Crystal structure of the human APOBEC3C having HIV-1 Vif-binding interface

Probable DNA dC->dU-editing enzyme APOBEC-3C

MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKRRSVVSWKTGVFRNQVDSETHCHAERCFLSWFCDDIL
SPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIFTARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENF
VYNDNEPFKPWKGLKTNFRLLKRRLRESLQ

Bicine, PEG 6000, L-Arginine HCl, pH 9.0, vapor diffusion, hanging drop, temperature 293K

APOBEC3C, SIVagm, metal-binding, single domain, Z2, antiviral defense, host-virus interaction, HYDROLASE, HIV, HIV-1 Vif, Bet