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 35
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 35
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,40
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,40
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 36
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 36
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,41
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,41
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 37
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 37
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,42
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,42
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 38
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 38
pdbx poly seq scheme.pdb strand id: C

C,1,THR,43
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,43
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 39
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 39
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,44
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,44
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 40
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 40
pdbx poly seq scheme.pdb strand id: C

C,1,THR,45
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,45
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 41
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 41
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,46
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,46
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 42
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 42
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,47
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,47
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 43
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 43
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,48
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,48
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 44
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 44
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,49
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,49
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 45
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 45
pdbx poly seq scheme.pdb strand id: C

C,1,SER,50
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,50
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 46
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 46
pdbx poly seq scheme.pdb strand id: C

C,1,THR,51
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,51
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 47
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 47
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,52
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,52
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 48
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 48
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,53
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,53
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 49
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 49
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,54
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,54
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 50
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 50
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,55
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,55
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 51
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 51
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,56
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,56
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 52
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 52
pdbx poly seq scheme.pdb strand id: C

C,1,SER,57
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,57
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 53
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 53
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,58
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,58
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 54
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 54
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,59
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,59
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 55
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 55
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,60
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,60
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 56
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 56
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,61
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,61
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 57
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 57
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,62
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,62
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 58
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 58
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,63
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,63
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 59
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 59
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,64
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,64
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 60
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 60
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,65
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,65
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 61
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 61
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,66
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,66
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 62
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 62
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,67
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,67
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 63
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 63
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,68
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,68
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 64
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 64
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,69
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,69
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 65
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 65
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,70
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,70
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 66
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 66
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,71
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,71
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 67
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 67
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,72
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,72
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 68
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 68
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,73
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,73
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 69
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 69
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,74
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,74
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 70
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 70
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,75
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,75
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 71
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 71
pdbx poly seq scheme.pdb strand id: C

C,1,THR,76
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,76
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 72
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 72
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,77
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,77
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 73
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 73
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,78
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,78
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 74
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 74
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,79
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,79
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 75
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 75
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,80
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,80
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 76
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 76
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,81
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,81
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 77
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 77
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,82
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,82
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 78
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 78
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,83
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,83
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 79
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 79
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,84
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,84
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 80
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 80
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,85
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,85
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 81
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 81
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,86
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,86
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 82
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 82
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,87
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,87
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 83
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 83
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,88
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,88
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 84
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 84
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,89
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,89
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 85
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 85
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,90
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,90
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 86
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 86
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,91
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,91
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 87
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 87
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,92
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,92
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 88
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 88
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,93
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,93
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 89
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 89
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,94
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,94
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 90
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 90
pdbx poly seq scheme.pdb strand id: C

C,1,MET,95
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,95
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 91
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 91
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,96
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,96
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 92
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 92
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,97
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,97
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 93
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 93
pdbx poly seq scheme.pdb strand id: C

C,1,SER,98
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,98
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 94
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 94
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,99
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,99
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 95
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 95
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,100
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,100
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 96
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 96
pdbx poly seq scheme.pdb strand id: C

C,1,THR,101
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,101
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 97
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 97
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,102
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,102
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 98
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 98
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,103
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,103
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 99
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 99
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,104
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,104
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 100
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 100
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,105
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,105
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 101
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 101
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,106
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,106
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 102
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 102
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,107
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,107
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 103
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 103
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,108
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,108
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 104
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 104
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,109
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,109
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 105
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 105
pdbx poly seq scheme.pdb strand id: C

C,1,SER,110
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,110
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 106
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 106
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,111
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,111
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 107
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 107
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,112
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,112
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 108
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 108
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,113
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,113
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 109
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,114
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,114
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 110
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,115
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,115
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 111
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 111
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,116
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,116
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 112
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 112
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,117
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,117
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 113
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 113
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,118
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,118
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 114
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 114
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,119
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,119
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 115
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 115
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,120
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,120
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 116
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 116
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,121
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,121
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 117
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 117
pdbx poly seq scheme.pdb strand id: C

C,1,CYS,122
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,122
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 118
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 118
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,123
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,123
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 119
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 119
pdbx poly seq scheme.pdb strand id: C

C,1,SER,124
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,124
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 120
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 120
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,125
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,125
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 121
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 121
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,126
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,126
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 122
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 122
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,127
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,127
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 123
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 123
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,128
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,128
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 124
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 124
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,129
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,129
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 125
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 125
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,130
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,130
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 126
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 126
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,131
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,131
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 127
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 127
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,132
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,132
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 128
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 128
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,133
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,133
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 129
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 129
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,134
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,134
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 130
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 130
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,135
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,135
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 131
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 131
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,136
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,136
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 132
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 132
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,137
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,137
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 133
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 133
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,138
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,138
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 134
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 134
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,139
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,139
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 135
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 135
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,140
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,140
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 136
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 136
pdbx poly seq scheme.pdb strand id: C

C,1,THR,141
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,141
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 137
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 137
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,142
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,142
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 138
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 138
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,143
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,143
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 139
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 139
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,144
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,144
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 140
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 140
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,145
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,145
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 141
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 141
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,146
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,146
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 142
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 142
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,147
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,147
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 143
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 143
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,148
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,148
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 144
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 144
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,149
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,149
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 145
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 145
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,150
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,150
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 146
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 146
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,151
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,151
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 147
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 147
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,152
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,152
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 148
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 148
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,153
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,153
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 149
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 149
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,154
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,154
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 150
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 150
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,155
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,155
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 151
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 151
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,156
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,156
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 152
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 152
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,157
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,157
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 153
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 153
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,158
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,158
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 154
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 154
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,159
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,159
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 155
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 155
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,160
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,160
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 156
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 156
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,161
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,161
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 157
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 157
pdbx poly seq scheme.pdb strand id: C

C,1,THR,162
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,162
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 158
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 158
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,163
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,163
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 159
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 159
pdbx poly seq scheme.pdb strand id: C

C,1,TPO,164
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TPO,164
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TPO
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: TPO
pdbx poly seq scheme.auth seq num: 160
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: TPO
pdbx poly seq scheme.pdb seq num: 160
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,165
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,165
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 161
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 161
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,166
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,166
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 162
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 162
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,167
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,167
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 163
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 163
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,168
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,168
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 164
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 164
pdbx poly seq scheme.pdb strand id: C

C,1,THR,169
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,169
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 165
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 165
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,170
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,170
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 166
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 166
pdbx poly seq scheme.pdb strand id: C

C,1,TRP,171
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,171
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 167
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 167
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,172
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,172
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 168
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 168
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,173
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,173
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 169
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 169
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,174
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,174
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 170
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 170
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,175
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,175
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 171
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 171
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,176
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,176
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 172
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 172
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,177
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,177
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 173
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 173
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,178
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,178
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 174
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 174
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,179
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,179
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 175
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 175
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,180
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,180
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 176
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 176
pdbx poly seq scheme.pdb strand id: C

C,1,CYS,181
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,181
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 177
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 177
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,182
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,182
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 178
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 178
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,183
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,183
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 179
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 179
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,184
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,184
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 180
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 180
pdbx poly seq scheme.pdb strand id: C

C,1,SER,185
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,185
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 181
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 181
pdbx poly seq scheme.pdb strand id: C

C,1,THR,186
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,186
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 182
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 182
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,187
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,187
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 183
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 183
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,188
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,188
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 184
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,189
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,189
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 185
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,190
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,190
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 186
pdbx poly seq scheme.pdb strand id: C

C,1,TRP,191
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,191
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 187
pdbx poly seq scheme.pdb strand id: C

C,1,SER,192
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,192
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 188
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,193
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,193
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 189
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 189
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,194
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,194
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 190
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 190
pdbx poly seq scheme.pdb strand id: C

C,1,CYS,195
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,CYS,195
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 191
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 191
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,196
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,196
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 192
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 192
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,197
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,197
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 193
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 193
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,198
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,198
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 194
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 194
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,199
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,199
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 195
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 195
pdbx poly seq scheme.pdb strand id: C

C,1,MET,200
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,200
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 196
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 196
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,201
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,201
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 197
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 197
pdbx poly seq scheme.pdb strand id: C

C,1,THR,202
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,202
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 198
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 198
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,203
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,203
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 199
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 199
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,204
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,204
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 200
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 200
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,205
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,205
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 201
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 201
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,206
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,206
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 202
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 202
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,207
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,207
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 203
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,208
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,208
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 204
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 204
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,209
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,209
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 205
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 205
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,210
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,210
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 206
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 206
pdbx poly seq scheme.pdb strand id: C

C,1,SER,211
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,211
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 207
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 207
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,212
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,212
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 208
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 208
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,213
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,213
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 209
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 209
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,214
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,214
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 210
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 210
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,215
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,215
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 211
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 211
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,216
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,216
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 212
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 212
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,217
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,217
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 213
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 213
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,218
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,218
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 214
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 214
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,219
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,219
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 215
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 215
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,220
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,220
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 216
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 216
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,221
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,221
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 217
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 217
pdbx poly seq scheme.pdb strand id: C

C,1,THR,222
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,222
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 218
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 218
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,223
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,223
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 219
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 219
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,224
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,224
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 220
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 220
pdbx poly seq scheme.pdb strand id: C

C,1,THR,225
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,225
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 221
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 221
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,226
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,226
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 222
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 222
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,227
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,227
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 223
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 223
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,228
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,228
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 224
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 224
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,229
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,229
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 225
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 225
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,230
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,230
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 226
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 226
pdbx poly seq scheme.pdb strand id: C

C,1,TRP,231
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,231
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 227
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 227
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,232
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,232
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 228
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 228
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,233
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,233
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 229
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 229
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,234
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,234
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 230
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 230
pdbx poly seq scheme.pdb strand id: C

C,1,THR,235
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,235
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 231
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 231
pdbx poly seq scheme.pdb strand id: C

C,1,SER,236
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,236
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 232
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 232
pdbx poly seq scheme.pdb strand id: C

C,1,MET,237
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,237
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 233
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 233
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,238
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,238
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 234
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 234
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,239
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,239
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 235
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 235
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,240
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,240
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 236
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 236
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,241
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,241
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 237
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 237
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,242
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,242
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 238
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 238
pdbx poly seq scheme.pdb strand id: C

C,1,SER,243
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,243
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 239
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 239
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,244
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,244
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 240
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 240
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,245
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,245
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 241
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 241
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,246
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,246
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 242
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 242
pdbx poly seq scheme.pdb strand id: C

C,1,TRP,247
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TRP,247
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 243
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 243
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,248
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,248
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 244
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 244
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,249
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,249
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 245
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 245
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,250
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,250
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 246
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 246
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,251
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,251
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 247
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 247
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,252
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,252
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 248
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 248
pdbx poly seq scheme.pdb strand id: C

C,1,SER,253
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,253
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 249
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 249
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,254
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,254
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 250
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 250
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,255
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,255
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 251
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 251
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,256
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,256
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 252
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 252
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,257
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,257
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 253
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 253
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,258
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,258
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 254
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 254
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,259
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,259
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 255
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 255
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,260
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,260
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 256
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 256
pdbx poly seq scheme.pdb strand id: C

C,1,GLU,261
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLU,261
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 257
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 257
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,262
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,262
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 258
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 258
pdbx poly seq scheme.pdb strand id: C

C,1,GLY,263
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLY,263
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 259
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 259
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,264
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,264
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 260
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 260
pdbx poly seq scheme.pdb strand id: C

C,1,SER,265
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,265
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 261
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 261
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,266
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,266
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 262
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 262
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,267
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,267
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 263
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 263
pdbx poly seq scheme.pdb strand id: C

C,1,SER,268
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,268
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 264
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 264
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,269
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,269
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 265
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 265
pdbx poly seq scheme.pdb strand id: C

C,1,MET,270
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,MET,270
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 266
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,271
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,271
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 267
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,272
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,272
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 268
pdbx poly seq scheme.pdb strand id: C

C,1,TYR,273
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,TYR,273
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 269
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 269
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,274
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,274
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 270
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 270
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,275
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,275
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 271
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 271
pdbx poly seq scheme.pdb strand id: C

C,1,ASN,276
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASN,276
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 272
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 272
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,277
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,277
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 273
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 273
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,278
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,278
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 274
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 274
pdbx poly seq scheme.pdb strand id: C

C,1,ILE,279
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ILE,279
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 275
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 275
pdbx poly seq scheme.pdb strand id: C

C,1,SER,280
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,SER,280
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 276
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 276
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,281
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,281
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 277
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 277
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,282
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,282
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 278
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 278
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,283
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,283
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 279
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 279
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,284
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,284
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 280
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 280
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,285
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,285
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 281
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 281
pdbx poly seq scheme.pdb strand id: C

C,1,ALA,286
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ALA,286
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 282
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 282
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,287
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,287
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 283
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 283
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,288
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,288
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 284
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 284
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,289
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,289
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 285
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 285
pdbx poly seq scheme.pdb strand id: C

C,1,PHE,290
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PHE,290
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 286
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 286
pdbx poly seq scheme.pdb strand id: C

C,1,GLN,291
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,GLN,291
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 287
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 287
pdbx poly seq scheme.pdb strand id: C

C,1,ASP,292
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ASP,292
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 288
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 288
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,293
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,293
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 289
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 289
pdbx poly seq scheme.pdb strand id: C

C,1,THR,294
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,THR,294
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 290
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 290
pdbx poly seq scheme.pdb strand id: C

C,1,LYS,295
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LYS,295
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 291
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 291
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,296
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,296
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 292
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 292
pdbx poly seq scheme.pdb strand id: C

C,1,VAL,297
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,VAL,297
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 293
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 293
pdbx poly seq scheme.pdb strand id: C

C,1,PRO,298
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,PRO,298
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 294
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 294
pdbx poly seq scheme.pdb strand id: C

C,1,HIS,299
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,HIS,299
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb seq num: 295
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,300
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,300
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb seq num: 296
pdbx poly seq scheme.pdb strand id: C

C,1,ARG,301
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,ARG,301
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb seq num: 297
pdbx poly seq scheme.pdb strand id: C

C,1,LEU,302
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 1,LEU,302
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/C
pdbx poly seq scheme.asym id: C
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb seq num: 298
pdbx poly seq scheme.pdb strand id: C

D,2,VAL,1
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,1
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: 175
pdbx poly seq scheme.pdb strand id: D

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
referenced by pdbx poly seq scheme: D,2,VAL,1
referenced by pdbx poly seq scheme: D,2,PRO,2
referenced by pdbx poly seq scheme: D,2,ASP,3
referenced by pdbx poly seq scheme: D,2,TYR,4
referenced by pdbx poly seq scheme: D,2,HIS,5
referenced by pdbx poly seq scheme: D,2,GLU,6
referenced by pdbx poly seq scheme: D,2,ASP,7
referenced by pdbx poly seq scheme: D,2,ILE,8
referenced by pdbx poly seq scheme: D,2,HIS,9
referenced by pdbx poly seq scheme: D,2,THR,10
referenced by pdbx poly seq scheme: D,2,TYR,11
referenced by pdbx poly seq scheme: D,2,LEU,12
referenced by pdbx poly seq scheme: D,2,ARG,13
referenced by pdbx poly seq scheme: D,2,GLU,14
referenced by pdbx poly seq scheme: D,2,MET,15
referenced by pdbx poly seq scheme: D,2,GLU,16
referenced by pdbx poly seq scheme: D,2,VAL,17
referenced by pdbx poly seq scheme: D,2,LYS,18
referenced by pdbx poly seq scheme: D,2,CYS,19
referenced by pdbx poly seq scheme: D,2,LYS,20
referenced by pdbx poly seq scheme: D,2,PRO,21
referenced by pdbx poly seq scheme: D,2,LYS,22
referenced by pdbx poly seq scheme: D,2,VAL,23
referenced by pdbx poly seq scheme: D,2,GLY,24
referenced by pdbx poly seq scheme: D,2,TYR,25
referenced by pdbx poly seq scheme: D,2,MET,26
referenced by pdbx poly seq scheme: D,2,LYS,27
referenced by pdbx poly seq scheme: D,2,LYS,28
referenced by pdbx poly seq scheme: D,2,GLN,29
referenced by pdbx poly seq scheme: D,2,PRO,30
referenced by pdbx poly seq scheme: D,2,ASP,31
referenced by pdbx poly seq scheme: D,2,ILE,32
referenced by pdbx poly seq scheme: D,2,THR,33
referenced by pdbx poly seq scheme: D,2,ASN,34
referenced by pdbx poly seq scheme: D,2,SER,35
referenced by pdbx poly seq scheme: D,2,MET,36
referenced by pdbx poly seq scheme: D,2,ARG,37
referenced by pdbx poly seq scheme: D,2,ALA,38
referenced by pdbx poly seq scheme: D,2,ILE,39
referenced by pdbx poly seq scheme: D,2,LEU,40
referenced by pdbx poly seq scheme: D,2,VAL,41
referenced by pdbx poly seq scheme: D,2,ASP,42
referenced by pdbx poly seq scheme: D,2,TRP,43
referenced by pdbx poly seq scheme: D,2,LEU,44
referenced by pdbx poly seq scheme: D,2,VAL,45
referenced by pdbx poly seq scheme: D,2,GLU,46
referenced by pdbx poly seq scheme: D,2,VAL,47
referenced by pdbx poly seq scheme: D,2,GLY,48
referenced by pdbx poly seq scheme: D,2,GLU,49
referenced by pdbx poly seq scheme: D,2,GLU,50
referenced by pdbx poly seq scheme: D,2,TYR,51
referenced by pdbx poly seq scheme: D,2,LYS,52
referenced by pdbx poly seq scheme: D,2,LEU,53
referenced by pdbx poly seq scheme: D,2,GLN,54
referenced by pdbx poly seq scheme: D,2,ASN,55
referenced by pdbx poly seq scheme: D,2,GLU,56
referenced by pdbx poly seq scheme: D,2,THR,57
referenced by pdbx poly seq scheme: D,2,LEU,58
referenced by pdbx poly seq scheme: D,2,HIS,59
referenced by pdbx poly seq scheme: D,2,LEU,60
referenced by pdbx poly seq scheme: D,2,ALA,61
referenced by pdbx poly seq scheme: D,2,VAL,62
referenced by pdbx poly seq scheme: D,2,ASN,63
referenced by pdbx poly seq scheme: D,2,TYR,64
referenced by pdbx poly seq scheme: D,2,ILE,65
referenced by pdbx poly seq scheme: D,2,ASP,66
referenced by pdbx poly seq scheme: D,2,ARG,67
referenced by pdbx poly seq scheme: D,2,PHE,68
referenced by pdbx poly seq scheme: D,2,LEU,69
referenced by pdbx poly seq scheme: D,2,SER,70
referenced by pdbx poly seq scheme: D,2,SER,71
referenced by pdbx poly seq scheme: D,2,MET,72
referenced by pdbx poly seq scheme: D,2,SER,73
referenced by pdbx poly seq scheme: D,2,VAL,74
referenced by pdbx poly seq scheme: D,2,LEU,75
referenced by pdbx poly seq scheme: D,2,ARG,76
referenced by pdbx poly seq scheme: D,2,GLY,77
referenced by pdbx poly seq scheme: D,2,LYS,78
referenced by pdbx poly seq scheme: D,2,LEU,79
referenced by pdbx poly seq scheme: D,2,GLN,80

D,2,PRO,2
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,2
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 176
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 176
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,3
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,3
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 177
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 177
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,4
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,4
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 178
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 178
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,5
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,5
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 179
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 179
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,6
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,6
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 180
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 180
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,7
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,7
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 181
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 181
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,8
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,8
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 182
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 182
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,9
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,9
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 183
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 183
pdbx poly seq scheme.pdb strand id: D

D,2,THR,10
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,10
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 184
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 184
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,11
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,11
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 185
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 185
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,12
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,12
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 186
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 186
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,13
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,13
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 187
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 187
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,14
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,14
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 188
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 188
pdbx poly seq scheme.pdb strand id: D

D,2,MET,15
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,15
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 189
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 189
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,16
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,16
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 190
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 190
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,17
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,17
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 191
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 191
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,18
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,18
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 192
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 192
pdbx poly seq scheme.pdb strand id: D

D,2,CYS,19
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,19
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 193
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 193
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,20
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,20
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 194
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 194
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,21
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,21
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 195
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 195
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,22
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,22
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 196
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 196
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,23
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,23
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 197
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 197
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,24
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,24
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 198
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 198
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,25
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,25
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 199
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 199
pdbx poly seq scheme.pdb strand id: D

D,2,MET,26
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,26
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 200
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 200
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,27
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,27
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 201
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 201
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,28
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,28
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 202
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 202
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,29
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,29
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 203
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 203
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,30
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,30
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 204
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 204
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,31
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,31
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 205
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 205
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,32
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,32
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 206
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 206
pdbx poly seq scheme.pdb strand id: D

D,2,THR,33
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,33
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 207
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 207
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,34
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,34
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 208
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 208
pdbx poly seq scheme.pdb strand id: D

D,2,SER,35
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,35
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 209
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 209
pdbx poly seq scheme.pdb strand id: D

D,2,MET,36
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,36
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 210
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 210
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,37
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,37
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 211
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 211
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,38
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,38
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 212
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 212
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,39
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,39
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 213
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 213
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,40
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,40
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 214
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 214
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,41
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,41
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 215
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 215
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,42
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,42
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 216
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 216
pdbx poly seq scheme.pdb strand id: D

D,2,TRP,43
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TRP,43
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 217
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 217
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,44
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,44
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 218
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 218
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,45
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,45
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 219
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 219
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,46
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,46
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 220
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 220
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,47
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,47
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 221
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 221
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,48
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,48
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 222
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 222
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,49
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,49
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 223
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 223
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,50
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,50
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 224
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 224
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,51
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,51
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 225
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 225
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,52
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,52
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 226
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 226
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,53
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,53
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 227
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 227
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,54
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,54
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 228
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 228
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,55
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,55
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 229
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 229
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,56
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,56
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 230
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 230
pdbx poly seq scheme.pdb strand id: D

D,2,THR,57
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,57
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 231
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 231
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,58
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,58
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 232
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 232
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,59
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,59
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 233
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 233
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,60
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,60
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 234
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 234
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,61
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,61
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 235
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 235
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,62
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,62
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 236
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 236
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,63
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,63
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 237
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 237
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,64
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,64
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 238
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 238
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,65
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,65
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 239
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 239
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,66
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,66
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 240
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 240
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,67
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,67
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 241
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 241
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,68
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,68
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 242
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 242
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,69
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,69
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 243
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 243
pdbx poly seq scheme.pdb strand id: D

D,2,SER,70
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,70
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 244
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 244
pdbx poly seq scheme.pdb strand id: D

D,2,SER,71
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,71
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 245
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 245
pdbx poly seq scheme.pdb strand id: D

D,2,MET,72
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,72
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 246
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 246
pdbx poly seq scheme.pdb strand id: D

D,2,SER,73
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,73
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 247
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 247
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,74
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,74
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 248
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 248
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,75
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,75
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 249
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 249
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,76
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,76
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 250
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 250
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,77
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,77
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 251
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 251
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,78
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,78
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 252
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 252
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,79
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,79
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 253
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 253
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,80
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,80
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 254
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 254
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,81
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,81
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 255
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 255
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,82
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,82
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 256
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 256
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,83
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,83
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 257
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 257
pdbx poly seq scheme.pdb strand id: D

D,2,THR,84
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,84
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 258
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 258
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,85
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,85
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 259
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 259
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,86
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,86
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 260
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 260
pdbx poly seq scheme.pdb strand id: D

D,2,MET,87
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,87
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 261
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 261
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,88
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,88
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 262
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 262
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,89
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,89
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 263
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 263
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,90
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,90
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 264
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 264
pdbx poly seq scheme.pdb strand id: D

D,2,SER,91
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,91
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 265
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 265
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,92
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,92
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 266
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 266
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,93
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,93
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 267
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 267
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,94
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,94
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 268
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 268
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,95
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,95
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 269
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 269
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,96
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,96
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 270
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 270
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,97
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,97
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 271
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 271
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,98
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,98
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 272
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 272
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,99
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,99
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 273
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 273
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,100
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,100
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 274
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 274
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,101
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,101
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 275
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 275
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,102
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,102
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 276
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 276
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,103
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,103
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 277
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 277
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,104
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,104
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 278
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 278
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,105
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,105
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 279
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 279
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,106
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,106
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 280
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 280
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,107
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,107
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 281
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 281
pdbx poly seq scheme.pdb strand id: D

D,2,THR,108
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,108
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 282
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 282
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,109
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,109
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb seq num: 283
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,110
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,110
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb seq num: 284
pdbx poly seq scheme.pdb strand id: D

D,2,THR,111
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,111
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 285
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 285
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,112
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,112
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 286
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 286
pdbx poly seq scheme.pdb strand id: D

D,2,THR,113
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,113
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 287
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 287
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,114
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,114
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 288
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 288
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,115
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,115
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 289
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 289
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,116
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,116
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 290
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 290
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,117
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,117
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 291
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 291
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,118
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,118
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 292
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 292
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,119
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,119
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 293
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 293
pdbx poly seq scheme.pdb strand id: D

D,2,MET,120
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,120
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 294
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 294
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,121
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,121
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 295
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 295
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,122
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,122
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 296
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 296
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,123
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,123
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 297
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 297
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,124
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,124
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 298
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 298
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,125
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,125
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 299
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 299
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,126
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,126
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 300
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 300
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,127
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,127
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 301
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 301
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,128
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,128
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 302
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 302
pdbx poly seq scheme.pdb strand id: D

D,2,THR,129
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,129
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 303
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 303
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,130
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,130
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 304
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 304
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,131
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,131
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 305
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 305
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,132
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,132
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 306
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 306
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,133
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,133
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 307
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 307
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,134
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,134
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 308
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 308
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,135
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,135
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 309
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 309
pdbx poly seq scheme.pdb strand id: D

D,2,THR,136
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,136
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 310
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 310
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,137
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,137
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 311
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 311
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,138
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,138
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 312
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 312
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,139
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,139
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 313
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 313
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,140
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,140
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 314
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 314
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,141
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,141
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 315
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 315
pdbx poly seq scheme.pdb strand id: D

D,2,THR,142
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,142
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 316
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 316
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,143
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,143
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 317
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 317
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,144
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,144
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 318
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 318
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,145
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,145
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 319
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 319
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,146
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,146
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 320
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 320
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,147
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,147
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 321
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 321
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,148
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,148
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 322
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 322
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,149
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,149
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 323
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 323
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,150
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,150
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 324
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 324
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,151
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,151
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 325
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,152
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,152
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 326
pdbx poly seq scheme.pdb strand id: D

D,2,CYS,153
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,153
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 327
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,154
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,154
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 328
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,155
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,155
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 329
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,156
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,156
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 330
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 330
pdbx poly seq scheme.pdb strand id: D

D,2,SER,157
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,157
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 331
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 331
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,158
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,158
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 332
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 332
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,159
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,159
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 333
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 333
pdbx poly seq scheme.pdb strand id: D

D,2,MET,160
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,160
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 334
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 334
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,161
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,161
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 335
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 335
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,162
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,162
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 336
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 336
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,163
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,163
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 337
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 337
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,164
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,164
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 338
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 338
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,165
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,165
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 339
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 339
pdbx poly seq scheme.pdb strand id: D

D,2,SER,166
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,166
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 340
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 340
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,167
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,167
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 341
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 341
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,168
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,168
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 342
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 342
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,169
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,169
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 343
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 343
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,170
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,170
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 344
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 344
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,171
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,171
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 345
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 345
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,172
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,172
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 346
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 346
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,173
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,173
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 347
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 347
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,174
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,174
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 348
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 348
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,175
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,175
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 349
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 349
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,176
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,176
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 350
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 350
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,177
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,177
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 351
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 351
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,178
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,178
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 352
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 352
pdbx poly seq scheme.pdb strand id: D

D,2,SER,179
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,179
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 353
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 353
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,180
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,180
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 354
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 354
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,181
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,181
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 355
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 355
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,182
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,182
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 356
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 356
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,183
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,183
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 357
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 357
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,184
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,184
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 358
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 358
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,185
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,185
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 359
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 359
pdbx poly seq scheme.pdb strand id: D

D,2,PHE,186
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PHE,186
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 360
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 360
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,187
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,187
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 361
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 361
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,188
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,188
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 362
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 362
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,189
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,189
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 363
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 363
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,190
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,190
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 364
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 364
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,191
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,191
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 365
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 365
pdbx poly seq scheme.pdb strand id: D

D,2,THR,192
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,192
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 366
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 366
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,193
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,193
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 367
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 367
pdbx poly seq scheme.pdb strand id: D

D,2,THR,194
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,194
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 368
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 368
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,195
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,195
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 369
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 369
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,196
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,196
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 370
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 370
pdbx poly seq scheme.pdb strand id: D

D,2,SER,197
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,197
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 371
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 371
pdbx poly seq scheme.pdb strand id: D

D,2,TRP,198
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TRP,198
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 372
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 372
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,199
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,199
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 373
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 373
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,200
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,200
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 374
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 374
pdbx poly seq scheme.pdb strand id: D

D,2,SER,201
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,201
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 375
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 375
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,202
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,202
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 376
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 376
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,203
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,203
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 377
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 377
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,204
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,204
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 378
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 378
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,205
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,205
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 379
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 379
pdbx poly seq scheme.pdb strand id: D

D,2,THR,206
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,206
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 380
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 380
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,207
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,207
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 381
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 381
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,208
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,208
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 382
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 382
pdbx poly seq scheme.pdb strand id: D

D,2,THR,209
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,209
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 383
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 383
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,210
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,210
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 384
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 384
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,211
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,211
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 385
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 385
pdbx poly seq scheme.pdb strand id: D

D,2,SER,212
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,212
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 386
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 386
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,213
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,213
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 387
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 387
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,214
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,214
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 388
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 388
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,215
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,215
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 389
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 389
pdbx poly seq scheme.pdb strand id: D

D,2,CYS,216
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,CYS,216
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 390
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 390
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,217
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,217
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 391
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 391
pdbx poly seq scheme.pdb strand id: D

D,2,MET,218
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,MET,218
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 392
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 392
pdbx poly seq scheme.pdb strand id: D

D,2,ASP,219
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASP,219
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 393
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 393
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,220
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,220
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 394
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 394
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,221
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,221
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 395
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 395
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,222
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,222
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 396
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 396
pdbx poly seq scheme.pdb strand id: D

D,2,THR,223
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,223
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 397
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 397
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,224
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,224
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 398
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 398
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,225
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,225
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 399
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 399
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,226
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,226
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 400
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 400
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,227
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,227
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 401
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 401
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,228
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,228
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 402
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 402
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,229
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,229
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 403
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 403
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,230
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,230
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 404
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 404
pdbx poly seq scheme.pdb strand id: D

D,2,ALA,231
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ALA,231
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 405
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 405
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,232
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,232
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 406
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 406
pdbx poly seq scheme.pdb strand id: D

D,2,GLN,233
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLN,233
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 407
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 407
pdbx poly seq scheme.pdb strand id: D

D,2,SER,234
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,234
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 408
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 408
pdbx poly seq scheme.pdb strand id: D

D,2,ILE,235
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ILE,235
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 409
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 409
pdbx poly seq scheme.pdb strand id: D

D,2,ARG,236
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ARG,236
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 410
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 410
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,237
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,237
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 411
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 411
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,238
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,238
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 412
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 412
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,239
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,239
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 413
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 413
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,240
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,240
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 414
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 414
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,241
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,241
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 415
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 415
pdbx poly seq scheme.pdb strand id: D

D,2,SER,242
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,242
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 416
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 416
pdbx poly seq scheme.pdb strand id: D

D,2,LYS,243
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LYS,243
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 417
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 417
pdbx poly seq scheme.pdb strand id: D

D,2,TYR,244
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,TYR,244
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 418
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 418
pdbx poly seq scheme.pdb strand id: D

D,2,HIS,245
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,HIS,245
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 419
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 419
pdbx poly seq scheme.pdb strand id: D

D,2,GLY,246
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLY,246
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 420
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 420
pdbx poly seq scheme.pdb strand id: D

D,2,VAL,247
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,VAL,247
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 421
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 421
pdbx poly seq scheme.pdb strand id: D

D,2,SER,248
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,SER,248
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 422
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 422
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,249
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,249
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 423
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 423
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,250
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,250
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 424
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 424
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,251
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,251
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 425
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 425
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,252
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,252
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 426
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 426
pdbx poly seq scheme.pdb strand id: D

D,2,PRO,253
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,PRO,253
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 427
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 427
pdbx poly seq scheme.pdb strand id: D

D,2,GLU,254
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,GLU,254
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 428
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 428
pdbx poly seq scheme.pdb strand id: D

D,2,THR,255
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,THR,255
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 429
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 429
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,256
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,256
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 430
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 430
pdbx poly seq scheme.pdb strand id: D

D,2,ASN,257
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,ASN,257
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 431
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 431
pdbx poly seq scheme.pdb strand id: D

D,2,LEU,258
type: pdbx poly seq scheme
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity poly seq: 2,LEU,258
reference to struct asym: http://rdf.wwpdb.org/pdb/4CFN/struct_asym/D
pdbx poly seq scheme.asym id: D
pdbx poly seq scheme.entity id: 2
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 432
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 432
pdbx poly seq scheme.pdb strand id: D

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/1
type: pdbx refine tls
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx refine tls.id: 1
pdbx refine tls.l11: 1.6099
pdbx refine tls.l12: 0.4361
pdbx refine tls.l13: -0.7919
pdbx refine tls.l22: 1.3072
pdbx refine tls.l23: -0.1941
pdbx refine tls.l33: 1.5527
pdbx refine tls.s11: -0.0157
pdbx refine tls.s12: 0.1593
pdbx refine tls.s13: -0.0079
pdbx refine tls.s21: -0.251
pdbx refine tls.s22: 0.0617
pdbx refine tls.s23: 0.0782
pdbx refine tls.s31: -0.0831
pdbx refine tls.s32: -0.1474
pdbx refine tls.s33: -0.046
pdbx refine tls.t11: 0.0792
pdbx refine tls.t12: 0.0047
pdbx refine tls.t13: -0.0185
pdbx refine tls.t22: 0.2018
pdbx refine tls.t23: -0.0057
pdbx refine tls.t33: 0.0096
pdbx refine tls.method: refined
pdbx refine tls.origin x: 6.104
pdbx refine tls.origin y: 40.869
pdbx refine tls.origin z: 63.725
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/1

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/2
type: pdbx refine tls
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx refine tls.id: 2
pdbx refine tls.l11: 1.1173
pdbx refine tls.l12: -0.2474
pdbx refine tls.l13: 0.374
pdbx refine tls.l22: 2.3316
pdbx refine tls.l23: -0.4302
pdbx refine tls.l33: 1.8009
pdbx refine tls.s11: -0.0891
pdbx refine tls.s12: -0.0751
pdbx refine tls.s13: 0.0711
pdbx refine tls.s21: 0.0859
pdbx refine tls.s22: 0.0985
pdbx refine tls.s23: -0.1272
pdbx refine tls.s31: -0.2459
pdbx refine tls.s32: -0.0118
pdbx refine tls.s33: -0.0094
pdbx refine tls.t11: 0.1066
pdbx refine tls.t12: -0.0108
pdbx refine tls.t13: 0.0155
pdbx refine tls.t22: 0.1871
pdbx refine tls.t23: -0.036
pdbx refine tls.t33: 0.019
pdbx refine tls.method: refined
pdbx refine tls.origin x: 21.228
pdbx refine tls.origin y: 67.629
pdbx refine tls.origin z: 76.572
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/2

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/3
type: pdbx refine tls
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx refine tls.id: 3
pdbx refine tls.l11: 1.8928
pdbx refine tls.l12: -0.3213
pdbx refine tls.l13: 0.5088
pdbx refine tls.l22: 1.5717
pdbx refine tls.l23: -0.1318
pdbx refine tls.l33: 0.8854
pdbx refine tls.s11: 0.0987
pdbx refine tls.s12: 0.0258
pdbx refine tls.s13: -0.0971
pdbx refine tls.s21: -0.1055
pdbx refine tls.s22: -0.1066
pdbx refine tls.s23: -0.2675
pdbx refine tls.s31: 0.0609
pdbx refine tls.s32: 0.1033
pdbx refine tls.s33: 0.0079
pdbx refine tls.t11: 0.269
pdbx refine tls.t12: 0.0274
pdbx refine tls.t13: 0.0029
pdbx refine tls.t22: 0.2928
pdbx refine tls.t23: 0.0743
pdbx refine tls.t33: 0.0707
pdbx refine tls.method: refined
pdbx refine tls.origin x: 10.453
pdbx refine tls.origin y: -11.993
pdbx refine tls.origin z: 107.103
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/3

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/4
type: pdbx refine tls
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx refine tls.id: 4
pdbx refine tls.l11: 2.942
pdbx refine tls.l12: -0.1571
pdbx refine tls.l13: -0.4778
pdbx refine tls.l22: 2.5204
pdbx refine tls.l23: -0.1786
pdbx refine tls.l33: 1.4075
pdbx refine tls.s11: 0.0531
pdbx refine tls.s12: -0.0001
pdbx refine tls.s13: 0.3695
pdbx refine tls.s21: -0.1663
pdbx refine tls.s22: -0.1062
pdbx refine tls.s23: -0.4732
pdbx refine tls.s31: -0.1651
pdbx refine tls.s32: 0.3409
pdbx refine tls.s33: 0.0531
pdbx refine tls.t11: 0.2754
pdbx refine tls.t12: -0.0647
pdbx refine tls.t13: -0.0071
pdbx refine tls.t22: 0.2801
pdbx refine tls.t23: 0.0587
pdbx refine tls.t33: 0.1387
pdbx refine tls.method: refined
pdbx refine tls.origin x: 7.473
pdbx refine tls.origin y: 20.832
pdbx refine tls.origin z: 107.909
pdbx refine tls.pdbx refine id: X-RAY DIFFRACTION
referenced by pdbx refine tls group: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/4

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/1
type: pdbx refine tls group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/1
pdbx refine tls group.id: 1
pdbx refine tls group.beg auth asym id: A
pdbx refine tls group.beg auth seq id: -2
pdbx refine tls group.end auth asym id: A
pdbx refine tls group.end auth seq id: 297
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 1

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/2
type: pdbx refine tls group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/2
pdbx refine tls group.id: 2
pdbx refine tls group.beg auth asym id: B
pdbx refine tls group.beg auth seq id: 177
pdbx refine tls group.end auth asym id: B
pdbx refine tls group.end auth seq id: 432
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 2

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/3
type: pdbx refine tls group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/3
pdbx refine tls group.id: 3
pdbx refine tls group.beg auth asym id: C
pdbx refine tls group.beg auth seq id: -2
pdbx refine tls group.end auth asym id: C
pdbx refine tls group.end auth seq id: 294
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 3

http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls_group/4
type: pdbx refine tls group
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx refine tls: http://rdf.wwpdb.org/pdb/4CFN/pdbx_refine_tls/4
pdbx refine tls group.id: 4
pdbx refine tls group.beg auth asym id: D
pdbx refine tls group.beg auth seq id: 176
pdbx refine tls group.end auth asym id: D
pdbx refine tls group.end auth seq id: 432
pdbx refine tls group.pdbx refine id: X-RAY DIFFRACTION
pdbx refine tls group.refine tls id: 4

http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_assembly/1
type: pdbx struct assembly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly.id: 1
pdbx struct assembly.details: software_defined_assembly
pdbx struct assembly.method details: PISA
pdbx struct assembly.oligomeric count: 2
pdbx struct assembly.oligomeric details: dimeric
referenced by pdbx struct assembly gen: 1,C,D,G,H,K,L,1

http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_assembly/2
type: pdbx struct assembly
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly.id: 2
pdbx struct assembly.details: software_defined_assembly
pdbx struct assembly.method details: PISA
pdbx struct assembly.oligomeric count: 2
pdbx struct assembly.oligomeric details: dimeric
referenced by pdbx struct assembly gen: 2,A,B,E,F,I,J,1

1,C,D,G,H,K,L,1
type: pdbx struct assembly gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_assembly/1
pdbx struct assembly gen.assembly id: 1
pdbx struct assembly gen.asym id list: C,D,G,H,K,L
pdbx struct assembly gen.oper expression: 1

2,A,B,E,F,I,J,1
type: pdbx struct assembly gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to pdbx struct assembly: http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_assembly/2
pdbx struct assembly gen.assembly id: 2
pdbx struct assembly gen.asym id list: A,B,E,F,I,J
pdbx struct assembly gen.oper expression: 1

1,ABSA (A^2)
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 1
pdbx struct assembly prop.type: ABSA (A^2)
pdbx struct assembly prop.value: 3460

1,MORE
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 1
pdbx struct assembly prop.type: MORE
pdbx struct assembly prop.value: -19.3

1,SSA (A^2)
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 1
pdbx struct assembly prop.type: SSA (A^2)
pdbx struct assembly prop.value: 23220

2,ABSA (A^2)
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 2
pdbx struct assembly prop.type: ABSA (A^2)
pdbx struct assembly prop.value: 3310

2,MORE
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 2
pdbx struct assembly prop.type: MORE
pdbx struct assembly prop.value: -15.3

2,SSA (A^2)
type: pdbx struct assembly prop
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct assembly prop.biol id: 2
pdbx struct assembly prop.type: SSA (A^2)
pdbx struct assembly prop.value: 23210

http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_mod_residue/1
type: pdbx struct mod residue
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct mod residue.id: 1
pdbx struct mod residue.auth asym id: A
pdbx struct mod residue.auth comp id: TPO
pdbx struct mod residue.auth seq id: 160
pdbx struct mod residue.details: PHOSPHOTHREONINE
pdbx struct mod residue.label asym id: A
pdbx struct mod residue.label comp id: TPO
pdbx struct mod residue.label seq id: 164
pdbx struct mod residue.parent comp id: THR

http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_mod_residue/2
type: pdbx struct mod residue
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct mod residue.id: 2
pdbx struct mod residue.auth asym id: C
pdbx struct mod residue.auth comp id: TPO
pdbx struct mod residue.auth seq id: 160
pdbx struct mod residue.details: PHOSPHOTHREONINE
pdbx struct mod residue.label asym id: C
pdbx struct mod residue.label comp id: TPO
pdbx struct mod residue.label seq id: 164
pdbx struct mod residue.parent comp id: THR

http://rdf.wwpdb.org/pdb/4CFN/pdbx_struct_oper_list/1
type: pdbx struct oper list
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx struct oper list.id: 1
pdbx struct oper list.matrix11: 1
pdbx struct oper list.matrix12: 0
pdbx struct oper list.matrix13: 0
pdbx struct oper list.matrix21: 0
pdbx struct oper list.matrix22: 1
pdbx struct oper list.matrix23: 0
pdbx struct oper list.matrix31: 0
pdbx struct oper list.matrix32: 0
pdbx struct oper list.matrix33: 1
pdbx struct oper list.name: 1_555
pdbx struct oper list.symmetry operation: x,y,z
pdbx struct oper list.type: identity operation
pdbx struct oper list.vector1: 0
pdbx struct oper list.vector2: 0
pdbx struct oper list.vector3: 0

1,2,AA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AA
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ILE
pdbx struct sheet hbond.range 1 auth seq id: 10
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ILE
pdbx struct sheet hbond.range 1 label seq id: 14
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: VAL
pdbx struct sheet hbond.range 2 auth seq id: 18
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: VAL
pdbx struct sheet hbond.range 2 label seq id: 22

AA
referenced by pdbx struct sheet hbond: 1,2,AA
referenced by pdbx struct sheet hbond: 2,3,AA
referenced by pdbx struct sheet hbond: 3,4,AA
referenced by pdbx struct sheet hbond: 4,5,AA
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: AA
struct sheet.number strands: 5
referenced by struct sheet order: 4,5,AA
referenced by struct sheet range: 5,AA
referenced by struct sheet order: 1,2,AA
referenced by struct sheet order: 2,3,AA
referenced by struct sheet order: 3,4,AA
referenced by struct sheet range: 1,AA
referenced by struct sheet range: 2,AA
referenced by struct sheet range: 3,AA
referenced by struct sheet range: 4,AA

2,3,AA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: AA
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ALA
pdbx struct sheet hbond.range 1 auth seq id: 21
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ALA
pdbx struct sheet hbond.range 1 label seq id: 25
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: VAL
pdbx struct sheet hbond.range 2 auth seq id: 30
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: VAL
pdbx struct sheet hbond.range 2 label seq id: 34

3,4,AA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
pdbx struct sheet hbond.range id 1: 3
pdbx struct sheet hbond.range id 2: 4
pdbx struct sheet hbond.sheet id: AA
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ILE
pdbx struct sheet hbond.range 1 auth seq id: 35
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ILE
pdbx struct sheet hbond.range 1 label seq id: 39
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 76
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 80

4,5,AA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
pdbx struct sheet hbond.range id 1: 4
pdbx struct sheet hbond.range id 2: 5
pdbx struct sheet hbond.sheet id: AA
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: VAL
pdbx struct sheet hbond.range 1 auth seq id: 79
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: VAL
pdbx struct sheet hbond.range 1 label seq id: 83
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 67
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 71

1,2,AB
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AB
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: GLN
pdbx struct sheet hbond.range 1 auth seq id: 85
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: GLN
pdbx struct sheet hbond.range 1 label seq id: 89
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ILE
pdbx struct sheet hbond.range 2 auth seq id: 135
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ILE
pdbx struct sheet hbond.range 2 label seq id: 139

AB
referenced by pdbx struct sheet hbond: 1,2,AB
referenced by pdbx struct sheet hbond: 2,3,AB
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: AB
struct sheet.number strands: 3
referenced by struct sheet order: 2,3,AB
referenced by struct sheet range: 3,AB
referenced by struct sheet order: 1,2,AB
referenced by struct sheet range: 1,AB
referenced by struct sheet range: 2,AB

2,3,AB
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: AB
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LEU
pdbx struct sheet hbond.range 1 auth seq id: 134
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LEU
pdbx struct sheet hbond.range 1 label seq id: 138
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LYS
pdbx struct sheet hbond.range 2 auth seq id: 142
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LYS
pdbx struct sheet hbond.range 2 label seq id: 146

1,2,AC
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AC
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: AC
pdbx struct sheet hbond.range 1 auth asym id: A
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LEU
pdbx struct sheet hbond.range 1 auth seq id: 124
pdbx struct sheet hbond.range 1 label asym id: A
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LEU
pdbx struct sheet hbond.range 1 label seq id: 128
pdbx struct sheet hbond.range 2 auth asym id: A
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ARG
pdbx struct sheet hbond.range 2 auth seq id: 150
pdbx struct sheet hbond.range 2 label asym id: A
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ARG
pdbx struct sheet hbond.range 2 label seq id: 154

AC
referenced by pdbx struct sheet hbond: 1,2,AC
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: AC
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,AC
referenced by struct sheet range: 2,AC
referenced by struct sheet range: 1,AC

1,2,CA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: CA
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ILE
pdbx struct sheet hbond.range 1 auth seq id: 10
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ILE
pdbx struct sheet hbond.range 1 label seq id: 14
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: VAL
pdbx struct sheet hbond.range 2 auth seq id: 18
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: VAL
pdbx struct sheet hbond.range 2 label seq id: 22

CA
referenced by pdbx struct sheet hbond: 1,2,CA
referenced by pdbx struct sheet hbond: 2,3,CA
referenced by pdbx struct sheet hbond: 3,4,CA
referenced by pdbx struct sheet hbond: 4,5,CA
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: CA
struct sheet.number strands: 5
referenced by struct sheet order: 4,5,CA
referenced by struct sheet range: 5,CA
referenced by struct sheet order: 1,2,CA
referenced by struct sheet order: 2,3,CA
referenced by struct sheet order: 3,4,CA
referenced by struct sheet range: 1,CA
referenced by struct sheet range: 2,CA
referenced by struct sheet range: 3,CA
referenced by struct sheet range: 4,CA

2,3,CA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: CA
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ALA
pdbx struct sheet hbond.range 1 auth seq id: 21
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ALA
pdbx struct sheet hbond.range 1 label seq id: 25
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: VAL
pdbx struct sheet hbond.range 2 auth seq id: 30
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: VAL
pdbx struct sheet hbond.range 2 label seq id: 34

3,4,CA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
pdbx struct sheet hbond.range id 1: 3
pdbx struct sheet hbond.range id 2: 4
pdbx struct sheet hbond.sheet id: CA
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: ILE
pdbx struct sheet hbond.range 1 auth seq id: 35
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: ILE
pdbx struct sheet hbond.range 1 label seq id: 39
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 76
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 80

4,5,CA
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
pdbx struct sheet hbond.range id 1: 4
pdbx struct sheet hbond.range id 2: 5
pdbx struct sheet hbond.sheet id: CA
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: O
pdbx struct sheet hbond.range 1 auth comp id: VAL
pdbx struct sheet hbond.range 1 auth seq id: 79
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: O
pdbx struct sheet hbond.range 1 label comp id: VAL
pdbx struct sheet hbond.range 1 label seq id: 83
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: N
pdbx struct sheet hbond.range 2 auth comp id: LEU
pdbx struct sheet hbond.range 2 auth seq id: 67
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: N
pdbx struct sheet hbond.range 2 label comp id: LEU
pdbx struct sheet hbond.range 2 label seq id: 71

1,2,CB
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: CB
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: GLN
pdbx struct sheet hbond.range 1 auth seq id: 85
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: GLN
pdbx struct sheet hbond.range 1 label seq id: 89
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ILE
pdbx struct sheet hbond.range 2 auth seq id: 135
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ILE
pdbx struct sheet hbond.range 2 label seq id: 139

CB
referenced by pdbx struct sheet hbond: 1,2,CB
referenced by pdbx struct sheet hbond: 2,3,CB
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: CB
struct sheet.number strands: 3
referenced by struct sheet order: 2,3,CB
referenced by struct sheet range: 3,CB
referenced by struct sheet order: 1,2,CB
referenced by struct sheet range: 1,CB
referenced by struct sheet range: 2,CB

2,3,CB
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
pdbx struct sheet hbond.range id 1: 2
pdbx struct sheet hbond.range id 2: 3
pdbx struct sheet hbond.sheet id: CB
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LEU
pdbx struct sheet hbond.range 1 auth seq id: 134
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LEU
pdbx struct sheet hbond.range 1 label seq id: 138
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: LYS
pdbx struct sheet hbond.range 2 auth seq id: 142
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: LYS
pdbx struct sheet hbond.range 2 label seq id: 146

1,2,CC
type: pdbx struct sheet hbond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CC
pdbx struct sheet hbond.range id 1: 1
pdbx struct sheet hbond.range id 2: 2
pdbx struct sheet hbond.sheet id: CC
pdbx struct sheet hbond.range 1 auth asym id: C
pdbx struct sheet hbond.range 1 auth atom id: N
pdbx struct sheet hbond.range 1 auth comp id: LEU
pdbx struct sheet hbond.range 1 auth seq id: 124
pdbx struct sheet hbond.range 1 label asym id: C
pdbx struct sheet hbond.range 1 label atom id: N
pdbx struct sheet hbond.range 1 label comp id: LEU
pdbx struct sheet hbond.range 1 label seq id: 128
pdbx struct sheet hbond.range 2 auth asym id: C
pdbx struct sheet hbond.range 2 auth atom id: O
pdbx struct sheet hbond.range 2 auth comp id: ARG
pdbx struct sheet hbond.range 2 auth seq id: 150
pdbx struct sheet hbond.range 2 label asym id: C
pdbx struct sheet hbond.range 2 label atom id: O
pdbx struct sheet hbond.range 2 label comp id: ARG
pdbx struct sheet hbond.range 2 label seq id: 154

CC
referenced by pdbx struct sheet hbond: 1,2,CC
type: struct sheet
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct sheet.id: CC
struct sheet.number strands: 2
referenced by struct sheet order: 1,2,CC
referenced by struct sheet range: 2,CC
referenced by struct sheet range: 1,CC

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/1
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 1
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: -3
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/2
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 2
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 38
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 42
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/3
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 3
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 39
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 43
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/4
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 4
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 40
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 44
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/5
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 5
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 298
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 302
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/6
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 6
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 175
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/7
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: PRO
pdbx unobs or zero occ residues.id: 7
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: PRO
pdbx unobs or zero occ residues.auth seq id: 176
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: PRO
pdbx unobs or zero occ residues.label seq id: 2
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/8
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 8
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 283
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 109
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/9
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 9
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 284
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 110
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/10
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 10
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: C
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: -3
pdbx unobs or zero occ residues.label asym id: C
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/11
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: HIS
pdbx unobs or zero occ residues.id: 11
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: C
pdbx unobs or zero occ residues.auth comp id: HIS
pdbx unobs or zero occ residues.auth seq id: 295
pdbx unobs or zero occ residues.label asym id: C
pdbx unobs or zero occ residues.label comp id: HIS
pdbx unobs or zero occ residues.label seq id: 299
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/12
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 12
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: C
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 296
pdbx unobs or zero occ residues.label asym id: C
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 300
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/13
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ARG
pdbx unobs or zero occ residues.id: 13
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: C
pdbx unobs or zero occ residues.auth comp id: ARG
pdbx unobs or zero occ residues.auth seq id: 297
pdbx unobs or zero occ residues.label asym id: C
pdbx unobs or zero occ residues.label comp id: ARG
pdbx unobs or zero occ residues.label seq id: 301
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/14
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: LEU
pdbx unobs or zero occ residues.id: 14
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: C
pdbx unobs or zero occ residues.auth comp id: LEU
pdbx unobs or zero occ residues.auth seq id: 298
pdbx unobs or zero occ residues.label asym id: C
pdbx unobs or zero occ residues.label comp id: LEU
pdbx unobs or zero occ residues.label seq id: 302
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/15
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 15
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: D
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 175
pdbx unobs or zero occ residues.label asym id: D
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/16
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 16
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: D
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 283
pdbx unobs or zero occ residues.label asym id: D
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 109
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_unobs_or_zero_occ_residues/17
type: pdbx unobs or zero occ residues
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 17
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: D
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 284
pdbx unobs or zero occ residues.label asym id: D
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 110
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_chiral/1
type: pdbx validate chiral
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate chiral.id: 1
pdbx validate chiral.pdb model num: 1
pdbx validate chiral.auth asym id: D
pdbx validate chiral.auth atom id: C2
pdbx validate chiral.auth comp id: DTT
pdbx validate chiral.auth seq id: 1433
pdbx validate chiral.details: PLANAR

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/1
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 1
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2045
pdbx validate close contact.dist: 0.61
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/2
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 2
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: CE1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2044
pdbx validate close contact.dist: 0.92
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/3
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 3
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: C
pdbx validate close contact.auth asym id 2: C
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: GLN
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 131
pdbx validate close contact.auth seq id 2: 2069
pdbx validate close contact.dist: 1.32
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/4
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 4
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: CE1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2045
pdbx validate close contact.dist: 1.48
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/5
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 5
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: CAQ
pdbx validate close contact.auth comp id 1: GLN
pdbx validate close contact.auth comp id 2: JYM
pdbx validate close contact.auth seq id 1: 131
pdbx validate close contact.auth seq id 2: 1298
pdbx validate close contact.dist: 1.72
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/6
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 6
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: ND1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2044
pdbx validate close contact.dist: 1.76
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/7
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 7
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: CAR
pdbx validate close contact.auth comp id 1: GLN
pdbx validate close contact.auth comp id 2: JYM
pdbx validate close contact.auth seq id 1: 131
pdbx validate close contact.auth seq id 2: 1298
pdbx validate close contact.dist: 1.9
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/8
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 8
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: CD2
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2045
pdbx validate close contact.dist: 1.93
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/9
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 9
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: C
pdbx validate close contact.auth asym id 2: C
pdbx validate close contact.auth atom id 1: N
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 41
pdbx validate close contact.auth seq id 2: 2025
pdbx validate close contact.dist: 1.96

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/10
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 10
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: C
pdbx validate close contact.auth asym id 2: C
pdbx validate close contact.auth atom id 1: CB
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 72
pdbx validate close contact.auth seq id 2: 2047
pdbx validate close contact.dist: 2

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/11
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 11
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: D
pdbx validate close contact.auth asym id 2: D
pdbx validate close contact.auth atom id 1: N
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 285
pdbx validate close contact.auth seq id 2: 2053
pdbx validate close contact.dist: 2.05

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/12
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 12
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: B
pdbx validate close contact.auth asym id 2: B
pdbx validate close contact.auth atom id 1: OG1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 285
pdbx validate close contact.auth seq id 2: 2077
pdbx validate close contact.dist: 2.06

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/13
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 13
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: C
pdbx validate close contact.auth asym id 2: C
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HOH
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 2025
pdbx validate close contact.auth seq id 2: 2026
pdbx validate close contact.dist: 2.06

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/14
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 14
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: D
pdbx validate close contact.auth asym id 2: D
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: GLN
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 322
pdbx validate close contact.auth seq id 2: 2063
pdbx validate close contact.dist: 2.11

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/15
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 15
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: D
pdbx validate close contact.auth asym id 2: D
pdbx validate close contact.auth atom id 1: OG1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 285
pdbx validate close contact.auth seq id 2: 2052
pdbx validate close contact.dist: 2.14

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/16
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 16
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: B
pdbx validate close contact.auth asym id 2: B
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: GLN
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 317
pdbx validate close contact.auth seq id 2: 2005
pdbx validate close contact.dist: 2.14

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/17
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 17
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: B
pdbx validate close contact.auth asym id 2: B
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: THR
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 285
pdbx validate close contact.auth seq id 2: 2076
pdbx validate close contact.dist: 2.15

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/18
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 18
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: D
pdbx validate close contact.auth asym id 2: D
pdbx validate close contact.auth atom id 1: OG
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: SER
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 209
pdbx validate close contact.auth seq id 2: 2022
pdbx validate close contact.dist: 2.16

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/19
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 19
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: NE2
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 84
pdbx validate close contact.auth seq id 2: 2044
pdbx validate close contact.dist: 2.17
pdbx validate close contact.label alt id 1: B

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/20
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 20
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: B
pdbx validate close contact.auth asym id 2: B
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HOH
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 2073
pdbx validate close contact.auth seq id 2: 2077
pdbx validate close contact.dist: 2.19

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/21
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 21
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: ND1
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HIS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 268
pdbx validate close contact.auth seq id 2: 2169
pdbx validate close contact.dist: 2.19

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/22
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 22
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: A
pdbx validate close contact.auth asym id 2: A
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HOH
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 2044
pdbx validate close contact.auth seq id 2: 2045
pdbx validate close contact.dist: 2.19

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/23
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 23
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: D
pdbx validate close contact.auth asym id 2: D
pdbx validate close contact.auth atom id 1: NZ
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: LYS
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 194
pdbx validate close contact.auth seq id 2: 2007
pdbx validate close contact.dist: 2.19

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_close_contact/24
type: pdbx validate close contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate close contact.id: 24
pdbx validate close contact.pdb model num: 1
pdbx validate close contact.auth asym id 1: B
pdbx validate close contact.auth asym id 2: B
pdbx validate close contact.auth atom id 1: O
pdbx validate close contact.auth atom id 2: O
pdbx validate close contact.auth comp id 1: HOH
pdbx validate close contact.auth comp id 2: HOH
pdbx validate close contact.auth seq id 1: 2142
pdbx validate close contact.auth seq id 2: 2143
pdbx validate close contact.dist: 2.19

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_peptide_omega/1
type: pdbx validate peptide omega
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate peptide omega.id: 1
pdbx validate peptide omega.pdb model num: 1
pdbx validate peptide omega.auth asym id 1: A
pdbx validate peptide omega.auth asym id 2: A
pdbx validate peptide omega.auth comp id 1: THR
pdbx validate peptide omega.auth comp id 2: GLY
pdbx validate peptide omega.auth seq id 1: 97
pdbx validate peptide omega.auth seq id 2: 98
pdbx validate peptide omega.omega: -147.44

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_peptide_omega/2
type: pdbx validate peptide omega
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate peptide omega.id: 2
pdbx validate peptide omega.pdb model num: 1
pdbx validate peptide omega.auth asym id 1: A
pdbx validate peptide omega.auth asym id 2: A
pdbx validate peptide omega.auth comp id 1: PRO
pdbx validate peptide omega.auth comp id 2: HIS
pdbx validate peptide omega.auth seq id 1: 294
pdbx validate peptide omega.auth seq id 2: 295
pdbx validate peptide omega.omega: -136.23

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_peptide_omega/3
type: pdbx validate peptide omega
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate peptide omega.id: 3
pdbx validate peptide omega.pdb model num: 1
pdbx validate peptide omega.auth asym id 1: A
pdbx validate peptide omega.auth asym id 2: A
pdbx validate peptide omega.auth comp id 1: HIS
pdbx validate peptide omega.auth comp id 2: LEU
pdbx validate peptide omega.auth seq id 1: 295
pdbx validate peptide omega.auth seq id 2: 296
pdbx validate peptide omega.omega: -43.72

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_peptide_omega/4
type: pdbx validate peptide omega
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate peptide omega.id: 4
pdbx validate peptide omega.pdb model num: 1
pdbx validate peptide omega.auth asym id 1: C
pdbx validate peptide omega.auth asym id 2: C
pdbx validate peptide omega.auth comp id 1: THR
pdbx validate peptide omega.auth comp id 2: GLU
pdbx validate peptide omega.auth seq id 1: 39
pdbx validate peptide omega.auth seq id 2: 40
pdbx validate peptide omega.omega: 148.14

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_peptide_omega/5
type: pdbx validate peptide omega
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate peptide omega.id: 5
pdbx validate peptide omega.pdb model num: 1
pdbx validate peptide omega.auth asym id 1: C
pdbx validate peptide omega.auth asym id 2: C
pdbx validate peptide omega.auth comp id 1: HIS
pdbx validate peptide omega.auth comp id 2: THR
pdbx validate peptide omega.auth seq id 1: 71
pdbx validate peptide omega.auth seq id 2: 72
pdbx validate peptide omega.omega: 145.51

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_rmsd_angle/1
type: pdbx validate rmsd angle
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate rmsd angle.id: 1
pdbx validate rmsd angle.pdb model num: 1
pdbx validate rmsd angle.angle deviation: 3.27
pdbx validate rmsd angle.angle standard deviation: 0.5
pdbx validate rmsd angle.angle target value: 120.3
pdbx validate rmsd angle.angle value: 123.57
pdbx validate rmsd angle.auth asym id 1: A
pdbx validate rmsd angle.auth asym id 2: A
pdbx validate rmsd angle.auth asym id 3: A
pdbx validate rmsd angle.auth atom id 1: NE
pdbx validate rmsd angle.auth atom id 2: CZ
pdbx validate rmsd angle.auth atom id 3: NH1
pdbx validate rmsd angle.auth comp id 1: ARG
pdbx validate rmsd angle.auth comp id 2: ARG
pdbx validate rmsd angle.auth comp id 3: ARG
pdbx validate rmsd angle.auth seq id 1: 217
pdbx validate rmsd angle.auth seq id 2: 217
pdbx validate rmsd angle.auth seq id 3: 217
pdbx validate rmsd angle.linker flag: N

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_rmsd_angle/2
type: pdbx validate rmsd angle
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate rmsd angle.id: 2
pdbx validate rmsd angle.pdb model num: 1
pdbx validate rmsd angle.angle deviation: -20.32
pdbx validate rmsd angle.angle standard deviation: 1.8
pdbx validate rmsd angle.angle target value: 114
pdbx validate rmsd angle.angle value: 93.68
pdbx validate rmsd angle.auth asym id 1: B
pdbx validate rmsd angle.auth asym id 2: B
pdbx validate rmsd angle.auth asym id 3: B
pdbx validate rmsd angle.auth atom id 1: CA
pdbx validate rmsd angle.auth atom id 2: CB
pdbx validate rmsd angle.auth atom id 3: SG
pdbx validate rmsd angle.auth comp id 1: CYS
pdbx validate rmsd angle.auth comp id 2: CYS
pdbx validate rmsd angle.auth comp id 3: CYS
pdbx validate rmsd angle.auth seq id 1: 327
pdbx validate rmsd angle.auth seq id 2: 327
pdbx validate rmsd angle.auth seq id 3: 327
pdbx validate rmsd angle.linker flag: N

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_rmsd_bond/1
type: pdbx validate rmsd bond
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate rmsd bond.id: 1
pdbx validate rmsd bond.pdb model num: 1
pdbx validate rmsd bond.auth asym id 1: D
pdbx validate rmsd bond.auth asym id 2: D
pdbx validate rmsd bond.auth atom id 1: CG
pdbx validate rmsd bond.auth atom id 2: CD
pdbx validate rmsd bond.auth comp id 1: GLU
pdbx validate rmsd bond.auth comp id 2: GLU
pdbx validate rmsd bond.auth seq id 1: 277
pdbx validate rmsd bond.auth seq id 2: 277
pdbx validate rmsd bond.bond deviation: 0.101
pdbx validate rmsd bond.bond standard deviation: 0.015
pdbx validate rmsd bond.bond target value: 1.515
pdbx validate rmsd bond.bond value: 1.616
pdbx validate rmsd bond.linker flag: N

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_symm_contact/1
type: pdbx validate symm contact
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate symm contact.id: 1
pdbx validate symm contact.pdb model num: 1
pdbx validate symm contact.auth asym id 1: C
pdbx validate symm contact.auth asym id 2: A
pdbx validate symm contact.auth atom id 1: NH1
pdbx validate symm contact.auth atom id 2: O
pdbx validate symm contact.auth comp id 1: ARG
pdbx validate symm contact.auth comp id 2: HOH
pdbx validate symm contact.auth seq id 1: 217
pdbx validate symm contact.auth seq id 2: 2189
pdbx validate symm contact.dist: 1.96
pdbx validate symm contact.site symmetry 1: 1_555
pdbx validate symm contact.site symmetry 2: 2_555

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/1
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 1
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 127
pdbx validate torsion.phi: -154.92
pdbx validate torsion.psi: 45.32

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/2
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 2
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 145
pdbx validate torsion.phi: 52.3
pdbx validate torsion.psi: 83.58

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/3
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 3
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: VAL
pdbx validate torsion.auth seq id: 164
pdbx validate torsion.phi: 73.87
pdbx validate torsion.psi: 131.35

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/4
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 4
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: SER
pdbx validate torsion.auth seq id: 181
pdbx validate torsion.phi: -146.92
pdbx validate torsion.psi: -143.55

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/5
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 5
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: THR
pdbx validate torsion.auth seq id: 290
pdbx validate torsion.phi: -127.58
pdbx validate torsion.psi: -169

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/6
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 6
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: LEU
pdbx validate torsion.auth seq id: 296
pdbx validate torsion.phi: 156.31
pdbx validate torsion.psi: 145.55

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/7
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 7
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: B
pdbx validate torsion.auth comp id: TYR
pdbx validate torsion.auth seq id: 178
pdbx validate torsion.phi: 65.28
pdbx validate torsion.psi: -8.88

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/8
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 8
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: B
pdbx validate torsion.auth comp id: TRP
pdbx validate torsion.auth seq id: 372
pdbx validate torsion.phi: -35.49
pdbx validate torsion.psi: 107.98

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/9
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 9
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: THR
pdbx validate torsion.auth seq id: 14
pdbx validate torsion.phi: -29.05
pdbx validate torsion.psi: -55.34

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/10
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 10
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: THR
pdbx validate torsion.auth seq id: 41
pdbx validate torsion.phi: -149.46
pdbx validate torsion.psi: 27.83

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/11
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 11
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 127
pdbx validate torsion.phi: -153.93
pdbx validate torsion.psi: 47.92

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/12
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 12
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 145
pdbx validate torsion.phi: 51.74
pdbx validate torsion.psi: 85.66

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/13
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 13
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: VAL
pdbx validate torsion.auth seq id: 164
pdbx validate torsion.phi: 72.89
pdbx validate torsion.psi: 132.9

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/14
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 14
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: C
pdbx validate torsion.auth comp id: SER
pdbx validate torsion.auth seq id: 181
pdbx validate torsion.phi: -149.77
pdbx validate torsion.psi: -144.83

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/15
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 15
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: D
pdbx validate torsion.auth comp id: ASP
pdbx validate torsion.auth seq id: 177
pdbx validate torsion.phi: -105.41
pdbx validate torsion.psi: -83.17

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/16
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 16
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: D
pdbx validate torsion.auth comp id: TYR
pdbx validate torsion.auth seq id: 178
pdbx validate torsion.phi: -48.98
pdbx validate torsion.psi: 1.17

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/17
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 17
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: D
pdbx validate torsion.auth comp id: TRP
pdbx validate torsion.auth seq id: 372
pdbx validate torsion.phi: -38.02
pdbx validate torsion.psi: 110.53

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/18
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 18
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: D
pdbx validate torsion.auth comp id: LYS
pdbx validate torsion.auth seq id: 417
pdbx validate torsion.phi: -39.54
pdbx validate torsion.psi: -35.77

http://rdf.wwpdb.org/pdb/4CFN/pdbx_validate_torsion/19
type: pdbx validate torsion
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
pdbx validate torsion.id: 19
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: D
pdbx validate torsion.auth comp id: ASN
pdbx validate torsion.auth seq id: 431
pdbx validate torsion.phi: 30.98
pdbx validate torsion.psi: 54.86

4CFN,X-RAY DIFFRACTION
type: refine
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
refine.entry id: 4CFN
refine.pdbx refine id: X-RAY DIFFRACTION
refine.b iso mean: 36.479
refine.aniso B11: -0.11
refine.aniso B12: 0
refine.aniso B13: 0
refine.aniso B22: -1.82
refine.aniso B23: 0
refine.aniso B33: 1.93
refine.correlation coeff fo to fc: 0.945
refine.correlation coeff fo to fc free: 0.915
refine.details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
refine.ls r factor r free: 0.24087
refine.ls r factor r work: 0.19714
refine.ls r factor obs: 0.19932
refine.ls d res high: 2.2
refine.ls d res low: 99.5
refine.ls number reflns r free: 3463
refine.ls number reflns obs: 65427
refine.ls percent reflns r free: 5
refine.ls percent reflns obs: 91.17
refine.overall SU b: 14.098
refine.overall SU ML: 0.173
refine.pdbx r free selection details: RANDOM
refine.pdbx diffrn id: 1
refine.pdbx ls cross valid method: THROUGHOUT
refine.pdbx method to determine struct: MOLECULAR REPLACEMENT
refine.pdbx overall ESU r: 0.269
refine.pdbx overall ESU r free: 0.212
refine.pdbx solvent ion probe radii: 0.8
refine.pdbx solvent shrinkage radii: 0.8
refine.pdbx solvent vdw probe radii: 1.2
refine.pdbx starting model: PDB ENTRY 1H1S
refine.pdbx stereochemistry target values: MAXIMUM LIKELIHOOD
refine.solvent model details: MASK

LAST,X-RAY DIFFRACTION
type: refine hist
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine hist.cycle id: LAST
refine hist.pdbx refine id: X-RAY DIFFRACTION
refine hist.d res high: 2.2
refine hist.d res low: 99.5
refine hist.number atoms solvent: 555
refine hist.number atoms total: 9495
refine hist.pdbx number atoms ligand: 60
refine hist.pdbx number atoms nucleic acid: 0
refine hist.pdbx number atoms protein: 8880

X-RAY DIFFRACTION,r bond refined d
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_refined_d
refine ls restr.dev ideal: 0.017
refine ls restr.dev ideal target: 0.019
refine ls restr.number: 9207

X-RAY DIFFRACTION,r bond other d
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_bond_other_d
refine ls restr.dev ideal: 0.002
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 8967

X-RAY DIFFRACTION,r angle refined deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_refined_deg
refine ls restr.dev ideal: 1.826
refine ls restr.dev ideal target: 1.983
refine ls restr.number: 12503

X-RAY DIFFRACTION,r angle other deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_angle_other_deg
refine ls restr.dev ideal: 2.492
refine ls restr.dev ideal target: 3.001
refine ls restr.number: 20678

X-RAY DIFFRACTION,r dihedral angle 1 deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_1_deg
refine ls restr.dev ideal: 6.321
refine ls restr.dev ideal target: 5
refine ls restr.number: 1104

X-RAY DIFFRACTION,r dihedral angle 2 deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_2_deg
refine ls restr.dev ideal: 42.02
refine ls restr.dev ideal target: 23.852
refine ls restr.number: 392

X-RAY DIFFRACTION,r dihedral angle 3 deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_3_deg
refine ls restr.dev ideal: 17.517
refine ls restr.dev ideal target: 15
refine ls restr.number: 1612

X-RAY DIFFRACTION,r dihedral angle 4 deg
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_dihedral_angle_4_deg
refine ls restr.dev ideal: 17.412
refine ls restr.dev ideal target: 15
refine ls restr.number: 45

X-RAY DIFFRACTION,r chiral restr
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_chiral_restr
refine ls restr.dev ideal: 0.161
refine ls restr.dev ideal target: 0.2
refine ls restr.number: 1411

X-RAY DIFFRACTION,r gen planes refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_refined
refine ls restr.dev ideal: 0.008
refine ls restr.dev ideal target: 0.021
refine ls restr.number: 10091

X-RAY DIFFRACTION,r gen planes other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_gen_planes_other
refine ls restr.dev ideal: 0.008
refine ls restr.dev ideal target: 0.02
refine ls restr.number: 2058

X-RAY DIFFRACTION,r nbd refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_refined

X-RAY DIFFRACTION,r nbd other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbd_other

X-RAY DIFFRACTION,r nbtor refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_refined

X-RAY DIFFRACTION,r nbtor other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_nbtor_other

X-RAY DIFFRACTION,r xyhbond nbd refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_refined

X-RAY DIFFRACTION,r xyhbond nbd other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_xyhbond_nbd_other

X-RAY DIFFRACTION,r metal ion refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_refined

X-RAY DIFFRACTION,r metal ion other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_metal_ion_other

X-RAY DIFFRACTION,r symmetry vdw refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_refined

X-RAY DIFFRACTION,r symmetry vdw other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_vdw_other

X-RAY DIFFRACTION,r symmetry hbond refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_refined

X-RAY DIFFRACTION,r symmetry hbond other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_hbond_other

X-RAY DIFFRACTION,r symmetry metal ion refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_refined

X-RAY DIFFRACTION,r symmetry metal ion other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_symmetry_metal_ion_other

X-RAY DIFFRACTION,r mcbond it
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_it
refine ls restr.dev ideal: 0.611
refine ls restr.dev ideal target: 1.439
refine ls restr.number: 4425

X-RAY DIFFRACTION,r mcbond other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcbond_other
refine ls restr.dev ideal: 0.611
refine ls restr.dev ideal target: 1.439
refine ls restr.number: 4424

X-RAY DIFFRACTION,r mcangle it
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_it
refine ls restr.dev ideal: 0.947
refine ls restr.dev ideal target: 2.155
refine ls restr.number: 5526

X-RAY DIFFRACTION,r mcangle other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_mcangle_other

X-RAY DIFFRACTION,r scbond it
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_it
refine ls restr.dev ideal: 0.741
refine ls restr.dev ideal target: 1.541
refine ls restr.number: 4782

X-RAY DIFFRACTION,r scbond other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scbond_other

X-RAY DIFFRACTION,r scangle it
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_it

X-RAY DIFFRACTION,r scangle other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_scangle_other

X-RAY DIFFRACTION,r long range B refined
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_refined

X-RAY DIFFRACTION,r long range B other
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_long_range_B_other

X-RAY DIFFRACTION,r rigid bond restr
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_rigid_bond_restr

X-RAY DIFFRACTION,r sphericity free
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_free

X-RAY DIFFRACTION,r sphericity bonded
type: refine ls restr
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: r_sphericity_bonded

2.2,X-RAY DIFFRACTION
type: refine ls shell
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
refine ls shell.d res high: 2.2
refine ls shell.pdbx refine id: X-RAY DIFFRACTION
refine ls shell.r factor r free: 0.346
refine ls shell.r factor r work: 0.3
refine ls shell.d res low: 2.257
refine ls shell.number reflns r free: 220
refine ls shell.number reflns r work: 3914
refine ls shell.pdbx total number of bins used: 20
refine ls shell.percent reflns obs: 74.78

http://rdf.wwpdb.org/pdb/4CFN/reflns/1
type: reflns
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
reflns.pdbx ordinal: 1
reflns.d resolution high: 2.2
reflns.d resolution low: 2.32
reflns.entry id: 4CFN
reflns.number obs: 68917
reflns.observed criterion sigma i: 0
reflns.pdbx rmerge i obs: 0.07
reflns.pdbx diffrn id: 1
reflns.pdbx net i over sigma i: 10.8
reflns.pdbx redundancy: 2.33
reflns.percent possible obs: 92

http://rdf.wwpdb.org/pdb/4CFN/reflns_shell/1
type: reflns shell
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reflns shell.pdbx ordinal: 1
reflns shell.rmerge i obs: 0.42
reflns shell.d res high: 2.2
reflns shell.d res low: 2.32
reflns shell.mean i over sig i obs: 2.1
reflns shell.pdbx diffrn id: 1
reflns shell.percent possible all: 77.4

http://rdf.wwpdb.org/pdb/4CFN/software/1
type: software
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
software.pdbx ordinal: 1
software.classification: refinement
software.name: REFMAC
software.version: 5.8.0049

http://rdf.wwpdb.org/pdb/4CFN/software/2
type: software
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
software.pdbx ordinal: 2
software.classification: data reduction
software.name: MOSFLM

http://rdf.wwpdb.org/pdb/4CFN/software/3
type: software
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
software.pdbx ordinal: 3
software.classification: data scaling
software.name: SCALA

http://rdf.wwpdb.org/pdb/4CFN/software/4
type: software
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
software.pdbx ordinal: 4
software.classification: phasing
software.name: PHASER

4CFN
type: struct
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
struct.entry id: 4CFN
struct.title: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/E
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/3
struct asym.id: E
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/F
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/4
struct asym.id: F
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/G
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/3
struct asym.id: G
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/H
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/4
struct asym.id: H
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/I
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/5
struct asym.id: I
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/J
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/5
struct asym.id: J
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/K
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/5
struct asym.id: K
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_asym/L
type: struct asym
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/5
struct asym.id: L
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

http://rdf.wwpdb.org/pdb/4CFN/struct_biol/1
type: struct biol
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct biol.id: 1

HELX P1
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P1
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 0
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 4
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLU
struct conf.end auth seq id: 2
struct conf.end label asym id: A
struct conf.end label comp id: GLU
struct conf.end label seq id: 6
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 1
struct conf.pdbx PDB helix length: 3

HELX P
referenced by struct conf: HELX P1
referenced by struct conf: HELX P2
referenced by struct conf: HELX P3
referenced by struct conf: HELX P4
referenced by struct conf: HELX P5
referenced by struct conf: HELX P6
referenced by struct conf: HELX P7
referenced by struct conf: HELX P8
referenced by struct conf: HELX P9
referenced by struct conf: HELX P10
referenced by struct conf: HELX P11
referenced by struct conf: HELX P12
referenced by struct conf: HELX P13
referenced by struct conf: HELX P14
referenced by struct conf: HELX P15
referenced by struct conf: HELX P16
referenced by struct conf: HELX P17
referenced by struct conf: HELX P18
referenced by struct conf: HELX P19
referenced by struct conf: HELX P20
referenced by struct conf: HELX P21
referenced by struct conf: HELX P22
referenced by struct conf: HELX P23
referenced by struct conf: HELX P24
referenced by struct conf: HELX P25
referenced by struct conf: HELX P26
referenced by struct conf: HELX P27
referenced by struct conf: HELX P28
referenced by struct conf: HELX P29
referenced by struct conf: HELX P30
referenced by struct conf: HELX P31
referenced by struct conf: HELX P32
referenced by struct conf: HELX P33
referenced by struct conf: HELX P34
referenced by struct conf: HELX P35
referenced by struct conf: HELX P36
referenced by struct conf: HELX P37
referenced by struct conf: HELX P38
referenced by struct conf: HELX P39
referenced by struct conf: HELX P40
referenced by struct conf: HELX P41
referenced by struct conf: HELX P42
referenced by struct conf: HELX P43
referenced by struct conf: HELX P44
referenced by struct conf: HELX P45
referenced by struct conf: HELX P46
referenced by struct conf: HELX P47
referenced by struct conf: HELX P48
referenced by struct conf: HELX P49
referenced by struct conf: HELX P50
referenced by struct conf: HELX P51
referenced by struct conf: HELX P52
referenced by struct conf: HELX P53
referenced by struct conf: HELX P54
referenced by struct conf: HELX P55
referenced by struct conf: HELX P56
referenced by struct conf: HELX P57
referenced by struct conf: HELX P58
referenced by struct conf: HELX P59
referenced by struct conf: HELX P60
referenced by struct conf: HELX P61
referenced by struct conf: HELX P62
type: struct conf type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct conf type.id: HELX_P

HELX P2
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P2
struct conf.beg auth asym id: A
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 45
struct conf.beg label asym id: A
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 49
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 58
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 62
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 2
struct conf.pdbx PDB helix length: 14

HELX P3
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P3
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 87
struct conf.beg label asym id: A
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 91
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: SER
struct conf.end auth seq id: 94
struct conf.end label asym id: A
struct conf.end label comp id: SER
struct conf.end label seq id: 98
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 3
struct conf.pdbx PDB helix length: 8

HELX P4
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P4
struct conf.beg auth asym id: A
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 100
struct conf.beg label asym id: A
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 104
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 121
struct conf.end label asym id: A
struct conf.end label comp id: HIS
struct conf.end label seq id: 125
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 4
struct conf.pdbx PDB helix length: 22

HELX P5
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P5
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 129
struct conf.beg label asym id: A
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 133
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 131
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 135
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 5
struct conf.pdbx PDB helix length: 3

HELX P6
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P6
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 165
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 169
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 169
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 173
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 6
struct conf.pdbx PDB helix length: 5

HELX P7
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P7
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 170
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 174
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 175
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 179
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 7
struct conf.pdbx PDB helix length: 6

HELX P8
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P8
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 182
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 186
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 199
struct conf.end label asym id: A
struct conf.end label comp id: ARG
struct conf.end label seq id: 203
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 8
struct conf.pdbx PDB helix length: 18

HELX P9
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P9
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 207
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 211
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 220
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 224
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 9
struct conf.pdbx PDB helix length: 14

HELX P10
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P10
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 229
struct conf.beg label asym id: A
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 233
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: MET
struct conf.end auth seq id: 233
struct conf.end label asym id: A
struct conf.end label comp id: MET
struct conf.end label seq id: 237
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 10
struct conf.pdbx PDB helix length: 5

HELX P11
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P11
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 247
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 251
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 252
struct conf.end label asym id: A
struct conf.end label comp id: VAL
struct conf.end label seq id: 256
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 11
struct conf.pdbx PDB helix length: 6

HELX P12
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P12
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 256
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 260
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 267
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 271
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 12
struct conf.pdbx PDB helix length: 12

HELX P13
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P13
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 276
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 280
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 281
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 285
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 13
struct conf.pdbx PDB helix length: 6

HELX P14
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P14
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 282
struct conf.beg label asym id: A
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 286
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 287
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 291
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 14
struct conf.pdbx PDB helix length: 6

HELX P15
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P15
struct conf.beg auth asym id: B
struct conf.beg auth comp id: TYR
struct conf.beg auth seq id: 178
struct conf.beg label asym id: B
struct conf.beg label comp id: TYR
struct conf.beg label seq id: 4
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: CYS
struct conf.end auth seq id: 193
struct conf.end label asym id: B
struct conf.end label comp id: CYS
struct conf.end label seq id: 19
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 15
struct conf.pdbx PDB helix length: 16

HELX P16
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P16
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 198
struct conf.beg label asym id: B
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 24
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 203
struct conf.end label asym id: B
struct conf.end label comp id: GLN
struct conf.end label seq id: 29
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 16
struct conf.pdbx PDB helix length: 6

HELX P17
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P17
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 207
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 33
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 225
struct conf.end label asym id: B
struct conf.end label comp id: TYR
struct conf.end label seq id: 51
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 17
struct conf.pdbx PDB helix length: 19

HELX P18
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P18
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLN
struct conf.beg auth seq id: 228
struct conf.beg label asym id: B
struct conf.beg label comp id: GLN
struct conf.beg label seq id: 54
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: SER
struct conf.end auth seq id: 244
struct conf.end label asym id: B
struct conf.end label comp id: SER
struct conf.end label seq id: 70
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 18
struct conf.pdbx PDB helix length: 17

HELX P19
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P19
struct conf.beg auth asym id: B
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 249
struct conf.beg label asym id: B
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 75
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLU
struct conf.end auth seq id: 269
struct conf.end label asym id: B
struct conf.end label comp id: GLU
struct conf.end label seq id: 95
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 19
struct conf.pdbx PDB helix length: 21

HELX P20
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P20
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 274
struct conf.beg label asym id: B
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 100
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: THR
struct conf.end auth seq id: 282
struct conf.end label asym id: B
struct conf.end label comp id: THR
struct conf.end label seq id: 108
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 20
struct conf.pdbx PDB helix length: 9

HELX P21
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P21
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 287
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 113
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 302
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 128
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 21
struct conf.pdbx PDB helix length: 16

HELX P22
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P22
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 310
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 136
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 320
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 146
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 22
struct conf.pdbx PDB helix length: 11

HELX P23
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P23
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 326
struct conf.beg label asym id: B
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 152
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 341
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 167
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 23
struct conf.pdbx PDB helix length: 16

HELX P24
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P24
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 343
struct conf.beg label asym id: B
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 169
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 348
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 174
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 24
struct conf.pdbx PDB helix length: 6

HELX P25
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P25
struct conf.beg auth asym id: B
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 351
struct conf.beg label asym id: B
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 177
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 369
struct conf.end label asym id: B
struct conf.end label comp id: GLY
struct conf.end label seq id: 195
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 25
struct conf.pdbx PDB helix length: 19

HELX P26
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P26
struct conf.beg auth asym id: B
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 373
struct conf.beg label asym id: B
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 199
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 381
struct conf.end label asym id: B
struct conf.end label comp id: GLY
struct conf.end label seq id: 207
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 26
struct conf.pdbx PDB helix length: 9

HELX P27
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P27
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 383
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 209
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 401
struct conf.end label asym id: B
struct conf.end label comp id: ALA
struct conf.end label seq id: 227
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 27
struct conf.pdbx PDB helix length: 19

HELX P28
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P28
struct conf.beg auth asym id: B
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 402
struct conf.beg label asym id: B
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 228
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 404
struct conf.end label asym id: B
struct conf.end label comp id: HIS
struct conf.end label seq id: 230
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 28
struct conf.pdbx PDB helix length: 3

HELX P29
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P29
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLN
struct conf.beg auth seq id: 407
struct conf.beg label asym id: B
struct conf.beg label comp id: GLN
struct conf.beg label seq id: 233
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 413
struct conf.end label asym id: B
struct conf.end label comp id: TYR
struct conf.end label seq id: 239
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 29
struct conf.pdbx PDB helix length: 7

HELX P30
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P30
struct conf.beg auth asym id: B
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 414
struct conf.beg label asym id: B
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 240
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 419
struct conf.end label asym id: B
struct conf.end label comp id: HIS
struct conf.end label seq id: 245
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 30
struct conf.pdbx PDB helix length: 6

HELX P31
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P31
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 420
struct conf.beg label asym id: B
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 246
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 424
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 250
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 31
struct conf.pdbx PDB helix length: 5

HELX P32
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P32
struct conf.beg auth asym id: C
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 0
struct conf.beg label asym id: C
struct conf.beg label comp id: SER
struct conf.beg label seq id: 4
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: GLU
struct conf.end auth seq id: 2
struct conf.end label asym id: C
struct conf.end label comp id: GLU
struct conf.end label seq id: 6
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 32
struct conf.pdbx PDB helix length: 3

HELX P33
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P33
struct conf.beg auth asym id: C
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 45
struct conf.beg label asym id: C
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 49
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 58
struct conf.end label asym id: C
struct conf.end label comp id: LEU
struct conf.end label seq id: 62
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 33
struct conf.pdbx PDB helix length: 14

HELX P34
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P34
struct conf.beg auth asym id: C
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 87
struct conf.beg label asym id: C
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 91
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: SER
struct conf.end auth seq id: 94
struct conf.end label asym id: C
struct conf.end label comp id: SER
struct conf.end label seq id: 98
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 34
struct conf.pdbx PDB helix length: 8

HELX P35
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P35
struct conf.beg auth asym id: C
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 100
struct conf.beg label asym id: C
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 104
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 121
struct conf.end label asym id: C
struct conf.end label comp id: HIS
struct conf.end label seq id: 125
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 35
struct conf.pdbx PDB helix length: 22

HELX P36
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P36
struct conf.beg auth asym id: C
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 129
struct conf.beg label asym id: C
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 133
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 131
struct conf.end label asym id: C
struct conf.end label comp id: GLN
struct conf.end label seq id: 135
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 36
struct conf.pdbx PDB helix length: 3

HELX P37
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P37
struct conf.beg auth asym id: C
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 165
struct conf.beg label asym id: C
struct conf.beg label comp id: THR
struct conf.beg label seq id: 169
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 169
struct conf.end label asym id: C
struct conf.end label comp id: ARG
struct conf.end label seq id: 173
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 37
struct conf.pdbx PDB helix length: 5

HELX P38
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P38
struct conf.beg auth asym id: C
struct conf.beg auth comp id: ALA
struct conf.beg auth seq id: 170
struct conf.beg label asym id: C
struct conf.beg label comp id: ALA
struct conf.beg label seq id: 174
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 175
struct conf.end label asym id: C
struct conf.end label comp id: LEU
struct conf.end label seq id: 179
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 38
struct conf.pdbx PDB helix length: 6

HELX P39
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P39
struct conf.beg auth asym id: C
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 182
struct conf.beg label asym id: C
struct conf.beg label comp id: THR
struct conf.beg label seq id: 186
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: ARG
struct conf.end auth seq id: 199
struct conf.end label asym id: C
struct conf.end label comp id: ARG
struct conf.end label seq id: 203
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 39
struct conf.pdbx PDB helix length: 18

HELX P40
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P40
struct conf.beg auth asym id: C
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 207
struct conf.beg label asym id: C
struct conf.beg label comp id: SER
struct conf.beg label seq id: 211
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 220
struct conf.end label asym id: C
struct conf.end label comp id: GLY
struct conf.end label seq id: 224
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 40
struct conf.pdbx PDB helix length: 14

HELX P41
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P41
struct conf.beg auth asym id: C
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 229
struct conf.beg label asym id: C
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 233
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: MET
struct conf.end auth seq id: 233
struct conf.end label asym id: C
struct conf.end label comp id: MET
struct conf.end label seq id: 237
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 41
struct conf.pdbx PDB helix length: 5

HELX P42
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P42
struct conf.beg auth asym id: C
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 247
struct conf.beg label asym id: C
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 251
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 252
struct conf.end label asym id: C
struct conf.end label comp id: VAL
struct conf.end label seq id: 256
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 42
struct conf.pdbx PDB helix length: 6

HELX P43
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P43
struct conf.beg auth asym id: C
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 256
struct conf.beg label asym id: C
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 260
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 267
struct conf.end label asym id: C
struct conf.end label comp id: LEU
struct conf.end label seq id: 271
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 43
struct conf.pdbx PDB helix length: 12

HELX P44
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P44
struct conf.beg auth asym id: C
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 276
struct conf.beg label asym id: C
struct conf.beg label comp id: SER
struct conf.beg label seq id: 280
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 282
struct conf.end label asym id: C
struct conf.end label comp id: ALA
struct conf.end label seq id: 286
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 44
struct conf.pdbx PDB helix length: 7

HELX P45
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P45
struct conf.beg auth asym id: C
struct conf.beg auth comp id: HIS
struct conf.beg auth seq id: 283
struct conf.beg label asym id: C
struct conf.beg label comp id: HIS
struct conf.beg label seq id: 287
struct conf.conf type id: HELX_P
struct conf.end auth asym id: C
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 287
struct conf.end label asym id: C
struct conf.end label comp id: GLN
struct conf.end label seq id: 291
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 45
struct conf.pdbx PDB helix length: 5

HELX P46
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P46
struct conf.beg auth asym id: D
struct conf.beg auth comp id: TYR
struct conf.beg auth seq id: 178
struct conf.beg label asym id: D
struct conf.beg label comp id: TYR
struct conf.beg label seq id: 4
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: CYS
struct conf.end auth seq id: 193
struct conf.end label asym id: D
struct conf.end label comp id: CYS
struct conf.end label seq id: 19
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 46
struct conf.pdbx PDB helix length: 16

HELX P47
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P47
struct conf.beg auth asym id: D
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 198
struct conf.beg label asym id: D
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 24
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 203
struct conf.end label asym id: D
struct conf.end label comp id: GLN
struct conf.end label seq id: 29
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 47
struct conf.pdbx PDB helix length: 6

HELX P48
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P48
struct conf.beg auth asym id: D
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 207
struct conf.beg label asym id: D
struct conf.beg label comp id: THR
struct conf.beg label seq id: 33
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 225
struct conf.end label asym id: D
struct conf.end label comp id: TYR
struct conf.end label seq id: 51
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 48
struct conf.pdbx PDB helix length: 19

HELX P49
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P49
struct conf.beg auth asym id: D
struct conf.beg auth comp id: GLN
struct conf.beg auth seq id: 228
struct conf.beg label asym id: D
struct conf.beg label comp id: GLN
struct conf.beg label seq id: 54
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: SER
struct conf.end auth seq id: 244
struct conf.end label asym id: D
struct conf.end label comp id: SER
struct conf.end label seq id: 70
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 49
struct conf.pdbx PDB helix length: 17

HELX P50
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P50
struct conf.beg auth asym id: D
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 249
struct conf.beg label asym id: D
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 75
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: GLU
struct conf.end auth seq id: 269
struct conf.end label asym id: D
struct conf.end label comp id: GLU
struct conf.end label seq id: 95
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 50
struct conf.pdbx PDB helix length: 21

HELX P51
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P51
struct conf.beg auth asym id: D
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 274
struct conf.beg label asym id: D
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 100
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: THR
struct conf.end auth seq id: 282
struct conf.end label asym id: D
struct conf.end label comp id: THR
struct conf.end label seq id: 108
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 51
struct conf.pdbx PDB helix length: 9

HELX P52
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P52
struct conf.beg auth asym id: D
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 287
struct conf.beg label asym id: D
struct conf.beg label comp id: THR
struct conf.beg label seq id: 113
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 302
struct conf.end label asym id: D
struct conf.end label comp id: LEU
struct conf.end label seq id: 128
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 52
struct conf.pdbx PDB helix length: 16

HELX P53
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P53
struct conf.beg auth asym id: D
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 310
struct conf.beg label asym id: D
struct conf.beg label comp id: THR
struct conf.beg label seq id: 136
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 320
struct conf.end label asym id: D
struct conf.end label comp id: LEU
struct conf.end label seq id: 146
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 53
struct conf.pdbx PDB helix length: 11

HELX P54
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P54
struct conf.beg auth asym id: D
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 326
struct conf.beg label asym id: D
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 152
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 341
struct conf.end label asym id: D
struct conf.end label comp id: LEU
struct conf.end label seq id: 167
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 54
struct conf.pdbx PDB helix length: 16

HELX P55
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P55
struct conf.beg auth asym id: D
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 343
struct conf.beg label asym id: D
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 169
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 348
struct conf.end label asym id: D
struct conf.end label comp id: LEU
struct conf.end label seq id: 174
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 55
struct conf.pdbx PDB helix length: 6

HELX P56
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P56
struct conf.beg auth asym id: D
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 351
struct conf.beg label asym id: D
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 177
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 369
struct conf.end label asym id: D
struct conf.end label comp id: GLY
struct conf.end label seq id: 195
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 56
struct conf.pdbx PDB helix length: 19

HELX P57
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P57
struct conf.beg auth asym id: D
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 373
struct conf.beg label asym id: D
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 199
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 381
struct conf.end label asym id: D
struct conf.end label comp id: GLY
struct conf.end label seq id: 207
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 57
struct conf.pdbx PDB helix length: 9

HELX P58
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P58
struct conf.beg auth asym id: D
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 383
struct conf.beg label asym id: D
struct conf.beg label comp id: THR
struct conf.beg label seq id: 209
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 401
struct conf.end label asym id: D
struct conf.end label comp id: ALA
struct conf.end label seq id: 227
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 58
struct conf.pdbx PDB helix length: 19

HELX P59
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P59
struct conf.beg auth asym id: D
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 402
struct conf.beg label asym id: D
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 228
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 404
struct conf.end label asym id: D
struct conf.end label comp id: HIS
struct conf.end label seq id: 230
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 59
struct conf.pdbx PDB helix length: 3

HELX P60
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P60
struct conf.beg auth asym id: D
struct conf.beg auth comp id: GLN
struct conf.beg auth seq id: 407
struct conf.beg label asym id: D
struct conf.beg label comp id: GLN
struct conf.beg label seq id: 233
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 413
struct conf.end label asym id: D
struct conf.end label comp id: TYR
struct conf.end label seq id: 239
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: 60
struct conf.pdbx PDB helix length: 7

HELX P61
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P61
struct conf.beg auth asym id: D
struct conf.beg auth comp id: LYS
struct conf.beg auth seq id: 414
struct conf.beg label asym id: D
struct conf.beg label comp id: LYS
struct conf.beg label seq id: 240
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 419
struct conf.end label asym id: D
struct conf.end label comp id: HIS
struct conf.end label seq id: 245
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 61
struct conf.pdbx PDB helix length: 6

HELX P62
type: struct conf
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conf type: HELX P
struct conf.id: HELX_P62
struct conf.beg auth asym id: D
struct conf.beg auth comp id: GLY
struct conf.beg auth seq id: 420
struct conf.beg label asym id: D
struct conf.beg label comp id: GLY
struct conf.beg label seq id: 246
struct conf.conf type id: HELX_P
struct conf.end auth asym id: D
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 424
struct conf.end label asym id: D
struct conf.end label comp id: LEU
struct conf.end label seq id: 250
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: 62
struct conf.pdbx PDB helix length: 5

covale1
type: struct conn
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conn type: covale
struct conn.id: covale1
struct conn.conn type id: covale
struct conn.pdbx dist value: 1.33
struct conn.pdbx leaving atom flag: both
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: TYR
struct conn.ptnr1 auth seq id: 159
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: C
struct conn.ptnr1 label comp id: TYR
struct conn.ptnr1 label seq id: 163
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: TPO
struct conn.ptnr2 auth seq id: 160
struct conn.ptnr2 label asym id: A
struct conn.ptnr2 label atom id: N
struct conn.ptnr2 label comp id: TPO
struct conn.ptnr2 label seq id: 164
struct conn.ptnr2 symmetry: 1_555

covale
referenced by struct conn: covale1
referenced by struct conn: covale2
referenced by struct conn: covale3
referenced by struct conn: covale4
type: struct conn type
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct conn type.id: covale

covale2
type: struct conn
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conn type: covale
struct conn.id: covale2
struct conn.conn type id: covale
struct conn.pdbx dist value: 1.33
struct conn.pdbx leaving atom flag: both
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: TPO
struct conn.ptnr1 auth seq id: 160
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: C
struct conn.ptnr1 label comp id: TPO
struct conn.ptnr1 label seq id: 164
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HIS
struct conn.ptnr2 auth seq id: 161
struct conn.ptnr2 label asym id: A
struct conn.ptnr2 label atom id: N
struct conn.ptnr2 label comp id: HIS
struct conn.ptnr2 label seq id: 165
struct conn.ptnr2 symmetry: 1_555

covale3
type: struct conn
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conn type: covale
struct conn.id: covale3
struct conn.conn type id: covale
struct conn.pdbx dist value: 1.342
struct conn.pdbx leaving atom flag: both
struct conn.ptnr1 auth asym id: C
struct conn.ptnr1 auth comp id: TYR
struct conn.ptnr1 auth seq id: 159
struct conn.ptnr1 label asym id: C
struct conn.ptnr1 label atom id: C
struct conn.ptnr1 label comp id: TYR
struct conn.ptnr1 label seq id: 163
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: C
struct conn.ptnr2 auth comp id: TPO
struct conn.ptnr2 auth seq id: 160
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: N
struct conn.ptnr2 label comp id: TPO
struct conn.ptnr2 label seq id: 164
struct conn.ptnr2 symmetry: 1_555

covale4
type: struct conn
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct conn type: covale
struct conn.id: covale4
struct conn.conn type id: covale
struct conn.pdbx dist value: 1.339
struct conn.pdbx leaving atom flag: both
struct conn.ptnr1 auth asym id: C
struct conn.ptnr1 auth comp id: TPO
struct conn.ptnr1 auth seq id: 160
struct conn.ptnr1 label asym id: C
struct conn.ptnr1 label atom id: C
struct conn.ptnr1 label comp id: TPO
struct conn.ptnr1 label seq id: 164
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: C
struct conn.ptnr2 auth comp id: HIS
struct conn.ptnr2 auth seq id: 161
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: N
struct conn.ptnr2 label comp id: HIS
struct conn.ptnr2 label seq id: 165
struct conn.ptnr2 symmetry: 1_555

4CFN
type: struct keywords
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
struct keywords.entry id: 4CFN
struct keywords.pdbx keywords: CELL CYCLE
struct keywords.text: CELL CYCLE, CYCLIN DEPENDENT KINASES, STRUCTURE-BASED DRUG DESIGN, CONFORMATIONAL RESTRAINT, REVERSED BINDING MODE

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/1
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 1
struct mon prot cis.auth asym id: A
struct mon prot cis.auth comp id: VAL
struct mon prot cis.auth seq id: 154
struct mon prot cis.label asym id: A
struct mon prot cis.label comp id: VAL
struct mon prot cis.label seq id: 158
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: A
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 155
struct mon prot cis.pdbx label asym id 2: A
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 159
struct mon prot cis.pdbx omega angle: -2.72

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/2
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 2
struct mon prot cis.auth asym id: A
struct mon prot cis.auth comp id: LEU
struct mon prot cis.auth seq id: 296
struct mon prot cis.label asym id: A
struct mon prot cis.label comp id: LEU
struct mon prot cis.label seq id: 300
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: A
struct mon prot cis.pdbx auth comp id 2: ARG
struct mon prot cis.pdbx auth seq id 2: 297
struct mon prot cis.pdbx label asym id 2: A
struct mon prot cis.pdbx label comp id 2: ARG
struct mon prot cis.pdbx label seq id 2: 301
struct mon prot cis.pdbx omega angle: -24.70

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/3
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 3
struct mon prot cis.auth asym id: B
struct mon prot cis.auth comp id: GLN
struct mon prot cis.auth seq id: 323
struct mon prot cis.label asym id: B
struct mon prot cis.label comp id: GLN
struct mon prot cis.label seq id: 149
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: B
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 324
struct mon prot cis.pdbx label asym id 2: B
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 150
struct mon prot cis.pdbx omega angle: -6.40

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/4
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 4
struct mon prot cis.auth asym id: B
struct mon prot cis.auth comp id: ASP
struct mon prot cis.auth seq id: 345
struct mon prot cis.label asym id: B
struct mon prot cis.label comp id: ASP
struct mon prot cis.label seq id: 171
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: B
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 346
struct mon prot cis.pdbx label asym id 2: B
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 172
struct mon prot cis.pdbx omega angle: 6.12

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/5
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 5
struct mon prot cis.auth asym id: C
struct mon prot cis.auth comp id: GLU
struct mon prot cis.auth seq id: 40
struct mon prot cis.label asym id: C
struct mon prot cis.label comp id: GLU
struct mon prot cis.label seq id: 44
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: C
struct mon prot cis.pdbx auth comp id 2: THR
struct mon prot cis.pdbx auth seq id 2: 41
struct mon prot cis.pdbx label asym id 2: C
struct mon prot cis.pdbx label comp id 2: THR
struct mon prot cis.pdbx label seq id 2: 45
struct mon prot cis.pdbx omega angle: -17.90

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/6
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 6
struct mon prot cis.auth asym id: C
struct mon prot cis.auth comp id: VAL
struct mon prot cis.auth seq id: 154
struct mon prot cis.label asym id: C
struct mon prot cis.label comp id: VAL
struct mon prot cis.label seq id: 158
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: C
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 155
struct mon prot cis.pdbx label asym id 2: C
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 159
struct mon prot cis.pdbx omega angle: -1.49

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/7
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 7
struct mon prot cis.auth asym id: D
struct mon prot cis.auth comp id: GLN
struct mon prot cis.auth seq id: 323
struct mon prot cis.label asym id: D
struct mon prot cis.label comp id: GLN
struct mon prot cis.label seq id: 149
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: D
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 324
struct mon prot cis.pdbx label asym id 2: D
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 150
struct mon prot cis.pdbx omega angle: -4.73

http://rdf.wwpdb.org/pdb/4CFN/struct_mon_prot_cis/8
type: struct mon prot cis
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct mon prot cis.pdbx id: 8
struct mon prot cis.auth asym id: D
struct mon prot cis.auth comp id: ASP
struct mon prot cis.auth seq id: 345
struct mon prot cis.label asym id: D
struct mon prot cis.label comp id: ASP
struct mon prot cis.label seq id: 171
struct mon prot cis.pdbx PDB model num: 1
struct mon prot cis.pdbx auth asym id 2: D
struct mon prot cis.pdbx auth comp id 2: PRO
struct mon prot cis.pdbx auth seq id 2: 346
struct mon prot cis.pdbx label asym id 2: D
struct mon prot cis.pdbx label comp id 2: PRO
struct mon prot cis.pdbx label seq id 2: 172
struct mon prot cis.pdbx omega angle: 10.55

http://rdf.wwpdb.org/pdb/4CFN/struct_ref/1
type: struct ref
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/1
struct ref.id: 1
struct ref.db code: CDK2_HUMAN
struct ref.db name: UNP
struct ref.entity id: 1
struct ref.pdbx db accession: P24941
link to uniprot: uniprot:P24941
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1

uniprot:P24941

http://rdf.wwpdb.org/pdb/4CFN/struct_ref/2
type: struct ref
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entity: http://rdf.wwpdb.org/pdb/4CFN/entity/2
struct ref.id: 2
struct ref.db code: CCNA2_HUMAN
struct ref.db name: UNP
struct ref.entity id: 2
struct ref.pdbx db accession: P20248
link to uniprot: uniprot:P20248
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/4
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/2

uniprot:P20248

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1
type: struct ref seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref: http://rdf.wwpdb.org/pdb/4CFN/struct_ref/1
struct ref seq.align id: 1
struct ref seq.db align beg: 1
struct ref seq.db align end: 298
struct ref seq.pdbx PDB id code: 4CFN
struct ref seq.pdbx auth seq align beg: 1
struct ref seq.pdbx auth seq align end: 298
struct ref seq.pdbx db accession: P24941
struct ref seq.pdbx strand id: A
struct ref seq.ref id: 1
struct ref seq.seq align beg: 5
struct ref seq.seq align end: 302
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/4
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/1
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/2
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/3

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/2
type: struct ref seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref: http://rdf.wwpdb.org/pdb/4CFN/struct_ref/2
struct ref seq.align id: 2
struct ref seq.db align beg: 175
struct ref seq.db align end: 432
struct ref seq.pdbx PDB id code: 4CFN
struct ref seq.pdbx auth seq align beg: 175
struct ref seq.pdbx auth seq align end: 432
struct ref seq.pdbx db accession: P20248
struct ref seq.pdbx strand id: B
struct ref seq.ref id: 2
struct ref seq.seq align beg: 1
struct ref seq.seq align end: 258

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
type: struct ref seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref: http://rdf.wwpdb.org/pdb/4CFN/struct_ref/1
struct ref seq.align id: 3
struct ref seq.db align beg: 1
struct ref seq.db align end: 298
struct ref seq.pdbx PDB id code: 4CFN
struct ref seq.pdbx auth seq align beg: 1
struct ref seq.pdbx auth seq align end: 298
struct ref seq.pdbx db accession: P24941
struct ref seq.pdbx strand id: C
struct ref seq.ref id: 1
struct ref seq.seq align beg: 5
struct ref seq.seq align end: 302
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/8
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/5
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/6
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/7

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/4
type: struct ref seq
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref: http://rdf.wwpdb.org/pdb/4CFN/struct_ref/2
struct ref seq.align id: 4
struct ref seq.db align beg: 175
struct ref seq.db align end: 432
struct ref seq.pdbx PDB id code: 4CFN
struct ref seq.pdbx auth seq align beg: 175
struct ref seq.pdbx auth seq align end: 432
struct ref seq.pdbx db accession: P20248
struct ref seq.pdbx strand id: D
struct ref seq.ref id: 2
struct ref seq.seq align beg: 1
struct ref seq.seq align end: 258

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/1
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 1
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -3
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/2
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 2
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: PRO
struct ref seq dif.pdbx auth seq num: -2
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/3
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 3
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -1
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 3

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/4
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 4
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 0
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 4

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/5
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
struct ref seq dif.pdbx ordinal: 5
struct ref seq dif.align id: 3
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -3
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: C
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/6
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
struct ref seq dif.pdbx ordinal: 6
struct ref seq dif.align id: 3
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: PRO
struct ref seq dif.pdbx auth seq num: -2
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: C
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/7
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
struct ref seq dif.pdbx ordinal: 7
struct ref seq dif.align id: 3
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: -1
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: C
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 3

http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq_dif/8
type: struct ref seq dif
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct ref seq: http://rdf.wwpdb.org/pdb/4CFN/struct_ref_seq/3
struct ref seq dif.pdbx ordinal: 8
struct ref seq dif.align id: 3
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 0
struct ref seq dif.pdbx pdb id code: 4CFN
struct ref seq dif.pdbx pdb strand id: C
struct ref seq dif.pdbx seq db accession code: P24941
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 4

1,2,AA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AA
struct sheet order.sense: anti-parallel

2,3,AA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: AA
struct sheet order.sense: anti-parallel

3,4,AA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet order.range id 1: 3
struct sheet order.range id 2: 4
struct sheet order.sheet id: AA
struct sheet order.sense: anti-parallel

4,5,AA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet order.range id 1: 4
struct sheet order.range id 2: 5
struct sheet order.sheet id: AA
struct sheet order.sense: anti-parallel

1,2,AB
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AB
struct sheet order.sense: anti-parallel

2,3,AB
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: AB
struct sheet order.sense: anti-parallel

1,2,AC
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AC
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: AC
struct sheet order.sense: anti-parallel

1,2,CA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: CA
struct sheet order.sense: anti-parallel

2,3,CA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: CA
struct sheet order.sense: anti-parallel

3,4,CA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet order.range id 1: 3
struct sheet order.range id 2: 4
struct sheet order.sheet id: CA
struct sheet order.sense: anti-parallel

4,5,CA
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet order.range id 1: 4
struct sheet order.range id 2: 5
struct sheet order.sheet id: CA
struct sheet order.sense: anti-parallel

1,2,CB
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: CB
struct sheet order.sense: anti-parallel

2,3,CB
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
struct sheet order.range id 1: 2
struct sheet order.range id 2: 3
struct sheet order.sheet id: CB
struct sheet order.sense: anti-parallel

1,2,CC
type: struct sheet order
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CC
struct sheet order.range id 1: 1
struct sheet order.range id 2: 2
struct sheet order.sheet id: CC
struct sheet order.sense: anti-parallel

1,AA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet range.id: 1
struct sheet range.sheet id: AA
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: PHE
struct sheet range.beg auth seq id: 4
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: PHE
struct sheet range.beg label seq id: 8
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: GLY
struct sheet range.end auth seq id: 11
struct sheet range.end label asym id: A
struct sheet range.end label comp id: GLY
struct sheet range.end label seq id: 15

2,AA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet range.id: 2
struct sheet range.sheet id: AA
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 17
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 21
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ASN
struct sheet range.end auth seq id: 23
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ASN
struct sheet range.end label seq id: 27

3,AA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet range.id: 3
struct sheet range.sheet id: AA
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 29
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 33
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ARG
struct sheet range.end auth seq id: 36
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ARG
struct sheet range.end label seq id: 40

4,AA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet range.id: 4
struct sheet range.sheet id: AA
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LYS
struct sheet range.beg auth seq id: 75
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LYS
struct sheet range.beg label seq id: 79
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: GLU
struct sheet range.end auth seq id: 81
struct sheet range.end label asym id: A
struct sheet range.end label comp id: GLU
struct sheet range.end label seq id: 85

5,AA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AA
struct sheet range.id: 5
struct sheet range.sheet id: AA
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 66
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 70
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: HIS
struct sheet range.end auth seq id: 71
struct sheet range.end label asym id: A
struct sheet range.end label comp id: HIS
struct sheet range.end label seq id: 75

1,AB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
struct sheet range.id: 1
struct sheet range.sheet id: AB
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: GLN
struct sheet range.beg auth seq id: 85
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: GLN
struct sheet range.beg label seq id: 89
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ASP
struct sheet range.end auth seq id: 86
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ASP
struct sheet range.end label seq id: 90

2,AB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
struct sheet range.id: 2
struct sheet range.sheet id: AB
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 133
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 137
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ILE
struct sheet range.end auth seq id: 135
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ILE
struct sheet range.end label seq id: 139

3,AB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AB
struct sheet range.id: 3
struct sheet range.sheet id: AB
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ILE
struct sheet range.beg auth seq id: 141
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ILE
struct sheet range.beg label seq id: 145
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 143
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 147

1,AC
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AC
struct sheet range.id: 1
struct sheet range.sheet id: AC
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 123
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 127
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 124
struct sheet range.end label asym id: A
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 128

2,AC
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: AC
struct sheet range.id: 2
struct sheet range.sheet id: AC
struct sheet range.beg auth asym id: A
struct sheet range.beg auth comp id: ARG
struct sheet range.beg auth seq id: 150
struct sheet range.beg label asym id: A
struct sheet range.beg label comp id: ARG
struct sheet range.beg label seq id: 154
struct sheet range.end auth asym id: A
struct sheet range.end auth comp id: ALA
struct sheet range.end auth seq id: 151
struct sheet range.end label asym id: A
struct sheet range.end label comp id: ALA
struct sheet range.end label seq id: 155

1,CA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet range.id: 1
struct sheet range.sheet id: CA
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: PHE
struct sheet range.beg auth seq id: 4
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: PHE
struct sheet range.beg label seq id: 8
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: GLY
struct sheet range.end auth seq id: 11
struct sheet range.end label asym id: C
struct sheet range.end label comp id: GLY
struct sheet range.end label seq id: 15

2,CA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet range.id: 2
struct sheet range.sheet id: CA
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 17
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 21
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: ASN
struct sheet range.end auth seq id: 23
struct sheet range.end label asym id: C
struct sheet range.end label comp id: ASN
struct sheet range.end label seq id: 27

3,CA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet range.id: 3
struct sheet range.sheet id: CA
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 29
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 33
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: ARG
struct sheet range.end auth seq id: 36
struct sheet range.end label asym id: C
struct sheet range.end label comp id: ARG
struct sheet range.end label seq id: 40

4,CA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet range.id: 4
struct sheet range.sheet id: CA
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: LYS
struct sheet range.beg auth seq id: 75
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: LYS
struct sheet range.beg label seq id: 79
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: GLU
struct sheet range.end auth seq id: 81
struct sheet range.end label asym id: C
struct sheet range.end label comp id: GLU
struct sheet range.end label seq id: 85

5,CA
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CA
struct sheet range.id: 5
struct sheet range.sheet id: CA
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 66
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 70
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: HIS
struct sheet range.end auth seq id: 71
struct sheet range.end label asym id: C
struct sheet range.end label comp id: HIS
struct sheet range.end label seq id: 75

1,CB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
struct sheet range.id: 1
struct sheet range.sheet id: CB
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: GLN
struct sheet range.beg auth seq id: 85
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: GLN
struct sheet range.beg label seq id: 89
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: ASP
struct sheet range.end auth seq id: 86
struct sheet range.end label asym id: C
struct sheet range.end label comp id: ASP
struct sheet range.end label seq id: 90

2,CB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
struct sheet range.id: 2
struct sheet range.sheet id: CB
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: LEU
struct sheet range.beg auth seq id: 133
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: LEU
struct sheet range.beg label seq id: 137
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: ILE
struct sheet range.end auth seq id: 135
struct sheet range.end label asym id: C
struct sheet range.end label comp id: ILE
struct sheet range.end label seq id: 139

3,CB
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CB
struct sheet range.id: 3
struct sheet range.sheet id: CB
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: ILE
struct sheet range.beg auth seq id: 141
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: ILE
struct sheet range.beg label seq id: 145
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 143
struct sheet range.end label asym id: C
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 147

1,CC
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CC
struct sheet range.id: 1
struct sheet range.sheet id: CC
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: VAL
struct sheet range.beg auth seq id: 123
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: VAL
struct sheet range.beg label seq id: 127
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: LEU
struct sheet range.end auth seq id: 124
struct sheet range.end label asym id: C
struct sheet range.end label comp id: LEU
struct sheet range.end label seq id: 128

2,CC
type: struct sheet range
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct sheet: CC
struct sheet range.id: 2
struct sheet range.sheet id: CC
struct sheet range.beg auth asym id: C
struct sheet range.beg auth comp id: ARG
struct sheet range.beg auth seq id: 150
struct sheet range.beg label asym id: C
struct sheet range.beg label comp id: ARG
struct sheet range.beg label seq id: 154
struct sheet range.end auth asym id: C
struct sheet range.end auth comp id: ALA
struct sheet range.end auth seq id: 151
struct sheet range.end label asym id: C
struct sheet range.end label comp id: ALA
struct sheet range.end label seq id: 155

AC1
type: struct site
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct site.id: AC1
struct site.details: BINDING SITE FOR RESIDUE JYM A 1298
struct site.pdbx auth asym id: A
struct site.pdbx auth comp id: JYM
struct site.pdbx auth seq id: 1298
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 10
referenced by struct site gen: 10,AC1
referenced by struct site gen: 1,AC1
referenced by struct site gen: 2,AC1
referenced by struct site gen: 3,AC1
referenced by struct site gen: 4,AC1
referenced by struct site gen: 5,AC1
referenced by struct site gen: 6,AC1
referenced by struct site gen: 7,AC1
referenced by struct site gen: 8,AC1
referenced by struct site gen: 9,AC1

AC2
type: struct site
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct site.id: AC2
struct site.details: BINDING SITE FOR RESIDUE JYM C 1295
struct site.pdbx auth asym id: C
struct site.pdbx auth comp id: JYM
struct site.pdbx auth seq id: 1295
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 16
referenced by struct site gen: 26,AC2
referenced by struct site gen: 11,AC2
referenced by struct site gen: 12,AC2
referenced by struct site gen: 13,AC2
referenced by struct site gen: 14,AC2
referenced by struct site gen: 15,AC2
referenced by struct site gen: 16,AC2
referenced by struct site gen: 17,AC2
referenced by struct site gen: 18,AC2
referenced by struct site gen: 19,AC2
referenced by struct site gen: 20,AC2
referenced by struct site gen: 21,AC2
referenced by struct site gen: 22,AC2
referenced by struct site gen: 23,AC2
referenced by struct site gen: 24,AC2
referenced by struct site gen: 25,AC2

AC3
type: struct site
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct site.id: AC3
struct site.details: BINDING SITE FOR RESIDUE DTT B 1433
struct site.pdbx auth asym id: B
struct site.pdbx auth comp id: DTT
struct site.pdbx auth seq id: 1433
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 3
referenced by struct site gen: 29,AC3
referenced by struct site gen: 27,AC3
referenced by struct site gen: 28,AC3

AC4
type: struct site
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
struct site.id: AC4
struct site.details: BINDING SITE FOR RESIDUE DTT D 1433
struct site.pdbx auth asym id: D
struct site.pdbx auth comp id: DTT
struct site.pdbx auth seq id: 1433
struct site.pdbx evidence code: Software
struct site.pdbx num residues: 4
referenced by struct site gen: 33,AC4
referenced by struct site gen: 30,AC4
referenced by struct site gen: 31,AC4
referenced by struct site gen: 32,AC4

1,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 1
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: GLU
struct site gen.auth seq id: 12
struct site gen.label asym id: A
struct site gen.label comp id: GLU
struct site gen.label seq id: 16
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

2,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 2
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 31
struct site gen.label asym id: A
struct site gen.label comp id: ALA
struct site gen.label seq id: 35
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

3,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 3
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: PHE
struct site gen.auth seq id: 80
struct site gen.label asym id: A
struct site gen.label comp id: PHE
struct site gen.label seq id: 84
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

4,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 4
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 83
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 87
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

5,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 5
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HIS
struct site gen.auth seq id: 84
struct site gen.label asym id: A
struct site gen.label comp id: HIS
struct site gen.label seq id: 88
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

6,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 6
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 85
struct site gen.label asym id: A
struct site gen.label comp id: GLN
struct site gen.label seq id: 89
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

7,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 7
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 134
struct site gen.label asym id: A
struct site gen.label comp id: LEU
struct site gen.label seq id: 138
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

8,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 8
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2014
struct site gen.label asym id: I
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

9,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 9
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2041
struct site gen.label asym id: I
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

10,AC1
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC1
struct site gen.id: 10
struct site gen.site id: AC1
struct site gen.auth asym id: A
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2193
struct site gen.label asym id: I
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 10
struct site gen.symmetry: 1_555

11,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 11
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: GLY
struct site gen.auth seq id: 11
struct site gen.label asym id: C
struct site gen.label comp id: GLY
struct site gen.label seq id: 15
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

12,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 12
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: GLU
struct site gen.auth seq id: 12
struct site gen.label asym id: C
struct site gen.label comp id: GLU
struct site gen.label seq id: 16
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

13,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 13
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: GLY
struct site gen.auth seq id: 13
struct site gen.label asym id: C
struct site gen.label comp id: GLY
struct site gen.label seq id: 17
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

14,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 14
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: VAL
struct site gen.auth seq id: 18
struct site gen.label asym id: C
struct site gen.label comp id: VAL
struct site gen.label seq id: 22
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

15,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 15
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: ALA
struct site gen.auth seq id: 31
struct site gen.label asym id: C
struct site gen.label comp id: ALA
struct site gen.label seq id: 35
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

16,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 16
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: PHE
struct site gen.auth seq id: 80
struct site gen.label asym id: C
struct site gen.label comp id: PHE
struct site gen.label seq id: 84
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

17,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 17
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 83
struct site gen.label asym id: C
struct site gen.label comp id: LEU
struct site gen.label seq id: 87
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

18,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 18
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HIS
struct site gen.auth seq id: 84
struct site gen.label asym id: C
struct site gen.label comp id: HIS
struct site gen.label seq id: 88
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

19,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 19
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 85
struct site gen.label asym id: C
struct site gen.label comp id: GLN
struct site gen.label seq id: 89
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

20,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 20
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 131
struct site gen.label asym id: C
struct site gen.label comp id: GLN
struct site gen.label seq id: 135
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

21,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 21
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 134
struct site gen.label asym id: C
struct site gen.label comp id: LEU
struct site gen.label seq id: 138
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

22,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 22
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2020
struct site gen.label asym id: K
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

23,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 23
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2033
struct site gen.label asym id: K
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

24,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 24
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2050
struct site gen.label asym id: K
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

25,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 25
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2052
struct site gen.label asym id: K
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

26,AC2
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC2
struct site gen.id: 26
struct site gen.site id: AC2
struct site gen.auth asym id: C
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2123
struct site gen.label asym id: K
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 16
struct site gen.symmetry: 1_555

27,AC3
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC3
struct site gen.id: 27
struct site gen.site id: AC3
struct site gen.auth asym id: B
struct site gen.auth comp id: TRP
struct site gen.auth seq id: 217
struct site gen.label asym id: B
struct site gen.label comp id: TRP
struct site gen.label seq id: 43
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_555

28,AC3
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC3
struct site gen.id: 28
struct site gen.site id: AC3
struct site gen.auth asym id: B
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2031
struct site gen.label asym id: J
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_555

29,AC3
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC3
struct site gen.id: 29
struct site gen.site id: AC3
struct site gen.auth asym id: B
struct site gen.auth comp id: HOH
struct site gen.auth seq id: 2151
struct site gen.label asym id: J
struct site gen.label comp id: HOH
struct site gen.pdbx num res: 3
struct site gen.symmetry: 1_555

30,AC4
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC4
struct site gen.id: 30
struct site gen.site id: AC4
struct site gen.auth asym id: C
struct site gen.auth comp id: LEU
struct site gen.auth seq id: 96
struct site gen.label asym id: C
struct site gen.label comp id: LEU
struct site gen.label seq id: 100
struct site gen.pdbx num res: 4
struct site gen.symmetry: 3_556

31,AC4
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC4
struct site gen.id: 31
struct site gen.site id: AC4
struct site gen.auth asym id: C
struct site gen.auth comp id: THR
struct site gen.auth seq id: 97
struct site gen.label asym id: C
struct site gen.label comp id: THR
struct site gen.label seq id: 101
struct site gen.pdbx num res: 4
struct site gen.symmetry: 3_556

32,AC4
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC4
struct site gen.id: 32
struct site gen.site id: AC4
struct site gen.auth asym id: D
struct site gen.auth comp id: TRP
struct site gen.auth seq id: 217
struct site gen.label asym id: D
struct site gen.label comp id: TRP
struct site gen.label seq id: 43
struct site gen.pdbx num res: 4
struct site gen.symmetry: 1_555

33,AC4
type: struct site gen
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to struct site: AC4
struct site gen.id: 33
struct site gen.site id: AC4
struct site gen.auth asym id: D
struct site gen.auth comp id: GLN
struct site gen.auth seq id: 254
struct site gen.label asym id: D
struct site gen.label comp id: GLN
struct site gen.label seq id: 80
struct site gen.pdbx num res: 4
struct site gen.symmetry: 1_555

4CFN
type: symmetry
of datablock: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
reference to entry: 4CFN
symmetry.entry id: 4CFN
symmetry.int tables number: 19
symmetry.space group name H-M: P 21 21 21