Crystal Structure of the Y3:STAT1ND complex

Structural Basis of the Inhibition of STAT1 Activity by Sendai Virus C Protein.

FIXED EXIST Si 111 DOUBLE CRYSTAL MONOCHROMATOR

Signal transducer and activator of transcription 1-alpha/beta

Transcription factor ISGF-3 components p91/p84

MNHKVHHHHHHHHMSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQ
YSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQ

MNHKVHHHHHHHHMLETLINKIYTGPLGEELVQTLYLRIWAMEETPESLKILQMREDIRDQVLKMKTERWLRTLIRGEKT
KLKDFQKRYEEVHPYLMKEKVEQVIMEEAWSLAAHIVQE

30% PEG400, 0.2M CaCl2, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 298K

the model was re-refined by using phenix program to reduce the R factor and R free.

alpha protein, interferon inhibition, signal transduction, transcriptional activation, TRANSCRIPTION-VIRAL PROTEIN complex

MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQ
HNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQ

HMLETLINKIYTGPLGEELVQTLYLRIWAMEETPESLKILQMREDIRDQVLKMKTERWLRTLIRGEKTKLKDFQKRYEEV
HPYLMKEKVEQVIMEEAWSLAAHIVQE