mouse ZNRF3 ectodomain crystal form V, disulfide-bridged S90C variant
Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
ETGKETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLCAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELD PKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQHLGTKH HHHHH
ZEBRAFISH ZNRF3 ECTODOMAIN CRYSTAL FORM I
ZEBRAFISH ZNRF3 ECTODOMAIN CRYSTAL FORM II
XENOPUS ZNRF3 ECTODOMAIN CRYSTAL FORM II
MOUSE ZNRF3 ECTODOMAIN IN COMPLEX WITH MOUSE RSPO2 FU1 -FU2 CRYSTAL FORM I
MOUSE ZNRF3 ECTODOMAIN IN COMPLEX WITH XENOPUS RSPO2 FU1-FU2 (SELENO MET) CRYSTAL FORM I
MOUSE ZNRF3 ECTODOMAIN IN COMPLEX WITH XENOPUS RSPO2 FU1-FU2 (SELENO MET) CRYSTAL FORM II
XENOPUS ZNRF3 ECTODOMAIN IN COMPLEX WITH XENOPUS RSPO2 FU1-FU2 CRYSTAL FORM I
XENOPUS ZNRF3 ECTODOMAIN IN COMPLEX WITH XENOPUS RSPO2 FU1-FU2 CRYSTAL FORM II
XENOPUS RNF43 ECTODOMAIN IN COMPLEX WITH XENOPUS RSPO2 FU1-FU2
SHEET DETERMINATION METHOD: DSSP THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 7-STRANDED BARREL THIS IS REPRESENTED BY A 8-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL.
HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
E3 UBIQUITIN-PROTEIN LIGASE ZNRF3 (E.C.6.3.2.-)
LIGASE, WNT, RNF43, LGR4, LGR5, LGR6, RSPO, R-SPONDIN, R-SPO, RSPO1, RSPO2, RSPO3, RSPO4, RECEPTOR, MEMBRANE, SIGNALLING