Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A

SMRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVK
LLGAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLAD
FGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPP
TLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE

0.2M NAI, 0.1M BISTRISPROPANE PH 6.5, 20% PEG3350, 10% ETHYLENE GLYCOL

CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 BOUND TO SU11274

CRYSTAL STRUCTURE OF HUMAN SERINE THREONINE KINASE-10 BOUND TO 4-[(2,4-DICHLORO-5-METHOXYPHENYL)AMINO]-6 - METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY] QUINOLINE-3-CARBONITRILE APPARENTLY MODIFIED THROUGH RADIATION DAMAGE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

RKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLL
GAYYHDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFG
VSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTL
LTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEE